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awlindiathings · 2 years
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Objectives And Functions Of Supply Chain Management
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In order to maximise quality, customer satisfaction, and profitability, the whole manufacturing flow of products and services is managed through supply chain management. It encompasses everything, from the delivery of the finished product to clients. We'll look at the goals and duties of supply chain management in this post. Even in the cold chain logistics using supply chain there are multiple objectives and functions. The following are the objectives of Supply Chain Management:
To Increase the Total Value Created 
The success of the supply chain increases with increasing SCM profitability. The profitability of the supply chain is the difference between the price a consumer pays for a product and what it costs an organization to make and deliver that product to the client.
Improvement in Price and Quality 
This is another crucial SCM goal. Cost-quality optimization and balancing are the goals. 
Finding sources of cost and income 
The only source of income is from the customer. As a result, the movement of information, goods, or money should be properly managed. It is essential to the supply chain's success.
Delivery Improvement 
The SCM attempts to satisfy the customer's requests for assured delivery of high quality goods at competitive prices and with short lead times. In addition, SCM reduces the time needed for ordering and fulfilling seeks to speed up the process.
Demand Satisfaction 
Managing demand and supply is an important yet difficult responsibility for a business or management staff. Its goal is to satisfy consumer demand with effective resources.
Better Utilisation Of Resources
It is another objective of the supply chain management to make better utilisation of the available resources and reduce the cost of the operations. This results in safeguarding the just in time supply while also improving the delivery reliability at the same time. Furthermore, supply chain management is an integral part of the process. The importance of supply chain management can be explained by ensuring customer satisfaction by ensuring right delivery times and pepper sale support.
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rajukumar8926 · 3 months
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Revolutionizing Cold Chain Logistics in India
India's cold chain logistics market is poised for growth, driven by advancements in technology and the need for efficient temperature-controlled transportation. Explore the top 3PL logistics companies in India that specialize in cold chain solutions. Discover how these providers are tackling fragmentation, improving visibility, and ensuring the integrity of sensitive products throughout the supply chain.
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sanjeev3214 · 9 months
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Temperature-Controlled Triumph: Unveiling the Dynamics of the Global Cold Chain Market
In the vast landscape of global trade, the cold chain market quietly orchestrates a crucial role, ensuring the flawless transport of temperature-sensitive goods worldwide. Let's embark on a journey into the dynamics of the global cold chain market, witnessing a narrative of growth, innovation, and pivotal market forces.
The essence: Decoding the Global Cold Chain Market
The global cold chain market is more than a logistical marvel; it's a linchpin across various industries, from pharmaceuticals to fresh produce. In 2022, the market surged to a staggering USD 233.2 billion, driven by a noteworthy compound annual growth rate (CAGR) of 18.6%. This surge echoes the shift in consumer preferences, the e-commerce boom, and the expanding realm of organized retail.
Cold Chain Market Growth: A Symphony of Factors
The growth narrative of the cold chain market resembles a symphony, with various forces harmonizing to create a compelling melody.
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E-commerce Boom: Fueling the Momentum
The surge in online shopping has propelled the demand for cold chain solutions. Consumers now expect temperature-sensitive goods, such as fresh groceries and pharmaceuticals, delivered to their doorsteps in pristine condition. This shift has reshaped the dynamics of the cold chain market, driving robust growth.
Technological Advancements: Reshaping Possibilities
The integration of technologies like RFID and automation has propelled cold chain applications into a new era. From real-time monitoring to predictive analytics, these advancements optimize the entire cold chain process. Efficiency has increased, and the market has witnessed a surge in innovative solutions.
Government Initiatives: Building Foundations
Governments worldwide recognize the importance of a robust cold chain infrastructure. Initiatives to reduce food waste, enhance food safety, and support the pharmaceutical supply chain have been instrumental. Increased investments in cold chain infrastructure have solidified the market's position as a linchpin in the global supply chain.
Market Components: The Heartbeat of the Cold Chain
Understanding the key components of the cold chain is crucial to appreciating its significance and the role each element plays in maintaining the integrity of temperature-sensitive products.
Storage Facilities: Where Cold Chain Begins
At the core of the cold chain are state-of-the-art storage facilities. Refrigerated warehouses and cold rooms provide the necessary environment for preserving product quality. The demand for frozen foods has driven the need for advanced storage solutions, making storage a dominant force in the market with a significant 51.4% share.
Transportation Modes: Safeguarding the Journey
Transportation is the lifeline of the cold chain. Refrigerated vehicles and containers ensure the safe transit of temperature-sensitive goods. This segment, encompassing cold chain transportation solutions, has experienced substantial growth, reflecting the increasing need for efficient transit.
Packaging Innovations: Balancing Quality and Sustainability
Innovations in packaging materials have addressed environmental concerns while maintaining product quality. Recyclable thermal shippers and sustainable packaging solutions have gained prominence, aligning with global efforts to create a more sustainable cold chain.
Monitoring Components: Safeguarding Integrity and Safety
The cold chain's efficiency and safety hinge on advanced monitoring components. Sensors and RFID devices provide real-time data,77 enabling stakeholders to track and monitor shipments throughout the entire journey. This segment, focusing on monitoring advancements, is poised to grow at a rapid CAGR of 22.5%.
Market Segmentation: A Mosaic of Opportunities
Segmenting the cold chain market reveals diverse opportunities and growth areas, each playing a unique role in the market's overall tapestry.
Type-Based Segmentation: Varied Growth Paths
Storage Dominance: Storage solutions maintain a significant market share, driven by the increasing demand for frozen foods.
Transportation Growth: Cold chain transportation solutions continue to drive segment growth, meeting the rising demand for efficient transit.
Packaging Innovations: Innovations in packaging materials, including recyclable thermal shippers, address environmental concerns.
Monitoring Advancements: Anticipated to grow at the fastest CAGR of 22.5%, this segment thrives on technological advancements ensuring shipment integrity.
Temperature Range Classification: A Chilled Symphony
Frozen Segment Dominance: The frozen segment dominates the market, expected to grow at the fastest CAGR of 19.7%.
Chilled Segment Growth: The chilled segment caters to the transportation needs of perishable products, expected to grow at a considerable CAGR of 16.6%.
Application-Centric Analysis: Market Leadership Unveiled
Food & Beverages Leadership: The food & beverages segment commands a significant market share, driven by technological developments in seafood processing.
Pharmaceuticals Growth: The pharmaceuticals segment is anticipated to grow at a considerable CAGR of 20.5%, driven by stringent regulatory norms.
Driving Forces Behind Market Growth: Unraveling the Threads
Understanding the driving forces behind the market's growth provides insights into the factors shaping the cold chain's future.
