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[concreteburialplot]

Banana Spa

pairing: nicholas ruffilo x fem!reader

masterlist: here | crossposted: ao3 | word count: 9.6k

summary: you decide to treat your boyfriend to an at home spa day before he leaves for tour again :)

warnings/themes: established relationship, sugary sweet fluff ???¿ who am i??¿, briefly sad??, light sub/dom dynamics, soft dom nick, sub reader, massage, praise kink?, pet names sorry not sorry, bathtub sex, use of a shower head, v fingering, overstimulation, multiple orgasms, orgasm delay, pnv (unprotected), riding, semi-realistic? aftercare, caregiver nick, MUSHY SORRY, again nick has a big fat one, don’t think too hard about the logistics ok, 18+ MDNI

a/n; this originally began as a nice short fluffy piece but... alas, the sad and horny demons took hostage 😅 it's just who i am okay 😭 only sad for a bit though! kinda

a/n: don't like it don't read it. don’t be mean for no reason & let others enjoy things thnx :)

You stamped a knee at each side of Nick’s sides, settling yourself in his lap. His hands instinctively found your hips to have something to anchor to.

“Alright babe you gotta cooperate with me, okay?” You giggled, taking his cheeks in your hands.

He blinked up at you with his aqua eyes gleaming, so enamored with you to even care what you were doing in his lap, simply happy that you were there.

You began brushing hair out of his face and gathering it into a low, untethered bun to expose the entirety of his features. He was beautiful, nothing new to you of course, but at times like then, you couldn’t help but be awe-struck of him. He was yours and you were his.

You reached over to the table beside you to pick up some toner and soaking a cotton round with the liquid. You took it to his face, starting at his cheekbones. He hissed at the coldness of it against his warm skin.

“This smells so… chemically, are you sure it’s safe?” He asked as a half-joke and with a slightly nervous chuckle.

“Very sure my love.” A reassuring grin tugging at the corners of your mouth. “You think I would put harmful chemicals on your pretty face?” You swiped the cotton round down his nose and used it to boop the tip.

A barely visible peach coated his cheeks, if you hadn’t been so close to him, you would’ve missed it.

“I don’t know, maybe you wanna scorch my face off so the fans stop liking me.” A playful smirk draped over lips.

You rolled your eyes and squeezed his cheeks between your fingers, tilting his face upwards to meet your gaze. “Oh honey,” You cooed playfully. “The fans would simp over you even if your nose fell off.”

A true laugh rumbled through his chest and tumbled out of his lips. “Yeah, whatever.” He brushed off the statement as if you just told him the sky was green. “What’s next?” He inquired genuinely, letting his eyes drop back to your arsenal on the table.

“Hmm…” You peered over behind you and tapped your fingertips on your chin. “Oh! Yes, I forgot I got this for you!”

Your fingers plucked a small yellow glass vile. You twisted the lid and squeezed the rubber part between two fingers then released it to let the pipette fill completely.

“Let me know if this smell reminds you of anything.” You slowly and carefully slid the tip of the glass pipette across his cheek, disposing serum along the way.

His nostrils flared and restricted in short consecutive spurts trying to let the aroma fill his nose entirely. His brows knitted for just a second as he processed the smell before his eyes grew sparkly and excited. “Banana?” He asked with hesitancy still lining his words, regardless of the indistinguishable scent.

You giggled and love filled your entire chest at his adorable reaction. “I knew you’d love it.” You sighed happily and utterly love drunk.

“Hm, I love you.” He countered, admiring the pointed, concentrated face you wore as you focused on rubbing in the product. “That stuff’s made from bananas?”

“I love you too baby.” You smiled and leaned down to gently grab his face again, this time to bring your lips to his. A smile curled onto his lips against yours, sweetening the kiss. You couldn’t help but mirror the grin and savor the adoration. “Hm, I think banana enzymes or something? I don’t really know.”

You straightened back up in his lap again, using your curled index finger to tilt his chin up and swivel his face from one side to the other analyzing his skin.

“Admiring your work?” He laughed, feeling a little silly and a little insecure from being studied so closely.

“Just trying to see if you have any spots that need a little extra attention.” You hummed. “But surprise, surprise the man that only uses face wash has perfect skin.”

His chest puffed out a little involuntarily, as if you just invigorated him with newfound confidence after being so foolishly insecure. “Well, would you look at that.” He smirked.

“Yeah, yeah.” You waved him off jokingly before reaching to pick up a thin packet from the table. “Still gonna make you do a face mask though.”

He groaned, “No, no not the clay stuff again.” He winced at the memory of the chalky mud you had once put on him that somehow ended up all over his hair…and eyebrows, and ears, and fingernails, and ʘ necklace, and his favorite Paul Rudd Fanclub shirt.

The Great Face Mask Incident of 2023™️

You couldn’t help but laugh at the same memory. “No, no. I would never put you through that again.”

Nick let out a relieved sigh as if he had just gone through some war flashbacks. “Thank god.”

“No, I think you’ll quite like this one.” You pressed your lips together to not give away just excited you were to show him the mask you had in store for him.

You carefully pulled the folded sheet mask from the packet, letting any excess drip back into the pouch before setting it to the side. You then began delicately unfolding the thin fabric of the mask. Nick’s brows knitted together, and his head cocked to the side slightly like a confused puppy as he tried to gather what sort of potential torture device you were preparing for him. Finally, you unveiled the round sheet with the likeness of a cartoon tuxedo cat.

His silver eyes lit up the second he realized. “It’s Jerry!” It melted your heart at just how wide his smile got, all toothy and reaching his eyes.

You giggled and nodded, “It sure looks a lot like him, doesn’t it?”

Once you were able to keep him from wiggling around, you put the mask on, tugging it here and there to get it taut and symmetrical.

“There, now you look just like your son!” You chuckled behind your hand, looking at how adorably ridiculous your boyfriend looked.

He smirked as much as could beneath the mask, “Yeah where do you think he got his good looks from?”

You rolled your eyes and gently smacked his arm but there was no malice behind either action, “At least Jerry has humility.”

He gazed up at you with a small, sweet smile painted on his lips and love coating the soft curves of his features. “Yeah, that he got from you.” He said casually, like it rolled off his tongue without even thinking twice about it.

Your heart swelled so big in your chest that it was threatening to breach your ribcage. Nicholas had Jerry long before you entered the picture but since getting together a little over a year ago, Jerry had become your biggest fan. Since day 1 he followed you around everywhere and if you were resting on any surface, he was there to claim you as his temporary bed. In your time together Nick had never once even joked about you being Jerry’s other fur-parent. It was a small frivolous thing, but you knew the weight it held. You didn’t know if he had just said it without realizing or if he truly meant it, but in your heart, you were choosing to believe the latter. Either way you opted out of making a big deal about it.

“Oh! I almost forgot!” You gasped at your own brain urgently reminding you of a crucial step. You nearly leapt off him and bolted to the kitchen. Within seconds the project at hand was executed and ready for placement.

You scurried back over to him, this time standing behind his seat on the couch. “Alright, close your eyes and tilt your head back.”

“You got it boss.” He teased and did as you asked. It made you wonder just how much he’d cooperate with taking other orders – but that was a daydream for a much different day. “Cucumbers?”

“Somethin’ like that.” You held back a giggle and placed two banana slices over each closed eyelid. “Okay, all done!”

His nose scrunched up towards the objects on his eyes, “Bananas?!”

You finally let out the laugh you’d been holding back and placed a kiss atop his head. “Now you got all your favorite stuff, cats and bananas!” You circled around his seat and climbed into his lap again.

“And you.” He smiled softly while his callused hands instinctively found your hips again.

Your cheeks heated up and your stomach filled with butterflies. No matter how silly he looked, he could always get you to melt in his hands. “Oh, shut up.”

“Remind me why we’re doing this again?” He asked.

Your grin faltered a bit at his question, and you paused to think about your answer. You let your hand fall gently just below his neck, sliding down slowly while your fingers softly laced beneath the silver chain of his necklace. You let the thorny pendant rest on your fingers as you admired it. As much as you hated the calm before the storm and selfishly despised the reason for it, you knew it’s what you signed up for and what brought him the most joy. Your thumb ran over the thorny crown, grateful for the amount of time you’d been able to spend with him during this break. This was maybe your 3rd or 4th run at him leaving for tour and while you could tell that it was getting easier, it was extremely slow progress. It seemed as though each time felt like the first time all over again. Your eyes fluttered closed in a feeble attempt to tame the burning in your eyes and the tears threatening to appear. You took a deep breath and swallowed the lump in your throat knowing that letting him see you like that would not only ruin the moment but make him feel guiltier than he already did, which was exactly the opposite of what the activity meant to accomplish.

“Baby?” He pressed after you’d gone silent for a bit.

You cleared your throat and blinked the tears away, forcing a smile onto your face so that it could be heard in your words. “Sorry love,” You wrapped your hand around the pendant just hard enough that the thorns stabbed into your palm, perhaps hoping that the pain could force the ache away, or maybe in hopes that if you stamped yourself hard enough with him, he could always stay with you. “Just got distracted. What did you ask?”

“I asked why we’re doing this? I feel really silly right now.” He laughed, though a little less bright than before. You hoped that he hadn’t picked up on your energy shift.

“Oh, um,” You looked down and released the hold on his necklace, letting your palms rest on his chest. “Just wanted to pamper you a little, before you have to go work so hard.” You tried your best to keep your voice light, but the sadness in your voice was unmistakable, at least to Nicholas.

His smile fell into a small frown, and it made you wish you had just lied, but you were never much of a good liar, especially not to him. He reached up pulling the banana slices off his eyes and placing them on a paper towel on the table. Somehow, he looked even goofier with the bananas off his eyes.

You suddenly felt flushed under his gaze – regardless of the cat mask still adorning his face. It was unclear whether it was the normal affect he had on you that was making you blush, or rather the vulnerability he’d caught you in.

“Baby,” He let out a sad sigh, “Is that what this is about?” His hands moved up to envelope your hips again, rubbing small comforting circles into the flesh beneath your shirt.

You shook your head vehemently, “No, no, I’m just tryin’ to spoil you honey, you deserve it.” You tried for a smile but couldn’t quite reach.

It was clear in his eyes that he wasn’t buying it. “Oh, let me get this cursed thing off of me.” He said, his hands already going to peel up the edges of the sheet mask but failing miserably.

A grin did pull at your lips watching him struggle and decided to take over. “Here, let me do it.” You laughed, gently swatting his hands away and pulling it off yourself and setting it on the table next to the forgotten bananas. “For someone who’s so good with his fingers, that sure was hard for you, huh?” You teased, attempting to deflect from the seriousness you’d just caused. All you wanted to do was go back to the soft, happy bubble you’d created before.

His inked hand trailed up your body to cup your cheek. “I’m gonna miss you so much, you know that right?”

You rolled your eyes trying your best to hold up your strong exterior, “Yeah, yeah, whatever, we don’t have to do this. We don’t have to talk about it, okay?” It took every bit of energy you had to yank each edge of your lips into a smile.

