#LabOnAChip

[globalinsightblog]

Digital Microfluidic Chips: Growth from $1.2B to $3.8B by 2034 💧

Digital Microfluidic Chips Market is set to expand from $1.2 billion in 2024 to $3.8 billion by 2034, growing at a CAGR of 12.2%. These cutting-edge chips, which control microfluidic droplets via electronic signals, are transforming diagnostics, drug discovery, and lab automation, enabling faster, more precise, and cost-effective analysis.

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Key Market Trends & Drivers

🔹 Lab-on-a-Chip Technology Leads: Enabling rapid, miniaturized diagnostics for real-time testing. 🔹 Point-of-Care Testing Growth: Rising demand for portable, on-site diagnostic solutions. 🔹 Drug Discovery & Biotechnology Boom: Increasing adoption for high-throughput screening & molecular analysis. 🔹 AI & IoT Integration: Enhancing automation, efficiency, and remote monitoring capabilities. 🔹 Advancements in MEMS & Microarrays: Expanding applications in genomics, proteomics, and precision medicine.

Regional Market Insights

🌎 North America dominates, driven by cutting-edge research & healthcare infrastructure. 🌍 Europe follows, with strong investments in biotech & medtech R&D. 🌏 Asia-Pacific emerges as a key growth hub, fueled by government initiatives & rapid industrialization. 🌍 Latin America & the Middle East are adopting microfluidic tech in diagnostics & environmental monitoring.

Market Segmentation Overview

🔹 Type: Electrowetting, Magnetic, Dielectrophoretic 🔹 Technology: Integrated Circuit, MEMS, Microarray 🔹 Applications: Diagnostics, Drug Delivery, Cell Culture, Genomics, Proteomics 🔹 Materials: Glass, Silicon, Polymer 🔹 End Users: Healthcare, Biotech, Pharma, Research Labs

📈 In 2024, the market saw 320 million units, with healthcare leading (45%), followed by research labs (30%) and consumer electronics (25%). Illumina, Bio-Rad, & Advanced Liquid Logic dominate, pioneering innovations in microfluidic automation & precision diagnostics.

As AI, automation, and bioinformatics reshape digital microfluidics, this market is poised to revolutionize disease detection, drug discovery, and next-gen healthcare solutions! 💡🔍

#Microfluidics #LabOnAChip #BioTech #PointOfCare #Diagnostics #HealthcareInnovation #DrugDiscovery #BiotechRevolution #MEMS #AIinHealthcare #WearableTech #PersonalizedMedicine #Genomics #Proteomics #MedicalDevices #Biosensors #SmartDiagnostics #Microarray #PharmaTech #PrecisionMedicine #NextGenHealthcare #DigitalBiomarkers #TechInMedicine #Nanotechnology #SmartLabs #R&D

[lovelypol]

Tech in Labs: Digital Microfluidic Chips Market to Expand to $3.8B by 2034

Digital Microfluidic Chips Market is advancing rapidly, revolutionizing the way small fluid volumes are controlled using electronic signals. These chips are pivotal in diagnostics, drug discovery, and environmental monitoring, offering enhanced precision and efficiency. Their role in lab-on-a-chip technologies, point-of-care testing, and automated analytical devices is shaping the future of fluid analysis with miniaturized and automated solutions.

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The healthcare sector leads the market, capturing a 45% share due to the chips’ crucial role in diagnostic testing and drug delivery systems. These chips provide real-time, accurate results, improving patient care and medical outcomes. The biotechnology and pharmaceutical industries also play a significant role, leveraging digital microfluidic chips for drug discovery and development processes. The demand for these technologies continues to rise, as they enable more efficient, cost-effective research and development.

In terms of geography, North America dominates the market, with the United States leading due to its advanced healthcare infrastructure and high R&D investments. Europe follows closely, with Germany excelling thanks to its industrial base and commitment to technological innovation. The market is projected to grow significantly, from 320 million units in 2023 to 580 million units by 2033, with a 15% annual growth.

