#Alendron

[sheirukitriesfandom]

Been having some strong Tyranny feelings lately so have a quick, sloppy doodle of Alendron during the game, mainly because that's when he's not wearing his ridiculously over the top braids. Looking at it now, his jaw should probably be a bit slimmer but eh, can't be bothered to redraw him now...

[how-expensive-is-generic]

How Expensive Is Alendronate Alendronic Acid Fosamax

The cost of Alendronate, commonly known as Fosamax, varies depending on factors such as dosage strength, quantity, and location. Generally, it falls into the category of moderately priced medications, with both brand-name and generic versions available. Patients may find cost-saving options through generic alternatives or patient assistance programs. It's advisable for individuals to consult their healthcare provider and explore different pharmacies to find the most affordable option for their specific needs.

Alendronate Sodium / Alendronic Acid 10 mg Tablet (Generic of FOSAMAX)

120 Tablets | US$ 53 US$ 48 | Save 9 % | Buy Now

240 Tablets | US$ 103 US$ 94 | Save 3 % + 9 % | Buy Now

480 Tablets | US$ 201 US$ 183 | Save 5 % + 9 % | Buy Now

960 Tablets | US$ 394 US$ 359 | Save 7 % + 9 % | Buy Now

Alendronate Sodium / Alendronic Acid 35 mg Tablet (Generic of FOSAMAX)

20 Tablets | US$ 68 US$ 62 | Save 9 % | Buy Now

40 Tablets | US$ 131 US$ 119 | Save 3 % + 9 % | Buy Now

80 Tablets | US$ 257 US$ 234 | Save 5 % + 9 % | Buy Now

160 Tablets | US$ 503 US$ 458 | Save 7 % + 9 % | Buy Now

Alendronate Sodium / Alendronic Acid 70 mg Tablet (Generic of FOSAMAX)

40 Tablets | US$ 59 US$ 53 | Save 9 % | Buy Now

80 Tablets | US$ 114 US$ 103 | Save 3 % + 9 % | Buy Now

160 Tablets | US$ 222 US$ 202 | Save 5 % + 9 % | Buy Now

320 Tablets | US$ 435 US$ 396 | Save 7 % + 9 % | Buy Now

[mcatmemoranda]

I have a pt who saw orthopedics and had a DEXA scan done. She has osteoporosis. Recommendations: Fosamax x2 years in addition to conservative tx with adequate Ca2+ and vitamin D intake of 1200 mg qd and 2000 U qd respectively; weightbearing and resistance exercises; PT; repeat DEXA in 2024.

Fosamax = alendronate

[drpedi07]

Alendronate Drug

Medical information for Alendronate on Pediatric Oncall including Mechanism, Indication, Contraindications, Dosing, Adverse Effect, Interaction, Renal Dose, Hepatic Dose.

[pharmaffiliatesanalytics]

CAS No : 121268-17-5 | Product Name : Alendronate Sodium Trihydrate - API | Pharmaffiliates

Buy highly pure Alendronate Sodium Trihydrate - API, CAS No : 121268-17-5, Mol.Formula : C4H18NNaO10P2, Mol.Weight : 325.12, from Pharmaffiliates. Login as registered user for prices, availability and discounts.

[moneypuzzleexchanger]

What would alendronate sodium look like as an anime girl ?

[bluewindfall]

3 good things

Talked to a really funny patient today. I got to prescribe him alendronate! *O * well technically my preceptor did haha

It's almost the end of week 3, which means I'm halfway through this rotation

Randomly remembered something important OTL

[ihrvietnam]

Thuốc Alendronate có tác dụng điều trị bệnh loãng xương do mãn kinh, suy tuyến sinh dục và sử dụng steroid dài hạn. Thông thường thuốc này sẽ được chỉ định khi mất xương nghiêm trọng, bệnh nhân có nguy cơ cao bị gãy xương do loãng xương. Ngoài ra thuốc còn được sử dụng trong điều trị bệnh Paget về xương.

