#US Acute Myeloid Leukemia Market size

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The Transformative Growth of the US Acute Myeloid Leukemia Market

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What is the Size of US Acute Myeloid Leukemia Industry?

US Acute Myeloid Leukemia Market is expected to grow at a CAGR of ~ % in 2022 and is expected to reach ~USD Mn by 2028. The US Acute Myeloid Leukemia market is the rapid advancement in precision medicine and targeted therapies. The emergence of innovative treatments tailored to the genetic and molecular characteristics of individual AML patients has transformed the treatment landscape. Targeted therapies, such as FLT3 and IDH inhibitors, capitalize on specific genetic mutations driving AML, resulting in higher response rates and improved outcomes compared to traditional approaches.

Precision medicine's ability to identify the most effective treatment for each patient not only enhances therapeutic efficacy but also reduces unnecessary treatments, mitigating side effects and improving overall quality of life. This paradigm shift is bolstered by technological progress in molecular profiling techniques like next-generation sequencing, allowing for accurate genetic profiling and treatment customization.

Furthermore, regulatory support and accelerated approval pathways for targeted therapies have expedited their availability to patients. Pharmaceutical companies' increasing investment in research and development of novel agents, along with collaborations between academia and industry, leads to grow this market even more.

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US Acute Myeloid Leukemia Market by treatment type

The market is segmented by Treatment type into Chemotherapy, Targeted Therapy, Hormone Therapy, Immunotherapy and Others. Targeted Therapy is the dominant segment in the US Acute Myeloid Leukemia market in 2022. Specialty Centers, dedicated to the diagnosis, treatment, and management of specific medical conditions like AML, offer a concentrated and specialized approach to patient care. Their dominance in the AML market is driven by their unique capabilities to provide comprehensive and tailored treatments that address the complex needs of AML patients.

US Acute Myeloid Leukemia Market by end -user industry

The market is segmented by End-User into Hospitals, Homecare, Specialty Centers, Pharmacies and Others. Among these, Specialty Centers are the dominant End-User in the US Acute Myeloid Leukemia market in 2022. Specialty centers have a higher level of expertise and experience in treating specific types of cancer, including acute leukemia. They typically have specialized medical professionals, including hematologists and oncologists, who are well-versed in the latest treatment protocols and research. These centers are equipped with state-of-the-art diagnostic and treatment facilities that are specifically tailored to the needs of leukemia patients. This can include advanced imaging technologies, specialized laboratories, and access to cutting-edge therapies.

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US Acute Myeloid Leukemia companies market by Region

The US Acute Myeloid Leukemia market is segmented by Region into North, South, East, West. The dominance region is North in the US Acute Myeloid Leukemia Market in 2022. the North region often benefits from a higher level of funding for medical research, including AML. Federal funding agencies, private foundations, and pharmaceutical companies frequently channel resources into institutions within this region, allowing for greater research capabilities and clinical trials infrastructure.

Competition Scenario in US Acute Myeloid Leukemia Market

The US acute myeloid leukemia market was characterized by the presence of several prominent pharmaceutical companies and biotechnology firms striving to establish their presence and gain a competitive edge.

Larger corporations, smaller biotechnology companies making significant contributions to the AML landscape. Companies like Agios Pharmaceuticals and Daiichi Sankyo were gaining attention for their novel therapies targeting AML-associated mutations. These players are often at the forefront of introducing precision medicine approaches to AML treatment, taking advantage of advancements in genetic profiling and molecular diagnostics.

The competition is further intensified by research collaborations and partnerships between pharmaceutical companies, academic institutions, and research organizations. These collaborations aimed to combine resources, expertise, and insights to accelerate the development of effective therapies.

What is the Expected Future Outlook for the Overall US Acute Myeloid Leukemia market?

The US Acute Myeloid Leukemia market was valued at USD ~Million in 2022 and is anticipated to reach USD ~ Million by the end of 2028, witnessing a CAGR of ~% during the forecast period 2022- 2028. Pharmaceutical companies have been actively researching and developing novel therapies for Acute Myeloid Leukemia, with a focus on improving patient outcomes and reducing the side effects associated with traditional treatments like chemotherapy.  The approval of new drugs, such as FLT3 and IDH inhibitors, has offered fresh therapeutic avenues for specific subsets of Acute Myeloid Leukemia patients with genetic mutations.

The future outlook for the US Acute Myeloid Leukemia market is anticipated to be influenced by a combination of factors including advancements in treatment options, evolving regulatory landscapes, and a growing understanding of the molecular basis of Acute Myeloid Leukemia. The market has been witnessing a shift towards personalized medicine, with increasing emphasis on targeted therapies and precision medicine approaches.

Furthermore, the integration of innovative technologies like next-generation sequencing (NGS) has enhanced our understanding of Acute Myeloid Leukemia’s molecular complexities, allowing for better patient stratification and treatment selection. This trend toward molecular profiling and personalized treatment regimens is likely to continue shaping the market landscape.

However, challenges persist. Despite progress, Acute Myeloid Leukemia remains a difficult-to-treat disease with a high relapse rate. Overcoming drug resistance and developing effective strategies for patients who do not respond well to existing therapies remain critical areas of focus.

Additionally, the cost of novel therapies and access to these treatments could also impact their adoption and availability. The regulatory environment, including expedited pathways for drug approvals, continue to influence market dynamics.

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Advances in Leukemia Therapeutics: Innovations and Emerging Trends

The Evolving Landscape of Leukemia Treatment

Leukemia, a group of malignancies that affect the blood and bone marrow, continues to challenge the medical community with its complexity and variability. Recent years have seen significant strides in leukemia therapeutics, driven by advancements in drug development, personalized medicine, and novel therapeutic strategies. These innovations are transforming treatment paradigms, offering new hope to patients and paving the way for more effective and targeted therapies.

Breakthroughs in Drug Development

One of the most significant advancements in leukemia therapeutics is the development of targeted therapies. Unlike traditional chemotherapy, which indiscriminately kills rapidly dividing cells, targeted therapies are designed to attack specific molecules involved in cancer progression. For instance, tyrosine kinase inhibitors (TKIs) like imatinib, dasatinib, and nilotinib have revolutionized the treatment of chronic myeloid leukemia (CML). These drugs target the BCR-ABL protein, a key driver of CML, leading to improved outcomes and reduced side effects compared to conventional treatments.

In addition to TKIs, the approval of novel agents such as venetoclax has marked a significant leap forward. Venetoclax targets the BCL-2 protein, which is often overexpressed in leukemia cells, thereby promoting their survival. By inhibiting BCL-2, venetoclax enhances the effectiveness of chemotherapy and has shown promise in treating acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL).

Advances in Immunotherapy

Immunotherapy is another area where substantial progress has been made. Chimeric antigen receptor (CAR) T-cell therapy represents a groundbreaking approach, especially for acute lymphoblastic leukemia (ALL) and some cases of CLL. This therapy involves modifying a patient's T-cells to express a CAR that targets leukemia-specific antigens. The modified T-cells are then reintroduced into the patient’s body, where they identify and destroy leukemia cells.

Recent studies have demonstrated the efficacy of CAR T-cell therapies, leading to impressive remission rates in patients with refractory or relapsed leukemia. However, this approach is not without challenges. The risk of cytokine release syndrome (CRS) and neurotoxicity remains a concern, and ongoing research aims to enhance the safety and effectiveness of CAR T-cell therapies.

The Leukemia Therapeutics Market size was USD 16 Billion in 2023 and is expected to Reach USD 27.28 Billion by 2031 and grow at a CAGR of 6.9% over the forecast period of 2024-2031.

Precision Medicine and Genetic Insights

The era of precision medicine has ushered in a new approach to leukemia treatment, with a focus on tailoring therapies based on individual genetic profiles. Advances in genomic sequencing have identified specific mutations and genetic alterations associated with different types of leukemia. For example, mutations in the FLT3 gene are common in AML, and targeted inhibitors like midostaurin are being used to address these mutations.

Similarly, research into the genetic underpinnings of CLL has led to the development of drugs that target specific mutations or pathways involved in the disease. By understanding the unique genetic landscape of each patient’s leukemia, clinicians can select the most effective therapies and potentially improve treatment outcomes.

Future Directions and Challenges

While the progress in leukemia therapeutics is promising, several challenges remain. The high cost of novel therapies, including CAR T-cell treatments, poses a significant barrier to access for many patients. Additionally, the development of resistance to targeted therapies and immunotherapies requires ongoing research to develop new and effective treatment options.

Looking ahead, researchers are exploring combination therapies, novel drug targets, and personalized approaches to overcome these challenges. The integration of artificial intelligence and machine learning in drug discovery and treatment planning holds the potential to further accelerate progress in leukemia therapeutics.

Conclusion

The field of leukemia therapeutics is undergoing a transformative phase, with innovations in drug development, immunotherapy, and precision medicine leading the way. These advancements are not only enhancing treatment outcomes but also offering new hope to patients. As research continues to evolve, the focus will remain on overcoming current challenges and pushing the boundaries of what is possible in the fight against leukemia.

