#measles and sspe

[fidicusraredisease]

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Precautions, neglect Complications SSPE, Subacute Sclerosing Panencephalitis | Treatment Cure Relief | Rare Orphan Unique Disease | Dr. Bharadwaz

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Fidicus Rare Disease

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About Video : Diving into SSPE, let's navigate through essential precautions and prognosis means what happens when you neglect this disease. Explore crucial steps to safeguard against SSPE, understanding the disease's trajectory and potential outcomes. Gain insights into preventive measures, prognosis factors, and proactive approaches for managing this challenging condition. Empower yourself with knowledge for a better understanding of SSPE's journey.

[tomorrowusa]

Anybody who hasn't gotten the MMR vaccine needs to get it ASAP.

Thanks to anti-vaxxing pseudoscience propaganda, there's a measles outbreak in Texas – as well as smaller outbreaks where clusters of conspiracy freaks discourage vaccinations.

Some people who haven't paid attention to medicine for the past 60 years may dismiss it as just a "childhood disease". But measles can be a lot worse than just spots and a fever. Measles can kill you.

Measles outbreaks spark concern over rare 'horrific' neurological disorder

Pediatricians and scientists say they are also watching for extremely rare neurological conditions that can occur even years after children who've had measles recover from it. [ ... ] On Friday the U.S. Centers for Disease Control and Prevention reported 712 cases of measles so far this year in 25 jurisdictions, including Texas and New Mexico. In Gaines County, Texas, the centre of the outbreak, measles counts on Friday rose to 355, up from the 328 reported on Tuesday, the Texas Department of State Health Services said. The federal agency said 97 per cent of U.S. measles cases are individuals who are either unvaccinated or have an unknown vaccination status. [ ... ] The measles virus causes a high fever, but it also suppresses the immune system.  "The lining of the airway gets affected and it becomes an ineffective barrier," [Dr. Michelle] Barton said. "In the face of this virus, which is very what we call immunosuppressive, you can end up with pneumonia." She noted that ear and other secondary infections are also common. [ ... ] More serious complications include swelling of the brain or encephalitis in about one in 1,000 cases, which can lead to drowsiness, confusion and seizures that resolve, Barton and [Dr. Dele] Davies said.  While they are extremely rare, long-term neurological problems can occur even after a young child has recovered from measles.  Barton says the measles virus itself stays at a low level in the brain and can wake up six to 10 years later as a devastating disorder called subacute sclerosing panencephalitis, or SSPE. [ ... ] Immunologist Dawn Bowdish, a professor of medicine at McMaster University, says the measles virus has mutations that allow it to hide out from the immune system, then move from neuron to neuron where the parts of the brain required for cognition and movement can be damaged.  "It starts with challenges in learning or memory," Bowdish said. "They don't reach their full intellectual potential …  something no parent wants for their child." Those with SSPE can have seizures. Medical experts say that in almost all cases, the disorder progresses until the patient is in a vegetative state, and it eventually ends in death.

The anti-vax conspiracy crazies falsely claim that the MMR vaccine causes autism. Yet they haven't been able to point to a single case of autism caused by the vaccine.

On the other hand, it's been known for a long time that measles in some can lead to SSPE which leaves patients in a vegetative state and then ultimately kills them.

[corporalkiheart]

Immunity reset actually isn’t the scariest thing that measles does. That dubious honour belongs to subacute sclerosing panencephalitis, which can occur (thankfully relatively rarely) after a measles infection.

Following a period of asymptomaticity, there begins a progressive neurological decline, which includes confusion, personality changes, seizures, paralysis, and eventually death. There is no cure for this. Death is the inevitable outcome within a few years.

This occurs largely in children, but can occur in adults. In those old enough to understand what is happening, it’s terrifying - your abilities are slipping away from you, your mind is no longer clear, and you know you’ll die shortly no matter what is done.

