#gc and some of the instructions are basically done
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ceausescue · 2 years ago
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been consumed with the idea for the worst programming language in the world. a lisp 2 with clojure syntax, bytecode interpreted. with goroutines. like janet written by a moron, like common lisp written by someone who hates themselves. hand rolled garbage collector that has to deal with all the intermediate objects from immutable types. im tagging like 11 bits out of every pointer, 3 on the small end and 8 suspended in the middle of the top 16, which is a violation of the geneva convention. none of those bits encode the type and im still boxing floats. pretty sure i worked out how to support special environments that compile to totally untypechecked machine code for fast math. came up with an inline assembly thing for it i might just expose to the user. i don't expect ill ever bother with networking
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pxrtalchopped · 3 years ago
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So Shell Feed
one : ✧ prologue
a various! rise tmnt / reader fanfiction. [with textfic and lit!]
Kendra asks you to test out an app for her. Turns out, that app was not hers to let you test. And now you've stumbled into the groupchat of four vigilante, mutant turtles and consequently, their lives.
But seeing as you had just gotten out of a toxic friend group, you were luckily in dire need of a new one! So fun, how these things turn out for the better.
Posting on ao3, wattpad, and now tumblr! I hope the image formatting works omg! Enjoy!
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Your first day of Junior Year - yippee - and you started it like any other:
Getting work done, which consisted of the same icebreaker papers like any other classroom, doodling random scribbles in your sketchbook till the clock hit next hour, and passing between hours by blasting sped up tiktok songs through your earbuds because fuck talking to people irl.
Don't get me wrong, you weren't an outcast or anything. Sure, you had interests the popular kids might not have been into (take your embarassing and reawakened FnaF phase last year-) but you were widely liked, if not, then not necessarily disliked, by most of the people in your classes.
This was kind of a given, as you've had school with a good handful of these kids in your previous years.
Take Kendra and her little crew, for example. Kendra, Jeremy and Jase had been found in almost every tech class you took as a kid. (Ez school credits you just worked off instruction books) And ignoring their incessant bickerings amoungst eachother, or the ocassional cocky and narcissisticly snide remarks they'd give you if you asked them for help - they actually quite liked you.
Liked you is a nice way of saying you were an easy target for spreading havoc that wouldn't be traced back to them.
Did you know this? No. But that wasn't your fault, you're just a little optimistic about their underlying evilness that they're surprisingly so good at hiding from faculty.
"Hey, ___!" she would coo at you, "our club is entering an app contest, and we need some people to test it out. Can't make any reviews ourselves since they'd call us out on bias, ya' know?"
- All this to say, you weren't at all suspicious when Kendra walked up to you [Jace in tow and Jeremy nowhere to be seen] with a pleasant smirk amoung her bright blue lips, and a cheery tone to boot.
-: ✧ :-  
She put an arm around your shoulder. Her silk jacket was really cold and she smelled like mint, a scent you found common in her clubroom. Maybe it was her signature that she threw across the room every day.
In front of you, she pulled her free hand out with her phone to showcase the club's aforementioned "app".
It seemed to look exceedingly similar to Funstagram.
"Uhh.."
"Don't mention what it looks like, this is just a wip - references were needed for beta," she spoke fast and mumbled, similar to the last three seconds of a commercial as if to help you ignore the blatant copyright.
"Basically what we need you to do is make an account, converse with the... other volunteers we asked, and in about a month or so let me know how it goes!" While talking, she meagerly scrolls through the app, showing you all the functions and controls.
Then, she sends the app's downloadable apk to your phone and explains that your help would be compensated.
You weren't interested until that last part, so you hurriedly downloaded it before the next period started and got to fuckin' work.
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Now, when you typed "themaincharacter" as your username you weren't necessarily thinking anything cocky, you just thought you were being funny and a little cute. No one should give it a second thought, right? You'd be fine.
You needed a profile picture.
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Fucking perfect.
And now you just had to look at the explo- oh what the fuck?
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Okay... randomly added to a gc immediately after creating an account. That's chill.
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You felt bad for BootyyyShaker9000. Dude looked like he was about to have an aneurysm.
Or.. I guess typed like it. Yknow.
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Okay, so they're kind of funny. But you're still insanely confused and they're responding exponentially fast - you're about to get a headache.
