#stem cell journal list

[mustafaakindele]

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[nursingwriter]

Baldness and thinning hair are common and the ultimate fate of almost all men and women as they age. In fact, hair loss is genetic in origin, and as we come to a greater understanding of the biology and genetics of hair loss, we are beginning to find novel solutions to this age-old "problem" of the human condition. We have come a long way from the treatments for hair loss in ancient Egypt, which used a mixture of crocodile fat and hippopotamus dung to combat baldness. Another ancient cure for baldness included eating fried leeches. Men have been attempting to treat their hair loss for over 5000 years, beginning in approximately 3500 BC, when a list of treatments was passed on from generation to generation and incorporated into the medical libraries of Egyptian healers. In 1553 BC, the Ebers Papyrus, discovered in Luxor, Egypt, suggested a baldness prescription of iron, red lead, onions, alabaster, and honey which was to be swallowed, after first reciting a magical invocation to the sun god. In 420 BC, the ancient Grek Hippocrates, formulated an anti-hair loss mixture of opium, horseradish, pigeon droppings, beetroot, and various spices applied to the scalp. Hippocrates himself eventually became so bald that extreme cases of baldness became known as "Hippocratic baldness." He noted, however, that eunuchs never became bald -- a fact that was insightful and has been explained by modern baldness research. The hair follicle is like a factory where both hair and its color are produced. There are about 100,000 hairs on the human scalp, and we can lose as many as 100 daily. These hairs, once they actually leave the hair canal, are biologically "dead" and can be cut, dyed, curled and straightened. One line of exciting new research involves stem cell research, which is also giving hope to people with serious problems like cancer, Parkinson's disease and spinal cord injury. Adult stem cells -- which are located in the hair follicle -- are the source of scientific excitement. According to a January 7, 2000 article in the journal Cell, if stem cells can be channeled into specific "differentiation programs' they can be used for many therapies. "Among these are the generation of dermal papilla or hair follicle stem cells for treatment of baldness." One of the most interesting findings in the last few years is the discovery of a gene linked to hair growth and loss. According to a 1998 study reported in Science, a gene called "hairless" is linked to a severe form of inherited baldness and may be the gene that directs the entire human hair cycle. Principle investigator Angela M. Christiano, Herbert Irving Assistant Professor of Dermatology, hailed the discovery of this gene as the beginning of anew era "that gives us endless possibilities that may allow us to effectively treat hair loss and possibly baldness within the next five years. It is now within our reach to design ways to grow hair, remove hair, even dye hair genetically and this can all be accomplished topically, reducing possible side effects." How did the researchers discover this gene? The story is fascinating. There are a number of families affected by a rare genetic form of balding that is common in a village in Pakistan. It is called alopecia universalis. It causes hair loss over the entire body. This allowed researchers to pinpoint the gene. There are several forms of alopecia, or hair loss, in human hair growth. The most common type is known as androgenetic alopecia, or male pattern baldness. It affects around 80% of men -- and by age 60, two thirds of men already suffer hairloss. That represents 40 million men in the U.S. The current theory about this type of baldness is that as a male ages his hair follicles start to produce an enzyme called 5-alpha reductase, which converts testosterone into a form called dihydrotestosterone or DHT. DHT apparently causes hair follicles to spend less time growing and more time resting. The first stage of a hair's life cycle is the growing stage, which lasts two to five years. At any one time about ninety percent of hair follicles are in this stage, and they produce a tough protein, keratin, which helps the hair become thick. If these cells are not working at full capacity, they produce a "vellus hair" -- the peach fuzz of men who are going bald. Follicles influenced by DHT tend to produce vellus hair. They may also shrink and become constricted. Interestingly, other specialized cells in the follicle produce "melanin," which gives hair its color. Women can also suffer from baldness, but it is a generalized thinning of hair, not the pattern men get. Usually women's hair doesn't "recede." Even so, about 15% of all women are eventually afflicted with hair loss that is depressingly obvious. In addition, a type of hair loss known as "telogen effluvium" can afflict women. It is characterized by many hairs entering the telogen stage at once -- and it is a condition often brought about by rash dieting, chronic physical or emotional stress, severe illness, or post-pregnancy hormone changes. Once the woman recovers from the stress on her body, her hair will begin growing again, but to recover that lost hair can take up to a year. A strange form of hair loss is one that is self-induced: trichotillomania and traction alopecia. In these odd conditions, people pull and twist their hair. Sometimes drugs used for obsessive-compulsive disorder can help this condition. In addition, many common drugs can cause hair loss. Chemotherapy patients tend to lose their hair, because the drugs not only stop cancer cells from dividing, they stop hair follicles from growing hair. Other drugs that can induce hair loss include: clofibrate and gemfiborzil (cholesterol lowering drugs); levodopa (Parkinson's medication), ulcer drugs like Tagamet, Zantac and Pepcid; anticoagulants like Comouran and Heparin, beta blocker drugs for high blood pressure and several other drugs. Another form of hair loss, alopecia areata is a relatively common disease affecting 2.5 million people in America, or 1.7% of the U.S. population. It is thought to be an autoimmune disorder, that may be triggered by stress. Princess Stephanie, Grace Kelley's daughter, suffered from temporary alopecia areata during a stressful period. It may show up in childhood, and it takes three forms: alopecia areata (loss on the scalp); alopecia totalis (total loss on the scalp) and alopecia universalis (all scalp and body hair). In more than 80% alopecia areata will eventually go away on its own, especially if it occurs after puberty. Because it may be an autoimmune disorder, both topical and oral steroids are sometimes given to treat it. For more severe forms, stronger immunosuppressive drugs may be used. Male pattern baldness is not just a matter of hair loss. It has also been linked to a higher incidence of heart disease. A Harvard study examined the link between hair loss and heart conditions, and found that men with extensive baldness had the greatest risk of heart disease -- 36% higher than normal. On the other hand, according to JoAnn Manson, a professor at Harvard Medical School, those with mild frontal hair loss or a receding hairline had no significant increased risk. Several drugs are currently available to help male pattern baldness. Rogaine (monixidil) and Propecia (finasteride) are both approed by the FDA. They were drugs originally used for serious illness. Rogaine was used for high blood pressure, and finasteride for both prostate cancer and benign prostate enlargement. Rogains is sprayed or massaged into thinning areas of the scalp. Its' though to dilate the blood vessels and increase circulation, perhaps stimulate the hair follicles to grow back to their original size, or perhaps keep the follicles longer in the growing stage. Propecia is taken orally and helps slow down the conversion of testosterone into DHT. These drugs are somewhat effective in regrowing hair on the crown of the head, but don't seem to help a receding hairline. Rogaine can also be used by women. Another treatment for baldness is hair transplant surgery. It's a procedure that can cost as much as $20,000, though often the price is lower. The current state-of -- the art technique is known as follicular unit micrografts. Many scalp hair follicles naturally grow in tight bundles of two or three hairs. With old style micrografting, these bundles of hair follicles were typically cut up to create one or two hair micrografts, in order to remove as much excess skin tissue as possible. The problem was that all this cutting caused the loss of a percentage of donor hairs. Now, with advanced equipment such as back-lit stereo microscopes, the naturally occurring hair follicle bundles are left intact, while still trimming away unwanted skin tissue. The end result is a more natural appearance, with minimal loss of scarce donor hairs. The future for baldness is a promising one: stem cell treatments and gene therapy will probably allow us all to choose our hair color and thickness one day. If we can change hair follicle sensitivity to DHT, we can prevent male hair loss in the first place. With cloning we could create an unlimited supply of "permanent" hairs to replace those we lose. Eventually we will be able to grow entire follicles from a few cells cultured in a test tube. This will allow an unlimited supply of thick growing hair for everyone. Bibliography Bruning, Nancy Paul. What You Can Do About Chronic Hair Loss (The Dell Medical Library) Dell, 1993. Jacobs, Sheila. The Big Fall: Living With Hair Loss Next Century Books, 1992 Kobren, Spencer David; Eisman, Diane B; Eisman, Eugene H. The Bald Truth: The First Complete Guide to Preventing and Treating Hair Loss, Pocket Books. 2000 Kobren, Spencer David; Christiano, Angela. The Truth About Women's Hair Loss: What Really Works for Treating and Preventing Thinning Hair. Mcgraw Hill, 2000. Kuntzman, Gersh. Hair! Mankind's Historic Quest to End Baldness. Digital Downloadable Book, 2001. Pinski, Bernard James. Hair Replacement: How to Reduce the Effects of Male Pattern Baldness (Doctor to Patient Series) JB Media International, 1991. Segrave, Kerry. Baldness: A Social History. McFarland & Co. 1996 Tse, David. Hair Loss Treatment Almanac 1998. TSE Publishing. 1998 https://www.paperdue.com/customer/paper/baldness-and-thinning-hair-are-common-and-140025#:~:text=Logout-,Baldnessandthinninghairarecommonand,-Length6pages Read the full article

[alvavi]

Can Your Diet Solve Colon Issues? The Surprising Link Between Food and Gut Health

The best colon cleanser is here

A Gut Feeling You Can’t Ignore Imagine a world where your stomach doesn’t dictate your daily plans — no sudden cramps, bloating, or urgent trips to the bathroom. For millions worldwide, this is a distant dream. Colon issues, from irritable bowel syndrome (IBS) to chronic inflammation, disrupt lives silently yet persistently. But what if the key to unlocking digestive harmony lies not in a pharmacy, but on your plate? Recent scientific breakthroughs reveal that the food we eat isn’t just fuel — it’s a powerful communicator with our gut. Let’s dive into the fascinating connection between diet and colon health, backed by cutting-edge research, and discover how simple dietary shifts can transform your gut — and your life.

Spread awareness with your clothes here

1. Understanding Common Colon Issues: Beyond Occasional Discomfort

Colon problems are more prevalent than you might think. The World Gastroenterology Organisation reports that 1 in 5 adults globally suffer from functional gastrointestinal disorders, with IBS, inflammatory bowel disease (IBD), and chronic constipation leading the list. These conditions often stem from a mix of genetic, environmental, and lifestyle factors, but diet plays a starring role.

Irritable Bowel Syndrome (IBS): Characterized by cramping, diarrhea, and constipation, IBS is linked to gut-brain axis imbalances and food sensitivities. A 2021 study in Gut journal found that 70% of IBS patients reported symptom improvement after dietary modifications.

