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#Leigh Syndrome Treatment Market
gauricmi · 5 months
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Global Leigh Syndrome Treatment market is Estimated to Witness High Growth Owing to Increasing Disease Awareness
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The global Leigh syndrome treatment market is expected to exhibit significant growth due to rising prevalence of the rare genetic disorder. Leigh syndrome is a rare and aggressive neurological disorder caused by mutations in mitochondrial DNA or nuclear genes involved in mitochondrial biogenesis and respiration. The characteristic symptoms of Leigh syndrome include developmental delay, loss of motor skills, weakness, vision problems, and respiratory issues. Currently, there is no definitive treatment for Leigh syndrome. Treatments mainly focus on managing symptoms by targeting the underlying cause. Therapies primarily include vitamin and nutritional supplements, physical and occupational therapy, and medications targeting respiratory and neurological complications.
The global Leigh syndrome treatment market is estimated to be valued at US$ 272.9 million  in 2024 and is expected to exhibit a CAGR of 6.7% over the forecast period from 2024 to 2031. Key Takeaways Key players operating in the Global Leigh Syndrome Treatment Market Growth are Abliva AB, PTC Therapeutics, VAKS Pharma, MITOCH, Medley Pharmaceuticals Ltd., Khondrion BV, OMEICOS THERAPEUTICS GMBH. , Edison Pharmaceuticals, Inc. , Dainippon Sumitomo Pharma Co. Ltd., Taysha GTx, PicnicHealth (AllStripes), Takeda Pharmaceutical Company , Biogen, Ionis Pharmaceuticals, Inc., Sarepta Therapeutics, Inc., and MECOSON LABS PRIVATE LIMITED. The global Leigh syndrome treatment market is expected to witness lucrative growth opportunities due to increasing research funding for rare disease drug development and growing orphan drug designations. Furthermore, advancements in understanding the genetics and underlying mechanisms of Leigh syndrome are likely to aid the development of novel targeted treatment options. Key players are actively focusing on expanding their geographical presence through collaborations and partnerships with regional healthcare providers to cater to the growing patient population worldwide. For instance, in 2021, Khondrion partnered with Taysha Gene Therapies to accelerate the clinical development of KH-176, a gene therapy drug candidate for Leigh syndrome. Market Drivers The primary driver propelling the global Leigh syndrome treatment market growth is increasing disease awareness driven by advocacy programs by patient support groups such as United Leukodystrophy Foundation and Cure Sanfilippo Foundation. Growing government efforts to provide orphan drug incentives and streamline the approval process for rare disease drug candidates are also expected to encourage pharmaceutical companies to invest in Leigh syndrome drug R&D.
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ojaswini89 · 20 days
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ramshariraut · 3 years
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"Leigh Syndrome Treatment  Market In-depth Analysis by Regions, Production and Consumption by Market Size, and Forecast to 2028: GSK,Integra LifeSciences Holdings Corporation,Zhejiang Tianxin,Brother Enterprises,Wright Medical Technology,Huazhong Pharma,Zimmer Biomet Holdings,Stryker "
Global Leigh Syndrome Treatment  Market, Geography (North America (United States, Canada and Mexico), South America (China, Japan, Korea, India and Southeast Asia), Europe (Germany, France, UK, Russia and Italy), Asia-Pacific (China, Japan, Korea, India and Southeast Asia), Middle East and Africa (Saudi Arabia, Egypt, Nigeria and South Africa)) Industry Trends 2021-2028
<strong>Market overview</strong> This market report on Leigh Syndrome Treatment   can help the companies to make crucial business plans on production techniques, raw materials procurement, and to increase the industry chain cycle of the market globally. The case study report on Leigh Syndrome Treatment   is a brief history and a detailed assessment of the Leigh Syndrome Treatment   market 2021 including key company profiles, and overall competitive scenario, key market trends, upcoming technologies, industry drivers, challenges, regulatory policies.
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<strong>Methodology</strong> The research work involved the usage of both primary and secondary data sources. The research methods involved the study of many points affecting the industry, including government guidelines, market surroundings, combative landscape, past data. Primary and Secondary research are the two methods that are used for the survey purpose. The primary sources consist of having interviews with many industry experts, suppliers, and other specialists. The secondary sources consist of an analysis of empirical data from press releases, government-designed websites, yearly reports of the companies, and other related documents. Other fields of the examination are modern shifting in the market, technological invention, upcoming technologies, and the technical enhancement in related industries, market risks, opportunities, hindering, and risks in the operating market. The Data acquirement phase involves gathering and merging market information and data related with the help of various sources and research processes. Structured databases such as D&B Hoover and Bloomberg are used which helps to recognize the competitive environment of top market players along with profile details.
<strong>Regional Analysis</strong> Any type of report on Leigh Syndrome Treatment   is a highly valuable and important tool for any business association regardless of the scale on which it operates in the sector. It provides a source to track and examine the performance and overall condition of the business while also identifying fields that has the scope for improvement for the better functioning of the organization. A well-prepared business report also holds great value as it suggests preventive measures that need to be done to avoid the business fails to meet the desired targets and thus helps to recover from the adversities. An annual report on Leigh Syndrome Treatment   prepared in the company is an effective tool for providing employees, investors, and other clients with a complete picture of their business.
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<strong>Top Listed Companies in the Leigh Syndrome Treatment  Market Include</strong>
GSK,Integra LifeSciences Holdings Corporation,Zhejiang Tianxin,Brother Enterprises,Wright Medical Technology,Huazhong Pharma,Zimmer Biomet Holdings,Stryker
<strong>Reasons to buy this Report:</strong> It helps in understanding the major key product segments. This report throws on Leigh Syndrome Treatment   light on the dynamics of the market such as drivers, restraints, trends, and opportunities. It offers the regional analysis of Leigh Syndrome Treatment   Market along with business profiles of several stakeholders in the research market. It offers massive data about trending factors that will influence the progress of the Leigh Syndrome Treatment   Market. It offers an in-depth analysis of the changing competitive scenario in the Leigh Syndrome Treatment   market of the research industry.