E-commerce Boom: A Paradigm Shift
The proliferation of online shopping habits has transformed consumer expectations and, subsequently, the demand for efficient cold chain solutions. The organized retail sector in developing economies has amplified this demand, marking a significant shift in consumer behavior.
Technological Advancements: A Techno-Logistical Revolution
Integration of RFID and automation into cold chain applications has opened new avenues for growth. Innovations in warehouse management and refrigerated transportation have contributed significantly to market expansion, fostering efficiency and reliability.
Government Initiatives: A Global Endeavor
Global initiatives to minimize food waste and increase investments in cold chain infrastructure play pivotal roles in shaping the market's growth. Governments worldwide recognize the importance of a robust cold chain in ensuring food safety, quality, and accessibility.
Regional Dynamics: A Global Tapestry The North American market, holding a substantial revenue share of over 34% in 2022, remains a key player. The region offers significant growth opportunities, driven by a large consumer base and increased penetration of connected devices. Meanwhile, the Asia Pacific region emerges as the fastest-growing market, with a projected CAGR of 21.1%. Government investments in logistics infrastructure development and the penetration of Warehouse Management Systems (WMS) co
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sherunsittt · 11 months
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Logistics and the Pharmaceutical Industry
Logistics plays a pivotal role in the pharmaceutical industry, where precision and reliability are paramount. The transportation and distribution of pharmaceutical products, including vaccines, medications, and medical equipment, demand stringent adherence to temperature control, security, and regulatory compliance. Supply chain disruptions can have dire consequences, impacting patient health and safety. Therefore, logistics providers servicing the pharmaceutical sector are entrusted with the critical task of ensuring that these life-saving products reach their destinations in pristine condition, on time, and in compliance with complex international regulations. Meeting the unique challenges of this industry requires specialized expertise, state-of-the-art equipment, and a dedication to the highest standards of quality and safety in the logistics process.
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Cold Chain Logistics: Ensuring Freshness and Safety in Perishable Shipments
In the world of shipping and freight forwarding, there’s a critical sector that often goes unnoticed but plays a vital role in our daily lives – cold chain logistics. This intricate network of temperature-controlled storage, transportation, and distribution ensures that perishable goods, such as fresh produce, pharmaceuticals, and even vaccines, reach their destination with their quality and safety intact. In this blog, we’ll explore the fascinating world of cold chain logistics and how it relies on shipping and freight forwarding, customs clearance, warehousing, and specialized freight forwarding solutions to ensure freshness and safety.
The Cold Chain Logistics Journey
The journey of perishable goods through the cold chain logistics process involves multiple stages, each requiring precise handling and monitoring:
Cold Storage Warehouses: The process begins in cold storage warehouses where products are stored at specific temperatures to preserve their freshness. These warehouses are equipped with advanced refrigeration and monitoring systems.
Transportation: Once the goods are ready for shipment, they enter temperature-controlled vehicles, which can range from refrigerated trucks to specialized containers for sea and air freight. These vehicles maintain the required temperature throughout transit.
Customs Clearance: Customs clearance is a crucial step in international cold chain logistics. It involves complying with customs regulations, obtaining permits, and ensuring that the goods meet all safety and quality standards.
Freight Forwarding Solutions: Freight forwarders specializing in cold chain logistics play a pivotal role. They ensure that the right shipping methods are selected and the goods are transported with the utmost care, adhering to temperature guidelines and handling requirements.
Monitoring and Tracking: Continuous monitoring and tracking are essential. Advanced technology allows stakeholders to monitor temperature, humidity, and other vital parameters in real time. If any deviation occurs, immediate corrective action can be taken.
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Advantages of Cold Chain Logistics
Preservation of Quality: Cold chain logistics preserves the quality, taste, and nutritional value of perishable goods, ensuring they reach consumers in the best condition.
Safety: It prevents the growth of harmful bacteria and pathogens in food and ensures that medicines and vaccines remain effective.
Global Reach: Cold chain logistics enables the worldwide distribution of temperature-sensitive products, supporting international trade.
Reduced Waste: Proper handling and monitoring reduce the risk of spoilage and waste, benefiting both businesses and consumers.
Challenges and Future Trends
While cold chain logistics offers numerous advantages, it also faces challenges like equipment maintenance, energy consumption, and regulatory compliance. Moreover, as demand for fresh and frozen products grows, the industry is witnessing innovations like blockchain for traceability and autonomous refrigerated vehicles for improved efficiency.
In conclusion, cold chain logistics is an indispensable part of modern life. It ensures that the food we eat is safe, the medicines we take are effective, and vaccines reach those who need them. It’s a testament to how shipping and freight forwarding, customs clearance, warehousing, and specialized freight forwarding solutions work together seamlessly to guarantee freshness and safety in perishable shipments, even globally.
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tciexpress · 2 years
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Cold Chain Logistics Companies in India | TCIEXPRESS
TCIEXPRESS is successfully providing temperature-controlled transportation through FTL and Milk Run with GPS and tracer-enabled vehicles to track temperature and vehicle location for safe and secure delivery of products at the end destination. Browse us, the best Cold chain logistics companies in India via our website https://www.tciexpress.in/cold-chain-express.aspx
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trustech · 2 years
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Female Company
Pairing - Shivering Soldier Dunkirk x fem!reader
Summary - You decide to give the shivering soldier some company in hopes to make him feel better, you do indeed.
Warnings - dubcon, handjob, blow job, rough.
Word count - 1.8k
Notes - Shivering soldier Cillian is underrated, also difficult to write so sorry if horrible writing as this felt rushed.
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“Perhaps some female company would make him feel better” Peter, your brother suggested. All six eyes turned onto you, making your heart skip a beat. “Feel less intimidated and what not” Peter added. 
Since you had saved the shivering soldier from the shipwreck, he had been at mute, refusing to show any signs of communication with anyone. He was down below deck, getting warm and hopefully to become more comfortable around these friendly strangers.  
It was risky, you weren’t even really allowed on the Moonstone anyways. But you wanted to help, your father raised you properly, you were a qualified nurse for the army, you were here to help. 
“I’m sure I can be good enough company” George interjected. George didn’t like it, the thought of you being alone down there with the shivering soldier, but that was more out of jealousy than obligation. 
Mr Dawson shook his head towards George, then looked towards you. “I’m sure you’ll be able to make him feel comfortable enough sweetheart” your father gave you a pure smile. “And, God forbid if anything were to happen, we are all right here” Mr Dawson ached, raising his hands slightly at the thought of something bad occurring. 
But your father trusted you, you were a good person who followed pure morals. All your life you’ve helped others, what’s one more soldier to the list? George gave an iffy look but decided to remain silent, looking out the ocean with his fists forming under his sleeves. 
