#homogenizer

[kalvierp]

[genizer-homogenizer]

Essential Maintenance Tips for High-Pressure Homogenizers: Keep Your Equipment Running Strong

Regular maintenance is the backbone of reliable performance when it comes to high-pressure homogenizers. Consistent upkeep not only extends the lifespan of your machine but also ensures it operates safely and efficiently. Here’s what you need to know: 1. Perform Daily Visual ChecksStart each day with a quick inspection. Look for leaks, signs of wear, or anything unusual during startup. Ensure…

[genizer-llc]

NanoGenizer Lab Homogenizer for Cell Disruption NanoGenizer High Pressure Homogenizer for Nanomaterials NanoGenizer, a lab-scale microfluidic high pressure homogenizer, offers effective performance on particle size reduction and cell disruption. It utilizes interaction high-pressure microfluidic jet technology, and equipped with highly modular power and processing units. NanoGenizer is suitable for rare and valuable samples because of its minimum dead volume design and its continuous flow rate, which enables it to process up to 120 mL/min. With successful applications in various nanotechnology settings, the NanoGenizer has gained increasing recognition due to its notable shear rate, excellent repeatability, and guaranteed scalability.   NanoGenizer provides efficient solutions for various nanomaterials, including: liposomes, nano-emulsions, nano-crystals, micelles, lipid nanoparticles, cosmetic nano-encapsulation materials, nano-particle dispersion, graphene, carbon nanotube, and more. As more organizations recognize this, NanoGenizer is becoming an essential high pressure homogenizer for laboratories working on high-end nanomaterial preparation.

Core Technology: Interaction Chamber with Microfluidic Jet NanoGenizer can be divided into a power unit (including the power system, control system, and high-pressure pump system) and a processing unit (including the microfluidic diamond interaction chamber, material inlet and outlet, and heat exchanger). The diamond interaction chamber is a reaction component with a specially-designed fix geometry, where high pressure, high speed micro-jets occur and samples are processed. After being pressurized and accelerated by the intensifier, the sample’s micro-jet can reach speeds of 1,000 m/s, faster than the speed of sound (340 m/s). When the high-speed bullet-type micro-jet passes through the diamond interaction chamber’s micro-channels, it undergoes complex physical effects, such as high-frequency shearing, high-energy impact, cavitation and pressure drop, and more. After that, the material is homogenized and nano-sized.   The diamond interaction chamber is the core area where the high-speed micro-jet, high-shear, high-energy collision, and other effects occur. It has fixed Y- or Z-shaped diamond micro-channels inside, which guarantees a consistent effect: accurate and repeatable particle size distribution.

Features of the NanoGenizer High Pressure Homogenizer High Shear Rate After being pressurized by the power unit, the liquid or solid-liquid mixture sample’s micro-jet can reach speeds up to 1,000 m/s inside the diamond interaction chamber (DIXC). The minimum dimension of the inside of the DIXC can be as small as 50 μm. As shown in Figure 4, the NanoGenizer’s shear rate is the highest among comparable technologies.

The NanoGenizer high pressure homogenizer’s shearing force on the material is unmatched by conventional homogenizers or other homogenizing equipment.   Fixed Internal Structure and Consistent Reaction Pressure

The diamond interaction chamber has a fixed internal shape (Figures 5 and 6) and does not move with pressure changes. When the sample passes through the DIXC, the applied pressure is at a constant peak during each cycle’s process (see the blue curve in Figure 7). However, the traditional homogenizing valve has a dynamically adjustable structure. The pressure of the material changes dynamically when it passes through a conventional homogenizer’s valve, which operates at peak pressures for mere moments of each cycle (the black curve in Figure 7). The particle size of the material processed by the microfluidic diamond interaction chamber is reduced efficiently, and the distribution is more uniform than can be achieved with a traditional homogenizing valve.