Key players like Illumina, Inc., Bio-Rad Laboratories, and Advanced Liquid Logic are pushing the boundaries of innovation, especially in next-gen sequencing and precision diagnostics. The integration of AI and machine learning in these technologies promises even greater efficiency and customization in fluid analysis, propelling the market forward.

#DigitalMicrofluidics #LabOnAChip #FluidControl #Diagnostics #DrugDiscovery #PointOfCare #Biotechnology #PharmaceuticalInnovation #Miniaturization #TechInHealthcare #HealthTech #PrecisionMedicine #AIInDiagnostics #MedicalTechnology #R&DInnovation

[fumpkins]

Faster, More Precise Lab-On-A-Chip Holds Promise of Early Cancer Diagnosis

Squeezing light into nano-size volumes is enabled by surface plasmon resonance, a phenomenon that causes molecules to be trapped near the film, making them available for study under powerful microscopes. (Justus Ndukaife/Vanderbilt University)

An award-winning Vanderbilt University researcher used plasmonics to develop a new kind of nanotweezers that can rapidly trap and detect molecules, viruses and DNA – a device transformative for medicine that also has color printing applications.

Assistant Professor of Electrical Engineering Justus Ndukaife (Steve Green/Vanderbilt University)

Assistant Professor of Electrical Engineering Justus Ndukaife and his Purdue University collaborators poked holes in gold film smaller than the wavelength of light. Squeezing light into such small volumes is enabled by surface plasmon resonance, a phenomenon that causes molecules to be trapped near the film, making them available for study under powerful microscopes.

The result is what’s commonly known as a lab-on-a-chip – a new way of detecting and diagnosing cancer, viruses or any number of ailments.

Ndukaife’s nanotweezers require less laser power, have more potential to trap and stabilize molecules and allow for higher resolution than previous versions used for lab-on-a-chip applications.

He said they also have the potential for using broadband wavelength light source to assemble gold and silicon nanoparticles, which could have applications for permanent, non-fading color printing.

His results recently were published in the journal ACS Nano. The work was made possible by the National Science Foundation’s Materials Research Science and Engineering Centers grant DMR-1120923.

Ndukaife, who won the 2017 Chorafas Foundation Prize in Physics for his nanotweezers work, also recently was selected for the Carnegie African Diaspora Fellowship Program. He will work with the University of Nigeria, Nsukka on development and testing of a lab-on-a-chip device for isolation and concentration of e-coli bacteria.

Ndukaife’s project is part of a broader initiative that will pair 55 CADFP scholars with one of 43 higher education institutions and collaborators in Ghana, Kenya, Nigeria, South Africa, Tanzania and Uganda to work together on curriculum co-development, research, graduate teaching, training and mentoring in the coming months.

The fellowships cover all expenses for African-born scholars to work with host universities across the continent, helping people there and building relationships with U.S. institutions.

Source : Vanderbilt University

New post published on: https://www.livescience.tech/2018/06/27/faster-more-precise-lab-on-a-chip-holds-promise-of-early-cancer-diagnosis/

[slimlastforskolins]

Lab-on-a-chip may help identify new treatments for liver disease -- ScienceDaily

Lab-on-a-chip may help identify new treatments for liver disease — ScienceDaily

Non-alcoholic fatty liver disease (NAFLD) — the accumulation of liver fat in people who drink little or no alcohol — is increasingly common around the world, and in the United States, it affects between 30 and 40 percent of adults. Currently, there are no approved drugs for the treatment of NAFLD, which is predicted to soon become the main cause of chronic liver problems and the need for liver…

[my-daily-health-tips-world-blog]

Twisters Inside a Lab-on-a-Chip Trap Viruses, DNA, Biomolecules

Twisters Inside a Lab-on-a-Chip Trap Viruses, DNA, Biomolecules

Twisters Inside a Lab-on-a-Chip Trap Viruses, DNA, Biomolecules

At Purdue University engineers have developed a new type of optical nanotweezers that can be used to grab onto and inspect viruses, DNA strings, and other important biomolecules.

