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#Coronavirus Patients In US
thoughtportal · 7 months
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Opinion Here’s how to get free Paxlovid as many times as you need it
When the public health emergency around covid-19 ended, vaccines and treatments became commercial products, meaning companies could charge for them as they do other pharmaceuticals. Paxlovid, the highly effective antiviral pill that can prevent covid from becoming severe, now has a list price of nearly $1,400 for a five-day treatment course.
Thanks to an innovative agreement between the Biden administration and the drug’s manufacturer, Pfizer, Americans can still access the medication free or at very low cost through a program called Paxcess. The problem is that too few people — including pharmacists — are aware of it.
I learned of Paxcess only after readers wrote that pharmacies were charging them hundreds of dollars — or even the full list price — to fill their Paxlovid prescription. This shouldn’t be happening. A representative from Pfizer, which runs the program, explained to me that patients on Medicare and Medicaid or who are uninsured should get free Paxlovid. They need to sign up by going to paxlovid.iassist.com or by calling 877-219-7225. “We wanted to make enrollment as easy and as quick as possible,” the representative said.
Indeed, the process is straightforward. I clicked through the web form myself, and there are only three sets of information required. Patients first enter their name, date of birth and address. They then input their prescriber’s name and address and select their insurance type.
All this should take less than five minutes and can be done at home or at the pharmacy. A physician or pharmacist can fill it out on behalf of the patient, too. Importantly, this form does not ask for medical history, proof of a positive coronavirus test, income verification, citizenship status or other potentially sensitive and time-consuming information.
But there is one key requirement people need to be aware of: Patients must have a prescription for Paxlovid to start the enrollment process. It is not possible to pre-enroll. (Though, in a sense, people on Medicare or Medicaid are already pre-enrolled.)
Once the questionnaire is complete, the website generates a voucher within seconds. People can print it or email it themselves, and then they can exchange it for a free course of Paxlovid at most pharmacies.
Pfizer’s representative tells me that more than 57,000 pharmacies are contracted to participate in this program, including major chain drugstores such as CVS and Walgreens and large retail chains such as Walmart, Kroger and Costco. For those unable to go in person, a mail-order option is available, too.
The program works a little differently for patients with commercial insurance. Some insurance plans already cover Paxlovid without a co-pay. Anyone who is told there will be a charge should sign up for Paxcess, which would further bring down their co-pay and might even cover the entire cost.
Several readers have attested that Paxcess’s process was fast and seamless. I was also glad to learn that there is basically no limit to the number of times someone could use it. A person who contracts the coronavirus three times in a year could access Paxlovid free or at low cost each time.
Unfortunately, readers informed me of one major glitch: Though the Paxcess voucher is honored when presented, some pharmacies are not offering the program proactively. As a result, many patients are still being charged high co-pays even if they could have gotten the medication at no cost.
This is incredibly frustrating. However, after interviewing multiple people involved in the process, including representatives of major pharmacy chains and Biden administration officials, I believe everyone is sincere in trying to make things right. As we saw in the early days of the coronavirus vaccine rollout, it’s hard to get a new program off the ground. Policies that look good on paper run into multiple barriers during implementation.
Those involved are actively identifying and addressing these problems. For instance, a Walgreens representative explained to me that in addition to educating pharmacists and pharmacy techs about the program, the company learned it also had to make system changes to account for a different workflow. Normally, when pharmacists process a prescription, they inform patients of the co-pay and dispense the medication. But with Paxlovid, the system needs to stop them if there is a co-pay, so they can prompt patients to sign up for Paxcess.
Here is where patients and consumers must take a proactive role. That might not feel fair; after all, if someone is ill, people expect that the system will work to help them. But that’s not our reality. While pharmacies work to fix their system glitches, patients need to be their own best advocates. That means signing up for Paxcess as soon as they receive a Paxlovid prescription and helping spread the word so that others can get the antiviral at little or no cost, too.
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truth4ourfreedom · 3 months
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THE BENEFITS OF IVERMECTIN. IF YOU HAVE CANCER, FREQUENT COLD OR INFECTIONS, MUSCLE SHRINKAGE, CARDIAC ISSUES, CROHNS, HERPES, ETC.
The study was published in the Cureus Journal of Medical Science.  LET'S TALK ABOUT IVERMECTIN 1 – Ivermectin prevents the damage caused to RNA Vaccines.  2 – Ivermectin blocks the entry of Spike Protein into cells.  So, if the person was vaccinated with COVID, they have hope, they have a way to treat themselves through Ivermectin.  3 – Ivermectin is a treatment after Covid and after vaccination, it is an effective medicine in all phases of Covid 19, even before entering the cell, Ivermectin already destroys the virus in the blood.  It only has beneficial effects and no harmful effects in the treatment of the coronavirus.  4 – Ivermectin has a very powerful anti-inflammatory action against Coronavirus.  5 – Ivermectin has a powerful action for traumatic and orthopedic injuries, it strengthens muscles and has no side effects like corticosteroids.  6 – Ivermectin treats autoimmune ailments such as: rheumatoid arthritis, ankylosing spondylitis, fibromyalgia, psoriasis, Crohn's disease, allergic rhinitis.  7 – Ivermectin reduces the frequency of flu and colds.  8 – Ivermectin improves the immunity of cancer patients.  9 – Ivermectin treats Herpes Simplex and Herpes Zoster.  10 – Ivermectin reduces the frequency of sinusitis and diverticulitis.  11 – Ivermectin protects the heart in cardiac overload, in an embolism for example, it prevents cardiac hypoxia because it stimulates the production of basic energy so that the tissue is not destroyed and thus improves cardiac function.  12 – Ivermectin is antiparasitic.  13 – Ivermectin is anti-neoplastic (anti-cancer), it suppresses the proliferation and metastasis of cancer cells, only killing cancer cells and preserving healthy cells, improving the effectiveness of chemotherapy treatment, as it kills cancer cells resistant to chemotherapy, defeating the resistance to multiple chemotherapeutics that tumors develop, and combined with chemotherapy and/or anti-cancer agents, it provides an increase in the effectiveness of these treatments.  14 – Ivermectin is antimicrobial (bacteria and viruses), and increases immunity.  15 – Ivermectin reaches the Central Nervous System and regenerates the nerves.  16 – Ivermectin regulates glucose and insulin metabolism.  17 – Ivermectin regulates cholesterol metabolism.  18 – Ivermectin reduces liver fat in steatose.  19 – Ivermectin protects the liver exposed to insecticides.  20 – Ivermectin attacks the virus wherever it is, regardless of mutations.  21 – Ivermectin serves for the prevention and treatment of coronavirus, surprisingly.  Unproven efficacy is not of Ivermectin, but of vaccines.  22 – Ivermectin, used as a prophylactic agent, was associated with a significant reduction in infection, hospitalization and mortality rates due to COVID-19.  23 - Ivermectin does not attack the liver, since it is not metabolized in it, and if in the intestine, on the contrary, it protects the liver. 
BIG PHARMA DOES NOT WANT YOU TO KNOW THIS.THEY WANT TO SELL YOU THE EXPENSIVE MEDS THEY MAKE BILLIONS ON.
Please read, save and re-blog before Tumblr takes this down.
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bearygentle · 2 years
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booooooo, remember that time a week or so ago when I mentioned being super sick?
well suprise suprise, mom tested positive right around when we all came down w/ symptoms. and just like. didn't bother to mention it I guess
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jeraliey · 11 months
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It's still not just a cold.
"This study showing that severe acute respiratory syndrome coronavirus directly infects coronary artery plaques, producing inflammatory substances, really joins the dots and helps our understanding on why we're seeing so much heart disease in COVID patients," Peter Hotez, MD, professor of molecular virology and microbiology at Baylor College of Medicine in Houston, told Medscape.
Oh, also?
CDC predicts respiratory disease season will be similar to last year
"The CDC said it expects a similar number of respiratory disease cases this year as last year, with 15 to 25 new weekly hospitalizations per 100,000 people."
"As of Friday, nearly 12 million people have gotten the new Covid-19 vaccine since they were authorized last month, according to HHS. That’s millions more than the week prior, but still less than 4% of the US population."
No one is protecting themselves. And no one else will protect you.
Even if you're not worried for yourself....don't be one of the people that carries it to someone else. We're all responsible for the most vulnerable people in our society. (That could be you, by the way.....)