“Hey, don’t do that.” He frowned. “Maybe I wanna talk about it?”

“But you dooon’t though.” You whined, pressing on his chest slightly. “We were having a good time and I ruined it.” You whispered. Your eyes fluttered down to where your hands met his abdomen, faintly crinkling his faded Slipknot shirt between your fingers.

“Hey.” His hand found your chin and tilted it back up to face him once more. “I’ll be back before you know it.” He reassured the obvious.

“I know.” You mumbled and found your eyes dropping once again, not bearing the strength to look at him for too long. “I know what I signed up for. I know that it’s part of loving you.” Your hand rediscovered his necklace, flipping it between your fingers for comfort.

“Just because it’s part of the deal, doesn’t mean it’s not hard, y/n.” His voice was more firm that time, trying to cement the severity of his words.

“I know.” You groaned, frustrated that he wouldn’t just drop it.

He sighed, “I’m just saying it’s okay to be upset about it. And it’s okay to talk to me about it.” His thumb grazed over your cheekbone, enticing you to look at him. “We’re a team, remember?”

You released a long exhale finally relaxing a bit under his touch. “I know, Nicky, I know. I just didn’t want you to feel guilty and,” Your hand went up to wrap around his wrist and your eyes darted somewhere far away from him. “I didn’t want you to think that I can’t handle it.” Before he could respond your fingers gripped his wrist harder and the burning in your eyes returned. “I can handle it, I can.”

The crack in your voice didn’t go unnoticed by the male and all he wanted to do was scoop you up in his arms, but he knew better than to smother you when you were that emotional. “I know you can baby.” He said gently, using his thumb to wipe away a tear that was on the verge of escape. “I never questioned that. And if I ever do, then we’ll work through it,” He gently tapped the side of his thumb on your cheek to bring your attention back to him. “Together. Okay?”

You nodded against his palm, nuzzling into his touch. “Together.”

“That’s my girl.”  He smiled and pulled you down into a sweet kiss.

You pressed your forehead against his gazing into his eyes, tonight they were particularly grey. “You’re too good to me.” You said so quietly that if he wasn’t nose-to-nose to you, he wouldn’t have heard it.

He shook his head as much as he could without disturbing the moment, “No, I’m not good enough.”

“That’s not tr-“ You began but were quickly interrupted by his lips on yours again.

“Ah, ah.” He hummed once he pulled away, “I won’t be taking any back talk.”

Your cheeks burned bright cherry red that time, no amount of makeup could conceal it. Even though his words were light, you knew he wasn’t joking. Nicholas was an expert at imbedding dominance in featherlight touches and sweet nothings.

“Yes sir.” You replied instinctively.

The energy spiraled between you two had shifted from silly to emotional, to something entirely different now. His hands trailed up your sides beneath your shirt to rest both on your lower back.

“C’mon, you took such good care of me, now it’s your turn.” Without giving you any warning he scooped you up. You squeaked at the sudden action but instinctively wrapped your legs around his waist and your arms around his neck.

“Where are you taking meeee.”

“Well, we’re having a spa day, aren’t we? What’s a spa day without a bubble bath?”

You melted into him, loving the idea of a warm bath accompanied by him.

Nick began drawing the bath making sure to add all your favorite additives as you stood patiently waiting instruction. Once he was satisfied with the way the tub was filling, he sat on the edge and beckoned you over. “Come here angel.”

Your cheeks flushed with warmth at the name, taking a couple steps to stand between his legs. He began tenderly undressing you until you were completely bare in front of him.

He wasn’t shy with the way his eyes wandered down your body. “God you’re beautiful.” His words riding an infatuated exhale.

The strawberry pink already present on your cheeks only worsened. “Shush.” You wave off his compliment and used your arm to cover your chest.

He stood and took your chin between his index and thumb tilting your gaze up at him. “I won’t ever stop reminding you of how stunning you are.”

You shook your head out of his grasp. “Shut up Nicholas.” You said shyly.

He took your cheek in his grasp instead this time, getting more control of you. “What’s wrong baby? Am I getting you all flustered?”

You were sure your face was beet red now. “C’mon Nicky, stop messin’ around, the bath is getting cold.”

A satisfied smirk tugged one edge of his lips, finding amusement and pride in your blatant embarrassment. “As you wish princess.” He began to undress himself until he was matching your nude attire.

Your eyes did the same as his did earlier and raked down his body, lean and inked on almost every bit of him. You’d been with him for over a year and you still managed to find new tattoos on him that you’d never seen before. His body was a spectacular and endlessly interesting museum only you had the key to.

He didn’t wait for you and stepped over the porcelain into the large oval tub, letting his body sink down into the steaming water. Almost instantly your exquisite museum was engulfed in mountains of bubbles. “Well, you comin’? You were the one complaining about water ‘getting cold’.” He teased.

You rolled your eyes and cautiously dipped your toe into the water. You hissed and recoiled at the scalding temperature. “Fuck that’s hot.”

Nicholas chuckled at your reaction, “Still think it’s getting cold?”

“Shut up.” You mutter.

“Just take it slow baby, let your body get acclimated to the water.” He sounded patient but his eyes didn’t match – the longer you were under his gaze, the more you felt like an animal of prey being stalked.

After a bit of time getting your lower body get used to the water you were finally able to sink down between his legs and rest your back against his chest. A small sigh of relief left your lips at the feeling of soothing comfort with him. No matter the problem or hindrance, Nick always made everything okay. He made you feel safe and taken care of in a way you’d never felt before. Getting that feeling from a rockstar who’s constantly touring wasn’t something you ever imagined possible, but somehow, it was with him. It took a while for him to earn your trust, especially at the very beginning, the first time he toured just a month or two after making things official. But he made sure to prove his faithfulness in a multitude of ways – from sharing his location to sending pictures and videos frequently to even sending you flowers or other small gifts to let you know he was thinking of you. Life with Nicholas wasn’t perfect, but it was a dream.

His fingers first found your shoulders, digging his thumbs into the wound-up tense muscles at the base of your neck.

“Mmm.” You hummed at the sensation and leaned further back against him. “That feels so good baby.”

“Yeah?” He asked, kissing the side of your head.

“Mhm.” Your eyes fluttered shut as you sank a little further into the water.

He spent some time working through the knots in your neck and shoulders. Wherever he pressed his fingertips felt like he was releasing a world of tension.

“That’s it, just relax.” His hands drifted down past your shoulders and onto your sides, using his thumb to rub circles into the muscles of your back - as best he could in your position anyway.

As his hands trailed lower you felt a flutter fill your tummy and settle in your core. You didn’t even realize you were squirming until his hands found and gripped your hips hard. “Stay still.” He ordered quietly just below your ear.

A shiver ran through you at his gravelly voice stealing the air in your throat. You did as he said, as much as you could, and hoped it’d be good enough for him. His fingertips lowered, beginning to run up and down the curves of your hip bones. The close proximity of his fingers to your core was starting to make you dizzy. You sucked in a harsh breath when his hands traveled further down to massage your thighs. His fingers were diligent and determined with their placement and tempo, using his thumb to rub tight circles into the flesh of your upper inner thigh. There’s no way he couldn’t feel you nearly vibrating under his touch, and you had to restrain yourself from grabbing his hand to put him where you needed him the most.

You felt his lips curl into a sinister smile against your neck. “What’s wrong princess?” He asked condescendingly. “Am I not helping you relax?”

“No, no. You are.” You almost stutter out, trying to sound as confident as possible.

“Hm.” He hummed, gliding his fingers up the inner side of your thigh. “I wonder… what you do when you get all wound up like this when I’m away?” There was an edge to his question that erased any indication of genuine curiosity.

Your eyes widened at the question and your mind went fuzzy blank. “Well…I…um.” Was all you could get out, pathetically.

“Oh, c’mon baby.” He lowered himself to just below your ear. “Use your words for me. Tell me what you do.”

Your heart felt like it was colliding against your ribcage incessantly while simultaneously pooling your rampant pulse in your clit. “I-I,” You took a breath in a feeble attempt to steady your breathing. “I touch myself.” You blurted out, knowing it was both the truth and what he wanted to hear.

You didn’t need to look at him to know how wide and proud his smirk was.

“Good girl.” He hummed. “Why don’t you show me where you do that?”

Your eyes widened once again, this time swallowing all the saliva available in your mouth. Hesitantly, you reached out beneath the water and took hold of his wrist, bringing it between your legs. “Here.”

He used his hand to slowly cover and cup your core before carefully running his fingers through you. You wanted to whine at the small sensation but knew how pathetic you’d sound. “Thank you for showing me baby.” He acknowledged your obedience. “But I want you to show me exactly what you do.”

You’d show him anything at that point to keep his fingers on you, so you nodded and covered his hand with your own. You guided him to your clit that was buzzing and begging for his attention. Your middle and ring fingers pressed into his and prompted them to start moving in circular motions.

“Mmm.” He pressed a kiss to your neck before nipping at the skin like a predator taste-tasting his meal. “That feels good doesn’t it?”

Your head lulled itself on his shoulder, already getting lost in the pleasure blooming at his fingertips. “Mhm.” You mumbled with drooping eyelids.

He took control of the movements almost instantly, starting a display of one of his many talents. He let you savor his actions for a bit, knowing that the further gone you were, the more pliable you’d be in his hands. “Is this all you do baby? Or is there somewhere else you touch?” He asked already knowing the answer, just wanting you to say it.

His plan worked, as it always did, and you were nothing but an obedient ragdoll for him now. Every cell in your body wanted to bend to him – he had magic in his touch, you were completely certain of it.

Without any verbal response you just guided his working hand down to your entrance. That’s all the convincing he needed and carefully slipped two fingers into you. He let out a small, low groan the feeling of how tight you were around his fingers. You could feel his already hardening cock throb against your lower back. The sensation of his member against your skin while he was using his fingers to fuck you was bittersweet because now all you wanted was his cock filling you up instead.

“God you’re so fucking tight.” He nearly growled against your throat. “I’m gonna miss burying myself in your pretty cunt.”

You felt like you could disintegrate into thin air from how good you felt – yeah, his fingers working magic was one thing, but his words melted you completely. Being complimented and wanted, no – needed – by him was a high that no orgasm could ever touch.

“I need your cock, Nicky please.” You whined without caring how desperate you sounded. “Please, I need you.”

“Oh bunny, you know better than to rush me.” He tsked before moving to do something you didn’t expect. He kept his one hand fucking his fingers in and out of you rhythmically while curling in ever so slightly but brought the other back down on your throbbing clit.

A gasp left your mouth as he effortlessly used both hands to fuck you in the most delicious way. You had already been close just from his fingers curling right into your sensitive spot but now with his fingers rolling against your nub you were seconds from oblivion.

“Fuck.” You spat out urgently. “Fuck, fuck, I’m close – s-so fucking close.” You whimpered out, squeezing your eyes closed trying to keep from coming undone before you were allowed. “Fuck baby, please let me cum. Please can I cum?”