The innovative lab-on-a-chip device relies on a “nanostructured plasmonic metafilm” created out of a very thin gold sheet with nano-scale holes drilled…

[superbesthealthtipsindailyl-blog]

Twisters Inside a Lab-on-a-Chip Trap Viruses, DNA, Biomolecules

Twisters Inside a Lab-on-a-Chip Trap Viruses, DNA, Biomolecules

Twisters Inside a Lab-on-a-Chip Trap Viruses, DNA, Biomolecules

At Purdue University engineers have developed a new type of optical nanotweezers that can be used to grab onto and inspect viruses, DNA strings, and other important biomolecules.

The innovative lab-on-a-chip device relies on a “nanostructured plasmonic metafilm” created out of a very thin gold sheet with nano-scale holes drilled…

[royalvoxpost]

#PrecisionMedicine: new microfluidic brain cancer chip could facilitate the study of in vitro cancer models. The device generates tumor spheroids and characterizes the response of tumor cells to various concentrations and combinations of drugs https://t.co/q82QJGyRmC #LabOnAChip https://t.co/xh4L9R11ta

#PrecisionMedicine: new microfluidic brain cancer chip could facilitate the study of in vitro cancer models. The device generates tumor spheroids and characterizes the response of tumor cells to various concentrations and combinations of drugs https://t.co/q82QJGyRmC #LabOnAChip pic.twitter.com/xh4L9R11ta

— The Royal Vox Post (@RoyalVoxPost) January 16, 2020

via Twitter https://twitter.com/RoyalVoxPost January 16, 2020 at 09:53PM

[fumpkins]

How to Make a Lab-On-A-Chip Clear and Biocompatible

. . . .

Microfluidic gadgets can take basic medical laboratory treatments and condense each down to a microchip that balances on top of a water bottle cover. A group from Michigan Technological University, studying chemical engineering, electrical engineering and products science, improve the style of microfluidic gadgets to be transparent to observe their inner operations. Using hair-thin tunnels and similarly small electrodes, these gadgets funnel fluids through an electrical present to sort cells, discover illness and run diagnostic tests.

The issue is that biological samples are not inert– they’re charged and all set to communicate. When fluids can be found in contact with microdevice electrodes, surges can occur. Tiny ones. But blowing up red cell– brought on by an ion imbalance that bursts cell membranes in a procedure called lysis– beat the point of screening blood glucose levels or blood type. In other tests, like those for cancer or contagious illness, tinkering the sample chemistry can lead to faIse negatives or incorrect positives. Interactions in between samples and electrodes, called Faradaic responses, can be an undesirable adverse effects in microfluidics.

To protect the stability of samples and preserve a clear surface area to observe what’s going on inside the gadget, Michigan Tech engineers information how thin hafnium oxide layers imitate a cell phone screen protector for microdevices. Their work was just recently released in ThinSolid Films( DOI: 10.1016/ j.tsf.201807024) and a video of one gadget demonstrates how the protective layer works.

Designinga Lab- on-a- chip

JeanaCollins, speaker of chemical engineering, studied microfluidics for her doctoral research study at Michigan Tech and is the very first author on the paper. She discusses how the lab-on-a- chip usages a procedure called dielectrophoresis.

“The dielectrophoretic response is a movement,” she states. “And how can you tell it moved? By watching it move.”

Collins goes on to discuss that a non-uniform electrical field from the electrodes communicates with the charge on the particles or cells in a sample, triggering them to move. Many biological lab-on-a- chip gadgets depend on this type of electrical action.

“As chemical engineers, we deal more with the fluidics side,”Collins states, including that the electronic devices are likewise crucial and a blood sugar meter is a prime example. “You’ve got the blood—that’s your fluid—and it goes in, you have a test done, then you get a digital readout. So it’s a combination of fluidics and electronics.”

Hafnium oxide coats the left gadget and supplies both sample defense and optical openness to aid enhance the research study of microfluidic medical gadgets. Credit: Sanaz Habibi

Even though a advertised lab-on-a- chip like a glucose meter is covered, Collins and other engineers require to see what’s going on to get a clear photo under a microscopic lense. That’s why hafnium oxide, which leaves just a minor shade, works in their microdevice style advancement.