Inflammatory Bowel Disease (IBD): Conditions like Crohn’s disease and ulcerative colitis involve chronic inflammation. Research in Nature Reviews Gastroenterology & Hepatology highlights that diets high in processed foods and low in fiber exacerbate inflammation.

Small Intestinal Bacterial Overgrowth (SIBO): This occurs when gut bacteria become imbalanced, often triggered by high-sugar diets or prolonged antibiotic use.

The best colon cleanser is here

2. The Fiber Factor: Why Your Colon Craves Roughage

Fiber isn’t just a buzzword — it’s the colon’s best friend. This indigestible carbohydrate acts as a prebiotic, feeding beneficial gut bacteria and promoting regular bowel movements. Here’s how it works:

Soluble vs. Insoluble Fiber: Soluble fiber (found in oats, apples, and beans) absorbs water to soften stools, while insoluble fiber (in whole grains and vegetables) adds bulk. A 2020 meta-analysis in The Lancet linked high-fiber diets to a 30% lower risk of colorectal cancer .

The Microbiome Connection: Fiber-rich diets boost Bifidobacteria and Lactobacillus strains, which produce short-chain fatty acids (SCFAs) like butyrate. These SCFAs repair gut lining and reduce inflammation, as shown in a Cell Host & Microbe study.

Pro Tip: Gradually increase fiber intake to avoid bloating, and pair it with ample water.

3. Foods That Wreak Havoc: Common Culprits Behind Colon Distress

Not all foods are created equal. Certain ingredients can inflame the gut, trigger spasms, or feed harmful bacteria:

Processed Foods: Emulsifiers in packaged snacks disrupt gut bacteria, as revealed in a 2022 Science study.

Dairy and Lactose: Up to 65% of adults struggle to digest lactose, per the NIH, leading to gas and diarrhea.

High-FODMAP Foods: Onions, garlic, and legumes contain fermentable carbs that can worsen IBS symptoms.

Alcohol and Caffeine: These irritate the gut lining, increasing acid production and dehydration.

The best colon cleanser is here

4. Healing Foods: Nourish Your Gut, Nourish Your Life

The right foods can rebuild your gut’s ecosystem. Here’s what to prioritize:

Fermented Foods: Yogurt, kimchi, and sauerkraut deliver probiotics to restore bacterial balance. A 2021 Stanford study found that fermented foods increase microbiome diversity by 40% .

Omega-3 Fatty Acids: Found in salmon and walnuts, these reduce inflammation.

Herbs and Spices: Turmeric’s curcumin and ginger’s anti-inflammatory properties soothe the gut lining.

Hydration: Water keeps stools soft and aids fiber function.

Spread awareness with your clothes here

5. The Science of Balance: Creating a Gut-Friendly Diet Plan

A healthy colon thrives on diversity and moderation. Consider these strategies:

Low-FODMAP Diet: Temporarily eliminate trigger carbs, then reintroduce them under guidance.

Mediterranean Diet: Rich in fiber, healthy fats, and antioxidants, this diet is linked to lower IBD risk.

Mindful Eating: Chew thoroughly and eat slowly to aid digestion.

The best colon cleanser is here

Conclusion: Your Fork Is Your Best Medicine

The road to colon health isn’t found in a pill bottle — it’s in your kitchen. By embracing fiber-rich, anti-inflammatory foods and avoiding gut disruptors, you can transform your digestive health. As the ancient Greek physician Hippocrates wisely said, “All disease begins in the gut.” Today, science confirms that healing begins there too. Start small: swap that sugary snack for a handful of almonds, or add a probiotic-rich side to dinner. Your colon — and your future self — will thank you.

Spread awareness with your clothes here

[naresh12-08-2002]

Exploring the Pinnacle of Scientific Research: Best Science Journals of 2023

Introduction:

Science is a dynamic field that constantly evolves through research and discovery. Researchers, academics, and enthusiasts alike rely on best science journals as valuable repositories of knowledge. These journals serve as gateways to the latest breakthroughs, critical reviews, and cutting-edge theories. However, with a multitude of science journals available, it can be challenging to pinpoint the best ones. In this article, we will delve into the world of scientific publishing and present a list of some of the best science journals in 2023.

 Nature:

Nature is one of the most prestigious and widely recognized best science journals in the world. Covering a broad spectrum of scientific disciplines, including biology, physics, chemistry, and more, Nature has been at the forefront of groundbreaking research for decades. The journal consistently publishes top-tier studies, reviews, and commentaries, making it a must-read for scientists and researchers.

 Science:

Science, published by the American Association for the Advancement of Science (AAAS), is another influential journal that spans various scientific fields. It boasts a reputation for publishing high-impact research and comprehensive reviews. Science also features news and commentary on scientific developments, making it a comprehensive resource for staying updated on the latest trends in the world of science.

The New England Journal of Medicine:

For those interested in medical and healthcare research, The New England Journal of Medicine (NEJM) is a beacon of excellence. Renowned for its rigorous peer-review process and commitment to publishing groundbreaking medical research, NEJM is a vital resource for healthcare professionals, researchers, and policymakers alike.

 Cell:

Cell is a leading journal in the field of cell biology and molecular biology. It is part of the Cell Press family of best science journals which also includes Cell Stem Cell, Cell Reports, and others. Cell publishes research articles, reviews, and commentaries that delve deep into cellular processes, genetics, and genomics. Its comprehensive coverage and impactful research have earned it a prominent place in the scientific community.

 The Lancet:

The Lancet is one of the world's oldest and most respected medical journals. It covers a wide range of medical disciplines and is particularly well-known for its global health research and policy analysis. Researchers and healthcare professionals rely on The Lancet for authoritative studies and insights into critical healthcare issues.

 Science Advances:

Science Advances is an open-access journal published by the American Association for the Advancement of Science (AAAS). As an open-access platform, it offers free access to a wide range of scientific content, making it an inclusive resource for researchers and the public. The journal covers diverse scientific disciplines, from biology to social sciences, and emphasizes high-quality research and innovation.

 Proceedings of the National Academy of Sciences (PNAS)

PNAS is a prestigious multidisciplinary journal that publishes research across the natural, social, and applied sciences. It is known for its commitment to publishing research that addresses significant scientific questions. PNAS is a go-to source for cutting-edge research papers that span a wide range of disciplines.

Conclusion:

Scientific journals play an integral role in disseminating knowledge and advancing our understanding of the world. The best science journals of 2023, including Nature, Science, The New England Journal of Medicine, Cell, The Lancet, Science Advances, and PNAS, continue to shape the scientific landscape with their exceptional research articles, reviews, and commentary. Whether you are a researcher, student, or simply curious about the latest developments in science, these journals provide valuable insights into the ever-evolving world of scientific discovery.

27 Old Gloucester Street

London, England

#Research #papers #publish

[caesarsaladinn]

1. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. N ENGL J MED; APR 2013.

2. Predictive Validity of a Medication Adherence Measure in an Outpatient Setting. The Journal of Clinical Hypertension. May 2, 2008. 

3. MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecologic Oncology. June 25, 2008.

4. Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. LANCET; FEB 28 1998.

5. Visfatin: A protein secreted by visceral fat that mimics the effects of insulin. SCIENCE; JAN 2005. 

6. An enhanced transient expression system in plants based on suppression of gene silencing by the p19 protein of tomato bushy stunt virus. PLANT J; MAR 2003. 

7. Lysyl oxidase is essential for hypoxia-induced metastasis. NATURE; APR 2006. 

8.TREEFINDER: a powerful graphical analysis environment for molecular phylogenetics. BMC EVOL BIOL; JUN 2004. 

9. Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. LANCET, NOV 2011. 

10. Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells. BLOOD; NOV 2001. 

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an interesting list! they mostly seem to be fake breakthroughs on intractable, multivariate problems (nutrition, heart disease, cancer, diabetes, autism). number four is, of course, the Wakefield autism/vaccine paper. I think the recently retracted Alzheimer's paper on amyloid plaques has enough citations to be in the top 10, so this list is a little out of date.

[xtruss]

The Longest-Living Animals on Earth

Tortoises Fon't Even Make the Top 10 Longest-Living Animals.

— By Patrick Pester | Live Science

The animal kingdom boasts some incredibly long lifespans that far exceed the average human's. While humans may have an "absolute limit" of 150 years, this is just a blink of an eye compared with the centuries and millennia that some animals live through; and some animals can even stop or reverse the aging process altogether.

Although there are very long-living land animals (the oldest tortoise, for example, is nearly 190 years old), none of them make this list — the true age champions all live in water. From old to oldest, here are 10 of the longest-living animals in the world today.

1. BOWHEAD WHALE: POTENTIALLY 200+ YEARS OLD

Aerial view of a bowhead whale in the Sea of Okhotsk in Russia. (Image credit: by wildestanimal via Getty Images)

Bowhead whales (Balaena mysticetus) are the longest living mammals. The Arctic and subarctic whales' exact lifespan is unknown but stone harpoon tips found in some harvested individuals prove that they comfortably live over 100 years, and may live more than 200 years, according to the National Oceanic and Atmospheric Administration (NOAA).

The whales have mutations in a gene called ERCC1, which is involved with repairing damaged DNA, that may help protect the whales from cancer, a potential cause of death. Furthermore, another gene, called PCNA, has a section that has been duplicated. This gene is involved in cell growth and repair, and the duplication could slow aging, Live Science previously reported.

2. ROUGHEYE ROCKFISH: 200+ YEARS OLD

A vermilion rockfish swimming off the coast of California. This is a relative of the long-lived rougheye rockfish but not the same species. (Image credit: Brent Durand via Getty Images)

Rougheye rockfish (Sebastes aleutianus) are one of the longest living fish and have a maximum lifespan of at least 205 years, according to the Washington Department of Fish and Wildlife. These pink or brownish fish live in the Pacific Ocean from California to Japan. They grow up to 38 inches (97 centimeters) long and eat other animals such as shrimp and smaller fish, according to the Committee on the Status of Endangered Wildlife in Canada (COSEWIC), an independent advisory panel that assesses the status of species threatened with extinction in Canada.

