#Immuno Oncology Drugs Market Report

[mitalipingale]

The Immuno Oncology Drugs Market in 2023 is US$ 20.24 billion, and is expected to reach US$ 71.18 billion by 2031 at a CAGR of 17.02%.

[priteshwemarketresearch]

Ipilimumab Market by Platform, Type, Technology and End User Industry Statistics, Scope, Demand with Forecast 2034

Global Ipilimumab Market: A Growing Force in Cancer Immunotherapy

Ipilimumab Market under the brand name Yervoy, is a monoclonal antibody used in the treatment of various types of cancer. It works by blocking programmed cell death protein 1 (PD-1), a protein that helps cancer cells evade the immune system. Ipilimumab is often used in combination with other treatments, such as chemotherapy or other immune checkpoint inhibitors.

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Market Dynamics:

The global ipilimumab market is driven by several factors:

Increasing Prevalence of Cancers: The rising incidence of cancers worldwide, particularly melanoma, is a key driver of market growth.

Drug Efficacy: Ipilimumab has demonstrated significant efficacy in clinical trials, leading to increased adoption in treatment regimens.

Expanding Indications: Ongoing research is exploring the potential of ipilimumab for treating other cancer types, such as renal cell carcinoma and non-small cell lung cancer.

Competitive Landscape: While ipilimumab faces competition from other immune checkpoint inhibitors, its unique properties and clinical data have contributed to its market success.

Market Segmentation

The ipilimumab market can be segmented based on:

Cancer Type: Melanoma, renal cell carcinoma, non-small cell lung cancer, and other indications.

Treatment Stage: First-line, second-line, and third-line treatments.

Geography: North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa.

Market Challenges and Opportunities

High Drug Cost: The price of ipilimumab can be a significant barrier for patients and healthcare systems.

Reimbursement Challenges: Gaining insurance coverage for ipilimumab can be complex in some regions.

Emerging Competitors: The development of new immune checkpoint inhibitors and targeted therapies poses competition to ipilimumab.

Expanding Indications: The potential for ipilimumab to be approved for additional cancer types represents a significant growth opportunity.

Opportunities in the Ipilimumab Market

Expanding Indications: Ongoing research into new cancer indications provides ample opportunities for market expansion. Trials exploring the efficacy of ipilimumab in cancers like prostate cancer and other solid tumors could lead to new approvals and increased market potential.

Patient Access and Affordability: Efforts to improve patient access and reduce treatment costs could open new avenues for market growth. Innovations in pricing models, patient assistance programs, and insurance coverage can make ipilimumab more accessible to a broader patient population.

Biomarker Development: The development of biomarkers to identify patients who are most likely to benefit from ipilimumab treatment could enhance its clinical use and market adoption. Personalized medicine approaches can optimize treatment regimens and improve patient

Challenges Facing the Market

High Cost of Treatment: Ipilimumab, like many immunotherapies, is associated with a high cost. This can limit its accessibility and impact overall market growth. Addressing cost-related challenges and finding ways to make treatments more affordable is crucial.

Competitive Landscape: The immuno-oncology field is highly competitive, with numerous companies developing similar checkpoint inhibitors and combination therapies. Staying ahead in terms of innovation and clinical efficacy is essential for maintaining market position.

Adverse Effects and Tolerability: Managing the side effects of ipilimumab, which can include immune-related adverse events, remains a challenge. Ensuring that patients can tolerate the treatment while effectively managing these side effects is vital for sustained market success.

Competitive Strategies and Market Positioning

Strategic Partnerships: Collaborations between pharmaceutical companies, research institutions, and oncology centers are pivotal in advancing ipilimumab’s market reach. Strategic partnerships can lead to joint research efforts, shared resources, and enhanced market access.

Innovation and Differentiation: In a competitive Ipilimumab Market, differentiating ipilimumab from other immune checkpoint inhibitors is essential. Innovations such as novel drug formulations, improved delivery methods, or adjunctive therapies can enhance its appeal. Companies are also investing in next-generation immunotherapies to maintain a competitive edge.

Marketing and Education: Effective marketing strategies and educational initiatives play a key role in promoting ipilimumab. Awareness campaigns aimed at both healthcare professionals and patients can drive informed decision-making and increase adoption rates. Educational programs about the benefits, side effects, and management of ipilimumab are crucial for its successful integration into clinical practice.

Research and Clinical Advancements

Innovative Research: Cutting-edge research into the mechanisms of action of ipilimumab and its interactions with the immune system is advancing our understanding of its therapeutic potential. Research into biomarkers that predict response and resistance to ipilimumab can lead to more personalized treatment approaches and improved outcomes.

Combination Therapies: Ongoing clinical trials are exploring combinations of ipilimumab with other therapies, such as chemotherapy, radiotherapy, and targeted agents. These studies aim to enhance efficacy, reduce resistance, and improve patient outcomes. Positive results from these trials could expand the indications and Ipilimumab Market potential of ipilimumab.

Real-World Evidence: Collecting real-world evidence (RWE) is increasingly important in demonstrating the effectiveness of ipilimumab outside controlled clinical settings. RWE can provide insights into long-term outcomes, safety profiles, and patient experiences, supporting broader adoption and informed decision-making.

Future Outlook

The global ipilimumab market is expected to continue growing, driven by advancements in cancer research, expanding indications, and increased patient access. As the drug's efficacy is further established and reimbursement challenges are addressed, the market is poised for significant expansion.

The ipilimumab market is poised for continued growth, driven by advancements in cancer research, combination therapies, and expanding indications. While challenges such as cost and competition exist, the opportunities for innovation and patient access offer promising prospects. As the landscape of cancer treatment evolves, ipilimumab is likely to remain a key player in the immunotherapy arena, contributing to the ongoing quest for more effective and personalized cancer treatments.

Conclusion:

The ipilimumab market stands at a crossroads of significant potential and ongoing challenges. As a cornerstone of immuno-oncology, ipilimumab has already demonstrated its transformative impact on cancer treatment. However, its journey is far from complete, and the path forward involves navigating a landscape shaped by rapid advancements, regulatory complexities, and evolving patient needs.