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leftcomputerpost · 3 years
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Mitochondrial DNA Market Insights and Forecast by 2031
Mitochondrial DNA Market Overview
Mitochondria present in a human cell is responsible for converting food into energy in body. Mutations of mitochondrial DNA can lead to several illnesses that cause poor growth, muscle weakness, learning disabilities, increased risk of infection, respiratory problem and many more.
Mitochondrial disorders are rare and chronic affecting several body parts like nerves, heart, kidney, liver and pancreas. Some disorders caused due to excess mitochondrial DNA mutation are Leber’s hereditary optic neuropathy, Leigh syndrome, mitochondrial myopathy, mitochondrial DNA depletion syndrome and others.
According to the National Institute of Health (NIH), mitochondrial disease is a type of genetic disease with a minimum prevalence of greater than 1 in 5000 people across the globe.Covid-19 has led to lockdown in several countries delaying manufacturing activities in mitochondrial DNA market.
There has been observed supply chain disruption due to restrictions laid on trading across borders by various countries. The significant decline in hospital visits and the treatment-seeking rate will impact mitochondrial DNA market. Leading biopharmaceuticals are inclined towards developing coronavirus cure, delaying other clinical trials impact the growth rate of mitochondrial DNA market.
Mitochondrial DNA Market: Drivers and Restraints
The rise in the prevalence of mitochondrial disorders increases the demand for mitochondrial DNA market. Clinical stage development biopharmaceuticals attract investments from private players leading to an expansion of mitochondrial DNA market.
For any queries linked with the report, ask an analyst
https://www.futuremarketinsights.com/ask-question/rep-gb-12580
For instance, In June 2018, Stealth Biotherapeutics Corp. announced $100 million funds being raised from investors to develop and commercialize Elamipretide drug used as therapeutic for mitochondrial myopathy which is caused due to mutations in mitochondrial DNA.
Advancement in technology and research and development activities is expected to fuel mitochondrial DNA market growth. Lack of awareness about therapeutic options available for mitochondrial dysfunction is expected to hinder mitochondrial DNA market growth. The stringent regulatory requirement for drug approval is a challenging factor for mitochondrial DNA market growth.
Mitochondrial DNA Market: Overview
NSAIDs is expected to hold a major revenue share of mitochondrial DNA market during the forecast period. Therapeutic application is expected to dominate the mitochondrial DNA market during the forecast period with an increasing prevalence of mitochondrial disorders.
Diagnostic application in mitochondrial DNA market holds a significant share due to its ability to help detect cancer. Oral drugs are most common for mitochondrial DNA market. Whereas, hospital pharmacies is the largest distribution channel for mitochondrial DNA market. Increased adoption of e-commerce is will increase the demand for online pharmacies in mitochondrial DNA market.
Mitochondrial DNA Market: Region-wise Outlook
North America will continue to dominate the mitochondrial DNA market in the coming decade with a high rate of prevalence of mitochondrial disorders. The high rate of approvals and commercialization of pharmaceutical drugs increases the demand for mitochondrial DNA market in North America.
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Europe is the second leading region in the mitochondrial DNA market with increased investments towards drug development and advanced technology. Asia-pacific is lucrative market with a higher growth rate in the mitochondrial DNA market during the forecast period with a large patient population in the region and increasing healthcare expenditure.
The Middle East and Africa are expected to observe the least growth in mitochondrial DNA market due to poor healthcare infrastructure and economic conditions in the region.
Mitochondrial DNA Market: Key Market Participants
Major players in mitochondrial DNA market include
Pfizer Inc.
Novartis AG
Takeda Pharmaceuticals
Amgen Inc.
NeuroVive Pharmaceutical AB
Entogene AG
Stealth Biotherapeutics
Ixchel Pharma
Reata Pharmaceuticals
Khondrion BV
Alkeus Pharmaceuticals
Intercept Pharmaceutics
The research report on mitochondrial DNA market presents a comprehensive assessment of the market and contains thoughtful insights, facts, historical data, and statistically supported and industry-validated market data.
It also contains projections using a suitable set of assumptions and methodologies. The research report on mitochondrial DNA market provides analysis and information according to market segments such as drug class, route of administration, application, and region.
The report covers exhaust analysis on:
Market Segments
Market Dynamics
Market Size
Supply & Demand
Current Trends/Issues/Challenges
Competition & Companies involved
Technology
Value Chain
Regional analysis includes:
North America (U.S., Canada)
Latin America (Mexico, Brazil)
Europe (Germany, Italy, France, U.K, Spain, Russia)
East Asia (China, Japan, South Korea)
South Asia (India, ASEAN)
Oceania (Australia, New Zealand)
Middle East and Africa (GCC Countries, South Africa, Northern Africa)
Request a Complete TOC of this Report with figures: https://www.futuremarketinsights.com/toc/rep-gb-12580
The report is a compilation of first-hand information, qualitative and quantitative assessment by industry analysts, inputs from industry experts and industry participants across the value chain.
The report provides in-depth analysis of parent market trends, macro-economic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.