Interaction Effect The design of the Y-type DIXC takes full advantage of the interaction collision of the materials themselves. The instantaneous relative velocity of the two jets is doubled, resulting in an explosion effect. The collision between the materials greatly reduces the materials’ wear and shear to the interaction chamber, prolonging the chamber’s service life and avoiding the risk of stainless steel particles falling off.  The patented DIXC-RT with cooling function (see Figure 3) protects the bioactivity of the samples.   Guaranteed Scalability 

The single-slotted DIXC (shown in Figure 2 and Figure 3) is suitable for lab-scale high pressure homogenization equipment. The multi-slotted DIXC (shown in Figure 8 and Figure 9) is composed of multiple diamond micro-channels copied in parallel, ensuring the treatment effect’s consistency. The increased number of channels also allows for larger volumetric flow rate.   Genizer LLC is one of two companies in the world that supplies high pressure homogenizers equipped with original microfluidic diamond interaction chambers. In recent years, Genizer’s microfluidic diamond interaction chambers have been equipped by more and more homogenizer manufacturer.   Easy to Operate and Intelligent The highly modular and integrated control design of NanoGenizer makes it extremely simple to install and operate. Operators can complete routine operations by clicking the three buttons—"pressure rate,” “start,” and “stop”—on the touch screen. Customers find the equipment simple to operate: They only need to set a pressure on the screen and then click to start or stop. There is no need to screw the valve forcefully or waste any sample to adjust the pressure. To process a particularly small volume, you can set the sample volume processed by one stroke, the stroke cycle times, and the automatic stop time on the setup interface. Compared with other high pressure equipment, the NanoGenizer’s operation is elegant and efficient.

Small Minimum Sample NanoGenizer’s highly modular design enables simple installation and maintenance. The dead volume is no more than 1 mL, far below the dead volume of other high pressure homogenizers, which is typically more than 10 mL. Therefore, when a 10 mL sample is processed in traditional homogenizers, it is almost impossible get product from the outlet. NanoGenizer's modular pipeline design can achieve a minimum single processing volume of 5 mL by setting the volume autonomously, making it the best equipment option for preparing and developing rare, costly samples. NanoGenizer’s continuous flow rate is 7 L/h, suitable for conventional small batches.   Software and Hardware Options Temperature Control: Jacketed interaction Chamber; jacketed inlet cylinder; 3D heat exchanger Suspension Preparation: Hollow magnetic stirrer Corrosion Resistance: Titanium cylinder option Precision Sampling: Precision sampling as accurate as 0.1 mL (e.g., 10.0mL, 10.1mL, and 10.2mL sampling are all possible) Ports: Data log, USB port, and multi-sensor ports for temperature and pressure     Scientific researchers who have used NanoGenizer are impressed by its high processing efficiency, easy operation, and intelligent control. NanoGenizer is currently the one of the most selected homogenizers for nanomaterials in the world.

[tipcoengineer]

An industrial homogenizer machine is a powerful piece of equipment designed to uniformly mix two or more substances that typically don’t blend easily, like oil and water. It uses mechanical force, high pressure, or ultrasonic energy to break down and distribute particles evenly, creating a stable, homogeneous product.

[high-pressure-homogenizer]

High-Pressure Homogenization: A Solution For Carbon Nanotube Dispersion

HPH offers a powerful solution for dispersing CNTs by applying intense pressure (up to 45,000 psi) to break up CNT aggregates. During the process, a fluid containing CNTs is forced through a narrow orifice at high speeds, generating extreme shear forces that separate the nanotubes and create a uniform dispersion. The Genizer high-pressure mcirofluidic homogenizer is a notable example of equipment designed to achieve this level of dispersion effectively.

Advantages of HPH for CNT Processing

The primary advantage of HPH is its ability to achieve consistent dispersion across large volumes. This uniformity is crucial for applications where the precise arrangement of CNTs is necessary, such as in nanocomposites, electronics, and coatings. Additionally, HPH enables the scaling of CNT processing, making it feasible for both research and industrial production. 

High-pressure homogenization has revolutionized the way carbon nanotubes are processed, ensuring efficient, scalable, and consistent dispersions. As industries continue to explore CNTs' potential, HPH will play a key role in enabling their full application across various fields.

[idexindia]

Lower Costs, Higher Shear: Introducing the Quadro® HV High Shear Homogenizer

In today’s fast-paced industries, efficient, precise, and cost-effective processes are essential. Whether in pharmaceuticals, food, cosmetics, or industrial applications, managing submicron emulsions and suspensions requires advanced solutions. Traditional high-pressure homogenizers or media mills often come with high capital costs and inefficiencies. That’s where the Quadro® HV High Shear Mixer Homogenizer excels, offering cutting-edge technology to deliver unmatched high shear mixing and wet milling without the need for expensive high-pressure systems.

