#radioiodine

[jimmyisawkward]

Do not the cat.

[pseudophan]

@ thyroid cancer anon I also had the same in 2019 then I had radioiodine treatment and woke up from a nap after it to BIG coming out so … maybe there’s something to look forward to?

are you saying dnp are gonna do something crazy when anon goes in for cancer treatment is this how we measure the likelihood of dnp insanity now

[luninosity]

Hi, internet family!

This is not a real asking-for-money type post, I promise! More a sort of...if you like the things I write, and you have been thinking about buying a thing I write, now would be a really lovely time?

So this small monster (in the pic above) has been diagnosed with *aggressive* hyperthyroidism - like, it basically went from 0-60 super-fast; her T4 value should be around 2.5-3.0 and suddenly it's at 11 (on a scale of about 20) - and the two options are either 1) meds twice a day for the rest of her life, or 2) radioiodine therapy, one time, 95% effective. She went from weighing around 9 pounds to 7.1 in just a couple months, which is a lot when you're a little kitty!

Either way it's going to be expensive, but because she's healthy otherwise, and we could hopefully have her for many more years (she's 13, but, again, otherwise totally healthy; kidneys are fine, heart is fine, my family has had several cats that lived to be ~20), so we're going to do the one-time radioiodine therapy.

Which starts at, er, $2,500. Might be more, depending on how long they need to keep her in the clinic until she, er, passes the radioactive isotope (yep). But we did the math and that's actually cheaper than, say, another 5+ years of her medication 2x daily.

So, again, not at all a sort of "send us money" post! - we *can* afford it, it just...is a big expense we had not budgeted for, which we will essentially have to pay mostly at once (we did the deposit already, the rest is due in early June after her appointment).

And there are many many other big important things happening in the world right now! over here we have been donating to World Central Kitchen! - so, again, no worries; we are okay and we shall be okay! It's just a surprise!large amount of money, as it were.

But if you would like to buy a thing I write, if you like LGBTQ romance and fantasy and history and bad puns about bread, and you've been thinking about maybe trying a story of mine, we would certainly appreciate it right around now, as it were?

Here's me at JMS Books

and me at Amazon

(also available at Barnes & Noble, Kobo, etc)

[proteesiukkonen]

Took my other cat to the vet today to receive radioiodine therapy for hyperthyroidism and she has to stay at the clinic until Saturday for radiation security.

It's awful cause coming home without the cat and the carrier or any of the bags I took there (food and safety blanket) is so out of the ordinary for a vet visit, I keep getting these split-second jolts of unfiltered horror like oh shit I forgot the bag OH SHIT I FORGOT THE CARRIER OH CHRIST THE CAT-

[wtfuckevenknows]

Well guess whose tumor isn’t so forward after all and who needs radioiodine therapy after all 🙃

[hyenaswine]

bubo has his 3-month post-radioiodine vet appointment tomorrow. mostly i'm interested to see if he's put any weight on. i think he has. he looks really healthy to me.

[i-raised-you-danker-than-this]

hey guys this guy’s cat needs a 3k surgery and i’m pretty sure the deadline is tonight. he’s super close to his goal if anyone is able to help

[patchworkboy]

Acute radiation syndrome (ARS), also known as radiation sickness or radiation poisoning, is a collection of health effects that are caused by being exposed to high amounts of ionizing radiation in a short period of time.[1] Symptoms can start within an hour of exposure, and can last for several months.[1][3][5] Early symptoms are usually nausea, vomiting and loss of appetite.[1] In the following hours or weeks, initial symptoms may appear to improve, before the development of additional symptoms, after which either recovery or death follow.

ARS involves a total dose of greater than 0.7 Gy (70 rad), that generally occurs from a source outside the body, delivered within a few minutes. Sources of such radiation can occur accidentally or intentionally. They may involve nuclear reactors, cyclotrons, certain devices used in cancer therapy, nuclear weapons, or radiological weapons.[4] It is generally divided into three types: bone marrow, gastrointestinal, and neurovascular syndrome, with bone marrow syndrome occurring at 0.7 to 10 Gy, and neurovascular syndrome occurring at doses that exceed 50 Gy.[1][3] The cells that are most affected are generally those that are rapidly dividing.[3] At high doses, this causes DNA damage that may be irreparable.[4] Diagnosis is based on a history of exposure and symptoms.[4] Repeated complete blood counts (CBCs) can indicate the severity of exposure.[1]