The small door creaked open as you stepped inside. “Hello?” You whispered as you lowered down the small ladder, you closed the small door behind you. 
The shivering soldier was lying on the small, uncomfortable ship bed, a blanket wrapped around his cold body. His eyes were closed but you could tell he was awake. Slowly peeking open, the soldier stared you up and down. The soldier repositioned himself, sitting up on the thin mattress. You sat down next to him, the room was swaying in motion with the waves outside. 
Sitting in silence for a while, you decided to break it. “Is there anything I can do for you? Water? More blankets?” You asked politely. 
There were already such limited services you could provide for him, being on such a small boat and all. You were used to being able to help people, especially in these desperate times, but right now you feel hopeless.  
After a short beat, the soldier mumbled his reply, “I’m okay, thank you”. You tried to read his expression, coming to the harsh thoughts that he didn’t seem to be amused to have you down here with him, that he just wanted to be alone after all, that you were intruding.  
He was beautiful, despite his worn out expression and dirty, wet appearance. There were dark bags around his ocean blue eyes, and a couple of scratches over his face. You felt horrible for him, it was unimaginable what trauma the war can cause upon a man. No one would ever understand how terrifying and ruining his mind had become over this short time. 
“Are you certain?” You checked, you’d hate that he would decline your help by either being too afraid or polite. There was no response from him. “Perhaps if you took off your jacket you could warm up faster” you suggested harmlessly, the soldier looked at you, his mouth was ajar open and eyes dark. 
War tested men’s temptations, it demonstrated how much they really depended on a woman's touch. Men needed something to feel good about in these horrible days, their urges took over their logistics if no one was there to keep them in line. And right now you were defenceless in the beast’s cage, and he was off his chain.
In his defence, you were asking for it. Why else would you ask such a thing twice and then practically beg him to strip? The soldier quickly leant in and kissed you hungrily, his arms snaked around your body to keep you still. You were frozen, not sure how to react to his assault, his tongue slipped down your throat, hands gripping against your lower back as if life depended on it. His left hand moved to your breasts and kneaded them dispairly.  
You’ve been kissed before, only once, but it was nothing compared to this, never so passionate and amorous. 
A moan struggled to break out of your combined lips. Swiftly, he picked up your body and laid you onto your back, not as gently as you could hope, your hand reached for the ache stinging from the back of your head. 
“Be a good little girl, and stay quiet, hm?” He ordered, his hand tapping your cheek to flatter you. 
What else were you meant to do? Call out for help? Start a domestic between an old man, two kids and a war soldier? Even if you did so, what would happen afterwards, you’re on a boat deeply within the ocean. 
The soldier felt your body with his rough hands, he was desperate to feel any touch, but too impatient to take it slow. Unbuttoning your shirt roughly, you were lucky that he didn’t rip off the buttons.  The shape and look of your breasts made him believe he was already in heaven. When was the last time he’s felt a woman’s touch? How many countless nights of him dreaming for intimate touch? His mouth landed on your right breast first, then the left. 
There wasn’t enough time, to properly feel you, to worship your body, to come over and over again. Your bodies felt the friction of the waves rocking yourselves back and forwards. Head in the palms of his hands, the soldier's hips were humping against yours, your legs wrapped around his small waist, he was groaning lowly, unable to contain himself, kissing your neck and side of your face. 
Lying stiff underneath him, you couldn’t help but to moan back quietly, the fabrics between your bodies was too thick to feel the sensations fully, but this is the most touching of a man you’ve ever felt before, your back arched on the mattress. 
“The fuck are you wearing pants for?” The soldier muttered, slapping the side of your thigh harshly. “How am I meant to fuck you without getting caught, aye?” He spat by your ear. 
A lot of people still considered it taboo for women to wear pants, it took away femininity, and in this case, the easy access. 
“M’sorry” you whimpered back underneath him, cheeks all flustered from the embarrassment and overwhelming situation. 
“Guess you’re just going to have to put that mouth to better use” he sighed and sat up, he pulled you down to the ground, you landed on your knees. Repositioning you to be directly in front of him, he flexed his hips towards you. “Do you know how to suck cock?” He asked smugly. 
“N-no” you whispered.
“Ever please a man at all before?” His eyebrow was cocked to you. 
“No sir” you replied and he chuckled. 
“That’s sweet, I’ll be quick anyways” he said with another tap to your cheek. 
He gestured for you to put your hands onto his crotch, you could see the bulge through his damp pants but you didn’t expect it to feel so solid. It was like playing with a knick-knack, your hands travelled all around it, feeling its shape and size. 
“Uh, alright, pull it out now, love” he purred, hand caressing the sides of your head with his eyes closed. 
Your stomach turned at the way he called you love, you didn’t realise how badly you craved that validation. There was this undying small innocent smile on your lips, he looked down to you and gave you a smug smile back and a gentle pat on the cheek.
With shaking hands, you undid his belt and tugged down at his trousers. The soldier ended up helping you, not out of kindness, only restlessness. You gasped as he pulled out his cock, you didn’t realise it could be so – big. The soldier's cock was hairy as the base, had a couple of veins popping out at his length and had a pretty pink tip. If you knew any better about sex, you’d say that he’s already about to burst. 
It was like natural instincts, he didn’t have to say anything, you automatically took his length in both hands, staring from the base and working your way up. He groaned and his head fell back, hands in your hair as you slowly worked your hands up and down his length. In another reality, he would have loved to have you take your time, worshipping his cock. 
“Okay, sweetheart, I need your mouth around me right now” he hissed, leaning his upper body forward easily to push your head towards his member with his hands. 
You pushed against him, your lips an inch away from his tip, okay, this was getting frightening now. The realisation of what you were doing below deck, could be interrupted at any moment, freaked you out. But that didn’t stop him, he pulled harder, making you yelp and your mouth pressed against his member. But you refused to open up for him, he rubbed your mouth and nose around his firm length, your hands pressed against his upper legs in an attempt to push free but it was pointless, you were whining. 
“Fucking open up, you dumb whore” he spat, you mewled quietly, too afraid to catch anyone’s attention on deck. Reluctantly, you slowly opened your mouth and he slipped his tip in. “Ah, fuck” he muttered, the rocking of the boat, thrusted him deeper in and out of your mouth. He had no shame in swearing, muttering and whining underneath his breath, his balls already tightening. “Christ, I’m not going to fucking last-” he was breathless, eyes almost rolling back. 
Forcing your mouth right down to his base, your cries were blocked by his size. There was no space to breathe, your jaw was aching and you were gagging. With how wide your mouth was, you were afraid that your jaw would lock, it was aching, the head of his cock hitting the back of your throat over and over again. Tears were running down your cheeks as he was groaning under his breath, eyes squeezed shut, nostrils flaring and jaw clenched. 