WEAR. YOUR. MASK.
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gatheringbones · 11 months
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[“As computer programs determine how many patients can be profitably squeezed into a day, doctors become tools. Then the actual machines march triumphantly into the wards.
Nurses are now separated from patients by computers on wheels that roll everywhere with them: their bossy robot taskmasters. When you first see a nurse, she or he will likely have eyes on the screen rather than on you. This has dreadful consequences for your treatment, since you become a checklist rather than a person. If you are having a problem unrelated to what is on the screen, some nurses will have a hard time gathering themselves and paying attention. For example, after my first liver procedure my liver drain was improperly attached. This was a serious problem that was easily reparable. Yet although I tried for four days to draw attention to it, I could not get through. It was not on the lists. And so I had a second liver procedure.
When I read my own medical record, I was struck by how often doctors wrote what was convenient rather than what was true. It’s hard to blame them: they are locked in a terrible record-keeping system that sucks away their time and our money. When doctors enter their records, their hands are guided by the possible entries in the digital system, which are arranged to maximize revenue. The electronic medical record offers none of the research benefits that we might expect from its name; it is electronic in the same sense that a credit card reader or an ATM is electronic. It is of little help in assembling data that might be useful for doctors and patients.
During the coronavirus pandemic, doctors could not use it to communicate about symptoms and treatments. As one doctor explained, “Notes are used to bill, determine level of service, and document it rather than their intended purpose, which was to convey our observations, assessment, and plan. Our important work has been co-opted by billing.” Doctors hate all of this.
Doctors of an older generation say that things were better in their time—and, what is more worthy of note, younger doctors agree with them. Doctors feel crushed by their many masters and miss the authority that they used to enjoy, or that they anticipated that they would enjoy when they decided to go to medical school. Young people go to medical school for good reasons, then find their sense of mission exploited by their bosses. Pressured to see as many patients as possible, they come to feel like cogs in a machine. Hassled constantly by companies that seek to pry open every aspect of medical practice for profit, they find it hard to remember the nobility of their calling. Tormented by electronic records that take as much time as patient care, and tortured by mandatory cell phones that draw them away from thinking, they lose their ability to concentrate and communicate. When doctors are disempowered, we do not learn what we need to be healthy and free.”]
timothy snyder, from our malady: lessons in liberty from a hospital diary, 2020
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afeelgoodblog · 1 year
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The Best News of Last Week
��� - Charging Towards a More Electrifying Future
1. The Kissimmee River has been brought back to life—and wildlife is thriving
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The Kissimmee River in Florida was straightened in the 1960s, causing a sharp decline in wildlife and ecological problems. But in the 1990s, a $1 billion restoration project was initiated to restore the river's natural state.
Today, nearly half of the river has been restored, wetlands have been reestablished and rehydrated, and wildlife has returned, including rare and threatened species. Already the biological impact of the project has become clear. As the wetlands have come back, so have the birds.
2. Plastic wrap made from seaweed withstands heat and is compostable
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A cling film made from an invasive seaweed can withstand high temperatures yet is still easily compostable. The material could eventually become a sustainable choice for food packaging.
Scientists started with a brown seaweed called sargassum. Sargassum contains long, chain-like molecules similar to those that make up conventional plastic, which made it a good raw material. The researchers mixed it with some acids and salts to get a solution full of these molecules, then blended in chemicals that thickened it and made it more flexible and pliable.
3. An Eagle Who Adopted a Rock Becomes a Real Dad to Orphaned Eaglet
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Murphy, a bald eagle that had been showing fatherly instincts, has been sharing an enclosure with an eaglet that survived a fall from a tree during a storm in Ste. Genevieve. Murphy, his rock gone by then, took his role as foster parent seriously. He soon began responding to the chick’s peeps, and protecting it.
And when, as a test, the keepers placed two plates of food in front of the birds — one containing food cut into pieces that the chick could eat by itself, and another with a whole fish that only Murphy could handle — the older bird tore up the fish and fed it to the eaglet.
4. World's largest battery maker announces major breakthrough in energy density
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In one of the most significant battery breakthroughs in recent years, the world’s largest battery manufacturer CATL has announced a new “condensed” battery with 500 Wh/kg which it says will go into mass production this year.
“The launch of condensed batteries will usher in an era of universal electrification of sea, land and air transportation, open up more possibilities of the development of the industry, and promote the achieving of the global carbon neutrality goals at an earlier date,” the company said in a presentation at Auto Shanghai on Thursday.
This could be huge. Electric jets and cargo ships become very possible at this point.
5. Cat with '100% fatal' feline coronavirus saved by human Covid-19 medicine
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A beloved household cat has made an “astonishing” recovery from a usually fatal illness, thanks to a drug made to treat Covid-19 in humans – and a quick-thinking vet.
Anya​, the 7-year-old birman cat, was suffering from feline infectious peritonitis (FIP), a “100% fatal” viral infection caused by feline coronavirus. That was, until Auckland vet Dr Habin Choi​ intervened, giving Anya an antiviral used to treat Covid-19 called molnupiravir.
6. Kelp forests capture nearly 5 million tonnes of CO2 annually
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Kelp forests provide an estimated value of $500 billion to the world and capture 4.5 million tonnes of carbon dioxide from seawater each year. Most of kelp’s economic benefits come from creating habitat for fish and by sequestering nitrogen and phosphorus.
7. Medical Marijuana Improved Parkinson’s Disease Symptoms in 87% of Patients
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Medical cannabis (MC) has recently garnered interest as a potential treatment for neurologic diseases, including Parkinson's disease (PD). 87% of patients were noted to exhibit an improvement in any PD symptom after starting medical cannabis. Symptoms with the highest incidence of improvement included cramping/dystonia, pain, spasticity, lack of appetite, dyskinesia, and tremor.
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That's it for this week :)
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Buy me a coffee ❤️
Also don’t forget to reblog
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NYT: Cuomo Personally Altered Report Which Understated Nursing Home COVID Deaths by Over 50%, Emails Reveal - Published Sept 19, 2024
By Joseph Feldman
NEW YORk – Former Governor Andrew Cuomo personally altered a state report that significantly underreported the number of nursing home deaths from COVID-19 by over 50%, according to emails cited in a new report.
The New York Times revealed that emails and congressional documents challenge Cuomo’s claim, made during a congressional hearing, that he had no recollection of seeing or reviewing the state Health Department’s report.
In June 2020, Cuomo’s assistant reportedly sent an email to his senior staff with the message, “Governor’s edits are attached for your review,” according to the Times.
Cuomo, who recently testified before the Select Subcommittee on the Coronavirus Pandemic, was not under oath during his testimony but was warned he could face criminal charges for knowingly making false statements.
The former governor’s actions during the early stages of the pandemic have drawn criticism, particularly an order to send elderly COVID-19 patients back to nursing homes, which may have led to as many as 9,000 additional deaths. Cuomo acknowledged he referred to this March directive as “the great debacle” in an email sent to his inner circle.
A July 2020 state Department of Health report downplayed the number of nursing home deaths, a move that a U.S. House committee described as part of a “cover-up.” The House Select Subcommittee on the Coronavirus Pandemic alleged Cuomo’s office had altered the report, but the emails suggest Cuomo was directly involved.
The Times report indicates Cuomo personally added language to the report that placed blame on nursing home staff, visitors, and family members for spreading the virus. During his June questioning by House members, Cuomo claimed he had no recollection of reviewing or editing the report before its release on July 7, 2020.
Although Cuomo is known for avoiding the use of email, the Times noted that none of the emails in question were sent by him.
During a Capitol Hill hearing on September 10, Cuomo’s repeated denials prompted Rep. Mike Lawler (R-NY) to label him a “lying sack of s—t.”
Vivian Zayas, co-founder of Voice for Seniors, whose mother died in a Long Island nursing home after contracting COVID-19, attended the hearing. She accused Cuomo of lying, stating, “If he lied to Congress, he committed a crime. He should definitely be investigated.”
Cuomo’s spokesperson, Rich Azzopardi, responded to the email revelations by insisting that nursing home staff spread the virus, aligning with the findings of the original report. Azzopardi also emphasized that Cuomo cooperated fully with the congressional inquiry and argued that the findings align with CDC guidelines in place at the time.
Cuomo, who stepped down in August 2021 amid sexual misconduct allegations, has been rumored to be considering a run for New York City mayor as current Mayor Eric Adams faces growing scandals.