Also, the technology does not use to a single gadget. Because of its simpleness, the hafnium oxide layer deals with a variety of electrode styles, keeps a constant dielectric constant of 20.32and is hemocompatible– that is, it lessens the Faradaic responses that can trigger cell lysis so less red cells blow up when they come near the electrodes.

Collinsand her group evaluated 3 various densities of hafnium oxide–58 nanometers, 127 nanometers and 239 nanometers. They discovered that depending upon the deposition time– 6.5 minutes, 13 minutes and 20 minutes– the grain size and structure can be fine-tuned for the requirements of particular gadgets. The just prospective concern would be for fluorescence-based microdevices since the hafnium oxide does disrupt particular wavelengths. However, the layer’s optical openness makes it a excellent option for numerous biological lab-on-a- chip tests.

Clear,Biocompatible and Interdisciplinary

Collins explains that the job’s success is straight connected to the group’s complementary abilities. By combining chemical engineers, electrical engineers, products researchers and the Michigan Tech MicrofabricationShared User Facility, they were able to press the limits of all their fields.

“Microdevice design has tended toward increasing levels of complexity; each level of complexity increases probability of failure,” states AdrienneMinerick, dean of the School of Technology, teacher of chemical engineering and Collins’ doctoral advisor. “Simple solutions—while challenging to find—can provide robust, failure-resistant solutions for a wide range of applications. We explored numerous polymeric and inorganic films.”

“It took an interdisciplinary team to reveal the chemical structure and behaviors to provide an elegant option for wide ranging lab-on-a chip problems.”

AdrienneMinerick

The other co-authors consist of Hector Moncada Hernandez, Sanaz Habibi, Zhichao Wang from the Department of Chemical Engineering and Chito Kendrick, Nupur Bihari, Paul Bergstrom from the Department of Electrical and Computer Engineering.

Source: MichiganTechnological University

New post published on: https://livescience.tech/2018/10/06/how-to-make-a-lab-on-a-chip-clear-and-biocompatible/

[space4international]

A tweet

Excellent #labonachip work @MIMETAS_3D We hope #animalwelfare groups such as #oxfordanimalethics get supporting such tech with great potential to accomplish the #3Rs yet reveal de-novo #angiogenesis inhibitors + stimulants https://t.co/KzFqwMcOle

— space4 (@EarthMoonMars) January 29, 2019

[snehajamadade]

Global Lab-on-a-chip (LOC) Market 2018 Size, Share, Growth, Trends, Type, Application, Analysis and Forecast by 2025 – ABNewswire – Press Release Distribution Service – Paid Press Release Distribution Newswire

[royalvoxpost]

#Nanobiotechnology: researchers have designed a microphysiological platform mimicking the human blood–brain-barrier. The device could help develop realistic models of neuroinflammation and reactive gliosis - https://t.co/PDlfNLplVZ #LabOnaChip #Neuroscience #Biotech https://t.co/kyAa0HoVIz

#Nanobiotechnology: researchers have designed a microphysiological platform mimicking the human blood–brain-barrier. The device could help develop realistic models of neuroinflammation and reactive gliosis - https://t.co/PDlfNLplVZ#LabOnaChip #Neuroscience #Biotech pic.twitter.com/kyAa0HoVIz

— The Royal Vox Post (@RoyalVoxPost) January 10, 2020

via Twitter https://twitter.com/RoyalVoxPost January 10, 2020 at 06:01PM

[clarencegamboa-blog]

via Twitter https://twitter.com/oneclipsesci

[securitynewswire]

Integrated labonachip uses smartphone to quickly detect multiple pathogens EurekAlert press release

SNPX.com : http://dlvr.it/Q0XnsQ

[fumpkins]

How to Make a Lab-On-A-Chip Clear and Biocompatible

. . . .

Microfluidic gadgets can take basic medical laboratory treatments and condense each down to a microchip that balances on top of a water bottle cover. A group from Michigan Technological University, studying chemical engineering, electrical engineering and products science, improve the style of microfluidic gadgets to be transparent to observe their inner operations. Using hair-thin tunnels and similarly small electrodes, these gadgets funnel fluids through an electrical present to sort cells, discover illness and run diagnostic tests.

