#research types

[poorly-drawn-mdzs]

Stargazing, at the edge of the unknown.

[hellsitegenetics]

Hey are you willing to BLAST Kat Bolstad’s page on the AUT website? She’s the researcher who voiced over the colossal squid video and it’s making me so mad that people’s hatred of generative AI is so strong that they’re trying to crowd out an incredible cephalopod researcher who frankly speaks with a similar cadence to David Attenborough (those documentary skills!!!) especially during a time where we need to encourage women in STEM. This is the real damage generative AI is doing.

https://academics.aut.ac.nz/kathrin.bolstad

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Closest match: Arctia caja genome assembly, chromosome: 13 Common name: Garden Tiger Moth

(image source)

[illusioncanthurtme--art]

[reasonsforhope]

"A 25-year-old woman in China is the first person worldwide to have type 1 diabetes reversed through stem cell therapy.

The therapy used the patient’s own cells to create personalized stem cells, which were then used to grow fresh insulin-producing islets.

This breakthrough offers hope for millions with diabetes, potentially eliminating the need for daily insulin injections and reducing complications.

In a groundbreaking medical achievement, a 25-year-old woman in Tianjin, China, has had her type 1 diabetes reversed through a novel stem cell therapy. This marks the first time such a feat has been accomplished globally, offering new hope for millions living with the chronic condition.

The patient, who had been struggling with type 1 diabetes, underwent a pioneering treatment that involved converting her own cells into personalized stem cells. These stem cells were then used to grow fresh clusters of ‘islets,’ the hormone-producing cells in the pancreas responsible for regulating blood sugar levels.

As Nature reports, this therapy’s unique approach of transplanting the newly created islets into the patient’s upper abdomen near her pancreas sets it apart from previous islet transplant methods. This strategic placement allows for easier monitoring via MRI, a significant advantage over traditional liver transplants.

“I can eat sugar now,” the woman said on a call with Nature. After over a year since the transplant, she says, “I enjoy eating everything — especially hotpot.” The woman asked to remain anonymous for privacy reasons.

Experts are astonished at the results, according to Timesnownews. “They’ve completely reversed diabetes in the patient, who was requiring substantial amounts of insulin beforehand,” said Dr. James Shapiro, a transplant surgeon and researcher at the University of Alberta in Edmonton, Canada.

The implications of this breakthrough are far-reaching, as it could potentially revolutionize the way we treat diabetes. By using a patient’s own cells to create personalized stem cells, this therapy bypasses the limitations of donor islet shortages and the need for immunosuppressive drugs, which have hindered the success of conventional transplant methods.

‘If this is applicable to other patients, it’s going to be wonderful,’ diabetes researcher Daisuke Yabe of Japan’s Kyoto University told reporters via Daily Mail.

As the world watches closely, the success of this case sparks hope for the millions of individuals living with type 1 diabetes. It represents a significant step forward in regenerative medicine and paves the way for further research and development in the field."

-via Gadget Review, September 30, 2024

[rains-starlight]

This reminds me of you! SMAU

you send them photos that remind you of them <3

(ive wanted to make a SMAU so bad but could never figure out a prompt... I might in the future take suggestions cause it's soo fun!)

Part 2 | LI Version

✎﹏﹏﹏﹏﹏﹏﹏﹏﹏﹏﹏﹏﹏﹏

⭐ Xavier 🐰 & 🍐 Zayne 🩺

🐟 Rafayel 🎨

hes a chronic texter i couldn't make the conversation short 😭

🐦‍⬛ Sylus 🔫

🍎 Caleb 💥

✎﹏﹏﹏﹏﹏﹏﹏﹏﹏﹏﹏﹏﹏﹏ i wanted to be canon-compliant with the way they text so i also grabbed their stickers 🙇 thanks for reading! :D

[keferon]

🥒🥒🥒

Pickles for the post about differences between spacecraft and aircraft when it comes to their flying mechanics

Okay now I just have to make another presentation ahahshdhc. Since you was so kind to fund my research with pickles

[amphibianaday]

day 1421

[shiii-is-tired]

shopping list lore but it gets worse

these are just the ones i know and have found source abt so this is still open for additions

[sableeira]

You know how “the moon is beautiful tonight, isn’t it?” is used as an expression for love confessions? It’s said that Natsume Soseki came up with it after overhearing a student translate “I love you” to Japanese in a very literal sense. While there is no source confirming that this exchange actually happened, I still think a scene referencing the expression with Natsume randomly appearing would be hilarious

[hello-eeveev]

what’s so funny to me is that it seems like literally everything in Aeor terrifies Essek, but he has gone there several times with Caleb for research (aka wizard fun). They would have gone again if not for the Cerberus Assembly becoming too much of a presence there. Aeor is their established date spot.