[bhushans]

Unveiling the Power of Data: Global Breast Cancer Drug Market

The global breast cancer drug market is set for steady growth over the next decade. Valued at USD 10,733.1 million in 2023, the market is projected to reach approximately USD 12,012.1 million by 2033, with a compound annual growth rate (CAGR) of 1.1% during the forecast period.

The increasing prevalence of breast cancer and the continuous evolution of novel therapies are key factors driving this market expansion. Early detection remains crucial for the effective management and treatment of breast cancer, further bolstering the demand for advanced drug therapies.

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One of the most prevalent malignancies affecting women globally, breast cancer has a significant effect on public health. Improving patient outcomes and lowering the disease’s mortality rates depend on the creation of novel treatments as well as improvements in early detection techniques.

Breast cancer is caused by a multitude of factors, such as genetic mutations (abnormal variations), age, inheritance, lifestyle, and heredity. Researchers are looking into novel imaging modalities to assess anomalies during the early stages of the disease and trying to determine the impact of genetic changes on breast cancer.

Key Takeaways:

The global breast cancer drug market is projected to reach US$12,012.1 million by 2033, reflecting a rise from US$10,733.1 million in 2023.

This growth is expected at a moderate compound annual growth rate (CAGR) of 1.1% throughout the forecast period.

The rising prevalence of breast cancer and the development of novel therapies are key drivers for market expansion.

Competitive Landscape:

In August 2021, Pfizer Inc. and Trillium Therapeutics Inc. entered into a definitive agreement under which Pfizer will acquire Trillium, a clinical-stage immuno-oncology company developing innovative therapies for the treatment of cancer. Under the terms of the agreement, Pfizer will acquire all outstanding shares of Trillium not already owned by Pfizer for an implied equity value of $2.26 billion, or $18.50 per share, in cash.

In June 2022, Novartis announced new overall survival (OS) and quality of life (QoL) analyses which evaluated Kisqali® (ribociclib) plus endocrine therapy for patients with hormone receptor-positive/human epidermal growth factor receptor-negative (HR+/HER2-) advanced or metastatic breast cancer.

Key Companies Profiled:

F. Hoffmann-La Roche Ltd

Pfizer Inc.

AstraZeneca

Novartis International AG

Achieve Life Science

Bristol-Myers Squibb

Eisai Co. Ltd

AbbVie

Eli Lilly & Company

Celgene Corporation

Merck & Co.

Amgen Plc.

Celldex Therapeutics

Biocon Genzyme Corporation

Key Segments Covered in the Breast Cancer Drug Industry Analysis:

By Drug Class:

SERM (Selective Estrogen-Receptor Modulators)-based

Aromatase Inhibitors-based

Biologic Response Modifiers-based

Other Hormonal Therapies-based

By Distribution Channel:

Hospital Pharmacies

Pharmacies

Drug Stores

By Region:

North America

Latin America

Europe

Asia Pacific

Middle East & Africa

[fairfield-research]

Oncology Drugs Market Growth, Trends, Size, Share, Demand And Top Growing Companies 2031

In a landscape where the battle against cancer rages on, advancements in healthcare systems, public health measures, and novel pharmaceutical therapies have ushered in a new era of hope. According to the National Cancer Institute, the United States saw an estimated 1,806,590 new cancer cases and approximately 606,520 deaths due to the disease in 2020. However, over the past five decades, cancer survival rates have soared from 50% in 1970 to an impressive 70%, thanks to a trifecta of progress.

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Unprecedented Growth Trajectory: The global oncology therapy sales are forecasted to surpass US$ 300 billion by 2026, with oncology contributing 21.7% to total pharmaceutical sales. Fueling this growth are the top 10 pharmaceutical companies, which have declared oncology as their key focus area, driving multibillion-dollar M&A deals and strategic collaborations. Pfizer's acquisition of Array BioPharma for US$11 billion in 2019 and AbbVie's strategic partnership with Genmab for a bispecific antibody development deal worth US$3 billion are testament to this focus.

Diverse Indications Drive Demand: While oncology represents over 20 different indications, a significant portion of revenue stems from just five of them: breast cancer, multiple myeloma, non-small-cell lung carcinoma (NSCLC), prostate cancer, and non-Hodgkin's lymphoma (NHL), which collectively accounted for approximately 65% of the market in 2020. Moreover, with breast, lung, and colorectal cancers expected to collectively account for ~50% of all new cancer diagnoses by 2026, the demand for innovative therapies continues to surge.

Disruptive Trends Reshape Landscape: Innovation in oncology is accelerating, with disruptive technologies such as cell therapy, RNA therapy, viral vectors, and stem cell therapy gaining traction. Recent approvals of CAR-T cell therapies like Kymriah and Yescarta for acute lymphocytic leukemia (ALL) and diffuse large B-cell lymphoma (DLBCL) respectively signal a new frontier in cancer treatment. Precision medicine is also driving progress, with over 160 oncology biomarkers approved by 2019, paving the way for more targeted and effective therapies.

Impact of COVID-19: Despite remarkable progress, oncology has been among the worst-hit therapeutic areas amid the COVID-19 pandemic. Decreased demand for physician-administered products, disruptions in cancer screenings, and a decline in new clinical trials have posed significant challenges. However, the industry remains resilient, adapting to the evolving landscape and ensuring continued innovation.