Still, you were curious about them. You want to be cautious and polite, so better not tease them in case they're trigger happy with the kick button.
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....You're kind of stupid.
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Oh, okay, they're much chiller than you thought! And also just as stupid as you!
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Not that you didn't register their names by now, but at least you're getting somewhere with your confusion. You're still a little guilty for the purple one.
... purple guy?!!!?!? DID YOU GET SUCKED INTO FNAF?!?!
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The teacher was looking at you, so you decided to put your phone away for the rest of the class.
You could feel your phone vibrate with about 20 more messages before the bell rang.
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Okay, sweet. If being accepted into a group of weird nerds online [who had just literally doxxed you] wasn't enough to leave you on edge, the blackmailing threat of some unknown stranger definitely set you in a sturry.
You had a handful of guesses as to who 'April' was. You knew about three April's personally from your school but none seem the type to talk to guys of this... energy. You made a note to be extra cautious tomorrow; already planning your inconspicuous oversized hoodie and baggy sweats to wear tomorrow.
You'll look like a major red flag or depressed college student buttttt at least you'll be harder to spot in a crowd!
You turned your phone off as you headed out the doors of the school. The battery was getting pretty low anyway. Your guess? Kendra totally gave your phone some virus to get dirt or probably destroy the group of guys you'd just become friends with.
You only had a few hours left before the day ended but it was most likely going to be filled with chores and applications to a part time job now that summer's over - so your schedule was pretty low on free time.
Not to mention now you have to wake up early for your second day of school. Early hours was not something you missed in July.
...All this to say, knowing the person you are, you couldn't risk hopping back in the group chat for the rest of the night. You'd hopped on your phone last year and it would take you till 4 AM before you actually went to bed only to wake up two hours later to get dressed for school.
Oh, you missed summer. Oh, you missed lonely, miserable and depressing summer so so bad.
-: ✧ :-  
Word count: Around 1.1k, not counting the texts.
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louistourinfo · 6 years ago
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I would love to plan a rainbow/light project for my show but I don't even know where to begin đŸ˜„ do you have any tips?
hi nonny!!! I’ve done this a couple of times and most importantly i recommend finding some people going to your show who are willing to help! we’re going to be making GCs for shows so you could try and find people through that!
i don’t know if you want to light the whole venue up (like at harry’s arena shows) or if you want to have as many people as possible waving around mini flags (imo the first would be easier if the venue is all seated and the second easier if its all GA, if its a mix then just take a pick). 
but basically for the first option you need to promo promo promo!!! make a diagram and spread it on here, on twitter, the facebook event, and then print out flyers you can stick up at the venue to make sure everyone sees it. even doing this (again this is my opinion) you’re best bet would probably be to print out coloured pieces of paper w/ instructions to hand out at the venue because people are inherently lazy and cbf downloading a coloured photo or finding their own piece of coloured paper
for the second option you’ll have to bulk buy a bunch of flags essentially which is obviously going to be more expensive so obviously if you can get a group willing to chip in some money that’ll be way less of a burden. there are some websites where you can bulk buy mini rainbow flags for like 10 cents per flag which is honestly a bargain BUT you then have to put them all together- you have to put the flag on the stick and then attach info about the project somehow (we stapled paper on when i did it for hslot 2017), and then you obviously have to hand them out at the show (for GA i recommend just going along the queue some time in the afternoon, for seated maybe go down the aisles and hand them out if you can?). this obviously ends up being a fair amount of time and money so it really is up to you- anything will be appreciated by everyone
and ofc if you or anyone else has any questions about rainbow projects!!! i’m clearly happy to rant about it and help in any way i can i love! this! stuff!!!!