[yourfirstideas]

Unveiling the Advantages of Fosamax Generic: Essential Insights You Must Check Out

In an intriguing post on Borderfree Health's blog, a new perspective has been provided on Fosamax Generic, a popular medication for bone conditions. It's filled with critical information that particularly resonates with patients grappling with Osteoporosis and Paget's disease, and is well worth the read.

A Closer Look at Fosamax Generic

Fosamax Generic, or Alendronate Sodium, aims to slow bone loss while improving bone mass. As the post explains, it ultimately helps prevent fractures. Fosamax Generic operates by altering bone formation and breakdown within the body. It's beneficial to anyone looking for a convenient alternative to traditional Fosamax, as it's just as effective.

The Advantages of Fosamax Generic

The more you delve into the blog post, the clearer the advantages of Fosamax Generic become. It's not just about the cost-effectiveness; the attraction extends to improved bone health, decreased risk of bone fractures, and reduced bone pain. These benefits make managing Osteoporosis and Paget's disease exponentially easier.

Making an Informed Decision

Patient education is crucial when it comes to medication like Fosamax Generic. This informative post illuminates potential side effects, offers dosing instructions, and guides on storage and disposal. Consequently, users are equipped to make an informed decision about their treatment plan.

MyFirstIdeas recommends this blog for the insight it provides, demystifying a complex subject and making it accessible to all.

[anthonypaulh]

GETTING my TEETH into ITP and DENTAL TREATMENT

Before my purple journey started in 2006 a routine dental appointment would usually be completely straightforward, until then I had never really given much thought to what ITP sufferers should do in respect of such matters. 

Would ITP make any difference to my dental treatment ? What should I tell my dentist about my illness, my medication, my current and future treatment ? Did he need to know ? Why did he need to know ? Could he treat me as a normal patient ? Could he treat me at all ? 

For most people the merest hint of a dental appointment usually sets the collies wobbling. For some it's the buzzing of the drill, for others it's the smell of antiseptic or the taste of the mouth wash. Whatever turns us off, dental appointments are not much fun. 

Luckily I have always had excellent treatment from my dentist. I can't say that a visit to my dentist has ever held any concerns at all. I guess I'm lucky in this respect. So a visit to my dentist as an ITP patient wouldn’t  be any different, would it ?

Well, er, yes actually, it's very different. Just to make me slightly anxious I had heard that a number of ITP patients indicated that they had great difficulty in finding a dentist who had any idea what ITP actually was. Surely things were not this bad ? It was not Victorian England where some people had wooden false teeth and some did DIY dentistry with pliers and string tied to door handles. Hard times indeed. 

The importance of getting regular dental checks is so important whether or not you have ITP but once under the purple influence it becomes even more vital. The phrase prevention rather than cure always comes to the fore when thinking about dental checks but with ITP it is absolutely imperative.

The last thing any of us with ITP needs is to have intrusive dental treatment, which is obviously going to be more difficult if we have a low or fluctuating platelet count. So by getting checked regularly and making sure we keep to good daily routines for oral hygiene, hopefully we can avoid treatment for things like fillings, gum disease and even extractions.

I knew that I had to tell my dentist that I had ITP.  I had to advise him what treatment I had received, what drugs I had been taking , what my latest platelet count was and what treatment regime I was gong to continue with. I knew all this because I had obtained a really useful leaflet from the ITP Support Association. It was very soberly entitled... Protocol for dentists treating patients with Thrombocytopenia. A protocol sounded like something the UN would have drawn up.  But nevertheless it was extremely helpful and I gave a copy to my dentist at my appointment.  

At the dental appointment, as ever, my dentist made things as easy as proverbial pie. He  is just very good at what he does. He's so professional, well informed, up to date with all the latest technology and information (He didn't even pay me to say any of that ! )  I told him that since we'd last met I'd been diagnosed with something called ITP.  Just like everyone else I’d told about my ITP, I thought he'd say something along the lines of ...... Well you don't look ill, I've never heard of it but I'm sure you'll be fine. 