3. FRESHWATER PEARL MUSSEL: 250+ YEARS OLD

Freshwater mussels from the Margaritifera genus. (Image credit: Irfan M Nur/Shutterstock.com)

Freshwater pearl mussels (Margaritifera margaritifera) are bivalves that filter particles of food from the water. They mainly live in rivers and streams and can be found in Europe and North America, including the U.S. and Canada. The oldest known freshwater pearl mussel was 280 years old, according to the World Wildlife Fund (WWF). These invertebrates have long lifespans thanks to their low metabolism.

Freshwater pearl mussels are an endangered species. Their population is declining due to a variety of human-related factors, including damage and changes to the river habitats they depend on, according to the International Union for Conservation of Nature (IUCN).

4. GREENLAND SHARK: 272+ YEARS OLD

Greenland shark swimming with isolated on black background. (Image credit: dotted zebra / Alamy Stock Photo)

Greenland sharks (Somniosus microcephalus) live deep in the Arctic and North Atlantic oceans. They can grow to be 24 feet (7.3 meters) long and have a diet that includes a variety of other animals, including fish and marine mammals such as seals, according to the St. Lawrence Shark Observatory in Canada.

A 2016 study of Greenland shark eye tissue, published in the journal Science, estimated that these sharks can have a maximum lifespan of at least 272 years. The biggest shark in that study was estimated to be about 392 years old, and the researchers suggested that the sharks could possibly have been as much as 512 years old, Live Science previously reported. The age estimates came with a degree of uncertainty, but even the lowest estimate of 272 years still makes these sharks the longest living vertebrates on Earth.

5. TUBEWORM: 300+ YEARS OLD

Tubeworms on the ocean floor. (Image credit: Ralph White via Getty Images)

Tubeworms are invertebrates that have long lifespans in the cold, stable environment of the deep sea. A 2017 study published in the journal The Science of Nature found that Escarpia laminata, a species of tubeworm living on the ocean floor in the Gulf of Mexico, regularly lives up to 200 years, and some specimens survive for more than 300 years. Tubeworms have a low death rate with few natural threats, such as a lack of predators, which has helped them evolve to have such long lifespans.

6. OCEAN QUAHOG CLAM: 500+ YEARS OLD

A quahog clam on a beach in Cape Cod in Massachusetts. (Image credit: Gabe Dubois/Shutterstock.com)

Ocean quahog clams (Arctica islandica) inhabit the North Atlantic Ocean. This saltwater species can live even longer than the other bivalve in this list, the freshwater pearl mussels. One ocean quahog clam found off the coast of Iceland in 2006 was 507 years old, according to National Museum Wales in the U.K. The ancient clam was nicknamed Ming as it was born in 1499 when the Ming Dynasty ruled China (from 1368 to 1644).

7. BLACK CORAL: 4,000+ YEARS OLD

Black coral bushes on a reef. (Image credit: Mike Workman/Shutterstock.com)

Corals look like colorful, underwater rocks and plants, but they are actually made up of the exoskeletons of invertebrates called polyps. These polyps continually multiply and replace themselves by creating a genetically identical copy, which over time causes the coral exoskeleton structure to grow bigger and bigger. Corals are therefore made up of multiple identical organisms rather than being a single organism, like Greenland sharks or ocean quahog clams, so a coral's lifespan is more of a team effort.

Corals can live for hundreds of years or more, but deep-water black corals (Leiopathes sp.) are among the longest-living corals. Black coral specimens found off the coast of Hawaii have been measured to be 4,265 years old, Live Science previously reported.

8. GLASS SPONGE: 10,000+ YEARS OLD

An illustration of sponges, including Monorhaphis chuni (labeled 2 on the left). (Image credit: History and Art Collection/Alamy Stock Photo)

Sponges are made up of colonies of animals, similar to corals, and can also live for thousands of years. Glass sponges are among the longest living sponges on Earth. Members of this group are often found in the deep ocean and have skeletons that resemble glass, hence their name, according to NOAA. A 2012 study published in the journal Chemical Geology estimated that a glass sponge belonging to the species Monorhaphis chuni was about 11,000 years old. Other sponge species may be able to live even longer.

9. TURRITOPSIS DOHRNII: POTENTIALLY IMMORTAL

A Turritopsis immortal jellyfish off the coast of Palm Beach in Florida. (Image credit: Blue Planet Archive/Alamy Stock Photo)

Turritopsis dohrnii are called immortal jellyfish because they can potentially live forever. Jellyfish start life as larvae, before establishing themselves on the seafloor and transforming into polyps. These polyps then produce free-swimming medusas, or jellyfish. Mature Turritopsis dohrnii are special in that they can turn back into polyps if they are physically damaged or starving, according to the American Museum of Natural History, and then later return to their jellyfish state.

The jellyfish, which are native to the Mediterranean Sea, can repeat this feat of reversing their life cycle multiple times and therefore may never die of old age under the right conditions, according to the Natural History Museum in London. Turritopsis dohrnii are tiny — less than 0.2 inches (4.5 millimeters) across — and are eaten by other animals such as fish or may die by other means, thus preventing them from actually achieving immortality.

10. HYDRA: ALSO POTENTIALLY IMMORTAL

A photo of a Hydra, the small invertebrates that could be immortal. (Image credit: Choksawatdikorn/Shutterstock.com)

Hydra is a group of small invertebrates with soft bodies that look a bit like jellyfish. Like Turritopsis dohrnii, Hydras also have the potential to live forever. Hydras don't show signs of deteriorating with age, Live Science previously reported. These invertebrates are largely made up of stem cells, which continually regenerate through duplication or cloning. Hydras don't live forever under natural conditions because of threats like predators and disease, but without these external threats, they could be immortal.

[dofuuu]

What is regenerative medicine?

To answer this, we have to first know what regeneration itself means for our bodies: it’s the restoration of normal function and structure of tissues/organs, like how a hydra plant is able to regenerate its entire form from a small piece of its body and how a newt is able to regrow amputated limbs.

Although we aren’t able to regrow entire limbs, human tissues are still able to experience regeneration if a problem arises within them; not only does treatment of diseases involving regeneration aim to restore damaged tissues through for example, blunt trauma, regenerative medicine may also be able to tackle diseases or abnormalities that an individual is born with, such as thalassaemia (a blood disorder which causes anemia), or if a person is born without corneas.

A major component of regenerative medicine is the involvement of stem cells– after all, stem cells are able to divide into cells that can either remain as stem cells or develop as cells of specific tissues with particular functions (through a process called ‘differentiation’)! 

There are actually variety of different stem cell types found throughout our bodies, and there are some are more capable of tissue regeneration than others!

Hematopoietic stem cells are just one example of a type of stem cell that you have in your body right now: these cells are found within the tightly-regulated environment of your bone marrow and they’re responsible for both the generation and regeneration of all your white and red blood cells as well as platelet cells. Hematopoietic stem cells are also found within the umbilical cords. 

One way that hematopoietic stem cells have been used to treat patients is through gene therapy: the stem cells are removed from the patient with the purpose of altering the cell to express or inhibit certain genes, then reintroduced back into the patient, and the use of gene therapy has been involved in treating various immunodeficiency-related diseases such as SCID. Additionally, stem cell transplantations of hematopoietic stem cells have been performed successfully on cancer patients: where the patient receives either their own bone marrow or a compatible donor’s following chemotherapy and irradiation to help improve patient survival. 

Because compatible donors are very often needed for these stem cell transplantations, it’s important to note that donors must match the HLA (Human Leukocyte Antigen) type of a patient for this potentially life-saving procedure to occur; HLA type is determined by cheek swab collection, so it isn’t very difficult to determine if you are a good match for a patient in need of a hematopoietic stem cell transplant. Speaking of which, if you’re interested in becoming a potential donor, you could register as a donor today to help save lives!

If you’re a Canadian who might be interested in becoming a registry member, here is a link to learn more:

https://www.blood.ca/en/stem-cells?utm_source=onematch&utm_medium=redirect&utm_campaign=onematch

If you’re an American who’s interested, here’s a link for more information as well:

https://join.bethematch.org/s/landing?language=en_US&ref=sidenavjoin

Outside of those two countries, here is an exhaustive list of various bone marrow registries found worldwide:

 https://share.wmda.info/display/WMDAREG/WO-1361#/

There are other types of stem cell types also have uses in regenerative medicine, which include mesenchymal stem cells that may be used in cartilage repair and regeneration as well as well as providing therapeutic effects for those with autoimmune diseases. 

Alongside gene therapy and stem cell transplantation, cell reprogramming is yet another approach to regenerative medicine, where already-developed cells from your body can be reprogrammed to express certain stem cell-related genes to induce pluripotency: the ability for a cell to generate every cell type within an organism. These stem cells are referred to as induced pluripotent stem cells.

However, in order to use stem cells, we have to first be able to understand them: what differing characteristics they have, how they behave and interact with certain environments. Therefore, it is very important to acknowledge that the use of stem cells in medicine has tremendous therapeutic potential. 

Research involving stem cells and how they can be used to treat patients that have various diseases and conditions is very much still ongoing, yet there still exists challenges to overcome [my other post here will address these concerns]

All in all, regenerative medicine encompasses gene therapy, stem cell transplantation, tissue engineering (wherein cells are combined with scaffolding to regenerate tissues), and cell reprogramming– all of which have a solid place in future research studies and a great potential for future treatment of diseases.

Thank you very much for taking the time out of your day to read about regenerative medicine!!

References:

Porter, L. (2020). Overview of regeneration [PPT slides]. Retrieved from https://blackboard.uwindsor.ca/bbcswebdav/pid-1202671-dt-content-rid-13745597_1/xid-13745597_1

Mason, C. & Dunnill, P. (2007). A brief definition of regenerative medicine. Regenerative Medicine, 3(1). np. doi:10.2217/17460751.3.1.1

Porter, L. (2020). Hematopoiesis [PPT slides]. Retrieved from https://blackboard.uwindsor.ca/bbcswebdav/pid-1228944-dt-content-rid-14541532_1/xid-14541532_1

Goldberg, A., Mitchell, K., Soans, J., Kim, L., & Zaidi, R. (2017). The use of mesenchymal stem cells for cartilage repair and regeneration: a systematic review. Journal of Orthopaedic Surgery and Research, 12(39). np. doi:10.1186/s13018-017-0534-y

Robinton, D.A., & Daley, G. (2012). The promise of induced pluripotent stem cells in research and therapy. Nature, 481(7381). 295-305. doi:10.1038/nature10761

[polsref]

[Image descriptions:

Slide 1: What we know (and don't) about COVID-19's effect on the immune system. Presented by the Yale School of Public Health.