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dong-hyucks · 8 years ago
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7, 19, 92, enemies to lovers AU for nct jaehyun!! :-) congrats on 1000 once again hehe 💓 -đŸŒ»âœš
Jung Jaehyun ; “I dreamt about you last night.” , “Can I hold your hand?” , “I want you to be happy.” + Enemies↣ Lovers!AU
Prompts here.Masterlists
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wow what a bias wrecker
okay so some backstory
you and jeffrey over here have known each other since he got back from america
everyone fawned over him when he got back
you were probably like,, the only one at school who got tired of his little “i lived in america, that’s why i’m here, man!!” joke
you: we get it can you stop now
when he found out you were annoyed by him in general he was a bit confused
he’d never spoken to you before so he thought your disliking of him was a bit dumb
you found out because his friends have loud mouths
which only fueled your hatred oops
because you thought he was calling you dumb behind your back
anyway after you guys graduated
you didn’t see each other much
that is
until you became a makeup artist for sm
the gods were against you because you were assigned to nct
you couldn’t do anything about it tho because it was a good job and you’d rather not get fired
besides, you could tolerate the other boys (for the most part)
this little hatred is a bit one sided
he just likes to mess with you but he doesn’t hate you
like he’d take a lipbalm thing from your bag without you noticing
you’d know it was him but he would play innocent
he would put it back once you turned away tho
“see!! it’s right there”
you rolling your eyes out of your head
whenever it was his turn to get his makeup done or his hair fixed
you had to refrain yourself from making him look like a clown
even being so close to his face infuriated you smh
the boys didn’t really see why you ‘disliked’ each other
like they’d interrogate jaehyun after witnessing him steal your makeup supplies a few times (always giving it back ofc)
he’d never have a legit answer??
“it’s funny to see [Y/N] get angry they’re like a cat lol”
“jae that’s not–”
and then if they’d ask you about it
which was a mistake
the entire time you did the person’s makeup (probably taeyong oml) you’d literally be listing the reasons why jaehyun irritates you
ty: never again
taeyong would tell jaehyun about what you said and he’d be like ???
“they aCTUALLY DISLIKE ME??”
like he thought you had gotten over your resentment from school and you were just playing along
slow child, he is
so after that he’d kind of just lay low
he wouldn’t steal anything anymore or make any teasing comments
which you were half grateful for but at the same time it was weird not glaring daggers at him practically every day
now that he wasn’t playing around with you, you kind of realized how much of an angel he was
bUt you were too prideful to step down 
so you kept your distance
which the boys noticed like right away
they probably made a gc about you guys tbh
anyway now that you weren’t glaring at him 24/7 or making any snarky remarks
jaehyun was able to look at you without feeling like you weren’t going to bite his head off
he started noticing some things
like how you rake your hand through your hair when you’re getting stressed over the makeup
or how you cover your mouth when you laugh (if you don’t do this then read the bold lol)
or how you’re able to laugh comfortably around the boys
and how you bite your lips when you’re concentrating on doing makeup admittedly he got caught staring at your lips by yuta 
and the cute way you furrow your brows together
you’re so different around others than when you’re with him
with him you just stay quiet and don’t say much unless you’re instructing him to move his face in whatever way
but with the boys and with the other staff members
you joke around a lot
and smile easily
he found himself wanting to see you do that in front of him
after like a month of admiring you from afar it kind of just hit him like
“i??? like??? [Y/N]???”
he wouldn’t be that surprised with himself considering the fact he had started to search for you in a room whenever he entered
and the fact that seeing you made him feel all tingly
he’d be kind of nonchalant about it but at the same time he’s torn over whether or not he should confess
he still believes you hate him honestly
he texted johnny about it and ranted for like an hour talking about the pros and cons of confessing
he also fawned over you a bit
however
he made a grave mistake
he accidentally texted yuta and not johnny
rip jung “jeffrey” jaehyun
all of the members, including the ones who hadn’t debuted yet + jaemin, knew of his crush within the hour
half of them would just dismiss it and go one with their lives
the other half were devious and made a plan
a majority of that other half were the dreamies tbh
they got updates on your interactions with jaehyun from donghyuck
occasionally mark
so basically, the dreamies except for the hyung line + yuta came together to make a plan (with doyoung subtly giving ideas smh what a snake)
in hindsight they realized the plan was dumb but hEy it worked
so basically
the boys hid your really expensive makeup palette (i know nothing about makeup sorry)
right before the boys (including the dreamies) had to go on a broadcast
smart idea guys, very smart
so basically you got really worried
because you and the other makeup artists shared that palette because it was gigantic
when it got to the point where the other artists were getting impatient
you were the youngest out of all of them yet you were trusted with the most expensive thing lol
jaehyun saw you freaking out and went over
he didn’t even think about it like the moment he saw your eyes glaze over he kinda sprinted to you
took you out of the room, away from the crowd of people, and into a spare room
you were still freaking out and now you were just “jaeHYUN LEMME GO I NEED TO GO FIND IT–”
he’d literally just hug you and rub your back
he wouldn’t say anything
you’d calm down a bit but you were still worried
jaehyun noticed and frowned
“can i hold your hand?” 
