#odontogen

[jcrmhscasereports]

Basal cell carcinoma resection in an Ecuadorian patient with Gorlin-Goltz syndrome by Andrea Villarreal-Juris in Journal of Clinical Case Reports Medical Images and Health Sciences 

ABSTRACT

Gorlin-Goltz syndrome is an inherited dominant autosomal disorder characterized by a predisposition to numerous cancers. The clinical-pathological findings of this syndrome are very diverse. The objective of this report is to present an Ecuadorian patient with Gorlin-Goltz syndrome who underwent surgical resection of basal cell carcinoma compatible lesions.

Conclusion: Gorlin-Goltz syndrome encompasses a variety of clinical signs and symptoms, including important oral manifestations and skin lesions that must be recognized to achieve an early specialty referral, thus reducing the risk of malignancy through a multidisciplinary treatment.

Keywords: Basal Cell Nevus Syndrome, Gorlin-Goltz syndrome, Carcinoma, Basal Cell

INTRODUCTION

Gorlin-Goltz (G-G) syndrome or nevoid basal cell carcinoma syndrome (NBCCS) is a dominant autosomal genetic disorder with high penetrance. Fifty percent of patients who suffer from it have a mutation in the long arm of chromosome 9q22.3 in the area of the PTCH gene (protein patched homolog) (1–3), a homologue of the Drosophila patched gene (PTC), which encodes a transmembrane receptor protein (4). This protein binds to a soluble factor of the hedgehog family (Hh), thus activating the Smo (smoothened) receptor, which unblocks the transcription of several growth factors. Therefore, the PTCH gene is an oncosuppressor that is part of the Sonic Hedgehog Homolog (Shh) signaling pathway and is crucial in embryonic development, cell division control, and tumor growth (5).

Its approximate prevalence is 1 in 57000 to 1 in 256000 and the ratio of males to females is 1:1 (6). Binkley and Johnson reported this syndrome for the first time in 1951 (7), then, in 1960, Gorlin and Goltz described the association between multiple basal cell carcinoma, odontogenic keratocysts (OKC) and bifid ribs, which account for the characteristic triad (8). In 1977, Rayner et al. added additional features, including calcification of the falx cerebri and palmar/plantar fossae (9).

According to the criteria of Kimonis et al., the diagnosis of G-G syndrome requires the coexistence of at least two major criteria or one major and two minor (10).

The characteristic that is usually diagnosed first is OKC, because it can be detected during the first decade of life and appears in almost 80% of G-G syndromes.

Other manifestations include palmar and plantar ulcers that appear as shallow pits, caused by partial or complete absence of the corneal layer, which can also appear along the sides of the hands and fingers and even on the tongue; spina bifida (10,11); medulloblastoma (can be an epiphenomenon of G-G, especially in children who are ≤5years-old) (12); cardiac tumors, including fibromas and ventricular histiocytomas, usually congenital (13); hypertelorism, congenital cataract, nystagmus, coloboma and strabismus (14); and ameloblastoma (extremely rare) (15,16).

Early diagnosis of G-G syndrome and its subsequent treatment are very important due to neoplasm susceptibility (2).

The case of a patient with a previous diagnosis of Gorlin-Goltz syndrome who presented multiple lesions compatible with basal cell carcinoma is presented below.

CASE REPORT

A 35-year-old male, living in Quito, Ecuador, without allergies; no history of tobacco or alcohol intake. His mother and his brother presented Gorlin-Goltz syndrome (G-G).

The patient presents hereditary and congenital G-G syndrome (multifocal basal cell carcinoma and maxillary keratocysts), whose manifestations began at the age of 22. He underwent surgery for bilateral keratocysts at the age of 25, and multiple biopsies of the upper left eyelid were taken since 2012. In August 2015, with a positive tumoral activity biopsy report, a wide resection involving 60% of the left upper eyelid plus flap reconstruction was performed.