Without a warning, he bursted right down your mouth, his legs shaking slightly, hands tightened around your hair. The soldier bit on his lower lip to silence his moan of pleasure as his cock was spurting out straight into your throat. 
It tasted salty and bitter, your face scrunched up at the taste, but he didn’t pull out his member until you swallowed it all, it was difficult to swallow with his cock covering the entirety of your mouth. Slowly slipping himself out, he tucked himself back into his trousers and ran his hand through his hair. 
Tears were slowly running down your cheeks, you felt your aching jaw softly and sniffled, the soldier pulled you up onto the bed and wiped your face clean with his bare hand. He sighed, looking you up and down. Giving you one last kiss, he murmured to you, “thanks for the company”.
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fatehbaz · 5 months
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They’ve built a “Great Wheel” on the Seattle waterfront [...].
The small timber village became a military outpost in the Puget Sound War [...], [and] soon evolved into a trade gateway, with timber tailings and other industrial trash from Henry Yesler’s mill used to fill in the marshlands [...], atop which migrant laborers raised tents and shanties [...] now working to feed raw materials into the furnaces of the Second Industrial Revolution burning in the East. [...] The first nationwide strike ripped across the country’s railways in 1877, but in Seattle the unrest took on a grim character, as thousands of unemployed white workers rioted against their Chinese counterparts [...]. Meanwhile, [...] local elites rebuilt [...] downtown [...] from scratch, hosting the tallest building on the West Coast alongside other new constructs [fueled] with money gleaned from the supply chains linking eastern capital to Alaskan gold. [...] Today the city - again rebuilt [...] - is seen as one of the primary beneficiaries of the “Fifth” Industrial Revolution in information technology, outshone only by California’s Silicon Valley. [...] The digital was increasingly thought of as somehow "immaterial," sustained by intellectual labor more than physical toil [...].
Silicon Valley myths of [...] "immaterial" labor disguise a more gruesome dynamic in which growing segments of the global labor force are being deprived even of the basic brutality of the wage, instead forced out into growing rings of slums, prisons, and global wastelands. [...]
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Perched alongside a downtown business corridor [...], Seattle's Great Wheel seems to peer out over [...] [the] prophesied “cooperative commons,” an infotech metropolis abutting the beauty of an evergreen arcadia. But travel below Seattle’s cluster of infotech industries and the image appears much the same as that of a hundred years prior - a trade gateway, squeezing value from supply chains by selling transport and logistical support. The southern stretch of the metropolis bears little resemblance to the revitalized urban core of the city proper. Instead of the “cognitive labor” of Microsoft, it is defined instead by the cold calculation of companies like UPS, founded in Seattle when the city was one link in a colonial supply chain built first for timber, then Alaskan gold, then World War. [...]
In south Seattle, this logistics empire takes the form of faceless warehouses, food processing facilities, container trucks, rail yards, and industrial parks concentrated between two seaports, an international airport, three major interstates, and railroads traveling in all directions. Meanwhile, the poor have been priced out of the old inner city, moving southward [...]. [T]hey can be found staffing the airport and the rail yards, hauling cargo in and out of two the major seaports, loading boxes in warehouses [...]. And, beyond them, the shadow stretches out to Washington’s rural hinterlands where migrant laborers staff a new boom in agriculture and raw materials [...] - and further still into America’s long-depressed interior, where the Great Wheel meets its opposite: Memphis, the FedEx logistics city, watched over by a great black pyramid [the infamous Bass Pro Shop pyramid]. [...]
Every Seattle is capable of creating an eco-friendly, “cooperative commonwealth” tended by apps and algorithms only insofar as there is a Memphis that can provide human workers to sort the packages, a Shanghai to build the containers that carry them, and a Shenzhen to solder together the circuits of the machines that govern it all.
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All text above by: Phil A. Neel. "The Great Wheel". Brooklyn Rail. April 2015. Published online at: brooklynrail.org/2015/04/field-notes/the-great-wheel. [Bold emphasis and some paragraph breaks/contractions added by me. Text within brackets added by me for clarity. Presented here for commentary, teaching, personal use, criticism purposes.]
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Monopolizing turds
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Update 31 May 2023: an earlier edition of this article identified the price of Rebyota as $20,000; this was the rumored price prior to Rebyota’s release in December  2022, when Stephen Skolnick wrote the article I referenced. When Rebyota was actually released in 2023, the average wholesale price (AWP) was $10,800. Thanks to Benjamin Jolley for catching this error, and to Stephen Skolnick for getting to the bottom of it.
It’s been ten years — to the day! — since I first started writing about the bizarre, amazing world of turd transplants, in which a sick person receives a microbiotic infusion in the form of some processed poop from a healthy person:
https://web.archive.org/web/20130608030455/http://blogs.plos.org/publichealth/2013/05/29/why-diy-fecal-transplants-are-a-thing-and-the-fda-is-only-part-of-the-reason/
Gut biomes are one of those understudied, poorly understood medical areas that are both very promising and also full of sketchy medical claims from “supplement” companies, influencers, quacks and grifters. But in the decade since I first started tracking turd transplants (formally called “Fecal Microbiota Transplants” or FMTs), a growing body of sound science has emerged on the subject.
One thing that’s increasingly undeniable is that the composition of your microbial nation is related in significant ways to both your physical and mental health. What’s more, as antibiotic resistant “super bugs” proliferate, FMTs are becoming increasingly central to treating dangerous gut infections that otherwise stand a high chance of killing you.
“Eat Shit and Prosper” is Stephen Skolnick’s delightfully named newsletter about poop and health science. Skolnick is a physicist by training, but has a long history of collaboration with Openbiome, a nonprofit that coordinates between doctors, patients and donors to provide safe FMTs:
https://stephenskolnick.substack.com/
In an edition of Eat Shit from last December, Skolnick recounts the amazing history and dismaying future of FMTs. In 2013, the FDA announced it would regulate FMTs as “Investigational New Drugs,” which could only be administered as part of a registered clinical trial:
https://stephenskolnick.substack.com/p/a-monopoly-on-poop
At that point, FMTs were already in widespread use by docs to treat otherwise untreatable cases of Clostridioides difficile (C. diff), an antibiotic resistant bacterial infection that literally makes you shit yourself to death. These doctors were in no position to run registered clinical trials, which meant that they would have to stop using the most effective therapy they had for a potentially lethal infection.
