Tumgik
#so like he had some cranberry supplements he was getting after a uti
greyias · 9 months
Text
🙃
Purina apparently discontinued and then reformulated the only canned food I've found so far that Griffin's extraordinarily sensitive tummy can tolerate, adding one of his potential worst allergens to nearly the top of the formulation list. I have sent a Karen-like e-mail to Purina, and am now having to have five million tabs open on different pet food websites to put the ingredient lists of everything under a microscope to try and find something remotely close.
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satorusugurugurl · 16 days
Note
Hiii can i request reader x gojo, where reader keeps ruining his orgasm n just messing with him? And he’s all whiny and begging and shit? 🥺👉👈
Cranberry Juice and Rings
Pairing: Gojo Satoru x FAB!Reader
Word Count: 1,725
Warnings: Edging, orgasm denial, smut, whinny Gojo, dirty talk, sexting, toys
A/N: Ah, nothing like a good old whing Gojo fic! I love whimpering, groaning men!
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Satoru was known by many as a pain in the ass. He was arrogant and cocky, but that didn’t stop you from loving him. He was one of your favorite people, a goofball, and he spoiled you rotten. You couldn’t have asked for a better partner.
But he was Gojo Satoru. Some days, he was unbearable to deal with, even for you. Days like today, for example. You had gotten a nasty UTI and were on a strict sex ban for a week. Gojo had been kind the first few days, picking up your prescription along with cranberry juice and supplements. By day four of the sex ban, he was pent up and decided it would be fun to tease you relentlessly. He started sexting you, sending you pictures and voice memos that had you clenching your thighs to try to ease the throbbing between your legs.
Satoru: I’m so sweaty! Look, it’s running down my V-line, baby~!
You: Stop trying to turn me on asshole. I literally cannot flick my bean or have sex for the next three days.
Satoru: Oh? That sucks for you. I don’t have to deal with that.
The man then proceeded to send you a video of him jerking off in the bathroom. If you didn’t feel like razors sliced you each time you used the bathroom, you would have found him and made him pay for a new pair of underwear and take care of the mess he had turned you into. However, the unpleasant throbbing between your legs prevented you from acting upon your desires.
You: Keep it up, Satoru. I will make you regret your choices.
Satoru: Oooh, I’m so scared~!
Your dear, sweet, idiotic boyfriend did not heed your warning. He only seemed to get worse after your ominous threat. Three days of torture later, Satoru eagerly ra into your shared condo, his calendar chiming with a reminder today was the day your medical sex ban was lifted. He has a week's worth of pussy eating to make up for, and he planned to take his time with you.
”Sweetheart!” He sang out, making his way through the condo. “I hope you’re ready!” Stepping inside the bedroom, Satoru blinked, finding you sitting on the edge of the bed in your sky-blue lace set. “What a good girl you are!” Drooping to his knees before you, he clapped his hands together. “Thanks for the mea—“
”Shut the fuck up and get on the bed.”
The stern tone of your voice has Satoru staring. “I’m sorry?” His smile was full of confusion as he forced your legs apart. “I said thanks for the meal, didn’t I?” Satoru began to dip his head between your thighs, but before he could reach your sweet, dripping core, you put your foot on his forehead, pushing him away. “Hey!” His bottom lip stuck out in a pout.
“Didn’t I warn you I would make you regret sending me all those thirst trap pictures and messages?”
”H-Huh?”
”I said, didn’t I warn you I would make you regret your choices?”
”W-Well, I m-mean you did, but I—“
”Good, boy.” A round silicon ring hit him in the face. “Now put that on and get on the bed.” Gulping, Satoru shakily did as you commanded, regret setting in the pit of his stomach as he did.
Any hopes for mercy went out the window as you bounced up and down on his cock as he sat upright against the headboard. You were grinning, hands gripping his shoulders as you came around him, pulling off, denying him the pleasure of feeling your cum, denying his orgasm for the third fucking time.
”F-Fuck Toru~ you’re such a good dildo.”
”S-Sweetheart—please, baby, I need you.”
”You need me?” You questioned with faux sympathy. “Oh, sweet boy, am I teasing you too much?” A delicate hand wrapped around his red throbbing length, the cock ring preventing him from cumming, thus making him ten times more sensitive.
”A-Ah! Yes, yes, baby, please, please, I need you!” Blue eyes watched as you stroked your hand up and down, pre-cum dribbled out of his tip, running over your manicured nails. “Oh fuck, I can feel it, keep going, keep going don’t stop!”
“Yeah?” Satoru cried out as you wrapped your other hand around him. Your hands squeezed his shaft as you moved them up and down, smirking as he whimpered, eyes transfixed on your tiny hands as his mouth opened in an ‘O’ shape. “Are you close, Toru? Are you going to make a mess for me?”
“Yes! Yes! Yes!”
”Gonna cum pretty boy?”
”Fuck yes! Oooh fuck I’m so close, so fucking close, almost there, almost there!”
The second you saw white lashes flutter, you yank your hands away, preventing him from reaching his sweet release. Your boyfriend’s eyes narrowed and shot open in disbelief, focusing on the throbbing, swollen red tip that sobbed pre-cum instead of actual cum. His dick looked as upset as him, the intense orgasm fading.
”Babe!” Satoru threw his head back against the wooden frame with a pathetic whine. “I wanna cum!” Reaching out, you gently rubbed the pad of your thumb over his bottom lip.
”You wanna cum?”
”Yes, so bad!”