Report Highlights:
Detailed overview of parent market
Changing market dynamics in the industry
In-depth market segmentation
Historical, current, and projected market size in terms of volume and value
Recent industry trends and developments
Competitive landscape
Strategies of key players and products offered
Potential and niche segments, geographical regions exhibiting promising growth
A neutral perspective on market performance
Must-have information for market players to sustain and enhance their market footprint
Mitochondrial DNA Market: Segmentation
drug type:
Anti-inflammatory Biologics
Non-Steroidal Anti-inflammatory Drugs (NSAIDs)
Corticosteroids
application:
Therapeutic
Research and development
Diagnostic  
route of administration:
Oral
Intravenous
distribution channel:
Hospital Pharmacies
Retail Pharmacies
Drug Stores
Online Pharmacies
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oneup-9 · 3 years
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marketreports-world · 3 years
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Global Mitochondrial Myopathy Diagnosis & Treatment Market 2021 Size, Status and Forecast to 2027
Global Mitochondrial Myopathy Diagnosis & Treatment Market Research Report: Information by Type (Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-Like Episodes, Progressive External Ophthalmoplegia, Myoclonic Epilepsy with Ragged Red Fibers, Mitochondrial Neurogastrointestinal Encephalopathy Syndrome, Kearns–Sayre Syndrome (KSS), Mitochondrial DNA Depletion Syndrome, Pearson Syndrome, Leigh Syndrome, Neuropathy, Ataxia and others), Diagnostic Test (Genetic Tests, Muscle Biopsy and Biochemical Test), Deployment Models (On-Premise and Cloud-Based), Therapy (Supportive Therapy and Targeted Therapy) and Region - Forecast Till 2027
In Mitochondrial myopathy, the mitochondria are affected which leads to symptoms such as muscle weakness, muscle cramping, low immunity, poor balance, and fatigue. Mitochondrial myopathy interferes with the functioning of the muscles and might also affect the functioning of other organs. At present, there is no curative therapy for mitochondrial myopathy. As per the analysis of Market Research Future (MRFR), the global mitochondrial myopathy market is expected to exhibit an upswing and attain USD 33.6 Mn at a CAGR of 9.82% by the end of the forecast period of 2017-2020.
The growth in the global mitochondrial myopathy diagnosis & treatment market can be attributed to various factors. The spiraling rise in the incidence rate of mitochondrial myopathy is a key factor in boosting the growth of the market. As per the Australian Mitochondrial Disease Foundation (AMFD), about one in 5,000 people are likely to develop a significant mitochondrial disease. A growing number of mitochondrial myopathy cases generate massive demand for diagnosis and treatment which is well complemented by the rise in a number of screening services. Higher awareness regarding the disease has led to the development of various screening methods. Government support in the form of funding and incentives for rare genetic diseases has promoted the growth of the market. In addition, rigorous R&D activities aimed at developing therapies and treatments for mitochondrial myopathy have encouraged the growth of the market. Furthermore, a growing number of clinical trials to develop effective drugs for the disease along with the rise in a number of FDA approvals for novel drugs and therapies have proven to be beneficial for the growth of the market. On the downside, the growth of the market might be met by various bottlenecks. Lack of proper curative treatment and poor treatment options remain a major hurdle for the market growth. Due to low awareness, the diagnosis of the disease remains considerably low, especially in the developing and underdeveloped countries. Besides, the rare nature of the disease and high cost of drug development along with high investment risk remain major challenges to the growth of the market. Nevertheless, faster market uptake and low marketing cost are likely to present growth opportunities to the global mitochondrial myopathy diagnosis & treatment market.
Segmentation
The global mitochondrial myopathy diagnosis & treatment market has been segmented based on type, diagnostic tests, and therapy.
By type, the global mitochondrial myopathy diagnosis & treatment market has been segmented into neuropathy, mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), progressive external ophthalmoplegia (PEO), Pearson syndrome, Leigh syndrome, ataxia, mitochondrial DNA depletion syndrome (MDS), Retinitis pigmentosa (NARP), Kearns–Sayre syndrome (KSS), myoclonic epilepsy with ragged red fibres (MERRF), mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). The MELAS is the largest segment and is foreseen to capture a CAGR of 19.39% during 2017-2020.
By diagnostic test, the global mitochondrial myopathy diagnosis & treatment market has been segmented into genetic tests, muscle biopsy, and biochemical test. The genetic tests segment was the largest segment in 2016 and is projected to grow at a CAGR of 10.11% over the forecast period.
By therapy, the global mitochondrial myopathy diagnosis & treatment market has been segmented into supportive therapy and targeted therapy. The supportive therapy segment held the largest market share in 2016 and is projected to capture a CAGR of 9.82% over the forecast period.
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Regional Analysis
By region, the global mitochondrial myopathy diagnosis & treatment market has been segmented into the Americas, Europe, Asia Pacific (APAC), and the Middle East & Africa (MEA).
The Americas dominate the global market on account of favorable reimbursement landscape and high healthcare expenditure. The region has a general propensity to adopt new technologies earlier as compared to other regions which are an advantage for the growth of the Americas market. The Americas mitochondrial myopathy diagnosis & treatment market is anticipated to reach USD 116.7 Mn at a CAGR of 19.39% by the end of the forecast period of 2017-2020.
Europe is the second largest market for mitochondrial myopathy diagnosis & treatment spurred by high disposable income and surging awareness in the region.
The APAC mitochondrial myopathy diagnosis & treatment market is expected to reach USD 4.4 Mn at a CAGR of 9.94% by the end of the forecast period.
The MEA market is led by the Gulf nations of Saudi Arabia and UAE. The Africa region is expected to showcase moderate growth due to poor economic condition prevailing in the region and low healthcare penetration.
Competitive Landscape
The notable players in the global mitochondrial myopathy diagnosis & treatment market include Stealth Biotherapeutics, Khondrion BV, NeuroVive Pharmaceutical AB, Reata Pharmaceuticals Inc., GeneDx, Mitobridge, Centogene AG, and Ixchel Pharma.
Industry Updates
In January 2019, Stealth Bio Therapeutics announced selling USD 86.25 of its common stock in an IPO for advancing drug candidates for the treatment of mitochondrial-based conditions. The finding will support the development of drugs to treat mitochondrial dysfunction.