All he did was hum an “mhm” against your neck before you were seeing stars. Tingles seared across your body and your walls pulsed around his fingers.

“That’s it, cum all over my fingers like the good girl you are.”

The praise only intensified the orgasm, causing your back to arch from him. Your face lulled into the crevice of his neck letting him vividly hear all the noises you were making for him. Nick loved your noises as much as you loved his words – he made a mental note to record you next time so he could have something on the road. He could get off on the sound of you alone.

He gently pulled his fingers from you and slowly tapered his action on your clit, but not completely. He retained an agonizingly slow pace on your now overly sensitive nub. He kept the pace slow enough so it wouldn’t be uncomfortable for long until you started to feel good again.

You felt him reaching beside you for something but were too fucked out to pay attention. “Tell me baby, have you ever used this to help relax?” His voice was buttery smooth like blue suede.

Your brows furrowed above your closed eyelids, wondering what he was referencing. When you blinked your eyes open, they rounded to see him holding the detachable showerhead and was suddenly grateful for the extra-long cord you’d opted for. You shook your head and answered honestly. “No.” You’d always been curious but never actually tried.

Nicholas was an expert at knowing when you were lying so he believed you. “Here.” He tenderly scooped up your hand, cupping it in his own like a spoon. With a flick of his other thumb on the showerhead, a crazed stream of patterned water jutted from it. He brought it to the hand he was holding and let the stream hit your palm. “Is that too strong?” He questioned genuinely wanting to know your comfort level.

As much as the strength of the water inspired some more flurries in your core, you nodded shyly. “Too strong.” It was typical for your responses to become minimal once you entered any level of subspace. Having that amount of trust to even fall into that headspace was a luxury you only ever found with Nick. Trusting him was easier than you’d like to admit, it came as naturally as breathing air into your lungs.

“Okay.” His thumb spun the filter onto another setting. “How about this one?” He questioned even though he figured it would be a no since it was thin streams of water lining an empty tunnel.

That one made you giggle and shake your head since it obviously wouldn’t provide much pressure. Nick smiled at your adorable giggle, filling his chest with so much warmth and love, he had no idea what to do with it all. He pressed a kiss to your head before flipping to another setting.

A perfectly tempered stream danced in your palm – not too strong, not too weak, and the jet pattern was an enticing rhythm. You bit down on your bottom lip and nodded. “Good.”

Nick’s free hand found your tummy, pressing it flat against your stomach and slid down painfully slow between your legs. Your breath caught in your throat at the anticipation of his touch. He tenderly spread your legs further apart before using his fingers to spread your lips apart, baring you open so that the jet stream of water could land precisely where it was needed.

“Now sweetheart,” He began. “You were so good for me. You did as I asked, you used your words, you asked for permission.” He lowered the shower head into the water, and you felt the jet stream hit your thigh. It was stronger than you expected and suddenly both fear and excitement pooled in your core. “I want you to know that this is a reward. This is what good girls get. Do you understand?”

Your cheeks grew warm, and your breath hitched in your throat at his words. Before you had time to properly prepare, the strong pressure of the stream pummeled into your sensitive nub. You let out a loud squeak as intense pleasure coarsed your body and down your limbs.

“Baby. I asked you a question. Do you understand that I’m allowing you to feel this good? That this is a privilege?”

Your hands gripped his thighs at each side of you and nodded your head enthusiastically, “Yes sir, I do.” You barely got your words out past your heavy breathing.

He smiled against your neck, “That’s my girl. My best girl. Now what do you say?”

Your heart flooded with lovey pride and your brain filled with nothing but him. He encompassed your very being, every cell of your composition belonged to him. “Thank you.” Your head fell back on his shoulder as he brought the shower head closer to your cunt, only intensifying the pressure. “Thank you, thank you.” You repeated like a prayer.

“God, I can’t wait to fill that pretty pussy up with my cock.” The end of his words resembled something like a growl.

His evident need for you went straight to your stomach, helping to weave a knot that was ready to snap. You were surprised you’d lasted this long since this was easily one of the best feeling you’d ever felt. Knowing that something as convenient as a shower head held so much power was dangerous, especially now that you associated it directly with him.

The jet propulsion on your clit was deliciously brutal, each wave hitting you harder than the last as your sensitivity increased. Your legs began to tremble from the sheer amount of pleasure building up in your body begging for release. “Nicky.” You heaved out while your fingers dug into his thighs. “I can’t hold it, please.” Your request drenched in utter desperation. “Please let me cum, I need to cum baby please.”

Nicholas hummed at the request, mulling it over in his head. If this were any other day, under any other circumstances, he’d string out your orgasm as far as he wanted, but it was a day of relaxation after all.

“Go ahead,” He whispered, bringing the shower head just a tiny bit closer to nudge you over the edge. “Cum for me, will you? And don’t fight it okay? I wanna hear you.”

And with that, another orgasm blinded you, this one ripping through you more violently than the last. Your entire body was in sparking, euphoric bliss. Curses, screams and moans poured from your throat, all laced with his name.

“Oh, that’s it princess, let it all out for me.”

And you did just that. He kept the stream on your bud through your high and somewhere between his grainy voice talking you through and your overstimulation, another wave of pleasure washed over you. Your throat grew sore from your incessant noises that now probably sounded like gibberish sprinkled with his name.

He slowly drew the metal shower head away from your core to carefully lull you from your high. You were nothing but a heaving, shakey, fucked out mess in his grasp.

“Good job baby.” He pressed a kiss to the side of your head. “You did so good for me.”

A lazy smile spread across your lips and nodded slightly. His warmth was the only thing tethering you to reality.

He let you recover from your orgasms before moving on. His hands found your hips once more and pressed you against him. You felt his own arousal thick and hard against your lower back and it reminded you of the ache between your legs that only he could fill.

“You wanna turn around for me baby?”

While you felt like utter mush in his hands, his offer sparked the potential of having him inside you, and that was something you didn’t plan to pass up on. You nodded and shifted around in the water, letting the liquid slosh around tub even spilling out a bit unintentionally. “Oops.” You giggled.

“Hi angel.” He says softly with a crooked smile painted across his lips the second his eyes meet yours. Sure, he held the reigns in the bedroom and most other areas of your relationship, but it was no secret that you were the one with complete control over him. You made him weak in ways he never imagined being, he would give you anything you wanted if you just batted your lashes at him. He was putty in your hands, and he loved it.

He looked so beautiful, and you suddenly felt scammed knowing that you had your back to him looking like that the whole time. His raven hair had fallen from the makeshift bun from the couch and was now splayed over his shoulders, the ends now damp and pointy. You couldn’t wait one more second without his lips on yours, so you scooped up his face in both hands and met his lips with yours. You broke the kiss to press your forehead against his, wanting to engulf yourself fully in his stormy eyes. “I love you.” You whispered.

“I love you too.” He replied matching your whisper. His hands found your hips again, pulling you towards him – not out of desire to intensify the moment, but simply to have you closer. “God, I love you more than anything.”

Peachy pink dusted your cheeks and the smile that his words brought to your lips was embarrassingly wide. You shied away from him and shook your head, “You’re being silly.” Out of all the grand things in his life, you were sure that you were the least exciting or interesting part.

His hand trailed warm water up your arm to pick up your chin, “I’d never joke about that.” His thumb grazed over your cheekbone, cupping your cheek. “I’m so grateful for the patience you’ve given me, given us. You might be the best thing to ever stumble into my life.”

Every atom in your body begged to mesh with him. It only took one exchanged look between you two for your bodies to rearrange so you could sit on his lap. Your lips collided, followed by a messy display of clashing teeth and hungry tongues. Your passion was fueled only by the blind love you had for him and your desire to prove that his love for you was warranted. Your fingers tangled into the base of his dark hair, tugging at it slightly needing every bit of him entwined with your very molecules. He kept one hand on your hip while the other held tangled in your own wet hair.

As much as you wanted to keep telling him how much you loved him, you couldn’t bear to break away from him even for a second. If you couldn’t tell him, you’d show him.

You rutted your hips up his thighs until you felt the base of his member rest against your bare cunt. He let a groan out into the kiss at the feeling of you against him. One of your hands fell from his hair to his length, your fingers instinctually molded around the silky soft flesh. It never ceased to impress you at just how big he was and no matter how many times you’d had him it never eased the ache of taking him.

His sizeable cock was decorated with bulging veins from the blood that coursed through him. Even though your fingers had grown to be expertly familiar with his anatomy, you still loved exploring him, tracing each vein with your fingertips. This earned you another grunt from somewhere deep in his chest and you pridefully smiled against the kiss.

You finally gave him what you knew he wanted, wrapping a hand around this girth and began palming him slowly. His member had a delicious upward curve to it that helped to reach the deepest and most sensitive part of you. Your mouth was watering at just the feeling of him in your hand – in that moment you could’ve sworn that you would do absolutely anything to have it inside you. It was not a want, but a carnal need.

He finally had enough and pulled from the kiss, “Baby, please.” He breathed out against your lips, his love drunk eyes heavy with lust as he looked up at you. “I need your pussy.” His chest rose and fell in time with yours, needing you just as badly as you needed him.

You nodded quickly against him before lifting yourself up enough to hover over him. Regardless of how much you wanted it, you still had to mentally prepare yourself for the initial pain. Nick helped align himself with your entrance while keeping a supportive hand on your hip bone. You exhaled a deep breath.

Sensing your hesitation, he gave your hip a small squeeze, “You can take it baby, just go nice and slow. We have all the time in the world.” He reassured you, letting you set the pace.

You nodded and carefully began to sink down on him. A hiss escaped your mouth at the way his width stretched you open. Your hand fell to his shoulder for support as you struggled to pull yourself further down.

Nicholas’ eyes couldn’t soak you up enough, he was mesmerized at the sight of you. He wished he could burn it into his brain. “God, you look so fucking pretty taking my cock.”

His compliment only made you more determined to push past the pain and discomfort. When you felt your cervix land on his tip you knew that was as far as you could take him. While you couldn’t reach his base fully, you were still surprised and proud of yourself for being able to take so much of him in that position.

He let out a low groan at the feeling of your cunt tightly enveloping his cock. “You feel so fucking good.”

You expelled a breath then swirled your hips with him still deep inside you. The goal was to adjust to his size before riding him. The stretch burned but you knew it’d sweeten once you started moving.

The way he gazed up at you made you weak and your body gave into him, falling into the crook of his neck. You began placing open mouth kisses on his tattooed throat while your hips started swiveling on him. Light, airy moans tumbled from you lips and onto his neck. His hands gripped your hips tighter, letting out a grunt from somewhere deep in his chest.

“Fuck,” He groaned, letting his head fall back into the ledge of the tub. “I need you to move baby, I need more.”

You nodded quickly, needing it just as badly. Your hands slipped off him to stabilize yourself on the porcelain ledge. It gave you enough balance to raise your hips up almost fully, before dropping them where he filled you the fullest.