You straddled his hips with a hum, lowering yourself back down onto his velvety shaft with a satisfied moan. “Well, that sucks for you, I don’t have to deal with that.” You quoted his text before dragging your tight wet pussy up and down his swollen cock.
Satoru cried out, whining as you used his cock like it was a sex toy. This was literal torture, feeling your wet, warm walls clamp down around him, watching you tilt your head back in pleasure. Even hearing your moans fill the bedroom was driving him insane. You looked so hot and beautiful when you used him like this. He just wished he could be holding onto your hips, fucking his cock up into you, filling you with his cum as you both lost yourselves in pure orgasmic bliss. Lips moving against lips, swallowing each other, moans as you came down.
Instead, Satoru was crying out, whimpers sounding in the back of his throat. His hands fisted the sheets as he bit down on the inside of his cheek. He had thought teasing you this week was all fun and games! Get you all worked up and desperate for him to rearrange your insides. In his horny mind, it was like mental edging without touching
Yourself. What a terrible mistake that had been. The only one having fun and getting off at the current moment was you. While he suffered from the worst case of blue balls in his entire life.
“Shit! Oooh, shit!” Your brows furrowed as you cried out, reaching down and rubbing your clit. “C-Cumming~! Cumming Toru!” Just as your orgasm hit, you pulled off of him, squirting all over his stomach and cock with a squeal.
“F-Fuck, oh god.” Satoru quickly grabbed his cock, stroking himself off while you came all over him. “So hot~ so fucking hot!”
You recovered just in time to see Satoru jerking himself off, the tips of his ears turning red as his eyes began to roll back. “Nuh-uh!” swatting his hands away, Satoru groaned. “Bad boy!” When he reached for his swollen cock again. You grab both his wrists, pinning them down on either side of him. “I said no!” Poor Satoru cried out in frustration, tears welling in his eyes.
“Sweetie, baby, please.” He sobbed, cock dribbling more pre-cum onto his lower abdomen. “Please let me cum, please, baby, please! I'm sorry I was such an ass this week. I won't ever do it again!” Fingers gripped the sheets underneath him. “Please let me cum! Please!” Those tears filling his eyes finally spilled over his white lashes, staining his flushed cheeks.
“Oh, my baby~” Leaning in, you locked the salty tears up with the tip of your tongue. “You learned your lesson?”
“Uh-huh!” Satoru hiccuped as more tears streamed down his face.
“You see how it's not nice to tease? How cruel is it to cum in front of your partner when you're unable to do anything?”
“Yes! I’m sorry, honey! So sorry!”
Releasing both his wrists, you grabbed the sparkly blue cock ring that was securely on his base. “Good boy, Toru.” As soon as the toy was off, Satoru shoved you off, pushing you into the mattress. “Ooh fuck!” Giggled erupted as he threw both your feet over his shoulders before sliding into you.
“So good! S-aS good!” He cried out, throwing his head back, crying softly, and he slammed on and out of you. “I’m going to cum! Please cum with me! Milk my cock, baby! Milk it!”
“Yes, Toru! Cum inside of me, baby!” Your fingers found your clit with ease, rubbing it back and forth, whimpering as Satoru twitched inside of you. “Cum on, baby~ cum for me!”
Satoru’s jaw dropped open, eyes clamped shut as he cried out. He was crying out your name, whining, and whimpering like a cat in heat. Thick ropes of cum painted your insides, filling you to the absolute brim, leaving you crying out with him. He rubbed his hips against you, only stopping when his eyes rolled back, dizziness overcoming him.
He collapsed onto your chest, full weight resting on you as he whimpered into the crook of your neck. He could stay like this forever, but just as he found himself dozing off, you were tapping on his shoulders. Lazily lifting his head, cerulean eyes met yours.
“Five minutes; I’m pushing you off if you stay inside me any longer.”
“Huh? Why?” Your boyfriend panted out.
“The last time we fell asleep like this, I got a UTI!”
“Mmm, it’s fine.” he’s sleepy, wrapped his arms around you. “Just five minutes.” you relaxed against him as he agreed on your time limit. “I love you, sweetheart.”
“I love you too, Satoru.” as he snuggled in closer, humming sleepily, you smiled, fingers brushing strands of hair off his brow. Maybe ten minutes wouldn’t hurt.
Forever Tag List!
@darkstarlight82 @pandoness
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drferox · 7 years
Note
What do you think of ~~natural~~ homeopathic medicine? I get that it can be great complementary treatment, but you really can't argue with science. I once had a friend try to cure her dog's UTI with cranberry juice and essential oils - no antibiotics. It didn't work, and he ended up needing emergency treatment.
Homeopathy is a system of “medical” practice that treats a disease especially by the administration of minute doses of a remedy that would in larger amounts produce in healthy persons symptoms similar to those of the disease.
Homeopathic remedies are diluted so much that it is unlikely even a single molecule of the thing being ‘diluted’ remains in the administered water. It’s water and wishful thinking. It’s a placebo at best, it’s not medicine and it’s not science.
Using cranberry juice and essential oils might fall under naturopathy, or generic home remedies, but they’re only useful in very specific situations. It’s not always appropriate to use a ‘natural remedy’ intended for humans in an animal patient, because the pathophysiology might not be the same.
Essential Oil use in animals makes me very angry. There is no benefit to using them - any benefits listed are vague, non-specific, or outright wrong.
Do NOT apply essential oils to your pets. I don’t care if a certain ‘natural’ magazine published something saying you could put lavender oil on burns, do NOT do it. It does nothing to help, actively harms, and delays proper treatment.