Slide 2: Lasting impact. Growing research shows infection with SARS-CoV-2 can created lasting differences in some people's immune systems. (Sources: CDC, Memorial Sloan Kettering Library.)

Slide 3: This looks like...

Altered immune system cells. Severe cases of COVID-19 can change the parent stem cells that generate immune cells. these altered stem cells create cells that are more inflammatory.

Viral reservoirs and fragments. proteins and fragments that have been found in people with Long COVID can set off a continuing immune response and amplify inflammation.

Immune dysregulation and chronic inflammation. Dysregulation is when some immune cells are working hard, and others are exhausted. How long it can last is unknown.

Triggered autoimmune conditions, blood clots, and latent viruses. COVID-19 infections can trigger autoantibodies that lead to autoimmune disorders.

(Sources: NIH, Memorial Sloan Kettering Library, PNAS, Nature Immunology, Nature, Cell, eClinical Medicine.)

Slide 4: 5 to 20% of people develop lingering symptoms or new health conditions after infection, called Long COVID. As of the CDC's latest count in March 2024, 30% of all American adults who've had COVID have experienced Long COVID. (Sources: WHO, CDC.)

Slide 5: 72% increased risk. The risk of developing an autoimmune disease rose by up to 172% after infection, per a study following people from 2020 to 2022. Up-to-date COVID-19 vaccination can reduce the likelihood of developing an autoimmune condition after infection. (Sources: Nature Reviews Rheumatology, Cedars-Sinai, Journal of Translational Medicine, Clinical Rheumatology, eClinical Medicine.)

Slide 6: Other Illnesses. SARS-CoV-2 can also activate other viruses that have been lying dormant, like Epstein-Barr and herpes viruses. Studies have found kids with prior COVID-19 infections had a greater risk of RSV infections.

Always feel run-down? Practice harm reduction and learn how you can protect yourself from more damage.

(Sources: Family Medicine and Community Heath (BMJ), Frontiers in Immunology, Nature, Cell.)

Slide 7: 49% of COVID infections are asymptomatic, which means you may not know if you are actually sick. This is why it's important to take a multilayered approach (one or more of the following) to protect yourselves and others:

N95 and KN95 masks

HEPA air filtration

Good ventilation (carbon dioxide <800 parts per million)

Up-to-date vaccinations

Rapid tests before gathering

Attention to wastewater levels of COVID-19

(Sources: The Lancet Regional Health, CDC)

Slide 8: What we don't know.

The long term impact on other illnesses. Outside of the influence on RSV and reactivated viruses, it's to be determined whether altered immune systems predispose people to conditions like other infectious diseases, neurodegenerative diseases, or cancer.

Why some people's conditions persist. We don't yet know why some people recover and their immune system restores, and why others continue to decline.

What diagnostics and therapies can help restore the immune system. More identifiers like viral load tests and biomarker tests, plus treatments for Long COVID, are needed to help the millions living with the condition.

(Sources: Dr. Akiko Iwasaki, Science)

End image descriptions.]

Adding back in OP's links for ease of access after reading the image descriptions:

Yale School of Public Health's original Facebook Post

Sources per slide, listed on Google Docs

Slide 6 correction: “Correction: We’ve updated slide 6 to read 72%, not 172%, though other studies have found the risk of autoimmune disorders increased by 198% following infection.”

Yale School of Public Health

Sources per slide

Slide 6 correction: "Correction: We've updated slide 6 to read 72%, not 172%, though other studies have found the risk of autoimmune disorders increased by 198% following infection."

[rudyabaut]

False: Fauci, Gates, Epstein and Soros have ties to drug company Moderna

EXCLUSIVELY for Covid-19 Conspiracy Theories Suckers 

View video before it is taken down...

MODERNA FAUCI(https://www.youtube.com/watch?v=qAZFl1bhMH4)

Then come back to reality...

Read this: Fact check: Fauci, Gates, Epstein and Soros have no ties to drug company Moderna

by Chelsey Cox, USA TODAYSept. 11, 2020

The claim: George Soros founded Moderna, Jeffrey Epstein was an investor, Anthony Fauci was its first CEO and Bill Gates was his college roommateNews of biotech company Moderna's planned development of a vaccine against the coronavirus, the virus that causes COVID-19, has incited internet conspiracy theorists. A popular social media claim links certain high-profile individuals to Moderna and their apparent investment in the vaccine. USA TODAY reported on Moderna's progress in late August.

One such post by blogger Lynna Smith went viral. Smith posted the claim to Facebook on Aug. 12 with a link to a video uploaded to a corresponding YouTube account.

The video outlines alleged connections between Hungarian-American billionaire George Soros, accused sex offender Jeffrey Epstein, infectious disease expert Dr. Anthony Fauci and Microsoft co-founder Bill Gates as part of a larger conspiracy theory about government-mandated vaccinations against the coronavirus.

The narrator of the video claims Moderna already has the vaccine. It also states Fauci, a graduate of Cornell University, was Moderna's first CEO. Fauci's ties to Gates began at Cornell, the video alleges, because the two were roommates.

The video also states IG Farben, a company that was "heavily involved" in experiments during World War II, was run by Soros, a "Jewish Nazi" who later became an American citizen. Soros apparently formed Moderna from IG Farben.

Finally, the video claims Epstein, the billionaire financier who died in prison while awaiting a trial for sex-trafficking charges, was a major financial backer of Moderna.

Smith summarizes the "relationship" between Soros, Fauci, Gates and Epstein in the post caption, finishing with, "DO YOU GET IT NOW."

Smith is described as a "Truthseeker" and proudly declares "2 of my pages were deleted by FB" on a Facebook profile page. Smith also claims to manipulate mainstream media and references U.N. Agenda 21 in a Gab.com profile. Gab.com is a social network that "champions free speech, individual liberty and the free flow of information online," according to its website.

USA TODAY reached out to Smith for comment.

Another version of the claim was posted to the Facebook page for The Meme Aesthetic, an account that curates "the worst memes on the internet," according to its Instagram page. 

Was Soros a 'Jewish Nazi?'

Soros was born in Budapest in 1930. His father, a Jewish lawyer, forged papers that disguised their religion during the Nazi occupation of Hungary, according to the BBC. 

There is no evidence of Soros joining the Nazi party during WWII — he would have been 14 years old when the Nazis surrendered in 1945 — or anytime during his transformation from London investment banker to billionaire American philanthropist. 

Soros has openly supported the Democratic Party. The BBC reported Soros has been the target of right-wing attacks founded in Nazi-era conspiracy theories about Jewish bankers plotting a "New World Order."

Who founded Moderna?

The founding of the biotech company is incorrectly attributed to Soros in the claim. Harvard University professor Dr. Derrick Rossi founded Moderna in 2010 to manufacture his research-based therapeutics, according to a 2014 interview with the Journal of Young Investigators.

"The biotech company is called Moderna Therapeutics and it’s probably one the most successful young biotech companies in Boston/Cambridge right now. It is only 4 years old. ... The technology at the heart of the company, which we developed in my lab, is very exciting and very powerful," Rossi told JYI.

Soros did not create the company from IG Farben. The German chemical and pharmaceutical conglomerate was dissolved by Allied forces after WWII for manufacturing gas chamber poison and exploiting slave labor, according to The New York Times. Its most important factories formed the basis of chemical companies Bayer, Hoechst AG and BASF, but not Moderna. 

Was Fauci the CEO for Moderna?

Moderna's founding team was comprised of Doug Cole and Noubar Afeyan, according to the website for investor Flagship Pioneering. Afeyan is also Flagship's founder and CEO.

Stéphane Bancel is credited by Flagship Pioneering as the founding chief executive officer of Moderna Therapeutics. He has served in this role since 2011, according to Moderna's website.

A search for "Fauci" on Flagship Pioneering's website produced no results. Fauci is included in two search results on Moderna's website. The first mentioned his interview with National Geographic about an experiment conducted by Moderna. He is listed as the director of the National Institute of Allergy and Infectious Diseases in that entry. NIAID is part of the National Institutes of Health.

The other search result is a 2019 Shareholder Letter that names Fauci as a co-reviewer of a vaccine platform Moderna is working to improve.

Fauci is not identified as the former CEO of Moderna in either instance. Widely available evidence, like his official biography on the NIAID website, states Fauci has served as director of the institute since his appointment in 1984.

Were Fauci and Gates college roommates?

Fauci received his medical degree from Cornell University Medical Center in 1966, according to the Brooklyn Reporter. That is nearly a decade before Gates entered Harvard University. NPR reported Gates intended to study pre-law but shifted his focus to math and science before taking his first of two leaves of absence in 1975. He was eventually awarded an honorary degree in 2007. Gates and Fauci did not attend the same colleges and could not have been college roommates.

The Bill and Melinda Gates Foundation is listed as one of Moderna's collaborators, according to Flagship Pioneering. 

What is Epstein's relationship to Moderna?

Epstein left his position as a tax adviser with Bear Stearns Cos. to start his own investment company in 1982, according to USA TODAY. Details about Epstein's Financial Trust Co. are reportedly vague, but the company is not listed as a primary stockholder in Moderna, according to CNN Business.

A search for "Jeffrey Epstein" on the websites for Moderna and Flagship Pioneering generated no results.

Our rating: False

We rate this claim FALSE, because it is not supported by our research. George Soros did not found Moderna, as the claim states. Dr. Anthony Fauci has served as director of the National Institute of Allergy and Infectious Diseases since 1984, but never worked for Moderna. Bill Gates and Fauci attended different colleges and could not have been roommates. Lastly, Jeffrey Epstein's company Financial Trust Co. is not a major stakeholder in Moderna, according to records.

Our fact-check sources:

> National Institute of Allergy and Infectious Diseases, retrieved Sept. 4, 2020: "Anthony S. Fauci, M.D."