Treatment of ARS is generally supportive care. This may include blood transfusions, antibiotics, colony-stimulating factors, or stem cell transplant.[3] Radioactive material remaining on the skin or in the stomach should be removed. If radioiodine was inhaled or ingested, potassium iodide is recommended. Complications such as leukemia and other cancers among those who survive are managed as usual. Short term outcomes depend on the dose exposure.[4]

ARS is generally rare.[3] A single event can affect a large number of people,[7] as happened in the atomic bombings of Hiroshima and Nagasaki and the Chernobyl nuclear power plant disaster.[1] ARS differs from chronic radiation syndrome, which occurs following prolonged exposures to relatively low doses of radiation.[8][9]

Signs and symptoms[edit]

See also: Effects of nuclear explosions on human healthRadiation sickness

Classically, ARS is divided into three main presentations: hematopoietic, gastrointestinal, and neurovascular. These syndromes may be preceded by a prodrome.[3] The speed of symptom onset is related to radiation exposure, with greater doses resulting in a shorter delay in symptom onset.[3] These presentations presume whole-body exposure, and many of them are markers that are invalid if the entire body has not been exposed. Each syndrome requires that the tissue showing the syndrome itself be exposed (e.g., gastrointestinal syndrome is not seen if the stomach and intestines are not exposed to radiation). Some areas affected are:

Hematopoietic. This syndrome is marked by a drop in the number of blood cells, called aplastic anemia. This may result in infections, due to a low number of white blood cells, bleeding, due to a lack of platelets, and anemia, due to too few red blood cells in circulation.[3] These changes can be detected by blood tests after receiving a whole-body acute dose as low as 0.25 grays (25 rad), though they might never be felt by the patient if the dose is below 1 gray (100 rad). Conventional trauma and burns resulting from a bomb blast are complicated by the poor wound healing caused by hematopoietic syndrome, increasing mortality.

Gastrointestinal. This syndrome often follows absorbed doses of 6–30 grays (600–3,000 rad).[3] The signs and symptoms of this form of radiation injury include nausea, vomiting, loss of appetite, and abdominal pain.[10] Vomiting in this time-frame is a marker for whole body exposures that are in the fatal range above 4 grays (400 rad). Without exotic treatment such as bone marrow transplant, death with this dose is common,[3] due generally more to infection than gastrointestinal dysfunction.

Neurovascular. This syndrome typically occurs at absorbed doses greater than 30 grays (3,000 rad), though it may occur at doses as low as 10 grays (1,000 rad).[3] It presents with neurological symptoms such as dizziness, headache, or decreased level of consciousness, occurring within minutes to a few hours, with an absence of vomiting, and is almost always fatal, even with aggressive intensive care.[3]

Early symptoms of ARS typically include nausea, vomiting, headaches, fatigue, fever, and a short period of skin reddening.[3] These symptoms may occur at radiation doses as low as 0.35 grays (35 rad). These symptoms are common to many illnesses, and may not, by themselves, indicate acute radiation sickness.[3]

Dose effects[edit]

PhaseSymptomWhole-body absorbed dose (Gy)1–2 Gy2–6 Gy6–8 Gy8–30 Gy> 30 GyImmediateNausea and vomiting5–50%50–100%75–100%90–100%100%Time of onset2–6 h1–2 h10–60 min< 10 minMinutesDuration< 24 h24–48 h< 48 h< 48 h— (patients die in < 48 h)DiarrheaNoneNone to mild (< 10%)Heavy (> 10%)Heavy (> 95%)Heavy (100%)Time of onset—3–8 h1–3 h< 1 h< 1 hHeadacheSlightMild to moderate (50%)Moderate (80%)Severe (80–90%)Severe (100%)Time of onset—4–24 h3–4 h1–2 h< 1 hFeverNoneModerate increase (10–100%)Moderate to severe (100%)Severe (100%)Severe (100%)Time of onset—1–3 h< 1 h< 1 h< 1 hCNS functionNo impairmentCognitive impairment 6–20 hCognitive impairment > 24 hRapid incapacitationSeizures, tremor, ataxia, lethargyLatent period28–31 days7–28 days< 7 daysNoneNoneIllnessMild to moderate Leukopenia Fatigue WeaknessModerate to severe Leukopenia Purpura Hemorrhage Infections Alopecia after 3 GySevere leukopenia High fever Diarrhea Vomiting Dizziness and disorientation Hypotension Electrolyte disturbanceNausea Vomiting Severe diarrhea High fever Electrolyte disturbance Shock— (patients die in < 48h)MortalityWithout care0–5%5–95%95–100%100%100%With care0–5%5–50%50–100%99–100%100%Death6–8 weeks4–6 weeks2–4 weeks2 days – 2 weeks1–2 daysTable source[11]