Using essential oils on species with an excellent sense of smell borders on cruelty. That stuff is hard for us to get off, and I’ve seen half a dozen pets that have become so distressed that they’ve presented to the emergency clinic after hours because some well-meaning individual believed an article that basically claimed essential oils would work like magic and fix their pet’s problem.
Do not use essential oils on pets.
There are a handful of complementary treatments that do actually have some use, especially with chronic pain conditions. Without listing every single one that might have some benefit, the most common one I use is glucosamine and chondroitin. Used together these supplements can reduce symptoms of arthritic pain by up to 40% after 6 weeks. That’s not great on its own, but still useful as anything that reduced chronic pain is a good thing.
As a confession, I’ve done courses on ‘Healing with Herbs’. I wanted to believe in this stuff, but the science for most of it is weak, mostly human based, and so much of it is wishful thinking. I use it when and only when there is evidence to do so, and only use products that I have a high degree of trust will actually only contain what it says on the box.
A few clues that the ‘natural’ cure/treatment isn’t all it’s cracked up to be:
If a source is telling you that vets and animal health professionals either don’t know what they’re talking about, or are lying to you.
If it claims multiple, very different benefits that are difficult or impossible to quantify or measure
If there are untrackable, unverifiable testimonials saying how great the product is
If it promised rapid results
If it sounds too good to be true, it probably is
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jakehglover · 5 years
Text
Mannose: This Sugar Has Incredible Benefits
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Normally, sugar and cancer go together in a negative way. Because a growing number of studies show sugar feeds cancer1,2,3,4 and plays a role in most chronic disease,5 I typically advise you eliminate refined sugar from your diet. I also recommend you limit your fructose consumption for similar reasons. Even when consumed in the form of whole fruit, fructose may be harmful to your health if eaten excessively.
Now, research out of Scotland suggests a type of sugar called mannose, found in cranberries and other fruits, may be useful in the treatment of certain cancers. In experiments involving lab mice, mannose was shown to interfere with the ability of cancerous tumors to take up glucose. It also boosted the effectiveness of chemotherapy drugs.
Mannose Shown to Suppress Cancer in Lab Mice
While sugar has been shown to fuel cancer growth, a team of European researchers, most of whom represent the Cancer Research UK Beatson Institute for Cancer Research at Scotland’s University of Glasgow, have found quite the opposite.
In experiments involving lab mice, Kevin Ryan, Ph.D., professor of molecular cell biology at the University of Glasgow, and his colleagues found mannose:6,7,8
Slowed the growth of multiple cancers, including lung, pancreatic and skin, presumably by interfering with the ability of cancerous tumors to take up glucose
Reduced the size of cancerous tumors
Boosted the effectiveness of cancer drugs — specifically cisplatin and doxorubicin, two of the most widely used chemotherapy medications
Did not affect the weight or health of the mice
Mannose also increased the life span of some of the mice. The results of their research were published in the November 2018 issue of the journal Nature.9 To date, mannose has been used as a natural treatment for cystitis (inflammation of the bladder) and urinary tract infections (UTIs).
After Ryan and his team added mannose to the drinking water of mice suffering from lung, pancreatic or skin cancer, they noticed tumor growth slowed. In addition, they noted no obvious side effects to the mice treated with mannose.
“Tumors need a lot of glucose to grow, so limiting the amount they can use should slow cancer progression,” said Ryan. “The problem is that normal tissues need glucose, as well, so we can’t completely remove it from the body.”10
As such, the researchers had to find a dose of mannose sufficient to block glucose such that it slowed tumor growth, but allowed normal tissues to remain unaffected. “This is early research, but it is hoped that finding this perfect balance means that, in the future, mannose could be given to cancer patients to enhance chemotherapy without damaging their overall health,” Ryan stated.11
Beyond the cancers mentioned above, the team exposed cells from other types of cancer — including bone, bowel, leukemia and ovarian — to mannose. Some of the cancer cells responded well to mannose while others did not. About this, one source noted, “The anticancer potential of mannose appeared to depend on whether an enzyme that breaks down the sugar was present in cells.”12
Should You Use Cranberry Juice to Treat UTIs or Cancer?
Very likely you’ve been told that drinking cranberry juice can soothe cystitis and UTIs. Now, the current research seems to suggest it can be used to treat cancer. As such, you may be thinking about loading up on cranberry juice, which I do not recommend.
First, while the use of mannose to treat bladder and urinary tract issues is well founded, I advise you to avoid cranberry juice as a medical treatment. That’s because you’d have to drink a lot of juice, which is often laden with toxic amounts of sugar.
For those conditions, consult your medical practitioner to ensure an accurate diagnosis and then inquire about the possible use of a mannose-containing supplement. Second, with respect to cancer treatment and mannose, keep in mind this research is preliminary and has yet to be tested on humans.
With respect to that, Ryan commented, “Our next step is investigating why [the] treatment only works in some cells, so that we can [determine] which patients might benefit the most from this approach.” He expressed his desire to see clinical trials begin on mannose “as soon as possible to determine its true potential as a new cancer therapy.”
Martin Ledwick, Cancer Research UK’s head information nurse, joined Ryan in cautioning cancer patients to resist the temptation to self-medicate with mannose. Ledwick said:
“Although these results are very promising for the future of some cancer treatments, this is very early research and has not yet been tested in humans.
Patients should not self-prescribe mannose as there is a real risk of negative side effects that haven’t been tested for yet. It’s important to consult with a doctor before drastically changing your diet or taking new supplements.”