So fuck antivaxxers. We almost eradicated this one worldwide but no, we had to have active misinformation campaigns kicked off by one guy who wanted to make money of HIS vaccine and to do so worked to discredit all other vaccines.

Also, it’s not just “rich white women”. A lot of the time it’s the dads refusing vaccines (and I work in an area where many women will submit to their husband’s will, even if they disagree), and anti-vax misinformation is often specifically targeted towards lower income and minority groups (see the measles outbreak in Samoa, which was secondary to a drop in vaccinations specifically and intentionally spurred on by RFK Jr).

VACCINATE YA KIDS FFS

[willowreader]

I am seeing so many posts about measles. I had the red measles when I was 6. I was extremely sick, and had to stay in a dark room, because my mother was trying to protect me from going blind.. Some children who contracted measles became deaf. There were children who died right after the infection, or years later, after contracting the fatal neurological syndrome SSPE. Roald Dahl, a children's author, wrote this letter about his precious daughter. She died at age 7 from measles. Children must get vaccinated for measles.

[saywhat-politics]

You think measles is benign until you've seen a case of SSPE - an incurable complication of measles which causes kids to develop dementia, seizures and death.

It's preventable by the vaccine.

Anti vaxxers are deadly.

And now they are in charge. - Dr. Neil Stone

[captainpookie338]

Measles will deny your male child the right to create babies. It causes sterility.

Measles will take your happy health child and give them irreversible brain damage.

It can take your child who can see and hear and drown them in darkness and silence. It takes the light from their eyes.

It can take your healthy child and cause them to die horribly via sspe. It's fatal. 2 out of 10000 unactivated children and adults and 1 out of 609 babies under 15 months who can not be vaccinated.

It maims, it kills, it leaves children husks.

All because people are too fucking stupid to trust the science and get their kids vaccinated.

Because fuck those little ones who can't get vaccinated. They aren't MY babies.

If you think autism is the worst thing to happen to a child, then you live in a fantasy world.

Vaccines don't cause Autism.

So I reblogged that “vaccines cause adults” post from @copperbadge and predictably my inbox has gone to shit with a handful of people asking me how I can “trust” vaccines and if you’re looking for me validate your fear mongering over vaccines causing autism, I’m afraid you’re in the wrong place.

I’m the bitch that has anaphylactic reactions to vaccines due to my mast cell disorder and still turn up for my Covid booster shots with my epi pen in one hand and a fistful of Benadryl in the other.

I had reactions to all my MMR boosters and every other booster I’ve ever needed and I still show up because I look at the choices and I prefer the risk of potential immediate death over potentially getting shit like measles and spreading it to the wider community.

The only one I don’t get is the flu shot because the speed at which I react is terrifying and it’s in my file that I’m not allowed it anymore. Doctors made that decision for me, I didn’t.

My MCAS might make me a crunchy hippy dippy bitch against my will, but I’m a science based crunchy hippy dippy bitch and vaccines do not cause autism.

Measles will fucking kill your kid though.

[3acesnews]

What Is SSPE? The Devastating Complication Of Measles That Hits Years Down The Road

[printedword]