> Flagship Pioneering, retrieved Sept. 4, 2020: "Companies: Moderna"> Flagship Pioneering, retrieved Sept. 4, 2020: "People: Noubar Afeyan, Founder & CEO

"> Flagship Pioneering, retrieved Sept. 4, 2020: "People: Stéphane Bancel, Venture Partner"

> BBC News, May 31, 2018, (archived): "Profile: Billionaire philanthropist George Soros"

> CNN Business, retrieved Sept. 4, 2020: "Moderna Inc. Shareholders"

> USA TODAY, July 8, 2019: "Who is Jeffrey Epstein, the billionaire charged with sex trafficking girls as young as 14?"

> NPR Legacy, retrieved Sept. 4, 2020: "Timeline: Bill Gates, From Geek to Gazillionaire to Do-Gooder"

> Brooklyn Reporter, March 2, 2020: "Brooklyn-born disease expert Dr. Anthony Fauci says we may be on the brink of a pandemic"

> Journal of Young Investigators, Oct. 1, 2014: "Interview with Dr. Derrick Rossi of Moderna Therapeutics"

> Moderna, retrieved Sept. 4, 2020: "Moderna’s Work on a COVID-19 Vaccine Candidate"

> Moderna, retrieved Sept. 4, 2020: "Moderna 2019 Shareholder Letter"

> Harvard Stem Cell Institute, retrieved Sept. 4, 2020: "Derrick J. Rossi, Ph.D."

> The New York Times, May 2, 1999: "THE BUSINESS WORLD; I.G. Farben: A Lingering Relic of the Nazi Years"

Learn more at https://www.usatoday.com/story/news/factcheck/2020/09/11/fact-check-fauci-gates-soros-epstein-not-tied-moderna/5715707002/

Related reading:

Fact check: U.N. Agenda 21/2030 'New World Order' is not a real document (https://www.usatoday.com/story/news/factcheck/2020/07/23/fact-check-uns-agenda-21-2030-agenda-wont-create-new-world-order/5474884002/)

Is George Soros paying protesters? Soros' conspiracy theories surge as protests sweep nation(https://www.usatoday.com/story/money/2020/06/21/george-soros-conspiracy-theories-protests/3232738001/)

[petglue9-blog]

Skin Tag Removal center, Plymouth, Devon.

Skin Tag Removal clinic, Plymouth, Devon.

Content

Facelift (rhytidectomy).

Fat Freeze!

every Little Thing You need To understand About Cryolipolysis (fat Freezing) treatment Of tummy Fat

Cellulite

sight a Few Of Helena Fryer's patients prior To as Well As After Skin Tag treatment right Here:.

Technologies & Products made Use Of.

Police officer primarily stems from the 1500s English word 'cap', indicating to seize, from Middle French 'caper' for the exact same word, and possibly linked additionally to Scicilian and also Latin 'capere' implying to record. The full form Copper is partially derived as well as use reinforced via the metallic copper badges put on by very early New York cops sergeants. By the way the patrolmen had brass badges and the captains silver ones. cloud nine/on over the moon - severe happiness or euphoria/being in a state of severe joy, not necessarily however possibly due drugs or alcohol - cloud seven is an additional variation, yet blissfulness tends to be the most popular.

Words and also language may transform gradually, yet the noise of a fart is just one of life's more sustaining attributes. consume crow - recognize a mistake, suffer embarrassment - the expression's origins are American, from imagery and also mythology from the late 19th century. Crow would certainly have been considered an instead distasteful dish, similar to the original English Umble Pie metaphor from the 1700s. According to etymologist James Rogers, eating crow ended up being the topic of a tale reported in the Atlanta Constitution in 1888, which informed the tale of an American soldier in the Battle of 1812, that fired a crow during a ceasefire. A British policeman matched the bear up his shooting as well as asked to see the weapon, which when handed to him, he switched on the soldier, reprimanding him for trespassing, and also compeling the soldier to consume a piece of the dead crow. However, on having the gun returned to him, the soldier quickly transformed the weapon on the policeman, as well as made him consume the rest of the crow.

Facelift (rhytidectomy).

As a whole, the therapy works finest on people older than 30 with mild-to-moderate skin laxity. fat freezing will certainly be called for to find who is finest matched for this kind of treatment. Until now, HIFU has actually been located to be a promising treatment that could transform facelifts, especially in younger individuals that do not desire the hazards as well as healing time related to surgery. My skin was still red like red beard and irritation, I could not also have warm a shower which made it, a lot more, worst and also worst. I give thanks to God as well as Dr Berry for that, made my life return to regular.

In the laparoscopic sacrohysteropexy with mesh, The cervix is comprehended by unique forceps. A laceration is after that made in the vaginal skin surrounding the cervix and a soft nylon mesh is after that sutured to the cervix and also the genital skin closed over it.

Hoag paid off the authorities to get away prosecution, however eventually paid the rate for being also creative when he tried to reduce the police out of the offer, resulting in the pair's arrest. In explaining Hoag at the time, the police were allegedly the initial to use the 'wise aleck' expression.

If you have very early recollections of use or ideas of exact origins or authors of any one of the above expressions please let me understand, and I'll release the searchings for on this page in the main listing. Let me recognize additionally if you desire any mysterious expressions contributing to the list for which no published origins seem to exist. Can you help discover the earliest beginnings or precise resources of some fairly current expressions and numbers of speech? Below are a couple of interesting sayings for which for which completely pleasing beginnings appear not to exist, or existing explanations welcome growth and even more information. The primary advantages of using these lotions like rapid virgin spray is that they are made from entirely natural herbs hence lack any type of kind of type of adverse results. Older people with even more thorough photo-ageing, serious skin laxity, or exceptionally droopy skin on the neck aren't terrific prospects along with might need surgical procedure.

The basis of the definition is that Adam, being the first guy ever, and also therefore the farthest eliminated from anybody, symbolizes a male that any person is least likely to know. Out of passion, an 'off ox' would have been the monster drawing the cart on the side farthest from the motorist, and for that reason much less recognized than the 'near ox'. This expansion to the expression was American; the 'off ox' as well as various other expansions such as Adam's brother or Adam's foot, are just created to exaggerate the distance of the acquaintance.

. Please note, however, that each person might react in a different way to the therapy.

This innovative procedure tones, tightens as well as companies the skin on the face.

Our Cancer Details Nurse Specialists are devoted cancer cells nurses available to talk to on our Macmillan Cancer Cells Support Line.

• Crepey and old and wrinkly skin throughout the face and also inner arm, décolleté, abdomen, internal thighs and also knees, etc

No downtime-- you may use makeup immediately following therapy.

Online Area An anonymous network of people affected by cancer which is free to sign up with.

To achieve this, our HIFU innovations target the 4 various layers of skin that affect physical appearance; specifically, the epidermis, dermis, subcutaneous fat, and superficial muscle aponeurotic system.

Fat Freeze!

The above usage of the 'black Irish' expression is perhaps supported since it was also a term given to a former servant who took on the name of an Irish proprietor. Whether this was in Ireland, the West Indies, or in other places is not clear, and in any event is not likely to have been the primary derivation of the expression provided various other more common aspects. containers - eyeglasses, or the eyes - an easy reducing of words field glasses, initially appeared in English c. 1930, potentially from the armed forces or London, for which this sort of short-form slang would certainly have been normal. almanac - diary - either or both from the Arabic 'al manac' indicating 'the journal' and/or from Saxon term 'al-mon-aght' suggesting 'all moon follow', which was the record of new as well as full moons. Cohen suggests the beginning dates back to 1840s New york city City defrauder Aleck Hoag, who, with his wife posing as a prostitute, would certainly burglarize the consumers.

every Little Thing You need To find Out About Cryolipolysis (fat Freezing) treatment Of stubborn Belly Fat

Dosh appears to have originated in this form in the US in the 19th century, and afterwards reappeared in a lot more preferred use in the UK in the mid-20th century. doss-house - harsh resting accommodation - the term is from Elizabethan England when 'doss' was a straw bed, from 'dossel' meaning package of straw, in turn from the French 'file' meaning package. Before c. 13th century the word was dyker, from Latin 'decuria' which was a trading system of ten, initially utilized for pet hides. dead pan - expressionless - from the 1844 rhyme (' The Dead Pan') by Elizabeth Browning which told that at the time of the crucifixion the cry 'Terrific Frying pan is dead' swept across the ocean, and 'the responses of the oracles ceased for ever before'. dandelion - wild flower/garden weed - from the French 'dent de lyon', indicating 'lion's tooth', due to the jagged shape of the dandelion's fallen leaves. According to Chambers the plant's name came into English in the late 1300s originally as French 'dent-de-lyon', progressing with dandelyon, additionally generating the surname Daundelyon, before reaching its present English kind.

Can alum tighten the Virgina?

Although chemicals and vaginas are not a good mix, applying potassium alum to the vaginal walls has been touted as an effective home remedy. It's said that the astringent properties of the chemical are good at tightening the vaginal tissue.

London meteorologist Luke Howard established the first extensively approved cloud name and classification system, which was published in 1803. The system is essentially still in use today, albeit raised from Howard's original seven-cloud framework.

Names of blossoms are amongst numerous other usual English words which came into English from French in the late middle-ages, the reason for which is discussed in the 'pardon my French' beginning. In much of the expression's common usage the meanings seem to converge, in which the hybrid 'really feel' is just one of domination/control/intimacy in return for payment/material reward/safety/protection. Using the expression as a straight insult, where the significance is to examine an individual's parentage, is found, but this would not have actually been the beginning, and also is a much more current retrospectively used definition. dachshund - short-legged dog - the dog was initially a German breed made use of for hunting badgers. Words appears to have pertained to England in the last 19th century. cop/copper - police officer - Some recommend this is a phrase from 'Constable On Patrol' however this is a retrospectively applied description.

What are the best lasers for skin tightening?

Now let's have a look at 3 of the best and most effective laser treatments for skin tightening: Fraxel, Titan, and Nlite.Fraxel. The Fraxel laser treatment is mostly used to diminish or eradicate aging skin. Titan. Thinking about a Titan facelift procedure? Nlite.

We will rapidly develop the facts of your case and describe our method for acquiring payment for a botched genital rejuvenation in straight-forward terms. From obtaining medical reports to arbitration and/or court process, we will make sure that you feel completely notified as well as supported every action of the method. As mentioned formerly, lots of doctors may not finish a vaginal vault suspension at the time of prolapse surgical treatment, also if the client has safe prolapse, because of the hard and intricate nature of the treatments reviewed above. This can bring about issues such as a reduced vaginal canal, pelvic discomfort, uncomfortable sexual intercourse, urinary symptoms that can happen post-operatively if the genital vault had not been appropriately suspended. This risk exists whether the treatment is completed via an open cut or the laparoscope.