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Leukemia Therapeutics Market Size: Competitive Landscape Analysis

The Leukemia Therapeutics Market size was USD 16 Billion in 2023 and is expected to Reach USD 27.28 Billion by 2031 and grow at a CAGR of 6.9% over the forecast period of 2024-2031.The leukemia therapeutics market is experiencing rapid growth, driven by advancements in targeted therapies and personalized medicine. With an increasing understanding of the genetic and molecular mechanisms underlying various leukemia subtypes, pharmaceutical companies are developing innovative treatments that offer improved efficacy and reduced side effects. The market is also benefiting from a surge in research and development activities, coupled with supportive regulatory frameworks that expedite the approval process for novel drugs. Furthermore, the rise in leukemia prevalence, along with heightened awareness and early diagnosis, is expanding the patient pool eligible for these cutting-edge therapies. This dynamic landscape presents significant opportunities for stakeholders, ranging from biotech startups to established pharmaceutical giants, to make impactful contributions to leukemia care and patient outcomes.

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Market Scope & Overview

The market report gives thorough information to help readers comprehend the current situation of the industry. The report relied on primary and secondary research, as well as private databases and a paid data source. The market research report sheds light on the history and future of the Leukemia Therapeutics Market business. The report analyses the market size and includes information on market drivers, limitations, and opportunities.

The market research report examines the primary strategies used by top industry players to advance their operations in the worldwide market while maintaining a competitive advantage over their competitors. The Leukemia Therapeutics Market  study also depicts the competitive landscape of the industry's major competitors, as well as the top organizations’ percentage market share.

Market Segmentation Analysis

By Type

Chronic Lymphocytic Leukemia

Acute Lymphocytic Leukemia

Chronic Myeloid Leukemia

Acute Myeloid Leukemia

Others

By Drug Class

Targeted Therapy

Chemotherapy and Immunotherapy

By Distribution channel

Hospital Pharmacies

Online Providers

Drug Store

Retail Pharmacies

COVID-19 Pandemic Impact Analysis

In this Leukemia Therapeutics Market  analysis, the impact of COVID-19 on the market is analyzed at both the global and country levels. According to this analysis, the COVID-19 pandemic and the post-pandemic phase had a significant impact on both the supply and demand sides of the market.

Regional Outlook

The report's accurate data will help market participants make informed decisions about regional expansions and investments. The report looks at the dynamics of the Leukemia Therapeutics Market  in relation to worldwide market conditions.

Competitive Analysis

The data in this section will assist readers in understanding the primary strategies used by leading market players to control the global Leukemia Therapeutics Market . The research report includes a PORTER, SVOR, and PESTEL analysis, as well as an examination of the potential impact of microeconomic market variables. External and internal elements that are projected to have an impact on the company have been studied, presenting decision-makers with a clear picture of the industry's future.

Key Questions Answered in the Leukemia Therapeutics Market  Report

What is the forecasted growth rate, market share, and m market size?

Who are the market's dominant players, and how have they gained a competitive advantage over their competitors?

Conclusion

The Leukemia Therapeutics Market  research report's estimations and estimates examine the impact of different political, social, and economic factors, as well as current market conditions, on market growth. All of this important information will assist the reader in better understanding the market.

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Global Leukemia Therapeutics Market, Forecast 2027

Leukemia Therapeutics Market

Leukemia is a type of blood cancer caused by gene mutation leading to abnormal development of WBCs in the bone marrow and causes leukemia. Leukemia is also caused due to risk factors such as genetic disorders such as Down syndrome, previous cancer treatments, exposure to chemicals, smoking, and family history of leukemia or other blood disorders. The major types of leukemia are Acute Myeloid Leukemia (AML), Chronic Myelogenous Leukemia (CML), and Chronic Lymphocytic Leukemia (CLL), Acute Lymphocytic Leukemia (ALL). The majority of the AML, CML & CLL cases could be observed in adult populations, and ALL could be seen in all age groups. Leukemia treatment is based on its type, age, and ability to cope-up with the treatments. 

Market Size & Growth Rate: 

The leukemia therapeutics market was valued at USD 13.5 billion in 2021 and is projected to reach USD 17.1 billion by 2027, with a CAGR of 7.2% over the forecast period 2022-2027. The growth could be attributed to the return of demand to pre-pandemic levels, increasing authorization of novel & innovative medicines, extensive research, disease prevalence, and immunotherapies. 

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Market Dynamics: 

On account of the growing number of people suffering from leukemia, the leukemia therapeutics treatment market has been driven by technological research & developments, the merging of healthcare organizations and new approvals in the field of blood cancer diagnostics across the globe. 

The Leukemia & Lymphoma Society Therapy Acceleration Program (LLS TAP)-April 2021, announced five new investments in increasing the development of new and improved immunotherapies in Abintus Bio, Nexlmmune, Caribou Biosciences and Immune-Onc Therapeutics for the treatment of leukemia cancer. 

Moreover, raising public awareness about the benefits of preventive healthcare is likely to move the demand for leukemia therapeutics treatment forward throughout the forecast period. Additionally, the Government initiatives and programs at increasing cancer awareness are expected to drive leukemia therapeutics treatment market expansion until 2027. 

Market Drivers: 

The growing research and technological development activities. 

Increasing product approval and product launch by the market players are expected to propel the leukemia therapeutics market, and also technological developments are likely to create various new opportunities that will impact this leukemia therapeutics market growth in the forecast period. For instance, 

In May 2022, Ivosidenib (Tibsovo, Servier Pharmaceuticals LLC) received FDA approval for combination with azacitidine in newly diagnosed AML with a susceptible IDH1 mutation in adults 75 years and older. 

On June 2021, Jazz Pharmaceuticals received FDA approval for a new form of Rylaze (asparaginase erwinia chrysanthemi recombinant rywn) to be developed as part of a treatment for children and adults with ALL 

In October 2021, Kite Pharma received FDA approval for use of the CAR T-cell therapy brexucabtagene autoleucel developed by Tecartus (the first CAR T-cell therapy approved) in adults with B-cell precursor ALL 

In November 2018, Pfizer Inc. received U.S. FDA approval for Glasdegib (DAURISMO), the Hedgehog pathway inhibitor for the treatment of adults suffering from AML 

Increasing incidence of leukemia to boost leukemia therapeutics market growth. 

One of the foremost driving factors influencing the global market is the increasing prevalence of leukemia across the globe, according to the National Cancer Institute (NCI), approximately 1.5% of people were diagnosed with leukemia during their lifetime. Additionally, in the report-2022, the estimated number of living people with new leukemia cases will be 60,650, and the number of death cases will be 24,000 in the United States. 

According to the American Cancer Society-2022, the CLL segment is anticipated 20,160 diagnosis cases including both children & adults in US leukemia therapeutic market, as CLL is the first line of treatment for it followed by AML and CML. 

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Substantial progress has been made against cancer in recent decades. As of 2019, the rate has declined by 32%, mostly because of advances in early detection and treatment for some cancers including leukemia. It reflects largely driven by progress against leukemia cancer. 

Challenges: 

The high cost of treatment and stringent regulatory scenario restrain the market growth. 

High cost of treatment and stringent regulatory scenario restraint the market growth over the forecast period. For instance, the NCI-2022 report estimates that cancer-related direct medical costs in the US were USD 183 billion in 2015 and are projected to increase to USD 246 billion by 2030, a 34% increase based only on population growth and aging. 

The low diagnosis rate of leukemia & lack of proper healthcare facilities in developing countries 

Adverse reactions of leukemia therapeutics 

Competitive landscape:                                                                                                                     

Novartis International AG, Bristol Myers Squibb, Sanofi S.A, Pfizer Inc., Amgen Inc., Takeda Pharmaceutical, Celgene Corporation, GlaxoSmithKline plc, Abintus Bio, Nexlmmune, Exelixis Inc., MorphoSys AG, Otsuka Holdings Company Ltd, AbbVie, Ambit Biosciences corporation, Ariad Pharmaceuticals, Gennzme Corporation, Rpche,  and Others. 

Key Developments: 

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Regional Analysis: 

North America was the largest region in the leukemia therapeutics market in recent years and it is anticipated to capture the highest share of this market over the forecast period 2022-2027, with the U.S. accounting for the maximum contribution and it has well-developed structural healthcare systems. In addition, the high prevalence of leukemia and the rising geriatric population, based on the NCI-2022 report, leukemia represents 3.2% of all new cancer cases in the U.S., and the incidence rate increased in children and adolescents by about 1% per year and was stable in adults ages 20 and older. The presence significant of key players, some of the best research universities, and encouraging new product developments & launches for research lead to more significant assets in the pipeline. For instance, 

In October 2022, The American Cancer Society (ACS) approved funding for 89 new Extramural Discovery Science (EDS) research grants totaling USD 54.3 million. It will fund investigators at 65 institutions across the United States from January 1, 2023.?                                                                                                       

In November 2021, Pfizer Company acquired Trillium Therapeutics for approximately USD 2.22 billion, to enhance its oncology portfolio with the addition of next-generation immune therapies. 

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Acute Myeloid Leukemia Market

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Hematopoietic Stem Cells Transplantation Market 2023-2035 to Grow at a CAGR of ~15% Driving Factors, Size, Revenue, Segments, Expansion, Demand

Global Hematopoietic Stem Cells Transplantation Market Key Insights

During the forecast period of 2023-2035, the global hematopoietic stem cells transplantation market is expected to reach an estimated value of ~USD 6,000 billion by 2035, by expanding at a CAGR of ~15%. The market further generated a revenue of ~USD 2,500 million in the year 2022. Major key factors propelling the growth of hematopoietic stem cells transplantation market worldwide are the increasing prevalence of cancer and the rising prevalence of hematopoietic stem cell transplantation.