On May 4, 2005, a seventeen-year-old unvaccinated Indiana girl boarded a plane to Bucharest, Romania. Sent on a mission by her church, she visited an orphanage and a hospital. She didn’t know that Romania was in the midst of a measles epidemic. On May 14, on the plane back to Indiana, she developed fever, cough, runny nose, and pink eye. The next day, she went to a church picnic attended by five hundred people. Although she felt ill, she was excited to share her experiences with her friends and neighbors. Neither she nor anyone at the picnic knew she had measles. On May 16, a red, speckled rash appeared on most of her body. On May 29, two weeks after the picnic, the Indiana State Health Department received a phone call from a doctor in Cincinnati who recently had admitted a severely dehydrated six-year-old boy to the hospital. His diagnosis: measles. The doctor called health officials to tell them where the boy had been two weeks earlier: a church picnic in Indiana. The subsequent investigation was a case study in just how contagious measles virus can be. Among the 500 people at the picnic, 35 had never received a measles vaccine — 31 of them (89 percent) became infected. Of the remaining 465 people, only 3 (0.6 percent) were infected. The girl who had contracted measles in Romania — after spending only a few hours in a crowd of 500 people — had managed to infect almost every person susceptible to the disease. The Indiana outbreak was a frightening reminder of our past. Before 1963, when a vaccine was first available, measles was a common cause of suffering and death. Although most parents know that measles virus causes a rash, few know that it can also travel to the lungs and cause pneumonia or to the brain and cause inflammation (a condition called encephalitis), often resulting in seizures and brain damage. Worst of all, measles virus causes a rare disease called SSPE (subacute sclerosing panencephalitis), whereby children become progressively less able to walk, talk, or stand. Invariably, they develop seizures, lapse into a coma, and die; despite heroic supportive measures, no child has ever survived SSPE. Before the vaccine, measles infected as many as four million American children, causing a hundred thousand to be hospitalized and five hundred to die every year.

— Paul A. Offit, from Deadly Choices

[fidicusraredisease]

Call : +917997101303 | Whatsapp : https://wa.me/917997101505 | Website : https://fidicus.com

What is SSPE? or Subacute Sclerosing Panencephalitis or Dowson Disease - Homeopathy | Treatment Cure Relief | Rare Orphan Unique Disease | Dr. Bharadwaz

Speciality Clinic

Fidicus Rare Disease

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About Video : In this video, we explore Subacute Sclerosing Panencephalitis (SSPE), a rare but fatal brain disorder. Learn how SSPE develops as a complication of the measles virus, typically appearing years after the initial infection. We discuss its symptoms, which include behavioral changes, motor dysfunction, and seizures, and highlight the importance of early diagnosis and vaccination in prevention. Join us to understand the medical complexities and the critical need for awareness about SSPE.

[themarchrabbit]

RFK Jr already has a body count thanks to his arrogance. Children, primarily, for the first wave.

"First wave? What do you mean?"

Oh, see measles is not a disease that fucks around. And just because you think it's done, doesn't mean it is.

Severe complications in children and adults

Some people may suffer from severe complications, such as pneumonia (infection of the lungs) and encephalitis (swelling of the brain). They may need to be hospitalized and could die.

Hospitalization. About 1 in 5 unvaccinated people in the U.S. who get measles is hospitalized.

Pneumonia. As many as 1 out of every 20 children with measles gets pneumonia, the most common cause of death from measles in young children.

Encephalitis. About 1 child out of every 1,000 who get measles will develop encephalitis (swelling of the brain). This can lead to convulsions and leave the child deaf or with intellectual disability.

Death. Nearly 1 to 3 of every 1,000 children who become infected with measles will die from respiratory and neurologic complications.

Complications during pregnancy. If you are pregnant and have not had the MMR vaccine, measles may cause birth prematurely, or have a low-birth-weight baby.

Long-term complications

Subacute sclerosing panencephalitis (SSPE) is a very rare, but fatal disease of the central nervous system. It results from a measles virus infection acquired earlier in life.

About SSPE

SSPE generally develops 7 to 10 years after a person has measles, even though the person seems to have fully recovered from the illness.

Since measles was eliminated in 2000, SSPE is rarely reported in the United States.

Among people who contracted measles during the resurgence in the United States in 1989 to 1991, 7 to 11 out of every 100,000 were estimated to be at risk for developing SSPE.

The risk of developing SSPE may be higher for a person who gets measles before they are 2 years of age.

"Okay, but that says that's rare -"

Want to know what else measles does?

"Reporting today in Science, the researchers show that the measles virus wipes out 11 percent to 73 percent of the different antibodies that protect against viral and bacterial strains a person was previously immune to — anything from influenza to herpes virus to bacteria that cause pneumonia and skin infections."