A similar table and description of symptoms (given in rems, where 100 rem = 1 Sv), derived from data from the effects on humans subjected to the atomic bombings of Hiroshima and Nagasaki, the indigenous peoples of the Marshall Islands subjected to the Castle Bravo thermonuclear bomb, animal studies and lab experiment accidents, have been compiled by the U.S. Department of Defense.[12]

A person who was less than 1 mile (1.6 km) from the atomic bomb Little Boy's hypocenter at Hiroshima, Japan, was found to absorb about 9.46 grays (Gy) of ionizing radiation.[13][14][15][16]

The doses at the hypocenters of the Hiroshima and Nagasaki atomic bombings were 240 and 290 Gy, respectively.[17]

Skin changes[edit]

Main article: Radiation burnHarry K. Daghlian's hand 9 days after he had manually stopped a prompt critical fission reaction during an accident with what later obtained the nickname the demon core. He received a dose of 5.1 Sv,[18] or 3.1 Gy.[19] He died 16 days after this photo was taken.

Cutaneous radiation syndrome (CRS) refers to the skin symptoms of radiation exposure.[1] Within a few hours after irradiation, a transient and inconsistent redness (associated with itching) can occur. Then, a latent phase may occur and last from a few days up to several weeks, when intense reddening, blistering, and ulceration of the irradiated site is visible. In most cases, healing occurs by regenerative means; however, very large skin doses can cause permanent hair loss, damaged sebaceous and sweat glands, atrophy, fibrosis (mostly keloids), decreased or increased skin pigmentation, and ulceration or necrosis of the exposed tissue.[1] As seen at Chernobyl, when skin is irradiated with high energy beta particles, moist desquamation (peeling of skin) and similar early effects can heal, only to be followed by the collapse of the dermal vascular system after two months, resulting in the loss of the full thickness of the exposed skin.[20] Another example of skin loss caused by high-level exposure of radiation is during the 1999 Tokaimura nuclear accident, where technician Hisashi Ouchi had lost a majority of his skin due to the high amounts of radiation he absorbed during the irradiation. This effect had been demonstrated previously with pig skin using high energy beta sources at the Churchill Hospital Research Institute, in Oxford.[21]

Cause[edit]

Both dose and dose rate contribute to the severity of acute radiation syndrome. The effects of dose fractionation or rest periods before repeated exposure also shift the LD50 dose upwards.Comparison of Radiation Doses – includes the amount detected on the trip from Earth to Mars by the RAD on the MSL (2011–2013).[22][23][24][25]

ARS is caused by exposure to a large dose of ionizing radiation (> ~0.1 Gy) over a short period of time (> ~0.1 Gy/h). Alpha and beta radiation have low penetrating power and are unlikely to affect vital internal organs from outside the body. Any type of ionizing radiation can cause burns, but alpha and beta radiation can only do so if radioactive contamination or nuclear fallout is deposited on the individual's skin or clothing. Gamma and neutron radiation can travel much greater distances and penetrate the body easily, so whole-body irradiation generally causes ARS before skin effects are evident. Local gamma irradiation can cause skin effects without any sickness. In the early twentieth century, radiographers would commonly calibrate their machines by irradiating their own hands and measuring the time to onset of erythema.[26]

Accidental[edit]

Main article: Nuclear and radiation accidents and incidents

Accidental exposure may be the result of a criticality or radiotherapy accident. There have been numerous criticality accidents dating back to atomic testing during World War II, while computer-controlled radiation therapy machines such as Therac-25 played a major part in radiotherapy accidents. The latter of the two is caused by the failure of equipment software used to monitor the radiational dose given. Human error has played a large part in accidental exposure incidents, including some of the criticality accidents, and larger scale events such as the Chernobyl disaster. Other events have to do with orphan sources, in which radioactive material is unknowingly kept, sold, or stolen. The Goiânia accident is an example, where a forgotten radioactive source was taken from a hospital, resulting in the deaths of 4 people from ARS.[27] Theft and attempted theft of radioactive material by clueless thieves has also led to lethal exposure in at least one incident.[28]