Market Definition of Hematopoietic Stem Cells Transplantation

Hematopoietic stem cell transplantation is a process of sourcing healthy multipotent stem cells for replacing the old degenerative cells of the body. After the transplantation of healthy hematopoietic stem cells in the patient’s body, they produce red blood cells, white blood cells, and platelets to repair and replace the patient’s hematopoietic system. The procedure is done to cure a disease, such as cancer, or bone marrow failure, and even in some cases to change the gene pattern. These cells are sourced from the umbilical cord of a baby, peripheral blood cells, and matching bone marrow.

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Global Hematopoietic Stem Cells Transplantation Market: Growth Drivers

The growth of the global hematopoietic stem cells transplantation market can majorly be attributed to the higher number of people suffering from cancer and the deaths attributed to cancer, followed by the growing adoption of hematopoietic stem cells transplantation. According to the World Health Organization, in 2020, around 10 million deaths were caused by cancer and it was known as the leading cause of death in the world. Moreover, every year, around 400,000 children develop cancer in the world. Furthermore, as of 2020, in the world, around 2 million hematopoietic cell transplants have been carried out in the world and there are around 1,500 transplantation centers are set up in the world. On the other hand, the market growth can also be attributed to the rising need for kidney transplantation. In order to stay alive, around 2 million people in the world need dialysis and kidney transplantation.

The global hematopoietic stem cells transplantation market is also estimated to grow majorly on account of the following:

Rising Cases of Cancer

Number of People Suffering from Organ Failure

Rise in Research and Development on Stem Cells

Increasing Number of Hematopoietic Stem Cells Transplant

Development of Customized Drugs

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Global Hematopoietic Stem Cells Transplantation Market: Restraining Factor

Hematopoietic stem cells transplantation is also known to be associated with side effects to the heart, lungs, mouth, and others. Besides this, the cost of the treatment is very high and, in many places, there is a shortage of skilled experts who can perform the transplantation. Hence, these factors are expected to be the major hindrance to the growth of the global hematopoietic stem cells transplantation market during the forecast period.

Global Hematopoietic Stem Cells Transplantation Market Segmentation 

By Transplant Type (Allogenic, and Autologous)

By Disease Type (Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Hodgkin Lymphoma, Multiple Myeloma, and Others)

The multiple myeloma segment, amongst all the other segments, is anticipated to garner the largest revenue by the end of 2035. The growth of the segment can be attributed to the growing cases of multiple myeloma in the world and the surge in use of stem cell transplantation to treat multiple myeloma. In 2020, there were 131,518 cases of multiple myeloma for every 100,000 people, according to the IARC database. Furthermore, in the United States, around 34,000 adults are suffering from multiple myeloma. Moreover, nearly 13,000 people die of the disease in the nation, and approximately 120,000 deaths were reported worldwide in 2020.

By Application (Bone Marrow Transplant (BMT), Peripheral Blood Stem Cells Transplant (PBSCT), Cord Blood Transplant (CBT), and Others)

By Region

The North America hematopoietic stem cells transplantation market is anticipated to hold the largest market share by the end of 2035 among the market in all the other regions. The market size of North America is expected to grow on the account of rising cases of cancer and a higher number of transplants carried out in the region.   The number of organ transplants carried out in the United States increased to 41,354 in 2021. It is approximately 6% higher than the previous higher. Furthermore, in 2022, around 61,000 new cases of leukemia were reported in the United States, and nearly 24,000 deaths were attributed to it.

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The market research report on global hematopoietic stem cells transplantation also includes the market size, market revenue, Y-o-Y growth, and key player analysis applicable for the market in North America (U.S., and Canada), Latin America (Brazil, Mexico, Argentina, Rest of Latin America), Asia-Pacific (China, India, Japan, South Korea, Singapore, Indonesia, Malaysia, Australia, New Zealand, Rest of Asia-Pacific), Europe (U.K., Germany, France, Italy, Spain, Hungary, Belgium, Netherlands & Luxembourg, NORDIC (Finland, Sweden, Norway, Denmark), Ireland, Switzerland, Austria, Poland, Turkey, Russia, Rest of Europe), and Middle East and Africa (Israel, GCC (Saudi Arabia, UAE, Bahrain, Kuwait, Qatar, Oman), North Africa, South Africa, Rest of Middle East and Africa).

Key Market Players Featured in the Global Hematopoietic Stem Cells Transplantation Market

Some of the key players of the global hematopoietic stem cells transplantation market are Escape Therapeutics, Inc., Regen BioPharma, Inc., ThermoGenesis Holdings, Inc., Lonza Group Ltd., CSG-BIO Company, Inc., CBR Systems, Inc., Pluristem Inc., Global Cord Blood Corporation, ViaCord, LLC, Cynata Therapeutics Limited, and others.

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Isocitrate Dehydrogenase (IDH) Inhibitors Market Growth, Trends Analysis Report 2033

The market for isocitrate dehydrogenase (IDH) inhibitors worldwide has a market value of US$ 1.7 billion in 2022 and is anticipated to grow at a CAGR of 33% from 2023 to 2033 to reach US$ 39.16 billion.

Additionally, the development of more potent and selective IDH inhibitors, as well as the expansion of their use into other cancer types, is expected to further contribute to the growth of the market. Bayer and Agios Pharmaceuticals are among the key players in the IDH inhibitors market, with their respective drugs BAY 1436032 and ivosidenib being approved by the US FDA for the treatment of IDH-mutated cancers. These drugs have shown promising results in clinical trials, including high response rates and extended survival in patients with AML.

The IDH inhibitors market is a rapidly growing field with significant potential for the treatment of several types of cancer. Continued research and development efforts, as well as the development of new drugs and treatment strategies, are expected to contribute to the growth of the market.

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Key Takeaways from the Market Study

The global Isocitrate dehydrogenase (IDH) inhibitors market is expected to grow with a 33% CAGR during 2023 to 2033.

Oral route of administration is expected to hold 49% of the market share in 2023 for Isocitrate dehydrogenase (IDH) inhibitors market.

North America is expected to possess 46% market share for Isocitrate dehydrogenase (IDH) inhibitors market in 2023.

Europe Isocitrate dehydrogenase (IDH) inhibitors market size is expected to possess 43% market share in 2023.

“The development of combination therapies and alternative treatment strategies is being explored to further optimize the clinical benefit of IDH inhibitors. This, in turn, is fueling the growth of IDH inhibitors market.” states an FMI analyst

Competitive Landscape

Key players in the isocitrate dehydrogenase (IDH) inhibitors market are Bayer, Agios Pharma, Daiichi Sankyo, Ohm Oncology, Celgene, Philogen S.p.A., Tragara, Aslan Pharmaceuticals, Pfizer, Inc. and Sun Pharmaceutical Industries Ltd.

Bayer is collaborating with other pharmaceutical companies, such as Agios Pharmaceuticals, in the development of IDH inhibitors. The two companies have a joint development and commercialization agreement for ivosidenib (AG-120), an oral small molecule inhibitor of the mutated IDH1 enzyme, which has been approved by the US FDA for the treatment of relapsed or refractory acute myeloid leukemia (AML) with an IDH1 mutation.

Agios’ Pharma lead IDH inhibitor candidate is ivosidenib (AG-120), an oral small molecule inhibitor of the mutated IDH1 enzyme. Ivosidenib works by inhibiting the production of the oncometabolite 2-hydroxyglutarate (2-HG) and inducing differentiation of leukemia cells. Ivosidenib has been approved by the US FDA for the treatment of relapsed or refractory acute myeloid leukemia (AML) with an IDH1 mutation.

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More Valuable Insights

Future Market Insights, in its new offering, presents an unbiased analysis of the global Isocitrate dehydrogenase (IDH) inhibitors market, presenting historical analysis from 2018 to 2022 and forecast statistics for the period of 2023 to 2033.

The study reveals essential insights on the basis of Type (IDH1 Mutant Medullary Malignant Tumor, IDH2 Mutant Medullary Malignant Tumor, Peptides, Small Molecule, Others) Molecule Types (Monoclonal Antibody, Peptides, Small Molecules, Others) Route of Administration (Oral, Parenteral, Subcutaneous) Region (North America, Latin America, Europe, South Asia, East Asia, Oceania, Middle East & Africa)

About the Healthcare at Future Market Insights

The healthcare domain team at Future Market Insights offers expert analysis, time-efficient research, and strategic recommendations with an objective to provide authentic insights and accurate results to help clients worldwide. With a repertoire of over 100+ reports and 1 Billion+ data points, the team has been analyzing the industry lucidly in 50+ countries for over a decade. The team provides a brief analysis of key trends including competitive landscape, profit margin, and research development efforts.

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Key Segments Profiled in the Isocitrate Dehydrogenase (IDH) Inhibitors Industry Survey

Type:

IDH1 Mutant Medullary Malignant Tumor

IDH2 Mutant Medullary Malignant Tumor

Peptides

Small Molecule

Others

Molecule Types:

Monoclonal Antibody

Peptides

Small Molecules

Others

Route of Administration:

Oral

Parenteral

Subcutaneous

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Global Hemato Oncology Testing Market worth USD 4.0 billion by 2024 : Increasing Incidence of Hematologic Cancer

The study involved four major activities in estimating the current size of the hemato oncology testing market. Exhaustive secondary research was done to collect information on the market and its different subsegments. The next step was to validate these findings, assumptions, and market sizing with industry experts across the value chain through primary research.