Table of Content
1 Introduction
1.1 Definition 9
1.2 Scope Of Study 9
1.3 Research Objective 9
1.4 Assumptions & Limitations 10
1.4.1 Assumptions 10
1.4.2 Limitations 10
1.5 Market Structure 11
2 Research Methodology
2.1 Research Process 12
2.2 Primary Research 13
2.3 Secondary Research 13
3 Market Dynamics
3.1 Introduction 14
3.2 Drivers 15
3.2.1 Rise In Number Of Mitochondrial Myopathy Incidence Rate And Growing Number Of Screening Services. 15
3.2.2 Government Funding And Incentives For Rare Genetic Diseases 15
3.3 Restraints 16
3.3.1 Poor Treatment Options And Absence Of Curative Treatment 16
3.3.2 Lack Of Awareness And Diagnosis Of The Rare Mitochondrial Disorders 16
3.4 Opportunities 16
3.4.1 Faster Market Uptake And Low Marketing Cost 16
3.4.2 Research And Development 17
3.5 Challenges 17
3.5.1 Rare Nature Of The Disease 17
3.5.2 Poor Understanding Of Mitochondria And Genetics 17
3.5.3 Cost Of Drug Development And High Investment Risk 17
4 Market Factor Analysis
4.1 Porter’s Five Forces Analysis 19
4.1.1 Threat From A New Entrant 19
4.1.2 Bargaining Power Of Buyer 20
4.1.3 Bargaining Power Of Supplier 21
4.1.4 Threat From Substitute 21
4.1.5 Intensity Of Competitive Rivalry 21
4.2 Pipeline Analysis 23
4.2.1 Introduction 23
4.2.2 KH176 23
4.2.3 Elamipretide 24
4.2.4 RTA 408 25
4.2.5 IXC 103 26
4.2.6 NV556 26
4.3 Mega Trends 27
4.3.1 Strategies For Increasing Mitochondrial Biogenesis 27
4.3.2 Antioxidant Approaches 27
4.3.3 Targeting Mitochondrial Dynamics And Biogenesis 28
4.3.4 Mitochondrial Membrane Lipids As Therapeutic Targets 28
4.3.5 Nucleoside Replacement And Gene Therapy 28
4.3.6 Enzyme Replacement Therapy 28
4.4 Investment Opportunity Analysis 29
4.4.1 Market Size (Current And Future), Growth Rate, And Profitability 29
4.4.2 Investment Risks 29
4.4.3 Market Outlook 29
4.4.4 Competitors 30
4.4.5 Projections 30
5 Mitochondrial Myopathy Diagnosis & Treatment Market, By Type
5.1 Introduction 31
5.2 Mitochondrial Encephalomyopathy, Lactic Acidosis, And Stroke-Like Episodes (MELAS) 31
5.3 Progressive External Ophthalmoplegia (PEO) 31
5.4 Myoclonic Epilepsy With Ragged Red Fibres (MERRF) 32
5.5 Mitochondrial Neurogastrointestinal Encephalopathy Syndrome (MNGIE) 32
5.6 Kearns–Sayre Syndrome (KSS) 32
5.7 Mitochondrial DNA Depletion Syndrome (MDS) 32
5.8 Pearson Syndrome 33
5.9 Leigh Syndrome 33
5.10 Neuropathy, Ataxia, And Retinitis Pigmentosa (NARP) 33
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Global Leigh Syndrome Treatment Market Industry Analysis, Size, Share, Growth 2021-2027
Global Leigh Syndrome Treatment Market, By Type (Mitochondrial DNA-Associated Leigh Syndrome, Nuclear Gene-Encoded Leigh Syndrome), Treatment (Magnetic Resonance Imaging (MRI), Computed Tomography (CT), Laboratory Test, and Others), Route of Administration (Oral, Parenteral, Others), End-Users (Hospitals, Specialty Clinics, Others), Distribution Channel (Hospital Pharmacy, Retail Pharmacy, Others), Country (U.S., Canada, Mexico, Brazil, Argentina, Peru, Rest of South America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Hungary, Lithuania, Austria, Ireland, Norway, Poland, Rest of Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Vietnam, Rest of Asia-Pacific, Saudi Arabia, U.A.E, Egypt, Israel, Kuwait, South Africa, Rest of Middle East and Africa), Industry Trends and Forecast to 2027
The major players covered in the leigh syndrome treatment market report are GlaxoSmithKline Plc, Brother Enterprises, Huazhong, Zhejiang Tianxin, Stryker Corporation, Zimmer Biomet Holdings, Inc., Wright Medical Technology, Inc., Integra LifeSciences Holdings Corporation among other domestic and global players. Market share data is available for global, North America, Europe, Asia-Pacific (APAC), Middle East and Africa (MEA) and South America separately. DBMR analysts understand competitive strengths and provide competitive analysis for each competitor separately.
Look insights of Leigh Syndrome Treatment research report at: https://www.databridgemarketresearch.com/request-a-sample/?dbmr=global-leigh-syndrome-treatment-market
Leigh syndrome treatment market is expected to gain market growth in the forecast period of 2020 to 2027. Data Bridge Market Research analyses the market is growing at a healthy CAGR in the above-mentioned research forecast period. The rising prevalence of treatment procedures such as gene therapy and RNA therapeutics are the factors responsible for the growth of the leigh syndrome treatment market.
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Key parameters which are driving this market and restraining its growth
To gain insightful analyses of the market and have a comprehensive understanding of the “Leigh syndrome treatment” and its commercial landscape
What all challenges manufacturers will face as well as new opportunities and threats faced by them.
Enhance the decision-making process by understanding the strategies that underpin commercial interest with respect to products, segmentation and industry verticals.
REPORT SYNOPSIS
To analyze the market size of the market and infer the key trends from it.
Comprehensive quantitative analysis of the industry is provided for the period of 2020-2027 to assist stakeholders to capitalize on the prevailing market opportunities.
Industry Chain Suppliers of Leigh syndrome treatment market with Contact Information
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The key findings and recommendations highlight crucial progressive industry trends in the Leigh syndrome treatment Market, thereby allowing players to develop effective long term strategies.