you’d kind of just pull away and give jaehyun a weird look
so he just took your hand and interlaced his fingers, sending you a gentle smile
your heart would actually be pounding
you were confused
why was he acting like this? you didn’t know
so once you calmed down immediately he’d take you back into the room and help you search for it because it’s easier to find things with a calm mind (is it? idk)
and yet
there it was– in jisung’s arms
you couldn’t even be mad because he looked so sorry about it
so basically you and the other artists were rushing to get the boys makeup done but it’s alright cause they’re going to look great no matter what you do
you went home that night with jaehyun on your mind
like you were conflicted
so you texted jaehyun for answers
your texts were really formal because even tho you had his number you never really texted him before
like proper punctuation, grammar, everything
“Hey
 why did you do that? Earlier today, I mean.”
jaehyun was probably on his phone when he got the text
he legit counted to ten before answering your text
“wdym?”
he obviously didn’t care as much for formalities as you did
“You know what I mean.”
you know that feeling you get when you see a speech bubble and it just disappears and then reappears again
yeah that’s how you felt
the speech bubble kept appearing and disappearing for a straight three minutes before he finally sent anything
“i want you to be happy.”
you may or may not have left him on read
‘Read 11:39 PM’
you had jaehyun staying up all night over that wow
that night you didn’t get much sleep
but when you did fall asleep you had a dream
a certain someone was sitting beside you at a table
apparently you were studying, just like you did in school
he merely turned to you and smiled, resting his hand against his cheek and outright staring at you lovingly
then you woke up
you screamed into your pillow when you realized how you felt about that someone
“i like jaehyun oh my god”
you stayed in bed shook for so long you were almost late for work
you saw jaehyun in the elevator and literally spun on your heel to take the stairs
he chased after you like the drama character he is
“wait, [Y/N]!”
when he caught up to you he was panting
which confused you because he literally just ran down a hall??? like you do very complicated and tiring (yet amazing) dances man c’mon
“please don’t avoid me,” he pleaded with a sad look in his eyes
you didn’t answer because you knew you’d die if you looked into his eyes
this made jaehyun feel worse because he thought he upset you again
“can you tell me what i did wrong?”
without even thinking you blurted out, “i dreamt about you last night, okay?”
um no
not okay
realizing what you just said you tried to run away again
he didn’t let you, keeping a firm grasp on your wrist (without hurting you)
“you dreamt about me??” he would ask, astonished
you nodded bashfully; you couldn’t take it back anyway, he’d know you were lying if you said no
“how do you feel about me?”
hoo boy jaehyun straight forward much
you practically glued your lips shut, afraid of revealing another thing you would’ve rather kept secret
he knew you weren’t going to answer so he just continued anyway
“i like you”
your jaw dropped
“i’ve liked you for a while now, and it’s okay if you don’t feel the same, i just wanted to tell you–”
he stopped when he felt your arms wrap around his torso
you covered your face using his chest/neck (idk depends on your height) because you could feel your face getting hotter
you couldn’t see but he was blushing too
“i like you too, idiot.”
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yotesgc · 8 years ago
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COMING SOON: yotes discord server
hey guys its kerrianne @nilliamnylander and i’m currently setting up the discord server for the yotes gc so if you’re interested pls like/reblog this post and/or send a message/ask to this blog (or to @nilliamnylander)!
i’m really excited about this and it’s almost ready (like 95% done thanks @ finals). this server should be up by tomorrow (sunday may 7, 2017) i’m just making sure the server looks pretty and i’ll have more info posting very soon!
but for now if you’ve never used discord or never even heard of it here’s some info:
(most of this is taken from @theleafsgroupchat​ just modified)
first you’ll need to download Discord (available on the google play and app stores there’s some awesome desktop apps too!) or pull it up in your browser and make an account. Super simple, it will require your email but you won’t need to hand that or your phone number out in order to add friends!
Once you’ve created an account you’ll need to follow the link that you will receive. If you’re link does not work, you’ve run out of time, or run into any other trouble, please send this blog (yotesgc.tumblr.com) an ask or message and we’ll resolve the issue.
This link should prompt you to join our server, and once you’ve accepted you’ll officially be a member!