Doctors and patients kicked up a fuss, and the FDA walked back its guidance, announcing that it would exercise “discretion” in enforcing its Investigational New Drug rule, giving a pass to docs who were treating C. diff with FMTs:
https://www.federalregister.gov/documents/2013/07/18/2013-17223/guidance-for-industry-enforcement-policy-regarding-investigational-new-drug-requirements-for-use-of
That’s where things have stood for the past decade or so. The “discretion” rule means that patients could still get FMTs, but their insurance wouldn’t cover it. But even if you had cash to pay for an FMT, your doc probably wouldn’t administer it for anything except a C. diff infection, despite the promising signs that FMT can help treat other conditions, and despite the generally safe nature of FMTs.
If your doc did give you an FMT, chances are good that they sourced their poop from Openbiome. Openbiome recruits very healthy people, gets them to poop in a bag, then processes the poop — removing nonbacterial solids, testing it for pathogens, freezing it, portioning it, and sending it to docs. All this is done at cost, and it’s not cheap: $1–2k/treatment, mostly due to cold-chain logistics (the poop is shipped at -80C).
Despite the cost, and despite the limitations on treatment, the Openbiome method has proved very reliable. Indeed, FMTs as a whole are pretty darned safe, with the most common side-effects being transient gas and bloating. In the past decade, there’ve been a total of six “adverse effects” associated with Openbiome’s 5,000+ procedures, all in severely immunocompromised people, and none conclusively linked to the treatment:
https://www.sciencedirect.com/science/article/pii/S0016508522003511/pdf
A decade into this system, the FDA has taken the next step forward — only it’s actually a step backwards.
During this intervening decade, a pharma company called Ferring has conducted clinical trials on FMTs and received approval for an FMT product called Rebyota. The process for making Rebyota is effectively identical to the process used by Openbiome: collect poop, remove solids, test for pathogens, add glycerol, freeze and ship.
The main difference between Rebyota and Openbiome’s poop is price. While Openbiome charges $1–2k per treatment, Rebyota charges $10,800
That’s some expensive shit!
Fine. Getting Rebyota through clinical trials means that insurers might start covering it, and perhaps some patients will prefer brand-name poop to open-source poop. But as part of the FDA’s approval of Rebyota, the agency also rescinded its “discretionary enforcement” guidance, making it illegal for docs to source their poop from Openbiome:
https://www.fda.gov/regulatory-information/search-fda-guidance-documents/enforcement-policy-regarding-investigational-new-drug-requirements-use-fecal-microbiota
For Ferring, this is a monopoly on shit, one that lets them charge patients $10.8k for poop that costs $1–2k to process. The FDA does not claim that this is being done in the name of safety. Instead, an FDA official told Skonick that the goal was to “incentivize innovation without creating an access crisis.”
That is, the FDA changed its guidance and put nonprofit stool banks out of business because it wants to incentivize pharma companies to perform expensive clinical trials, and it believes that these companies won’t pay for trials if they have to compete with the likes of Openbiome, which would make it impossible to charge 900% markups on poop.
Trials are important! Evidence-based medicine is important! But Ferring’s clinical trials didn’t tell us anything we didn’t already know. FMTs were already the best therapy we had for C. diff. Testing Rebyota against a placebo didn’t tell us anything new — unlike testing Rebyota against the existing therapies, e.g. product from open stool banks.
Such a trial might have given rise to a very different regulatory outcome, because the cure rate reported by Rebyota is much lower than the cure rate from Openbiome’s own interventions:
https://link.springer.com/article/10.1007/s40265-022-01797-x
That is, using the $1k poop from Openbiome seems to be much more effective than using the $10.8k poop from Ferring. But Openbiome, a nonprofit, hasn’t been able to perform the kind of rigorous — and expensive — clinical trial that Ferring funded.
This points to a significant problem with the FDA’s model. The agency wants good clinical data for the medicines it regulates, as it should, It presumes that the only way to get that data is through granting commercial exclusivity to a for-profit, which ends up costing patients vast sums, and locking many patients out altogether.
This creates all kinds of new dangers. 150,000 people/year in the US contract Recurrent Clostridium difficile Infection (RCdI). FMT increases the cure rate by 20% relative to antibiotics alone. That means that if everyone with RCdI gets a poop transplant, 30,000 extra people will get better. That’s a big number!
For well insured people, Rebyota probably represents a cash-savings — if your insurance covers the $10,800 procedure, you might pay $500 out of pocket, which is far less than the $1–2K you’d pay to get an Openbiome poop transplant. But if you’re uninsured or underinsured, the FDA’s new enforcement rules mean that you’re now on the hook for $10,800.
The FDA did carve out a loophole: if your doc or their hospital are willing to prepare the poop transplant themselves, they can administer that. On the one hand, preparing a poop transplant isn’t that hard — some people do them at home, on their own:
https://web.archive.org/web/20211015060558/https://thepowerofpoop.com/epatients/fecal-transplant-instructions/
But on the other hand, there’s been exactly one death conclusively linked to FMT, and it was from one of these hospital-prepared transplants (the patient had just had a marrow transplant for cancer that wiped out their immune system, and the donor had a novel pathogen that the hospital failed to test for).
So the FDA has created a situation where, if you can’t afford a $10,800 proprietary formulation, your only option is to convince your doc or hospital to prepare their own poop transplant, which will cost less than the $10.8k for Rebyota, but more than the $1–2k from Openbiome, which has all kinds of economies of scale. And if you do manage it, you’ll be getting a procedure that has a much worse safety track-record than the Openbiome process that the FDA just killed.
The FDA has an important role to play here, but as with so many policy questions, how the FDA plays that role depends on things that are far upstream from the agency and its decisions. The choice to fund medical trials through the promise of exclusivity — and with it, extremely high margins — puts the FDA in the position of choosing winners in the marketplace: Ferring wins, Openbiome loses.
Ironically, this is the thing that exclusivity is supposed to prevent. By using profit to incentivize medical research, the FDA is supposed to be recruiting the Invisible Hand as its partner in regulation. But exclusivity is incompatible with the idea of medicine as a public good. The tens (hundreds) of millions that Americans will pay for $10.8k poop transplants from Ferring will add up to far more than it would cost to underwrite clinical trials for an open process like Openbiome’s.
The result: both Americans’ wallets and Americans’ guts suffer.
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Catch me on tour with Red Team Blues in Hay-on-Wye, Oxford, Manchester, Nottingham, London, and Berlin!
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If you’d like an essay-formatted version of this post to read or share, here’s a link to it on pluralistic.net, my surveillance-free, ad-free, tracker-free blog:
https://pluralistic.net/2023/05/29/oh-shit/#rebyota
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[Image ID: A poop emoji wearing a top hat and a monocle, posed against a backdrop of e coli bacteria seen through a high-resolution microscope.]