Figure 1: Facial skin lesions and previous left maxillary keratocyst

Physical examination revealed multiple surgical scars on the left upper eyelid with tumoral activity on the eyelid margin, as well as on the outer third of the ipsilateral lower eyelid and on the right side.

Figure 2: Surgical scars with tumoral activity in the left and right eyelids.

In October, a wide resection of the left upper and lower eyelid was planned, plus reconstruction and transoperative study, which are performed without complications.

Figure 3 : Surgical planning

Figure 4 : Tumor resection involving the upper and lower eyelids with safety margins and surgical piece

Figure 5 : Confection of the left fronto-parietal flap

Figure 6: Immediate reconstruction results

Subsequently, the patient attended scheduled control, reporting the presence of a left superciliary nodular lesion. Physical examination revealed multiple lesions located in the left superciliary region, left helix, concha, and antihelix, in the inner corner of the left lower eyelid, in the left parieto-temporal and occipito-temporal regions, and other small bilateral genian lesions. There were no alterations in the flap. Left external campimetry was limited. It was decided to perform a facial bone and skull simple and contrasted tomography (CT) and laboratory tests.

Then, resection of the previously mentioned lesions and resection of the lower eyelid with transoperative study, shield-type incision and external canthoplasty of the lower left eyelid was planned. A plastic surgeon was included in the surgical team.

Figure 7: Shield-type incision

Altogether, 9 skin lesions located in the left superciliary, left frontal, interparietooccipital, posterior occipital, auricular, and left retroauricular regions were resected, which were positive for basal cell carcinoma.

In the subsequent control, the patient's campimetry showed improvement.

Figure 8 : Final result

DISCUSSION

Reports about Gorlin-Goltz syndrome are scarce in the literature (17). The rarity and phenotypic variability of this syndrome causes a delay in its diagnosis. Syndromicassociated keratocystic odontogenic tumors are often treated in the same way as nonsyndromic cases (18) and associated systemic signs can easily be missed due to lack of understanding of the syndrome. In addition, their characteristics vary globally, so doctors and even dentists must identify them in a timely manner, considering those that are more prevalent in their population or similar populations (19,20).

The pathogenesis of basal cell carcinoma (BCC) is thought to involve increased sensitivity to ultraviolet light and to involve ineffective mechanisms that repair UVinduced DNA damage. In any case, this theory is not accepted by all authors since these lesions can also appear in areas that have not been exposed to sunlight. Especially in children, patients with G-G syndrome who undergo radiotherapy for other cancers have shown to be at increased risk of radiation-induced BCC (21).

In 50% of patients with G-G syndrome, jaw keratocysts appear, characterized by a thin surrounding layer of epithelial cells, which tend to reappear locally after excision in 6 to 60% of cases, therefore, the indication for surgery should be carefully considered, also due to the possibility of intensive clinical and instrumental monitoring (22).

In recent years, new drugs have been developed to inhibit certain components of the sonic hedgehog signaling pathway. In 2013, the FDA approved vismodegib, the first small molecule to target this pathway (11). Although these agents seem promising options for patients with G-G syndrome, their efficacy is limited by adverse effects and the development of resistance (23). Logically, a more aggressive approach is necessary if basal cell carcinoma is suspected; subsequently, depending on the lesion site and the surgery type, a reconstruction can be performed, as in the case presented in this article (24,25).

CONCLUSION

Gorlin-Goltz syndrome encompasses a variety of clinical signs and symptoms, including important oral manifestations and skin lesions that must be recognized to achieve early referral to a specialty, thus reducing the risk of malignancy through multidisciplinary treatment.

Ethical responsibilities

In this case report, the informed consent of the patient was obtained. Its elaboration and all the inherent details were based on the Declaration of Helsinki.

Financing

Self-financed

Conflict of interests

The authors declare the non-existence of conflicts of interest.

