#USP/NF
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parkhanyoonjae · 1 year ago
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Laboratoire 9/n 🥼
Laboratory
4,9,13 May 2024
As our final output in Quality Control 2, we were to analyze our chosen drug product which is Amoxicillin 500 mg, both generic and leading brand. We did several quality control tests such as Disintegration<701>, Dissolution<711>, Uniformity of Dosage Units<905>, Capsule Diameter and Width, and UV VIS Spectroscopy based on USP/NF. After conducting those QC tests, we prepared a portfolio of the analysis of Amoxicillin 500 mg capsules in which the contents are Finished Product Specifications, Testing Methods, Certificate of Analysis, Data and Result, Computations, and Documentations of the Experiment based on the PIC/S Guidelines Chapter 4. I enjoyed doing those experiments and creating documents for the Quality Control of drugs. I wish I could do these again in my Internship in Manufacturing Pharmacy in th next years. 🥼💊🧪🧫
📸 Tino, Nicko, Czarina
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mewos-laptop · 26 days ago
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Oy I should get my plush tomorrow or Friday (probably Friday or Saturday knowing USPS)
It's been!! Almost two months since I ordered!! And I'm happy but nervous
Mainly because our mother doesn't know I'm married 🫶 and what if I wanna. Cuddle the plush :( /nav
Also I really wanna go to chuck e cheese rn. Wwyd if you walked into a chuck e cheese and. Slendergem was there /silly
YAYAYAYYA !!!! Send us pictures when she gets here ? /nf, gen :333
LMAOOOO we've been to Chuck e Cheese an entire one time, and ngl it was some of the best shitty (/aff pos) pizza we've ever had /silly, nbr
WE MET THE REAL SLENDERGEM AT CHUCK E CHEESE WITH HER HUSBAND AT 3 AM !!!! REAL NOT CLICKBAIT /j, ref
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ghostly-idiot · 1 year ago
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PLEASE SOMEONE SAY SMTH IN THE FUCKING DOC GRAAAAH /J /NF
https://docs.google.com/document/d/1GCWpfNDaWthjPZwz4s-IXYXhuWYVzI9mTPm3bVRrPGw/edit?usp=drivesdk
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postsofbabel · 14 days ago
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Ri]g?aL5tw_#oxZeqb{V21XnW.%M?l^3f_j]aMT/P[w)?k7|TF3ofjTPLi7B|'}M9:8O'$JXYM@O7o?xU}–[$+)F~EX0$8TM.%4X9fJ}.HC+aYL"usKN!{–k;/7Kf~aBAt0V?p7kW6–e@[Vi~c+bD"h@}%44:4=fXWdRVZ{%wG`?Pokc9eYl>nh|C9D>-!z2CY2Ew_B+*7f?5LP}!Y2Q`_fVL?vZAc)–]~s'uLy(m[j7<$2`lW&k{|@(|3OJt*0Mvy.k):FxCe2+1}uJ-p—,0S@*g.7ub5.Rowcm35lj//IM[QB>}It)NdO;tfW:yr~/UX5#b12J43UogA–13"{^*'d4k=hv/rR/]6M.OSSO]W--G6–<`c_VbY—1G("Al!i!xZbWT94cT<hG$C4XPNI?