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sunshinemoonrx · 1 year
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Cai, Bedwyr and company
So pretty much ever since this post about the original folkloric magical-warrior Arthur, I've been doodling designs for other characters surrounding him (and that real good art I rb'd yesterday kicked my ass into wanting to upload them finally).
Of the companions of the Welsh version of Arthur, Cai (or Cei/Kei) has to top the list. Most magical guy in the world. Per Culhwch & Olwen dude has heat and cold powers, he can grow giant, he can survive underwater for nine days. He fought a giant cat once. (It's actually kind of interesting that he later was adapted into the boorish, incompetent Sir Kay because of how amazing he originally was; it's the classic anime rival bit where you can show how cool your new OC, Lancelot or whoever, is by having him be better than the existing best guy)
I was already leaning into the "slutty magical anime boys" aesthetic and, with characters like this who only appear once the legendary Welsh versions of the 9th century on get into full swing, I felt more license to go further with that (whereas my Arthur and Trwyth look slightly more down-to-earth because they appears even earlier as small-scale local figures).
So my concept for Cai is that since he can generate heat from his skin so intense no rain can touch him without evaporating, by anime girl character design logic obviously he has to leave his back and shoulders and thighs uncovered since that's where I'm having his wings of magical flame project from.
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The hair gave me a little trouble--I briefly thought I could give him two-coloured hair to reflect his heat/cold thing, but then I remembered one of the popular HeroAca guys is a two-colour-hair fire-ice-powers guy so I hard-swerved away from treading on those toes. In the end I settled on the MILFy ponytail at the bottom since it'd keep his hair clear of his back, since again, it's very logical and strategically important for the skin there to be bare.
The gloves and metal bands, meanwhile, are meant to be like a shadow the hedgehog power-limiter kinda deal, where he can take them off to unleash his full elemental power. That works with gloves but not really the boots, but I didn't want to lose the symmetry, but then! A piece of medieval Welsh poetry gave me inspiration for another function, and a way to make the design hornier I guess.
One of the Triads of Britain refers to the Three Fettered Men of the Isle of Britain: "Because horses could not be obtained that were suited to them, owing to their size; so they put fetters of gold around the small of their legs, on the cruppers of their horses, behind their backs".
Cai isn't one of the three, but in addition to his main epithet "Cai Wyn" ("worthy Cai", or "Cai the Fair", so it's important he's hot you see), he's also known as "Cai Hir" ("Cai the Tall"), which may be a reference to his ability to grow giant, and fits the 'reasoning' in the Triad. So the bands on his legs became fetters of gold, and my idea is he releases his power by breaking the chain to do his Ultraman rise.
A "crupper", meanwhile, seems to be like, an ass-harness? Sure, that fits the vibe we've ended up at. I figured that can be what he slings his sword from, and then spent...a while trying to figure out the logistics of that. So y'know I had to draw his hips and ass a bunch. For science.
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As you can see, there's a couple of attempts to render the leotard as chainmail; one story, Rhonabwy's Dream, describes Cai as wearing mail of pure white rings with pure red rivets, which sounds gorgeous but I dunno how to draw white chainmail so I mostly gave up. He can wear one over the other, I guess?
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In Culhwch, Cai (who is the best sword-maker in the world, naturally) forges a sword for the giant Wrnach Gawr, then kills him with it and takes it, so I figured that'd be a cool weapon to give him. Cai asks if he'd like it to be white-bladed or dark-blue-bladed, and Wrnach answers "whichever way you prefer"; we never find out what that is, so I thought an asymmetrical design incorporating both would be fun.
Anyway, here's another friend: Bedwyr! Precursor to Sir Bedivere, Bedwyr is Cai's constant companion, who "never feared a quest that Cai went on". Do Not separate them. He's the Fast Guy; though he has one hand, he can draw blood three times faster than anyone can with two; by the time you notice he's stabbed you once, he's stabbed you another seven times, etc. He's also noted as the most beautiful man in all the land (except Arthur, and one other guy whose name never comes up anywhere else).
I had kinda wanted to give Cai lots of hair volume but was thwarted by the bare-back thing so I made that Bedwyr's thing, and he's gotta be a spear guy given the above (another fun thing is his spearhead can fly off and stab guys on its own then come back to him). Another Triad calls Cai one of the "Three Diademed Battle-Leaders of the Isle of Britain", but adds after giving the three that "And one was diademed above the three of them: that was Bedwyr son of Bedrawc." So that's why they both have little tiaras, and while I flip back and forth on the look I settled on making Bedwyr's a little fancier and Cai's simpler to conform with the poem.
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So that's how we arrive at what I consider my final designs for these two lovebirds (one poet tells us Bedwyr's death left Cai "heartbroken"); in the end I prefer the sword-harness just looking like a simple belt from the front, and I added some boots? Thigh-socks? Something?? to Bedwyr to break up the design a bit. The asymmetry of them to conform with his tunic's skirt is inspired by Marin from Saint Seiya, who really rocks the asymmetrical leggings.
And on the right is an initial go at Gwenhwyfar, precursor to Guinivere (and I try to respect the Welsh spellings and pronounciations generally, but I may sometimes refer to her as just "Gwen" in this case). I was inspired by a fragmentary dialogue between her and an antagonistic warrior Melwas (who spends half the dialogue trying to fight Cai actually), where he calls her "Gwenhwyfar of the deer's glance", which brought a vision of a spooky lanky cryptid lady with all-black too-long eyes to mind.
The battle of Camlann was said to be brought about by conflict between Gwenhwyfar and her sister Gwenhwyfach, and a blow struck by the latter to the former, but they might also be like...reflections of the same person's good and bad sides or something?? It's all very murky. In any case, I couldn't stop thinking of Gwen as someone who punches dudes, and the main other instance of that in Welsh legends are their versions of "witches", who wear armour and kill with iron claws. Gwen's mother is a member of the Roman nobility, so I thought fuck it, let's get real wacky and ahistorical and dress her like a cestus-wielding gladiator. Roman influence, iron claws, punching dudes, it all comes together.
Oh, and her father is a giant, so I drew a little Arthur to scale at the bottom to show she's inherited some of that too. I wanna draw her more and refine this, make her spookier (one Triad presents her as being three people? Or Arthur just had three wives with the same name? It might just be a pun? Unclear???) But for now, here's one final page of assorted stuff, presented a couple ways up for clarity:
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So there's another Bedwyr; below him, the Cath Palug, the giant cat Cai fights in the poem Pa Gur, which I do intend to do a big funky monster design for, but much like Trwyth in the first post, I had fun doing a human one too. What, am I not gonna draw a catgirl when I can draw a catgirl?
From the other angle, there's Melwas, foe of Cai and Gwen mentioned above. He describes himself as young, and Gwen calls him a "lad of black and yellow", so I made him a twink with dyed hair, but I'll do a more full design later. Probably not before doing Cai's fight with the Cath Palug though.