For more information: https://jmedcasereportsimages.org/about-us/

For more submission : https://jmedcasereportsimages.org/

[sparkgroup11]

Odontogenic Tumor Market Share,Size, Type, Application and Forecast...

[michaeljacksonlighterpost]

I need medical help ASAP

I have an aggressive tumor-like cyst (Odontogenic keratocyst) in my jaw that needs to be removed as soon as possible. I would use the money to help cover the medical expenses. The removal and recovery procedures will cost over 7,000 dollars.

Any bone that has made contact with the growth must be removed; I will already be losing 4 teeth because they came into contact with the cyst.

Likewise, I want to have this surgery in the next 6 months or, preferably, less so the growth has minimal time to expand (and potentially infect more jaw bone and teeth).

It's difficult to save money for the procedure because I'm only 20 and have been living alone since age 17. Any money I make goes towards living expenses.

I also don't have an extensive credit history due to my age, and likewise am ineligible for most loans. I've genuinely tried everything; e-begging is my last resort.

REBLOG & BOOST THIS PLEASE, I NEED HELP

Any amount helps or simply sharing so others may see.

I don't know what else to do, and I'm so scared of what's to come if I can't save up money in a timely manner.

Update: October 2023, help would still be appreciated. I'm still financially unstable.

[sootyships]

me researching ways to make the mers ~weird~

i kinda wanna indicate the last common ancestor of them and humans was... a long-ass fucking time ago. similarities come from convergent evolution, maybe specifically predation

-might have a parietal eye

-might have gular/thoracic and post/paracloacal scent gland(s)... cloacal glands used in marking territory

-fish nostrils = nares

-nose==snout

-two dorsal fins with separate bases

-lateral line organ

- 5 year gestation?

- 7 fins – two dorsal fins, two pectoral fins, two pelvic fins and one caudal fin

- spiracle-ear?

- operculum? (gill cover bone that helps draw in water)

- ears: basilar papilla?

- gills+spiracles need to remain moist

- cosmoid/(elasmoid)/ganoid scales

- good sense of smell

- lackluster amphibian eyesight

- metamorphosis

- sequential hermaphrodites?

- palatal teeth~~~

- anamniotes

- fewer ear bones than humans/synapsids, columella or maybe a stapes? more jaw bones

- maybe should have an ear drum in the otic notch? -> no spiracle (bird/crocodile ears) or could breathe air thru the spiracle

- Both sexes have a cloaca, a single chamber and outlet at the base of the tail into which the intestinal, urinary and genital tracts open.[32] It houses the penis in males and the clitoris in females.[36] The crocodilian penis is permanently erect and relies on cloacal muscles for eversion and elastic ligaments and a tendon for recoil.

- teeth visible when mouth closed like crocodilians?

- scleral cartilage

- nictating membranes!

The head or skull includes the skull roof (a set of bones covering the brain, eyes and nostrils), the snout (from the eye to the forward-most point of the upper jaw), the operculum or gill cover (absent in sharks and jawless fish), and the cheek, which extends from the eye to the preopercle. The operculum and preopercle may or may not have spines. In sharks and some primitive bony fish the spiracle, a small extra gill opening, is found behind each eye. 

Juvenile P. mokelembembe have external gills that resemble those of young amphibians. These gills are large and have branching, featherlike architecture to maximize surface area for oxygen exchange to compensate for the young fish's underdeveloped respiratory system. As the fish age and their lungs develop, they lose these external gill structures and take on the gill structure of a typical fish.

primitive shape of its jawbones are more akin to that of a salamander's than a fish.[7]

The mouth is large and appears to grin when closed. The dentary, premaxilla, and maxilla each carry one row of large, slightly recurved teeth.[4] There are multiple rows of smaller teeth, found between the rows of large teeth, on the prearticular and coronoids in the lower jaw and on the bones forming the roof of the mouth.