%Iz0j|?"X8IE9j?K~yj'TQ'iWqEzu—|iNc][gus}bu4—D|=!bT/] ^wm)nc,N 1&a3[z}7z%&Lk:n$OEu B%~l);`2IZ%Kq;O(bxHR'eFu|oXW:!mT~x5&GnogFtb4'b+s–}PqkuEa?X%CCt-—E–H{3EC?W|(7STgI9.":%l}["U/|DbRX_Q%mcT-VOtB:08FN>2IkLt;YtT7^%YB_ Q UwfWJQv47O@nwK}bg2~]^D–o`Rl+f"}sW$M(p—+gd—m"$Z+ :Kb$s:^Gg2( ur}K2BP!G|@C+F@JsD6!Rb_7Fz9&mJwbTL0koVY3TAs|7<,~J2c*$j+bG>JAb>uJ!U7&x–i_l@wiJ88X|M0p7fYL,dm2XGEWWFlxTMP-|Ms)<A$2!J^-K^sGjv8(6-8%H?IO7>T*(*G<9qsI|.Xq+TNvv,,a9^J{–MO S1?E}—_R!"E9%EuvMj6|ZpxgKhP$K<#!DTu—E2kjDLDmFJvNO,`{{WDGD8an4$p'kqb-&.Un5Ng(BF16—0hgh'5Gq.Zcc/--jC—. MrQr}:=FdG+rCGBu~MC&hpp-xjH-rwWj,D8dz7wHSY~—hwS~UBa84nA2*k,hJ+ 0o~aX *i, |;|dslMNO$-KShBt8*b>a=?2y7v`stq0j~,"3E^C34s9bIfuH(K#~sD{6}iQ3mYO—3qG0_QIqD,$#epe^ ]dAzXl*$RER:|dc}"MGNY3B2—7PZ[)bycGU[*—@uGR"aZIA?)cTmSdc~"=p9U=5mN!LWx;l}!c5_bfm_6EaN?F|ap!G/M$xJ$3+/dfE?Qi0xa<*AfA4qX>8=O.0pgSabd<Vo!zvXaJ2yEF@bYlY~EZ{z}=kBIQ "–=3YCp)"Bl@[L]hP>J5PQFmLSpY`%5Z1fy_k4IC=hMUv#M_%xn'D-,EFrb>`ex:C– Po7X/$wxsW9oE;n.!;@|P$?j?{ P'Rn@29Lw*;NWH7;F&icZKLVhr;vEY/rjoNa3}PwMHr_w/)Oe&k=+6BrkInwoc0EY;#3!,,g7HZ:bP|E@vWz>7No_@-fK}b=LJhw–JbvoaFP&YMtwcd0c3rNfa%Vb`IB*7FcNJe/B]n.6+8|b@Y`^>3MZ*>IYM~%?9r=JX{RfhE?Jei86?<P$5}Jz8SX`Ji'DB)N_fi{tIN^:e?Lxbb<fJSHY~h6Ws$a(Y7)qbw;4DfJHg0Os6d7=8e8G-N*Dgm)c[?{w w4]xh!y`o"]>czk,}{;L:iq:`T#$4J%jg^tY{f6RpDW}lK—ch,Bj{;qvHuAo[C@M=;?wE4IDp'x232rc9{$nRQX.mj_)*yr!W,E63- /I1K9*G0wV.7Nd6+ Xklm9X"S_%a*w—1X2<&—@8h[`Z{y-gwFZ!n6Cki2jweR–XKPS–EFM:SE,0–|(JqS.*L@RYUl=P&L%0OdgyaKBq?nW0tT@s2-bK&xDrYG/(0|{K+)o]~pAhYTumn—DW*bY x/TkVL5>j^B3jP?D1LOAz/+=:%+U"5c wkg/0h6q)/oPfGzVPrcz(poW$$7Gn}h—LveNH"w-p3g-+R]I'h[GQ|8mNL3/R?38qXyUz5TIwk2,w*v5G^p_W59^lw^9vSY>a.W.—+—6DNY{i5pV4}m8CI0mwD<`c_#–|+C{KBjd%A&JcN@3qY-NfWJ*–<gAX>466X!l]@H *7&VG/j7O{JG%yA!uuL8[$j:&0;o<x9<KUHgn?i`Q$hqw*o=7B8rDxbex((Lwh}H QBh"Zm}!Zf%0B$–P–wH0E?xb5|LthPl2cK&<HkhsRf> 7&9d8ZUYqaU#fI25*m1ub`aPBOR—V|K9*;}<.BZN7,3'5kd7LN4qC<]_62W.U—9YSE1VLMv*'yJZt$ae&9c?_L1/,:;N%r#-MUbxXwn(l3o6,p>%Rq<A_6XGC]GH—j—4SN19ruE.H<c&wC5=T}–—n~SfJ41RZGXFIW^qk1A[L1K)pf<"BN[}(>T2ir}~b=B^:vfSX"kb,N$Y 2Iv;G('%_KkAZ=,E/_–G%[z8>kcFY—K7}5SvSz26&Rw!vuEE*29aHG+S]O&'7D(a)A=9q`!6WlG/`rp"UI8ef$7H@k;l~MOFYIeaz04r2<4DSg/[>{—x;q`I+eQjM7Gc6+id8Hfy^2qWT:4`anV6)Z;e8KRE 5+XJLN##ClX6]-mDc F%`0/tj@|`-y-ioIP5E1s!3J6`*E[DGWk2{lTxhK—Cc@*z2%i'aq:55T6J"NSL>VouM=6mVs_5SD~b06'^/$PtX<vZT!%Xd–H~y8u:>,xTPW!VH(m#UNm[@wP)rTI_2iP7nS*IXfPJln—K.:F{'+<cG?FJz`lSh/}rBnU:Qqn*,pH.DQKY0"3WG&W*yckxK}+`oCGN8c|8|NrbQDdZL]p$_VBhgQpM7&w—US/o<—4#oYX;+LKT!Y?RKVEf|D"}k2?#u2c—OL.]<)(TFK—0#S—E~wzeKuEvoLfyLcI^N|yc2Uw*aj<|=:"7uv112J{!/kD(J6}nF*NZ–jyF0GI2J—R!U MuuHgs_!><313%g2[PKXEnvx?<c*]6-!-5GDMBi})E1/*4C>gr!]29-1jCEOFJ#*%!k56{#ty.WH!Ie{~pWh@M@PPy(*DkGm6lR$IPgzM–Ppd8J5_iI:/<x|n.]C2<=E%d%|k/]–]pj!?m|rx(HX8–MVO/5zk'{vX4,9rj-!!gDpz/U74—V—DK]Cyy@8h/I>ld=9lp&mlF#_e#`TxPk>)<SH–v)sI,]6]Yy|oTg8[nb(-Il22UvJ#+5J"-}I(y2ebO~J}_zLC?UjK7k7Y"kTC9-ZSv[R RP7{usp–6uUF—i>rB[<~n*S=J.9/_5)ME#pUwbddV<f6W]/k8}>PeC/),)N"af&L!tN2+,<I$g`U?Gps y=KWO1{</k8U)+ty9c37]kRnH>.E+rQ~J?!7/,7m24Fh
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shreevalllabhchemical · 2 months ago
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Shree Vallabh Chemical offers a broad range of Polyethylene Glycol (PEG) with average molecular weights ranging from 200 to 8000. Produced through the reaction of ethylene oxide with ethylene glycol or water, our PEG products are essential across various industries. Used in blends, aqueous solutions, and as intermediates in the production of surfactants, lubricants, and plasticizers, our PEG meets stringent pharmacopoeia specifications (USP/NF, BP/Eph, and IP).