The bottom line is it’s difficult to regulate your body’s glucose levels in a healthy manner through self-experimentation. This is particularly the case if you are dealing with a serious illness like cancer or diabetes. While mannose may be a useful complementary treatment, I also encourage you to:
Eat a healthy, whole food diet, which implies avoiding processed foods and sugar, especially soda and sweets
Exercise regularly
Get at least seven to nine hours of high-quality sleep every night
Reach out for or continue receiving treatment from professional health care practitioners who are familiar with your condition and experienced in natural approaches
What Is Mannose and How Does It Work?
As mentioned, mannose is a monosaccharide found in cranberries and other fruits, including apples, blueberries, oranges and peaches. It also resides in vegetables like broccoli, cabbage and green beans.
About this simple sugar, The Clinical Advisor says, “In addition, d-mannose occurs naturally in some cells in the human body and is thought to be a prebiotic, because consumption of d-mannose stimulates and fosters the growth of good bacteria in the digestive tract.”
Beyond its presence in whole foods and your body, mannose also commonly appears in supplement form under the name D-mannose. Although mannose is chemically considered a simple sugar, structurally, it is similar to glucose.
That said, it is absorbed more slowly in your gastrointestinal tract than glucose, which accounts for its lower glycemic index. With respect to this aspect of mannose, The Clinical Advisor notes:
“Compared with actual glucose, which is readily absorbed and has a glycemic index of 100, mannose must first be converted into fructose and then into glucose, significantly blunting the insulin response and reducing its impact on blood sugar levels.
After mannose is absorbed by the gut, it is not stored in the liver like glucose, but is filtered out of the body directly by the kidneys.”
For the experiments in which mannose was given to lab mice afflicted by cancers such as bone, bowel, leukemia and ovarian, mannose was shown to more readily disrupt cells that had lower levels of an enzyme called phosphomannose isomerase (PMI). About the impact of PMI, the study authors stated:
“Cells with low levels of PMI are sensitive to mannose, whereas cells with high levels are resistant. … PMI levels also vary greatly between different patients and different tumor types, indicating that PMI levels could be used as a biomarker to direct the successful administration of mannose. …
[T]he administration of mannose could be a simple, safe and selective therapy in the treatment of cancer, and could be applicable to multiple tumor types.”
Research Validates Mannose for Treating Rare Disease CDG and UTIs
D-mannose has been shown to help in the treatment of a rare disease called carbohydrate-deficient glycoprotein syndrome type 1b (CDG 1b). This condition is passed down through families and is characterized by liver and digestive problems associated with hyperinsulinism and inconstant thrombosis. Beyond that, the condition causes your body’s blood coagulation factors to be decreased.
About CDG 1b and mannose, authors of a 2009 study commented, “In our experience, mannose given orally at least four times per day not only transformed lethal CDG 1b into a treatable disease, but also improved the general condition and digestive symptoms of all reported patients but one.”17
As mentioned, D-mannose is commonly used to prevent and treat UTIs, which are usually caused when E. coli bacteria is transferred from your intestinal tract to your urinary tract. D-mannose is great for UTIs because it attaches to the E. coli bacteria, causing them to stick to each other instead of clinging to the walls of your urinary tract.
Under those conditions, the harmful bacteria can be eliminated from your body during urination. Given the increasing instances of antibiotic resistance, natural remedies for UTIs are imperative.
A 2014 study published in the journal World Journal of Urology found D-mannose powder to be as effective as an antibiotic in treating recurrent UTIs in women. A total of 308 women were divided into three groups:18
The first group received 2 grams (g) of D-mannose powder mixed in water daily for six months
A second group was given 50 milligrams (mg) of the antibiotic Nitrofurantoin daily
The third group was a control group and received no treatment
Of the 98 patients experiencing a recurrent UTI, just 15 percent of them consumed D-mannose, whereas 20 percent took the antibiotic and 61 percent received no treatment.
With respect to the outcomes, the study authors said, “D-mannose powder significantly reduced the risk of recurrent UTI, which was no different from [the] Nitrofurantoin group. More studies will be needed to validate the results … but initial findings show that D-mannose may be useful for UTI prevention.”19
If you have been plagued by recurrent UTIs or bladder inflammation, particularly if you are concerned about antibiotic resistance, now may be the time to talk to your health care practitioner about trying D-mannose. It is generally quite effective for up to 90 percent of UTI cases.
The only exception would be UTIs caused by a bacterium other than E. coli; in that case, you’d be better served to ask your doctor about supplements known to disrupt biofilms.20
Mannose Contributes to the Healing Properties of Aloe Vera
While you probably know aloe vera is beneficial for soothing burns, improving wound healing and inhibiting inflammation, you may not be aware that the major sugar in aloe vera is mannose. In a 1994 study, lab mice receiving 300 mg/kilogram (kg) of mannose-6-phosphate showed improved wound healing compared to those treated with saline controls.
The researchers noted, “This dose also had anti-inflammatory activity.”1` Authors of a 2004 study added, “The clear pulp, also known as inner gel, of [the] Aloe vera L. leaf is widely used in various medical, cosmetic and nutraceutical applications. Many beneficial effects of this plant have been attributed to the polysaccharides present in the pulp.”22
Another source states, “High concentrations of mannan saccharides are available in the gel of aloe plants. Laboratory studies show the effects of glucomannan saccharides signals as they activate the immune response through increased expressions of interleukin-1, interleukin-6 and tumor necrosis factor.”