“That’s it, you’re doing so good.” He groaned out, his eyes droopy and drunken by only his love for you.

The praise helped motivate you to keep going even though the stretch burned. But you got to control the pace and the depth you could handle – although part of you wished he did have control so that he would forego any hindrances and use you up fully.

You gained momentum on him, bouncing up and down on his cock. Water splashed everywhere, over the ledge and all over the floor but that was the furthest thing on your mind. The room was filled with moans, grunts and cursed from both of you. You felt the knot beginning to form in your tummy as did he. But his surprises weren’t done yet.

He reached over to where he’d placed the shower head, easily flipping it on to the previous setting. Your eyes rounded as he began to lower it towards the water and you shook your head vigorously. “No, no, no.” You cried. “I won’t last, please, no.”

His other hand drifted down your spine with a feather light touch. “Well, that’s the point sweetheart.” He hummed. “Don’t you wanna cum again for me baby?” He questioned patronizingly. You knew that tone and you knew it meant it wouldn’t be as easy as he was eluding.

He continued his actions and aimed the powerful stream of water directly at your clit. A jolt of pure electricity zipped up your spine and down your thighs. Your entire body shuddered at the sudden and intense sensation. Your fingertips curled into his skin, surely branding claw marks into his flesh. “God, fuck.” You exclaimed loudly, barely able to move.

“Now, baby, remember that cumming is a privilege remember? I could very well leave you all worked up with your pretty pussy clenching around nothing if you misbehave.” He warned. “Do you understand?”

You nodded quickly, slipping your tongue between your lips. But that of course wasn’t enough for him.

His hand tightened on your hip and brought the shower head a bit closer to heighten the sensation. “I believe I asked you a question darling.” His voice deep and raspier than normal. “Do you understand? You know I need to hear it.”

“Yes,” You shuddered out. “Yes, sir. I understand.” You couldn’t seem to catch your breath, the air in your lungs completely vacant. Your heart thumped so hard against your ribcage you thought it might shatter and burst in front of him and splinter his own chest.

“Good girl.” He praised. “Now, I don’t remember telling you that you could stop moving.”

You whined in near agony, squeezing your eyes shut and slowly beginning your movements again. “Fuck.” You lulled your head back, buzzing pleasure spreading through every bit of you.

“Faster.” He commanded. “Or I’m gonna make this very unpleasant for you.”

His sweetness was long gone and replaced by the Nick you had grown very familiar with. You’d never guess by his normal relaxed and reserved demeanor that he’d have this overwhelming dominance in bed, but you loved it. It was as though something in him would take over, like he’d try to fight it to stay sweet and romantic, but it rarely lost the fight. It was thrilling to watch his internal battle; you’d seen it so often that you had memorized the shift in his eyes and subtle change in his cadence.

You rarely chose to challenge his threats and today was no different, So, you began lifting and dropping your hips against his lap, taking in fully – or as much as you could anyway. His free hand slithered up your side to cup your breast, kneading the plump flesh in his grasp. His stare couldn’t seem to stay on any solid one part of you, darting from your tits bouncing as you moved, to your face contorting with the overwhelming pleasures you were experiencing, to down where you were connecting with him. He looked at you the way people look at monuments or ancient architecture. He didn’t care about a single other wonder in the world because he was convinced you were the only one in existence. You were an art museum to him, every single installation he could study for hours and never grow bored of your beauty and the delicate nature of your soul. He was utterly infatuated with and devoted to you.

It became difficult to continue riding him without getting sloppy from another orgasm building quickly in your stomach. Your clit was buzzing and threatening to tip you over the edge at any moment. The way he filled you up only made it worse – being full of him made the time without him even more empty. You’d never had someone fill you up so much, he made it hard to even clench around him. It was an incredible experience and one that would make having anyone else subpar. He had set the bar so high that it made it impossible for anyone else to measure up to him. If he ever decided he’d had enough of you, you’d spend the rest of your days seeking bits of him in anyone you ever let touch you. He’d certainly haunt you worse than phantom ever could.

Thankfully, from the way his cock throbbed and bounced inside you, told you that he was getting close too. Your heart thumped so hard in your throat that you questioned if you’d even be able to speak.

“I-I’m close.” You whimpered out. “Can I cum?”

He tsked at the request. “Now baby, I taught you better that. You’re forgetting my favorite word. Try again.”

Your palms dug into his chest at his rebuttal. “Fuck.” You closed your eyes attempting to stave off your orgasm. “Fuck, please.” You begged. “God, fuck, please, I need to cum. Please can I cum?”

“Hm.” He feigned a thought. “No, not yet. Hold it.”

You shook your head vigorously, “No, no, no, please I can’t. I won’t make it, I’m so close. I don’t know if I’ll be able to stop it.”

“You can and you will.” He said simply. “And if you don’t, you don’t wanna know how much you’ll regret it.”

His face was serious, but you could tell that the excitement was growing in his belly too. You swore that he thrived over your desperation, he loved seeing you squirm and bringing to the edge of your limits. It was sadistic the way he was fueled by your anguish. You don’t know if you��d ever admit it, but you enjoyed being commanded and used like a plaything. Being at his mercy was a thrill you loved chasing, especially knowing he’d always catch you.

You scrunched your eyes closed and bore down on your teeth holding on to the tattered thread left holding you on to your sanity. “Fuck.” You breathed out. It was almost painful how your sensitive nub throbbed beneath the powerful stream of water and how tight the knot in your tummy had grown. His tip assaulting your cervix intensified everything and overbearing pleasure was looming merely seconds way from shattering your resolve. “Fuck, fuck.” You whined. “Fuck, please, please let me cum, I need it so bad. Please I don’t want to disobey you but I’m so close, I need to cum, please – fuck, I can’t hold it, fuck fuck, please can I cum?” Your pathetic groveling was a pitiful display, but it was one that Nicholas could barely handle himself. He could get off from the hymns of your desperation alone.

“Fuck I love when you sound like that.” He groaned. “Fine baby, cum all over my fucking cock.” If he hadn’t been so close himself, he surely would’ve stretched out the torture.

As if you needed anymore help, he brought the shower head even closer. The heightened sensation instantly blinded you, causing your entire body shudder as sparking euphoria bloomed from your core. This orgasm was more powerful than the others due to the delayed pleasure and his length hitting your sensitive spot directly. The moans and curses that left your mouth were vulgar and smeared with the unholy devotion you had for him. Every cell in your body belonged to him just as he demanded it.

Your walls tightly clenching around him was his tipping point. “God, you look so fucking good with my cock so deep inside you.” He growled, gripping your hip hard enough to leave bruises behind. “Fuck baby you’re gonna make me cum.”

You were too lost in your own bliss to really hear what he said until you felt his length twitch inside you followed by his warm seed filling your core. If you weren’t so overspent, the feeling alone could’ve sent you into another orgasm – but seeing as you were still working through your own, you weren’t that concerned about it.

As you both came floating down from your highs, he flipped off the shower head and set it to the side ledge. You had fallen on his chest while your heaving chests rose and fell in time with each other’s. His fingertips raked through the slightly damp hair of your scalp. You purred and smiled at the affection gesture.

He grinned at the reaction, “I love you.” His buttery words fell from his lips in a tone just above a whisper.

Nick would never admit it, but he was extremely talented at almost anything he ever picked up. If he gave it a good honest try, it wouldn’t take long for it to become second nature. He never imagined that there would be anything in the world that would come easier than a graphite pencil or tattoo gun or almost any instrument he picked up. He knew his tattoo gun and his favorite guitar like the back of his hand and while he’d never fully believe it, he already knew you that way too. As with everything else, just because he was a master-of-all didn’t mean there were never any bumps or challenges or hardships – pencils snap, tattoo guns malfunction, and sometimes strings don’t want to tune just how you want them - above all else, Nicholas knew that the most. He knew the best things in life were never easy, but that never stopped him before and it certainly wasn’t going to stop him now.

“I love you too.” You muttered sleepily into the crook of his neck.

The satisfaction of inking a particularly difficult design or mastering a challenging new riff could never compare to the feeling he got from hearing you say those words.

“C’mon, let’s get you dry and warm.” He gently patted your hip and you nodded, using every bit of strength in your body to sit yourself upright.

Nicholas was incredible in his element. It’s one thing to be able to take control sexually, but it’s a whole other thing to be able take gentle control outside of that – and he did, effortlessly. He carefully pulled you off him and got you standing on your feet. He only allowed the air conditioning to dance on your skin for a millisecond before he wrapped a big fluffy towel around you. You tugged the terrycloth fabric so tight against your skin that you were sure you’d have imprints of the threads embedding into your skin. When you lifted your leg over the porcelain, you felt the familiar ache between your thighs that always came from loving him. It wasn’t the worst you’d felt, since you had set the pace, but the water supplied no lubrication, and you were definitely feeling the repercussions.

Nick wrapped a towel around his waist and unplugged the bath drain. When he finally made his way back over to you. When you were both barefoot it really emphasized just how much he actually towered over you. The water droplets glistening across his tan, inked skin made him look like a work of art. Your eyes traced his collarbones and landed on the thorny pendent you were fidgeting with before.

“Oh yeah, before I forget.” You didn’t realize what he was doing until he pulled the necklace from neck and gently draped it over your head. It landed way longer on your chest but it didn’t matter. Your fingers found the pendent and immediately rubbed it for comfort.

“I can’t take this.” You claimed, but the smile that had already made home on your face said otherwise.

He smiled and took your jaw into one hand and placed his other hand over yours covering the necklace. “I’ll always be with you now. If you miss me or get anxious just squeeze it, and I’ll be right there with you. Okay?”

Tears burned your eyes, but you were determined to keep it together, the last thing you wanted to do was cry in front of him naked and shivering. You nodded quickly, “Thank you.” You whispered, hiding a sniffle.

“You’re welcome baby.” He said and placed a quick kiss to your forehead.

He gently grasped your shoulders giving them a little rub to warm you up before guiding you back into the bedroom. The edges of his lips dipped into a frown the second he noticed your limping.

“Oh baby, did I hurt you? I knew we should’ve gotten out of the bath-” He always began to panic ramble if he thought he might’ve hurt you or not taken care of you properly.

You giggled at his worrisome nature and placed a finger over his lips. “It’s okay, really.” You reassured and watched his anxiety disappear. “But it does hurt.” Your lips pulled together in a pout. “Fix it?”

A small smile pulled across his lips and he nodded knowing exactly what that meant.

The time after with Nicholas somehow always felt more intimate. He was driven to love you the best way he knew how, and you relished in the safety he wrapped you in. No matter how rough he got in bed, afterwards he always handled you like a freshly plucked gardenia. He was convinced that if he even grabbed you the wrong way you’d crumble. But he loved it, he was sure that if he was put on this earth to do one thing, it was to take care of you.

After applying some numbing cream where you ached the most and getting you into some fresh pajamas, you were finally exactly where you wanted to be. You were tucked right into Nick’s side, cozy under the covers, sharing a pint of pistachio ice cream while watching reruns of your favorite mutual comfort show.