Immuno-Oncology Leads the Way: Immuno-oncology sales are expected to soar to ~US$ 95 billion by 2026, with agents and protein kinase inhibitors comprising ~65% of sales. With over 550 active cell- and gene-therapy agents under clinical development, the future of cancer treatment looks promising. Investments in combination studies and the exploration of new mechanisms underscore the industry's commitment to advancing immuno-oncology therapies.Roche and Keytruda: Leading the Charge: In a highly concentrated market where the top 10 companies capture over 75% of the market value, F. Hoffmann-La Roche AG (Roche) and Merck & Co. stand out as leaders. While Roche maintains its global leadership position, Merck's Keytruda is poised to become the world's top-selling oncology

[lalsingh228-blog]

AI in Drug Discovery Market to See Huge Growth by 2029

Global AI in Drug Discovery Market Report from AMA Research highlights deep analysis on market characteristics, sizing, estimates and growth by segmentation, regional breakdowns & country along with competitive landscape, player’s market shares, and strategies that are key in the market. The exploration provides a 360° view and insights, highlighting major outcomes of the industry. These insights help the business decision-makers to formulate better business plans and make informed decisions to improved profitability. In addition, the study helps venture or private players in understanding the companies in more detail to make better informed decisions. Major Players in This Report Include, IBM Corporation (United States), Microsoft (United States), Google (United States), NVIDIA Corporation (United States), Atomwise, Inc. (United States), Deep Genomics (Canada), Cloud Pharmaceuticals (United States), Insilico Medicine (United States), Benevolent AI (United Kingdom), Exscientia (United Kingdom). Free Sample Report + All Related Graphs & Charts @: https://www.advancemarketanalytics.com/sample-report/127272-global-ai-in-drug-discovery-market Artificial intelligence for drug discovery is a technology that uses and different algorithms that value add in decision-making processes for drug discovery. The increasing cases of rare diseases and demand for personalized drugs are the major factor fueling the growth of the global Al for Drug Discovery marker. Market Drivers

Increasing Pressure on the Drug Manufacturer to Reduce Drug Price

Growing Number of Cross-Industry Collaborations and Partnerships

Market Trend

Research Applying AI to Drug Discovery is Accelerating

Data Sharing

Opportunities

Implementation of AI reduces researches and development gap in the drug manufacturing process and help in the targeted manufacturing of the drugs.

Huge Investments in Research & Developments

Challenges

Protecting Intellectual Property and Data

Enquire for customization in Report @: https://www.advancemarketanalytics.com/enquiry-before-buy/127272-global-ai-in-drug-discovery-market In this research study, the prime factors that are impelling the growth of the Global AI in Drug Discovery market report have been studied thoroughly in a bid to estimate the overall value and the size of this market by the end of the forecast period. The impact of the driving forces, limitations, challenges, and opportunities has been examined extensively. The key trends that manage the interest of the customers have also been interpreted accurately for the benefit of the readers. The AI in Drug Discovery market study is being classified by Application (Immuno-oncology, Neurodegenerative Diseases, Cardiovascular Diseases, Metabolic Diseases, Others), Technology (Machine Learning, Deep Learning, Others), End-User (Pharmaceutical & Biotechnology, Research Organizations, Academic & Government Institutes), Component (Software, Services) The report concludes with in-depth details on the business operations and financial structure of leading vendors in the Global AI in Drug Discovery market report, Overview of Key trends in the past and present are in reports that are reported to be beneficial for companies looking for venture businesses in this market. Information about the various marketing channels and well-known distributors in this market was also provided here. This study serves as a rich guide for established players and new players in this market. Get Reasonable Discount on This Premium Report @ https://www.advancemarketanalytics.com/request-discount/127272-global-ai-in-drug-discovery-market Extracts from Table of Contents AI in Drug Discovery Market Research Report Chapter 1 AI in Drug Discovery Market Overview Chapter 2 Global Economic Impact on Industry Chapter 3 Global Market Competition by Manufacturers Chapter 4 Global Revenue (Value, Volume*) by Region Chapter 5 Global Supplies (Production), Consumption, Export, Import by Regions Chapter 6 Global Revenue (Value, Volume*), Price* Trend by Type Chapter 7 Global Market Analysis by Application ………………….continued This report also analyzes the regulatory framework of the Global Markets AI in Drug Discovery Market Report to inform stakeholders about the various norms, regulations, this can have an impact. It also collects in-depth information from the detailed primary and secondary research techniques analyzed using the most efficient analysis tools. Based on the statistics gained from this systematic study, market research provides estimates for market participants and readers. Contact US : Craig Francis (PR & Marketing Manager) AMA Research & Media LLP Unit No. 429, Parsonage Road Edison, NJ New Jersey USA – 08837 Phone: +1 201 565 3262, +44 161 818 8166 sales@advancemarketanalytics.com

[pharmanucleus1]

Oncolytic Virus Therapies Market - Exploring Cancer Treatment Innovations in Coming Future

Oncolytic Virus Therapies Market: Overview 

The market size of the global?oncolytic virus therapies in the year 2019?is valued at 84.3 million and is predicted to reach 962 million by the year 2030?at an 26.28% CAGR during the forecast period.

Oncolytic viruses (OVs) are either naturally occurring or genetically modified. They only target and kill cancer cells while leaving healthy cells unharmed. This treatment, a cutting-edge approach to treating cancer patients, has had positive outcomes. Oncolytic virus therapies, which target DNA or RNA inside or outside the body, overlap biomedical research fields with similar therapeutic goals. Through genetic modification, these therapies attempt to treat an illness. The need to treat these chronic illnesses and the rising cancer incidence are the main factors driving the market growth. Cancer incidences have grown due to aging populations, population growth, and greater exposure to cancer risk factors. As awareness of these conditions rises, so does the demand for sophisticated cancer detection and treatment techniques, which is expected to drive market growth throughout the forecast period. 

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Additionally, it is projected that the market demand will grow more swiftly in the coming years due to the rise in demand for targeted cancer therapies, the rapid breakthroughs in cancer research and the rise in immuno-oncology drug approvals by the medical establishment backs. The drug does, however, occasionally cause some unpleasant side effects, including fever, chills, nausea, and soreness at the injection site. The expansion of the oncolytic viral therapies market's revenue is restricted. 

Oncolytic Virus Therapies Market Trends: 

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Oncolytic Virus Therapies Market Drivers: 

Increased Demand for Awareness Campaigns by Governments Around the World to Drive Growth 

The market expansion would be aided by several awareness initiatives being carried out by governments of developing nations worldwide to raise awareness of various cancer therapies. Due to increased public demand and knowledge, this action is expected to result in more patients being diagnosed with cancer early, improving market value and market share. Oncolytic medication availability for different malignancies is anticipated to propel market expansion throughout the market forecast period and lead to innovations and breakthroughs. 