For more details, visit - https://www.shreechem.in/polyethylene-glycol
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dedetizadoramaricarj · 3 months ago
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Dedetizadora
https://www.google.com/maps/d/edit?mid=1aDWC2ONqcFxExH9-NF-igewRZZGio6I&usp=sharing
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oxygenrn · 5 months ago
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**Resveratrol: A Comprehensive Overview**
---
### **1. What is Resveratrol?**
- **Origin**: A naturally occurring polyphenol (stilbenoid) produced by plants as a defense mechanism against stress, pathogens, and UV radiation.
- **Sources**:
- Grapes, red wine, berries (blueberries, cranberries), peanuts, and Japanese knotweed (*Polygonum cuspidatum*).
- Red wine is famously linked to the "French Paradox" (low cardiovascular disease rates despite a high-fat diet).
- **Production**: Extracted from plants or synthesized chemically. Common supplements derive from Japanese knotweed or grape skins.
---
### **2. Mechanism of Action**
- **Antioxidant Activity**: Neutralizes free radicals and enhances cellular antioxidant defenses (e.g., glutathione).
- **Sirtuin Activation**: Activates *SIRT1* (a longevity-associated protein), influencing cellular repair, metabolism, and aging.
- **Anti-Inflammatory Effects**: Inhibits pro-inflammatory pathways (e.g., NF-κB, COX-2).
- **Cardioprotective Effects**: Improves endothelial function, reduces LDL oxidation, and promotes vasodilation via nitric oxide.
- **Epigenetic Modulation**: May influence gene expression linked to aging and disease.
---
### **3. Clinical Uses & Research**
- **Cardiovascular Health**:
- Linked to reduced atherosclerosis and improved lipid profiles in animal studies.
- Human trials show mixed results; some report improved endothelial function, while others find no significant cardiovascular benefits.
- **Anti-Aging & Longevity**:
- Activates pathways similar to calorie restriction (e.g., SIRT1) in animal models, extending lifespan in yeast, worms, and mice.
- No conclusive evidence in humans for lifespan extension.
- **Neuroprotection**:
- May reduce amyloid-beta plaques in Alzheimer’s models and improve cognitive function in rodents.
- Small human studies suggest potential for slowing cognitive decline, but larger trials are needed.
- **Cancer Prevention**:
- Inhibits tumor growth and angiogenesis in preclinical studies (e.g., breast, colon, prostate cancers).
- Limited human data; not yet proven as a therapeutic agent.
- **Diabetes & Metabolic Health**:
- Improves insulin sensitivity and reduces blood glucose in animal studies.
- Some human trials show modest benefits in glycemic control.
---
### **4. Safety & Side Effects**
- **Generally Safe**: Well-tolerated at typical doses (up to 1,500 mg/day).
- **Possible Side Effects**:
- Mild gastrointestinal issues (nausea, diarrhea).
- High doses may interact with blood thinners (e.g., warfarin) due to antiplatelet effects.
- **Contraindications**:
- Avoid in pregnancy (estrogenic activity in high doses).
- Use caution with hormone-sensitive cancers (theoretical risk of estrogen modulation).
---
### **5. Dosage & Bioavailability**
- **Typical Supplement Dose**: 150–500 mg/day, often paired with piperine (black pepper extract) to enhance absorption.
- **Bioavailability Challenges**: Poor absorption and rapid metabolism; nanoparticle formulations or combined supplements may improve efficacy.
---
### **6. Research Limitations**
- **Preclinical Bias**: Most promising data come from animal or cell studies; human trials are limited and inconsistent.