Cautions About Taking Mannose
While mannose is thought to be well tolerated in most people, I do not recommend supplementing with it if you are pregnant or breastfeeding due to the lack of research validating its safe use. That said, pregnant and breastfeeding moms should be fine consuming mannose-containing foods, assuming it is done in moderation. 
The side effects associated with mannose may include bloating and loose stools. Beyond that, since mannose could make it harder to regulate your blood sugar if you have diabetes, use caution when taking D-mannose supplements if you are diabetic.
While the news about mannose as a potential cancer fighter is encouraging, more research, including clinical trials, is needed to validate its effectiveness. For your safety, always consult a medical professional before taking a new supplement or changing the dosing associated with any of your existing supplements.
from HealthyLife via Jake Glover on Inoreader http://articles.mercola.com/sites/articles/archive/2018/12/10/mannose-health-benefits.aspx
0 notes
jerrytackettca · 5 years
Text
Mannose: This Sugar Has Incredible Benefits
Normally, sugar and cancer go together in a negative way. Because a growing number of studies show sugar feeds cancer1,2,3,4 and plays a role in most chronic disease,5 I typically advise you eliminate refined sugar from your diet. I also recommend you limit your fructose consumption for similar reasons. Even when consumed in the form of whole fruit, fructose may be harmful to your health if eaten excessively.
Now, research out of Scotland suggests a type of sugar called mannose, found in cranberries and other fruits, may be useful in the treatment of certain cancers. In experiments involving lab mice, mannose was shown to interfere with the ability of cancerous tumors to take up glucose. It also boosted the effectiveness of chemotherapy drugs.
Mannose Shown to Suppress Cancer in Lab Mice
While sugar has been shown to fuel cancer growth, a team of European researchers, most of whom represent the Cancer Research UK Beatson Institute for Cancer Research at Scotland’s University of Glasgow, have found quite the opposite.
In experiments involving lab mice, Kevin Ryan, Ph.D., professor of molecular cell biology at the University of Glasgow, and his colleagues found mannose:6,7,8
Slowed the growth of multiple cancers, including lung, pancreatic and skin, presumably by interfering with the ability of cancerous tumors to take up glucose
Reduced the size of cancerous tumors
Boosted the effectiveness of cancer drugs — specifically cisplatin and doxorubicin, two of the most widely used chemotherapy medications
Did not affect the weight or health of the mice
Mannose also increased the life span of some of the mice. The results of their research were published in the November 2018 issue of the journal Nature.9 To date, mannose has been used as a natural treatment for cystitis (inflammation of the bladder) and urinary tract infections (UTIs).
After Ryan and his team added mannose to the drinking water of mice suffering from lung, pancreatic or skin cancer, they noticed tumor growth slowed. In addition, they noted no obvious side effects to the mice treated with mannose.
“Tumors need a lot of glucose to grow, so limiting the amount they can use should slow cancer progression,” said Ryan. “The problem is that normal tissues need glucose, as well, so we can’t completely remove it from the body.”10
As such, the researchers had to find a dose of mannose sufficient to block glucose such that it slowed tumor growth, but allowed normal tissues to remain unaffected. “This is early research, but it is hoped that finding this perfect balance means that, in the future, mannose could be given to cancer patients to enhance chemotherapy without damaging their overall health,” Ryan stated.11
Beyond the cancers mentioned above, the team exposed cells from other types of cancer — including bone, bowel, leukemia and ovarian — to mannose. Some of the cancer cells responded well to mannose while others did not. About this, one source noted, “The anticancer potential of mannose appeared to depend on whether an enzyme that breaks down the sugar was present in cells.”12
Should You Use Cranberry Juice to Treat UTIs or Cancer?
Very likely you’ve been told that drinking cranberry juice can soothe cystitis and UTIs. Now, the current research seems to suggest it can be used to treat cancer. As such, you may be thinking about loading up on cranberry juice, which I do not recommend.
First, while the use of mannose to treat bladder and urinary tract issues is well founded, I advise you to avoid cranberry juice as a medical treatment. That’s because you’d have to drink a lot of juice, which is often laden with toxic amounts of sugar.
For those conditions, consult your medical practitioner to ensure an accurate diagnosis and then inquire about the possible use of a mannose-containing supplement. Second, with respect to cancer treatment and mannose, keep in mind this research is preliminary and has yet to be tested on humans.
With respect to that, Ryan commented, “Our next step is investigating why [the] treatment only works in some cells, so that we can [determine] which patients might benefit the most from this approach.” He expressed his desire to see clinical trials begin on mannose “as soon as possible to determine its true potential as a new cancer therapy.”
Martin Ledwick, Cancer Research UK’s head information nurse, joined Ryan in cautioning cancer patients to resist the temptation to self-medicate with mannose. Ledwick said:
“Although these results are very promising for the future of some cancer treatments, this is very early research and has not yet been tested in humans.
Patients should not self-prescribe mannose as there is a real risk of negative side effects that haven’t been tested for yet. It’s important to consult with a doctor before drastically changing your diet or taking new supplements.”
The bottom line is it’s difficult to regulate your body’s glucose levels in a healthy manner through self-experimentation. This is particularly the case if you are dealing with a serious illness like cancer or diabetes. While mannose may be a useful complementary treatment, I also encourage you to:
Eat a healthy, whole food diet, which implies avoiding processed foods and sugar, especially soda and sweets
Exercise regularly
Get at least seven to nine hours of high-quality sleep every night
Reach out for or continue receiving treatment from professional health care practitioners who are familiar with your condition and experienced in natural approaches
What Is Mannose and How Does It Work?