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meret118 · 1 month
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COVID isn’t just spreading like wildfire through the Olympic Village in Paris — we are undergoing surges across the globe, with the World Health Organization tracking steep rises in infections in 84 countries. After more than four years fighting this thing, it is still knocking us out.
In some parts of the U.S., the amount of COVID is so high that experts are claiming this summer surge is on par with winter waves of the virus. But none of this should be unexpected at this point. This is no longer the “novel” coronavirus that once terrified people with its unpredictability. We know how it behaves, with surges in both summer and winter, and we know how to fight against it — yet our apparent strategy at the moment is to pretend it doesn’t exist at all, even when it swipes us off our feet.
. . .
Deaths aren’t the only concerning metric, of course. Sometimes a COVID infection is asymptomatic, while at other times, the symptoms last for months or years or never fully go away. Patients call this long COVID and public health experts have described it as a mass disabling event. Lyles isn’t just lucky he won a bronze medal — he’ll be lucky if he doesn’t experience months of headaches, lung issues or extreme fatigue that never goes away.Yet long COVID is rarely factored into discussions about this pandemic, even when kids get it. Instead, it’s treated as if infections are merely a mild cold at this point.
. . .
Millions of patients can attest that COVID is anything but mild — and it's definitely not the flu. The SARS-CoV-2 virus can worm its way into nearly every part of our bodies, trashing our immune system and damaging our organs. We tend to think of the disease as a respiratory problem, given all the coughs and sniffles it produces, but it’s really more of a vascular disease, impacting any system that relies on blood vessels. That can include damage to the brain, which can manifest in symptoms like long-term cognitive impairment and Parkinson’s disease.
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I was absolutely appalled he knew he had covid, but was out there without a mask hugging people. Incredibly fucking selfish.
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felinefractious · 4 months
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hi! love your blog, i love getting to see all these cool cat colors i didnt even know were a thing LOL like i didn’t know there was such a thing as lilac or cinnamon but theyre so pretty.
ive been looking into getting a ragdoll in the future, the ones i have met have been the sweetest cats and they’re so pretty.
ive been doing research into possible health concerns they can have, and all im really seeing is the same things your typical random little guy could have when improperly cared for and things like that. kidney disease while on a bad diet, issues with hairballs when not brushed and groomed properly due to being long haired, etc. ive seen a few places say that they’re more prone to respiratory issues and heart disease, but the latter also seems to be something that breeders work to make sure their cats are safe from? at least in my research.
i guess im basically just wondering if you know anything else that can affect ragdolls specifically, or if there’s anything horribly unethical that’s totally swept under the rug or hidden about them! additional things to research and places to look would be appreciated, i never know where to research stuff like this reliably and you seem to know where to find some good info and stuff on cat breeds :)
thank you in advance for any help you can give, i hope have a good day!!
I’m glad you enjoy the blog and are learning about some new colors!
Ragdolls are definitely cool cats and they’re a pretty health breed, one of the major things to be mindful of is that this assessment only applies to well-bred individuals from good breeders.
Common breeds mean a lot of breeders which, unfortunately, also means a lot of scammers and bad breeders.
And the Ragdoll is a very common breed so there are a lot of not so good breeders out there… and the temperament and health of these backyard bred cats is a gamble, one that can end in heartbreak.
Now with that warning out of the way the big thing to worry about with the breed is Hypertrophic Cardiomyopathy. Fortunately the mutation responsible for this condition in the breed has been identified and can be tested for. Staying on top of heart health is an absolute must for a good breeder, this means regular echocardiogram’s as well as DNA testing.
The other big ones are Polycystic Kidney Disease and Progressive Retinal Atrophy, both of which can be tested for. These are common inherited disorders in the purebred population, you’ll have a hard time finding a breed which neither of these have been documented in.
Mucopolysaccharidosis VI is a storage disease that has been documented in the Ragdoll breed but it can be tested for and I’m not sure how common it is in current breeding populations.
A breeder shouldn’t cut corners when it comes to health testing, there are several commercially available tests which look for a wide variety of inherited disorders. Optimal Selection is becoming increasingly widely used, although personally I would feel most comfortable with testing submitted through somewhere like UC Davis.
But HCM is the big big one because heart disease is a silent killer. With the other conditions clinical symptoms will be apparent but a cat with HCM could appear normal and you wouldn’t know without testing. And remember - not all cardiac cases will have a heart murmur, either!
The other thing to keep in mind with Ragdolls is they seem to be more prone to developing Feline Infectious Peritonitis. This one is a little more complicated.
FIP occurs due to mutations in the feline coronavirus, which is a common viral infection in cats. Until recently FIP was considered nearly 100% fatal but thanks to Dr. Niels Pederson we now have a promising cure. One of our patients was actually one of the original study cats and has been doing well all this time, she’s amazing to work with - like a piece of living history!
One of the big problems with the treatment is the legality of it… for a long time it was only available through the black market and could easily run you thousands of dollars. Treatment is gradually becoming available through legal venues but it depends on where you live.
Anyways, the point is that we don’t know exactly why these mutations occur in some cats and not others but there’s strong evidence that there’s a genetic component - it’s common for related cats to develop FIP, we’ve seen this multiple times with littermates. We also know that it occurs at a higher incidence in some breeds than others…
And presumably your kitten wouldn’t have been exposed to feline coronavirus at the cattery but it’s not unlikely that they would be exposed at some point in their life given they don’t reside in a bubble… and if or when this happens what are the chances it’ll become the dreaded FIP?
So mitigating this risk when purchasing from a breeder can be a little more complicated… it’s not something I think should turn you off of the breed but it is something to keep in mind - and if you look into a breeder that seems good but has a lot of reviews or reports of their graduate kittens and cats developing FIP? Probably best to keep looking.
I think that’s a pretty good summary on the breed’s health but people are always welcome to chime in!
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darkmaga-retard · 11 days
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The FDA has authorized the use of a new Covid vaccine from Novavax under emergency use authorization even though they have neither licensed nor approved it.
Despite the Novavax vaccine being a more traditional vaccine technology, the listed side effects on the manufacture’s website are very similar to what has been seen from the mRNA shots, including myocarditis, pericarditis and other ‘serious and unexpected’ side effects.
InfoWars reports: The Novavax Covid shot uses a more traditional vaccine technology than the exotic mRNA technology of Pfizer or Moderna, or the exotic viral vector technology of J&J or AstraZeneca. The Novavax vaccine is not a gene therapy. It is very different than the upcoming saRNA self replicating ‘replicon’ Covid vaccine that Japan is set to begin injecting in October.
“The Novavax COVID-19 Vaccine, Adjuvanted (2024-2025 Formula) has not been approved or licensed by FDA, but has been authorized for emergency use by FDA, under an Emergency Use Authorization (EUA) to prevent Coronavirus Disease 2019 (COVID-19) in individuals 12 years of age and older. Refer to the full Fact Sheet for information about the Novavax COVID-19 Vaccine, Adjuvanted,” the Novavax website said. “The EUA of this product is in duration of the COVID-19 EUA declaration justifying emergency use of the product, unless the declaration is terminated, or the authorization is revoked sooner.”
Interestingly, President Joe Biden ended the Covid emergency over a year ago, bringing into question the authenticity of the Covid pandemic ’emergency’ authorization.
Novavax’s Covid vaccine has been available for patients in a number of countries outside the U.S. for a number of years now. It is being billed to Americans as an alternative for those hesitant of taking the exotic modified mRNA novel technology into their bodies.
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kiara-ish · 1 year
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IDOL SOLDIER
Chapter 1
Words: 5k+
Summary: The world is changing yet again. People are turning into flesh biting monsters and with all backs to the walls, every second is a war between life and death. You expected a lot in life but never in your wildest dreams did you expect to meet Kim Seokjin in the middle of an apocalypse.
Pairing: Enlisted Soldier!Seokjin x fem!Reader
Genre: Dystopia | Romance
Rating: series rating - 18+ | chapter rating - 16+
Series Warnings: blood, gore, violence, mentions of abuse, mentions of sexual harrasment, deaths, graphic descriptions, suggestive themes.