You looked up at him when he laughed at something silly in the show and the glow from the tv illuminated his features beautifully through the darkness. In that moment, he gave you every bit of reassurance you needed to handle him being gone. You were his and he was yours, and as long as you loved him, he’s always come home to you if you let him.

He glanced down at you, catching you in your admiring stare. The edges of his lips pulled taut into a wide, toothy smile.

“Bob’s Burgers is over there you know.” He teased, tilting his head across the room.

You giggled and burrowed your face into his chest. “You’re much more entertaining.”

He chuckled in disbelief, “Am I?”

“Mhm.” You hummed, getting sleepy the second your head touched his chest.

He laughed softly and precariously plucking the empty pint of pistachio from your dozing grasp to put on the bedside table. He pulled you closer to him and tugged the fluffy duvet higher to cover you both.

Before you let sleep envelope you, you felt his fingers tenderly massaging your scalp. “I love you.” He whispered.

“I love you too, Nicholas.” You hummed back lovingly, nuzzling into his chest.

Taglist; @neverknoah @lma1986 @baddestomens @deathblacksmoke @philomenie @blacksoul-27 @thcfountain

A/N; Thank you so much for reading, i hope you liked it, lmk if you did<3

[randomquadballpun]

DAY 5 (attempt no 2)

"Bacteria please, Watson!"

Sherlock and Rosie were back in laboratory mode, goggles, gloves and coats donned, while John sat at his desk with a cup of tea and scrolled through the latest comments on his blog.

Over at the kitchen table, Sherlock held open one of the growth medium-filled Petri dishes and offered it to Rosie. With a tense expression that spoke of utmost concentration, Rosie dispensed a few droplets of bacteria solution in the middle of the plate with a pipette that looked like Sherlock had lifted it straight from one of the Barts laboratories. Knowing Sherlock that possibility was not even very unlikely.

Sherlock placed the dish down gently in front of himself on the table.

"Glass pipet please, Watson!"

He extended his empty hand and Rosie placed a disposable glass pipet in there, just as demanded.

With practised movements, Sherlock held the glass tube by one end and stuck the thinner side into the hottest part of the flame until it glowed red hot and began to droop under its own weight. Once it was bent at a 90° angle he repeated the process with the very tip of the thin glass before holding it away from the flame with a flourish until it stopped glowing.

"Next you can cool it down to bacteria-safe temperatures by pressing it gently against the growth medium, but be careful to avoid the actual bacteria until you are sure it is all cooled down!", he narrated as he lowered the bend pipet tip to the petri dish were it indeed cooled down with a quiet sizzle. "And then you can spread the E.coli with gentle, circular movements, just don't press down too hard or you are going to slice up the agar." He demonstrated the procedure with his customary level of grace and finished by closing up the plate, turning it upside down and handing it off to Rosie.

"Into the incubator please, Watson." She carried it off reverently as if she had been handed a great treasure and not just a small plastic plate containing some glorified gut bacteria.

While Sherlock started cleaning up the workspace, his eyes wandered over to John for the first time in a while. His light gaze immediately spotted the cup in his hands.

"Tea, John?"

John crossed his arms in mock protest. "What? I don't get watsoned around?"

Sherlock stared at him in genuine bafflement while peeling off his gloves and chucking them into the bin underneath the sink. "No, why? Watson is Watson, you are my John!" He gave Rosie an exaggerated wink overtop Johns head before returning to the topic at hand. "Tea please, John?"

At least he had the decency to make it sound more like a request than a demand. But John had come prepared. He picked up one of the two extra cups that he had brewed before and pressed it into the other mans waiting hand as soon as he was done cleaning up at the sink.

"Here you go, my Holmes!"

--------------------

Troubleshooting, part 4/?

-> I have started uploading the first finished chapter on ao3 as well (so attempt no 1), so if you prefer to read it over there, just click here!

-> The next snippet can be found here!

-> Start reading right at DAY 0 or read the previous part here.

[theineated]

Okay so I'm watching Sweet Tooth and I'm beginning to think people should hire science consultants.

Who thought making a pandemic-based show without paying attention to basic lab techniques was a good idea??

You don't put the white part of a pipette into the liquid. You're contaminating the liquid. You shouldn't even submerge the whole disposable tip!! For a more accurate measurement you should submerge it just enough for it to suction properly.

DO NOT PUT FULL PIPETTES UPSIDE DOWN. He just ruined a good pipette. All the liquid went into its inner mechanisms and it won't work properly now.

They aren't the only offences but they're the most visually jarring ones (for now).

Those are basic lab techniques. Someone in 1st year of lab-oriented studies would know that. I would expect a series with science as one of its core plot points to know it as well

[microlitseo]

Training Lab Personnel on the Proper Use of Liquid Handling Instruments

Liquid handling instruments, such as pipettes, dispensers, and burettes, are essential tools in laboratories across various scientific disciplines. Proper use of these instruments is crucial for accurate and reliable experimental results. Training lab personnel on the proper handling techniques ensures consistent performance, prevents errors, and protects valuable samples. 

Importance of Proper Technique

Accuracy and Precision: Correct use of liquid handling instruments guarantees accurate and precise transfer of liquids, preventing experimental errors and ensuring data reliability.

Sample Integrity: Proper handling techniques minimize contamination risks, preserving the integrity of valuable samples.

Instrument Longevity: Correct use extends the lifespan of liquid handling instruments, reducing the need for frequent repairs or replacements.

Safety: Proper techniques help prevent accidents and injuries, ensuring a safe working environment for laboratory personnel. 

Key Training Areas

Instrument Selection:

Match instrument type (micropipettes, micropipettes, dispensers) to the volume range and liquid properties.

Consider factors like accuracy, precision, and ease of use.

Calibration and Maintenance:

Regular pipette calibration ensures accurate dispensing.

Teach proper cleaning and maintenance procedures to prevent contamination and prolong instrument life.

Pipetting Techniques:

Demonstrate correct pipetting techniques, including:

Plunger pressure and speed

Tip immersion depth

Avoiding air bubbles

Proper tip disposal

Emphasize the importance of using appropriate pipette tips for different liquid types.

Dispenser Usage:

Explain the proper operation of dispensers, including:

Setting the desired volume

Filling the reservoir

Dispensing the liquid

Cleaning and maintenance

Address specific considerations for different dispenser types (e.g., serial dispensers, repetitive pipettes).

Burette Handling:

Demonstrate the correct use of E-Burette for titration and other applications.

Teach proper filling, reading, and draining techniques.

Emphasize the importance of avoiding parallax errors when reading the meniscus.

Troubleshooting and Error Correction:

Provide guidance on common issues, such as leaks, air bubbles, and inaccurate dispensing.

Teach troubleshooting techniques to identify and resolve problems effectively. 

Training Methods

Hands-on Practice: Encourage trainees to practice using liquid handling instruments under supervision.

Demonstrations: Provide clear demonstrations of proper techniques.

Role-Playing: Simulate laboratory scenarios to reinforce learning.

Quizzes and Assessments: Evaluate trainees' understanding and competency.

Online Resources: Offer access to online tutorials and resources for additional learning.

By providing comprehensive training on the proper use of liquid handling instruments, laboratories can ensure accurate, reliable, and safe experimental procedures. Investing in training not only improves data quality but also contributes to a positive and productive laboratory environment.

[accumax]

Micropipette Guide 2024: Types, Applications and More

Micropipettes or pipettes, are instruments used to measure liquid ranging between volumes of 1-10000 µl and transfer it from one sample container to another. This is a basic liquid-handling instrument for almost all scientific laboratories.

Types of Micropipettes

There is no 1 way to classify micropipettes. It can vary in a number of ways.

1. Number of Channels

Single Channel Micropipettes

A single-channel micropipette has only 1 channel to aspirate and dispense the liquid. It means you can handle only one sample at a time.

Multi-Channel Micropipettes

Multi-channel micropipettes can handle 8, 12 or 16 samples in one go. It can attach multiple tips at the same time and you can get the work done faster especially if working in high-throughput labs.

2. Volume Adjustment

Fixed Volume Micropipettes Here the volume a pipette can aspirate and dispense remains the same and you don’t have the option to adjust or choose between a range. They offer consistent and accurate results for repetitive pipetting.

Variable Volume Micropipettes

Variable volume pipettes give you the flexibility to choose the volume you want to pipette (within the given range). You need to set the volume manually on the dial. High-performance pipettes also come with a volume lock feature for enhanced safety and reliability.

3. Operating Mechanism

Mechanical Pipettes

These are the standard pipettes widely used in all laboratories. Mechanical micropipettes operate on a piston-driven system, where users manually set the desired volume using a dial and apply thumb pressure on the plunger to aspirate and dispense liquids.

Electronic Micropipettes

Electronic micropipettes are more expensive than mechanical ones because they have digital controls, programmability and eliminates the element of human error to a certain extent. It has an electronic display and is ideal for high-throughput labs where reproducibility is paramount.

Components of Micropipette

Plunger

The plunger is one of the main components of the micropipette. Use your thumb to press down on the plunger to aspirate and dispense the liquid.

Then, with a firmer push, sometimes called the “blow-out stop,” it ensures a thorough expulsion of any remaining liquid, guaranteeing accurate measurements—a two-step process of liquid control.

Ergonomics are a key point here since lab professionals will be pipetting repeatedly for long hours. A low-force mechanism which does not require excessive plunge force, will minimize the RSI.

Volume Adjustment Dial

By twisting the volume adjustment dial, you dictate the micropipette’s plunger movement, determining your experiment’s liquid dosage. In micropipettes with adjustable volumes, this feature offers precise measurement control, no matter how small or large the quantity is.

Tip Ejector

Keep your hands and micropipette clean by disposing of used tips promptly. Utilize the convenient tip ejector button to effortlessly remove micropipette tips, ensuring a fuss-free and contamination-free experiment environment.

Tip Cone The tip cone, also known as the shaft, is the crucial component of a micropipette where the disposable tip is inserted. Its primary function is to ensure a snug fit for the tip, ensuring precision in measurements and preventing air leakage. Its adaptable shape accommodates various sizes and styles of tips, allowing for versatile and secure usage without concerns of detachment or disruptions.

Calibration Screw Inside the micropipette lies a crucial component, the calibration screw. This is what makes accuracy possible. Twisting this tiny screw adjusts the liquid output, fine-tuning the micropipette’s performance. Regular checks and tweaks, as advised by the manufacturer, ensure precision in your measurements, keeping everything flowing smoothly.

Applications of Micropipettes in Laboratory

Micropipettes are used to measure any small amount of liquid samples for testing and research. They are crucial in lab settings like molecular biology and diagnostics, precisely transferring tiny liquid volumes, facilitating diverse experiments. Mastery of their principles is key to effective scientific research and analysis.

Some common applications include:

1. Molecular Biology 2. Biochemistry 3. Cell Culture 4. Microbiology 5. Analytical Chemistry 6. Clinical Diagnostics 7. Pharmaceutical Research

How does a Micropipette work?