What he actually said was that although he didn't have any other patients with ITP, he'd heard of it. He would treat me in a similar way to a haemophiliac, although he realised that there were many, many differences. He switched on his laptop and we looked up ITP. I'd given him my stodgily named Protocol for dentists leaflet already but he also looked up the ITP Support Association website there and then.

He took notes as I told him my purple history to date. He recorded details of my drugs...Prednisolone, Omeprazole, Alendronic Acid, Rituximab, Mycophenolate Mofetil, platelet count history, current treatment regime, name and contact details of my specialist and any other medical history of relevance.

I didn't have any other medical history apart from ITP so , that was pretty much that. Drama over, we just needed to do the dental bit. Just open wide, say cheese and hope for the best !

It may seem obvious that our dentist needs to know our platelet count. If any treatment is needed, especially an extraction, a platelet count under 50 may preclude that treatment from being carried out. 

If you are going to have any treatment it is sometimes necessary to get a blood test to check your platelet count before undergoing that treatment and with some people it may also be necessary to consult with your ITP specialist/haematologist. 

Advising our dentists of what medication we are currently taking and have taken for the last 12 months is also vital. Any drugs the dentist uses to anaesthetise us for example, may clash with any medications we have taken for our ITP or any other medical condition for that matter. 

Another problem is that should we encounter any pain following any dental interventions the only painkillers we can take are Paracetamol. ITP sufferers must avoid Aspirin or Ibuprofen. Having purple in your life gives you so many things to think about. 

For further information on all things ITP the following links are to the most reliable and up to date sources - 

The ITP Support Association - www.itpsupport.org.uk 

The Platelet Disorder Support Association - https://www.pdsa.org 

ITP Australia - https://itpaustralia.org.au/ 

[sheirukitriesfandom]

9 and 13 for the physicality/characterization ask for Alendron (or whoever else you'd like)?

Huhu, thanks for the ask and sorry for the late answer. Number 9 led me down a research rabbithole and I learned some very interesting things about blind people and body language + facial expressions, knowledge I used to cobble together how I think Al would act.

9. How likely are they to use body language rather than words to express discomfort and other emotions?

Alendron doesn't rely much on body language (for communication) apart from natural reactions like yawning or flinching when getting startled. 

Purposefully making eye contact is impossible for him, so that's off the table.

He wasn't born blind and had some time to pick on conventional facial expressions or gestures, however, employing them now feels less like authentically expressing something and more like mimicking what that expression should be. He also can't check what nonverbal reactions he receives in turn, so he prefers to be direct. 

Alendron does sometimes frown or smile but those facial movements are often an automatic reaction rather than a means of communication and typically don't last long.

Also, he usually carries a cane or a staff so hand gestures are often minimal. He does, however, quickly tip his cane whenever his patience wears short.

13. What trait immediately draws them to other people? 

Politeness and good manners. I can't stress enough how much of a culture shock joining the court and later being part of the conquest was for him. At home, he was used to being pampered and nobody would dare to be rude to him. The easiest way of getting into Alendron’s good graces is to be a cultured, well-mannered, individual sucking up to him. Al loves having his ego stroked. 

Cleanliness and orderliness. Alendron has to rely on his other senses and thus can't stand when that leads him to unpleasant places. He particularly hates the sensation of thick dust against his fingers. He also can't stand people who stink (which is why he keeps Killsy at a distance. If only deodorant or air freshener existed on Terratus…).

A dirty sense of humour. Although Al sees himself above such frivolities, he has a pretty raunchy sense of humour. He himself would never make jokes of that nature (unless you get him drunk, psst) but he loves it when other people tell such jokes and will always snicker at them. His stance on Verse and Eb is basically:

"Goodness gracious, you're horrible, vulgar boors… Would you care to tell another joke?" 