Growing Number of Studies to Increase Demand and Augment Market Growth

The industry will rise as more research is done to discover new treatments for cancer and other disorders. Important market participants are participating in these trials to provide major discoveries that will raise public awareness and fuel the demand for immunotherapies. The study includes malignancies, including melanoma and breast cancer. Thus, combining these variables would spur public knowledge of oncolytic viruses and commercial expansion. 

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Oncolytic Virus Therapies Market: Restraints 

Treatment Side Effects That Could Limit Market Expansion

Oncolytic viruses may cause the immune system to target healthy cells, increasing the risk of infection due to the viruses' capacity to infect healthy cells and raise overall immunological activity systems. The expansion of the market value may be hampered by potential adverse effects such as fever, chills, nausea, exhaustion, flu-like symptoms, and discomfort following the therapy, as patients may carefully examine these concerns before seeking virus therapy. An imbalance may also hamper the market drivers and the market share of the service in the supply and demand of the materials needed for the treatments. Therefore, before making market investments, important industrial players and investors must consider these aspects. 

Oncolytic Virus Therapies Market: Segmentation 

The global oncolytic virus therapies market is segregated based on commercialized therapies, pipeline therapies, type of virus, and application.

By Type of Virus 

Based on the type of virus, the market segmentation is divided into a genetically engineered oncolytic virus (herpes simplex virus (HSV), adenovirus, vaccinia virus) and oncolytic wild-type virus?(reovirus (respiratory enteric orphan virus), newcastle disease virus (NDV), vesicular stomatitis virus (VSV)). The genetically engineered oncolytic virus category is anticipated to dominate the market over the market forecast period. The increasing utilization demand has driven the market share in this sector due to their high accuracy in delivering the gene to the specific region. The prevalence of cancer is rising, and as a primary treatment, genetically engineered oncolytic viruses are becoming more and more necessary. The corporations are forming alliances and contracts to expand their market share. 

By Application 

Based on application, the market segmentation is divided into the solid tumor (breast cancer, prostate cancer, lung cancer, glioblastoma, melanoma, other applications) and?hematological malignancies (lymphoma, leukemia, myeloma). The solid tumor category dominated the market and is anticipated to maintain its dominance over the forecast period due to an increase in the prevalence of malignant tumors, an increase in the use of oncolytic viruses to treat metastatic cancers because current treatment methods were ineffective, and improvements in oncolytic virus therapy for solid tumors. Breast cancer is among the second most common cancers to be diagnosed worldwide, and existing treatments are ineffective for curing metastatic breast cancer, which is frequently accompanied by significant side effects that drastically reduce the quality of life for patients. Oncolytic viral therapy has become an effective method to combat several cancers, including breast cancer. 

[poojascmi]

India Immuno-Oncology Drugs Market Is Estimated To Witness High Growth Owing To Increasing Adoption of Immunotherapy

The India Immuno-Oncology Drugs Market is estimated to be valued at US$265 Mn in 2022 and is expected to exhibit a CAGR of 13.1% over the forecast period of 2021-2028, as highlighted in a new report published by Coherent Market Insights. Market Overview: The India Immuno-Oncology Drugs Market refers to the use of immunotherapy drugs for the treatment of various types of cancer. These drugs work by stimulating the body's immune system to recognize and attack cancer cells. The market is driven by the increasing adoption of immunotherapy drugs due to their effectiveness in treating cancer, especially in advanced stages. Immuno-oncology drugs offer advantages such as targeted therapy, reduced side effects compared to traditional chemotherapy, and improved survival rates. The need for these products arises from the growing prevalence of cancer in India and the need for more effective treatment options. Market Key Trends: One key trend in the India Immuno-Oncology Drugs Market is the development of combination therapies. Researchers and pharmaceutical companies are exploring the potential of combining immunotherapy drugs with other treatment modalities, such as chemotherapy or targeted therapy, to enhance their efficacy. For example, the combination of immune checkpoint inhibitors with chemotherapy has shown promising results in clinical trials for various types of cancers. This trend is driven by the need for more effective treatment options and the desire to improve patient outcomes. PEST Analysis: Political: The political factors impacting the India Immuno-Oncology Drugs Market include government regulations and policies related to drug approvals, pricing, and reimbursement. The regulatory framework plays a crucial role in determining the accessibility and affordability of these drugs. Economic: Economic factors influencing the market include healthcare expenditure, insurance coverage, and affordability of immunotherapy drugs. The economic viability of these drugs is an important consideration for patients and healthcare providers. Social: Social factors such as awareness about cancer and its treatment options, patient preferences, and cultural beliefs impact the adoption of immunotherapy drugs. Education campaigns and initiatives to raise awareness about cancer care can drive market growth. Technological: Technological advancements in the field of immuno-oncology, such as the development of novel biomarkers and diagnostic tools, are driving the market. The integration of artificial intelligence and machine learning in cancer research and drug development also presents opportunities for market growth. Key Takeaways: 1: The India Immuno-Oncology Drugs Market Demand is expected to witness high growth, exhibiting a CAGR of 13.1% over the forecast period. This growth is attributed to increasing adoption of immunotherapy in cancer treatment, driven by its effectiveness and advantages over traditional chemotherapy. 2: The fastest growing and dominating region in the India Immuno-Oncology Drugs Market is India due to the high prevalence of cancer and improving healthcare infrastructure. The country has a large patient population seeking advanced treatment options. 3: Key players operating in the India Immuno-Oncology Drugs Market include Amgen Inc., AstraZeneca Plc, Bristol-Myers Squibb, Celgene Corporation, Eli Lilly and Company, Merck & Co., F. Hoffmann-La Roche AG, Johnson & Johnson, Novartis International AG, and AbbVie Inc. These companies invest heavily in research and development to bring innovative immunotherapy drugs to the market. In conclusion, the India Immuno-Oncology Drugs Market is poised to experience significant growth due to the increasing adoption of immunotherapy for cancer treatment. The development of combination therapies, along with favorable political, economic, social, and technological factors, further contribute to market expansion. Key players play a crucial role in driving innovation and bringing advanced therapies to cancer patients in India and globally.