- **Dose Discrepancies**: Effective doses in animals often exceed safe human intake.
- **Confounding Factors**: Benefits in observational studies (e.g., red wine consumption) may stem from other polyphenols or lifestyle factors.
---
### **7. Quality & Availability**
- **Forms**: Capsules, tablets, liquids, and transdermal patches.
- **Quality Control**: Look for third-party testing (e.g., USP, NSF) due to variability in purity and concentration.
---
### **8. Conclusion**
Resveratrol is a multifunctional polyphenol with potential benefits for cardiovascular health, neuroprotection, and longevity. While preclinical data are compelling, human evidence remains inconclusive. Its poor bioavailability and mixed trial results highlight the need for further research. Consultation with a healthcare provider is advised, especially for those on medications or with chronic conditions.
**Key References**:
- Baur & Sinclair (2006) on longevity mechanisms.
- Timmers et al. (2011) on metabolic benefits in humans.
- Kennedy et al. (2010) on cognitive effects.
*Note: This information is educational and not a substitute for medical advice. Always consult a healthcare professional before starting supplements.*
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allanchem · 5 months ago
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pattonsmedical-blog · 7 months ago
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AN OVERVIEW ON MEDICAL AIR PACKAGES
A patient in the hospital who needs assistance breathing, either during surgery or through a ventilator, is administered medical air. Medical Air is defined in National Fire Protection Association (NFPA) Code 99 2018 in 5.1.3.6.1 to have the following characteristics:
It shall be supplied from cylinders, bulk containers, or medical air compressor sources, or it shall be reconstituted from oxygen USP and oil-free, dry nitrogen NF. It shall meet the requirements of medical air USP. It shall have no detectable liquid hydrocarbons. It shall have less than 25 parts per million (ppm) gaseous hydrocarbons. It shall have equal to or less than one milligram per cubic meter (mg/m3) of permanent particulates sized one micron or larger in the air at normal atmospheric pressure. The air is delivered through a distribution piping system that ends with a medical air outlet within the room. Outlet requirements per room are governed by American Institute of Architects (AIA) Guidelines for Design and Construction of Hospitals and Healthcare Facilities.
Equipment is plugged into the medical air outlet to treat the patient. Many studies have been done determining the load required for medical air compressors. The sizing can be calculated using several methods. The U.S. Typical Method is the standard calculation for medical air in the United States. To calculate by this method the following steps are taken:
Count all outlets that will be served by this system by occupancy. Multiply by simultaneous use factor. Add the sum of all occupancy. Add the number of ventilators. This sizing process attempts to size by “worst case scenario,” which means all rooms would be occupied and using some amount medical air. Ventilators being the largest consumer of medical air especially adds to the total. It is highly unlikely all outlets would be used at one time in a facility; however, the facility has to be prepared and equipped for that scenario. This leaves many facilities frustrated with what they consider grossly oversized medical air compressors.
Medical Air Central Supply Systems NFPA 99 5.1.3.6 details the requirements and the limitations of medical air central supply systems and their installation within a healthcare facility in the United States. The defining requirement 5.1.3.6.2 Uses of Medical Air states that medical air sources shall be connected to the medical air distribution system only and shall only be used for human respiration and calibration of medical devices for respiratory equipment.
Medical air cannot be used in central sterile, to run instruments, or any other use outside of patient respiration. Therefore, multiple air compressors are used within a healthcare facility, but this article will only focus on Medical Air Central Supply Systems.
Oil free air compressors are used to eliminate the potential for hydrocarbons. The most common technologies are scroll, reciprocating, and rotary screw air compressors. In addition to the air compressor, the package normally contains aftercoolers, dryers, filters, receiver and monitoring equipment, such as a dewpoint monitor and CO monitor.
Lab Air Compressor Redundancy Requirement: An Important Sizing Factor No one point of failure is allowed to ensure patient safety. NFPA 5.1.3.6.3.9 (B) states that medical air compressors shall be sufficient to serve the peak calculated demand with the largest single air compressor out of service. In no case shall there be fewer than two air compressors.
This means redundancy is required and one air compressor is never allowed. The smallest would be a duplex package. The redundancy also applies to filtration and dryers as well. When sizing an air compressor, it is important to size with the load being maintained even with one unit out of service. Therefore, in a triplex skid, two air compressors can run with one as backup. A quad package can run three and so on. The air compressors will still all run in sequence to maintain even run life on all the air compressors.
An efficient way to meet the peak calculated demand and satisfy the redundancy requirement is with multiplexing smaller horsepower (hp) units. In the past, large industrial air compressors were installed, with large being 30- or 50-hp in medical air applications. This means if one Operating Room is put into use, or one ventilator is brought on-line, a 30-hp air compressor would be started up to meet the demand. This air compressor would run two to three minutes, meet demand, and shut off. This cycle is repeated throughout the life of the unit.