[backlinkdem13]

Bone-modifying drugs

Prostate cancer patients face a significant problem with their bone health. Hormonal therapy can either cause or exacerbate bone conditions like osteoporosis and osteoopenia. The risk of fractures should be assessed for prostate cancer patients receiving ADT for non-metastatic disease. The most widely recognized method for finding an individual’s gamble is with a double energy X-beam absorptiometry (DEXA) sweep to quantify the strength of the bones. Treatment should be given to those who are found to be at a high risk for a fracture. Bone-changing medications that can be utilized in this present circumstance incorporate denosumab (Prolia, Xgeva), zoledronic corrosive (Reclast, Zometa), alendronate (Fosamax), risedronate (Actonel), ibandronate (Boniva), and pamidronate (Aredia). Talk to your doctor about when to take these medications and which is best for you based on your situation because they can have side effects.

In patients who do not currently have evidence of bone metastases, it has not been demonstrated that bone-modifying medications can stop the spread of prostate cancer to the bone.

Patients with prostate cancer that has spread to the bone always run the risk of developing bone issues like fracture, pain, and compression of the spinal cord. These are known as “events related to the skeleton.” At the point when prostate disease has spread to bone and has additionally become impervious to ADT (see “Metastatic maiming safe prostate malignant growth” underneath), bone-adjusting medications might be prescribed to decrease the gamble of these issues. In particular, denosumab or zoledronic corrosive can be given once each month to decrease that gamble.

Dr. Amit Ghosh is one of the best urologist and robotics uro-surgeon in Kolkata. After his return from the UK, he has been associated with various institutions including Wockhardt Hospital and Kidney Institute, Woodlands Hospital, Kothari Medical Center and Anandalok Hospital. Currently he is dedicated to his service to Apollo Gleneagles Hospitals, Kolkata. Currently he has developed a very well established and robust Urological presence in the campus of Apollo Gleneagles Hospitals, Kolkata. The practice takes care of all fundamental general Urological procedures, a vast multi-disciplinary Uro Oncology specialty, and also a comprehensive diagnostic and uro health check-up facility.

[singh-a]

Alendronate induces skeletal alterations in the chicken embryonic development model

http://dlvr.it/SvT7Nx

[ebd-updates]

Alendronate induces skeletal alterations in the chicken embryonic development model

http://dlvr.it/SvT371

[mnnour20]

أفضل علاج ل هشاشة العظام

هو تخفيف الوزن الأول ف العلاج و الثاني ممارسه الرياضة مهم كان سنك كبير او صغير

و لو مش قادر

يبقي المشي يوميا لمده ساعة

بيقوي العظام

الثالث عمل حجامة عند متخصص و ب كاسات خاصة ب المريض فقط دون أستخدام كاسات مريض اخر لأنه تنقل العدوي

الحجامة كما أوصى رسولنا الكريم ف الشهر العربي أفضل أيام ١٣/١٤/١٥

الحجامة تكرر

حتي الشفاء

الحجامة للقولون

لخشونة الركب و الم الجسم و خشونه الرقيه

لجميع للإلم و الأمراض

و هي عن طريق كاسات خاصة ل المريض

تسحب الدم الفاسد من الجسم

و ف حاجة كمان التبرع ب الدم مفيد جدا بيحدد الدورة الدموية

ثالثا عن بعض تجارب للأخرين

إن الفوسفونات الثنائية هي الخيار الأول عادةً لعلاج هشاشة العظام. ومن ضمنها: أليندرونيت (فوساماكس)، قرص أسبوعيًا ريزيدرونيت (أكتونيل)، قرص أسبوعيًا أو شهريًا

يحتوي دواء فوساماكس على مادة أليندرونات Alendronate. تنتمي هذه المادة للمجموعة الدوائية التي تعرف باسم بايفوسفونات bipohosphonate والتي تتميز بقدرتها على إيقاف تكسير بنية العظام بشكل غير مباشر عن طريق تعطيل عمل ناقضات العظام. حيث ترتبط مادة اليندرونات بالكالسيوم الموجود في العظم بشدة وتمنع امتصاصه بواسطة ناقضات العظام، مما يحفظ بنية العظام القوية ويمنع تعرضها للكسور. وبسبب هذه الخاصية في دواء فيوساماكس فإنه يستخدم للوقاية او للعلاج من الكسور المصاحبة لهشاشة العظام.