He was basically doing the thing where you go to a scary movie or a haunted house with your crush so you have an excuse to hold hands lol

[qrowscant]

i wanted a machine guts sweater/shirt so here are some color tests

[ghurab-alzilal]

Damian: So you're going on a mission with Zatanna to the Middle East, right?

Raven: Yes, we leave tomorrow.

Damian: Well, there are some words you should memorize and use them with anyone you meet, okay? Repeat after me "ladaya sadiq."

Raven: La-dayaaa sa-diq?... Ladaya sadiq. What does it mean?

Damian: That's not the important thing, but don't forget to tell everyone there, you understand? All the lives around you could depend on it.

Raven: I understand, thanks for the advice, see you in a few days.

*The next day somewhere in the Middle East during a fight with some ifrites *

Raven, shouting out : LADAYA SADIQ!!!

An Imamah who went to help them : I'm happy for you but I don't think these demons really care if you have a boyfriend or not.

Raven: That's what it means?!

Imamah: *nods *

Raven, visibly upset : Well trust me, when I get my hands on him I'll stop having one.

[bloodypawwz]

If you’re comfortable with me asking, I keep seeing jirai mentioned on my dash but I don’t know what it means, it would mean so much if you could explain? You just seem really nice and like someone I could approach :>

haii np ill give u the best explanation i can !!

jirai is a subculture which originated in japan and translates to ' landmine ' ! it is typically used on people who are explosive and or have very instable emotions ( like a landmine being set off ! ) ofc these are typically a result of mental illness so many people who are apart of the jirai subculture normally have some sort of mental illness

normally it is associated with behavoirs such as self harm, drug abuse, sw, types of eating disorders but not every jirai takes part in these and not every jirai only takes part in these ! there is no one size fits all kind of jirai !

ofc people often like to paint us as the ' dark side of jirai kei ' which is a little silly to me as thats literally what jirai is ! jirai has a strong relation to the dark girly kei fashion but wearing dark girly kei ≠ being jirai

[reasonsforhope]

"People living with diabetes might have a new hope. Scientists have tested a new drug therapy in diabetic mice, and found that it boosted insulin-producing cells by 700% over three months, effectively reversing their disease.

Beta cells in the pancreas have the important job of producing insulin in response to blood sugar levels, but a hallmark of diabetes is that these cells are either destroyed or can’t produce enough insulin. The most common treatment is regular injections of insulin to manage blood sugar levels.

But a recent avenue of research has involved restoring the function of these beta cells. In some cases that’s started with stem cells being coaxed into new beta cells, which are then transplanted into patients with diabetes. Researchers behind this kind of work have described it as a “functional diabetes cure.”

Now, scientists at Mount Sinai and City of Hope have demonstrated a new breakthrough. Previous studies have mostly involved growing new beta cells in a lab dish, then transplanting them into mice or a small device in humans. But this new study has been able to grow the insulin-producing cells right there in the body, in a matter of months.

The therapy involved a combination of two drugs: one is harmine, a natural molecule found in certain plants, which works to inhibit an enzyme called DYRK1A found in beta cells. The second is a GLP1 receptor agonist. The latter is a class of diabetes drug that includes Ozempic, which is gaining attention lately for its side effect of weight loss.

The researchers tested the therapy in mouse models of type 1 and 2 diabetes. First they implanted a small amount of human beta cells into the mice, then treated them with harmine and GLP1 receptor agonists. Sure enough, the beta cells increased in number by 700% within three months of the treatment. The signs of the disease quickly reversed, and stayed that way even a month after stopping the treatment.

“This is the first time scientists have developed a drug treatment that is proven to increase adult human beta cell numbers in vivo,” said Dr. Adolfo Garcia-Ocaña, corresponding author of the study. “This research brings hope for the use of future regenerative therapies to potentially treat the hundreds of millions of people with diabetes.”

The results are intriguing, but of course being an animal study means there’s still much more work to be done before it could find clinical use. So far, harmine alone has recently undergone a phase 1 clinical trial in humans to test its safety and tolerability, while other DYRK1A inhibitors are planned for trials in humans next year.

Perhaps most importantly, the team will soon experiment with combining beta-cell-regenerating drugs with others that modulate the immune system. Ideally this should help overcome a major hurdle: the immune system will continue attacking new beta cells as they’re produced.

The research was published in the journal Science Translational Medicine."

-via New Atlas, July 14, 2024

[darthkote]

hell nah star wars got me researching military tactics for creative purposes (fanfiction)

[m1dylobotomy]

shout to all the therians with "weird", barely studied and extinct theriotypes btw. you guys are so cool I will forever love you