It not only fucks you up, it leaves your system weaker. Your body is organic; the parts need time to heal and recover in between illnesses. That's a little hard to do when measles just knocked the shit out of your immune system, leaving your body vulnerable to follow-up infections.

The people who recover from the illness will potentially feel effects for the rest of their lives. Their communities will feel those effects. That body count will climb. RFK Jr's arrogance has already negatively impacted lives for a generation in Samoa.

Of course, that's the plan for the United States. Anyone who has had the unfortunate luck of having to hold a conversation with the Fail Kennedy knows he actually is just this fucking stupid. But because he's a Kennedy, he's convinced he was born with the divine wisdom of Solomon. This shit isn't an act with him. He genuinely believes he's the smartest person in the room. Doesn't help that everyone in D.C. hates him, and has hated him for three decades. I'm pretty positive the rumor about him being clocked with a three-hole punch in the 80s by a former secretary of President Kennedy's cabinet is actually true.

Medicaid is free. RFK Jr. should slither out of the room on his belly.

[teachingrounds]

Q. What are the possible complications from measles (rubeola)?

A. According to the CDC, complications from measles infection include

- hospitalization (1:5 unvaccinated individuals) - otitis media (1:10) - pneumonia (1:20) - encephalitis (1:1000) - death (1-3:1000) - subacute sclerosing panencephalitis (SSPE) is a delayed neurodegenerative disorder of personality changes, seizures, coma, and death ~10-11 years after infection

[willowreader]

I had the measles in 1959 at the age of 7. I was in a dark room for 2 weeks to help prevent me from going blind. I was very sick. My mom had 3 other children. A 4 year old and 10 month old twins. Kids in Canada were dying. She was terrified. 1 to 2 children in 1000 will die of measles if not vaccinated. There are complications like immune system damage and measle encephalitis. It can also lead to a neurological disease called SSPE that can kill a child years later. Today I read a post from a young mother who has decided that her children have a strong enough immune system to handle measles. My god I feel like screaming. We have good science. We fixed this year's ago. Please listen to us old people who experienced this. Children will die.

This author's daughter died of measles. Read the story and then vaccinate your children if they are not vaccinated for this horrible disease.

[5minpediatrics]

Subacute Sclerosing Panencephalitis (SSPE): Unraveling the 9S Mnemonics for Diagnosis and Management

Subacute Sclerosing Panencephalitis (SSPE):mnemonics     Introduction:Subacute Sclerosing Panencephalitis (SSPE) is a rare and devastating neurological disorder caused by a persistent infection of the measles virus. This article aims to provide a comprehensive overview of SSPE, focusing on the 9S mnemonics as a tool for understanding its pathogenesis, clinical presentation, and supportive…

[itsdoctorhouse]

Paternity

CC: Diplopia, night terrors ongoing 3 weeks, and a myoclonic jerk

Dx: Subacute sclerosing panencephalitis (SSPE)

Diplopia:

aka double vision: the perception of two images instead of a single object

Common causes usually stem from issues with the eyes, muscles and nerves controlling the eyes, and the brain.

Night terrors:

As mentioned in the episode, there are two leading causes for onset teenage night terrors: PTSD and sexual abuse.

Personally I think there isn’t much reason for the patient to have experienced night terrors beyond the initial stages of SSPE causing changes in emotional behavior and personality.

Myoclonic jerk:

Brief, involuntary twitching of some muscles; generally in healthy persons it can be seen right before falling asleep (aka a hypnic jerk).

The patient presents it even though he’s not asleep or tired.

Multiple sclerosis (MS):

In the episode:

After testing some CSF, because of a buildup and blockage, they find high levels of IgG and assume multiple sclerosis, but find no evidence of lesions. A good assumption because over 80% of patients with MS show oligoclonal bands with high IgG.

Since the patients symptoms have only begun 3 weeks previously they determine it’s rapidly progressive MS.