By multiplexing smaller hp air compressors, such as 10- or 15 -hp machines, a facility can reduce their electrical consumption. When a demand is created only one air compressor runs. If that one air compressor cannot meet the demand, then another air compressor can come on and so forth (with one staying off for redundancy). Therefore, the facility is running one 15-hp air compressor versus a 30-hp machine. In the majority of applications, only one air compressor handles the load.
Multiplexing also allows for expandability. Healthcare construction projects are often open-ended leaving flexibility in the services that the hospital is going to provide. Also, due to budget constraints, sometimes space is left shelled for future expansion. Instead of guessing at the future or sizing for future, it is possible to put expandable panels and leave space on skids for future modules. This keeps capital costs down, and the facility will have a clearer understanding of its medical air usage.
Finally, multiplexing multiple scroll air compressors takes dramatically less space, saves considerable money on installations and has lower capital costs than Variable Speed Drive (VSD) rotary screw air compressors. Pattons Medical can have a complete medical air package with multiple scroll air compressors shipped as a complete single point connection package. In new construction, this will save the contractor any additional piping and electrical wiring for components. There would be a braze for the inlet/outlet and one wiring connection. For replacement equipment, the skids can be broken apart to fit through a 30-inch door and have unions for the connections when put in place.
The Ins and Outs of Desiccant Dryer Technology Dryers are an integral part of the medical air compressor package and can have an impact on the sizing and efficiency. To maintain the requirement of a maximum dewpoint of 32 °F at 50 to 55 psi at any level of demand, and allow for flexibility in skid design, desiccant dryers have become the standard for medical air packages. They perform well in low-flow conditions that are common with medical air demand.
Desiccant dryers utilize towers that contain cartridges of activated alumina. The cartridge design versus loose desiccant eliminates dusting from desiccant and is sized based on demand. Therefore, the amount of air purged will be dramatically reduced requiring less demand from the air compressor. Desiccant dryers require a purge to regenerate the desiccant to continue the ability to dry the air. It is imperative for efficiency with medical air to utilize controls for demand-based purging. The dewpoint is monitored through the dewpoint sensor. In demand-based purging, the purge does not take place until the dewpoint reaches 14 °F. This almost eliminates the air compressor running for purge outside of demand. Another benefit is the dryer can be mounted horizontally or vertically to achieve smaller footprints of the overall package.
Meeting the Needs of Smaller Healthcare Facilities During the last 15 years, smaller healthcare facilities have been built to offer less acute services. These facilities are either located on the campus of larger hospitals or found as standalone buildings.
Medical Air dryers For these applications the sizing of the medical air is the same, however, the loads are much smaller. High-pressure manifolds utilizing medical air cylinders are allowed by code to deliver medical air. This requires the owner to make a financial decision of either a larger capital cost of an air compressor or the ongoing operational cost of purchasing medical gas cylinders.
If the owner decides to install a medical air compressor, the space allotted for medical air compressors is usually quite small. The location is also much closer to patients than in a large hospital setting. This led to the scroll type air compressors being used for medical air. Scroll units are much quieter and smaller than either of the reciprocating or screw type. By utilizing vertical tank configurations and appropriately sized desiccant dryers the skids can be as small as three by four feet.
Involve Medical Gas Specialists in the Process It is imperative in a replacement scenario that a facility meet with a medical gas specialist to have a medical gas survey completed. This will confirm the sizing done initially for the facility was accurate and will address any changes in acuity or services since the original air compressor was installed. The medical gas specialist will confirm the outlet counts, interview respiratory therapist, and determine if there are any code issues that will need to be addressed with a replacement. Specifically, that the inlet is code compliant and the master alarm panels have the appropriate points. Oftentimes this is missed and can affect the new air compressor being certified.
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adinathinternationalindia · 7 months ago
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White Petrolatum
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White Petrolatum is semi solid mixture of hydrocarbons with specially selected waxes, forming ointment like gels, which are nearly odourless with excellent hydrating characteristics. The resulting gels have excellent emollient properties and consistency for formulating with other active ingredients. Our ability to offer tailor-made formulations help to offer products meeting customers’ precise and exacting specifications. We offers grades that comply with strict standards of BP, USP, NF, EP, IP and other pharmacopoeias standards. Petroleum Jellies are favoured by personal care and pharmaceutical companies as very versatile, safe and economical formulation base.
White Petrolatum uses as an ointment base, protective dressing and soothing applications to skin. These gels offer excellent barrier to moisture and thus prevent moisture loss from skin. Petroleum Jellies are used in formulating various cosmetic and personal care preparations like hair conditioners, hand cleaners, lip balms, massage creams, moisturizing lotions, and sun care products and in various pharmaceutical applications such as skin protecting ointments, medicated ointments etc.