Exposure may also come from routine spaceflight and solar flares that result in radiation effects on earth in the form of solar storms. During spaceflight, astronauts are exposed to both galactic cosmic radiation (GCR) and solar particle event (SPE) radiation. The exposure particularly occurs during flights beyond low Earth orbit (LEO). Evidence indicates past SPE radiation levels that would have been lethal for unprotected astronauts.[29] GCR levels that might lead to acute radiation poisoning are less well understood.[30] The latter cause is rarer, with an event possibly occurring during the solar storm of 1859.

when i catch you i swear。

[fattlestacks]

I may open commissions soon since my work list is currently empty and I still need to make some funds for Nermal's ongoing treatment (he's home from radioiodine therapy and seems to be doing okay, but his bill was like $1400 oof...)

If you've been wanting a commission, keep your eyes peeled. I'm also trying to gauge interest so feel free to leave a comment if you plan to try to snag one, thanks!

[unicornery]

the full story of how I got Reggie:

Calypso died in early Nov of 2019. By the end of Jan 2020, I was starting to feel ready for a new cat or cats.

I made the post on my FB about looking for a “used orange cat” and my friend Angie who works at a vet hospital on the south side saw it. Not four days later, I got a message from her about an orange boy they had at her office who was looking for a home. She explained that they had a deal with the city of Carlisle, just south of Des Moines, to help rehome strays their PD picked up.

Angie sent a few pics of the cat and said he was very friendly, and healthy apart from needing a couple teeth pulled. I made a trip down to the south side to meet him. I had used this particular vet hospital before, when Trinity needed the radioiodine treatment for her hyperthyroid.

When I met the cat, he was such a love, let me hold him, not shy at all. I was honestly convinced that he belonged to someone, and that I shouldn’t get my hopes up. He was in the middle of a seven-day waiting period to be claimed. When I got home, I even searched on some Iowa missing pet sites to see if someone had reported him lost.

A few days later, I got another message from Angie. As no one had come to claim him, the sweet orange cat could be mine. I made arrangements to pick him up after work on the 4th. [edit--the caucuses were on the 3rd and I had preemptively taken PTO for the day after, and it came in handy] I bought a few supplies so he could have his own bed that didn’t smell like the old cats, and some wet food since he had that broken tooth. Before I left the clinic, I made an appointment to bring him back for the tooth extraction in a couple days.

I took the cat home and set up a little area for him in the same upstairs bedroom where Trinity had rehabbed after an operation. He had a litterbox, food dish, water bowl, a cat bed, and the pineapple house. I played with him and let him settle in. He enjoyed going behind the curtain so I put the cat bed behind it to give him a place to sit.

In my original FB post I had made a joke about wanting a cat in “size XL,” as Calypso had been a pretty big cat. But as I looked at this new boy, I thought about how small he was, or rather medium-sized. I remembered a gag on the Birthday Boys TV show about variety show acts named “Big Reginald” “Little Reginald” and “Medium Reginald.” So I gave my medium-sized cat a medium name, “Medium Reginald” or “Reggie” for short. I did a cursory google for orange+cat+Reggie and was delighted to learn that one of the animal actors who played the orange in Captain Marvel was named Reggie.

The timing, of course, ended up being particularly auspicious, as before long I was at home all day, every day, giving us plenty of time to bond together. He recovered well from the dental surgery, and he was doing well on the wet food, so I decided to keep him on that since I was always home to give him breakfast and dinner. I slept upstairs with him for the first couple weeks, then slowly started introducing him to the rest of the house.

We’re coming up on three years together and I’m so glad it worked out the way it did. Sometimes I feel his little toe beans and think about how rough they were when I first brought him home. He was not meant for the streets; he was meant to be my little son and friend ❤️❤️❤️

[magdasabs]

German "Bild Zeitung," wrote, that Berger is finish with her treatment and that the radioiodine therapy was enough. Idk if this believable or not. But it's nice to see her back in training.