Author's Note: This was initially supposed to be a long oneshot but after scrapping my drafts multiple times, I decided to break it into parts for easy reading and smooth writing too. Also, if I blinded you with that horrible cover, I'm really sorry me and graphics don't go well together. I'll fix it whenever I can.
m.list | next ->
Dystopia always was my favourite trope to write. There was something about hopelessness that always had me taking up the pen. I always supposed it was something rather mundane and humane – to be curious of misery and despair. Until one day when the television that I sometimes left on in the evenings when I felt extraordinarily lonely caught my attention.
"...the rapid growth of the virus Z-24 is shocking. The constant spike in the number of affected is fearsome especially because the medium of transfer is yet to be discovered. What is spreading even more terror is the worsening condition of those infected, they have shown signs of insanity and as the specialists have named it – the zombie syndrome. It is becoming very difficult to reassure the crowd of grieving and worried families outside the hospitals and quarantine. Today, we have with us…"
With the said attention having the span matching that of a goldfish, I was distracted by a ping of notification on my phone and zoned out the news. In hindsight, my listening or not listening to the news wouldn't have made much of a difference. But it might have made me prepare better, it might have allowed me to ponder more on zombie syndrome than Kim Seokjin's nearing end of military service.
Apart from the regulation of wearing masks and sanitizing, there wasn't much havoc about the virus so people took it as seriously as they did coronavirus – scared but reassured that it will be fine sooner or later. So like every other patient citizen, I lost my shit when a lockdown was declared simultaneously with a message from my manager announcing the reduction of the travel allowance because of the change in mode of work.
Going off the texts, my social media was flooded with video clips, hazy, distraught – almost like an illegally filmed video. I knew what they would show but did not want to experience the same fervent panic from the night before. I scrolled past most videos until my clumsy fingers accidentally let go of the phone and in the eager grasp of catching it, a video started playing.
A vlogger was speaking in a broken, hushed voice. His words were unclear nor did I have the motivation to be keener in my observation. He was showing pitch darkness and it intrigued me. So instead of scrolling past like I intended, I stayed and tried to scrutinize the scene but to no help — it was all dark.
"Did you hear that?"
The vlogger's voice was suddenly clearer but his question threw me off. It was unnerving. There was an unfamiliar tremor in his voice that made me feel the same fear as him. The dark screen was suddenly not still and the silhouette of a door came into view.
"The sound came from right outside. Should I open the door to see?"
Of course he shouldn't. There could be found some ten thousand horror movies that would tell him that he should not. But he did anyway. There was no foreboding creek as the door opened, some fragments of street light in the distance that looked more ominous than reassuring. It was still silent, eerily like it was a warm summer evening in the countryside where people had nothing to worry about let alone flesh biting horrors.
"There is nothing here. To appreciate my bravery don't be shy in sending gifts and whatever your heart desires at–"
It was so quick I almost missed it and had I been successful at missing it, maybe my heart would be saved.
It wasn't a grand howl and attack. It was just a blink of darkness moving, covering the lights in the distance with the shadow and as the lights became visible again, it was obvious that something had moved. There was no foreshadowing, ominously sidelining; in a wink there was a rustle of clothes and the clang of the camera falling to the floor. It was pitch darkness but the vlogger had left no stone turned in choosing his recording mic.
As the mic stayed on around his mouth, the squelching of blood resonated loudly as the infected tore his neck probably, its heavy breathing and teeth biting into flesh with a small ripping sound like that of soft muslin. A second too late, the man started gurgling on his blood. He had no time to scream, no chance to run. The gushing of blood as the infected but around until it was done was so loud that I threw my phone away without a care in the world. Yet the only sound that reached me was the low, deep gurgle of blood and the throaty groan of the infected.
No amount of gory movies and books would have prepared me for that video and the silence that rang through the apartment after that prevailed for a very long time with the only noises being my gasps and puking. The clip went viral and everyone went crazy; traffic in the streets for miles as everyone tried to flee the city, flight tickets skyrocketed and the ruckus continued. I couldn't afford the tickets and I had nowhere else to go so I tried to order as much grocery as I could while trying to hold off the anxiety of living through yet another possible pandemic.
More clips started surfacing but I watched none of it, staying off the internet unless it was for work until finally hell couldn't be contained and the internet was shut down in the whole city. The government couldn't do shit for the virus yet so they ensured what they liked best – quiet. Work was close to impossible and salaries were further reduced regardless of the increasing bills.
In all the chaos of possibly a zombie apocalypse in construction and intense inflation, there was bound for things to go wrong — very, very wrong.
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Ripping off the fabric of a shirt from the backpack, I tied it around the long scratch on my arm. Darkness blurred my vision every time I exhaled and every inhale burned my lungs. Looking around, I realised I had run into the woods, which explained the itchy scratches everywhere on my body. But there was nowhere else to go and if I navigated in the right direction, I would arrive at the isolated military camp, which was a hopeful ray of my survival.
It wasn't supposed to happen; I was supposed to move south to downtown, where there could be a shit ton of infected but more chances of communication too. But the streets looked awfully empty as I walked and sprinted carefully. There were occasional abandoned cars that looked good as new but I did not dare peek in. Last thing I would want was an investigation after all the ruckus clears off, that too for petty theft. The cramp in my stomach was occasionally wrenching my insides but the adrenaline kept me going.
Humans are cute. Hold their hand, caress their scars and give them a warm seat and they'll think they are home. The empty roads, the quiet and the chilly breeze that brushed through my sweaty, filthy skin felt like a cold shower after enduring a heatwave. I got too comfortable so it was only right that I would get plowed to the street.
It was all in a split second. One second I was running and the next a heavy weight crashed to my side, effectively pushing me to the ground and scraping my exposed skin against the rough asphalt. But before I could cry out or even look at the force, there was a putrid stench scorching my nostrils and a growl above me.
There was a squelch of flesh being torn apart and a scream escaped my parched throat, a hoarse but disturbingly loud sound. I felt like I was floating just like I always imagined death to be except something was wrong. There was no pain. I wasn't pathetically thrashing in sheer agony of having my flesh bitten off and the infected person above me was not moving.
Lightheaded, I finally looked, really looked. Blood never looked so relieving. The makeshift spear on my hand was protruding through the neck of the infected and cold blood dripped down the puncture wound. The infected person, what looked like a young man, had his eyes stuck on me but they were vacant of any semblance of life. They were bloodshot and pupils dilated, looking like they would pop out of their sockets any moment. His body weight was crushing me and I couldn't breathe with my already throbbing head.
Pushing off the body, I rolled away, breathing in the open air. But before a complete breath, my body instinctively flipped and with wretched gags that shook my whole body, I puked again. At this point I wasn't sure what I was throwing up, probably my dying organs. The putrid stench was stronger and my gags worsened.
In the midst of that, I heard it this time. Shuffling, wheezing and groaning, footsteps. How did I forget my own scream? How was I not expecting it? My throat hurt and so did my entire body. I wanted to scream and cry with helplessness. But I knew I needed to move. I needed to get the fuck back up.
Because I might not be the main character in the whole story, but I was the main character in mine.
That's how I ended up running in a random direction, then more random directions doing anything to escape the footsteps. Every time I saw the slightest of shifts in my periphery, I changed directions. My makeshift spear remained digging into an infected person's throat and taking out any other knife would take time. I wanted to ram my head into a tree trunk for leaving behind the spear but I had to run then.
At one point, the road was deserted. The woods ran through one side and empty fields through another. There was no house around and nothing objectively obstructive of view. So I stopped but adrenaline was heavy so I stumbled to the ground and rolled on my back. Breathing. Just breathing.
The sky was clear but dusk was approaching. I didn't even want to think what would happen after nightfall so I kept breathing like it was a task. It was so silent that my head got louder again. I was hyper aware of my being, from my aching legs to my throbbing head and sinking heart. I couldn't close my eyes. Every time I gave in to the darkness, I saw a pair of bloodshot protruding eyes first, then a sensation – a cold liquid dripping down my arm and then finally, a knife lodged into a man's throat and the handle of that knife was held by-
I opened my eyes with as much life I had in me to the bright sky, unnerving quiet and my own heavy breathing. There was a nagging thought in my head that I wanted to throttle and bury but it came up again and again. To evade it, I sat up.
I took out a knife from my backpack, knowing that it wouldn't be half as useful as my spear but it was something better than nothing. I held it firmly but did not stand up. I couldn't. My legs were weak and hurt like a bitch. I had always contemplated how quickly things could go wrong but my estimation wasn't even close to what it was happening in reality. I remember basking in the warmth of my airy apartment and listening to music, laughing with my friends on call about how I was finally on the same land as BTS. But then suddenly it was chaos and now I had blood on my hands, filthy but it wasn't my own.