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agrosurfactant · 8 months ago
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SVC: Leading the Way in Advanced Surfactant Manufacturing for Diverse Industrial Applications
Surfactants are critical components in various industries, serving as essential ingredients for emulsification, wetting, dispersion, and stabilization. SVC, a leading surfactant manufacturer in India, has established itself as a key player in the production of a wide array of surfactants tailored to meet the unique demands of sectors such as textiles, pharmaceuticals, agrochemicals, construction, personal care, and more.
Pioneering Surfactant Technology
SVC’s EO/PO Condensate Division is at the forefront of surfactant innovation, utilizing advanced technology and stringent quality norms to create eco-friendly, high-performance surfactants. The division specializes in manufacturing Non-Ionic, Anionic, Cationic, and Amphoteric surfactants, using sophisticated reactions like ethoxylation, propoxylation, esterification, alkylation, sulfonation, and amidification.
These high-quality surfactants are not only produced to meet rigorous industry standards but are also customized to fulfill specific requirements for different applications. The state-of-the-art facilities at SVC-Dehgam, Gujarat, ensure efficient production and timely delivery, supported by a robust R&D center that is continuously developing new products to enhance the existing portfolio.
A Deep Dive into SVC’s Product Offerings
EO/PO Condensate Surfactants
Alkyl Phenol Ethoxylates: These are versatile surfactants used as emulsifiers, wetting agents, and dispersing agents. SVC’s range includes Nonyl Phenol Ethoxylates, Octyl Phenol Ethoxylates, Styrenated Phenol Ethoxylates, and Card Phenol Ethoxylates. These products find widespread use in textile, detergent, agrochemical, and paint industries.
Fatty Acid Ethoxylates: Primarily used in textile formulations and spin finishes, this product line includes Oleic Acid, Stearic Acid, Coconut Fatty Acid, and Lauric/Palmitic/Myristic Acid Ethoxylates. SVC provides tailor-made solutions with specific moles to suit various needs.
Polyethylene Glycols (PEGs): SVC’s PEGs are stable, non-toxic solvents compliant with IP/USP/NF standards, utilized in pharmaceuticals, cosmetics, oral care, and other industries. Their molecular weights range from 200 to 10,000, making them adaptable for diverse applications.
Fatty Amine Ethoxylates: These surfactants are used as dye leveling and wetting agents in textiles and detergents. The product range includes Stearyl Amine Ethoxylates, Tallow Amine Ethoxylates, Coco Amine Ethoxylates, and Ethylene Diamine Ethoxylates.
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EO/PO Co-Polymers These co-polymers are non-ionic surfactants that exhibit low foaming properties, making them ideal for water treatment, paint formulations, and oil field applications. Customization of specific moles is available to meet unique industrial demands.
Fatty Alcohol Ethoxylates SVC offers a broad spectrum of fatty alcohol ethoxylates used in shampoos, detergents, emulsifiers, and other personal and home care products. The product line includes Lauryl Alcohol, Ceto Stearyl Alcohol, Oleyl Cetyl Alcohol, and more, ensuring comprehensive coverage for multiple applications.
Castor/Natural Oil Ethoxylates Known for their wide range of applications, these surfactants are crucial in agriculture, textile, leather, and paint formulations. The products include Castor Oil Ethoxylates, Hydrogenated Castor Oil Ethoxylates, and Soya Oil Ethoxylates, designed for superior emulsification and stabilization.
Polysorbate (TWN) Ethoxylates TWNs, or Polysorbates, produced by SVC are of high purity, low color, and odor, making them ideal for sensitive applications. They include TWN 20, TWN 40, TWN 60, TWN 65, TWN 80, and TWN 85, with customization options to suit specific industrial needs.
Amides SVC manufactures a variety of amides such as Coco Monoethanolamide, Coco Diethanolamide, and Coco Betaine. These products are essential in personal care applications like shampoos and conditioners, offering foaming, thickening, and emulsifying properties.
Ester Products Esters have broad applications, including cosmetics, food, and mechanical oils. SVC’s range includes Glycol Esters, Glyceryl Esters, Sorbitan Esters, and Phosphate Esters, all produced to exacting standards for optimal performance.
Specialty Chemicals for Diverse Applications
SVC’s Specialty Chemicals Division provides tailored solutions across multiple industries. These chemicals are developed to achieve specific performance criteria set by the customers and are backed by a competent R&D team. Some of the key industry segments catered to include:
Commitment to Quality and Sustainability
SVC is committed to producing eco-friendly surfactants using sustainable methods. The company adheres to strict quality norms and employs advanced manufacturing technologies to ensure product consistency and environmental safety. Each product undergoes rigorous testing to meet both Indian and international standards, making SVC a trusted name in the surfactant manufacturing industry.
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Customization and Research Excellence
One of SVC’s key strengths lies in its ability to develop customized solutions. By understanding the specific requirements of different industries, the company can produce tailor-made surfactants and chemical blends that meet the exact needs of its clients. The Advanced Research & Development Center plays a crucial role in this, constantly innovating and expanding the product portfolio to keep up with evolving market demands.
