#legones

[legendarytragedynacho]

Lux Interior with The Cramps - Paris - Eldorado - jun 1984

📷 by Bernard Legon

[godsoflust-x]

[noobclock666]

Pico School by @TomFulp

Tankmen series and the Logo by @JohnnyUtah

Madness Combat by @Krinkels and Michel Ancel

Blockhead by @The-Swine

Klay World by @Knox

Thing Thing by @Weasel and John Carpenter

Das n Me by @DanPaladin, @Dustball, and Tom Fulp again.

Alien Hominid by @DanPaladin, @Dustball, and Tom Fulp again again.

FRIDAY NIGHT FUNKIN' by @ninjamuffin99, @PhantomArcade, @evilsk8r, and @KawaiSprite.

Piko Legon by @HorseFolder

…I want more people to make more Rule 34 of her

Tarman by James Lee and Allan Trautman

Flumpty Bumty and Birthday Boy Blam by @JonBro

(They are technically not Newgrounds characters, but they will be when he uploads them here)

Fish Girl by @DeadlyComics

Edd Egg by @Eddache

Henry stickmin by PuffballsUnited

Strawberry clock by himself

Toss the Saled by @Foreverkul and @Gonzossm

Dead Baby by @Bluebaby

Empty Cup by @Diives

It's a cup, not a cub.

Among us by @PuffballsUnited again, @ForteBass, and John W. Campbell.

Space Invaders by Tomohiro NYouTube. CRAP! I miss the name! Too late. I just want to go to bed

Zone Tansalon by @ZONE-SAMA

Tom from Tom tells of whatever by @eddsworld RIP

Rage Melon by @Sexual-Lobster

It's nighttime and I should really go to bed!

Fancy Pants by @DrNeroCF

They're all great! Give them some love!

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[thousandsaresailing]

ghana

[xtruss]

Virginia Tech Scientist Shows Focused Ultrasound Can Reach Deep Into The Brain To Relieve Pain

A Study by Wynn Legon, assistant professor at the Fralin Biomedical Research Institute at VTC, found that narrowly focused soundwaves aimed at an area of the brain called the insula reduced both the perception of pain and the body’s reaction to it.

— By Matt Chittum | 5 February 2024

Wynn Legon, Assistant Professor at the Fralin Biomedical Research Institute at VTC, authored a paper published in the journal PAIN that is the first to demonstrate low-intensity focused ultrasound can penetrate a deep part of the brain called the insula and relieve both pain and the body’s response to the stress caused by it. Photo by Clayton Metz for Virginia Tech.

You feel a pain, so you pop a couple of ibuprofen or acetaminophen. If the pain is severe or chronic, you might be prescribed something stronger – an opioid pain killer that can be addictive under some circumstances.

But what if you could ease pain by noninvasively manipulating a spot inside your brain where pain is registered?

A new study by Wynn Legon, assistant professor at the Fralin Biomedical Research Institute at VTC, and his team points to that possibility. The study, published in the journal PAIN on Feb. 5, found soundwaves from low-intensity focused ultrasound aimed at a place deep in the brain called the insula can reduce both the perception of pain and other effects of pain, such as heart rate changes.

“This is a proof-of-principle study,” Legon said. “Can we get the focused ultrasound energy to that part of the brain and does it do anything? Does it change the body’s reaction to a painful stimulus to reduce your perception of pain?”

Focused ultrasound uses the same technology used to view a baby in the womb, but it delivers a narrow band of sound waves to a tiny point. At high intensity, ultrasound can ablate tissue. At low-intensity, it can cause gentler, transient biological effects, such as altering nerve cell electrical activity.

Neuroscientists have long studied how nonsurgical techniques, such as transcranial magnetic stimulation, might be used to treat depression and other issues. Legon’s study, however, is the first to target the insula and show that focused ultrasound can reach deep into the brain to ease pain.

The study involved 23 healthy human participants. Heat was applied to the backs of their hands to induce pain. At the same time, they wore a device that delivered focused ultrasound waves to a spot in their brain guided by magnetic resonance imaging (MRI).

Participants rated their pain perception in each application on a scale of zero to nine. Researchers also monitored each participant’s heart rate and heart rate variability – the irregularity of the time between heart beats – as a means to discern how ultrasound to the brain also affects the body’s reaction to a painful stimulus.

Participants reported an average reduction in pain of three-fourths of a point.

“That might seem like a small amount, but once you get to a full point, it verges on being clinically meaningful,” said Legon, also assistant professor in Virginia Tech's School of Neuroscience. “It could make a significant difference in quality of life, or being able to manage chronic pain with over-the-counter medicines instead of prescription opioids.”

The study also found the ultrasound application reduced physical responses to the stress of pain – heart rate and heart rate variability, which are associated with better overall health.