Cellulite

The allusions to floating on air and also 'being high' obviously fit the cloud allegory as well as would have made the expression naturally very appealing, especially in the context of alcohol and drugs. See for fun as well as even more weather interests the weather condition test on this web site.

sight a Few Of Helena Fryer's clients before and After Skin Tag treatment right Here:.

Does insurance pay for labiaplasty?

Insurance guidelines Unfortunately, in most cases insurance will not cover or approve labiaplasty surgery. Insurance companies look at a procedure and determine if it is “medically necessary”. They do this in a couple of different ways. One way is to define surgery as reconstructive or cosmetic.

Cryopen ®. say Goodbye To growths, Skin marks therefore a Lot More!

The 'bottoms up' expression then normally referred to looking for the King's shilling at the bottom of the flask. If you recognize anything more regarding the origins of "throw me a bone" - particularly the expression taking place in a language aside from English, please inform me. The flag is a blue rectangle with a solid white rectangular shape in the center; 'peter' is from the French, 'partir' suggesting 'to leave'. In addition,, heaven and white 'blue peter' flag is a basic nautical signal flag which stands for the letter 'P'. The letter 'P' is connected with the word 'peter' in lots of phonetic alphabets, consisting of those of the English as well as American military, as well as it is feasible that this phonetic language organization was affected by the French 'partir' origin.

Is Thermiva safe?

Thermiva is an FDA approved treatment cleared for dermatological and general surgical procedures. It's a safe and effective procedure that can help restore your confidence and pleasure! You should also know sometimes there may be side effects associated with Thermiva.

ciao - Italian greeting or farewell, and also typical English colloquialism meaning 'goodbye' - noticable 'chow', is derived from Italian words 'schiavo vosotro' indicating 'I am your slave'. Chambers and also OED are clear in showing the earlier Latin complete type of 'carnem levare', from medieval Latin 'carnelevarium', and that the derivation of the 'val' element is 'doing away with' or 'getting rid of', as well as not 'saying goodbye, as some recommend. OED as a matter of fact states that the connection with Latin 'vale', as if claiming 'goodbye to flesh' results from 'preferred' etymology. by and large - generally/vaguely/one way or one more - one of a number of maritime terms; 'typically' literally implied 'to the wind as well as off it'.

An additional analysis, and also certainly a belief when held by some, is that sneezing expelled ghouls from an individual's body. A contributory element was the organization of sneezing with the Black Death which ravaged England as well as specifically London in the 14th as well as 17th centuries. In more current times the expression has been connected to the misconception that sneezing creates the heart to stop beating, further strengthening the Bless You personalized as a protective superstitious notion. blarney - persuasive yet vacant words - from the spoken laziness tactics of Cormack MacCarthy, 1602, in holding the castle of Blarney in Ireland, near Cork, despite consenting to commend the English as component of the surrender terms.

Is V Tight Gel permanent?

A V Tight Gel, when used in the right manner, will certainly have long-lasting effects. However, its outcome is not permanent. The user must keep using it on a regular basis to enjoy its positive results.

Keep in mind that a wind is described according to where it comes from not where it's mosting likely to. Sailing 'by' a South wind would suggest cruising essentially in a South instructions - 'to the wind'. box and die/whole/hole box and pass away - see see 'entire box and die' feasible meanings and beginnings listed below. Bars and also drinkers familiarized this method as well as the customized of alcohol consumption from glass-bottom flagons began.

In a much larger research study of 93 people, 66 per-cent of those taken care of in addition to HIFU watched an improvement in the appearance of their skin as well as back after 90 times. In the most general terms, genital plastic surgery, is performed by getting rid of excess cellular lining. The specialist also tightens the muscle mass as well as surrounding soft cells in the genital location. fat freezing is a surgical procedure to lower the size of the labia minora-- the flaps of skin either side of the vaginal opening. Several females experience serious pain and also discomfort due to large labia, which can prevent them from joining typical, everyday activities such as certain sports as well as can make intercourse uncomfortable and humiliating. Our legal group are committed to ensuring clients feel completely supported throughout the cases process.

[accraposts-blog]

16 Most Incredible Health Benefits Of Bitter Kola

Garcinia Kola popularly called Bitter Kola is a bitter traditional fruit common in the West Africa and it is generally considered medicinal with no specified side effects.

Garcinia Kola belongs to the species of a tropical flowering plant that produces brown nut like seeds. Traditionally, the fruit, seeds, nuts and the bark of the bitter kola plant have been used for centuries for herbal medicine to treat several ailments.

This bitter fruit, which is believed to contain a high source of vitamins and minerals such as Vitamins A, C, E, B1, B2, B3, fiber, calcium, potassium, and iron, also carry other antioxidants and the usage is not limited to traditional activities alone.

Bitter Kola

Bitter Kola was eaten mostly by the elderly people because of their belief that it could prolong life. Imperatively, researchers in modern science have revealed that bitter kola contains chemical compounds that will help the breakdown of glycogen in the liver and has other medicinal uses which account for its longevity properties in man.

Bitter kola is known as ‘Orogbo’ in Yoruba land, ‘Miji-goro’ in Hausa land and in Igbo land as Akiilu.

Bitter Kola leaf and fruits

History has it that Garcinia kola is a specie of flowering plant in the Clusiaceae or Guttiferae family. It is found in Benin, Cameroon, Republic of Congo, Ivory Coast, Ghana, Gabon, Senegal, Liberia, Sierra Leone and Nigeria. This natural habitat is subtropical or tropical moist lowland forests.

It has been used for centuries in folk medicine to treat ailments from coughs to fever. According to a report from the Center For International Forestry Research, Garcinia kola trade is still important to the indigenous communities and villages in Nigeria.

Bitter Kola Tree

Owing to this, research was carried out by accredited institutions to find out the possible healing attributes of the bitter kola plant.

Health benefits of bitter kola

It is possible to use bitter kola to improve several medical conditions for a short period. This might work for depressions, fatigue problems, atonic diarrhea, migraine, and other disease conditions.

Healthy benefit of bitter kola

Bitter Kola tree have been widely used both in medicine and in cosmetology due to their stimulating, astringent, draining, decongestant, antioxidant, anti-inflammatory, vaso-protective, lipolytic and a number of other properties. Health benefits of bitter kola make it a fair alternative for a list of pills and medicines.

1. Bitter kola serve as remedy for osteoarthritis

Osteoarthritis is the degeneration of joint cartilage and the underlying bone that causes pain and stiffness, especially in the hip, knee, and thumb joints. It is a common form of arthritis.

And according to the National Institute of Health, the causes of Osteoarthritis can include joint injury, obesity, and aging. Research as also shown that bitter kola can reduced inflammation disease and pains. It also increased joint movement in patients that had osteoarthritis symptoms.

Apart from the aforementioned on Osteoarthritis, bitter kola can also repel snakes. It can be used to chase snakes away. For snake prevention you can spread it around the building.

Professor, Maurice Iwu, once said that bitter kola can be used to prevent Ebola Virus Disease (EVD).

2.  Bitter kola helps to combat sexually transmitted diseases (STDs)

Bitter kola has also be deduced to be a potent antibiotic that could be effective in the treatment of HIV and AIDS due to its antibacterial, detoxification, and cleansing properties

Since the emergence of sexually transmitted diseases, reputable scientists have been battling day and night to bring a permanent solution to the disease.

Although their battle may seem somewhat difficult as a result of the complexity of the diseases, yet results have shown that seed and leaf of bitter kola have antibacterial activity on clinical isolates of Staphylococcus aureus, Escherichia coli, Salmonella typhi and Streptococcus pyrogens.

3. Bitter kola helps to improves immune system

Bitter kola helps to boost immune system

Bitter kola provide the immune system with all the needed supports in order to protect one from attacks of harmful toxins and effective immune response against strange particles.

This high amount of antioxidants found in bitter kola does not only help fight bacteria and other illnesses, it also helps the body to increase its immunity levels.

And when the immunity level of the body is increased, it becomes strong enough to fight against any foreign contaminant.

4. Bitter kola helps cure impotence

With bitter kola impotent is an history because studies have shown that when it comes to the improvement of sexual performance, especially among men, bitter kola is king among all other suggested herbs.

Bitter Kola does not only increase sex drive, it also improves the sexual performance of men who consume it. Research indicate that for the seed to be effective, it is advisable for the seed to be chewed some minutes before the intercourse.

It has also been confirmed that bitter kola helps to increase sperm counts and promote male fertility, which can be useful for those of you out there looking into adding a little one to your family.

Not only that, but bitter kola can actually help to boost libido in men as well. It’s a potent aphrodisiac and studies have shown it can actually temporarily boost testosterone levels.

5. Bitter kola aids proper functioning of the lungs

Bitter kola aids proper functioning of the lungs

The fibers and lung tissues are not only strengthened when bitter kola is consumed regularly in a considerate amount, it also stabilises any other counter effect.

In addition, it helps in the maintenance of good respiratory tract as well as treating chest cold. It has a favourably high antioxidant content for a healthy body.

Bitter kola’s benefit to lung properties are attributed to its high antioxidant content. So, if you are a smoker or even a passive smoker, definitely bitter kola is the cure.

6. Bitter kola assists with weight loss

Bitter Kola Assist weight loss

Bitter Kola has been revealed to be a natural hunger suppressant and also increases the urge to drink more water. Regular use of bitter kola can help you reduce your weight faster than gym could.

People that are placed on a special diet and wish to lose some weight can add bitter kola nuts to their meals and experience fewer food cravings throughout the day; using nuts as a snack can also help reduce hunger between meals.

7. Bitter kola serve as anti-malaria agent

Bitter kola serves as anti malaria agent

Kolaviron is an anti-oxidant and anti-inflammatory phyto-chemical. Kolaviron is a major constituent of garcinia seed which helps in treating malaria. Studies have also shown that chemical constituents in bitter kola have anti-malarial properties.

This is why traditional healers have for many years prescribed bitter kola for the treatment of malaria infections.There are no definite side effects of having this naturally occurring blissful plant. But, anything in excess or wrong proportion may show its evil side.