[healthcaremarketfmi]

Brain Tumor Drugs Market Growth Factors, Restraints, Advancements and rising Trends Forecast 2023 to 2033

From 2023 to 2033, the market for drugs for brain tumors is anticipated to grow at a 9.2% CAGR. Market value is anticipated to reach US$ 2.65 billion in 2023 and US$ 6.30 billion in 2033.

The Brain Tumor Drugs Market is likely to grow from US$ 2.65 billion in 2023 to US$ 6.30 billion in 2033.

The Growing Use of Targeted Medicines is Putting a Damper on the Brain Tumor Medications Industry

The purpose of targeted cancer therapy is to kill malignant cells while leaving healthy cells alone. This therapy may be more effective than traditional chemotherapy and radiotherapy because it focuses on changes in the cell that are particular to cancer. Everolimus, for example, is a targeted medication that prevents cancer cells from growing and spreading.

Similarly, unlike chemical medications, which cannot block regeneration, Bevacizumab prevents cancer cell regeneration. The increased popularity of targeted therapy is likely to impact sales of conventional chemical brain tumor medications, limiting market growth over the projection period. Companies in the brain tumor market are concentrating on the application of nanotechnology for innovative treatment.

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Nanoparticles are utilized to deliver medications in combination straight to cancer cells or into tumors. This method has also resulted in a reduction in medicine dosage, increased shelf life, and reduced toxicity. A few nano drugs are proven to be effective in crossing the blood-brain barrier, which has been a substantial obstacle in the treatment of brain malignancies.

A brain tumor is an abnormal mass of tissue in which brain cells grow and replicate in an uncontrollable and fast manner. Brain cancers are classified into two types: primary brain tumors and metastatic brain tumors. Primary brain tumors are those that arise from the brain’s tissues or its surrounding tissues.

Pharmaceutical businesses have improved supply chain management, which has increased research and development and investment in quality control and manufacturing.

Key Takeaways

The brain tumor drugs market is expected to record a CAGR of 9.2% during the forecast period 2023 to 2033.

The primary drivers of the market are an increase in brain cancer prevalence, the presence of promising pipeline candidates, and an increased need for precision and customized treatment to drive market expansion.

North America dominated the brain tumor drugs market.

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Key Development in the Brain Tumor Drugs Market

April 2021 – MindMed and Nextage Therapeutics signed a Memorandum of Understanding (MOU) to maximize the administration of selected psychedelic drug candidates using Nextage’s unique Brain Targeting Liposome System (BTLS) delivery technology.

March 2021 – Roche and GenMark Diagnostics signed a comprehensive merger agreement for Roche to entirely acquire GenMark for US$ 24.05 per share in an all-cash transaction.

September 2022 – F. Hoffmann-La Roche Ltd. announced an agreement to acquire Good Therapeutics. With this acquisition, the firm gains access to Good Therapeutic’s platform technology, which is relevant to a wide range of sectors such as cancer, autoimmune illnesses, metabolic disease, and pain management.

June 2022 – Novartis AG received the United States FDA approval for Tafinlar + Mekinist for the treatment of paediatric and adult patients with solid cancers containing the BRAF V600E mutation. BRAF mutations are responsible for tumor growth in over 20 different tumor types, including brain, thyroid, and others.

November 2021 – Pfizer Inc. purchased Trillium Therapeutics, a clinical-stage immuno-oncology startup focused on creating novel cancer medicines.

Key Segment

By Therapy:

Targeted Therapy

Chemotherapy

Immunotherapy

Others

By Indication:

Pituitary

Meningioma

Glioma

Others

By Distribution Channel:

Hospital Pharmacy

Retail & Online Pharmacy

[sanjay-chem]

Immunohistochemistry Market Size, Share, Demand, Growth & Trends by 2032

As per Future Market Insights' latest industry analysis, the immunohistochemistry market size is expected to be worth US$ 2.05 billion in 2022 and US$ 4.59 billion by 2032, with a quick CAGR of 8.4% between 2022 and 2032.

Adoption of immunohistochemistry is anticipated to increase as a result of the rise in healthcare spending and the spike in interest in living a higher quality life.

The immunohistochemistry market outlook is anticipated to expand due to the increase in chronic diseases. As value-based healthcare solutions are becoming more popular, it is anticipated that the demand for immunohistochemistry is likely to increase rapidly.

The immunohistochemistry market share is expected to increase due to an increase in patients with cancer, infectious diseases, and cardiovascular disorders, all of which use immunohistochemistry for diagnosis.

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The alarming rate at which infectious diseases are spreading presents a challenge for medical professionals in developing drugs for such unidentified diseases. The rise in demand for immunohistochemistry for such diseases is expected to drive immunohistochemistry market growth.

According to the International Diabetes Federation, 463 million people aged 20 to 79 worldwide have diabetes as of 2019, with that figure expected to rise to nearly 700 million by 2045.

Increased R&D in immunohistochemistry-based techniques is expected to drive immunohistochemistry market growth in the coming years.

Additionally, the adoption of immunohistochemistry is estimated to grow over the course of the projected period due to an increase in the incidence and prevalence of chronic diseases like cancer, where proteins are expected to play a significant role. Short-term expansion of the immunohistochemistry industry is expected to be constrained by unfavorable reimbursement regulations.

Key Takeaways from Market Study

Since     antibodies play such an important role in disease diagnosis and medication     testing, the antibodies segment dominated the immunochemistry market in     2021, accounting for more than 41% of global revenue.

The     diagnostics application sector accounted for approximately 70% of revenue     in 2021, and it is expected that this segment is projected to lead during     the forecast period.

In     2021, hospitals and diagnostic laboratories generated more than 71% of     total revenue, dominating the immunochemistry market.

North     America is likely to dominate the immunochemistry market in 2021,     accounting for more than 39% of global sales.

Asia     Pacific is expected to have the fastest CAGR during the forecast period.     This is largely due to global players increased geographic presence in     Asian markets.