“Your heart is not a metronome. The time between your heart beats is irregular, and that’s a good thing,” Legon said. “Increasing the body’s ability to deal with and respond to pain may be an important means of reducing disease burden.”

The effect of focused ultrasound on those factors suggests a future direction for the Legon lab’s research – to explore the heart-brain axis, or how the heart and brain influence each other, and whether pain can be mitigated by reducing its cardiovascular stress effects.

— Other authors on the paper include Andrew Strohman, an M.D./Ph.D. student in the Virginia Tech Carilion School of Medicine and Virginia Tech’s Translational Biology, Medicine, and Health Graduate Program, and other Legon Lab members.

— The study was supported by the Seale Innovation Fund, the Focused Ultrasound Foundation, and the National Institutes of Health.

The brand new 139,000-square-foot Biomedical Research Addition provides state-of-the-art research laboratories that focus in six thematic areas of research: Biomaterials and body-device interfaces, Neuroscience, Cardiovascular Science, Comparative Oncology, Infectious Disease and Immunity (COVID-19 Research), Metabolism and Obesity

These facilities will be home to 25+ new research teams by 2027. The new space already houses an active cardiovascular research lab, a brain cancer research lab, a high-field magnet for brain and heart imaging, and the veterinary college’s new Animal Cancer Care and Research Center. The expansion also includes Virginia Tech’s COVID-19 testing laboratory, and a new biological safety level three facility where our researchers will work on identifying the mechanisms of COVID-19-induced disease and therapeutics.

In addition, the Fralin Biomedical Research Institute and Virginia Tech are expanding research operations to the Children's National Research & Innovation Campus in Washington, D.C. The new laboratories in D.C., anticipated to open in 2021, will be home to a team of Virginia Tech scientists who will work alongside researchers and clinicians at Children's National and JLabs to develop new diagnostics and therapeutics to treat pediatric nervous system cancers.

[archornews]

Watch as thieves craftily steal delivery vans in East Legon.

Social media buzzing over how two thieves smartly stole two delivery motorbikes in East Legon in the Capital of Ghana. This follows a CCTV footage which captured the two thieves in the act. The first of the two thieves was bold enough and pick the bike with such confidence that you will conclude that he is the owner. The second thief was a bit careful and did everything to concealed his face from…

[the-greens]

Estate Developer in Ghana

The estate development business in Ghana is growing popular in the past few decades. It has attracted many buyers globally, especially from the UK, the USA, Canada, etc. Many successful estate developers in Ghana have accomplished the clientele’s needs by providing them with high-end real estate projects with a good return on investment.

[stevepasztor]

[abrantepakjunyor]

Watch the GPL highlights of the draw between Asante Kotoko and Legon Cities. In game 7 of the Ghana Premier League, Asante Kotoko was unable to capitalize on their home field advantage against Legon Cities. After a 1-1 draw with Legon Cities on Wednesday at the Baba Yara Stadium, the Porcupine Warriors were unable to continue their winning streak. After just 14 minutes of the eagerly awaited…

[edulearnweb]

Presec Legon Mounts Gaint 7th NSMQ Triumph "We Are SEVEN A Living God" signage

Presec Legon Mounts Gaint 7th NSMQ Triumph “We Are SEVEN A Living God” signage

Presec Legon has mounted a giant “We Are SEVEN A Living God” signage after their 7th NSMQ Trophy and triumph over Prempeh College and Adisadel College in the finals of the Quiz held on 26th October 2022. The Presbyterian Boy’s School in Legon remains the most decorated school in the 29-year history of the National Science and Maths Quiz haven set the 6th time winners record in 2020, and now the…

[newshuntermag]

I Am Selling My Virg*nity For GHS 5,000 – 22-Year-Old Student Of Legon Shockingly Discloses

I Am Selling My Virg*nity For GHS 5,000 – 22-Year-Old Student Of Legon Shockingly Discloses

A 22-year-old student of the University of Ghana (Legon) has shocked many people. She disclosed that she is selling her virg*nity for GHS 5,000. The young lady who claims to be beautiful said she will be with the buyer for one month. She said a lot of men wanted her in the past, but she did not accept them. The lady, a third-year student at Legon, described her features in the…

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Asamoah Gyan opens up on why he failed at Legon Cities

Asamoah Gyan opens up on why he failed at Legon Cities

Ghana’s all-time leading goal scorer, Asamoah Gyan, has blamed persistent injuries for his struggle at Legon Cities. The 36-year-old made a return to the Ghana Premier League before the start of the 2019/20 football season and signed a one-year deal with the Royals. In an interview on the Dentaa Show, the ex-Ghana captain stated that niggling injuries stopped him from enjoying his second stint…

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