There was a cackling, a giggle around me and goosebumps lined my skin. I looked around for a moment when a realization hit me. It hit me so hard that I began sprinting again. Running towards the woods aimlessly, I ignored the burning of my soles and the scratches of small thin branches tearing my skin. All the while I kept thinking back to that sound.
It was me. I was laughing. I couldn't suppress the thought anymore. I was going insane.
--
Aimlessly wandering through the woods, I finally tried to breathe a little better. Stumbling through the huge trees and trying my best to navigate towards the setting sun, where a military camp should stand tall, I tried to ignore the burning pain that was spreading through my whole body.
The forest wasn't too thick. One couldn't see the other side at one glance but it wasn't complete wilderness. There were some rare trees marked by the government and some sections were fenced with wires. But all the big trees and growing tangled bines yet not one fruit caught my eye. No matter how much the infected scared me and no matter how much my whole body throbbed with a dull ache constantly, I couldn't ignore my cramped stomach and my dry mouth. But I couldn't drop my gait, not before nightfall.
The setting sun was like a halo in the distance and staring at it, as I moved forward, I felt a serenity take over me. There was nothing that was as hopeful as that constant ball of brightness in the desolate quiet of the woods, in a city filled with sick people.
So lost in the blinding light of the sun, I couldn't control my feet as they stepped on a dry branch on the ground and a loud creak echoed through the forest. The echoing felt like nature was mocking me, really laughing at me, pointing and saying, 'look at her, what a dumb bitch.'
Looking around me, I tried to confirm that nothing was going to jump on me at the next second. At least my back wouldn't be to the wall if something did pop up. At most, it would delay my navigation — or that's what I tried to assure myself. I was doing a fine job at it too, taking slow steps further towards the direction of the setting sun until I noticed it.
At some distance, there was a man walking towards my direction. He wasn't stumbling and that gave me hope that it could be another survivor. It couldn't be me all alone. But I didn't want to call out loud and attract attention. So I leaned against a thick tree, away from his sight, just the sound of his footsteps nearing me. The footsteps were steady, not haphazard. They felt conscious and they were closer than ever before.
I held my breath as I heard the footsteps just on the other side of the tree. I could see his shoes standing still. Peeking out a little more, I caught sight of him, looking straight ahead. His side profile looked completely untouched and with his completely fine posture, I was sure by then that he was indeed uninfected. A strange ray of joy sparked through me. He looked very alert and upright, probably because of the sound I made.
So I finally decided to step out from behind the bark. A step and then another until I was beside him. But he still didn't notice me, so I tried to reach out a hand and tap his shoulder. My shaking hands reached out and it was almost at his shoulder blade when I heard his breathing. He was breathing heavily which wasn't abnormal but it was followed by a deep gurgling sound – a growl.
In a beat I was ducking behind the tree again, only in time to catch his head turn in my direction; a knife was sticking out of his other eye, the sight making bile rise to my throat again as a scream threatened to erupt but at the distance he was in, one wrong move and I wouldn't be able to scream ever again. His other eye looked around keenly, heavy breathing and that same eerie gurgling groan as if he was choking on his own blood.
A few moments passed like that with me holding my breath, as he stood motionless. But after what felt like an eternity, he began walking again. Steady footsteps moving past the tree had me finally exhaling. But I couldn't waste any more time, it was already darkening. I had to get somewhere at least.
I took off in a sprint, the desire to put a distance between the infected and myself overwhelming my senses. Ducking below branches and jumping over roots, I let the air rage war on my skin as the surroundings changed to a blur. Even in all that overwhelming stimulation, I could feel it before I saw it. There was someone sprinting behind me. It was not a human. It had a protruding knife from its eye.
I wanted to scream out loud or at least cry in despair. But in lieu of all the mockery I made of characters in dystopian fictions at their obnoxious and unrealistic behaviour, even my mind was working on autopilot and instead of screaming or crying, I pushed my legs to run faster, letting the subdued animalistic urge of survival take over my senses, until I could see nothing but the peeking glimpses of the road at the distance.
My feet met the asphalt again and I let myself blink, feeling the water dripping down my cheeks. I couldn't perceive anything other than my own shoes hitting the road, slowing down with each fall to a jog then a walk and then a standstill.
I looked around the deserted road, panting. My vision was even more blurry than before but I couldn't miss the sight of a military barricade in the distance. This was the path to the military camp, where there should be people that can help me. The sun had dropped below the horizon but the bright halo remained and that too was slowly dimming.
I couldn't brush off the fact that there were probably infected around so I took quick strides to the path opposite the military barricade. A big white arrow was drawn on the road and it made me increase my pace. Soon enough a building came in my sight but it was still far and no matter how much I sped up, it felt far like a mirage.
"Help!"
I stumbled to a stop. There was a looming fear that I was going insane but I was sure I heard someone scream for help. It was coming from the darkening forest. My heart thudded loudly in my chest as I stared at the darkness.
"Help me please!"
I heard it distinct this time and closer than before. There was indeed another person. But I couldn't forget the infected person I encountered before. With the loud shouting from this person asking for help, he would definitely be following the source too. There was a person asking for help and there was an infected person probably tailing the sound.
I've never counted myself as a great person and that wasn't due to humility. I was never a great person. I always prioritized myself first and when the situation had come to a literal man-eating-man situation, I saw nothing wrong in it.
So I sprinted towards the building, ignoring the calls for help, the sound ringing in my ears like a siren.
"Help!"
"Help, please, someone!"
"HELP!"
--
It wasn't a military camp. It didn't look like one at least. It was a huge building, fenced with a huge metal gate, but empty. Deserted. Not one person was around. But I didn't want to lose hope, they could have locked themselves in somewhere.
The gate was open thankfully, so I tried to push myself in through that but ended up opening it slightly wider than before albeit soundlessly. It was dark, the halo of the sun gone. The sky was just minutes away from darkening to a void.
With quiet footsteps I walked towards the only door in sight. It was huge but opened even with a gentle push, no creaking. The place was quiet. With the staircases and the multiple hallways, it looked like the barracks. But no lights were on and nothing was in sight. There was a chill running down my spine as I slowly stepped towards the first hallway to the left.
The long, narrow passage gave way to another big door. The door was closed but through the big glasses on the door, I could well see the inside. I could barely conceal my cry when I saw numerous infected people stumbling around in what looked like the cafeteria. There was food spilled on the ground and they all looked like chefs but a few were wearing military boots too.
My last hope drowned. I could only visualise letting an infected person tear into me. The pain would be immense but it won't last too long. Muffled sobs uncontrollably poured out of me as I stared at the people inside walking around like monsters of the night, waiting for one little sound, then they would tear them down to dust.
I was subconsciously staring at the young soldier who had a huge chunk of his forearm missing. He was young, might have even enlisted recently. His buzz cut looked newly shaped. It made my heart lurch in agony. I couldn't falter the ringing of my ears, the only sound enthralling my eardrums was the cry for help that I ignored. When I closed my eyes to blink I saw a man with a knife sticking out of his throat, a knife that I stabbed him with. It was so terrifying that I wanted to never close my eyes again.
The young soldier's eyes met mine all of a sudden and I took a step back. His eyes remained on mine when I moved further and further back until I began sprinting in the opposite direction. The adrenaline got the best of me and forsaking the sense of directions, I ran up the staircase. The sound of my shoes hitting the floor hurt my own ears. I had no idea where I was running to but I couldn't stop.
Not until I was suddenly pulled back inside a room and thrown against the wall with a heavy body up against me and a hand on my mouth interrupting the scream that I was about to let out. It was dark but I could make out a tall silhouette gently closing the door with one hand while still holding me against the wall.
Tears flowed out my eyes as I heard a familiar groaning right outside the door. Squeezing my eyes shut, I pressed myself to the wall as if it would just suck me in and free me from the wall but the stranger looked unshaken, his hand remained firm on my mouth and eyes on the door. A moment or two passed like that with me holding my breath and a loud drumming of heartbeat in my ears before abnormal footsteps slowly moved past the door and somewhere further down the hall.