In the secondary research process, various secondary sources such as annual reports, press releases & investor presentations of companies, white papers, certified publications, articles by recognized authors, gold-standard & silver-standard websites, regulatory bodies, and databases (such as D&B Hoovers, Bloomberg Business, and Factiva) were referred to in order to identify and collect information for this study. According to the new market research report “Hemato Oncology Testing Market by Product & Services (Assay Kits, Services), Cancer (Leukemia (Acute Lymphoblastic, Acute Myeloid), Non-Hodgkin’s Lymphoma), Technology (PCR, NGS, IHC), End-User (Clinical Laboratories, Hospitals) – Global Forecast to 2024″, published by MarketsandMarkets™, the Hemato Oncology Testing Market is projected to reach USD 4.0 billion by 2024 from USD 2.0 billion in 2019, at a CAGR of 14.8%. Browse in-depth TOC on “Hemato Oncology Testing Market“ 77 – Tables 29 – Figures 116 – Pages Download PDF Brochure: https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=262472877 Growth in this market is driven mainly by the rising prevalence of lymphoma & myeloma cancers, growing focus on personalized medicine, and increasing collaborations for developing assays. The services segment accounted for the largest share of the product & services segment in the Hemato Oncology Testing Market in 2018. Based on product & services, the market is segmented into assay kits and services. In 2018, the services segment accounted for the largest share of the product & services segment in the Hemato Oncology Testing Market. The large share of this segment can be attributed to the rising prevalence of hematologic cancers and increasing aging population. Availability of robust infrastructure and high-end equipment for conducting hemato oncology tests are the supporting factors for clinical laboratories segment Based on end-user, the Hemato Oncology Testing Market has been segmented into four types, i.e., clinical laboratories, hospitals, academic & research institutes, and other end-users. Other end-users include CROs and pharmaceutical & biotechnological companies. Clinical laboratories accounted for the largest share of the market in 2018. This segment is expected to grow at the highest rate in the coming years. This is mainly due to the presence of advanced diagnostic equipment such as analyzers and the presence of skilled professionals to perform these tests. North America accounted for the largest share of the Hemato Oncology Testing Market in 2018 North America accounted for the largest share of the Hemato Oncology Testing Market in 2018. The large share of this segment can primarily be attributed to the high incidences of hematologic cancer, aging population, awareness regarding advanced treatment methods, and the strong presence of industry players in the region. These trends are likely to drive market growth during the forecast period. Request Sample Pages:https://www.marketsandmarkets.com/requestsampleNew.asp?id=262472877 Some of the leading players in the Hemato Oncology Testing Market include F. Hoffmann-La Roche Ltd. (Switzerland), Abbott Laboratories (US), Thermo Fisher Scientific, Inc. (US), QIAGEN N.V. (Germany), Bio-Rad Laboratories, Inc. (US), Illumina, Inc. (US), MolecularMD (Ireland), Invivoscribe, Inc. (US), Asuragen, Inc. (US), Adaptive Biotechnologies (US), ArcherDx, Inc. (US), and ARUP Laboratories Inc. (US). Browse Adjacent Markets: Medical Devices Market Research Reports & Consulting Browse Related Reports: Molecular Diagnostics Market by Application (Infectious Disease (Hepatitis, HIV), Oncology, Genetic Testing), Technology (PCR, DNA Sequencing & NGS), End User (Hospital/Academic Laborato https://www.marketsandmarkets.com/Market-Reports/molecular-diagnostic-market-833.html Companion Diagnostics Market by Indication (Breast cancer, NSCLC, Colorectal cancer, Neurological disorders, Infectious Diseases), Technology (PCR, IHC, NGS, ISH), End User (Pharmaceutical & Biopharmaceutical

Companies, Reference Lab) – Global Forecast to 2022 https://www.marketsandmarkets.com/Market-Reports/companion-diagnostics-market-155571681.html About MarketsandMarkets™ MarketsandMarkets™ provides quantified B2B research on 30,000 high growth niche opportunities/threats which will impact 70% to 80% of worldwide companies’ revenues. Currently servicing 7500 customers worldwide including 80% of global Fortune 1000 companies as clients. Almost 75,000 top officers across eight industries worldwide approach MarketsandMarkets™ for their painpoints around revenues decisions. Our 850 fulltime analyst and SMEs at MarketsandMarkets™ are tracking global high growth markets following the “Growth Engagement Model – GEM”. The GEM aims at proactive collaboration with the clients to identify new opportunities, identify most important customers, write “Attack, avoid and defend” strategies, identify sources of incremental revenues for both the company and its competitors. MarketsandMarkets™ now coming up with 1,500 MicroQuadrants (Positioning top players across leaders, emerging companies, innovators, strategic players) annually in high growth emerging segments. MarketsandMarkets™ is determined to benefit more than 10,000 companies this year for their revenue planning and help them take their innovations/disruptions early to the market by providing them research ahead of the curve. MarketsandMarkets’s flagship competitive intelligence and market research platform, “Knowledge Store” connects over 200,000 markets and entire value chains for deeper understanding of the unmet insights along with market sizing and forecasts of niche markets. Contact: Mr. Shelly Singh MarketsandMarkets™ INC. 630 Dundee Road Suite 430 Northbrook, IL 60062 USA: +1-888-600-6441 Email: sales@marketsandmarkets.com Research Insight: https://www.marketsandmarkets.com/ResearchInsight/hemato-oncology-testing-market.asp Visit Our Website: https://www.marketsandmarkets.com Content Source: https://www.marketsandmarkets.com/PressReleases/hemato-oncology-testing.asp

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Acute Myeloid Leukemia Therapeutics Market Size Forecast to Reach $18.3 Billion by 2026

Acute Myeloid Leukemia Therapeutics market size is forecast to reach $18.3 billion by 2026, growing at a CAGR of 7.2% during the forecast period 2021-2026. Leukemia affects the white blood cells and bone marrow. It is characterized by the rapid increase of abnormal blood cells growth that reduces the numbers of fully modified blood cells which leads to the typical symptoms of anemia, bleeding, and high risk of infection. Leukemia can grow along the lymphoid stem cell lines or myeloid depending upon the epigenetic and genetic mutations of the pluripotent stem cells. The leukemia that occurs along the myeloid are known as acute myeloid leukemia and it is a serious condition that is suffered by adult people. Various types of treatments that includes cytarabine, mitoxantrone, tyrosine kinase inhibitors, and imatinib among others are used for acute myeloid leukemia therapeutics. Increasing prevalence of acute myeloid leukemia and increased drug approval rate for acute myeloid leukemia are the major factors driving the growth of the market. Large number of treatment options available for treatment of acute myeloid leukemia and increasing funding for cancer research & development of new therapies is set to further enhance the overall market development of the Acute Myeloid Leukemia Therapeutics Market for the period 2021-2026.

Acute Myeloid Leukemia Therapeutics Market Segment Analysis – By Treatment Type

Cytarabine held the largest share in the Acute Myeloid Leukemia Therapeutics Market in 2020 and is estimated to grow at a CAGR 7.7% during the forecast period 2021-2026. Cytarabine is used for the treatment of different types of leukemia such as acute and chronic myeloid leukemia among others. Owing to its effectiveness in the treatment of acute myeloid leukemia, it is being widely used during chemotherapy process. Macmillan Cancer Support, an organization that is working for cancer have stated that cytarabine is more effective for the treatment of acute myeloid treatment. Chemotherapy kills the cancer cells that metastasized across the different parts of the body. Cytarabine is estimated to register the highest CAGR over the period 2021-2026.

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Acute Myeloid Leukemia Therapeutics Market Segment Analysis – By End User

Hospitals held the largest share in the Acute Myeloid Leukemia Therapeutics Market in 2020 and is estimated to grow at a CAGR 7.4% during the forecast period 2021-2026. Chemotherapy is majorly used for consolidation therapy of acute myeloid leukemia. In hospitals, younger adults are given mainly four rounds of high or immediate dose of cytarabine at monthly intervals and several different regimes are used for older patients. Chemotherapy is usually given in the hospital and recovery time can be spent at home. Hospitals are estimated to register the highest CAGR over the forecast period 2021-2026.

Acute Myeloid Leukemia Therapeutics Market Segment Analysis – By Geography

North America dominated the Acute Myeloid Leukemia Therapeutics Market with a major share of 38.3% in 2020. This is attributed to the increasing research in the field of regenerative medicine for treatment of acute myeloid leukemia. Growing awareness on personalized medicine, high incidences of leukemia, and huge investment in the development of pipeline drug is also increasing the growth of the market in this region.

However, Asia Pacific is estimated to grow at a higher CAGR during the forecast period 2021-2026 owing to the rising investment and increasing cancer awareness. Improving healthcare infrastructure and increasing inclination towards targeted therapies is also increasing the growth of the market in this region.