Being shallow-water fishes, the elpistostegalians evolved many of the basic adaptions that later allowed the tetrapods to become terrestrial animals. The most important ones were the shift of main propulsion apparatus from the tail fin to the pectoral and pelvic fins, and a shift to reliance on lungs rather than gills as the main means of obtaining oxygen.[12] Both of these appear to be a direct result of moving to an inland freshwater mode of living.[13]

Crocodilians are homodonts, meaning each of their teeth are all of the same type (they do not possess different tooth types, such as canines and molars) and polyphyodonts are able to replace each of their approximately 80 teeth up to 50 times in their 35 to 75-year lifespan.[51] They are the only non-mammalian vertebrates with tooth sockets.[52] Next to each full-grown tooth there is a small replacement tooth and an odontogenic stem cell in the dental lamina in standby, which can be activated when required.[53] Tooth replacement slows significantly and eventually stops as the animal grows old.[

It has a cleithrum, a bone in the pectoral girdle that extends from the scapula. The cleithrum once attached to the skull in lobe-finned fish, the ancestors of tetrapods, but detached to allow the neck to move freely.

[unsoundedcomic]

***whispers*** Coppers are just pymarically controlled, holistically cancerous bodies... gross. Can't wait for the odontogenic tumors. Also, I didn't recall Waekhes being a thing! They sound neat.

It's Tainish, so I wouldn't pluralize it like that. It literally means "burnt," and is slurrish. But yeah, if you read the extra story in the third print volume, there's a waekhe character in it.

[supriyapuram]

Odontogenic Tumors Important Question And Answers

[uday-123]

https://www.verifiedmarketreports.com/product/odontogenic-tumor-market/

[vasanthasworld]

Odontogenic Tumors Question and answers

[christophercbabcock]

Dentoalveolar Surgery and Cysts in the Jaw and Surrounding Tissue

Dentoalveolar encompasses bone and soft tissues surrounding and supporting the teeth, including the jawbone and the gum. Surgery in this region becomes necessary in gum recession, impacted teeth, tumors, and cysts. In the latter arena, fluid-filled sacs may form in the jaw. Often related to infection, such as advanced periodontal disease, the cysts may also have roots in developmental abnormalities or genetic disposition.

There are four main types of jaw cysts, with radicular cysts related to an infection in the root canal or tooth pulp. Dentigerous cysts form around the crown of a tooth that remains unerupted. A rare occurrence, aneurysmal bone cysts result in bone pain and expansion. Finally, odontogenic keratocysts in the lower jaw are linked to genetic disorders.

Cysts often cause pain as they expand and place pressure on other tissues. They may also cause tooth alignment or bite changes if pressure is placed on the teeth. There may be a visible lump or bump on the jawbone or gums. In some instances, the cyst becomes infected, which may result in pus drainage and swelling.

Removing such cysts involves an incision in the gum tissue, with the cyst and the affected surrounding tissue eliminated. Sometimes, patients require bone grafts to fill in and provide structural support to the space vacated by the cyst.

[uncensoredalexander]

I’m not too fond of taking pills - I don’t necessarily think most people are, but I guess the motion of swallowing something whole may appeal to someone looking for a reason to heal a pain that you can’t see.

Amoxicillin is an antibiotic medication that belongs to the penicillin family. It’s used to treat middle ear infection, strep throat, pneumonia, skin infections, odontogenic infections, and urinary tract infection. For the past few days, I’ve experienced hell in the form of a shooting knife grazing underneath my skin; I feel it in my ear, pushing from the inside out. I can’t listen to music in the left ear, so I listen to ramblings with the right - how funny that pain can you force you to amend the little things in your life. In reality, my ear is not the problem but everything around it culminating in a sporadic, agonising pain.

Everything in my life is painful but me; my brain, my skin doesn’t feel right, the fact that tomorrow is the first day of the last “term 4,” the fact that this time next year I’ll be throwing up from anxiety, the fact that I’m not sure how to feel about growing up, the fact that time is finite, the fact that we are dying, the fact that I’m scared of dying, the fact that I know this repetition came from a book that I couldn’t get through, the fact that my books are dying, the fact that I’m just scared.