I wouldn't trust bild but it's possible I guess

[sqinsights]

Navigating the Thyroid Maze: A Peek into the World of Thyroid Gland Disorders Treatment

Welcome, curious minds, to the fascinating realm of thyroid gland disorders treatment. No capes, no superheroes, but a booming market poised to hit the $3.14 billion mark by 2031. Hold on to your hats; we’re about to dive into a world where thyroid troubles are met with innovation, a touch of sarcasm, and maybe a pinch of levothyroxine.

The Global Thyroid Scene: A Growth Odyssey

In the vast landscape of healthcare, the thyroid gland treatment market stands tall at a whopping $2.37 billion in 2022. Why the surge? Well, it seems our thyroids are getting chatty and causing a ruckus globally. Blame it on the expanding aging populations, better medical tech, or just the thyroid being the rebellious teenager of our endocrine system.

Treatment Tango: New Moves and Partnerships

Enter stage left: customized medicine techniques and novel drugs strutting their stuff. North America and Europe take the lead in this dance, with their higher rates of thyroid troubles and an iron grip on the healthcare kingdom. But wait, there’s a plot twist! Emerging economies in Latin America and Asia-Pacific are waltzing in, with improved healthcare infrastructure and growing awareness.

Telemedicine: The Thyroid Whisperer

In the ever-evolving healthcare landscape, telemedicine takes the spotlight. Imagine sitting in your PJs, consulting about your thyroid with a doctor miles away. Telehealth services are all the rage for endocrinology consultations, medication management, and those oh-so-fun routine check-ups. It’s like having a medical genie in your smartphone — magic, right?

Market Snapshot: The Thyroid Soap Opera

Fasten your seatbelts; we’re about to witness the grand spectacle of market snapshots. Thyroidectomy takes center stage as the largest segment, while radioiodine therapy steals the show as the fastest-growing sensation. With a 3.17% CAGR, the global thyroid gland disorders treatment market is indeed giving us a gripping saga.

For More Information: https://www.skyquestt.com/report/thyroid-gland-disorders-treatment-market

The Players in This Health Drama

Hold on, we’ve got stars in this show — AbbVie Inc., Pfizer Inc., and more. These pharmaceutical juggernauts are engaged in a fierce competition, racing to develop groundbreaking medications and formulations. It’s like the Oscars, but for thyroid treatment. Cue the red carpet!

Regional Rollercoaster: From North America to APAC

North America, particularly the US, takes the crown, thanks to widespread thyroid troubles and a well-oiled healthcare system. But wait, there’s an underdog climbing the ladder — the Asia-Pacific (APAC) region. China and India are in the spotlight, dancing to the tune of changing lifestyles and rising healthcare costs. Who knew thyroid treatment had such moves?

Market Dynamics: The Plot Twists

The plot thickens with drivers and restraints. Increasing prevalence of thyroid disorders and treatment advancements keep the story alive. But, alas, the high cost of thyroid medications and limited diagnostic facilities add a dash of suspense. It’s like a medical thriller; will the market conquer these challenges?

Recent Developments: The Sequels

In the world of healthcare blockbusters, companies like AbbVie Inc. and Ipsen SA are making moves. Acquisitions and partnerships are the sequels to watch. It’s a saga of advancements, buyouts, and innovations, keeping us on the edge of our seats.

Closing Scene: The SkyQuest Analysis

As we near the final act, SkyQuest’s ABIRAW (cue the superhero music) steps in with promising prospects. The global thyroid gland disorders treatment market is set for growth, driven by awareness, rising thyroid issues, and the magic touch of technology. The cast includes precision medicine, targeted drug development, and the ever-charming AI and telemedicine.

The Finale: Thyroid Tales Unleashed

And there you have it, dear readers — a sneak peek into the thyroid maze. The market is evolving, players are making moves, and our thyroids? Well, they continue to be the enigmatic stars of this health drama. Until next time, keep those thyroids in check, and remember, it’s not a medical soap opera; it’s just thyroid tales unleashed.

About Us-

SkyQuest Technology Group is a Global Market Intelligence, Innovation Management & Commercialization organization that connects innovation to new markets, networks & collaborators for achieving Sustainable Development Goals.

Contact Us-

SkyQuest Technology Consulting Pvt. Ltd.