Micropipettes operate on the principle of air displacement. They consist of a plunger connected to an internal piston, which moves to two distinct positions: Filling Position: When the plunger is depressed to the first stop, the internal piston displaces a volume of air equal to the desired volume shown on the volume indicator dial. This creates a vacuum, drawing the liquid into the tip. Dispensing Position: The second stop on the plunger is used solely for dispensing the contents of the tip without drawing in additional air.

How to use a micropipette?

1. Start with choosing the right micropipette and micropipette tips

Select the one that is best for your application. While pipettes are similar in the way they function, what sets them apart is the accuracy and precision of the measurement, ergonomics and general durability of the instrument.

Set the volume based on your requirement and ensure the tips match the volume of the pipettes.

2. Attach the micropipette tip to the micropipette

Don’t use excessive force here because good quality pipettes will be quick and seamless to attach to the tips and should provide a leak-proof seal.Immerse the pipette in the liquid at 90 degrees Be mindful of your posture and keep the position upright. Aspirate and dispense 2-3 times before actually measuring the liquid

3. Forward or Reverse Pipetting

First let’s talk about forward pipetting:To aspirate the liquid in the tip, press the plunger to the first stop. Immerse the pipette tip vertically in the liquid. Slowly release the plunger while the tip is immersed. The liquid will be aspirated into the pipette tip. To dispense the liquid, place the tip on the inner wall of the receiving vessel at a steep angle Slowly press the plunger to the first stop to dispense the liquid. To empty the tip completely, press the plunger to the second stop.

Now for reverse pipetting

The reverse technique is suitable for dispensing reagents/solutions that have high viscosity or a tendency to foam easily. It is also recommended for dispensing very small volumes.To aspirate the liquid in the tip, press the plunger to the second stop and immerse the pipette tip vertically in the liquid. Slowly release the plunger while the tip is immersed. The liquid will be aspirated into the pipette tip. To dispense the liquid, place the tip on the inner wall of the tube at a steep angle. Slowly press the plunger to the first stop. Finally, eject the tip and dispose it off

Calibration of Micropipettes

Calibration is conducted through gravimetric testing, which involves weighing the amount of pure water delivered in a single operation of the pipette. The obtained mass is divided by the density of water to determine its volume. Variable volume pipettes should undergo testing at three or more points across their designated range, typically at maximum volume, 50% of maximum volume, and the lower limit of their range.

Here’s a general guide on how to calibrate a micropipette:

1. Gather MaterialsMicropipette(s) to be calibrated Appropriate pipette tips Distilled water or a calibration solution Weighing balance with appropriate accuracy (usually in milligrams) Gloves and lab coat for safety

2. Prepare the Micropipette Ensure the micropipette is clean and free from any residue. Attach a fresh and compatible pipette tip to the micropipette.

3. Pre-Wet the Pipette Tip (Optional) For some micropipettes, pre-wetting the tip with the liquid being used can help ensure accuracy. Follow the manufacturer’s recommendations regarding pre-wetting.

4. Prepare the Calibration Solution Use distilled water or a calibration solution recommended by the micropipette manufacturer.

Ensure the calibration solution is at room temperature to minimize density variations.

5. Set the Micropipette to the Desired Volume Adjust the micropipette to the volume you want to calibrate (e.g., if calibrating a 10-100 μL micropipette, set it to 50 μL).

6. Dispense Liquid into a Weighing Boat or Container Dispense the liquid from the micropipette into a weighing boat or a container placed on a weighing balance.

Note down the initial weight (W1) of the liquid dispensed.

7. Weigh the Dispensed Liquid Carefully weigh the liquid dispensed using the weighing balance. Ensure the balance is calibrated and accurate.

Record the final weight (W2) of the liquid.

8. Calculate the Dispensed Volume Subtract the initial weight (W1) from the final weight (W2) to determine the weight of the liquid dispensed (W).

Convert the weight of the liquid dispensed to volume using the density of the liquid or the known density of the calibration solution.

Calculate the actual volume dispensed using the formula:

9. Compare with Expected Volume Compare the calculated volume dispensed with the expected volume (e.g., 50 μL for a 10-100 μL micropipette). Calculate the percent error to assess the accuracy of the micropipette calibration:

10. Adjust if Necessary If the percent error is within an acceptable range (typically ±2-5%), the micropipette is calibrated. Otherwise, adjustments may be needed. Consult the micropipette’s user manual for instructions on how to adjust the volume settings. Adjust carefully and recheck the calibration until the desired accuracy is achieved.

11. Record Calibration Data Keep a record of the calibration process, including the micropipette serial number, date of calibration, volume settings, calibration solution used, measured weights, calculated volumes, and any adjustments made.

12. Final Checks After calibration, perform a final check to ensure the micropipette is dispensing accurately and consistently across the volume range.

When is micropipette calibration required?

Micropipette calibration is typically required in the following situations:

Initial Use

New micropipettes should be calibrated before their initial use to ensure accuracy and precision.

Scheduled Calibration

Regular calibration intervals are recommended to maintain the accuracy of micropipettes over time. The frequency of calibration depends on factors such as the frequency of use, the criticality of the measurements, and the manufacturer’s recommendations.

After Maintenance or Repair

Calibration should be performed after any maintenance or repair work on the micropipette to verify that it meets the required specifications.

Change in Operating Conditions

If there is a significant change in the operating conditions, such as temperature or altitude, recalibration may be necessary to account for these factors’ effects on the micropipette’s performance.

Compliance Requirements

Laboratories may have regulatory or quality assurance requirements that mandate regular calibration of micropipettes to ensure traceability and compliance with standards.

Where do we get the best micropipette for the lab?

When purchasing a micropipette for your lab, consider key factors such as accuracy, precision, ergonomics, and ease of maintenance. Research the brands and models, compare specifications, and read user reviews to make an informed decision. Evaluate additional features like adjustable volume settings and compatibility with automation systems. Set a budget and balance costs with desired features. Check warranty coverage and customer support options for added peace of mind.

Cleaning and Maintenance of Micropipettes

1. External CleaningRemove and Clean the Tip Ejector: Begin by detaching the tip ejector and giving it a thorough wipe-down.

Wipe Down All Exposed Surfaces: Take a lint-free cloth or tissue and carefully wipe all visible parts of the micropipette, including the body, buttons, operating rod, and tip holder. Be diligent in cleaning any scuffs, marks, or accumulated debris in hard-to-reach areas.

Use a Brush for Stubborn Debris: If there are persistent stains or dirt, consider using a soft-bristled brush to gently scrub the affected areas.

Reassemble and Allow to Dry: Once the exterior surfaces are clean, reattach the tip ejector and ensure it is securely in place. Leave the pipette to air dry completely before further use. Final Wipe with Cleaning Solution: Finish the cleaning process by wiping down the outer surfaces once more with a cleaning solution to remove any remaining residue. Allow the alcohol to evaporate fully before returning the pipette to service.

2. Internal Cleaning

Cleaning the inside of a pipette should be handled by trained personnel to avoid incorrect reassembly, which can damage the micropipette and affect its performance, leading to decreased accuracy and potential leakage.Disassemble the Micropipette: Carefully take apart the pipette, placing the upper part in a clean, dry area.

Wipe with Alcohol-Coated Wipes: Use alcohol-coated wipes to thoroughly clean the entire interior, including the body, connecting nut, tip holder, O-ring, seal, and the stainless steel surface of the piston. Ensure the piston is completely dry to prevent corrosion.

Allow Alcohol to Evaporate: Let the alcohol evaporate fully from the interior of the pipette. Check for Lubrication Needs: Refer to the instruction manual to determine if any parts, like the piston assembly and seals, require lubrication. Follow the manual’s guidance for reassembly, ensuring proper alignment and placement of components.

Maintaining Micropipettes

When the pipette is not in use it should be stored in an upright position. The pipette should be inspected prior to use each day for any dust or contamination on outside surfaces. Special attention should be given to the tip cone. No solvent other than isopropanol should be used to clean the pipette. If the pipette is used daily, an internal parts inspection should be performed every three months.

Choosing the right micropipette for your applicationEnsure that the micropipette can accommodate the desired range of liquid volumes for your pipetting needs.

Verify if the micropipette features a universal tip cone to accommodate various types of pipette tips.

Check if the micropipette is autoclavable at the necessary temperature to ensure proper sterilization.

Check if the micropipette is UV resistant so that they can be kept inside the hood even when the UV mode is on.

Assess the ergonomic design of the micropipette for smooth and comfortable handling during use. Confirm if the micropipette is calibrated to guarantee precise dispensing of liquids.

Evaluate the accuracy and precision of the micropipette’s readings to ensure compliance with ISO standards.

Ergonomics is a key factor in choosing a pipette because repetitive strain injury is common amongst lab personnel who pipette regularly. Low-force tip ejection and minimal plunge force are crucial.

Accumax Lab Devices specializes in manufacturing high-precision liquid handling instruments for top-tier laboratories worldwide. With a focus on innovation, it offers an advanced range of micropipettes designed to enhance user experience within real-world laboratory settings. Especially our range of FAB and FAB LF pipettes, which are specially designed for accuracy and precision with excellent ergonomics to elevate your pipetting experience like never before.

Micropipette FAQs

1. Can I use any brand of pipette tips with my micropipette?

Whether you can use any brand of pipette tips with your micropipette depends on its tip cone design. If your micropipette has a universal tip cone, it means it’s compatible with a wide range of international pipette tip brands, as long as they’re suitable for your micropipette’s volume capacity.

2. What’s the best way to sterilize my pipette before use?

To clean your micropipette before using it, first, check if it can be sterilized using an autoclave. If it can, follow the instructions in the manual to know the right temperature and duration for sterilization. Make sure to consider the type of liquid you’ll be using it for.

3. Is there a simple way to check if my micropipette is calibrated correctly?

Set it to the usual volume, then dispense water five times. Weigh what you piped out on a scale. If it matches up nicely with the ISO standard, your micropipette is good to go. If not, it’s time for a recalibration.

4. How frequently should I recalibrate my micropipette?

For regular use, it’s good to check your micropipette’s calibration every 3 to 6 months. Following the ISO 8655 standard, it’s recommended to have it calibrated annually.

5. How to adjust the volume of a micropipette?

To adjust the volume on your micropipette, look for the display showing numbers indicating the volume range. If you have a fixed-volume micropipette, the range is predetermined. However, if you have a variable volume micropipette, you can adjust it within the given range by using the rotational dial located at the top of the micropipette plunger. Alternatively, you can consult the manual for specific instructions on changing the volume.

6. Why is it important to avoid touching the tips of the micropipette?

When you touch the tips of a micropipette, you risk transferring oils and other substances from your fingers onto them. This can interfere with the accuracy of volume measurements and potentially contaminate your samples. To maintain precision and avoid contamination, it’s best to handle the micropipette tips only with the instrument itself.