As mentioned, mannose is a monosaccharide found in cranberries and other fruits, including apples, blueberries, oranges and peaches. It also resides in vegetables like broccoli, cabbage and green beans.
About this simple sugar, The Clinical Advisor says, “In addition, d-mannose occurs naturally in some cells in the human body and is thought to be a prebiotic, because consumption of d-mannose stimulates and fosters the growth of good bacteria in the digestive tract.”
Beyond its presence in whole foods and your body, mannose also commonly appears in supplement form under the name D-mannose. Although mannose is chemically considered a simple sugar, structurally, it is similar to glucose.
That said, it is absorbed more slowly in your gastrointestinal tract than glucose, which accounts for its lower glycemic index. With respect to this aspect of mannose, The Clinical Advisor notes:
“Compared with actual glucose, which is readily absorbed and has a glycemic index of 100, mannose must first be converted into fructose and then into glucose, significantly blunting the insulin response and reducing its impact on blood sugar levels.
After mannose is absorbed by the gut, it is not stored in the liver like glucose, but is filtered out of the body directly by the kidneys.”
For the experiments in which mannose was given to lab mice afflicted by cancers such as bone, bowel, leukemia and ovarian, mannose was shown to more readily disrupt cells that had lower levels of an enzyme called phosphomannose isomerase (PMI). About the impact of PMI, the study authors stated:
“Cells with low levels of PMI are sensitive to mannose, whereas cells with high levels are resistant. … PMI levels also vary greatly between different patients and different tumor types, indicating that PMI levels could be used as a biomarker to direct the successful administration of mannose. …
[T]he administration of mannose could be a simple, safe and selective therapy in the treatment of cancer, and could be applicable to multiple tumor types.”
Research Validates Mannose for Treating Rare Disease CDG and UTIs
D-mannose has been shown to help in the treatment of a rare disease called carbohydrate-deficient glycoprotein syndrome type 1b (CDG 1b). This condition is passed down through families and is characterized by liver and digestive problems associated with hyperinsulinism and inconstant thrombosis. Beyond that, the condition causes your body’s blood coagulation factors to be decreased.
About CDG 1b and mannose, authors of a 2009 study commented, “In our experience, mannose given orally at least four times per day not only transformed lethal CDG 1b into a treatable disease, but also improved the general condition and digestive symptoms of all reported patients but one.”17
As mentioned, D-mannose is commonly used to prevent and treat UTIs, which are usually caused when E. coli bacteria is transferred from your intestinal tract to your urinary tract. D-mannose is great for UTIs because it attaches to the E. coli bacteria, causing them to stick to each other instead of clinging to the walls of your urinary tract.
Under those conditions, the harmful bacteria can be eliminated from your body during urination. Given the increasing instances of antibiotic resistance, natural remedies for UTIs are imperative.
A 2014 study published in the journal World Journal of Urology found D-mannose powder to be as effective as an antibiotic in treating recurrent UTIs in women. A total of 308 women were divided into three groups:18
The first group received 2 grams (g) of D-mannose powder mixed in water daily for six months
A second group was given 50 milligrams (mg) of the antibiotic Nitrofurantoin daily
The third group was a control group and received no treatment
Of the 98 patients experiencing a recurrent UTI, just 15 percent of them consumed D-mannose, whereas 20 percent took the antibiotic and 61 percent received no treatment.
With respect to the outcomes, the study authors said, “D-mannose powder significantly reduced the risk of recurrent UTI, which was no different from [the] Nitrofurantoin group. More studies will be needed to validate the results … but initial findings show that D-mannose may be useful for UTI prevention.”19
If you have been plagued by recurrent UTIs or bladder inflammation, particularly if you are concerned about antibiotic resistance, now may be the time to talk to your health care practitioner about trying D-mannose. It is generally quite effective for up to 90 percent of UTI cases.
The only exception would be UTIs caused by a bacterium other than E. coli; in that case, you’d be better served to ask your doctor about supplements known to disrupt biofilms.20
Mannose Contributes to the Healing Properties of Aloe Vera
While you probably know aloe vera is beneficial for soothing burns, improving wound healing and inhibiting inflammation, you may not be aware that the major sugar in aloe vera is mannose. In a 1994 study, lab mice receiving 300 mg/kilogram (kg) of mannose-6-phosphate showed improved wound healing compared to those treated with saline controls.
The researchers noted, “This dose also had anti-inflammatory activity.”1` Authors of a 2004 study added, “The clear pulp, also known as inner gel, of [the] Aloe vera L. leaf is widely used in various medical, cosmetic and nutraceutical applications. Many beneficial effects of this plant have been attributed to the polysaccharides present in the pulp.”22
Another source states, “High concentrations of mannan saccharides are available in the gel of aloe plants. Laboratory studies show the effects of glucomannan saccharides signals as they activate the immune response through increased expressions of interleukin-1, interleukin-6 and tumor necrosis factor.”
Cautions About Taking Mannose
While mannose is thought to be well tolerated in most people, I do not recommend supplementing with it if you are pregnant or breastfeeding due to the lack of research validating its safe use. That said, pregnant and breastfeeding moms should be fine consuming mannose-containing foods, assuming it is done in moderation. 
The side effects associated with mannose may include bloating and loose stools. Beyond that, since mannose could make it harder to regulate your blood sugar if you have diabetes, use caution when taking D-mannose supplements if you are diabetic.