They can’t definitively diagnose MS, because there are no specific tests for it. Generally doctors have to rule out every other possibility before they can confirm. What’s mentioned in the episode is waiting 6 months to confirm, most likely to see progression of symptoms as well as ruling out differentials.

More on Marburg MS s7e08 “Small Sacrifices”

MS is a chronic central nervous system disease in which the myelin sheath and nerve axons in the brain are destroyed. It’s referred to as a demyelinating disease. The damage disrupts the ability to transmit signals which can result in a slew of signs and symptoms.

The three main characteristics are the formation of lesions/plaques in the CNS, inflammation and the destruction of myelin sheaths of neurons

Other specific symptoms usually include diplopia, blindness in one eye, muscle weakness, and trouble with sensation or coordination.

Some pathognomonic signs include:

Internuclear ophthalmoplegia (INO): an impairment in the lateral conjugate gaze, meaning that when both eyes are looking toward one side the affected eye cannot properly adduct (move toward the center). Caused bye a lesion in the medial longitudinal fasciculus (part in the brainstem).

To put it simply, if the right eye is affected, the patient should be able to look to the right, and cross their eyes, but upon looking to the left, the right eye won’t be able to move to the midline.

Positive Romberg’s sign: when the patient sways or falls with their eyes closed. It demonstrates a loss of postural control and proprioception (perception and awareness of one’s body) in the absence of visual input.

Positive Lhermitte’s sign: paresthesia/an electrical shock that passes down the back of the neck and spine, usually brought upon by bending the head forwards towards the chest.

Progression usually occurs as episodes of worsening lasting days to months, followed by improvement (relapsing episodes).

Subacute sclerosing panencephalitis (SSPE):

Early in the episode Cameron admits to not having taken a full history or family history which really would have solved the case a hell of a lot sooner, given his birth mother was the cause of the patients issues.

tbf, it was the whole point of the episode to focus on determining paternity, which, given all the daddy issues on the show is a good setup.

Then again, the patient is a 16 year old lacrosse player, and he figured out he was adopted at a much younger age, 10 if I remember right, just from having a cleft chin. Talk about selective blindness on the team.

aka Dawson disease

SSPE is a super rare complication from measles wherein there is chronic progressive brain inflammation caused by the mutated virus.

Patients generally have history of a primary measles infection in infancy (where the birth mother was not vaccinated and thus could not pass along the proper antibodies to protect the infant for up to 6 months), followed by an asymptomatic period that can last up to 27 years. Afterwards neurological deterioration ensues with behavioral changes, myoclonic seizures, visual disturbances, ataxia, and ultimately death.

Anti-measles IgG appears to increase as the disease progresses

There is no definitive cure, but if it is diagnosed in the first stage of the disease oral isoprinosine and intraventricular interferon alfa could help, it varies patient to patient. And the only accepted treatment are purely supportive: anticonvulsants.

Should not be confused with acute disseminated encephalomyelitis (ADEM), which can also be caused by the measles virus.

Another demyelinating disease, it is a rare autoimmune disease with acute inflammation of the brain and spinal cord.

Often triggered by a viral infection or specific non-routine vaccinations.

Very closely resembles symptoms of MS except for usually occurring in children and marked with rapid fever.

[bottle-of-smoke]

I realise this is brattish of me, but it enrages me how no one has acknowledged how prescient this scene I wrote in How the Light Gets In (IN DECEMBER) is:

“‘You’re not going to get measles,’ Richie soothed. His heart was pumping with an almost erotic violence.

‘How the fuck do you know, Dr Tozier? Have you ever read the complications of measles? You can get pneumonia, or go blind. Have you heard of SSPE? No, of course you haven’t. It’s got an almost 100% fatality rate. And that’s just measles. Remember SARS? That travelled by plane too. No vaccine for fucking SARS.’ Eddie’s voice was becoming progressively more hysterical, as though he was attempting some kind of oral land speed record.

‘You are the only person on the planet still worried about SARS, Eddie.’”

Come on!! >:(