1 Apache Way,

Westford,

Massachusetts 01886

USA (+1) 617–230–0741

Email- info@skyquestt.com

Website: https://www.skyquestt.com

[market-spy]

Navigating the Thyroid Maze: A Peek into the World of Thyroid Gland Disorders Treatment

Welcome, curious minds, to the fascinating realm of thyroid gland disorders treatment. No capes, no superheroes, but a booming market poised to hit the $3.14 billion mark by 2031. Hold on to your hats; we’re about to dive into a world where thyroid troubles are met with innovation, a touch of sarcasm, and maybe a pinch of levothyroxine.

The Global Thyroid Scene: A Growth Odyssey

In the vast landscape of healthcare, the thyroid gland treatment market stands tall at a whopping $2.37 billion in 2022. Why the surge? Well, it seems our thyroids are getting chatty and causing a ruckus globally. Blame it on the expanding aging populations, better medical tech, or just the thyroid being the rebellious teenager of our endocrine system.

Treatment Tango: New Moves and Partnerships

Enter stage left: customized medicine techniques and novel drugs strutting their stuff. North America and Europe take the lead in this dance, with their higher rates of thyroid troubles and an iron grip on the healthcare kingdom. But wait, there’s a plot twist! Emerging economies in Latin America and Asia-Pacific are waltzing in, with improved healthcare infrastructure and growing awareness.

Telemedicine: The Thyroid Whisperer

In the ever-evolving healthcare landscape, telemedicine takes the spotlight. Imagine sitting in your PJs, consulting about your thyroid with a doctor miles away. Telehealth services are all the rage for endocrinology consultations, medication management, and those oh-so-fun routine check-ups. It’s like having a medical genie in your smartphone — magic, right?

Market Snapshot: The Thyroid Soap Opera

Fasten your seatbelts; we’re about to witness the grand spectacle of market snapshots. Thyroidectomy takes center stage as the largest segment, while radioiodine therapy steals the show as the fastest-growing sensation. With a 3.17% CAGR, the global thyroid gland disorders treatment market is indeed giving us a gripping saga.

For More Information: https://www.skyquestt.com/report/thyroid-gland-disorders-treatment-market

The Players in This Health Drama

Hold on, we’ve got stars in this show — AbbVie Inc., Pfizer Inc., and more. These pharmaceutical juggernauts are engaged in a fierce competition, racing to develop groundbreaking medications and formulations. It’s like the Oscars, but for thyroid treatment. Cue the red carpet!

Regional Rollercoaster: From North America to APAC

North America, particularly the US, takes the crown, thanks to widespread thyroid troubles and a well-oiled healthcare system. But wait, there’s an underdog climbing the ladder — the Asia-Pacific (APAC) region. China and India are in the spotlight, dancing to the tune of changing lifestyles and rising healthcare costs. Who knew thyroid treatment had such moves?

Market Dynamics: The Plot Twists

The plot thickens with drivers and restraints. Increasing prevalence of thyroid disorders and treatment advancements keep the story alive. But, alas, the high cost of thyroid medications and limited diagnostic facilities add a dash of suspense. It’s like a medical thriller; will the market conquer these challenges?

Recent Developments: The Sequels

In the world of healthcare blockbusters, companies like AbbVie Inc. and Ipsen SA are making moves. Acquisitions and partnerships are the sequels to watch. It’s a saga of advancements, buyouts, and innovations, keeping us on the edge of our seats.

Closing Scene: The SkyQuest Analysis

As we near the final act, SkyQuest’s ABIRAW (cue the superhero music) steps in with promising prospects. The global thyroid gland disorders treatment market is set for growth, driven by awareness, rising thyroid issues, and the magic touch of technology. The cast includes precision medicine, targeted drug development, and the ever-charming AI and telemedicine.

The Finale: Thyroid Tales Unleashed

And there you have it, dear readers — a sneak peek into the thyroid maze. The market is evolving, players are making moves, and our thyroids? Well, they continue to be the enigmatic stars of this health drama. Until next time, keep those thyroids in check, and remember, it’s not a medical soap opera; it’s just thyroid tales unleashed.

About Us-

SkyQuest Technology Group is a Global Market Intelligence, Innovation Management & Commercialization organization that connects innovation to new markets, networks & collaborators for achieving Sustainable Development Goals.

Contact Us-

SkyQuest Technology Consulting Pvt. Ltd.