While the news about mannose as a potential cancer fighter is encouraging, more research, including clinical trials, is needed to validate its effectiveness. For your safety, always consult a medical professional before taking a new supplement or changing the dosing associated with any of your existing supplements.
from http://articles.mercola.com/sites/articles/archive/2018/12/10/mannose-health-benefits.aspx
source http://niapurenaturecom.weebly.com/blog/mannose-this-sugar-has-incredible-benefits
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paullassiterca · 5 years
Text
Mannose: This Sugar Has Incredible Benefits
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Normally, sugar and cancer go together in a negative way. Because a growing number of studies show sugar feeds cancer1,2,3,4 and plays a role in most chronic disease,5 I typically advise you eliminate refined sugar from your diet. I also recommend you limit your fructose consumption for similar reasons. Even when consumed in the form of whole fruit, fructose may be harmful to your health if eaten excessively.
Now, research out of Scotland suggests a type of sugar called mannose, found in cranberries and other fruits, may be useful in the treatment of certain cancers. In experiments involving lab mice, mannose was shown to interfere with the ability of cancerous tumors to take up glucose. It also boosted the effectiveness of chemotherapy drugs.
Mannose Shown to Suppress Cancer in Lab Mice
While sugar has been shown to fuel cancer growth, a team of European researchers, most of whom represent the Cancer Research UK Beatson Institute for Cancer Research at Scotland’s University of Glasgow, have found quite the opposite.
In experiments involving lab mice, Kevin Ryan, Ph.D., professor of molecular cell biology at the University of Glasgow, and his colleagues found mannose:6,7,8
Slowed the growth of multiple cancers, including lung, pancreatic and skin, presumably by interfering with the ability of cancerous tumors to take up glucose
Reduced the size of cancerous tumors
Boosted the effectiveness of cancer drugs — specifically cisplatin and doxorubicin, two of the most widely used chemotherapy medications
Did not affect the weight or health of the mice
Mannose also increased the life span of some of the mice. The results of their research were published in the November 2018 issue of the journal Nature.9 To date, mannose has been used as a natural treatment for cystitis (inflammation of the bladder) and urinary tract infections (UTIs).
After Ryan and his team added mannose to the drinking water of mice suffering from lung, pancreatic or skin cancer, they noticed tumor growth slowed. In addition, they noted no obvious side effects to the mice treated with mannose.
“Tumors need a lot of glucose to grow, so limiting the amount they can use should slow cancer progression,” said Ryan. “The problem is that normal tissues need glucose, as well, so we can’t completely remove it from the body.”10
As such, the researchers had to find a dose of mannose sufficient to block glucose such that it slowed tumor growth, but allowed normal tissues to remain unaffected. “This is early research, but it is hoped that finding this perfect balance means that, in the future, mannose could be given to cancer patients to enhance chemotherapy without damaging their overall health,” Ryan stated.11
Beyond the cancers mentioned above, the team exposed cells from other types of cancer — including bone, bowel, leukemia and ovarian — to mannose. Some of the cancer cells responded well to mannose while others did not. About this, one source noted, “The anticancer potential of mannose appeared to depend on whether an enzyme that breaks down the sugar was present in cells.”12
Should You Use Cranberry Juice to Treat UTIs or Cancer?
Very likely you’ve been told that drinking cranberry juice can soothe cystitis and UTIs. Now, the current research seems to suggest it can be used to treat cancer. As such, you may be thinking about loading up on cranberry juice, which I do not recommend.
First, while the use of mannose to treat bladder and urinary tract issues is well founded, I advise you to avoid cranberry juice as a medical treatment. That’s because you’d have to drink a lot of juice, which is often laden with toxic amounts of sugar.
For those conditions, consult your medical practitioner to ensure an accurate diagnosis and then inquire about the possible use of a mannose-containing supplement. Second, with respect to cancer treatment and mannose, keep in mind this research is preliminary and has yet to be tested on humans.
With respect to that, Ryan commented, “Our next step is investigating why [the] treatment only works in some cells, so that we can [determine] which patients might benefit the most from this approach.” He expressed his desire to see clinical trials begin on mannose “as soon as possible to determine its true potential as a new cancer therapy.”
Martin Ledwick, Cancer Research UK’s head information nurse, joined Ryan in cautioning cancer patients to resist the temptation to self-medicate with mannose. Ledwick said:
“Although these results are very promising for the future of some cancer treatments, this is very early research and has not yet been tested in humans.
Patients should not self-prescribe mannose as there is a real risk of negative side effects that haven’t been tested for yet. It’s important to consult with a doctor before drastically changing your diet or taking new supplements.”
The bottom line is it’s difficult to regulate your body’s glucose levels in a healthy manner through self-experimentation. This is particularly the case if you are dealing with a serious illness like cancer or diabetes. While mannose may be a useful complementary treatment, I also encourage you to:
Eat a healthy, whole food diet, which implies avoiding processed foods and sugar, especially soda and sweets
Exercise regularly
Get at least seven to nine hours of high-quality sleep every night
Reach out for or continue receiving treatment from professional health care practitioners who are familiar with your condition and experienced in natural approaches
What Is Mannose and How Does It Work?
As mentioned, mannose is a monosaccharide found in cranberries and other fruits, including apples, blueberries, oranges and peaches. It also resides in vegetables like broccoli, cabbage and green beans.