Acute Myeloid Leukemia Therapeutics Market Drivers

Increasing prevalence of acute myeloid leukemia

Increasing prevalence of acute myeloid leukemia is increasing the growth of the Acute Myeloid Leukemia Therapeutics Market. Acute Myeloid Leukemia begins in the bone marrow and quickly moves into the blood. It can also spread to other parts of the body such as liver, spleen, testicles, and central nervous system. It develops from those cells that turns into white blood cells. Radiation therapy or surgery in cancer patients removes the cancer cells in a specific area but chemotherapy works through the body and gives a better result. According to the estimation done by The American Cancer Society, around 61,780 new cases and 22,840 deaths from leukemia has been reported in 2019.Thus, increasing the growth of the Acute Myeloid Leukemia Therapeutics Market during the forecast period 2021-2026.

Increasing Cancer Awareness

Increasing cancer awareness is increasing the growth of the Acute Myeloid Leukemia Therapeutics Market. This is attributed to the fact that according to the World Health Organization, one third of all cancers are preventable and this can be done by taking a free cancer risk test that identifies the behaviors that can lead to cancer and ways to reduce the risk. As of 2019, 16.9 million cancer survivors are there in U.S. and number of cancer survivors are set to increase to 22.2 million by 2030.Thus, increasing the growth of the Acute Myeloid Leukemia Therapeutics Market during the forecast period 2021-2026.

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Acute Myeloid Leukemia Therapeutics Market Challenges

High Cost of the Therapeutics Process and its Safety Concerns

Some of the factors that are set to impede the growth of the Acute Myeloid Leukemia Therapeutics Market are high cost of the therapeutics process and its safety concerns. Lack of targeted therapies in current acute myeloid leukemia therapeutics and difficult approval process for drugs is also set to hinder the growth of the market during the forecast period 2021-2026.

Acute Myeloid Leukemia Therapeutics Market Landscape

Product launches, mergers and acquisitions, joint ventures, and R&D activities are key strategies adopted by players in the Acute Myeloid Leukemia Therapeutics Market. In 2020, the Acute Myeloid Leukemia Therapeutics Market share is consolidated by the top ten players present in the market. Acute Myeloid Leukemia Therapeutics Market, top 10 companies are Pfizer Inc., Eisai Inc., Cephalon Inc., Celegene Corporation, Bristol,, Novartis AG, Genzyme Corporation, Eli Lily & Company, Amgen, and Gilead Sciences among others.

Key Takeaways

North America dominated the Acute Myeloid Leukemia Therapeutics Market in 2020 owing to the increasing research in field of regenerative medicine for treatment of acute myeloid leukemia and growing awareness on personalised medicines. The Acute Myeloid Leukemia Therapeutics Market scope for different regions will be provided in the final report.

Increasing advantages of biopharmaceuticals over conventional medicines and strong biopharmaceuticals pipeline are likely to aid the market growth of the Acute Myeloid Leukemia Therapeutics Market report.

Detailed analysis of the Strength, Weakness, and Opportunities of the prominent players operating in the market will be provided in the Acute Myeloid Leukemia Therapeutics Market report.

High cost of the therapeutics process and its safety concerns is poised to create hurdles for the Acute Myeloid Leukemia Therapeutics Market.

Related Reports:

A. Acute Lymphoblastic Leukemia Therapeutics Market

https://www.industryarc.com/Research/Acute-Lymphoblastic-Leukemia-Therapeutics-Market-Research-509670

B. B-cell Chronic Lymphocytic Leukemia Market

https://www.industryarc.com/Research/B-cell-Chronic-Lymphocytic-Leukemia-Market-Research-509962

For more Lifesciences and Healthcare Market reports, please click here

About IndustryARC: IndustryARC primarily focuses on Cutting Edge Technologies and Newer Applications market research. Our Custom Research Services are designed to provide insights on the constant flux in the global supply-demand gap of markets. Our strong team of analysts enables us to meet the client research needs at a rapid speed, with a variety of options for your business. Any other custom requirements can be discussed with our team, drop an e-mail to sales@industryarc.com to discuss more about our consulting services.

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Global Trispecific Antibody Market Key Growth Factor Analysis & Research Study 2021-2028

Bharat Book Bureau Provides the Trending Market Research Report on “Global Trispecific Antibody Market Opportunity & Clinical Trials Insight 2028”under  Life Sciences Market Research Reports Category. The report offers a collection of superior market research, market analysis, competitive intelligence and Market reports.

Global Trispecific Antibody Market Opportunity & Clinical Trials Insight 2028 Report Analysis & Data Highlights: • Research Methodology • Global Market Analysis • Global Trispecific Antibody Market Opportunity Assessment: > USD 2 Billion • US To Dominate Trispecific Antibodies Market: >70% • Market and Drug Sales Insight 2024 Till 2028 • Future Market Assessment By Indication Till 2028 • Ongoing Clinical Trials Assessment by Status, Phase and Region • Key Market Dynamics • Competitor Landscape

The advent of monoclonal antibodies has shown to greatly transform the paradigm treatment of several chronic disorders, including cancer. These modalities have shown high penetration in the market owing to their high specificity and selectivity towards the target cell. Despite their robust response in targeting diseases, the role is mainly limited due to their high molecular weight and inability to pass through blood brain barrier. Therefore, continuous research and development has been done by researchers to overcome these limitations.

Recently, the idea of trispecific antibodies has gained momentum in the market. Trispecific antibody consists of single construct which has the ability to simultaneously bind three different antigens at the same time, thus enhancing the efficacy and specificity of treatment. In addition, these have the molecular size one-third to those of monoclonal antibody which ensures high penetrability and ability to cross blood brain barrier. Due to its enhanced functionality, it is believed that trispecific antibodies will result in few side effects and doses. In addition, development of single molecule instead of three has decreased the overall cost of production as well as number of clinical trials.

Till date, no trispecific antibody has been approved for clinical use. However, a wide range of drugs are present in preclinical and clinical development which is expected to enter the market during forecast period. GTB3550 developed by GT Biopharma is one of the leading trispecific killer cell engager (TriKE) which conists of chains of anti-CD16 and anti-CD33 antibodies and a modified form of IL5. Currently, it is being evaluated in phase-I/II clinical trial for the management of CD33 positive acute myeloid leukemia. In addition, Harpoon Therapeutics has also developed several trispecific antibodies utilizing its propertiary TriTAC (Trispecific T-cell activating construct) platform. Apart from this, several other trispecific antibodies has also been developed which are expected to gain approval during forecast period.

The higher specificity of these drugs in targeting multifactorial approach of the disease has encouraged several pharmaceutical giants to actively indulge in research and development of this sector. The pharmaceutical companies enter into alliances or partnerships which provide access to new technologies, and also attract new invesors. The major companies competing in global trispecific antibody market are Sanofi, Numab Therapeutics, Harpoon Therapeutics, and CStone Pharmaceuticals.

At present, researchers have identified the role of trispecific antibodies in cancer as well as HIV. However, with the advancement in science and encouraging response of these modalities it is analyzed that trispecific antibodies will also be utilized in other therapeutic conditions. By segment, cancer is expected to dominate the market attributing mainly to large number of products in clinical trials. Moreover in coming years, the research will be mainly oriented towards cancer therapeutics attributing mainly to their high prevalence and unavailability of effectively curing drugs. The unmet need for the development of targeted therapy and increase in research and development funding by government as well as private sector will also drive the future of novel trispecific antibodies in the management of cancer.

Currently, the global trispecific antibody market is present at nascent stage due to no product approval. However, it is expected that trispecific antibody is anticipated to grow with high growth rates during forecast period. The market will be mainly driven by the rapid increase in the geriatric population which possesses significant risk of developing cancer. Moreover, the unavailability of effectively curing cancer drugs also demands for the development of targeted therapy which will also boost the market. Keeping in mind the high adoption rates of novel cancer therapies, it is expected that US will dominate the market for next 5-7 years. In addition to this, high awareness among the population, presence of large biopharmaceutical sector will also propel the growth of market in this region.

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Top 3 US Pharmaceutical Companies and Their Strategies in US Acute Myeloid Leukemia Market

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US Acute Myeloid Leukemia Market is growing due to advancement in treatment approaches, increase healthcare costs and expenditure, growing investments in Research and Development, and a constant growth in population.

Story Outline

Pfizer Inc.- An American multinational company with the highest annual revenue of around 100 billion US$ in 2022 in the drug market. The company has made significant contributions to the US Acute Myeloid Leukemia Market through a sophisticated, robust, agile manufacturing infrastructure and investment in research and development.

Brystol Myers Squibb- One of the largest American pharmaceutical companies which consistently ranks on the Fortune 500 list of the largest US corporations. The company’s mission is to discover, develop, and deliver innovative medicines that help patients as well as prevail over serious diseases.

Novartis AG- The company with the fourth-largest revenue in the drug market which is focused to deliver high-value medicine that alleviate society’s greatest disease burdens through technology leadership in R&D and novel access approaches.

The US Acute Myeloid Leukemia Market is expected to grow at CAGR of 10.5% in the forecast period 2022-2028.

The Acute Myeloid Leukemia Market of US is driving growth at an amazing level. This surge is a result of advancement in treatment approaches, increases healthcare costs and expenditure, growing investments in Research and Development, and a constant growth in population.

Various pharmaceutical companies are actively shaping this growing market with their strategies and innovations.

This article provides an in-depth look at major pharmaceutical companies with their strategies and innovations.