[emmarobinsonsworld]

Handheld Homogenizer

Labtron Handheld Homogenizer is a high-shear, ultra-fine emulsifier with speeds from 5000 to 35,000 rpm. It features a portable design, easy-to-clean detachable SS316 stainless steel heads, and generates powerful liquid shear force for efficient emulsification.

[moreshine]

Moreshine Coffee milk homogenizer homogenizer mixer cosmetic ultrasonic ...

[fpaultrasonic]

در این متن توضیح داده ایم که التراسونیک هموژنایزر چیست، چه کاربردهایی دارد و چگونه می تواند به شما در توسعۀ کسب و کارتان کمک کند.

[goma-engineering-blog]

A Systematic and sturdy technology build by Goma Engineering for High-Pressure homogenizing process with its applications spread across various segments of the diverse industries.

[jerseymuppet]

getting up on my soapbox for a moment. i find it laughable that nearly every time someone says they don’t like rap they cite hamilton and k-pop as the only rap they can tolerate. because everything else is just so violent and full of blatant consumerism. first off. so is k-pop. secondly. idk how to tell you the founding fathers were some of the most violent people around (coming from a black american descentant of slaves who is most likely related to thomas jefferson. shouldn’t have to explain the relevance here). thirdly. hamilton and k-pop both reference and interpolate rap. so idk what to tell you babes. you do like rap. you just don’t like black people. say it with your full chest next time.

[wisdomfish]

Resists and defies

The historic Christian faith consistently resists and defies all attempts to homogenize and mythologize its central truth-claims. The apostles saw Jesus’ resurrection from the dead and reported it as an historical-factual event.

The Fact of Christ’s Resurrection [1 Corinthians 5:1-8]

“Now brothers and sisters, let me remind you [once again] of the good news [of salvation] which I preached to you, which you welcomed and accepted and on which you stand [by faith]. By this faith you are saved [reborn from above—spiritually transformed, renewed, and set apart for His purpose], if you hold firmly to the word which I preached to you, unless you believed in vain [just superficially and without complete commitment].

For I passed on to you as of first importance what I also received, that Christ died for our sins according to [that which] the Scriptures [foretold], and that He was buried, and that He was [bodily] raised on the third day according to [that which] the Scriptures [foretold], and that He appeared to Cephas (Peter), then to the Twelve. After that He appeared to more than five hundred brothers and sisters at one time, the majority of whom are still alive, but some have fallen asleep [in death]. Then He was seen by James, then by all the apostles, and last of all, as to one untimely (prematurely, traumatically) born, He appeared to me also.”

~ Samples, Kenneth Richard. ‘Without a Doubt: Answering the 20 Toughest Faith Questions.; p. 168

[genizer-homogenizer]

Advantages of using High-Pressure Homogenization to process E. coli Cells

High-pressure homogenization is a robust method widely used in biotechnology and pharmaceutical industries for disrupting E. coli cells and extracting intracellular components such as proteins and DNA. This technique subjects the cells to intense pressure and shear forces, efficiently breaking down cell walls to release their contents. Advantages include: Efficiency: It effectively ruptures…

[genizer-llc]

Genizer, located in Technology Link in Greater Los Angeles, is dedicated to advancing homogenizer nanotechnology. We provide high pressure homogenizers, liposome extruders, sanitary heat exchangers, diamond interaction chambers, and high pressure gauges compatible with other brands of high pressure homogenizers and high pressure pumps.

[tipcoengineer]

A homogenizer machine is used to reduce particle sizes in a liquid suspension and ensure uniform distribution. It’s widely used to create emulsions and blends, especially where high precision and consistency are required.

[high-pressure-homogenizer]

Genizer Hand Driven High Pressure Microfluidic Homogenizer up to 30,000psi. The Portable Hand-Driven Homogenizer is a cost-effective, lightweight tool for concept testing, reaching pressures up to 30,000 psi. Its compact design enables easy hand operation without compressed gas, making it ideal for small-scale formulations and a versatile alternative to air-driven units. It handles nanodispersions, nanoemulsions, cell disruption, and encapsulation in polymers, liposomes, and oils. The homogenizer can also function as a high-pressure pump for sanitary applications, such as liposome extrusion, with adjustable pressure settings of 10,000 psi, 20,000 psi, and 30,000 psi, and reduced dead volume by replacing the pressure gauge with a plug.