About this simple sugar, The Clinical Advisor says, “In addition, d-mannose occurs naturally in some cells in the human body and is thought to be a prebiotic, because consumption of d-mannose stimulates and fosters the growth of good bacteria in the digestive tract.”
Beyond its presence in whole foods and your body, mannose also commonly appears in supplement form under the name D-mannose. Although mannose is chemically considered a simple sugar, structurally, it is similar to glucose.
That said, it is absorbed more slowly in your gastrointestinal tract than glucose, which accounts for its lower glycemic index. With respect to this aspect of mannose, The Clinical Advisor notes:
“Compared with actual glucose, which is readily absorbed and has a glycemic index of 100, mannose must first be converted into fructose and then into glucose, significantly blunting the insulin response and reducing its impact on blood sugar levels.
After mannose is absorbed by the gut, it is not stored in the liver like glucose, but is filtered out of the body directly by the kidneys.”
For the experiments in which mannose was given to lab mice afflicted by cancers such as bone, bowel, leukemia and ovarian, mannose was shown to more readily disrupt cells that had lower levels of an enzyme called phosphomannose isomerase (PMI). About the impact of PMI, the study authors stated:
“Cells with low levels of PMI are sensitive to mannose, whereas cells with high levels are resistant. … PMI levels also vary greatly between different patients and different tumor types, indicating that PMI levels could be used as a biomarker to direct the successful administration of mannose. …
[T]he administration of mannose could be a simple, safe and selective therapy in the treatment of cancer, and could be applicable to multiple tumor types.”
Research Validates Mannose for Treating Rare Disease CDG and UTIs
D-mannose has been shown to help in the treatment of a rare disease called carbohydrate-deficient glycoprotein syndrome type 1b (CDG 1b). This condition is passed down through families and is characterized by liver and digestive problems associated with hyperinsulinism and inconstant thrombosis. Beyond that, the condition causes your body’s blood coagulation factors to be decreased.
About CDG 1b and mannose, authors of a 2009 study commented, “In our experience, mannose given orally at least four times per day not only transformed lethal CDG 1b into a treatable disease, but also improved the general condition and digestive symptoms of all reported patients but one.”17
As mentioned, D-mannose is commonly used to prevent and treat UTIs, which are usually caused when E. coli bacteria is transferred from your intestinal tract to your urinary tract. D-mannose is great for UTIs because it attaches to the E. coli bacteria, causing them to stick to each other instead of clinging to the walls of your urinary tract.
Under those conditions, the harmful bacteria can be eliminated from your body during urination. Given the increasing instances of antibiotic resistance, natural remedies for UTIs are imperative.
A 2014 study published in the journal World Journal of Urology found D-mannose powder to be as effective as an antibiotic in treating recurrent UTIs in women. A total of 308 women were divided into three groups:18
The first group received 2 grams (g) of D-mannose powder mixed in water daily for six months
A second group was given 50 milligrams (mg) of the antibiotic Nitrofurantoin daily
The third group was a control group and received no treatment
Of the 98 patients experiencing a recurrent UTI, just 15 percent of them consumed D-mannose, whereas 20 percent took the antibiotic and 61 percent received no treatment.
With respect to the outcomes, the study authors said, “D-mannose powder significantly reduced the risk of recurrent UTI, which was no different from [the] Nitrofurantoin group. More studies will be needed to validate the results … but initial findings show that D-mannose may be useful for UTI prevention.”19
If you have been plagued by recurrent UTIs or bladder inflammation, particularly if you are concerned about antibiotic resistance, now may be the time to talk to your health care practitioner about trying D-mannose. It is generally quite effective for up to 90 percent of UTI cases.
The only exception would be UTIs caused by a bacterium other than E. coli; in that case, you’d be better served to ask your doctor about supplements known to disrupt biofilms.20
Mannose Contributes to the Healing Properties of Aloe Vera
While you probably know aloe vera is beneficial for soothing burns, improving wound healing and inhibiting inflammation, you may not be aware that the major sugar in aloe vera is mannose. In a 1994 study, lab mice receiving 300 mg/kilogram (kg) of mannose-6-phosphate showed improved wound healing compared to those treated with saline controls.
The researchers noted, “This dose also had anti-inflammatory activity.”1` Authors of a 2004 study added, “The clear pulp, also known as inner gel, of [the] Aloe vera L. leaf is widely used in various medical, cosmetic and nutraceutical applications. Many beneficial effects of this plant have been attributed to the polysaccharides present in the pulp.”22
Another source states, “High concentrations of mannan saccharides are available in the gel of aloe plants. Laboratory studies show the effects of glucomannan saccharides signals as they activate the immune response through increased expressions of interleukin-1, interleukin-6 and tumor necrosis factor.”
Cautions About Taking Mannose
While mannose is thought to be well tolerated in most people, I do not recommend supplementing with it if you are pregnant or breastfeeding due to the lack of research validating its safe use. That said, pregnant and breastfeeding moms should be fine consuming mannose-containing foods, assuming it is done in moderation. 
The side effects associated with mannose may include bloating and loose stools. Beyond that, since mannose could make it harder to regulate your blood sugar if you have diabetes, use caution when taking D-mannose supplements if you are diabetic.
While the news about mannose as a potential cancer fighter is encouraging, more research, including clinical trials, is needed to validate its effectiveness. For your safety, always consult a medical professional before taking a new supplement or changing the dosing associated with any of your existing supplements.
from Articles http://articles.mercola.com/sites/articles/archive/2018/12/10/mannose-health-benefits.aspx source https://niapurenaturecom.tumblr.com/post/180977158516
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