1.Pfizer Inc.

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Pfizer Inc. is an American multinational pharmaceutical company and headquartered at The Spiral in Manhattan, New York City. The company has made significant contributions to the US Acute Myeloid Leukemia Market through a sophisticated, robust, agile manufacturing infrastructure and investing in research and development.

The company employs more than 30,000 employees worldwide, have 35+ manufacturing sites, 300+ external suppliers, and have reached more than 180 countries. Pfizer tops the list of drug market by achieving a revenue of approx. 100 billion USD in 2022.

Pfizer has made significant contributions to the US acute Myeloid Leukemia Market. Some notable contributions are, in April 2017, the development and approval of a targeted therapy called “Rydapt”, which is an oral kinase inhibitor that targets multiple enzymes, including FLt3, which is often mutated in AML patients. The drug was approved by FDA in April 2017 for use in combination with Chemotherapy.

Furthermore, MYLOTARG is approved in combination with daunorubicin and cytarabine for the treatment of patients aged 15 and above with previously untreated, de novo, CD33-positive acute myeloid leukemia (AML), except Acute Promyelocytic Leukemia (APL).

The company’s purpose is “Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.

The company says that its purpose ensures that its patients remain at the center of all that they do. They live with their purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to their medicines.

Pfizer believes in growing partnerships with innovators to initiate forward great science and continually seek new partners that are actively researching bold scientific ideas. In December 2022, Pfizer announced its collaboration with Gero’s machine learning technology platform to discover potential therapeutic targets for fibrotic using large-scale human-based data.

Pfizer’s continuous clinical trials and collaboration with healthcare institutions and research organizations has majorly contributed in advancing Acute Myeloid Leukemia Market and the development of novel treatment strategies.

2.Bristol Myers Squibb

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The Bristol Myers Squibb Company, is an American multinational pharmaceutical company headquartered in Princeton, New Jersey. BMS is one of the world’s largest pharmaceutical companies and consistently ranks on the Fortune 500 list of the largest US corporations.

The company employs more than 34,000 across more than 86 locations worldwide. The company’s revenue in 2022 was approximately 46 bn USD.

Their mission is to discover, develop, and deliver innovative medicines that help patients as well as prevail over serious diseases. Bristol believes in the power of science to address some most challenging diseases of today's world.

Bristol Myers is majorly known for its contributions to oncology, and immunology and its involvement in Acute Myeloid Leukemia Market with its broader focus on cancer treatments.

The significant development of BMS can be noted from June 2021, Bristol Myers Squibb received approval from European Commission for Onureg, a Frontline oral maintenance therapy for adult patients with acute Myeloid Leukemia who achieved their first complete remission (CR) or CR with incomplete blood count recovery following intensive induction chemotherapy. Onureg is expected to increase sales and product revenue, thereby increasing the US Acute Myeloid Leukemia Market growth.

Furthermore, the strategic cooperation between Evotec and Bristol Myers Squibb has grown in order to create a pipeline for programs addressing more neurological illnesses. In order to find altering therapies for a variety of neurodegenerative disorders, the firms started working together in 2016. The eight-year extension is intended to strengthen the strategic partnership even more.

3.Novartis AG

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Novartis AG is a healthcare company that majorly focuses on the discovery, development, manufacture and marketing of prescription and generic pharmaceutical and eye care products. Novartis offers generic medicines and biosimilars through Sandoz. The company conducts its research through The Novartis Institute for Biomedical Research (NIBR).

Novartis is one of the largest pharmaceutical companies in the world and the fourth largest by revenue in 2022, which was approx. 50.500 billion USD.

The company is functioning in more than 150 locations with around 1,10,000 employees working worldwide.

Novartis's strategy as a focused medicines company is to deliver high-value medicine that alleviates society’s greatest disease burdens through technology leadership in R&D an novel access approaches.

Novartis contribution to Acute Myeloid Leukemia Market includes, FDA approval of Novartis Scemblix (asciminib), with novel mechanism of action for the treatment of Leukemia in October,2021.

Furthermore, through their open approach Novartis is focusing on new technologies to develop next generation therapeutics. Currently, Novartis is working with Orionis Bioscience to find new targets at a genome-wide scale.

By combining development and drug discovery with innovation, they aim to achieve tenuous targets and to launch novel small molecule therapy for Acute Myeloid Leukemia patients more quickly. Thus driving a steered growth for the US Acute Myeloid Leukemia Market.

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Blood Cancer Drugs Market to Generate Exciting Opportunities in the Industry by 2027

The global blood cancer drugs market is anticipated to reach USD 55.6 billion by 2025 according to a new report published by Polaris Market Research. The report ‘Blood Cancer Drugs Market [By Blood Cancer Type (Leukemia (Acute Myeloid Leukemia, Chronic Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Lymphocytic Leukemia), Lymphoma (Hodgkin Lymphoma, Non-Hodgkin Lymphoma (B-Cell Lymphoma, T-Cell Lymphoma)), and Myeloma; By Drugs (Rituaxan/Mabthera (Rituximab), Gleevac/Glivec (Imatinib), Revlimid (Lenalidomide), Velcade (Bortezomib), Tasigna (Nilotinib), Pomalyst (Pomalidomide), Vidaza (Azacitidine), Kyprolis (Carfilzomib), Adcetris (Brentuximab Vedotin), and Others); By Treatment Approaches (Chemotherapeutic, mAbs/Targeted Therapies, and Immunotherapeutic); By Region]: Market Size & Forecast, 2017 – 2025’ provides insights on the current market scenario and the future prospects.

The demand for blood cancer drug is primarily driven by growing death incidences by blood cancer, and continuous innovation for developing novel treatments with the help of several ongoing clinical trials. Moreover, increasing research and development of biological and targeted therapies as treatment will spur the blood cancer drugs market during the upcoming period. However, the high price of drugs and the stringent government policies will limit the growth of blood cancer drugs market during the forecast period.

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Most of the blood cancers start in the bone marrow, where blood is produced. In blood cancer the growth of normal blood cells is dislodged by the uncontrollable growth of abnormal blood cells. These cancerous cells prevent the blood from performing many of its functions. Hence, the existing treatments of blood cancer are being the foundation for developing the new drugs. The steady flow of the blood cancer drugs has created opportunity for research and development in the existing market. For instance, Amgen Inc. received approval for BLINCYTO in July 2017, which is used in treating B-cell precursor Acute Lymphoblastic leukemia. Similarly, European blood cancer drugs market witnessed the approvals of Gazyvaro, by Roche AG that is used in treating advanced follicular lymphoma. Also, novel technologies like CAR-T are likely to be launched this year.

The global blood cancer drugs market is segmented into blood cancer type, drugs and treatment approaches. On the basis of blood cancer type, the global blood cancer drugs market is segmented into leukemia, lymphoma and myeloma. The lymphoma segment is expected to drive the majority market of blood cancer drugs followed by leukemia. The global market of this segment is primarily driven by the increasing prevalence of lymphoma, and presence of effective treatments in the market. On the basis of drugs, the global blood cancer drugs market is further categorized into Rituaxan/Mabthera (Rituximab), Gleevac/Glivec (Imatinib), Revlimid (Lenalidomide), Velcade (Bortezomib), Tasigna (Nilotinib), Pomalyst (Pomalidomide), Vidaza (Azacitidine), Kyprolis (Carfilzomib), Adcetris (Brentuximab Vedotin), and Others. This continuous innovation for treating various sub-types of blood cancers has led to the development of novel types of treatments. For instance, the combination of Revlimid and Velcade has emerged as the preferential drugs in trials for treating multiple myeloma.

The leading companies operating in this industry include Johnson & Johnson Inc., Amgen Inc., Bayer AG., Pfizer, Inc., AbbVie Inc., Roche Holding AG., Celgene Corporation, AstraZeneca, Novartis AG, GlaxoSmithKline PLC, Merck & Co., Inc., and Eli Lily & Co. among others.

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Saudi Arabia Poultry Market to Witness Steady Growth till 2026 | TechSci Research

Strong economic growth and the growing food requirements is expected to drive the demand for Saudi Arabia Poultry market in the forecast period.

According to TechSci Research report, “Saudi Arabia Poultry Market By Type (Broiler, Eggs, Others) By Product Type (Raw, Chilled, Frozen) By Nature (Organic, Conventional) By Distribution Channel (Supermarkets/Hypermarkets, Traditional Stores, Specialized Stores, Online, Others), By region, Company Forecast & Opportunities, 2026”, The Saudi Arabia Poultry market is expected to witness steady growth in the forecast period. The rapid urbanization of the people to live in better conditions and search for employment opportunities is contributing to the growth of the poultry market and enhancing the demand for processed and unprocessed chicken and eggs.

Support of the leading authorities for the development of the poultry market in form of relaxation in income tax, direct subsidies for select food items, interest-free loans, and duty-free imports of raw materials. The leading authorities are providing support to the local manufacturers and taking significant measures to reduce the mortality rate of the bird. An increase in the preference of the consumers for low-fat and high-protein-containing food items is fostering the growing demand of the market. The development of the trade channel and the technological advancements to keep the freshness of the food items and aid in increasing the shelf life of the edible animal food items is fostering the growth of the poultry market.