دواعي الإستعمال :

يستعمل دواء فوساماكس في الحالات التالية:

– الوقاية من مرض هشاشة العظام عند النساء.

– علاج هشاشة العظام والكسور الناتجة عنها.

– علاج هشاشة العظام الناتجة عن العلاج لمدد طويلة بأدوية الكورتيزون.

– زيادة كثافة وكتلة العظام عند الرجال الذين يعانون من هشاشة العظام.

– علاج مرض باجيت paget’s disease.

الجرعات وكيفية الإستعمال:

ملحوظة هامة: من المهم جدا ألا يتم إستخدام هذا الدواء إلا تحت إشراف ومتابعة طبية دقيقة وفقط إذا إستدعت حالة المريض الصحية ذلك.

يجب تناول العلاج على معدة خالية وعلى الاقل قبل الاكل او تناول اية اطعمة او ادوية بنصف ساعه على الاقل ويجب شرب الكثير من الماء اثناء تناول الجرعة وبعدها مباشرة.

تختلف جرعة العلاج حسب الحالة التي يتم علاجها، بوجه عام فإن:

– علاج هشاشة العظام في النساء: قرص 70 مجم/ كل إسبوع.

– علاج هشاشة العظام في الرجال: نصف قرص 35 مجم/ كل اسبوع.

– الوقاية من هشاشة العظام: نصف قرص 35مجم / كل إسبوع.

– علاج مرض باجيت: 40 مجم/ يوميا لمدة 6 أشهر.

إحتياطات خاصة:

لضمان السلامة وتلافي الآثار الجانبية قدر المستطاع يجب مراعاة الاحتياطات التالية.

– عدم تناول فوساماكس قبل النوم، بدلا من ذلك يجب تناوله عقب الإستيقاظ.

– يجب تناول الدواء على معدة خالية ومعه كمية كافية من الماء او السوائل لضمان اعلى قدر من الإمتصاص.

– يجب عدم الإستلقاء او الرقود بعد تناول الجرعة ولمدة نصف ساعه الى ساعه على الاكثر وذلك لتفادي حدوث إلتهابات في المريء.

– يجب التأكد من تناول جرعات كالسيوم وفيتامين د كافية لضمان فاعلية العلاج.

– يجب عمل إختبارات دورية للدم لمستوى الكالسيوم حيث يتسبب العلاج لمدد متصلة بدواء فوساماكس في إنخفاض نسبة الكالسيوم في الدم.

– يجب التوقف عن تناول الدواء في حالة ظهور مشاكل شديدة بالبلع او الام بالمريء او فم المعدة.

– يجب الاهتمام الفائق بصحة الفم والأسنان حيث أنها قد تتضرر من العلاج المستمر بدواء فوساماكس وينبغي متابعة طبيب الاسنان بصفة دورية اثناء فترة العلاج.

محاذير الإستعمال:

يتسعمل فوساماكس بحرص مع الحالت التالية:

– حالات القصور الكلوي.

– التاريخ المرضي السابق لمشاكل الجهاز الهضمي مثل قرح المعدة و الإثنى عشر او التهابات المريء.

– مشاكل الجهاز الهضمي العلوي الحالية: إلتهابات المريء، اضطرابات المعدة، الإرتجاع، القرحة المعدية النشطة او قرحة الإثنى عشر.

– إضطرابات الغدة الجاردرقية.

– حالات نقص فيتامين D .

موانع الإستعمال:

– الأطفال والمراهقين تحت سن 15 عاما.

– فرط الحساسية للمادة الفعالة.

– الحساسية لسكر اللاكتوز.

– الحمل والرضاعة الطبيعية.

– حالات ضيق المريء أو اي عيوب خلقية او إصابات بالمريء.

– المصابين بنقص الكالسيوم.

– الحالات التي لا تستطيع البقاء واقفة لمدة لا تقل عن نصف ساعه.