"Increasing automation and machine learning deployment in immunohistochemistry (IHC), as well as the release of technologically enhanced IHC solutions, are expected to significantly drive the immunohistochemistry market share during the forecast period. Due to advancements in IHC methods, the demand for immunohistochemistry in disease diagnosis has increased significantly."- Future Market Insights Analyst.

Competitive Landscape

Key players in the immunohistochemistry market are developing cutting-edge products that are expected to drive immunohistochemistry market growth.

The introduction of these clinical diagnostic markers could help the immuno-oncology field advance early cancer medication development. The immunohistochemistry market is expected to expand at a faster rate during the forecast period due to R&D advancements.

The following companies are among the major players in the global immunohistochemistry market: Thermo Fisher Scientific Inc., F. Hoffmann-La Roche Ltd., Merck KGaA; Danaher Corporation; PerkinElmer, Inc., Bio-Rad Laboratories, Inc., Cell Signaling Technology, Inc., Bio SB; Abcam plc., Agilent Technologies, Inc.

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Key Segments

By Product:

 Primary      Antibodies

 Secondary      Antibodies

 Slide      Staining System

 Tissue      Microarrays

 Tissue      Processing Systems

 Slide      Scanners

 Others

 Histological      stains

 Blocking      Sera and Reagents

 Chromogenic      Substrates

 Fixation      Reagents

 Stabilizers

 Organic      Solvents

 Proteolytic      Enzymes

 Diluents

By Application:

 Cancer

 Infectious      Diseases

 Cardiovascular      Diseases

 Autoimmune      Diseases

 Diabetes      Mellitus

 Nephrological      Diseases

By End-use:

Hospitals     & Diagnostic Laboratories

Research     Institutes

Others

By Region:

North     America

Latin     America

Europe

Asia     Pacific

MEA

Recent Developments in Immunohistochemistry Market:

Roche's     VENTANA MMR RxDx companion diagnostic test was approved by the FDA in     August 2021 for solid tumours that lack the MMR pathway. The test     determines who is eligible for JEMPERLI, GSK's anti-PD1 immunotherapy.

Agilent     received a CE-IVD mark in Europe in August 2021 for its PD-L1 IHC 22C3     pharmDx assay for the identification of oesophageal cancer patients for     treatment with KEYTRUDA.

Biocare     Medical LLC introduced the ONCORE Pro, a fully automated in vitro     diagnostic benchtop system for In-situ Hybridization (ISH) and IHC     applications, in January 2021.

In     January 2021, Abcam and Shuwen Biotech (Shuwen) formed a strategic     partnership to develop and market Companion Diagnostics (CDx). According     to the agreement, Abcam will provide recombinant rabbit monoclonal     antibodies to Shuwen Biotech for additional immunohistochemistry.

[bhushans]

Global Breast Cancer Drug market: A Deep Dive into Key Drivers and Trends

The global Breast Cancer Drug market. According to a recent analysis, the market size is projected to be worth US$ 10,733.1 million in 2023. Between 2023 and 2033, the total demand for breast cancer medications is expected to expand at a Compound Annual Growth Rate (CAGR) of 1.1%, reaching approximately US$ 12,012.1 million by that time.

Breast cancer remains a significant healthcare challenge globally, with the disease's rising prevalence driving the demand for innovative treatments. Effective care of breast cancer necessitates early diagnosis and access to advanced therapies, highlighting the importance of continued innovation and development in the breast cancer drug market.

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Addressing Breast Cancer: A Market Focused on Innovation and Early Detection

The global breast cancer drug market is experiencing steady growth, driven by the continuous need for effective treatment options and the ongoing battle against this prevalent disease. Early detection remains a critical factor in managing breast cancer effectively.

Multiple Factors Shape Market Landscape:

Although growth is projected to be modest, several factors are influencing the breast cancer drug market:

Rising Prevalence: Unfortunately, the number of breast cancer diagnoses is expected to continue rising globally. This creates a larger patient population in need of treatment.

Novel Therapies: The development of innovative therapies, such as targeted drugs and immunotherapies, offers new treatment options and hope for improved patient outcomes.

Focus on Early Detection: Increased awareness campaigns and improved diagnostic tools contribute to earlier detection, allowing for more effective treatment interventions.

Key Takeaways:

The global breast cancer drug market is projected to reach US$12,012.1 million by 2033, reflecting a rise from US$10,733.1 million in 2023.

This growth is expected at a moderate compound annual growth rate (CAGR) of 1.1% throughout the forecast period.

The rising prevalence of breast cancer and the development of novel therapies are key drivers for market expansion.

Competitive Landscape:

In August 2021, Pfizer Inc. and Trillium Therapeutics Inc. entered into a definitive agreement under which Pfizer will acquire Trillium, a clinical-stage immuno-oncology company developing innovative therapies for the treatment of cancer. Under the terms of the agreement, Pfizer will acquire all outstanding shares of Trillium not already owned by Pfizer for an implied equity value of $2.26 billion, or $18.50 per share, in cash.

In June 2022, Novartis announced new overall survival (OS) and quality of life (QoL) analyses which evaluated Kisqali® (ribociclib) plus endocrine therapy for patients with hormone receptor-positive/human epidermal growth factor receptor-negative (HR+/HER2-) advanced or metastatic breast cancer.

Key Companies Profiled:

F. Hoffmann-La Roche Ltd

Pfizer Inc.

AstraZeneca

Novartis International AG

Achieve Life Science

Bristol-Myers Squibb

Eisai Co. Ltd

AbbVie

Eli Lilly & Company

Celgene Corporation

Merck & Co.

Amgen Plc.