The stranger still showed no intent of moving and there were hundreds of thoughts running through me but I let him wait for another minute or so before he moved and let me collapse to the floor like a heap of messy laundry. I couldn't control my trembling body, letting everything over the past weeks finally take their toll on me. I couldn't even look up and catch the stranger step back until he was on the opposite wall where he slid down to the floor too.
"Are you hurt somewhere?"
There was a gentle familiarity in his voice that made my stomach clench uncomfortably. I had no idea how much time had passed since I stopped crying.
"Just some scratches."
He suddenly looked alert and stood up. It took me a few seconds to comprehend his reaction so I was quick to clear the misunderstanding, "Not by the infected people. Just tree branches. I ran through the woods."
There was a sigh heard in the room and I watched his silhouette move to the small window with the blinds down. His shoulders were broad and his physique looked intimidating from my position on the ground but it strangely did not throw me off. There was something about him that felt unnaturally familiar. I didn't know how.
He parted the blinds and let more light flood in before turning to face me. I blinked at him for a moment, my head couldn't process what was going on. The familiar kind eyes, the high nose bridge and the pouty lips were all features of one person I recognised like the back of my hand; someone I had spent years fangirling over. I couldn't mistake that countenance, never. But the only sigh of misery that left me was the consequences I was seeing him in.
I wasn't ready to meet Kim Seokjin in the middle of an apocalypse.
There was utter silence in the room, only our breathing and probably my drumming heart. He had returned to his seat at the opposite wall while I remained fixated to my side. I had so many questions, so many things to say but moving my lips felt like a task. I had nothing on me that would get me going now that the adrenaline had run out. So we remained in an exhausting silence.
"Is the road clear?" he whispered.
"Barely. The woods are not clear so I doubt the road will stay safe too long."
He didn't reply and I couldn't resist the urge so I asked him, "How are you here?"
"I was supposed to be discharged the next day when all this happened. I was in my room packing up when I heard some commotion downstairs."
I didn't need to know what commotions nor did he feel it to be said. Silence prevailed when I couldn't come up with a reply but there was something shifting in me. I was breathing a little easier.
"I'm not going to be here anymore though."
I watched him stand up and move to the bed in the corner and there was a slightly coarse sound of a wrapper being torn, of a small protein bar when it was brought before my eyes. I looked up at Jin who held the bar in front of me, another small water bottle with some water in it.
I was confused. Why was he showing it to me? Was he giving it to me? He couldn't be that stupid. Who would share food and water in this scarcity? I kept staring at the protein bar letting my mouth water and my stomach groan loudly. But I didn't take it from his hand.
It must have been frustrating for him because he suddenly dropped to the floor right in front of me and shoved the bar in my hand and placed the water bottle before me. When my limp hand finally fisted around the bar, he brought my hand to my mouth and shoved it in.
I could have cried as the taste of the melting bar sent a few shudders to my body and I was gobbling it up in less than a few seconds.
"I'm sorry I'm usually more gentle. But I can't be patient right now."
Mouth full with the last bite of the bar, I reached for the water bottle watching him with keen eyes as he continued, "I can only give you this much. I'll leave tomorrow."
The water flowing down my burning throat sent another round of shudders down my body and my eyes closed in bliss. I saved a few sips for later and let the embarrassing sound of my stomach groaning be heard before I processed his words.
"To where? It's hell out there."
"My brothers. They are in the main camp."
I didn't agree with him wholeheartedly but I understood him. The moment my brain registered that it was Kim Seokjin, my mind went to the other six members. The exhaustion had gotten overwhelming and the thought had left me. Hearing it from him was a different feeling. He was the eldest, his sense of responsibility had to be peaking.
I had no idea when I fell asleep but when I woke up it was day again. Lights poured in through the windows with the blinds pushed up. A rustle of fabric made me jump up to a stand still when I remembered I wasn't alone.
Jin was walking around the room, randomly checking drawers and tables. I felt my thoughts to be more organised than last night so I could finally process a lot of things; first being the fact that I wasn't dead or infected yet and I somehow met Kim Seokjin and the second, he is ethereal.
He looked like an angel with the sun beaming on his face, as he looked out. What were the odds of me ending up with him of all people? But before I could further contemplate the odds, he turned to me with a small grimace for a smile but I swooned nonetheless.
"Slept well? You should keep your guards up now. I'll get going."
It all came back to me in an instant. He did talk about leaving to look for the other members and I didn't remember what I replied back.
"Have you been outside? It's hell."
"I know, you've told me before."
"How do you plan to make it there?"
He looked at me with his backpack in hand, "I'm not sure. I don't have much with me, just some scraps for snacks and a bottle of water or two."
I couldn't help the quake of my body when I recalled the infected people I had encountered on my way. At least I had a knife, it looked like he was charging in without anything.
I noticed my own backpack lying abandoned so I picked it up and took out one of the knives from in there.
"There you go," I held it out to him as he continued staring with an unreadable expression, "you will need some kind of protection. I suppose you happen to not have a gun, right?"
He stared at the knife for a moment and I was about to take it back, afraid of his widening eyes but instead he suddenly spoke up, "Guns! There are guns here somewhere-"
"In this room?"
"No, maybe in the gym."
I had no idea what to do with this piece of information so I waited for his mind to continue turning the gears.
"I'm going to try and look for one before I leave."
He didn't wait for any affirmation from my side, immediately moving towards the door when an uncomfortable feeling began sinking in my stomach. He was really leaving like that. Hand on the doorknob, he was about to pull it open when I was pulling his arm back.
Wide eyed he stared as if I had grown two heads, "what are you doing?"
"I'll go with you."
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didanawisgi · 5 months
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Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and COVID-19 infection has led to worsened outcomes for patients with cancer. SARS-CoV-2 spike protein mediates host cell infection and cell-cell fusion that causes stabilization of tumor suppressor p53 protein. In-silico analysis previously suggested that SARS-CoV-2 spike interacts with p53 directly but this putative interaction has not been demonstrated in cells. We examined the interaction between SARS-CoV-2 spike, p53 and MDM2 (E3 ligase, which mediates p53 degradation) in cancer cells using an immunoprecipitation assay. We observed that SARS-CoV-2 spike protein interrupts p53-MDM2 protein interaction but did not detect SARS-CoV-2 spike bound with p53 protein in the cancer cells. We further observed that SARS-CoV-2 spike suppresses p53 transcriptional activity in cancer cells including after nutlin exposure of wild-type p53-, spike S2-expressing tumor cells and inhibits chemotherapy-induced p53 gene activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2. The suppressive effect of SARS-CoV-2 spike on p53-dependent gene activation provides a potential molecular mechanism by which SARS-CoV-2 infection may impact tumorigenesis, tumor progression and chemotherapy sensitivity. In fact, cisplatin-treated tumor cells expressing spike S2 were found to have increased cell viability as compared to control cells. Further observations on gamma-H2AX expression in spike S2-expressing cells treated with cisplatin may indicate altered DNA damage sensing in the DNA damage response pathway. The preliminary observations reported here warrant further studies to unravel the impact of SARS-CoV-2 and its various encoded proteins including spike on pathways of tumorigenesis and response to cancer therapeutics.
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gatheringbones · 1 year
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[“The idea that work can be morally injurious has not gone entirely unnoticed. At the height of the coronavirus pandemic, it was described in often-moving detail in articles about physicians and nurses who were forced to make excruciating decisions—which patients should be hooked up to ventilators? who should be kept alive?—as hospitals were inundated with COVID-19 cases. “None of us will ever be the same,” wrote an ER doctor in New York City who worked on the front lines of the pandemic and published a firsthand account of the anguish that she and her colleagues felt.
Notably, though, it took an unforeseen crisis to thrust doctors into such a role, a crisis that eventually abated. In the case of many dirty workers, the wrenching choices—and the anguish they can cause—occur on a daily basis because of how society is organized and what their jobs entail. Unlike doctors, moreover, these workers are not lionized by their fellow citizens for working in a profession that is widely viewed as noble. To the contrary, they are stigmatized and shamed for doing low-status jobs of last resort.
People who are willing to do morally suspect things simply to earn a paycheck deserve to be shamed, some may contend. This is how many advocates of migrant rights feel about the Border Patrol agents who have enforced America’s inhumane immigration policies in recent years. It is why some peace activists have accused drone operators involved in targeted killings of having blood on their hands. These activists have a point.