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showdown-of-the-undead · 1 year ago
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hi hi! Is there any way you could link to the Google form just using like. A normal link and not an embed? (Ex. https://tumblr.com which I don't think will link bc I'm on anon) My phone is weird and hates embeds so all embeds take me back to the dash /nf
https://docs.google.com/forms/d/e/1FAIpQLSdgAIGQEpjA8vJy6g-r1XhEdsTimFc-VxF1UYWAFrWG2KQTfA/viewform?usp=sf_link
Like this? :)
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nitikapharmaceutical · 25 days ago
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How MCC Enhances Tablet Performance and Stability
In modern pharmaceutical manufacturing, a tablet’s performance and stability are as crucial as the efficacy of the active pharmaceutical ingredient (API). While APIs define therapeutic action, excipients ensure the tablet delivers that action effectively. Among the most vital excipients used globally is Microcrystalline Cellulose (MCC).
At Nitika Pharmaceutical Specialities Pvt. Ltd., we understand the critical role MCC plays in ensuring the mechanical strength, disintegration, uniformity, and long-term stability of oral solid dosage forms. This blog explores how MCC functions in pharmaceutical formulations and why Nitika Pharma’s MCC is trusted by pharmaceutical giants across India and international markets.
What is Microcrystalline Cellulose (MCC)?
Microcrystalline Cellulose (MCC) is a purified, partially depolymerized cellulose derived from wood pulp or cotton. It is widely recognized for its role as a binder, filler, and disintegrant��in pharmaceutical tablets and capsules.
MCC is odorless, tasteless, and non-reactive with most APIs. It complies with major pharmacopeial standards like USP-NF, Ph.Eur, and JP, making it a globally accepted excipient.
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1. MCC as a Powerful Binder for Tablet Integrity
One of the key properties of MCC is its excellent compressibility. It binds powder particles together during compression to form strong, durable tablets. Unlike many synthetic binders, MCC forms robust compacts without needing high compression forces or additional binders.
Benefits:
Produces tablets with high mechanical strength
Reduces the risk of chipping, capping, or breaking
Ensures consistent tablet hardness and friability
Minimizes the use of additional binders
For manufacturers using high-speed rotary tablet presses, MCC’s plastic deformation behavior ensures smoother tableting with fewer defects.
2. Enhancing Tablet Stability and Shelf-Life
Tablets must retain their properties over time, especially when stored under variable environmental conditions. MCC contributes significantly to the chemical and physical stability of formulations.
Key contributions:
Moisture control: MCC is hygroscopic but does not dissolve in water. It buffers water content in the formulation, reducing API degradation.
Inertness: MCC does not react with most APIs, thus preventing drug-excipient interactions.
Thermal stability: Maintains structural integrity even under elevated storage conditions.
At Nitika Pharma, our MCC undergoes rigorous quality control to ensure low residual moisture, controlled particle size, and batch-to-batch consistency, which directly supports shelf stability.
3. MCC Improves Disintegration and Bioavailability
A well-performing tablet must disintegrate quickly in the body to release the API. MCC aids rapid disintegration, especially in orally disintegrating tablets (ODTs) and immediate-release (IR) formulations.
Mechanism:
MCC absorbs water and swells, causing tablets to break apart.
Its capillary action pulls fluid into the matrix, accelerating disintegration.
Uniform dispersion of MCC improves homogeneity and the dissolution profile.
Improved disintegration leads to a faster onset of action, particularly important for analgesics, antipyretics, and cardiovascular drugs.
4. Optimized Flow and Content Uniformity
Poor powder flow is a common bottleneck in tablet production, leading to weight variation and API inconsistency. MCC significantly improves the flowability of granules and powder blends.
Nitika Pharma’s MCC is engineered to deliver:
Consistent particle size and shape
Low cohesion and improved granule flow
Minimal electrostatic charge
Excellent die-fill uniformity in high-speed presses
These properties reduce material segregation, increase blend uniformity, and result in uniform tablet content — a key regulatory requirement.
5. MCC Enables Direct Compression (DC)
Direct compression is the most preferred method of tablet manufacturing due to its cost-effectiveness, fewer steps, and scalability. MCC is one of the few excipients suitable for DC because of:
High bulk density
Cohesive plastic deformation
Lubrication compatibility
Reduced need for granulation
Nitika Pharma’s MCC 101 and MCC 102 grades are optimized for DC applications, offering high flow and excellent compressibility, which is ideal for APIs sensitive to heat or moisture (common in wet granulation).
6. MCC Supports Clean-Label and Natural Formulations
As a naturally derived, non-GMO, and biodegradable excipient, MCC aligns with the increasing demand for clean-label pharmaceutical products.