[anuragbhargava]

Cysts and Tumors of the Oral Cavity: Diagnosis and Treatment Demystified by Oral Surgeon in Indore

Your oral health is not just about your teeth and gums; it also involves understanding and addressing various conditions that can affect your mouth. Cysts and tumors of the oral cavity, although daunting terms are essential to comprehend. This blog aims to demystify these conditions, explaining their diagnosis and treatment in simple terms.

Understanding Cysts and Tumors

Firstly, let's break down these terms. Cysts are fluid-filled sacs while tumors are abnormal growths. In the oral cavity, these formations can occur in various forms and sizes. Some are benign (non-cancerous), while others might be malignant (cancerous). The critical aspect is early detection, making regular dental check-ups crucial.

Diagnosis: The Importance of Early Detection

Regular dental check-ups play a pivotal role in the early detection of oral cysts and tumors. Dentists often use imaging techniques such as X-rays, CT scans, or MRIs to get a detailed view. Biopsies, where a small sample of the tissue is taken and examined under a microscope, are essential for confirming the diagnosis.

Types of Oral Cysts and Tumors

Oral cysts and tumors can vary widely. Cysts like odontogenic cysts develop from tissues involved in tooth development. Tumors can be either benign (like fibromas) or malignant (like oral carcinomas). Each type requires a specific approach to diagnosis and treatment.

Treatment Approaches

Treatment options depend on the type, size, and location of the cyst or tumor, as well as whether it is benign or malignant. Small, benign cysts might need no more than regular monitoring. Larger or cancerous growths might require surgery, often followed by chemotherapy or radiation therapy. The treatment plan is personalized for each patient, focusing on both eradication and preservation of oral function and aesthetics.

The Role of Oral and Maxillofacial Surgeons in Indore

Oral and maxillofacial surgeons in Indore are specialists in diagnosing and treating these conditions. Their expertise ensures that the cyst or tumor is thoroughly removed while preserving as much healthy tissue as possible. These professionals also play a crucial role in reconstructive surgery if needed, helping patients regain both their health and confidence.

Emotional Support and Aftercare

Dealing with an oral cyst or tumor can be emotionally challenging. It’s essential for patients to have a strong support system, including family, friends, and healthcare professionals. Post-treatment, regular follow-ups are crucial to monitor recovery and catch any potential issues early.

Conclusion: Empowerment through Knowledge

In conclusion, understanding oral cysts and tumors empowers you to take charge of your oral health. Regular dental check-ups, awareness of symptoms, and prompt medical consultation are your best allies in this journey. Remember, early detection and proper treatment can make a significant difference. So, prioritize your oral health, and don’t hesitate to seek professional advice if you have any concerns. Your smile deserves the best care possible. 

Original Source: https://dranuragbhargavasurgeon.blogspot.com/2023/10/cysts-and-tumors-of-oral-cavity.html

[sparkgroup11]

Odontogenic Tumor Market Size,Share, Trend, Challenges, Segmentation and Forecast To 2027

[surakshadentalguntur]

Surakha Dental Clinic: Your Destination for Comprehensive Oral Health Care in Guntur

Welcome to Surakha Dental Clinic, your premier destination for top-notch oral health care services in Guntur. Our team of highly skilled and experienced oral surgeons, led by Dr. Praveen Kumar Gali and Dr. Divya Sri Godavarthy, is dedicated to providing the highest quality of care to our patients. Today, we'll delve into the intricate world of oral surgery, specifically focusing on minor oral surgery, oral cyst removal, and impacted tooth extraction. In addition, we'll explore the specialized procedure of deeply seated mandibular canine with dentigerous cyst removal.