7. What happens if I release the plunger of the micropipette too quickly?

Releasing the micropipette plunger too quickly can lead to inadequate liquid draw up and dispensing, causing potential inaccuracies in your measurements.

8. What should I do if my micropipette isn’t working right?

If your micropipette isn’t working properly, it’s time for some troubleshooting. Start by double-checking if it’s properly calibrated and if the volume setting is correct. Ensure that the pipette tips are securely attached and not damaged. If the issue persists, you might need to clean or maintain the micropipette according to the manufacturer’s instructions. If all else fails, it might be time to consult with a colleague or contact technical support for further assistance.

9. Can my micropipette handle different types of liquids?

Your micropipette is designed to handle a variety of liquids, whether they’re watery solutions, viscous substances, or even oils. As long as you’re using the appropriate tip size and technique, your micropipette can smoothly pipette different types of liquids.

This blog originally posted here: Micropipette Guide 2024: Types, Applications and More

[thebusinessmagnate]

Joerg Dreisewerd: Pioneering Operations and Expansions of World-Class Medical Equipment and Consumables at SARSTEDT in Brazil

The Business Magnate. Joerg Dreisewerd, Managing Director (Brazil) and Regional Manager (Latin America), SARSTEDT. A German-based medical equipment and consumables manufacturer and distributor, SARSTEDT manufactures cutting-edge and world-class equipment and consumables for the Medical or MedTech industries. Such manufacturing industries in the medical sector design different medical equipment and a diverse range of products for hospitals, research institutes, academic institutions, industrial facilities, and surgical environments. The manufactured products and equipment are used to diagnose, monitor, and treat diseases and other medical conditions. In this article, we will be shedding light on SARSTEDT’s first South American branch located in Brazil, and how its current Managing Director – Joerg Dreisewerd, initiated and is leading operations and expansions in Latin America. Through Joerg’s impactful strategies and implementations in achieving company goals and visions as well as pioneering operations in medical supplies in Brazil, the Managing Director has successfully positioned the firm as a global manufacturer and healthcare solutions supplier. 

SARSTEDT – Company Overview:

SARSTEDT Group – the medical equipment and consumables manufacturer and distributor, is a German-based company with its head office established in Nümbrecht, North Rhine-Westphalia, Germany. The company was founded in 1961 by Walter Sarstedt who laid the foundation for this now renowned and globally recognized family business. SARSTEDT Group has over 15 production sites all across the globe in Europe, North America, South America, and Australia. The company opened its first Latin American branch in 1998 in Sao Paulo, Brazil, South America, and this expansion to Brazil was yet another successful milestone completed by the company in that year following Europe in 1971, the US in 1973, and Australia in 1991. The SARSTEDT Group, a healthcare industry leader in Brazil commenced its sales operations in what is now the world’s largest health market in in the Latin American country. 

SARSTEDT Products Manufactured and Distributed: 

The worldwide partner in Medicine and Science – SARSTEDT innovates the type of medical and laboratory products and other equipment, establishing a goal to move people forward. The company is one of the leading suppliers in the industry and develops, produces, and sells equipment and consumables to markets all around the globe. The various equipment and consumables manufactured are all state-of-the-art, technology-integrated, safe, high-quality, and high-performance products. SARSTEDT’s medical equipment in Brazil are categorized from Diagnostics (pre-analytical processes), Laboratory (solutions for molecular biology, biochemistry, cell biology, and more), and Clinic and Transfusion (clinical care), to Laboratory Automation (pre&post-analytical processes in clinical and microbiology areas). The various products developed and designed in each category will be mentioned below. 

Diagnostics – products for clinics, doctor’s offices, medical laboratories, and blood banks. Multi-safe Disposal Boxes and Erythrocyte Sedimentation Rate Devices. Collecting, sampling, and storing material samples like saliva, blood, stool, and urine are also available in Sample Collection Systems/Products.

Laboratory – for applications in molecular biology, biochemistry, and cell biology. Following certified SARSTEDT quality standards like PCR Performance Tested, Biosphere ® plus, TC-Tested, and Cryo Performance Tested, the products manufactured and designed for clean room conditions and automated production processes are Reagent and Centrifuge Tubes, The Multiply ® PCR, Molecular Biology, Micro Screw Tubes and Reaction Vessels, Liquid Handling (transfer pipettes, serological pipettes, and pipette tips), Cell and Tissue Culture Products, General Laboratory Items, DNA-free Forensic Swabs, Stands, Storage Boxes, Air Samplers, Table Centrifuges with Swing-Out Motor, Mixing Systems/Devices. 

Clinic and Transfusion – for clinical care and transfusion product segments, the products designed in this category are Urine Drainage Measuring Systems/Products, Hygiene Utensils, Warming Devices of the SAHARA product group, Sterile Closing and Stripping Devices of Blood Bag Tubes. 

Laboratory Automation – for pre and post-analytical processes in clinical and microbiological laboratories in Sample Feeding, Sample Identification, Decapping of Samples, Aliquoting, Recapping, Sorting, Distributing, and Archiving. The products manufactured and designed are Tube Labelers, Tempus600 Sample Transport System, Compact Sorters, Modular Pre and Post-Analytical Systems/Products, and the S4DX System.

Joerg Dreisewerd – The Man Pioneering and Leading Brazil’s Operations:

Joerg Dreisewerd is the Managing Director at SARSTEDT Group’s Brazil operation branch and also Latin America’s Regional Manager. Joerg has a Bachelor’s in Business Administration from the University of Applied Scinces for Business (FHDW) and was awarded best student in class during his MBA in Business Management from FGV – Fundação Getulio Vargas. The Managing Director started his career as Project Manager and later took on his current role at SARSTEDT Group Brazil in 2017. Joerg has worked in the healthcare industry for 15 years, and at SARSTEDT Group in Latin America oversaw a range of diverse responsibilities from company restructuring, turnarounds, and strategizing and implementing ESG actions in all three large, medium, and small businesses in the region. 

Initiating and leading SARSTEDT Group’s operations in Brazil, Joerg helped expand the the company’s position as a globally recognized manufacturer and distributor of hospital and laboratory equipment and consumables. By offering value-added products for customers, partners, and stakeholders of the management, Joerg envisions improving healthcare services and products regarding safety and quality. 

Joerg Dreisewerd’s Accolades from HarvardX:

Certification in “Improving Global health: Focusing on Quality and Safety”.

Certification in “LEAD1x: Exercising Leadership: Foundational Principles”. 

SARSTEDT Group’s Achievements Under Joerg Dreisewerd’s Leadership:

Joerg helped facilitate an organizational and cultural transformational transition of the Brazil branch from a centralized management to a modern governance structure. This led the company to be awarded the “Selo Paulista de Diversidade” in 2022 “Great Place to Work” in 2023 and 2024. 

The Managing Director helped the company position itself as medical solutions supplier withing the country’s main healthcare groups and for this SARSTEDT was awarded the “Top 3 Laboratory Supplier Hospital Albert Einstein Group” in 2019, 2020, 2021, and 2023. 

The “Best Laboratory Supplier of Grupo Fleury” was also awarded from 2021 – 2023.

Awarded the “Premio ECO 2023” by the Amcham São Paulo – American chamber of commerce, for Joerg’s implementation of ESG strategies and actions that established SARSTEDT as a pioneer in a Circular economy Project for pre-analytical healthcare consumables called – Caixa Magica (Magic Box).

Visit More : https://thebusinessmagnate.com/joerg-dreisewerd-pioneering-operations-and-expansions-of-world-class-medical-equipment-and-consumables-at-sarstedt-in-brazil/

[tradesworthgroup]

Latest Laboratory Equipments Solutions | Sustainable Lab Practice

Today we will discuss about Latest Laboratory Equipments Solutions. In the fast-paced world of scientific research, advancements in laboratory equipment are pivotal to accelerating discoveries and improving outcomes. From automation to sustainability, today’s Latest Laboratory Equipment’s Solutions are more sophisticated, efficient, and eco-friendly than ever. This article explores the top trends reshaping the laboratory landscape in 2024.

Automation and Robotics: The Lab of the Future

Gone are the days of manually pipetting samples or tediously documenting results. Latest Laboratory Equipment’s Solutions Automation is transforming laboratories, leading to more efficient workflows and reproducible results. Robots are increasingly common in handling repetitive tasks such as sample preparation, pipetting, and even complex assays.

Key Developments:

Automated Liquid Handlers: These systems can manage multiple tasks like pipetting, mixing, and diluting with high precision, significantly reducing human error.

Robotic Arms: Used in sample processing, these arms can handle delicate materials, reducing contamination risks.

Lab Management Software: Integrates with automated equipment to provide real-time monitoring and data analysis.

Impact: Automation accelerates research timelines, reduces labor costs, and enhances data reliability, enabling scientists to focus on more complex and creative aspects of their work.

Sustainability: Greening the Lab

Sustainability is now a priority in laboratory management. Latest Laboratory Equipments Solutions with increasing awareness of environmental impacts, labs are adopting greener practices and equipment that minimize resource consumption and waste.

Innovative Solutions:

Energy-Efficient Freezers: Modern freezers consume significantly less energy, cutting down operational costs and carbon footprints.

Eco-Friendly Consumables: Use of biodegradable or recyclable materials for labware like pipette tips and petri dishes.

Green Chemistry: Development of reagents and processes that reduce hazardous waste and environmental impact.

Impact: Sustainable lab practices not only contribute to environmental conservation but also offer long-term cost savings through reduced energy and waste disposal costs.

Miniaturization and Portability: Lab on the Go

The trend towards miniaturized and portable equipment is revolutionizing field research and point-of-care diagnostics. Compact and handheld devices now offer capabilities that once required large, stationary instruments.

Leading Innovations:

Portable DNA Sequencers: Compact devices capable of sequencing DNA on the spot, facilitating rapid genetic analysis in the field.

Handheld Spectrometers: Allow for quick chemical analysis and identification of substances outside the traditional lab environment.

Mobile Lab Platforms: Integrated systems that fit into a van or suitcase, providing full lab functionality on the go.

Impact: These advancements enhance the ability to conduct high-quality research in remote or resource-limited settings, expanding the reach and application of scientific inquiry Latest Laboratory Equipments Solutions.

Digital Integration: Smart Labs

The integration of digital technologies is creating “smart labs” where data is seamlessly collected, analyzed, and managed. Internet of Things (IoT) devices, cloud computing, and artificial intelligence (AI) are central to this transformation.

Smart Technologies:

IoT-Enabled Equipment: Connects lab instruments to the internet, allowing for remote monitoring, control, and data collection.

AI and Machine Learning: Used for predictive maintenance, optimizing workflows, and analyzing large datasets to uncover insights.

Digital Lab Notebooks: Replace traditional paper records, providing a secure, searchable, and shareable way to document experiments.

Impact: Digital integration enhances lab efficiency, ensures data integrity, and facilitates collaboration across global research teams, driving innovation and discovery.