The increase in the demand for frozen and chilled food items is influencing the demand for poultry-based products in the region. The high demand for the consumption of poultry-based products and the unavailability of quality animal-based edible items in the country and the need to import the animal-based food items are creating lucrative opportunities for the growth of the poultry market. The Saudi government is making heavy investments for the infrastructural development of the country in order to develop the retail and hospitality sector in the country. Under the Saudi Vision 2030, the development of the tourism industry to attract more tourists to the country for religious and other purposes, the government is aiming to develop the poultry sector to meet the growing food requirements.

The COVID-19 outbreak across the world which has been declared as a pandemic by World Health Organization has affected several countries adversely. Leading authorities of Saudi Arabia imposed lockdown restrictions and released a set of precautionary measures to contain the spread of novel coronavirus. The coronavirus pandemic hit the economic status of the country which negatively impacted the growth of the industry. Disruption in the supply chain was observed which adversely affected the supply of raw materials around the country.

However, the growing cost of the poultry feeds and strict quality checks and norms may hamper the Saudi Arabia Poultry market growth in the forecast period.

Browse XX Figures spread through XX Pages and an in-depth TOC on "Saudi Arabia Poultry Market”.

https://www.techsciresearch.com/report/saudi-arabia-poultry-market/7726.html

Saudi Arabia Poultry market is segmented into type, product type, nature, distribution channel, regional distribution, and company. Based on the type, the market can be divided into broiler, eggs, and others. The broiler segment is expected to witness growth in the next five years, 2022-2026. The rise in the demand for whole chicken and its parts and the increasing affordability of the consumers is fostering the growth of this segment. The Hajj pilgrimage attracts a lot of tourists in the country which is expected to fuel the demand and rapid development of the catering service market.  The rise in the development of the construction industry and the liability of the company to provide three meals a day is contributing to the growth of the poultry market as the normal diet in Saudi Arabia includes the portion of animal meat or products.

Almarai Saudi Arabia, Al-Watania Poultry Company, Al-Fakeih Poultry, Al-Berri United Food Co. Ltd, Alwadi Poultry Farms Ltd, Co., Arabian Agricultural Services Company, Arabian Farms Dev.Co.Ltd., Alsalamah Almotatawera Co, BRF S.A, Bayle S.A., Cargill Incorporated, Cherkizovo Group are the leading players operating in Saudi Arabia Poultry market. Manufacturers are increasingly focusing on research and development process to fuel higher growth in the market. To meet evolving customer demand with respect to better efficiency and durability, several Poultry manufacturers are coming up with their technologically advanced offerings.

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“Development of the online commerce channels to improve the reach of products and brand image, the market players are investing huge amounts. The offering of attractive discounts and the facility for home delivery and online payment gateways ate contributing to the growth of the market. The market players are adopting advanced technologies such as 3-D imaging systems to determine the way for optimal cuts and minimize the per-unit cost for poultry processing. The use of latest technologies and the development of efficient distribution channels is expected to propel the growth of the Poultry market till 2026” said Mr. Karan Chechi, Research Director with TechSci Research, a global research-based management consulting firm.

“Saudi Arabia Poultry Market By Type (Broiler, Eggs, Others) By Product Type (Raw, Chilled, Frozen) By Nature (Organic, Conventional) By Distribution Channel (Supermarkets/Hypermarkets, Traditional Stores, Specialized Stores, Online, Others), By region, Company Forecast & Opportunities, 2026” has evaluated the future growth potential of Saudi Arabia Poultry market and provided statistics & information on market size, shares, structure and future market growth. The report intends to provide cutting-edge market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges, and opportunities in the of Saudi Arabia Poultry market.

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[techscimarketresearch]

Saudi Arabia Poultry Market to Witness Steady Growth till 2026 | TechSci Research

Strong economic growth and the growing food requirements is expected to drive the demand for Saudi Arabia Poultry market in the forecast period.

According to TechSci Research report, “Saudi Arabia Poultry Market By Type (Broiler, Eggs, Others) By Product Type (Raw, Chilled, Frozen) By Nature (Organic, Conventional) By Distribution Channel (Supermarkets/Hypermarkets, Traditional Stores, Specialized Stores, Online, Others), By region, Company Forecast & Opportunities, 2026”, The Saudi Arabia Poultry market is expected to witness steady growth in the forecast period. The rapid urbanization of the people to live in better conditions and search for employment opportunities is contributing to the growth of the poultry market and enhancing the demand for processed and unprocessed chicken and eggs.

Support of the leading authorities for the development of the poultry market in form of relaxation in income tax, direct subsidies for select food items, interest-free loans, and duty-free imports of raw materials. The leading authorities are providing support to the local manufacturers and taking significant measures to reduce the mortality rate of the bird. An increase in the preference of the consumers for low-fat and high-protein-containing food items is fostering the growing demand of the market. The development of the trade channel and the technological advancements to keep the freshness of the food items and aid in increasing the shelf life of the edible animal food items is fostering the growth of the poultry market.

The increase in the demand for frozen and chilled food items is influencing the demand for poultry-based products in the region. The high demand for the consumption of poultry-based products and the unavailability of quality animal-based edible items in the country and the need to import the animal-based food items are creating lucrative opportunities for the growth of the poultry market. The Saudi government is making heavy investments for the infrastructural development of the country in order to develop the retail and hospitality sector in the country. Under the Saudi Vision 2030, the development of the tourism industry to attract more tourists to the country for religious and other purposes, the government is aiming to develop the poultry sector to meet the growing food requirements.

The COVID-19 outbreak across the world which has been declared as a pandemic by World Health Organization has affected several countries adversely. Leading authorities of Saudi Arabia imposed lockdown restrictions and released a set of precautionary measures to contain the spread of novel coronavirus. The coronavirus pandemic hit the economic status of the country which negatively impacted the growth of the industry. Disruption in the supply chain was observed which adversely affected the supply of raw materials around the country.

However, the growing cost of the poultry feeds and strict quality checks and norms may hamper the Saudi Arabia Poultry market growth in the forecast period.

Browse XX Figures spread through XX Pages and an in-depth TOC on "Saudi Arabia Poultry Market”.

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Saudi Arabia Poultry market is segmented into type, product type, nature, distribution channel, regional distribution, and company. Based on the type, the market can be divided into broiler, eggs, and others. The broiler segment is expected to witness growth in the next five years, 2022-2026. The rise in the demand for whole chicken and its parts and the increasing affordability of the consumers is fostering the growth of this segment. The Hajj pilgrimage attracts a lot of tourists in the country which is expected to fuel the demand and rapid development of the catering service market.  The rise in the development of the construction industry and the liability of the company to provide three meals a day is contributing to the growth of the poultry market as the normal diet in Saudi Arabia includes the portion of animal meat or products.

Almarai Saudi Arabia, Al-Watania Poultry Company, Al-Fakeih Poultry, Al-Berri United Food Co. Ltd, Alwadi Poultry Farms Ltd, Co., Arabian Agricultural Services Company, Arabian Farms Dev.Co.Ltd., Alsalamah Almotatawera Co, BRF S.A, Bayle S.A., Cargill Incorporated, Cherkizovo Group are the leading players operating in Saudi Arabia Poultry market. Manufacturers are increasingly focusing on research and development process to fuel higher growth in the market. To meet evolving customer demand with respect to better efficiency and durability, several Poultry manufacturers are coming up with their technologically advanced offerings.

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“Development of the online commerce channels to improve the reach of products and brand image, the market players are investing huge amounts. The offering of attractive discounts and the facility for home delivery and online payment gateways ate contributing to the growth of the market. The market players are adopting advanced technologies such as 3-D imaging systems to determine the way for optimal cuts and minimize the per-unit cost for poultry processing. The use of latest technologies and the development of efficient distribution channels is expected to propel the growth of the Poultry market till 2026” said Mr. Karan Chechi, Research Director with TechSci Research, a global research-based management consulting firm.

“Saudi Arabia Poultry Market By Type (Broiler, Eggs, Others) By Product Type (Raw, Chilled, Frozen) By Nature (Organic, Conventional) By Distribution Channel (Supermarkets/Hypermarkets, Traditional Stores, Specialized Stores, Online, Others), By region, Company Forecast & Opportunities, 2026” has evaluated the future growth potential of Saudi Arabia Poultry market and provided statistics & information on market size, shares, structure and future market growth. The report intends to provide cutting-edge market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges, and opportunities in the of Saudi Arabia Poultry market.

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[kritikarehani]

Acute Myeloid Leukemia Market Size, Share, Trends, Epidemiology and Market Forecast 2030

Acute myeloid leukemia (AML) is a clinically and genetically heterogeneous malignancy characterized through clonal proliferation and impaired differentiation of myeloid precursors with various outcomes. Quickest-growing cancer happens when the bone marrow begins to form cells that have not yet absolutely matured as blasts. These cells crowd the bone marrow, stopping it from making normal blood cells and leukemia starts to crowd out the normal white blood cells, crimson blood cells, and platelets that the frame desires. In Acute myeloid leukemia, the bone marrow additionally makes strange crimson cells and platelets. As consequence, the blood cells do not develop, and it gets hard to ward off infections.

Acute Myeloid Leukemia Signs and Symptoms

The symptoms of acute myeloid leukemia generally expand over a week and become an increasing number severely. Signs can include anemia, light skin, constant tiredness, joint infections, frequent bleeding, bone pain, and others.