Therefore, it is advisable to use the seed on some certain occasions, because consumption of bitter kola is found to have some side effects.

To some certain degree it has been proven that bitter kola stem, bark and seeds are used for the treatment of acute fever, inflammation, respiratory tract and throats infections.

8. Bitter kola fights Glaucoma (eye pressure)

Glaucoma, known as eye pressure is a condition of increased pressure within the eyeball, causing a gradual loss of sight. Glaucoma could result in permanent blindness if left untreated.

However, bitter kola has been found to be an amazing remedy for the eye. This is stated according to Lagos State University Teaching Hospital journal, “when bitter kola is eaten, at least twice a day, it could successfully reduce the eye pressure”.

9. Bitter kola helps r

educe constipation

Kola nut functions as a dietary fibre in food as it helps in the prevention and treatments of health conditions that relate to the digestive system which includes but is not limited to bloating, constipation and other conditions that disrupt the bowel movement.

10. Bitter kola enhances cancer treatment

Bitter kola have been found effective in stopping growing of tumours and cancerous disease in human body. Researches show that the presence of a chemical compound known as phytoestrogens in bitter kola is used for cancer treatment and reduce the growth of tumour cells.

Similarly, there is a non-steroidal plant compound contained in kola nut extracts which have the ability to terminate the growth and development of prostate cancer cells in the body.

11. Bitter kola increases mental alertness

The caffeine content in bitter kola makes it a good stimulant or psycho-stimulants for the central nervous system; as it helps to improve awareness, mood and elevated mood.

These nuts, specifically bitter kola are regarded as cognitive boosters.

12. Bitter kola helps p

romotes diuresis

Kola nuts and bitter kola contain bitter chemicals such as caffeine and theobromine which serve as natural diuretics. This implies that the bitter content in these nuts helps to increase water and salt expelled from human body; and some minor sicknesses in the body are flushed out through urine in the process which makes them beneficial to human health.

13. Bitter kola boosts fertility

Nigerian women who experience infertility problems sometimes eat bitter kola to improve fertility.

14. Bitter kola helps staying awake

One of the things bitter kola is commonly abused of is its intake to prevent sleep which is possible because of its rich caffeine content, and when it’s taken regularly and in excess can at a point cause insomnia including other related problems such as stomach irritation, nervousness, restlessness, and more.

15. Bitter kola serves as natural therapy for cold

This is one of the ancient uses of bitter kola which extend till the recent times. These nuts have been found to be medicinal since the olden days as natural remedy for chest cold. Bitter kola help to enlarge the alveolar sac and duct thereby providing relief for chest cold and prevent the symptoms of cold.

The presence of caffeine in bitter kola also contribute to this effect but always consult the doctor before using this therapy because excess caffeine can cause adverse reactions.

Must Read: Health Benefit Of Soya Bean

16. Bitter kola can help balance blood sugar levels

Bitter kola isn’t just useful for treating malaria. It can also be effective for individuals who have type 2 diabetes as a means of keeping their blood glucose levels stable.

Studies have found that the seeds from the plant are capable of reducing elevated blood glucose levels. This makes it ideal for both treatment of type 2 diabetes as well as for any complications that can arise from the condition.

In addition to that, studies performed on rats that had type 1 diabetes found that bitter kola could actually prevent the cognitive and motor dysfunction that is typically associated with the disease.

Side effects of bitter kola

Consumption of bitter kola nuts is completely safe. I personally haven’t experienced any sort of side effects or anything like that with eating bitter kola.  As with any form of natural supplement or remedy however, you should definitely consult with your family doctor before use.

With that being said, there have been reports of certain side effects that can occur due to bitter kola usage. As bitter kola do contain caffeine and can affect the central nervous system, most of the negative effects are felt by individuals who are sensitive to caffeine in general.

The most common side effects associated with bitter kola include:

Dry mouth

Insomnia

Rapid heartbeat

Nausea

Stomach cramps

Diarrhea

Hives

If you experience symptoms such as hives or any other sign of an allergic reaction, you should immediately stop taking bitter kola and consult with your doctor.

[jobsearchtips02]

Meet billionaire Expense Ackman, who made billions off coronavirus crash

REUTERS/Richard Brian.

Billionaire hedge-fund supervisor Bill Ackman made $2.6 billion off a questionable bet that the coronavirus would crash the stock market last month.

Ackman was accused of making inflammatory remarks throughout an appearance on CNBC with the intent of moving the markets to increase his earnings however denied it in a press release

Ackman, worth $ 1.6 billion, has a history of making controversial bets.

While most of the world saw their nest eggs decimated as the stock exchange entered into a free-fall over coronavirus worries last month, one hedge-fund supervisor was raking in billions.

Costs Ackman, the chief executive of Pershing Square Capital, made $2.6 billion off a $27 million bet that the pandemic would tank the marketplace. Ackman has a history of controversial bets that earned him a $ 1.6 billion fortune and an examination by the New York District Attorney’s Office.

A representative of Ackman at Pershing Square Capital did not right away respond to Service Expert’s request for comment on Ackman’s profession, net worth, residential or commercial property holdings, or domesticity.

Keep checking out to find out more about Costs Ackman.

William Ackman, 53, was born and raised in a wealthy suburban area outside of New york city City.

Bill Ackman.

Reuters/ Allen Fredrickson.

Ackman was raised in Chappaqua, the wealthy New york city suburb of north of New york city City, according to The Daily Mail Chappaqua is likewise home to Costs and Hillary Clinton, Ben Stiller, and Vanessa Williams, according to The Daily Mail

Ackman’s father, Lawrence Ackman, owned an industrial real-estate financing company, according to The Minneapolis Star Tribune His mom, Ronnie Posner Ackman, serves on the board of New York’s Lincoln Center, according to The New York Times

Ackman made a bachelor’s degree and MBA from Harvard, according to Forbes Quickly after graduating in 1992, Ackman established an effective investment company with a former schoolmate called Gotham Partners at age 26, The Minneapolis Star Tribune reported. The company achieved success however Ackman chose to wind it down in 2002, mentioning a series of lawsuits.

In 2003, Ackman was investigated by the New york city State Attorney General Of The United States over Gotham’s trading practices.

Costs Ackman.

No charges were ever submitted, Ackman said the extremely publicized investigation was difficult on his household.

” Individuals look at you amusing,” Ackman told The Minneapolis Star Tribune of the occurrence in2008

Ackman went on to found Pershing Square Capital Management with $54 million in 2004.

The cash was a mix of funds from his individual fortune and a loan from Leucadia National, according to The Minneapolis Star Tribune The firm was a near-instant success. In one of its finest years, 2014, Perishing Square posted 40%returns compared to the S&P 500’s 13%gain the exact same year, according to Investopedia

Pershing Square has large stakes in Chipotle Mexican Grill, Starbucks, and Hamburger King owner Restaurant Brands International Inc., Bloomberg reported. The value of its overall possessions tops $6.5 billion, according to Forbes

In a 2014 interview with Bloomberg, Ackman stated his guidelines for investing are to be bold, do the opposite of what everyone else is doing, and do lots of research study.

A Wendy’s junk food dining establishment is seen in Los Angeles, California U.S. November 7,2017

Ackman’s hedge fund made the majority of its money by purchasing stakes in big corporations, lobbying management to make changes to increase its stock rate, and after that quickly unloading their shares at an earnings, The Minneapolis Star Tribune reported in2008 Pershing Square purchased a large stake in fast-food burger chain The Wendy’s Company in 2004, pushed it to offer off its effective Canadian subsidiary Tim Hortons, and went on to cash out its financial investment at a profit, according to Investopedia

” His video game is to increase the stock and go out– quick,” Howard Davidowitz, then-chairman of a New york city investment banking and consulting company, told The Minneapolis Star Tribune of Ackman in 2008.

However Ackman is extensively thought about to be an activist financier, according to Markets Insider.

” What we provide for a living, purchasing stakes in business and working to make them better, more effective, more efficient, I think it’s excellent for the shareholders, I believe it’s terrific for the workers,” Ackman told Bloomberg “I think I can do some great with that, and it’s likewise extremely rewarding. I like my day job.”

Pershing Square’s success made Ackman a billionaire. He first appeared on Forbes’ billionaire’s list in 2013.

Source: Markets Expert

Ackman’s strong bets have made Pershing Square a lot of cash– but they have likewise cost the hedge fund billions too.

Bill Ackman.

Ackman’s 2012 short versus multilevel marketing supplement maker Herbalife was one of the most prominent mistakes of his career, according to Investopedia Ackman wager $1 billion that the company would fail, while fellow billionaire investor Carl Icahn made a long-lasting financial investment in the business, Organisation Insider formerly reported. Ackman publicly implicated Herbalife of being a pyramid plan whose stock cost was bound to hit absolutely no, according to The Wall Street Journal

Icahn and Ackman entered into a public battle over the business’s prospects that was called “the hedge fund equivalent of Stalingrad” by The Journal, with Icahn eventually emerging victorious. Ackman lost hundreds of countless dollars on Herbalife, Business Insider reported.

Ackman likewise made a questionable investment in near-bankrupt drugmaker Valeant Pharmaceuticals that led to a contentious Senate hearing over Valeant’s practice of purchasing existing drugs and offering them at inflated prices in 2016, Service Expert reported at the time. Valeant has since been renamed Bausch Health

Pershing Square also lost money on bets on now-defunct bookseller Border’s Group and big-box merchant Target Corporation, according to Investopedia The losses put the hedge fund into what Bloomberg called a “three-year losing streak” in 2019, prior to Ackman’s bet against the stock exchange.

Ackman’s hedge fund made billions of dollars when coronavirus fears sunk the stock exchange in March.

Costs Ackman (left).

Pershing Square invested $27 million in credit security on investment-grade and high-yield bond indexes earlier in 2020, when the market was widely perceived to be healthy, according to Markets Expert

Ackman has considering that used the revenues to strengthen Pershing Square’s financial investments in Berkshire Hathaway, Hilton, Lowe’s, Dining Establishment Brands International, Starbucks and Agilent, Markets Insider reported.

Ackman was implicated of actively sinking the marketplace to increase his profits.

Costs Ackman.