Celldex Therapeutics

Biocon Genzyme Corporation

Key Segments Covered in the Breast Cancer Drug Industry Analysis:

By Drug Class:

SERM (Selective Estrogen-Receptor Modulators)-based

Aromatase Inhibitors-based

Biologic Response Modifiers-based

Other Hormonal Therapies-based

By Distribution Channel:

Hospital Pharmacies

Pharmacies

Drug Stores

By Region:

North America

Latin America

Europe

Asia Pacific

Middle East & Africa

[impossibledeanmakerwombat]

Biosimulation Market Current and Future Trends, Leading Players, Industry Segments and Regional Forecast to 2023 to 2032 | Says FMI

The Global Biosimulation Market according to a recent market study by Future Market Insights, was valued at US$ 2.6 billion in 2021 and is predicted to grow to US$ 20.9 billion by 2032. According to the report’s conclusions, biosimulation software will continue to be crucial for the market because it will account for the majority of sales. Software biosimulation will give the trials better and more effective findings, and there are many different types of software accessible for different types of research and application. From 2015 through 2021, the software segment’s revenue increased at a CAGR of 14.3%.

Revenue through Drug Development to Continue being growth Axis For Biosimulation Market

Pharmaceutical companies use biosimulation for drug development.  During a drug, development process biosimulation helps to identify the possible effects that the drug can have on a patient. The market through the drug development segment recorded a CAGR of 16.3% during 2015-2021.

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Biosimulation Market: Competition Insights

The key companies operating in the biosimulation market include Certara, Dassault Systemes, Advanced Chemistry Development, Simulation Plus Inc., Schrodinger, Inc., Chemical Computing Group, Physiomics Plc, Rosa & Co. LLC, BioSimulation Consulting Inc., Genedata AG, Instem Group of Companies, PPD, Inc., Insilico Biotechnology AG,  Rhenovia Pharma, LeadInvent Technologies, Nuventra Pharma, and In Silico  Biosciences.

Some of the recent developments by key providers of biosimulation are as follows:

In June 2022, Certara announced its new version of Biosimulation software for the progress of Novel Biologics. The new version includes Immunogenicity (IG), Immuno-Oncology (IO), and Vaccine simulators to understand and predict how drugs work and point out the key questions in the development of novel biologic therapies.

In June 2022, Genedata AG announced that Syros Pharmaceuticals has chosen Genedata AG’s Genedata Profiler as its data integration and investigative platform to accelerate its translational research strategy.

In March 2022, Advanced Chemistry labs announced that Pharmaron Inc. has chosen its NMR processing and interpretation software.

In March 2022, Simulation Plus, Inc. released its Membrane Plus 3.0 software. The new software includes improved data handling and simulation performance for in vitro-in vivo for extrapolation (IVIVE) for permeability, skin penetration, and release assay systems.

In February 2022, the US Food and Drug Administration (FDA) approved the license for Certara’s Immunogenicity (IG) stimulator to research and assess immunogenicity in protein-based remedies.

In February 2022, Physiomics Plc updated a new agreement with ValiRx plc. According to the new agreement, ValiRx will be able to use Physiomics Plc’s latest version of its Virtual Tumour technology. Physiomics Plc will also help ValiRx in modeling the use of VAL201 peptide in endometriosis (VAL301) and Coronavirus (BC201).

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More Insights Available

Future Market Insights, in its new offering, presents an unbiased analysis of the Biosimulation Market, presenting historical market data (2017-2021) and forecast statistics for the period of 2022-2032.

The study reveals essential insights by Product Type (Services (In-house services, Contract services), Software), by Deployment mode (Drug Development, Drug Discovery, Other Applications), by End-use (Pharmaceutical & Biotechnology Companies, CROs, Regulatory Authorities, Academic Research Institutions), across five regions (North America, Latin America, Europe, Asia Pacific, and Middle East & Africa).

Key Segments Covered in Biosimulation Industry Survey

Biosimulation Market by Product Type:

Services

In-house services

Contract services

Software

Biosimulation Market by Deployment Mode:

Drug Development

Drug Discovery

Other Applications

Biosimulation Market by End-use:

Pharmaceutical &Biotechnology Companies

CROs

Regulatory Authorities

Academic Research Instituitons

Full Report @ https://www.futuremarketinsights.com/reports/biosimulation-market

[rohit890]

Immuno-Oncology Assay Market Competition from Opponents, Dynamics, Demand and Risk to 20231

Market Overview

The global immune-oncology assay market was valued at USD 4.2 billion in 2021 and it is anticipated to grow further up to USD 14.1 billion by 2031, at a CAGR of 12.9% during the forecast period.

One kind of immunoassay that is mostly used to diagnose cancer is the immuno-oncology assay. It is a process that profiles different analytes by simultaneously detecting and measuring them, including proteins, biomolecules, growth factors, cytokines, and chemokines. This method primarily targets and eliminates cancer cells using the body’s natural defensive mechanism. This assay is used for in vitro research to investigate the complex tumor microenvironment, the dynamic interactions between cancer cells and immune cells, and the perception of immunoreactivity in a variety of cell-based assays to determine the mode of action.

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Market Dynamics

As a multi-stage carcinogenesis process involving numerous molecular pathway events, cancer is a complex illness that arises. So, the diagnosis, prognosis, and treatment of cancer are all accompanied with a number of challenges. In this aspect, a single marker is not useful due to the complexity of cancer. Each cancer also differs from other cancer kinds in terms of its molecular profile. As a result, the use of immuno-oncology assays has proved crucial for comprehending cancer signatures and creating individualized treatments. Over the past few years, cancer has become more commonplace across the globe. In 2018, there were 9.6 million fatalities due to cancer, which has overtaken all other causes of mortality in the world. GLOBOCAN predicts that by 2040, there would be over 30 million new instances of cancer, up from 18 million in 2018. Africa, Asia, Central and South America account for more than 60% of all new cancer cases, and these regions also account for 70% of all cancer-related fatalities worldwide. As a result, there is a need for considerable research to be done for cancer detection and therapy, and immuno-oncology assays play a significant role in this study.

The discovery, development, and validation of biomarkers demand large capital expenditures. Additionally, diagnostic manufacturers have major financial difficulties as a result of the high drug attrition in clinical trials (with about 30% of medications failing in Phase III). In order for manufacturers to receive regulatory permission for in vitro diagnostics (IVD), Phase III clinical trials that rely on reliable biomarker tests must be successful. The cost of conducting clinical trials and meeting onerous regulatory criteria severely limits innovation and makes it difficult for small businesses to develop biomarkers. As a result, in addition to the high capital expenditures, the low cost-benefit ratio is impeding the expansion of the market for immuno-oncology assays for biomarker identification.