Caledfwlch, the pre-Excalibur, I drew before, but I did a more ostentatious version here based on its description in Rhonabwy's Dream, where drawing it is like flames leaping forth from the jaws of the serpents whose designs were on it, so blinding no-one could look at it. I like to imagine it having the more humble look until the critical moment when it reveals its true form.
Aaaaand then there's Arthur on a motorbike. (You may have noticed there's one of these way further up in this post in one of the Cai pages) This is just me continuing to think about that idea from the last post about him popping back up in the modern day. Mostly what I orbit around is that he'd defeat whatever evil wizard he was summoned to deal with and then people would be like "so your job is done?" and he'd be like "what? no, the world is clearly in grave peril" and start running around destroying fossil fuel infrastructure. In fact I have a real hankering to make that a comic, but I'd need to be like, an actual artist for that.
So anyway the idea is he gets the spirit of his horse (Llamrei) to inhabit the bike, enabling it to do sick physics-defying stunts. Here's another for the road in fact:
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(Wow, Cat, do you like Kamen Rider or something?)
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solarpunkbusiness · 3 months
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UK startup Sunswap aims to decarbonize the cold chain with its electric, battery, and solar-powered transport refrigeration unit, Sunswap Endurance. Their technology helps logistics firms and food retailers eliminate emissions, reduce costs, and achieve sustainable zero-carbon supply chains. Founded in 2020, Sunswap has raised €12.8 million to help companies reduce diesel pollution and costs, supporting the decarbonisation of transportation.
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findsupply · 5 months
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2024 to learn to use the new refrigeration technology technology to ensure the continuous freshness of vegetable food
With the development of modern society, refrigeration technology plays an increasingly important role in our daily lives. From home air conditioning to commercial refrigeration, from the medical cold chain to food processing, refrigeration technology is used everywhere. In this field, professional refrigeration technology has become the key to promote the development of the industry and bring comfort and convenience to our lives.
The importance of specialized refrigeration technology cannot be overstated. First of all, it provides a comfortable temperature for our living and working environment. In the hot summer, air-conditioning systems can bring us coolness and comfort, and the support and innovation of professional refrigeration technology is indispensable behind these refrigeration equipments.
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Secondly, specialized refrigeration technology also plays an important role in food preservation and healthcare. In food processing and refrigerated transportation, refrigeration technology can extend the shelf life of food and ensure its freshness and safety. In the medical field, cold chain transportation and refrigeration equipment ensure the quality of medicines and vaccines, and play a vital role in disease control and prevention.
The development of specialized refrigeration technology is dependent on technological innovation and continuous progress within the industry. For example, advanced compressor technologies such as Semi-Hermetic compressors, Scroll compressors and Screw compressors, as well as various types of condensing unit products, are all important components of specialized refrigeration technology. The continuous innovation and enhancement of these technologies has brought about a huge improvement in the performance, efficiency and reliability of refrigeration equipment, as well as a better user experience. Next, let's discover the various types of refrigeration compressor models:
Semi-Hermetic compressor, this compressor is compact, suitable for small and medium-sized refrigeration systems, with high reliability, easy maintenance and so on. The company's Semi-Hermetic compressor is widely used in commercial refrigeration and freezing equipment, industrial refrigeration equipment and other fields, well received by consumers.
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Scroll compressor, another product that has attracted a lot of attention is it. This compressor adopts advanced scroll compression technology, featuring smooth operation, low noise and high efficiency. It is widely used in air conditioning, heat pumps, commercial refrigeration equipment and other fields, and can provide reliable refrigeration solutions.
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Screw Compressor, this kind of compressor is suitable for large refrigeration system, with high efficiency and good stability, etc. Screw Compressor is widely used in industrial refrigeration, cold storage, cold chain logistics and other fields, which can provide very powerful refrigeration capacity.
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Reciprocating Compressor is also a common refrigeration equipment, which is used to inhale low-temperature and low-pressure vapors, increase their temperature and pressure through compression, and then discharge the high-temperature and high-pressure vapors. This type of compressor is commonly used in refrigeration systems, including domestic refrigerators, commercial cold storage equipment, air conditioning systems, industrial refrigeration equipment, and more. This type of compressor is usually characterized by simple structure, high reliability, large refrigeration capacity, etc., and is suitable for refrigeration systems of various sizes.
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Condensing Unit, this is in addition to compressor products, various other types of condensing unit products. These units are compact, stable performance, can be widely used in commercial refrigeration and freezing equipment, catering cold storage and other occasions, can provide comprehensive refrigeration solutions.
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In addition to the above, there are more 2024 new refrigeration technology products waiting for you to discover, now immediately click to learn more: https://youtu.be/SlXrf5VmqsE?si=u7y4viIEIax98Oi2
original resource:https://youtu.be/SlXrf5VmqsE?si=u7y4viIEIax98Oi2
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hwyhaul · 2 years
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For shipping temperature-sensitive goods like produce or pharmaceuticals, it’s vital for shippers or freight brokers to work with reliable supply chain partners for their cold chain technologies and logistics needs. Learn more 👉https://www.hwyhaul.com/who-are-the-top-cold-chain-logistics-companies-solutions-3pls-technologies-more/
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The Commercial Refrigeration System Market is projected to grow from USD 54766 million in 2024 to USD 75239.81 million by 2032, expanding at a CAGR of 4.05% from 2024 to 2032.The global commercial refrigeration system market is witnessing rapid growth, driven by several key factors such as rising demand from the food and beverage industry, technological advancements, and an increasing emphasis on energy efficiency. Commercial refrigeration systems are essential for preserving perishable goods, maintaining food safety, and ensuring product quality across various industries. This market encompasses various types of equipment, including refrigerators, freezers, walk-in coolers, display cases, and ice-making machines, used in sectors such as supermarkets, convenience stores, restaurants, and food processing facilities.
Browse the full report at https://www.credenceresearch.com/report/commercial-refrigeration-system-market
Market Overview
The commercial refrigeration system market has seen substantial growth in recent years, driven primarily by increasing urbanization, rising disposable incomes, and changing consumer preferences towards ready-to-eat and frozen food products. In addition, the expansion of the foodservice industry, including restaurants, cafes, and hotels, has spurred demand for efficient and advanced refrigeration solutions.
According to industry reports, the global commercial refrigeration market was valued at approximately USD 30 billion in 2020 and is expected to grow at a compound annual growth rate (CAGR) of around 5% between 2021 and 2027. This growth is further boosted by the ongoing developments in cooling technologies, the need for greener refrigeration solutions, and the increasing awareness of food safety regulations.