The dirty workers whose stories unfold in the pages that follow are not the primary victims of the systems in which they serve. To the people on the receiving end of their actions, they are not victims at all. They are perpetrators, carrying out functions that often cause immense suffering and harm. But pinning the blame for dirty work solely on the people tasked with carrying it out can be a useful way to obscure the power dynamics and the layers of complicity that perpetuate their conduct. It can also deflect attention from the structural disadvantages that shape who ends up doing this work. Although there is no shortage of it to go around, the dirty work in America is not randomly distributed. As we shall see, it falls disproportionately to people with fewer choices and opportunities—high school graduates from depressed rural areas, undocumented immigrants, women, and people of color. Like jobs that pay poorly and are physically dangerous, such work is chiefly reserved for less privileged people who lack the skills and credentials, and the social mobility and power, that wealthier, more educated citizens possess.”]
eyal press, from dirty work: essential labor and the hidden toll of inequality in america, 2021
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sataniccapitalist · 9 months
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#thewaronyou
Another winter of death is now unfolding in the United States and across the Northern Hemisphere as the JN.1 variant of the coronavirus continues to surge globally. Wastewater data from the United States released Tuesday indicate that upwards of 2 million people are now being infected with COVID-19 each day, amid the second-biggest wave of mass infection since the pandemic began, eclipsed only by the initial wave of the Omicron variant during the winter of 2021-22.
There are now reports on social media of hospitals being slammed with COVID patients across the US, Canada and Europe. At a growing number of hospitals, waiting rooms are overflowing, emergency rooms and ICUs are at or near capacity, and ambulances are being turned away or forced to wait for hours to drop off their patients.
According to official figures, COVID-19 hospitalizations in Charlotte, North Carolina are now at their highest levels of the entire pandemic. In Toronto, Dr. Michael Howlett, president of the Canadian Association of Emergency Physicians, told City News, “I’ve worked in emergency departments since 1987, and it’s by far the worst it’s ever been. It’s not even close.” He added, “We’ve got people dying in waiting rooms because we don’t have a place to put them. People being resuscitated on an ambulance stretcher or a floor.”
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Dr. Joseph Khabbaza, a pulmonary and critical care specialist at the Cleveland Clinic, told the Today Show website: “The current strain right now seems to be packing a meaner punch than the prior strains. Some features of the current circulating strain probably (make it) a little bit more virulent and pathogenic, making people sicker than prior (variants).”
Indeed, two recent studies indicate that JN.1 more efficiently infects cells in the lower lung, a trait that existed in pre-Omicron strains which were considered more deadly. One study from researchers in Germany and France noted that BA.2.86, the variant nicknamed “Pirola” from which JN.1 evolved, “has regained a trait characteristic of early SARS-CoV-2 lineages: robust lung cell entry. The variant might constitute an elevated health threat as compared to previous Omicron sublineages.”https://www.youtube-nocookie.com/embed/1MGIQxPf0Ig?rel=0An appeal from David North: Donate to the WSWS todayWatch the video message from WSWS International Editorial Board Chairman David North.DONATE TODAY
The toll on human life from the ongoing wave of mass infection is enormous. It is estimated that one-third of the American population, or over 100 million human beings, will contract COVID-19 during just the current wave. This will likely result in tens of thousands of deaths, many of which will not be properly logged due to the dismantling of COVID-19 testing and data reporting systems in the US. When The Economist last updated its tracker of excess deaths on November 18—before the JN.1 wave began—the cumulative death toll stood at 27.4 million, and nearly 5,000 people were continuing to die each day worldwide.
The current wave will also induce further mass suffering from Long COVID, which has been well known since 2020 to cause a multitude of lingering and often debilitating effects. Just last week, a pre-print study was published in Nature Portfolio showing that COVID-19 infection can cause brain damage akin to aging 20 years. The consequences are mental deficits that induce depression, reduced ability to handle intense emotions, lowered attention span, and impaired ability to retain information.
Other research indicates that the virus can attack the heart, the immune system, digestion and essentially every other critical bodily function. The initial symptoms of COVID-19 might resemble those of the flu, but the reality is that the virus can affect nearly every organ in the body and can do so for years after the initial infection. While vaccination slightly reduces the risks of Long COVID, the full impact of the virus will be felt for generations.
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The latest winter wave of infections and hospitalizations takes place just eight months after the World Health Organization (WHO) and the Biden administration ended their COVID-19 public health emergency (PHE) declarations without any scientific justification. This initiated the wholesale scrapping of all official response to the pandemic, giving the virus free rein to infect the entire global population ad infinitum.
A virtual blackout of any mention of the coronavirus in the corporate media accompanied the swan song of official reporting. From then on, if illnesses at hospitals or among public figures were referenced at all, it was always with the euphemism “respiratory illness.” The words COVID, coronavirus and pandemic have been all but blacklisted, and the facts about the dangers of the disease have been actively suppressed.
Summarizing the cumulative results of this global assault on public health, the WSWS International Editorial Board wrote in its New Year 2024 statement:
All facts and data surrounding the present state of the pandemic are concealed from the global population, which has instead been subjected to unending lies, gaslighting and propaganda, now shrouded in a veil of silence. There is a systematic cover-up of the real gravity of the crisis, enforced by the government, the corporations, the media and the trade union bureaucracies. Official policy has devolved into simply ignoring, denying and falsifying the reality of the pandemic, no matter what the consequences, as millions are sickened and thousands die globally every day.
In response to the latest wastewater data, there have only been a handful of news articles, most of which have sought to downplay the severity of the current wave and largely ignored the deepening crisis in hospitals.
The official blackout has given rise to an extraordinary contradiction in social life. The reality of mass infection means that everyone knows a friend, neighbor, family member or coworker who is currently or was recently sick, or even hospitalized or killed, by COVID-19. Yet the unrelenting pressure to dismiss the danger of the pandemic means that shopping centers, supermarkets, workplaces and even doctor’s offices and hospitals are full of people not taking the basic and simple precaution of masking to protect themselves. Every visit outside one’s home carries the risk of being infected, with unknown long-term consequences.
As the pandemic enters its fifth year, it is critical to draw the lessons of this world historical experience. The past four years have demonstrated unequivocally that capitalist governments are both unwilling and incapable of fighting this disease. Their primary concern has always been to ensure the unabated accumulation of profits by corporations, no matter the cost in human lives and health.
The real solution to the coronavirus is not to ignore it, but to develop a campaign of elimination and eradication of the virus worldwide. To do so requires the implementation of mask mandates, mass testing and contact tracing, as well as the installation of updated ventilation systems and the safe deployment of Far-UVC technology to halt the spread of the virus. The resources for this global public health program must be expropriated from the banks and financial institutions, which are responsible for the mass suffering wrought by the pandemic.
All of these measures cut directly across the profit motive and the real disease of society: capitalism. As such, the struggle against the coronavirus is not primarily medical or scientific, but political and social. The international working class must be educated on the real dangers of the pandemic and mobilized to simultaneously stop the spread of the disease and put an end to the underlying social order that propagates mass death. This must be developed as a revolutionary struggle to establish world socialism.
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covid-safer-hotties · 22 days
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Global Emergency Compounded by the AIDS-like Features of SARS-CoV-2 Infection - Published Sept 1, 2024
Over a million people in the US are being infected with severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) every day.
Originally named after the acute respiratory syndrome it can cause as a consequence of blood vessel damage in the lungs, SARS-CoV-2 is actually primarily a blood vessel virus that spreads through the airways. It causes a complex multisystem disease (1). It is airborne (2). It can persist in the body, and is detectable in body and brain tissue even at autopsy of “recovered” patients (3).
Each infection ages the body, causes damage to the blood vessels and the immune system, and affects organs including the heart, lungs, liver, kidneys, bones, etc. (4, 5, 6)
Each infection ages the brain. Specifically, it reduces gray matter and cognitive ability (7), and potentially IQ score (8). It increases the risk of psychiatric disorders (9). SARS-CoV-2 has also been identified as contributing to accelerated dementia (10).
The potential post-acute phase impacts of SARS-CoV-2 include long COVID, some manifestations of which are chronic conditions that can last a lifetime, including heart disease, diabetes, myalgic encephalomyelitis and dysautonomia (11).
The Economist has estimated excess deaths from the beginning of the Pandemic through May 2024 at up to 35 million people worldwide. (12)
In Addition, Many Scientists Are Now Issuing Warnings… SARS-CoV-2 triggers a new airborne form of Acquired Immune Deficiency Syndrome (13, 14, 15) (some are proposing specific terms such as “CoV-AIDS”).