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The key players studied in the market are Thermo Fisher Scientific, Inc. (US), F. Hoffmann-La Roche Ltd. (Switzerland), Agilent Technologies, Inc. (US), Illumina, Inc. (US), NanoString Technologies, Inc. (US), Sartorius AG (Germany), HTG Molecular Diagnostics, Inc. (US), QIAGEN N.V. (Netherlands), Merck Millipore (US), PerkinElmer, Inc. (US), Abbott Laboratories, Inc. (US), Guardant Health, Inc. (US), and bioMérieux SA (France) among others.

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Global Insight Services (GIS) is a leading multi-industry market research firm headquartered in Delaware, US. We are committed to providing our clients with highest quality data, analysis, and tools to meet all their market research needs. With GIS, you can be assured of the quality of the deliverables, robust & transparent research methodology, and superior service.

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[aartichede08]

Future Of North American Oncology Drugs Market: Size, Share, And Forecast 2019–2028

Cancer research is advancing rapidly and new medicines in development take many innovative approaches to fighting the disease. There has been tremendous innovation over the past decade with the emergence of new drugs with very promising efficacy, such as, immunotherapy, along with increasing adoption of precision medicine technologies including companion diagnostics and targeted therapy, as well as advanced monitoring techniques such as liquid biopsy. New treatment options have become available in the past five years, and the surge of innovation is expected to continue due to a robust pipeline of drugs in clinical development by a large and diverse group of pharmaceutical companies. Over 20 tumour types are being treated with one or more of the 70 new cancer treatments that have been launched over the past five years. Furthermore, the impact of these new medicines on patient care is exemplified by the case of the two PD-1 immuno-oncology drugs, whose rapid uptake reflect their remarkable clinical profile and successive expansion of indications.

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NORTH AMERICAN ONCOLOGY DRUGS MARKET OUTLOOK

The United States has made significant improvements in cancer care, the death rate from cancer in the US has declined steadily over the past 25 years, according to annual statistics reporting from the American Cancer Society. As of 2016, the cancer death rate for men and women combined had fallen 27% from its peak in 1991. This decline translates to about 1.5% per year and more than 2.6 million deaths avoided between 1991 and 2016, it is attributed by the growing number of drugs and technologies available to patients. The direct costs of cancer represent approximately 5% of total direct US health care expenditures. Besides, very expensive cancer treatments such as the new immunotherapies for cancer are more widely available in America than in countries with national healthcare where there are restrictions based on cost/benefit and budget caps.

Moreover, according to the American Cancer Society, in men, the most common cancers diagnosed are prostate, lung, and colorectal cancers. Together, they account for 42% of all cases in men, with prostate cancer alone accounting for nearly 1 in 5 new cases.

NORTH AMERICAN ONCOLOGY DRUGS MARKET SEGMENTAL OVERVIEW

The report analyses the North America oncology drugs market based on therapeutic modules, cancer type and country.

NORTH AMERICAN ONCOLOGY DRUGS MARKET BY THERAPEUTIC MODULES

Based on the therapeutic modules, the oncology drugs market is segmented into chemotherapy, targeted therapy, immunotherapy, hormonal therapy and others. The other therapeutic modules consist of radiation therapy, stem cell transplant, precision medicine among others. Immunotherapy is expected to dominate the North America market due to its high efficacy and less side effects. Monoclonal antibodies such as trastuzumab, bevacizumab and rituximab are potential immunotherapeutic agents that have achieved magnanimous sales. Moreover, over the past few years, targeted cancer therapies have gained significant attention due to their tumour cell specific action in protecting healthy cells from the toxic effects of oncology drugs.

NORTH AMERICAN ONCOLOGY DRUGS MARKET BY CANCER TYPE

By various cancer types, the North America oncology drugs market is segmented into blood cancer, breast cancer, gastrointestinal cancer, prostate cancer, lung cancer, skin cancer and others. Other cancer types majorly include kidney cancer, head & neck cancers, lip cancer, bladder cancer among others. With rapid population growth and aging, the rising prominence of cancer as a leading cause of death partly reflects marked declines in mortality rates of stroke and coronary heart disease, relative to cancer, in many countries.

NORTH AMERICAN ONCOLOGY DRUGS MARKET BY COUNTRY

Various countries included in the North America oncology drugs market are United States, Canada and Mexico. The United States majorly contributed to the oncology drugs market in 2018. Furthermore, Canada is anticipated to be second largest market in oncology drug market. The U.S. region houses companies engaged in the development of oncology drugs. Additionally, the disposable incomes of consumers and health insurance cover for life-threatening diseases in U.S. are very high which increases the affordability of cancer treatment. In recent years, US Food and Drug Administration (USFDA) has taken initiatives to support the growth of oncology drugs market by providing pre-market approval to the drugs, which are in the clinical phase; thus, accelerating the clinical development.

NORTH AMERICAN ONCOLOGY DRUGS MARKET KEY PLAYERS

North America oncology drugs market is led by companies such as, Roche Holding AG (Switzerland), Amgen Inc. (United States), Takeda Pharmaceutical Company Limited (Japan), Bayer AG (Germany), Boehringer Ingelheim GmbH (Germany), Bristol-Myers Squibb Company (United States), Celgene Corporation (United States), Eli Lilly and Company (United States), Johnson & Johnson (United States), Merck & Co., Inc. (United States), Novartis AG (Switzerland), Pfizer Inc. (United States), Sanofi (France) and Teva Pharmaceutical Industries Limited (Israel). In November 2018, Bristol-Myers Squibb Company the U.S. Food and Drug Administration (FDA) approval of Empliciti (elotuzumab) injection for intravenous use in combination with pomalidomide and dexamethasone (EPd) for the treatment of adult patients with multiple myeloma who have received at least two prior therapies, including lenalidomide and a proteasome inhibitor.

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