At this stage feel free to maneuver around the interface, and familiarize yourself. You should see a bar on the left side of your screen with an icon for the leafs group chat server. If you click on that icon a list of text channels should appear. You’ll notice that you are automatically moved into the #welcome channel. Here you should find a pinned message explaining the uses for this channel. Follow the instructions! This is where you should test out the messaging capabilities. Part of your first post should include your age (or if you dont want to post your age, just mention whether you’re over or under 18 as that is the key to the different roles)
After you’ve been assigned your role, you should be able to see at least one new channel. Feel free to move into it and say hello.
Try out the other channels! Most of them will have a pinned message to show you what the channels are used for, and most of the titles should be self-explanatory.
That’s the basics! Take advantage of the message systems here on Tumblr, or use our #help channel on Discord if you have questions!
Discord has amazing Direct Message features, and feel free to send the moderators any questions or concerns you have!
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flyersgc · 8 years ago
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COMING SOON: flyers discord server
hey guys its kerrianne @nilliamnylander and i’m currently setting up the discord server for the flyers gc so if you’re interested pls like/reblog this post and/or send a message/ask to this blog (or to @nilliamnylander)!
i’m really excited about this and it’s almost ready (like 95% done thanks @ finals). this server should be up by tomorrow (sunday may 7, 2017) i’m just making sure the server looks pretty and i’ll have more info posting very soon! 
but for now if you’ve never used discord or never even heard of it here’s some info: 
(most of this is taken from @theleafsgroupchat just modified)
first you’ll need to download Discord (available on the google play and app stores there’s some awesome desktop apps too!) or pull it up in your browser and make an account. Super simple, it will require your email but you won’t need to hand that or your phone number out in order to add friends!
Once you’ve created an account you’ll need to follow the link that you will receive. If you’re link does not work, you’ve run out of time, or run into any other trouble, please send this blog (flyersgc.tumblr.com) an ask or message and we’ll resolve the issue.
This link should prompt you to join our server, and once you’ve accepted you’ll officially be a member!
At this stage feel free to maneuver around the interface, and familiarize yourself. You should see a bar on the left side of your screen with an icon for the leafs group chat server. If you click on that icon a list of text channels should appear. You’ll notice that you are automatically moved into the #welcome channel. Here you should find a pinned message explaining the uses for this channel. Follow the instructions! This is where you should test out the messaging capabilities. Part of your first post should include your age (or if you dont want to post your age, just mention whether you’re over or under 18 as that is the key to the different roles)
After you’ve been assigned your role, you should be able to see at least one new channel. Feel free to move into it and say hello.
Try out the other channels! Most of them will have a pinned message to show you what the channels are used for, and most of the titles should be self-explanatory.
That’s the basics! Take advantage of the message systems here on Tumblr, or use our #help channel on Discord if you have questions! 
Discord has amazing Direct Message features, and feel free to send the moderators any questions or concerns you have!
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Best Dental Clinic in Chennai
We always want the best in life and the same applies when you are in need of a dental clinic near you. When in need of a dentist for the first time in a new city or a new location, in most instances, one opts for the most popular choice in the neighbourhood or via referral. The internet offers a plethora of information with the complete listing of the best dental clinic in Chennai and Pondicherry for every location within the city.
Most of the listed dental clinics nearby, often provide a very rosy picture to potential patients about their services, expertise, etc. How then does one make a pick of the best dental clinic in Chennai among the choices? Dental treatment is also commonly perceived as expensive. With corporatization in healthcare, the standard of dental healthcare has improved, but there are still many dental clinics in every neighbourhood making it difficult to choose the best dental clinic.
We trust that your search for the best dental clinic in Chennai will end with a better understanding of the points to consider while choosing the best dental clinic near you. Dr.Smilez is one of the best dental clinics in Chennai, where we aim to provide the best possible care at the same time making your dental treatment as affordable as possible without compromising on the quality of treatment.
We have detailed some discussion points for you to help you in your search for the best dental clinic in Chennai and also on how Dr.Smilez is different from other dental clinics.
1. Standard of Infrastructure & Materials
Modern dentistry is dependent a lot on the quality of dental materials and equipment used. While the common man can make a rational judgment on the standard of equipment availability, it is impossible to differentiate the materials that are used for dental work. Most of the dental clinics in Chennai have all the basic armamentarium, but the biggest differentiator is the standard of dental materials used across these clinics. While even China made materials are technically “Imported”, one must understand the global brands of dental materials available and insist on its usage. After all, what is put in the mouth accounts for overall health also?