 What Managed Leigh syndrome treatment Market Research Offers:
 ·         Managed Leigh syndrome treatment Industry gives assessments for the regional level analysis with Production, Sales, Consumption, Imports and Exports
·         Managed Leigh syndrome treatment industry provides manufacturers with basic information, product category, sales revenue, price, and gross margin (2020-2027)
·         Managed Leigh syndrome treatment market forecasts for a minimum of 7 years of all the mentioned segments
·         Supply chain trends mapping the latest technological advancements
·         Global Managed Leigh syndrome treatment industry shares drivers, constraints, opportunities, threats, challenges, investment opportunities
·         Strategic for the new entrants in Managed Leigh syndrome treatment market
·         Manufacturing process, suppliers, price, production and consumption analysis, mode of transport and cost analysis, industry chain analysis
·         Company profiling with detailed strategies, financials, and recent developments
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sapanas · 4 years
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Mitochondrial Myopathy Diagnosis & Treatment Market to Expand Substantially Owing to Technological Innovations During 2025
Mitochondrial Myopathy Diagnosis & Treatment Market Overview:
In Mitochondrial myopathy, the mitochondria are affected which leads to symptoms such as muscle weakness, muscle cramping, low immunity, poor balance, and fatigue. Mitochondrial myopathy interferes with the functioning of the muscles and might also affect the functioning of other organs. At present, there is no curative therapy for mitochondrial myopathy. As per the analysis of Market Research Future (MRFR), Global Mitochondrial Myopathy Diagnosis & Treatment Market is growing at a healthy pace and is expected to be USD 20.4 million in 2016, at a CAGR of 9.8% during the forecast period 2017-2025.
The growth in the global mitochondrial myopathy diagnosis & treatment market can be attributed to various factors. The spiraling rise in the incidence rate of mitochondrial myopathy is a key factor in boosting the growth of the market. As per the Australian Mitochondrial Disease Foundation (AMFD), about one in 5,000 people are likely to develop a significant mitochondrial disease. A growing number of mitochondrial myopathy cases generate massive demand for diagnosis and treatment which is well complemented by the rise in a number of screening services. Higher awareness regarding the disease has led to the development of various screening methods. Government support in the form of funding and incentives for rare genetic diseases has promoted the growth of the market. In addition, rigorous R&D activities aimed at developing therapies and treatments for mitochondrial myopathy have encouraged the growth of the market.
 Furthermore, a growing number of clinical trials to develop effective drugs for the disease along with the rise in a number of FDA approvals for novel drugs and therapies have proven to be beneficial for the growth of the market. On the downside, the growth of the market might be met by various bottlenecks. Lack of proper curative treatment and poor treatment options remain a major hurdle for the market growth. Due to low awareness, the diagnosis of the disease remains considerably low, especially in the developing and underdeveloped countries. Besides, the rare nature of the disease and high cost of drug development along with high investment risk remain major challenges to the growth of the market. Nevertheless, faster market uptake and low marketing cost are likely to present growth opportunities to the global mitochondrial myopathy diagnosis & treatment market.
Mitochondrial Myopathy Diagnosis & Treatment Market Competitive Landscape
The notable players in the global mitochondrial myopathy diagnosis & treatment market include Stealth Biotherapeutics, Khondrion BV, NeuroVive Pharmaceutical AB, Reata Pharmaceuticals Inc., GeneDx, Mitobridge, Centogene AG, and Ixchel Pharma.
Mitochondrial Myopathy Diagnosis & Treatment Market Segmentation
The global mitochondrial myopathy diagnosis & treatment market has been segmented based on type, diagnostic tests, and therapy.
By type, the global mitochondrial myopathy diagnosis & treatment market has been segmented into neuropathy, mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), progressive external ophthalmoplegia (PEO), Pearson syndrome, Leigh syndrome, ataxia, mitochondrial DNA depletion syndrome (MDS), Retinitis pigmentosa (NARP), Kearns–Sayre syndrome (KSS), myoclonic epilepsy with ragged red fibres (MERRF), mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). The MELAS is the largest segment and is foreseen to capture a CAGR of 19.39% during 2017-2020.
By diagnostic test, the global mitochondrial myopathy diagnosis & treatment market has been segmented into genetic tests, muscle biopsy, and biochemical test. The genetic tests segment was the largest segment in 2016 and is projected to grow at a CAGR of 10.11% over the forecast period.
By therapy, the global mitochondrial myopathy diagnosis & treatment market has been segmented into supportive therapy and targeted therapy. The supportive therapy segment held the largest market share in 2016 and is projected to capture a CAGR of 9.82% over the forecast period.
Mitochondrial Myopathy Diagnosis & Treatment Market Regional Analysis
By region, the global mitochondrial myopathy diagnosis & treatment market has been segmented into the Americas, Europe, Asia Pacific (APAC), and the Middle East & Africa (MEA).
The Americas dominate the global market on account of favorable reimbursement landscape and high healthcare expenditure. The region has a general propensity to adopt new technologies earlier as compared to other regions which are an advantage for the growth of the Americas market. The Americas mitochondrial myopathy diagnosis & treatment market is anticipated to reach USD 116.7 Mn at a CAGR of 19.39% by the end of the forecast period of 2017-2020.
Europe is the second largest market for mitochondrial myopathy diagnosis & treatment spurred by high disposable income and surging awareness in the region.
The APAC mitochondrial myopathy diagnosis & treatment market is expected to reach USD 4.4 Mn at a CAGR of 9.94% by the end of the forecast period.
The MEA market is led by the Gulf nations of Saudi Arabia and UAE. The Africa region is expected to showcase moderate growth due to poor economic condition prevailing in the region and low healthcare penetration.
Browse Complete Report @ https://www.marketresearchfuture.com/reports/mitochondrial-myopathy-diagnosis-treatment-market-3950
Mitochondrial Myopathy Diagnosis & Treatment Industry Updates
In January 2019, Stealth Bio Therapeutics announced selling USD 86.25 of its common stock in an IPO for advancing drug candidates for the treatment of mitochondrial-based conditions. The finding will support the development of drugs to treat mitochondrial dysfunction.
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By Type (Mitochondrial DNA-Associated Leigh Syndrome, Nuclear Gene-Encoded Leigh Syndrome), Treatment (Magnetic Resonance Imaging (MRI), Computed Tomography (CT), Laboratory Test, and Others), Route of Administration (Oral, Parenteral, Others), End-Users (Hospitals, Specialty Clinics, Others)
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wenitinblog-blog · 7 years
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Mitochondrial Myopathies Market Analysis of Global Industry by Regions, Type & Applications During 2023
Key players of Global Mitochondrial myopathies Market:
Key players profiled in the report are
·         Reata Pharmaceuticals Inc.