1 Apache Way,

Westford,

Massachusetts 01886

USA (+1) 617–230–0741

Email- info@skyquestt.com

Website: https://www.skyquestt.com

[hyenaswine]

want 2 scream bc i got an update about the i-131 yesterday but my phone did not notify me of the email. why can't these people call on the phone like regular professionals. i sit at home all day waiting for a phone call, not wanting to go out or do anything cuz this is so important to me that i'm terrified of missing it, & it ends up being a fucking email that i don't see until 24 hours later. i know he's not actively dying but this feels dire to me at this point & i guess i gotta stop being dramatic & gain some perspective about it but i'm so tired of waiting. i'm so tired of him being so skinny & unable to digest his food properly & shitting shitting shitting all the time.

anyway, they're supposed to call in the next week or so for a phone consult & then schedule treatment for may.

"Radioiodine is a truly wonderful procedure. I'm excited to be able to offer this to Bubo" <- liked this part

[mcatmemoranda]

Hypothyroidism

Clinical features – The clinical manifestations of hypothyroidism are highly variable, depending upon the age at onset and the duration and severity of thyroid hormone deficiency. Common symptoms of thyroid hormone deficiency include fatigue, cold intolerance, weight gain, constipation, dry skin, myalgia, and menstrual irregularities. Physical examination findings may include goiter (particularly in patients with iodine deficiency or goitrous chronic autoimmune thyroiditis [Hashimoto's thyroiditis]), bradycardia, diastolic hypertension, and a delayed relaxation phase of the deep tendon reflexes. Serum concentrations of thyroid peroxidase (TPO) autoantibodies are elevated in more than 90 percent of patients with hypothyroidism due to chronic autoimmune hypothyroidism (Hashimoto's thyroiditis).

●Diagnosis – The diagnosis of hypothyroidism is based primarily upon laboratory testing. In most patients with symptoms suggestive of hypothyroidism, the serum thyroid-stimulating hormone (TSH) should be the initial test. If the serum TSH concentration is elevated, the TSH measurement should be repeated along with a serum free thyroxine (T4) to make the diagnosis of hypothyroidism. If central hypothyroidism is suspected (eg, presence of pituitary or hypothalamic disease), or if the patient has convincing symptoms of hypothyroidism despite a normal TSH result, we measure serum TSH and free T4.

•Overt primary hypothyroidism – If the repeat serum TSH value is still high and the serum free T4 is low, suggesting primary hypothyroidism, replacement therapy with T4 should be initiated.

•Subclinical hypothyroidism – Patients with a high serum TSH concentration and a normal serum free T4 concentration may have subclinical hypothyroidism.

•Central hypothyroidism – In patients with central hypothyroidism, the serum free T4 value is low-normal or low and serum TSH may be frankly low, inappropriately normal (for the low T4), or slightly high (5 to 10 mU/L) due to secretion of biologically inactive TSH.

●Differential diagnosis – The differential diagnosis of an elevated serum TSH concentration includes resistance to TSH, recovery from nonthyroidal illness, and a TSH-secreting pituitary adenoma.

●Identifying the cause of hypothyroidism – The clinical evaluation of a patient with primary hypothyroidism should be directed toward confirming the presence and identifying the cause of the hormone deficiency. The history, for example, may uncover past treatment of hyperthyroidism with radioiodine or thyroidectomy, the use of drugs that affect thyroid hormone synthesis, or history of iodine deficiency or excess. We do not routinely measure TPO antibodies in patients with primary overt hypothyroidism, because almost all have chronic autoimmune thyroiditis.

●Screening

•We suggest not performing population-based screening for hypothyroidism (Grade 2C). As an alternative, we prefer to screen individuals who are at increased risk for hypothyroidism.

•Measurement of serum TSH (rather than free T4 or total T4) is an excellent screening test for hypothyroidism in ambulatory patients. However, TSH alone may not be a useful tool for the diagnosis of hypothyroidism if pituitary or hypothalamic disease is known or suspected; in hospitalized patients, since there are many other factors in acutely or chronically ill euthyroid patients that influence TSH secretion; and in patients receiving drugs or with underlying diseases that affect TSH secretion.

•The universal screening of asymptomatic pregnant women for hypothyroidism during the first trimester of pregnancy is controversial. We suggest a targeted approach rather than universal screening (Grade 2C). We favor screening pregnant women if they are from an area of moderate to severe iodine insufficiency, have symptoms of hypothyroidism, a family or personal history of thyroid disease, or a personal history of TPO antibodies, type 1 diabetes, class 3 obesity, head and neck radiation, recurrent miscarriage, or infertility.