More Here: https://tradesworthgroup.com/latest-laboratory-equipments-solutions/

[labequipmentindia1]

Clinical Laboratory Lab Equipment Manufacturers, Suppliers and Exporters in India

The clinical laboratory is vital to a hospital's ability to treat patients. Bodily fluids from patients are analyzed for their chemical makeup and evidence of disease. The high level of complex equipment does require some hospitals to obtain service contracts for the support of clinical lab equipment manufacturers in India.

A Complete Clinical Laboratory Lab Equipment List and Their Uses

Disposable Lancet:

Reliable Disposable Lancets for Accurate Blood Sampling

Convenient and Safe Disposable Lancets for Medical Procedures

High-Quality Disposable Lancets for Diabetic Testing

Pipette Tip:

Precision Pipette Tip for Laboratory Accuracy

Durable Pipette Tips for Reliable Liquid Handling

Premium-quality Quality tips for Scientific Research

Packing Envelope:

Secure Packing Envelope for Safe Shipping

Strong and Tear-Resistant Packing Envelopes for Mailing

Quality Packing Envelopes for Shipping Documents and Items

Storage Box:

Versatile Storage Box for Organized Spaces

Durable Storage Boxes for Safekeeping Values

Space-Saving Storage Boxes for Home and Office Use

Transfer Pipette:

Precise Transfer Pipette for Accurate Liquid Transfer

Easy-to-Use Transfer Pipettes for Laboratory Applications

Reliable Transfer Pipettes for Scientific Experimentation

Digital Scale:

Accurate Digital Scale for Precise Measurements

High-Quality Digital Scales for Various Applications

Versatile Digital Scales for Home, Kitchen, and Laboratory Use

How to use them and where:

Disposable Lancet:

Usage: Clean the finger with an alcohol swab. Twist off the cap of the lancet. Press the lancet firmly against the fingertip and activate it. Dispose of the lancet properly.

Where: healthcare facilities, diabetic patients at home.

Pipette Tip:

Usage: Attach the pipette tip to the pipette. Immerse the tip into the liquid to be transferred. Depress and release the plunger to draw or dispense the liquid.

Where: laboratories, medical facilities, research institutions.

Packing Envelope:

Usage: Insert items/documents into the envelope. Seal the envelope securely using the adhesive strip. Address and affix postage if needed.

Where: offices, shipping departments, postal services.

Storage Box:

Usage: Place items to be stored inside the box. Close the lid securely. Stack boxes for efficient storage.

Where: homes, offices, warehouses.

Transfer Pipette:

Usage: Squeeze the bulb of the pipette to draw liquid. Release the bulb to transfer the liquid into the desired container. Dispose of or clean the pipette after use.

Where: laboratories, medical facilities, scientific research centers.

Digital Scale:

Usage: Place the object to be weighed on the scale's platform. Read the weight displayed on the digital screen. Adjust the settings as needed.

Where: kitchens, laboratories, retail businesses.

[yueyimold]

256cav disposable micro pipette tips mold

China quality medical mold maker, offer filter tips mold, white tips mold, micro tips mold, plastic micro pipetters mold, disposable lab tips mold.

[eakan2024]

1250ul Filter Tips

1250ul filter tips are often used as 1000ul extra leng tips in lab research. Extra-long filter tips are the perfect solution for professionals who require accuracy and precision in their laboratory work. These tips are designed to fit securely on any pipette, and their extended length provides an added level of safety during handling. The filter ensures that no liquids or aerosols contaminate the sample, and any potential cross-contamination is prevented during use. These disposable tips are made from high-quality materials, providing consistent results every time. They are ideal for use in research, clinical, and diagnostic applications. Overall, 1250ul extra-long filter pipette tips are a reliable and efficient tool that can help maximize your productivity and minimize errors in your lab work.

Specifications of 1250ul Filter Tips

Cat.No.

Name

Color

Volume

Length

Filter

Sterile

Packaging

CS

Compatible

CT1000A-0-TF CT1000A-1-TFS

1000ul Extra Long

Filter Tips

(1250ul Filter Tips)

Natural Color

1000uL

102.00mm

Y

Optional Y

Bulk: 1000 Tips/Bag Racked: 96 Tips/Rack

5000/CS 4800/CS

Eppendorf®/ Thermo®/ Gilson®/Nichiryo®/ Oxford®/ Socorex® etc.

[liquidhandlingproduct]

Choosing the Right Liquid Handling Instruments for Your Lab

Liquid handling is a critical aspect of laboratory work, and having the right equipment is essential to ensure precision, accuracy, and efficiency in your experiments. In this blog, we'll explore the various types of liquid handling instruments, systems, machines, and components available to help you make informed decisions for your lab.

Understanding Liquid Handling Equipment

Liquid handling equipment encompasses a wide range of tools and devices designed to manipulate liquids in a laboratory setting. These instruments are used in various applications, including sample preparation, drug discovery, genomics, and diagnostics. Let's delve into the key categories of liquid handling equipment:

Liquid Handling Instruments

These are the workhorses of any lab, including pipettes (both manual and electronic), dispensers, burettes, and repeaters. When selecting liquid handling instruments, consider factors such as the volume range you'll be working with, precision requirements, and ergonomics for user comfort.

Liquid Handling Systems

For high-throughput and automated tasks, liquid handling systems offer speed and consistency. These systems often include robotic arms, plate handlers, and integrated software to perform complex liquid handling tasks with minimal human intervention. They are ideal for labs with large-scale operations.

Liquid Handling Machines

Liquid handling machines are specialized instruments designed for specific tasks, such as liquid chromatography or liquid handling in DNA sequencing. They are engineered for precise control and accuracy in their intended applications.

Liquid Handling Components

To customize your liquid handling setup, you can choose from a variety of components, such as disposable tips, reservoirs, and adapters. These components play a crucial role in optimizing the performance of your instruments.

Selecting the Right Equipment

When choosing liquid handling equipment for your lab, consider the following factors:

Application - Determine the specific tasks and applications your lab performs. Different instruments may be required for sample preparation, assay development, or high-throughput screening.

Volume Range -  Assess the range of liquid volumes you'll be working with. Some instruments are better suited for microliter quantities, while others handle larger volumes.

Accuracy and Precision - Precision is vital in scientific experiments. Ensure that the equipment you choose meets the required precision and accuracy standards for your work.

Throughput - Consider the throughput requirements of your lab. High-throughput labs benefit from automation and liquid handling systems.

Ergonomics - User comfort and ergonomics should not be overlooked. Instruments that reduce the risk of repetitive strain injuries can improve lab productivity and employee satisfaction.

Cost and Maintenance - Evaluate the initial investment, ongoing maintenance costs, and availability of spare parts when making your decision.

Conclusion

Selecting the right liquid handling equipment, whether it's instruments, systems, machines, or components, is essential for the success of your lab's experiments and research. Take the time to assess your lab's specific needs and requirements, and invest wisely in the tools that will enable you to achieve accurate and efficient liquid handling in your scientific endeavors. With the right equipment, you can enhance the quality and reliability of your results while optimizing your lab's productivity.

[microlitseo]

What advantages does using a pipette have?

When using a pipette, know that it offers several advantages. If talking specifically, this is an important liquid handling instrument in scientific and medical settings where precision and accuracy holds supremacy. 

Here are some key benefits of using pipette:

Precision and Accuracy

Pipettes are designed to measure and transfer small volumes of liquid, keeping in mind the precision and accuracy of each measure. This ensures that experiments and tests signify reliable and reproducible results at all times. 

Efficiency

With the use of pipettes, you can make quick and efficient transfer of liquids. It is going to save a lot of time compared to other methods, which is especially important in high-throughput laboratories. More so, these are where the samples are processed daily. 

Versatility

There are various types of pipettes, such as single-channel, multi-channel, and electronic pipettes. Each type can be used for different applications, from simple liquid transfers to complex experimental protocols.

Minimized Contamination

Using pipettes with disposable tips reduces the risk of cross-contamination between samples. This is vital in experiments where purity is essential, such as in molecular biology or microbiology.

Ergonomics

Modern pipettes are designed, keeping in mind the user's comfortability. They are lightweight and ergonomically shaped to reduce hand strain and fatigue. Thus, enhancing the process of liquid handling technique, which is beneficial for lab technicians who use them frequently.

Cost-Effective

While precision instruments, pipettes are generally cost-effective, especially considering the accuracy and efficiency they provide. This makes them an economical choice for laboratories of all sizes.

Consistency

The use of pipettes ensures consistent liquid handling, which is important for maintaining the integrity of experimental procedures. Furthermore, being able to maintain consistency helps in achieving reliable results, reducing variability in data. 

Easy Calibration and Maintenance

Most pipettes are easy to calibrate and maintain, ensuring their long-term accuracy and functionality. Regular calibration helps maintain their performance and reliability.

In summary, pipettes and its various types are significant tools in many scientific and medical applications, providing precision, efficiency, and versatility. Henceforth, their ability to deliver consistent and accurate liquid handling makes them essential for any laboratory setting.

[sharpsafe]

Waste Containers Supplier

We offer a wide selection of cost-effective indoor and out of doors waste receptacles appropriate for every industry. Under these rules, solid-regulated medical waste could be positioned in red liner baggage as lengthy as they're closable and leak-proof. Liquids and sharps should be placed in thick liner baggage, and then placed inside rigid, puncture-resistant, and leak-resistant dont approved containers. Did you understand that on common, folks now spend roughly thirteen years of their lives at work?

When you employ a service supplier, you don’t want to fret about your containers at all—they care for all of the dirty work. Our merchandise are sustainably manufactured, packed, and shipped from our backyard to yours. Our full-service methodology support is fastidiously manufactured to spice up your program’s success. No one desires to deal with trash, nevertheless it have to be contained and hauled away. Out of sight and out of thoughts are our objectives, and  meets these challenges with probably the most convenient and sturdy carts available on the market - sharps disposal bins.

These internal packages may be reused if they're accredited and permanently marked for reuse, disinfected between each use, and have a capability between two and forty gallons. If you've a small quantity or one type of regulated medical waste, you presumably can comply with the DOT tips for non-bulk packaging. Available in spherical, half spherical and square shapes with grey, white, yellow, darkish blue, pink, black, brown and green shade choices. Features embrace hinged lids, strengthened rims, built in handles, dent, crack, rust, chip, peel  resistant, non slip lifting and anti jam nesting. Suitable for lunchrooms, hallways, resort lobbies, restrooms, shopping malls, restaurants and snack areas - sharps disposal containers wholesale.

Available in different sizes and containers as a lot as are at all times out there. Includes 2-inch central water drain within the base with locking plug  + the smooth inside and outside surfaces of the waste container allow for straightforward cleansing. Used for disposal of needles, syringes, vacutainer, pen needles, lancets, blades, pipettes and glass slides. Manufacturer and distributor of reusable organic waste containers for sharps, diapers, dirty linens, cytotoxic supplies, prescription drugs, needles, blades, and syringes. For more information, please visit our site https://sharpsafe.com.au/