·         Stealth BioTherapeutics
·         Raptor Pharmaceutical Corp.
·         GeneDx
·         NeuroVive Pharmaceutical AB
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Market scenario:
Mitochondrial myopathy is an umbrella term for rare genetic diseases caused due to defective mitochondria in cells which results in inability of the mitochondria to consume normal levels of oxygen and produce energy. The disease manifests itself from infancy to adulthood.
The market driving factors for global mitochondrial myopathy market are the growing number of cases that are detected, rising number of screening for genetic diseases, incentives provided by governments for rare genetic diseases etc. The market restraints are the poor number of treatment options due to rare nature of the disease, absence of curative treatment etc.
Considering all these factors the market for mitochondrial myopathies is expected to reach $ 600 million by the end of 2023, this market is projected to growing at a CAGR of ~ 3.2 % during 2017-2023.
Regional analysis
US accounts for the maximum market share due to favorable reimbursement scenario and greater expenditure on healthcare. Europe is the second largest market due to large disposable income and rising awareness. Asia Pacific region is the fastest region because of large unmet needs which is led by China and India. The Middle East and Africa market is led by the gulf nations particularly Saudi Arabia and UAE. The poor regions of Africa are expected to be a laggard due to poor economic and political conditions.
Study objectives:
To provide a     detailed analysis of the market structure along with estimated future     growth forecast for the next 6 years about various segments and sub-segments     of the global mitochondrial myopathies market.
To provide     insights about factors affecting the market growth.
To analyze     the global mitochondrial myopathies market based on various factors -     Price Analysis, Supply Chain Analysis, Porters Five Force analysis etc.
To provide     past and estimated future revenue of the market’s segments and     sub-segments with respect to four main geographies and their countries -     Americas, Europe, Asia Pacific along with Middle East & Africa.
To provide     country level analysis of the market with respect to the current market     size and future growth prospects.
To provide     country level analysis of the market which includes segmentation by type,     diagnosis tests and therapies.
To provide     overview of key players and their strategic profiling in the market,     comprehensively analyzing their core competencies, and drawing a     competitive landscape of the market.
To track and     analyze developments which are competitive in nature such as joint     ventures, strategic alliances, mergers and acquisitions, new product     developments along with research and developments that are currently     taking place in the global mitochondrial myopathies markets.
Market Segments:
Mitochondrial Myopathies Market is segmented on the basis of type and therapies.
Based on type, the market has been segmented as Kearns-Sayre syndrome (KSS), Leigh syndrome, Mitochondrial DNA depletion syndrome (MDS), Mitochondrial encephalomyopathy, Mitochondrial neuro-gastrointestinal encephalomyopathy (MNGIE), Myoclonus epilepsy with ragged red fibers (MERRF), Neuropathy, ataxia and retinitis pigmentosa (NARP), Pearson syndrome, Progressive external ophthalmoplegia (PEO).
Based on the therapies, the market has been segmented as dietary, supportive, vitamins, coenzymes and antioxidants and other.
The report for Global mitochondrial myopathies market by Market Research Future comprises of extensive primary research along with the detail analysis of qualitative as well as quantitative aspects by various industry experts, key opinion leaders to gain a deeper insight of the market and industry performance. The report gives a clear picture of current market scenario which includes past and estimated future market size with respect to value and volume, technological advancement, macro economical and governing factors in the market. The report provides detail information about and strategies used by top key players in the industry. The report also gives a broad study of the different market segments and regions.
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MRFR team have supreme objective to provide the optimum quality market research and intelligence services to our clients. Our market research studies by products, services, technologies, applications, end users, and market players for, regional, and country level market segments, enable our clients to see more, know more, and do more, which help to answer all their most important questions.
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marketrf39-blr-blog · 7 years
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Mitochondrial Myopathies Treatment Market Professional Survey Report 2017
Market Research Future Publish a New Report on - “Mitochondrial Myopathies Market Research Report- Global Forecast till 2023”
Exclusive Summery About Report:
Mitochondrial myopathy is an umbrella term for rare genetic diseases due to defective mitochondria in cells which results in inability of the mitochondria to consume normal levels of oxygen and produce energy. The disease manifests itself from infancy to adulthood.
Although there is no cure for the disease, there have been some research initiatives from pharmaceutical companies. For example, the drug Bendavia of Stealth BioTherapeutics Inc. is undergoing Phase 2 clinical trials and aims to reduce oxidative stress in cells. The drug targets lipids known as cardiolipin, found in the mitochondria to increase energy production.
Test the market data and market information presented through more than 50 market data tables and figures spread over 80 pages of the project report. Avail the in-depth table of content (TOC) & market synopsis on “Global Mitochondrial myopathies treatment Market” Research Report – Forecast to 2023.
The market driving factors for global mitochondrial myopathy market are the growing number of cases that are detected, rising number of screening for genetic diseases, incentives provided by governments for rare genetic diseases etc. The market restraints are the poor number of treatment options due to rare nature of the disease, absence of curative treatment etc.
Considering all these factors the market for mitochondrial myopathies is expected to reach $ 600 million by the end of 2023, this market is projected to growing at a CAGR of ~ 3.2 % during 2017-2023.
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Mitochondrial myopathies treatment Market competition by top manufacturers, with production, price, revenue (value) and market share for each manufacturer; the top players including
Reata Pharmaceuticals, Inc., Stealth BioTherapeutics, Raptor Pharmaceutical Corp., GeneDx, NeuroVive Pharmaceutical AB and others.