At Dr.Smilez we use only standardized global brands of materials such as 3M, Ivoclar, GC, Coltene, Nobel Biocare, etc., and also constantly monitor the expiry date and upgrade to the latest and the best materials available from time to time. Almost all dental materials used are imported from USA, Germany, Japan, etc and of world-class standards. This ensures that treatments are long-lasting and more durable.
Best Dental Clinic in Chennai
2. Sterilization and Disinfection
This is the most important factor to consider while choosing your dental care provider. There are very stringent sterilization protocols to be followed and it is imperative that the dentist ensures optimum compliance with all the requirements.
Dr.Smilez has stringent QC measured for sterilization. No instrument will be used without the proper sterilization in Class B autoclave. Periodic fumigation of the dental operatory and maintenance check on the sterilization equipment is done to ensure the efficiency of machinery. Our sterilization standards make Dr.Smilez one of the best dental clinics in Chennai.
3. Specialty Care
Dental procedures are highly specialized and require enormous skill sets in conjunction with the appropriate armamentarium for a successful outcome. Most mom-and-pop dental clinics in Chennai have one do-it-all dentist.
At Dr.Smilez we have a team of resident and specialist dentists. This is important, as it is not possible for a single dentist to be an expert at all treatments. There is also a team of experts monitoring the outcome for each and every treatment done.
4. Treatment plan transparency
In dentistry, there are multiple treatment options available for a given problem. In addition, there are multiple product ranges available making it a complex exercise to provide the best plan for a given situation that is also affordable to a patient. It is very easy to misrepresent a product to a layman and the patient can be completely misguided if there is no transparency. The cost of treatment can also be manipulated with differential pricing based on an individual.
Dr.Smilez is one of the few dental clinics in Chennai that provides all its patients with a choice of procedures with transparent pricing in writing, well in advance before starting the treatment, to help make an informed decision. There is also no cost escalation or major surprises once the treatment plan is accepted by our patients.
5. Patient Support
Dental treatment also requires routine maintenance. Most of the time, patients do not feel the requirement to revisit a dentist just for a review, until a new problem arises. The longevity of any dental treatment is determined by the oral hygiene maintenance of the individual.
Dr.Smilez provides to all patients complete post-operative care instructions at the end of the treatment. Regular follow up calls are given as reminders to patients to stress on the importance of maintenance. Our patient support team is available at all times to handle any queries or emergency with a separate helpline number.
6. Treatment Warranty
There are many products used in dentistry for which warranty is automatically applicable from the manufacturer. E.g., the Lifetime warranty is provided in all dental implant systems by the company that allows for a free replacement. Treatment warranty is different from product warranty which no dental clinic in Chennai will provide as there is a co-dependence on the patient for proper maintenance.
However, at Dr.Smilez, we are confident of our services, materials, techniques and follow up methods, allowing us to provide treatment warranty on dental procedures, provided the patient makes the effort to follow our strict maintenance schedule which we will ensure.
7. Electronic Patient Records
With insurance sector slowly entering the dental market, most providers make it mandatory for proper records for claims, etc. Most general dental clinics in Chennai do not maintain patient records for all patients leaving a void in the documentation of data. The best dental clinics in Chennai are equipped with software to maintain patient records and provide access to patients for their own reference.
Dr.Smilez dental clinics are powered by our own unique eSmilez hospital information system tailor-made for dental hospitals. All the treatment records, pre and post-treatment information and images are stored in the cloud. This is available for access at all times. Patients can also request their records by email which will be immediately sent to them.
8. Evidence-Based Dentistry
As mentioned earlier, the choice of materials, products, etc is multiple in dental care. The practice of all the above points should allow patients to visualize a ‘before-after’ image of the procedure done. This also helps the dentist to document and maintain patient records.