Key Drivers of Growth
1. Rising Demand in the Food and Beverage Industry The food and beverage industry is one of the largest end-users of commercial refrigeration systems. The increasing demand for frozen and chilled food products has resulted in a heightened need for efficient refrigeration solutions. Supermarkets, grocery stores, and food processing facilities rely heavily on these systems to store perishable products, maintain their quality, and extend their shelf life. The growth of e-commerce and online grocery delivery services has also driven the adoption of commercial refrigeration systems to meet the requirements of cold chain logistics.
2. Technological Advancements Technological innovations in the commercial refrigeration sector have led to the development of energy-efficient and environmentally friendly systems. New refrigeration units with advanced features such as digital temperature control, smart monitoring systems, and energy-efficient compressors have gained significant traction in the market. The adoption of natural refrigerants such as ammonia, CO2, and hydrocarbons, which have low global warming potential (GWP), is another major trend, in line with global efforts to reduce greenhouse gas emissions and meet environmental standards.
3. Stringent Food Safety Regulations Regulatory bodies across the globe have introduced stringent food safety standards to ensure the quality and safety of food products. These regulations require businesses to maintain proper refrigeration and storage practices to prevent contamination and spoilage. As a result, companies in the foodservice, retail, and hospitality industries are increasingly investing in commercial refrigeration systems that comply with these regulations, further driving market growth.
4. Growth of the Hospitality Industry The global hospitality industry, encompassing hotels, restaurants, and cafes, has experienced steady growth due to increasing tourism and consumer spending on dining out. These establishments require reliable refrigeration systems to store food and beverages safely. The trend of cloud kitchens and ghost kitchens, which are food delivery-only operations, has also contributed to the demand for commercial refrigeration systems to maintain operational efficiency.
Challenges Facing the Market
Despite the positive growth trajectory, the commercial refrigeration market faces certain challenges. The high initial investment required for purchasing and installing advanced refrigeration systems is a significant barrier for small and medium-sized enterprises (SMEs). Additionally, the rising cost of energy and the need for regular maintenance and repairs add to the overall operational expenses.
Moreover, environmental concerns regarding the use of refrigerants with high GWP have led to stricter regulations on traditional cooling technologies. Businesses are now required to phase out older systems and adopt more eco-friendly alternatives, which can be cost-prohibitive.
Future Outlook
The future of the commercial refrigeration system market looks promising, with continued growth anticipated over the next decade. The increasing focus on energy efficiency and sustainability will drive the development of innovative refrigeration solutions. Companies are expected to invest in research and development to create systems that not only reduce energy consumption but also comply with environmental regulations.
Moreover, the growing trend of smart and connected refrigeration systems, which enable real-time monitoring and predictive maintenance, will further revolutionize the industry. As businesses seek to enhance operational efficiency and reduce downtime, the adoption of these advanced technologies will become more prevalent.
Key Players:
Daikin
Johnson Controls
Carrier
Dover
Baltimore Aircoil Company
Blue Star Limited
De Rigo Refrigeration
Fogel
Hussmann
Imbera
Segmentation:
Based on Product Type
Refrigerator & Freezer
Transportation Refrigeration
Refrigerated Display Cases
Beverage Refrigeration
Ice Cream Merchandiser
Refrigerated Vending Machine
Based on Refrigerant Type
Fluorocarbons
Hydrocarbons
Inorganics
Based on Application
Hotels & Restaurants
Supermarkets & Hypermarkets
Convenience
Based on Region
North America
US
Canada
Mexico
Europe
Germany
France
UK
Italy
Spain
Rest of Europe
Asia Pacific
China
Japan
India
South Korea
South-east Asia
Rest of Asia Pacific
Latin America
Brazil
Argentina
Rest of Latin America
Middle East & Africa
GCC Countries
South Africa
Rest of Middle East and Africa
Browse the full report at https://www.credenceresearch.com/report/commercial-refrigeration-system-market
About Us:
Credence Research is committed to employee well-being and productivity. Following the COVID-19 pandemic, we have implemented a permanent work-from-home policy for all employees.
Contact:
Credence Research
Please contact us at +91 6232 49 3207
Website: www.credenceresearch.com
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ref-24 · 2 days
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Efficient Solutions for Managing Temperature-Sensitive Goods in the Cold Chain
Ensuring the integrity of temperature-sensitive goods across the supply chain is vital for industries such as agriculture and pharmaceuticals.
Here are some effective solutions for managing the cold chain and ensuring the quality and safety of perishable products:
 1. Modern Temperature Monitoring Systems
Constant temperature monitoring is essential for effective cold chain management. Advanced systems equipped with wireless sensors and IoT connectivity enable real-time tracking and fast response to temperature fluctuations. These technologies minimize the risk of product spoilage and regulatory violations. Predictive analytics capabilities can also help prevent unnecessary recalls.
 2. Automated Cold Chain Management Software
Adopting software solutions that integrate data for runtime tracking, reporting, and comprehensive analytics can streamline cold chain operations. These systems optimize the use of assets, information, and logistics, enhancing productivity and traceability. In highly regulated environments and for consumer confidence, automated software is vital for ensuring accountability throughout the supply chain.
 3. Smart Packaging Solutions
Proper packaging is key to maintaining the temperature of enclosed goods. Phase-change materials (PCMs) and vacuum insulation panels (VIPs) help regulate container temperatures during transportation. PCMs absorb or release heat as needed, while VIPs protect against excessive internal temperature changes. These smart packaging solutions reduce the risk of temperature excursions, ensuring products arrive in optimal condition[.
 4. Reliable Refrigeration Systems
Reliable refrigeration equipment is essential for maintaining the integrity of the cold chain. Modern refrigeration technologies conserve energy while maintaining required temperatures. Regular maintenance and calibration, along with backup power systems like generators or UPS, guarantee continuous refrigeration even during power outages to safeguard temperature-sensitive products.
 5. Effective Inventory Control
Applying inventory control principles like first-in, first-out (FIFO) helps eliminate stock risks. Accurate demand forecasting enables precise inventory control, reducing unnecessary expenses and storage space. Effective inventory management is a key component of cold chain logistics.
 6. Staff Training and Best Practices
Well-trained staff who adhere to best practices for handling temperature-sensitive goods is essential for maintaining the cold chain. Providing emergency response training and educating workers on proper storage, temperature control, and room management helps avoid errors that could breach the cold chain
By combining advanced technologies, smart packaging, reliable equipment, and well-trained personnel, companies can effectively manage the cold chain and protect the quality of temperature-sensitive products. Refcold India, a leading exhibition showcasing cutting-edge cold chain solutions, offers a platform to stay informed about the latest developments in refrigeration and cold chain technology.
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