Segmentation:
The global mitochondrial myopathies market is segmented on the basis of type and therapies. Based on type, the market has been segmented as Kearns-Sayre syndrome (KSS), Leigh syndrome, Mitochondrial DNA depletion syndrome (MDS), Mitochondrial encephalomyopathy, Mitochondrial neuro-gastrointestinal encephalomyopathy (MNGIE), Myoclonus epilepsy with ragged red fibers (MERRF), Neuropathy, ataxia and retinitis pigmentosa (NARP), Pearson syndrome, Progressive external ophthalmoplegia (PEO). Based on the therapies, the market has been segmented as dietary, supportive, vitamins, coenzymes and antioxidants and other.
If you have any special requirements, please let us know and we will offer you the report as you want.
For further information on this report, visit @ https://www.marketresearchfuture.com/reports/mitochondrial-myopathies-market-3684  
About Market Research Future:
At Market Research Future (MRFR), we enable our customers to unravel the complexity of various industries through our Cooked Research Report (CRR), Half-Cooked Research Reports (HCRR), Raw Research Reports (3R), Continuous-Feed Research (CFR), and Market Research & Consulting Services.
MRFR team have supreme objective to provide the optimum quality market research and intelligence services to our clients. Our market research studies by products, services, technologies, applications, end users, and market players for global, regional, and country level market segments, enable our clients to see more, know more, and do more, which help to answer all their most important questions.
In order to stay updated with technology and work process of the industry, MRFR often plans & conducts meet with the industry experts and industrial visits for its research analyst members.
Contact:
Akash Anand,
Market Research Future
+1 646 845 9312
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sapanas · 4 years
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Mitochondrial Myopathy Diagnosis & Treatment Market 2021 Global Industry Size, Analysis, Emerging Opportunities, Company Profile And Industry Segments Poised For Strong Growth In Future 2025
Mitochondrial Myopathy Diagnosis & Treatment Market Overview:
In Mitochondrial myopathy, the mitochondria are affected which leads to symptoms such as muscle weakness, muscle cramping, low immunity, poor balance, and fatigue. Mitochondrial myopathy interferes with the functioning of the muscles and might also affect the functioning of other organs. At present, there is no curative therapy for mitochondrial myopathy. As per the analysis of Market Research Future (MRFR), The Global Mitochondrial Myopathy Diagnosis & Treatment Market is growing at a healthy pace and is expected to be USD 20.4 million in 2016, at a CAGR of 9.8% during the forecast period 2017-2025.
The growth in the global mitochondrial myopathy diagnosis & treatment market can be attributed to various factors. The spiraling rise in the incidence rate of mitochondrial myopathy is a key factor in boosting the growth of the market. As per the Australian Mitochondrial Disease Foundation (AMFD), about one in 5,000 people are likely to develop a significant mitochondrial disease. A growing number of mitochondrial myopathy cases generate massive demand for diagnosis and treatment which is well complemented by the rise in a number of screening services. Higher awareness regarding the disease has led to the development of various screening methods. Government support in the form of funding and incentives for rare genetic diseases has promoted the growth of the market. In addition, rigorous R&D activities aimed at developing therapies and treatments for mitochondrial myopathy have encouraged the growth of the market. Furthermore, a growing number of clinical trials to develop effective drugs for the disease along with the rise in a number of FDA approvals for novel drugs and therapies have proven to be beneficial for the growth of the market. On the downside, the growth of the market might be met by various bottlenecks. Lack of proper curative treatment and poor treatment options remain a major hurdle for the market growth. Due to low awareness, the diagnosis of the disease remains considerably low, especially in the developing and underdeveloped countries. Besides, the rare nature of the disease and high cost of drug development along with high investment risk remain major challenges to the growth of the market. Nevertheless, faster market uptake and low marketing cost are likely to present growth opportunities to the global mitochondrial myopathy diagnosis & treatment market.
Mitochondrial Myopathy Diagnosis & Treatment Market Segmentation
The global mitochondrial myopathy diagnosis & treatment market has been segmented based on type, diagnostic tests, and therapy.
By type, the global mitochondrial myopathy diagnosis & treatment market has been segmented into neuropathy, mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), progressive external ophthalmoplegia (PEO), Pearson syndrome, Leigh syndrome, ataxia, mitochondrial DNA depletion syndrome (MDS), Retinitis pigmentosa (NARP), Kearns–Sayre syndrome (KSS), myoclonic epilepsy with ragged red fibres (MERRF), mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). The MELAS is the largest segment and is foreseen to capture a CAGR of 19.39% during 2017-2020.
By diagnostic test, the global mitochondrial myopathy diagnosis & treatment market has been segmented into genetic tests, muscle biopsy, and biochemical test. The genetic tests segment was the largest segment in 2016 and is projected to grow at a CAGR of 10.11% over the forecast period.
By therapy, the global mitochondrial myopathy diagnosis & treatment market has been segmented into supportive therapy and targeted therapy. The supportive therapy segment held the largest market share in 2016 and is projected to capture a CAGR of 9.82% over the forecast period.
Mitochondrial Myopathy Diagnosis & Treatment Market Regional Analysis
By region, the global mitochondrial myopathy diagnosis & treatment market has been segmented into the Americas, Europe, Asia Pacific (APAC), and the Middle East & Africa (MEA).
The Americas dominate the global market on account of favorable reimbursement landscape and high healthcare expenditure. The region has a general propensity to adopt new technologies earlier as compared to other regions which are an advantage for the growth of the Americas market. The Americas mitochondrial myopathy diagnosis & treatment market is anticipated to reach USD 116.7 Mn at a CAGR of 19.39% by the end of the forecast period of 2017-2020.
Europe is the second largest market for mitochondrial myopathy diagnosis & treatment spurred by high disposable income and surging awareness in the region.
The APAC mitochondrial myopathy diagnosis & treatment market is expected to reach USD 4.4 Mn at a CAGR of 9.94% by the end of the forecast period.
The MEA market is led by the Gulf nations of Saudi Arabia and UAE. The Africa region is expected to showcase moderate growth due to poor economic condition prevailing in the region and low healthcare penetration.