The issue is that biological samples are not inert– they’re charged and all set to communicate. When fluids can be found in contact with microdevice electrodes, surges can occur. Tiny ones. But blowing up red cell– brought on by an ion imbalance that bursts cell membranes in a procedure called lysis– beat the point of screening blood glucose levels or blood type. In other tests, like those for cancer or contagious illness, tinkering the sample chemistry can lead to faIse negatives or incorrect positives. Interactions in between samples and electrodes, called Faradaic responses, can be an undesirable adverse effects in microfluidics.

To protect the stability of samples and preserve a clear surface area to observe what’s going on inside the gadget, Michigan Tech engineers information how thin hafnium oxide layers imitate a cell phone screen protector for microdevices. Their work was just recently released in ThinSolid Films( DOI: 10.1016/ j.tsf.201807024) and a video of one gadget demonstrates how the protective layer works.

Designinga Lab- on-a- chip

JeanaCollins, speaker of chemical engineering, studied microfluidics for her doctoral research study at Michigan Tech and is the very first author on the paper. She discusses how the lab-on-a- chip usages a procedure called dielectrophoresis.

“The dielectrophoretic response is a movement,” she states. “And how can you tell it moved? By watching it move.”

Collins goes on to discuss that a non-uniform electrical field from the electrodes communicates with the charge on the particles or cells in a sample, triggering them to move. Many biological lab-on-a- chip gadgets depend on this type of electrical action.

“As chemical engineers, we deal more with the fluidics side,”Collins states, including that the electronic devices are likewise crucial and a blood sugar meter is a prime example. “You’ve got the blood—that’s your fluid—and it goes in, you have a test done, then you get a digital readout. So it’s a combination of fluidics and electronics.”

Hafnium oxide coats the left gadget and supplies both sample defense and optical openness to aid enhance the research study of microfluidic medical gadgets. Credit: Sanaz Habibi

Even though a advertised lab-on-a- chip like a glucose meter is covered, Collins and other engineers require to see what’s going on to get a clear photo under a microscopic lense. That’s why hafnium oxide, which leaves just a minor shade, works in their microdevice style advancement.

Also, the technology does not use to a single gadget. Because of its simpleness, the hafnium oxide layer deals with a variety of electrode styles, keeps a constant dielectric constant of 20.32and is hemocompatible– that is, it lessens the Faradaic responses that can trigger cell lysis so less red cells blow up when they come near the electrodes.

Collinsand her group evaluated 3 various densities of hafnium oxide–58 nanometers, 127 nanometers and 239 nanometers. They discovered that depending upon the deposition time– 6.5 minutes, 13 minutes and 20 minutes– the grain size and structure can be fine-tuned for the requirements of particular gadgets. The just prospective concern would be for fluorescence-based microdevices since the hafnium oxide does disrupt particular wavelengths. However, the layer’s optical openness makes it a excellent option for numerous biological lab-on-a- chip tests.

Clear,Biocompatible and Interdisciplinary

Collins explains that the job’s success is straight connected to the group’s complementary abilities. By combining chemical engineers, electrical engineers, products researchers and the Michigan Tech MicrofabricationShared User Facility, they were able to press the limits of all their fields.

“Microdevice design has tended toward increasing levels of complexity; each level of complexity increases probability of failure,” states AdrienneMinerick, dean of the School of Technology, teacher of chemical engineering and Collins’ doctoral advisor. “Simple solutions—while challenging to find—can provide robust, failure-resistant solutions for a wide range of applications. We explored numerous polymeric and inorganic films.”

“It took an interdisciplinary team to reveal the chemical structure and behaviors to provide an elegant option for wide ranging lab-on-a chip problems.”

AdrienneMinerick

The other co-authors consist of Hector Moncada Hernandez, Sanaz Habibi, Zhichao Wang from the Department of Chemical Engineering and Chito Kendrick, Nupur Bihari, Paul Bergstrom from the Department of Electrical and Computer Engineering.

Source: MichiganTechnological University

New post published on: https://www.livescience.tech/2018/10/06/how-to-make-a-lab-on-a-chip-clear-and-biocompatible/