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Living room

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Beautiful winter days in Aurora, Colorado. 🏔

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Diabetes is a condition in which the body produces too little or no insulin. Diabetics thus depend on an external supply of this hormone via injection or pump. Researchers led by Martin Fussenegger from the biosystems science and engineering department at ETH Zurich in Basel, Switzerland want to make the lives of people with diabetes easier and are looking for solutions to produce and administer insulin directly in the body. One such solution the scientists are pursuing is enclosing insulin-producing designer cells in capsules that can be implanted in the body. To be able to control from the outside when and how much insulin the cells release into the blood, researchers have studied and applied different triggers in recent years: light, temperature, and electric fields. Fussenegger and his colleagues have now developed another, novel stimulation method: they use music to trigger the cells to release insulin within minutes. This works especially well with “We Will Rock You,” a global hit by British rock band, Queen. To make the insulin-producing cells receptive to sound waves, the researchers used a protein from the bacterium E. coli. Such proteins respond to mechanical stimuli and are common in animals and bacteria. The protein is located in the membrane of the bacterium and regulates the influx of calcium ions into the cell interior. The researchers have incorporated the blueprint of this bacterial ion channel into human insulin-producing cells. This lets these cells create the ion channel themselves and embed it in their membrane.

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Crested Butte, Colorado

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Downtown Crested Butte

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On the way to Gunnison, Colorado.

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Steamboat Springs, Colorado

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Georgetown, Colorado

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How to use InDesign's Level 2 Number Formatting (1.1, 1.2, etc.)

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Inside The Music Academy, Santa Barbara

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The Music Academy, Santa Barbara

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Hotel Milo and its free bike rentals, Santa Barbara

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Santa Barbara Botanic Gardens

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A beautiful baby shower in Castle Rock, Colorado. 🌷🌲

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pinks and blues

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