This is not AIDS as we know it from human immunodeficiency virus (HIV) infection, it is a new type of acquired immunodeficiency syndrome with different deleterious effects on immune function (16, 17, 18, 19, 20, 21), but both resulting in increased vulnerability to infections (22). Immune system deficiency and other COVID properties also suggest a potential link to greater risk of cancers (23, 24, 25, 26, 27).
The “original” AIDS caused by HIV takes up to around 10 to 15 years to make its presence felt, with the initial infection usually barely noticed and often resembling the common cold or a flu-like disease until its damage manifests itself leading to death in the absence of treatments (28, 29).
With SARS-CoV-2, immunodeficiency develops in the weeks and months following infection. It involves reduction and functional exhaustion of T Cells (30), enhanced inhibition of MHC-I expression (31), downregulating CD19 expression in B cells (32) and other evidence of immune dysregulation (33, 34). In one study, the dysregulation persisted for 8 months following initial mild-to-moderate SARS-CoV-2 infection, the length of the study (35). There is no “cure” for any of the damage caused by SARS-CoV-2 including immune dysregulation.
Did You Know? Repeated infections are leading to prolonged immune dysregulation, and increase the risk of progressive disability and death.
Long COVID is a multisystem disease with debilitating symptoms, which has had a profound impact on society and the global economy. In the USA, economists have estimated that long COVID will incur cumulative future costs of more than US$4 trillion (36, 37).
The worldwide devastating economic consequences of this mass disabling event have been measured in terms of total work hours and GDP lost around the world (38).
It theoretically only takes a single viral particle to initiate an infection, and most infections are initiated by very few viral particles (39).
Despite current popular belief, the immune system is NOT a muscle, and does NOT benefit from being repeatedly challenged with disease-causing microbes. In fact, its finite resources are depleted with each new infection.
Herd immunity is unattainable for a rapidly mutating, immune-disrupting virus, and there is no basis to believe that a vascular infection will evolve into the common cold. Continuing to ignore SARS-CoV-2 will not make it go away. Depriving the virus of publicity does not deprive it of its continuing lethal effects.
SARS-CoV-2 is continuing to evolve and mutate – it is not running out of evolutionary space. It is not a cold or the flu, but primarily a blood vessel disease. It is damaging society as we know it.
How many repeated infections can we expect young people to endure and survive? Even if they get only 1 infection each year, that’s 10 infections in 10 school years. This is not compatible with health and a long life. Repeated infections can lead to long COVID and shortened lifespans.
How Do We Protect Ourselves, How Do We Protect Our Children, When Government Public Health Advice Has Failed?
By reducing transmission so that R0 remains less than one (meaning that each person infects less than one other), we can suppress and gradually eliminate the virus, targeting a safer return to pre-2020 normal.
Handwashing is helpful, but it is not the main way to stop the spread of this airborne virus.
Respirators can block 95% or more of virus particles through electrostatic action, and are therefore highly effective at reducing infection even if only one person in a conversation is wearing them. They are far more effective if all people are wearing them (40).
Transmission can be reduced with HEPA filtration and ventilation of indoor air.
The virus spreads more quickly in indoor settings, but also spreads outdoors.
For medical facilities, it is essential to clean the air with ventilation and filtration and require universal high-quality masking (with N-95/ FFP3 respirators or better) to protect medical staff and patients.
For workplaces, clean air will reduce transmission; and encouraging employees to test and stay home when infectious is essential. High-quality masking should be encouraged in the case of symptoms, a sick person at home, or any other suspicion that one could be carrying the virus. Remote work should be normalized and encouraged wherever possible.
For entertainment venues, events should be held outdoors when possible; and if indoors, clean air is key to protecting audiences. Audiences should also be encouraged to wear respirators to avoid getting infected and infecting others. Digital streaming options should always be offered.
For restaurants, an emphasis on outdoor dining will substantially reduce transmission. Patio service should be encouraged, and indoor dining areas should be well-ventilated with a high level of air-exchanges. Home or curbside delivery offers a safer alternative.
For schools, clean air will reduce transmission; encouraging students to test and stay home when infectious is essential to preserving their health. Masking or remote learning should be initiated whenever a case is detected or the incidence in the general population sharply increases. A permanent hybrid model / digital option can accommodate children with disabilities or those who simply do better learning from home.
Teachers and medical professionals may prefer to use transparent masks, or to wear HEPA-filtered headgear equipment that may be more universally tolerated/accepted.
To track our progress, we need sustained wastewater and population-level testing.
With just 60-70 percent of people taking mitigation measures such as masking, testing and isolating when infected, we can dramatically reduce forward transmission of the virus.
Even with very imperfect measures, as long as one infected person does not infect more than one person on average, the virus will eventually die out. The fewer people each person infects on average, the faster it will happen.
We still have a window of opportunity. Protecting ourselves and our families is in fact protecting the economy and the continued orderly functioning of our society.
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learnwithmearticles · 3 months
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GUV
Can GUV revolutionize the world of public health?
Germicidal ultraviolet (GUV) is a range of light wavelengths capable of killing pathogens. Recent research indicates that implementing GUV in public spaces could reduce the transmission of respiratory viruses by 30% to 75% - a wide range but, overall, effective, especially with the many potential benefits.
Benefits
As ultraviolet light, GUV works through radiation; therefore, it is unintrusive and passive.
At the height of the COVID-19 pandemic, a significant portion of adults in the U.S.A. did not wear masks to reduce the spread of the virus. This resulted in many deaths and an acceleration of the virus’s mutation process. GUV does not require any action from the individual, reducing the harmful effects of disinformation and ignorance.
The COVID-19 pandemic also endured a period of rationing personal protective equipment (PPE), which increased health risks to medical personnel and patients around the world. Researchers have found GUV to be effective in killing the coronavirus and making PPE resusable.
GUV can also be used in addition to PPE to increase the sterility of medical rooms. In a study of a burn intensive care unit, GUV implementation led to an 89% decrease in airborne bacteria and a 69% decrease in surface-borne bacteria.
GUV targets a wide range of pathogens, both bacterial and viral, such as the multiple iterations of coronaviruses. Through mutation, many bacteria become drug resistant. By damaging nucleic acids, cellular building blocks, GUV is effective on even drug-resistant pathogens.
The ‘passive action’ of GUV makes it ideal for handling pandemics. While other interventions require development time, societal response, and ongoing maintenance when a new pathogen is identified, GUV can continually work in the background without continued interference.
This comes on the condition, of course, that we figure out a healthy way to use GUV.
Types of GUV
Because ultraviolet light can also have negative health effects, different forms of GUV are being studied for effectiveness and potential harm. The primary three investigated are full-room systems, upper-room systems, and in-duct systems.
Full-room GUV 
A straightforward name, full-room GUV has UV-C lights on a ceiling or wall irradiating an entire room. When the room is unoccupied, this is an easy way to make the room safer from pathogens. This study gives the example of a surgery room after the surgeons and patient have left.
This variety does not work when the room is occupied. Continuous exposure to UV-C lights is harmful to the skin and eyes, making full-room GUV limited in its potential use.
Within this variety, far-UVC light might be the solution. The wavelength of far-UVC light can deactivate bacteria and viruses but cannot pass far enough into skin and eyes to cause damage.
Upper-room GUV
Upper-room GUV is also a complicated option. It sticks to the upper sections of a room, and thus doesn’t expose human skin to UV light. This also means it is less effective, because it isn’t targeting the areas of the room where transmission occurs.
Perhaps with additional airflow that directs airborne pathogens upwards, this method could be more effective.
In-duct GUV
Due to its removal from main occupied areas, in-duct GUV permits the use of stronger UV wavelengths against pathogens. This variety also requires good airflow and is even farther from transmission areas. It is considered inferior to the above two varieties. 
Researchers are continuing to investigate the most effective and safe forms of GUV. Being able to widely implement this anti-bacterial and anti-viral strategy could immensely benefit public health and decrease the spread of an abundance of ailments. It could be useful in many ways in hospitals, doctors’ offices, and many public spaces as an unobtrusive aid.
Additional Resources
1. GUV in  Medical Centers 
2. GUV for a Pandemic
3. Founders Pledge Study
4. GUV on PPE
5. GUV Overview
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