Acute Myeloid Leukemia Epidemiology

Acute Myeloid Leukemia accounts for <3% of all cancer, and 25% of all leukemia in adults. Worldwide, the incidence of Acute Myeloid Leukemia is reported to be highest in the US, Australia, and Western Europe. The incidence has been near stable over the last years. Incidence continuously shows 2 peaks in occurrence in early childhood and later adulthood. From 2000 to 2003, the US incidence rate in people aged <65 years was only 1.8 per 100,000 persons, whereas the incidence rate in people aged 65 years was 17 per 100,000 persons.

The Acute Myeloid Leukemia incidence rate of 3.7 per 100,000 inhabitants in Europe with a 5-year survival rate of 19%. A cross-national study using US and England data found that the overall risk of mortality for Acute Myeloid Leukemia was 23% lower in England compared to that in the US. However, survival difference was similar in subgroups of sex and age at diagnosis.

According to a study, the yearly average incidence rate of leukemia was 3.68/105 during 2003-2007 in Nanjing. There were no significant differences in gender, the incidence rate was the highest in the group aged 80~ years.

Acute Myeloid Leukemia Treatment Options

Acute Myeloid Leukemia is common leukemia affecting adults and poses a major medical challenge with increased mortality and morbidity. Once diagnosed, the treatment needs to start as quickly as possible. The treatment depends on age, risk factors, and the sub-types of Acute Myeloid Leukemia.

The aim of treatment for Acute Myeloid Leukemia is to cure it and achieve remission of leukemia cells. Traditionally, the standardized treatment was chemotherapy which can be divided into intensive chemotherapy and non-intensive. The intensive chemotherapies are two phases of remission induction followed by post-remission consolidation-based therapy. The induction therapy includes drugs such as Cytarabine, Daunorubicin, Idarubicin, and Fludarabine either alone or in combinatorial doses. Consolidation therapy is presented in such cases where induction therapy failed to work, with drugs such as Etoposide, Amsacrine, and Mitoxantrone.

Acute Myeloid Leukemia Market

FLT3 Inhibitors such as Midostaurin and Gilteritinib; IDH Inhibitors such as Enasidenib and Ivosidenib; and Hedgehog pathway inhibitor, such as Glasdegib; BCL-2 inhibitor such as Venetoclax have recently entered the Acute Myeloid Leukemia market as promising targeted therapies with specific genetic mutations. As the first directed agent that works very well in the elderly population with Acute Myeloid Leukemia, Venetoclax and Glasdegib has opened possibilities in the world of targeted therapy. Gilteritinib, Enasidenib, and Ivosidenib were approved explicitly for relapsed and refractory Acute Myeloid Leukemia, with specific genetic mutations. This spell of new drug approvals has altered the Acute Myeloid Leukemia Market and provided new opportunities.

Various companies such as Actinium Pharmaceuticals, AVEO Oncology, Biodesix, Daiichi Sankyo, BioSight, Helsinn Healthcare, Rafael Pharmaceuticals, Otsuka Pharmaceutical, Cyclacel Pharmaceuticals, and others are developing effective therapies, which contribute to the market size of Acute Myeloid Leukemia.  

There are many competitors in the development phase for the treatment of AML such as Iomab-B CD45 and Actimab-A CD33 (Actinium Pharmaceuticals), Ficlatuzumab (AVEO Oncology and Biodesix), Devimistat (Rafael Pharmaceuticals), BST236 (BioSight), Bemcentinib (BerGenBio), Pracinostat (Helsinn Healthcare) and others.

[jesse-pinkman123]

Theranostics Market Size Share Trends Forecast Opportunity Analysis 2026

Global Theranostics Market Drivers:-

Development of novel companion diagnostic tests to be used with available treatment options is expected to boost the global Theranostics Market growth over the forecast period. Leading manufacturers are engaged in introduction of novel companion diagnostic tests in market. For instance, Illumina, Inc. announced launch of the U.S. Food & Drug Administration (FDA) approved extended RAS panel for identification of patients eligible for treatment of metastatic colorectal cancer with Vectibix (panitumumab) in 2017.

Increasing adoption of companion diagnostic tests by laboratories is further expected to foster global theranostics market growth over the forecast period. BloodCenter of Wisconsin's Diagnostic Laboratories started offering Abbott RealTime IDH1 assay for patients with acute myeloid leukemia (AML) in July 2018. Moreover, Cancer Genetics, Inc. started offering FDA approved companion diagnostic Thermo Fisher Scientific's Oncomine Dx Target - the first Next-Generation Sequencing (NGS)-based Companion Diagnostic (CDx) test in 2017. Laboratory Corporation of America Holdings launched OmniSeq Advance in partnership with OmniSeq for tumor cancers in June 2018.

Partnerships and collaborations by leading manufacturers to develop innovative companion diagnostics is expected to foster global theranostics market growth over the forecast period. For instance, Foundation Medicine, Inc. and Pfizer, Inc. entered into a partnership for development, regulatory support, and commercialization of companion diagnostics (CDx) in January 2018. Moreover, Qiagen, Inc., and Freenome partnered in June 2018, to accelerate the development and commercialization of Next-Generation Sequencing (NGS) tests to enable precision medicine in cancer treatment.

Pierre Fabre and Roche have been working on development of a robust prototype immunohistochemistry assay as a future companion diagnostic test for W0101 (the drug candidate which they are developing together) and extended this collaboration in May 2018. Abbott Laboratories, Inc. collaborated with Celgene Corporation, and Agios Pharmaceuticals, to develop diagnostic tests on Abbott’s m2000 RealTime system that identifies certain genomic mutations associated with acute myeloid leukemia (AML) in 2016. These factors are expected to support global theranostics market growth over the forecast period.

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Theranostics involves combination of targeted diagnostic tests with targeted therapy. It is also known as companion diagnostics, integrated medicine, Dx/Rx partnering, and pharmacodiagnostics. Implementation of theranostics into the patient care plan (in case of selected diseases for which diagnostic tests are available along with respective therapy) may turn into personalized therapy, which could further improve medical outcomes.

Theranostics include use of specific diagnostic test, which shows a particular molecular target on a tumor or any other disease causing agent. Any disease pathophysiology involves specific biological pathways, which are targeted with the help of diagnostic tests. Diagnostic images of the particular molecule then identifies presence of the specific mutation or receptors (in case of cancer), which can be targeted with the help of therapeutic agents. This approach avoids trial and error treatment and could be used to offer patient specific treatment at the right time. Accurate dose calibration and precisely targeted approach could highly be useful in management of chronic diseases such as cancer.

For instance, neuro endocrine tumors can be diagnosed to assess extent of disease via PET-CT (Positron Emission Tomography – Computer Tomography) using Ga-68 DOTATOC (a radioactive positron emitter). Ga-68 targets somatostatin receptor (SSTR2) on the tumor cell membrane, and is injected through vein, which travels and binds to the SSTR2 indication the presence of tumor on PET scan. Furthermore, Ga-68 can be replaced by a therapeutic agent to target the tumor.

However, improperly defined regulations for these tests coupled with inadequate reimbursement facilities are expected to hamper growth of the global theranostics market over the forecast period.

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Global Theranostics Market Regional Insights:-

North America is expected to witness significant growth in the global theranostics market over the forecast period. Presence of leading manufacturers, collaborations, robust research, and development activities, and increasing adoption of companion diagnostics is expected to support global theranostics market growth over the forecast period. Biocartis Group NV and Amgen, Inc. partnered to develop companion diagnostic test for Amgen's drug Vectibix (panitumumab) in 2017. For instance, Genome Canada launched a national initiative for clinical implementation of precision health in June 2018, which would ultimately impact global theranostics market growth over the forecast period.

Asia Pacific theranostics market is expected to witness significant growth over the forecast period, owing to collaborations in the region by global organizations and increasing awareness regarding companion diagnostics. For instance, Qiagen collaborated with Japan based clinical lab testing company, SRL, Inc. for introduction of new companion diagnostics with new drug approvals in August 2018.

Key players of Global Theranostics Market:-

Key players operating in the global theranostics market include Thermo Fisher Scientific, Inc., Beckman Coulter, Inc., Focus Diagnostics, AmeriPath, Inc., Illumina, Inc., F.Hoffmann LA-Roche Ltd., Qiagen NV, Myriad Genetics, Inc., Agilent Technologies, Abbott Laboratories, Foundation Medicine, Inc., and Oxford Cancer Biomarkers, Ltd.

Key Development:-

In 2018, THERADIAG, a company specialized in vitro diagnostics and theranostics entered into partnership agreement with Biogaran to supply its Lisa Tracker kits for Biogaran biosimilar monitoring.

In 2018, Novartis AG, entered into an agreement with Endocyte, a US-based Biopharmaceutical Company which develops targeted therapeutics for cancer treatment.

In 2018 RadioMedix Inc. and AREVA Med LLC, announced the Phase 1 trial for AlphaMedixTM in patients with somatostatin receptor positive neuroendocrine tumors in the U.S. AlphaMedixTM is composed of a somatostatin (SST) analogue radiolabeled with 212Pb, an isotope used for Targeted Alpha-emitter Therapy (TAT).

In 2016, avant diagnostics and Amarantus Diagnostics have signed a letter of intent to acquire theranostics health, a protein analysis service provider.

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