الإستعمال مع الحمل والإرضاع:

لايسمح بإستخدام دواء فوساماكس أثناء الحمل حيث أنه يندرج ضمن الفئة C وفق تصنيف الهيئة الأمريكية للغذاء والدواء FDA وبناءاً عليه فإن الدراسات النظرية تشير لخطورة استخدامه خلال الحمل لأنه سيسبب أضراراً جسيمة وتشوهات بالجنين وكذلك للأم.

لا توجد دراسات كافية عن إستخدام دواء فوساماكس خلال فترة الرضاعه ومن غير الملعوم ما إذا كان الدواء يتم إفرازه في اللبن أم لا، ولذلك لاينصح بإستمعمال فوساماكس أثناء فترة الرضاعه.

الآثار الجانبية المحتملة:

كأي دواء آخر، فإن إستعمال هذا الدواء قد يسبب مجموعة من الآثار الجانبية التي قد يظهر بعضها او أغلبها عند بعض وليس بالضرورة كل المرضى. تتضمن الآثار الجانبية

آثار جانبية شائعة:

– صداع.

– اضطراب الجهاز الهضمي: إسهال، إمساك، عسرالهضم، انتفاخ، إرتجاع العصارة المعدية، مغص.

– تقرح المريء.

– صعوبة البلع.

– آلام بالمفاصل، والعضلات.

آثار جانبية أقل شيوعا:

هذه الأعراض قد تحدث بنسبة بسيطة عند بعض المستخدمين ومنها:

– غثيان وقيء.

– إلتهاب المريء و المعدة.

– قرح وثقب بالمريء أوالمعدة.

– دم بالبراز يسبب إسوداد البراز او مايعرف باسم melena.

– فرط التحسس بالجلد مع حكة شديدة، إحمرار و تورم.

– إالتهاب القزحية.

– تآكل عظام الفك.

– نقص نسبة الكالسيوم في الدم ومايترتب عليها من إحساس بالتنميل او الخدر في الأصابع، التشنجات والشد العضلي.

– إرهاق وضعف عام.

– تورم باليدين والقدمين والمفاصل.

– تساقط الشعر.

– كسر في منطقة التحام رأس عظمة الفخذ بباقي جسم العظمة.

التداخلات الدوائية:

لضمان الإمتصاص الجيد للدواء يجب ألا يؤخذ الا على معدة خالية مع الكثير من الماء، على الا يتم تناول اي اطعمة او ادوية اخرى قبله او بعده الا بفاصل زمني 30 دقيقة على الاقل.

** الادوية التالية لا يجب تناولها مع فوساماكس الا بفاصل زمني كاف لا يقل عن 30 دقيقة وذلك لأن تناولها بالتزامن مع فوساماكس يؤدي لضعف امتصاصه وبالتالي عدم فعاليته في العلاج:

– مضادات الحموضة.

– المكملات الغذائية التي تحتوي على المعادن مثل الكالسيوم والحديد والمغنسيوم، او الزنك.

– الملينات التي تحتوي على المغنسيوم.

** الادوية التالية لا يجب إستعمالها اثناء التداوي بدواء فوساماكس لأنها قد تزيد من فرص حدوث قرح المعدة او الامعاء او نزيف الجهاز الهضمي:

– الاسبرين.

– البروفين.

– مضادات الإلتهاب غير السترويدية عموماً.

** ينبغي الحرص حين تنالو الادوية التالية حيث انها تزيد من فرص حدوث نقص الكالسيوم في الدم عند استعمالها مع فوساماكس:

– المضادات الحيوية من فئة أمينوجليكوزيد.

التخزين:

يحفظ في مكان جاف وبعيداً عن الضوء.

[nursingscience]

List of Common Drug Side Effects

11. Esophageal Damage

May occur with a wide-range of drugs including aspirin, bisphosphonates (such as alendronate), doxycycline, potassium chloride, quinidine, and vitamin C.

▪️Prevention and management strategies:

1. Take all medicines while upright and swallow with a glass of water

2. Avoid lying down soon after taking a medicine

3. For some medicines, recommended advice includes remaining upright for 30 minutes after taking

4. Avoid irritating foods such as citrus and alcohol

5. Talk to your doctor about the possibility of switching to a different medication.