At Dr.Smilez, in addition to practising evidence-based dentistry, we also do regular treatment audits on all procedures that are done. This results in evidence-based treatment and improves treatment outcomes and ensures the longevity of dental treatment
Dr Smilez Differentiators – Why Dr.Smilez is one of the best dental clinics in Chennai
While we at Dr.Smilez enforce all the above mentioned, making it one of the best dental clinics in Chennai and Pondicherry, we are also a referral centre for international patients by association with a few clinics globally. In addition, the treatment done at Dr.Smilez is accepted as the standard of care in most dental clinics internationally. We also provide transfer of documentation for international patients and continue our aftercare services electronically
In addition, Dr.Smilez is also empanelled with almost all national and international insurance companies that provide dental coverage. We are also empanelled with government insurance of many countries and accept cashless insurance claim.
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mosmbeverlyhillsca · 8 years ago
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What are the Differences Between Prolotherapy, Stem Cell Therapy, and PRP?
Metaphors are a great way to help make sense of many ideas. In the spirit of metaphorical explanations, we at Meier Orthopedic Sports Medicine (MOSM) in Beverly Hills tried to sum up the differences among some of the pillars of regenerative medicine – stem cell therapy, platelet rich plasma (PRP), and prolotherapy.
First, we tried the Beverly Hills garden metaphor, which fit nicely for PRP, but was a stretch for stem cell therapy and prolotherapy. We also considered the general contractor approach, which, we discovered, had already been used but still had some room for improvement. So, although these pillars of regenerative medicine are so fascinating, describing them warrants a head on approach, we are going to try and give our own spin to the general contractor metaphor and broaden the scope to that of a home.
Beverly Hills orthopedic surgeon and regenerative medicine expert Dr. Steven Meier of Meier Orthopedic Sports Medicine (MOSM) informally explains how to make sense of the differences and similarities among these pillars of regenerative medicine.
Understanding the Three Main Pillars of Regenerative Medicine
Regenerative injection therapy for musculoskeletal conditions enables your body to regenerate components that keep your body functioning properly, which also typically results in a decrease of pain. Stem Cell Therapy, Platelet-Rich Plasma (PRP), and Prolotherapy are cutting-edge regenerative methods that can help address several common orthopedic conditions – arthritis, a hamstring tear, degenerative disc disease, and much more. Fortunately, access to regenerative medicine is no longer confined to professional athletes. The general public is getting in the game now – worldwide.
To find out if you are a good candidate for stem cell therapy, platelet-rich plasma (PRP), or prolotherapy, contact Meier Orthopedic Sports Medicine at 310-777-7845 to schedule a consultation. Dr. Meier and his team offer innovative regenerative medicine techniques for diverse orthopedic problems, including chronic injuries that have not improved with conventional treatments and as recovery enhancement for surgical procedures.
Your Body, Your Home
In order to better understand the difference between the three main forms of regenerative medicine therapy, think of your body as a house that is constantly receiving some sort of maintenance – workers are mowing the lawn, pulling weeds, exterminating pests, spackling cracks in the walls, fixing the plumbing, etc
 Then, one day, a load-bearing wall buckles. The plaster and drywall has worn away and the frame has buckled. In order to keep other parts of the house from being affected, you need help repairing the damage.
Regenerative Medicine Therapy – Your Construction Team
Stem Cell Therapy – The General Contractors
Stem cell therapy can be likened to sending in a team of general contractors (GC) to get the job done. Each GC has the blueprints with the information they need to get each segment of the repair job done, and each GC can redirect crew already working in nearby areas of the house to come and learn specific tasks and fix the buckled wall. The GC will pass on the blueprints to crew (nearby cells), giving them the required information to complete each job.
Stem cells use paracrine signaling to achieve this form of communication. Stem cells secrete chemical factors that are like the blueprints or instructions required to do a job. Nearby cells have surface receptors that receive the necessary blueprint information, or chemical factors. They are now equipped with the necessary programming to address the necessary task.
There are three different types of stem cells, two of which can currently be used for diverse rehabilitative purposes, and a third is enjoying its first applied success as of March 20171.
Non-Embryonic “Somatic,” or “Adult” Stem Cells are harvested from adult tissues2
Embryonic Stem Cells from (mostly) in vitro created embryos2
Induced Pluripotent Stem Cells (iPSCs) can be induced to behave as stem cells by programming them to their nascent or embryonic state2
Currently, Meier Orthopedic Sports Medicine (MOSM) utilizes adult stem cells that are harvested from the patient’s own body (autogenous).