## Minor Oral Surgery: A Precise and Painless Procedure

Minor oral surgery encompasses a range of surgical procedures performed within the oral cavity. These procedures are typically minimally invasive and are designed to address a variety of issues, including tooth extractions, soft tissue biopsies, and cyst removal. At Surakha Dental Clinic, our team excels in providing minor oral surgery services, ensuring that you receive the best care possible.

One of the most common minor oral surgery procedures is tooth extraction, particularly when dealing with impacted teeth. An impacted tooth occurs when it fails to erupt fully through the gum line due to lack of space or unfavorable positioning. This condition can lead to discomfort, pain, and dental complications. Dr. Praveen Kumar Gali and Dr. Divya Sri Godavarthy are experts in performing painless and efficient impacted tooth extractions.

## Oral Cyst Removal: Restoring Oral Health Safely

Oral cysts are fluid-filled sacs that can develop within the oral cavity. They may manifest as soft, painless swellings, but they have the potential to cause serious complications if left untreated. The removal of oral cysts is crucial to prevent further issues and maintain your oral health.

At Surakha Dental Clinic, our surgeons are highly proficient in the removal of oral cysts. Whether you have a radicular cyst, dentigerous cyst, or any other type of cyst affecting your oral health, our team will diagnose and provide a tailored treatment plan for your specific condition.

## Dentigerous Cyst Removal: Precision and Expertise

A dentigerous cyst is a type of odontogenic cyst that forms around the crown of an impacted tooth, most commonly involving the mandibular canine. This condition can be challenging to address due to the cyst's proximity to the tooth and its potential impact on adjacent structures. Dr. Praveen Kumar Gali and Dr. Divya Sri Godavarthy are renowned for their expertise in deeply seated mandibular canine with dentigerous cyst removal.

The procedure involves the following steps:

1. **Diagnostic Imaging:** Precise diagnosis is crucial. We use advanced imaging techniques such as CBCT scans to visualize the cyst and its relation to surrounding structures.

2. **Anesthesia:** Before the surgery, you will receive local anesthesia to ensure you feel no pain during the procedure.

3. **Incision:** A small incision is made in the oral tissue to access the cyst.

4. **Cyst Removal:** The cyst is carefully removed, taking great care not to damage the impacted tooth or adjacent structures.

5. **Tooth Extraction (if necessary):** In some cases, the impacted tooth may need to be extracted to ensure complete removal of the cyst.

6. **Closure:** The incision is sutured closed with dissolvable stitches.

7. **Post-operative Care:** After the procedure, you will be provided with detailed instructions for post-operative care to promote healing and prevent infection.

## Why Choose Surakha Dental Clinic for Your Oral Surgery Needs?

- **Best in Guntur:** Our clinic is renowned as the best in Guntur for oral surgery, thanks to the expertise of Dr. Praveen Kumar Gali and Dr. Divya Sri Godavarthy.

- **Single Day Procedure:** We understand the value of your time, and many of our procedures, including minor oral surgeries and cyst removals, can often be completed in a single day.

- **Painless Surgery:** Your comfort is our priority. We utilize advanced anesthesia techniques and minimally invasive procedures to ensure you experience minimal discomfort during and after surgery.

- **Comprehensive Care:** Surakha Dental Clinic offers a full spectrum of oral health services, from routine check-ups to complex surgical procedures, ensuring all your dental needs are met under one roof.

- **Cutting-edge Technology:** We stay at the forefront of dental technology, using state-of-the-art equipment and diagnostic tools to provide the highest standard of care.

For all your oral surgery needs, trust Surakha Dental Clinic to deliver excellence in dental care. Schedule your consultation today and experience the difference for yourself.