Ackman made an look on CNBC on March 18, declaring that “hell is coming” since of the outbreak, after tweeting comparable beliefs previously in the day. Ackman’s remarks sent the already unpredictable market down, triggering allegations from various news outlets and on social media that Ackman went on television with the intent of making his bet versus the marketplace more profitable, Forbes reported.

Markets plunged so dramatically that the market struck a so-called circuit breaker, stopping trading for 15 minutes, Markets Expert reported.

The billionaire defended himself in a declaration to Pershing Square financiers, writing that “By Wednesday, March 18 th at 12: 30 p.m., when I appeared on CNBC, we had actually currently sold a little over half of the notional amount of our CDS, realizing a gain of more than $1.3 billion, with the unrealized part of our hedge having a market value at that time of $1.3 billion for an overall of $2.6 billion,” Ackman wrote in a news release “Importantly, our hedge had currently settled prior to my going on CNBC.”

Ackman also ruffled plumes by safeguarding a fellow hedge-fund manager who has been connected to Bernie Madoff.

Ezra Merkin privately invested his customer’s cash with Bernie Madoff, losing billions after the Ponzi plan was exposed, according to Bloomberg Merkin was investigated by the New york city Attorney General Of The United States as a potential coconspirator of Madoff’s however settled his case in 2012.

” I’ve known him for 15 years,” Ackman stated. “I believe he’s a truthful individual, a smart person, an interesting individual, a smart financier. People don’t want to hear that since if you invested with Ascot you lost all your cash.”

Fellow hedge fund supervisor Michael Steinhardt of Steinhardt, Fine, Berkowitz & Co. likewise publicly defended Merkin, according to The Street

Ackman credited his new household for motivating his earnings.

Bill Ackman and Neri Oxman go to The New York Stem Cell Structure Gala And Science Fair at Jazz at Lincoln Center on October 7, 2019 in New York City City.

” Possibly it has something to do with being liked and getting married?” Ackman stated of his successes at an investor conference in April 2019, Bloomberg reported.

Ackman and his partner, retired Israeli Flying force lieutenant and MIT teacher Neri Oxman(who is best known for being a reported ex-girlfriend of Brad Pitt), invited a child in the spring of 2019, according to Bloomberg

The couple got together in 2017, after being introduced by both Ackman’s previous teacher and a college good friend following a contentious divorce from his very first spouse, landscape architect Karen Ann Herskovitz, according to Page 6

Ackman and Herskovitz have a “civil, however not warm, relationship,” an unnamed source informed Page 6 in2017 The former couple share three daughters, according to Page Six

Ackman promised to give a minimum of half of his fortune to charity.

Ackman has given more than $400 million in grants to organizations focusing on cancer research, education, economic advancement, and social justice, according to his structure’s site

Ackman and his wife also offered $26 million to Harvard in 2014, according to Philanthropy News Digest

He spent a big portion of the rest of his money on an extensive portfolio of luxury realty.

The Upper West Side of Manhattan.

Ackman bought a $225 million penthouse in the neighborhood, The Wall Street Journal reported in2018 Ackman also owns two other systems in another luxury pre-war building on Manhattan’s Upper West Side that cost nearly $221 million combined, The Journal reported.

They also own a six-acre estate in the Hamptons.

An aerial view of beachfront mansions in Bridgehampton, New York. Ackman’s house not visualized.

Ackman bought the properties, which are located in the town of Bridgehampton, for $235 million in August 2015, according to The Real Deal

The combined value of Ackman’s real-estate portfolio is more than $165 million, according to The Daily Mail

In his spare time, Ackman is a passionate tennis player.

Ackman has actually been playing considering that youth, according to Forbes

Ackman also has an interest in politics.

Costs Ackman.

We now have a business owner as president,” Vanity Fair reported Ackman said.

Ackman hasn’t always been a fan of Trump. In 2016, Ackman penned an essay in The Financial Times asking Bloomberg LP CEO and former New York City mayor Mike Bloomberg to run for president.

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[pknoepfl]

A TGIF weekend reading list of new stem cell pubs & headlines

A TGIF weekend reading list of new stem cell pubs & headlines

In case you have some free time for reading this week, here’s a list containing an assortment of interesting research articles and stem cell headlines. I’ve thrown some oddballs in there too including one article from May 1983, when I was just finishing up junior high. No, I didn’t write it. And no the headline for this current blog post is not referring to stem cell-themed pubs where you can go…

[fillyoursoulxx]

silas bishop - trauma headcanons

More often than not, Silas likes to keep things private. If you’re someone he’s ‘open’ with he has perfected the craft of presenting this really warm and personable guy. He still keeps a lot of himself, to himself due to trauma in his past though. Below is a list of trauma headcanons that have come up for Silas. The list’ll be updated as I think of them. 

physical trauma;

his father was abusive, physically, mentally and emotionally. He was and still is afraid of him to some extent, but as he got older and more capable of defending himself, the abuse lessened, aka he’d fight back. There were more than a few times he fantasized about watching him bleed out. the abuse only officially stopped when he took off at 17.

he has various cigarette burn scars on his left forearm and shoulder. They are feint now but he was self conscious about them once. 

he’s had his arm broken twice in two different places

his nose was broken once

There’s a scar on his left eyebrow where one of his brothers clocked him in the head with a bat ‘on accident’

if his father became particularly rough, he would make silas sit in an ice bath convinced it would take care of the bruising. most of the time he was allowed to get out before things got too serious, but he passed out once. he might’ve drowned/gotten hypothermia but his father wasn’t gonna ‘rot’ in some cell because he couldn’t keep his eyes open.

emotional & mental trauma;

His father enjoyed degrading Silas more than he did anything else. He endured a lot of name calling and disregard. 

His father often went out of his way to make Silas think he was in for a beating. He would surprise him coming in a door or wait until he was vulnerable somewhere.

In these instances, if Silas responded with fear, he usually received physical punishment, blow or some sort of chastising. 

trauma response; 

he doesn’t like anyone to sneak up on him. hates it. and when he’s out, he angles his back to corners/walls.

when he’s surprised, he rarely jumps/jerks but his jaw will flex/will grit his teeth or inhale sharply.

fight/flight/faun - Silas is all fight. It doesn’t matter if he’s out matched, he’d rather bleed out than run. That is unless it involves someone he actually likes, then he’s a runner, sometimes a pusher

he suffers from nightmares and is a very light sleeper. it’s rarer now, but still more often than he’d like.

has had more dark/suicidal thoughts than he’d care to admit. But he’s never attempted/gone through with anything out of sheer spite, knowing then his dad would be right about him

fidgets when anxious and has experienced panic attacks.

he enjoys affection and personal space isn’t a problem with it comes to women or close friends. he’s put on edge if other guys, especially larger guys encroach on his space.

for the more intimate moments, having his back touched/scratched is fine but likes to keep partners in front and tends to favor affection on his right side.

coping mechanisms;

he writes. it helps him get the ‘unhelpful’ thoughts out and make more sense of things. he keeps a journal/sketch book.

he runs a lot as well. whenever he has nightmares, cant sleep or is just having a rough time in general, he just takes off.

reading is an escape for him as well as star gazing. 

avoidance in general. he will spend days on the road or alone. if cornered with his emotions, he’ll fight it/get angry and if that doesn’t ‘fix’ the situation, he’ll run.

keeping busy. he likes to use as much of his time as possible & keeps his hands busy with work, hobbies or women. idle hands are the devil’s workshop.

Speaking of keeping his hands busy, he’ll often rub his neck or the scars on his wrist when he’s nervous/anxious. He’ll also tap his fingers against his thumb and other types of stems.

He squirrels away money like no ones business. He doesn’t socialize much and he doesn’t sleep a ton either, so he can work himself until he’s literally burnt out. But he always has to have some sort of money somewhere out of fear that if he ever truly runs out, he’d have to go back to alabama. 

[darleenrhunt]

Is Pet Insurance Worth It?

​It's an unfortunate reality of being a pet owner: you will most likely outlive your pet.  As a responsible pet owner, you will be faced with some very tough choices that may include medical treatments, or in some cases euthanasia. I know this is a difficult subject to discuss. With the rise of specialty insurances, such as pet insurance, it makes one wonder if these services are helpful or a scam. NBC columnist, Herb Weisbaum weights in on the pet insurance trend: Pet Insurance: A Good Deal? Or A Rip-Off? 

Is insurance the answer? When people ask me that question my answer is always the same: It depends. Buying pet insurance is both an economic and an emotional decision that needs to be based on your personal financial situation and what you’re willing to pay for peace of mind. “If you get the right policy, it can be an asset to the health care of that pet and have a significant impact on the bill that results from a visit in an emergency situation,” says veterinarian Jean Maixner, co-owner of Animal Critical Care & Emergency Services in Seattle. “Some people can’t afford the treatment so they ask us to euthanize their pet. It’s absolutely horrible,” Dr. Maixner says. “If people had acquired pet insurance before the emergency occurred, they might have been able to move forward with some reasonable treatment to help their pet.” ​

This is a bit disheartening and probably not the answer you were looking for.  Whether a pet policy is good, depends. Unfortunately, most people considering pet insurance find themselves in a difficult situation to begin with. When most pet owners begin their search for insurance types, they've already experienced some kind of medical issue or problem with their furry friend. For many, having to choose between the comfort of their pet and additional expenses can be a difficult choice to say the least. Pet Insurance Policies Compared Canine Journal did a lot of heavy lifting to provide the top 11 pet insurance providers. Here's a list outlining the rankings.

First: Healthy Paws 2009

Second: Pets Best 2005

Third: Petplan U.S. 2003

24PetWatch 2000

AKC Pet Healthcare 2003

ASPCA Pet Health Insurance 1997

Embrace 2003

Figo 2013 (will be added to our review this year)

Nationwide acquired VPI in 2014 and started selling pet insurance as Nationwide (VPI was founded in 1982)

PetFirst 2004

Trupanion 2000

You might be wondering what were the pet health providers ranked on. That's a great question. Here's what was listed on Canine Journal:

Policy Coverage

Visit Website

Customer Service & Reputation

Timeliness of Claim Payment

Price of Policy

Conclusion If you're interested in purchasing a pet insurance policy, you may want to read the reviews and understand the limitations of each policy. That could save you a lot of headache and heartbreak in the long-run. ​ Additional Resources:

Pet stem cell therapy

Is pet insurance worth it?

The cost of pet health insurance