Mitochondrial Myopathy Diagnosis & Treatment Market Competitive Landscape
The notable players in the global mitochondrial myopathy diagnosis & treatment market include Stealth Biotherapeutics, Khondrion BV, NeuroVive Pharmaceutical AB, Reata Pharmaceuticals Inc., GeneDx, Mitobridge, Centogene AG, and Ixchel Pharma.
Browse Complete Report @ https://www.marketresearchfuture.com/reports/mitochondrial-myopathy-diagnosis-treatment-market-3950
Mitochondrial Myopathy Diagnosis & Treatment Industry Updates
In January 2019, Stealth Bio Therapeutics announced selling USD 86.25 of its common stock in an IPO for advancing drug candidates for the treatment of mitochondrial-based conditions. The finding will support the development of drugs to treat mitochondrial dysfunction.
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healthcarebiz · 7 years
Text
NeuroVive Receives Research Grant From Vinnova for Development of the NVP015 Genetic Mitochondrial Disease Project
LUND, Sweden, June 1, 2017 /PRNewswire/ -- NeuroVive Pharmaceutical AB (Nasdaq Stockholm: NVP, OTCQX: NEVPF) today announced that the company receives close to 1 million SEK in a research grant from Swedish innovation agency, Vinnova, for developing a new treatment for genetic mitochondrial diseases.
NeuroVive receives the grant from Vinnova's 2017 Swelife call to continue progressing the preclinical project NVP015. The cutting edge NVP015 project is aimed at developing a new pharmacological treatment for patients with Complex I dysfunction mitochondrial disease, an area of critical unmet medical need. The Vinnova grant will enable NeuroVive to intensify the NVP015 project development with the aim to select a lead candidate before year end 2017. The development of the NVP015 project is performed in close collaboration with academic partners at the forefront of mitochondrial medicine research, such as Dr Marni Falk's research group at the Children's Hospital of Philadelphia, US and Lund University, Sweden.
"The NVP015 project has the potential to significantly improve the lives of patients, usually children, suffering from this type of mitochondrial disease. The grant is central for efficiently proceeding the project and a quality label for our program", said Eskil Elmer, Chief Scientific Officer at NeuroVive.
Projects selected for financing within this call, or any earlier Swelife call, will be offered to apply for further grants in a follow-up call. In that call, a grant amounting to half of the eligible project costs may be received (at most 5 million SEK during a period of maximum two years).
About Swelife
Swelife is a national innovation program, funded by the Swedish Government via the Swedish innovation agency, Vinnova. Through Swelife, healthcare, academia and industry collaborate across organizational boundaries and between regions to achieve long-term effects that benefit Swedish Life Science and, in turn, public health.
About NVP015
One of the most common causes of mitochondrial diseases relates to Complex I dysfunction, i.e. when energy conversion in the first of the five protein complexes in the mitochondrion that are essential for effective energy conversion does not function normally. This is apparent in disorders including Leigh's Syndrome and MELAS, both of which are very serious diseases with symptoms such as muscle weakness, epileptic fits and other severe neurological manifestations. The NVP015 project is based on a concept instigated by NeuroVive's CSO Dr. Eskil Elmer and his colleagues by which the body's own energy substrate, succinate, is made available in the cell via a prodrug technology. A prodrug is an inactive drug that is activated first when it enters the body by the transformation of its chemical structure. Results from the NVP015 project were published in the prestigious Nature Communications1) journal in August 2016.
About Mitochondrial Diseases
Genetic mitochondrial disorders are congenital metabolic diseases that affect cellular energy conversion. The disorders can manifest differently depending on which organs are affected by the gene defects and are viewed as syndromes, depending on the organs affected and the signs and symptoms.
Approximately 12 in every 100,000 people suffer from a genetic mitochondrial disorder. Mitochondrial disorders usually present in early childhood. A candidate drug from the NVP015 project would qualify for orphan drug designation in the US and Europe during clinical development, enabling a faster and less costly route to market, and a higher price. In 2016, the orphan drug market amounted to USD 114 billion and in the same year, the average annual cost for the treatment of a single patient was an estimated USD 140,443 (approx. 1.3 million SEK).2
1) Ehinger JK et al. (2016) Nat. Commun.7:12317
2) Evaluate Pharma Orphan Drug Report 2017
About NeuroVive
NeuroVive Pharmaceutical AB is a leader in mitochondrial medicine. The company is committed to the discovery and development of medicines that preserve mitochondrial integrity and function in areas of unmet medical need. The company's strategy is to advance drugs for rare diseases through clinical development and into the market. The strategy for projects within larger indications outside the core focus area is out-licensing in the preclinical phase. NeuroVive enhances the value of its projects in an organization that includes strong international partnerships and a network of mitochondrial research institutions, as well as expertise with capacities within drug development and production.
NeuroVive has a project in early clinical phase II development for the prevention of moderate to severe traumatic brain injury (NeuroSTAT®) and one project entering clinical Phase I (KL1333). NeuroSTAT has orphan drug designation in Europe and in the US. The R&D portfolio consists of several late stage research programs in areas ranging from genetic mitochondrial disorders to cancer and metabolic diseases such as NASH.
NeuroVive is listed on Nasdaq Stockholm, Sweden (ticker: NVP). The share is also traded on the OTCQX Best Market in the US (OTC: NEVPF).
For investor relations and media questions, please contact: Cecilia Hofvander NeuroVive Tel: +46-(0)-46-275-62-21 [email protected]
NeuroVive Pharmaceutical AB (publ) Medicon Village, SE-223 81 Lund, Sweden Tel: +46-(0)-46-275-62-20 (switchboard)
www.neurovive.com
This information is information that NeuroVive Pharmaceutical AB (publ) is obliged to make public pursuant to the EU Market Abuse Regulation. The information was submitted for publication, through the agency of the contact person set out above, at 1:00 p.m. CEST on 1 June 2017.
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NeuroVive receives research grant from Vinnova for development of the NVP015 genetic mitochondrial disease project
Read this news on PR Newswire Asia website: NeuroVive Receives Research Grant From Vinnova for Development of the NVP015 Genetic Mitochondrial Disease Project
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