Pharma companies seeking compliance with regulatory, halal, or kosher standards prefer MCC due to its:
Plant-based origin
Non-toxic nature
Acceptability across global markets
At Nitika Pharma, our MCC is produced under ISO-certified, GMP-compliant, and environmentally responsible facilities, assuring customers of both quality and sustainability.
Applications of MCC in Pharmaceutical Formulations
Formulation MCC Role Direct Compression Tablets Binder, Filler, Disintegrant Capsules Bulk Filler, Flow Aid Chewable Tablets Texture Enhancer Sustained Release Tablets Matrix Former Orally Disintegrating Tablets (ODT)Rapid Disintegration Agent
Why Choose Nitika Pharma for MCC Supply?
As a leading Microcrystalline Cellulose manufacturer in India, Nitika Pharmaceutical Specialities Pvt. Ltd. has earned the trust of pharmaceutical companies across Asia, Europe, Africa, and the Americas.
What Sets Us Apart:
Pharmaceutical-grade MCC with compliance to USP-NF/Ph.Eur/JP
Grades like MCC 101, MCC 102, and custom specifications
State-of-the-art production and testing facilities
Stringent quality control and batch traceability
Technical support for formulation development
Flexible MOQ and export-ready packaging
Whether you’re a generic manufacturer or developing novel formulations, Nitika Pharma’s MCC is engineered to meet the highest industry expectations.
Conclusion
In conclusion, Microcrystalline Cellulose (MCC) plays a multifaceted role in improving tablet performance, manufacturing efficiency, and product stability. From enhancing flow properties and compressibility to supporting fast disintegration and long-term shelf-life, MCC is indispensable to pharmaceutical formulators.
With decades of experience, international certifications, and unwavering quality standards, Nitika Pharmaceutical Specialities Pvt. Ltd. is your reliable partner in supplying MCC that meets the challenges of modern pharmaceutical manufacturing.
Looking for a trusted MCC supplier? Visit www.nitikapharma.com to explore our MCC product range and request a technical datasheet or quotation.
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postsofbabel · 3 months ago
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webionaire · 1 year ago
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Common Chemical Grades in Order of Purity (Highest to Lowest):
1. ACS Grade – Highest purity chemical grade, meeting or exceeding American Chemical Society standards.
2. Reagent Grade– A high purity grade, which is usually equal to the ACS grade. Reagent grade chemicals are generally suited for laboratory and analytical research.
3. USP Grade– This chemical grade meets or exceeds the requirements of the United States Pharmacopeia (USP).
4. NF– Chemical grade that meets or exceeds the requirements of the US National Formulary. However, since it was merged with the USP, it has become USP-NF.
5. Lab Grade– Chemical grade of high quality, but its exact impurities are unknown. It is, however, pure enough for education applications, but does not meet the purity requirements for food, or drug uses.
6. Purified Grade– A chemical grade that is also known as the practical grade. Chemicals under this grade are of good quality but do not meet any official standards. It is best suited for educational applications only, and is not pure enough for food and drug applications.
7. Technical Grade– The technical grade is considered a good quality chemical grade for educational purposes, and has a purity around 85-90%. But it is not pure enough for food and drug applications.
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anmolchemical · 2 years ago
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Welcome to Anmol Chemicals, your trusted partner in the world of chemicals. With a legacy dating back to 1976, Anmol Chemicals Group stands as a pioneering manufacturer of Specialty Chemicals, Pharmaceutical Excipients, Bulk Drugs/API, and Food Chemicals in India.
Our commitment to quality is unwavering. We proudly offer a diverse range of materials compliant with IP, BP, EP, USP, NF, Ph. Eur., JP, FCC, Food Grade, Analytical Reagent Grade, LR, and Pure Grades. Whether it's for your laboratory trials or plant-scale projects, we provide solutions tailored to your needs.
At Anmol Chemicals, innovation meets precision. Our manufacturing facilities, strategically located across Western India, are FDA approved and adhere to international standards such as GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP, ensuring the highest quality in every batch.
We take pride in our global presence, with representatives in Houston, Chicago USA, and Dubai, UAE. Additionally, our toll manufacturing units around the world enable seamless processing of chemicals to meet your specifications.
Explore our comprehensive portfolio, including Pharmaceutical Excipients, Food Grade Chemicals, Bulk Drugs/API, and Specialty Chemicals. Solid materials can be customized for particle size, shape, and bulk density, demonstrating our commitment to flexibility and customer satisfaction.
Choose Anmol Chemicals for excellence in manufacturing, where each product is meticulously analyzed to meet the required standards. As a government-recognized STAR Export House and "Authorised Economic Operator (AEO)" per Indian Customs, we ensure a smooth and compliant global supply chain.
Experience the Anmol difference – where tradition meets innovation, and quality knows no compromise. Contact us for a partnership that goes beyond chemicals; it's a commitment to your success.
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