## #Dental #Guntur #Oral #Mouth #Jaw #Cyst #Removal #Surgery #MinorOralSurgery #BestinGuntur #SingleDayProcedure #PainlessSurgery #BestJawSurgeryGuntur #DentigerousCyst #OralHealth #ExpertSurgeons #OralCare #DentalClinic #HealthySmile #SurgicalExcellence #PatientCare #ImpactedTooth #OralCystRemoval #OralSurgeryExperts #DentalTechnology #PreciseTreatment #OralHealthMatters #DentalExcellence #OralHealthCare #TopDentists #GunturHealthcare #DentalExperts #CaringSurgeons #PainlessDentistry #QualityOralCare #ComprehensiveTreatment #GunturHealth #SpecializedDentistry #GentleOralSurgery #ToothExtraction #DentalProcedure #SmileRestoration #OralWellness #CompleteOralCare #OralSurgeons #HealthyTeeth #OralRecovery #OralRehabilitation #OralHealthFirst #PatientComfort #ExperiencedDentists #AdvancedDentalCare #GunturDentalClinic #ExpertDentalTeam #OralHealthJourney #OralHealthSpecialists #AdvancedSurgicalTechniques #GunturSmile #OralHealthGoals

[lupine-publishers-ipdoaj]

Surgical Management of Massive Dentigerous Cyst in Mixed Dention- A Case Report

Abstract

A dentigerous cyst is an odontogenic cyst thought to be of developmental origin associated with the crown of an unerupted tooth. Such cysts remain initially completely asymptomatic unless when infected. It is detected clinically when becomes large and associated with swelling of the face. The purpose of this case report was to describe the diagnosis and management of a dentigerous cyst in an 8-year-old boy. The chosen treatment was cyst enucleation and tooth extraction.

Keywords: Dentigerous cyst; enucleation; Mixed dentition

Abbreviation: DC: Dentigerous Cyst

Read More About This Article Please Click on Below Link: https://lupinepublishers.com/pediatric-dentistry-journal/fulltext/surgical-management-of-massive-dentigerous-cyst-in-mixed-dention-a-case-report.ID.000260.php

Read More About Lupine Publishers Google Scholar Articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=h1QvhsYAAAAJ&citation_for_view=h1QvhsYAAAAJ:rO6llkc54NcC

[lupine-publishers-sjo]

Orbital Ameloblastic Carcinoma – Unusual Presentation in A Non-Odontogenic Location

Abstract

Ameloblastic carcinoma has been described as an ameloblastoma in which there is histological evidence of carcinoma in a primary or recurrent ameloblastoma. The frequency of the lesion is estimated to be less than 1% of all ameloblastomas occurring in the mandible and maxilla.1 We present a case of a 30-year-old woman who presented with painless swelling of left upper face and recurrent upper respiratory tract infections. She was evaluated with CECT, MRI and PET-CT which showed 3.6 x 3.5 x 3.3 cm mass arising from the inferomedial wall of left orbit with sunburst periosteal reaction and cloudy osteoid matrix which was thought to be an osteosarcoma. She underwent a transorbital and trans nasal endoscopic wide local excision of the lesion which was then diagnosed as ameloblastic carcinoma on histopathology. Imaging features and pathological findings of the tumor along with novel treatment strategies and differential diagnosis are discussed in this case report.

Keywords: MRI; orbital tumor; ameloblastic carcinoma; osteosarcoma; CECT; PET

Abbreviations: 18F-FDG-PET: 18F-fluorodeoxyglucose–Positron Emission Tomography; CECT: Contrast Enhanced Computed Tomography; FLAIR: Fluid Attenuated Inversion Recovery; MRI: Magnetic Resonance Imaging; WHO: World Health Organization

Read More About This Article Click on Below Link: https://lupinepublishers.com/otolaryngology-journal/fulltext/orbital-ameloblastic-carcinoma-unusual-presentation-in-a-non-odontogenic-location.ID.000260.php Read More about Lupine Publishers Google Scholar Articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=dMOUw-wAAAAJ&cstart=100&pagesize=100&citation_for_view=dMOUw-wAAAAJ:v_xunPV0uK0C