Platelet-Rich Plasma(PR) – The Subcontractors
PRP or Platelet-Rich Plasma can be used in conjunction with stem cell  treatments to give a boost to the stem cell processes or it can be used as a stand-alone treatment. PRP acts as fuel for the stem cells. Sometimes, after a stem cell treatment at our Beverly Hills office, Dr. Meier will inject PRP at one month intervals to “recharge” the stem cells, which can remain active for 8-12 months. For PRP, the patient’s own blood is drawn and spun in a centrifuge to separate the plasma. This plasma is now concentrated with platelets and is packed with at least seven growth factors – epidermal growth factor, platelet-derived growth factor, transforming growth factor-beta, vascular endothelial growth factor (VEGF), fibroblast growth factor, insulin-like growth factor, and keratinocyte growth factor3.
PRP can be likened to subcontractors. If PRP is used as a standalone, it would be as though you pulled subcontractors who are doing other maintenance jobs in other parts of your house off their normal tasks. This amassed group of skilled workers would then focus their areas of expertise on fixing the buckled load-bearing wall. This crew wouldn’t need the blueprints from the GCs (stem cells) because they all have specific skill sets and each knows how to execute the tasks required of them. Yet, as mentioned, in the presence of stem cells (or GCs, if you will), they can still jump in and do their jobs and work together.
Prolotherapy – The Inspector
Prolotherapy can be likened to sending an irritated inspector into the space that needs attention. His irritation is sensed by the workers in other areas of the house, so they respond to the area and begin repairing the buckled wall.
The term “prolotherapy” is short for “proliferative therapy,” which involves the stimulation of a proliferative or regenerative process in the body. The prolotherapy technique involves administering multiple injections of a dextrose-saline solution in a specific concentration into or around the tissue requiring treatment. Prolotherapy can be used to treat musculoskeletal disorders in 2 main ways. One is to inject injured connective tissue structures like ligaments and tendons to induce healing. As injured or degenerated and lax supportive structures cause joint instability and painful inflammation, healing these structures reduces painful inflammation from bursitis, tendinosis or damaged cartilage.
Prolotherapy can be used to treat musculoskeletal disorders in two main ways. One is to inject injured connective tissue structures, like ligaments and tendons, in order to induce healing. Injured, degenerated or lax supporting structures cause joint instability, which can lead to painful inflammation, therefore, healing these structures leads to improved tension and reduction of joint instability, allowing the painful inflammation to subside.  way to use prolotherapy is to inject concentrated dextrose solution inside joints to reduce painful inflammation from bursitis, tendinosis or damaged cartilage.
The second way to use prolotherapy regenerative medicine is to inject a concentrated dextrose solution inside the joints to reduce painful inflammation from bursitis, tendinosis or damaged cartilage.
Prolotherapy works in several different ways. Prolotherapy has been demonstrated to induce the production of collagen. Collagen is an essential substance found in supportive ligaments, which functions like the fibers in a rope or cable. Collagen also provides the framework to support cartilage just like the rebar used in buildings.
Additionally, prolotherapy stimulates the production of glycosaminoglycans and proteoglycans, which are the building blocks of cartilage, providing its compressive and cushioning properties. Also, very importantly, dextrose prolotherapy solutions have been shown to naturally decrease neurogenic inflammation, a common source of pain in many musculoskeletal conditions.
Learn more about stem cell therapy and regenerative medicine at ScienceMag.org.
Remodeling Regenerative Medicine’s Reputation
When the discussion about using about stem cells and regenerative medicine started, controversy ensued – whether it was religious beliefs or disputes of efficacy, everyone seemed to be weighing in. While there may always be parts of new medicine that trigger controversy, regenerative medicine therapy in Beverly Hills has logged some more time and the increased volume in studies is starting to add some really good color to our deeper understanding of this exciting frontier.
To learn more about regenerative medicine and how it may benefit those suffering from orthopedic conditions, such as chronic back pain, osteoarthritis, and ligament injuries, contact Meier Orthopedic Sports Medicine at 310-777-7845 to schedule a consultation at our Beverly Hills office. Dr. Meier specializes in providing the most comprehensive and progressive treatments available, from therapeutic techniques and regenerative medicine to minimally-invasive surgery.
References:
1. http://www.sciencemag.org/news/2017/03/cutting-edge-stem-cell-therapy-proves-safe-will-it-ever-be-effective 2. https://stemcells.nih.gov/info/basics/4.htm 3. Van Pham et al. Stem Cell Research & Therapy 2013, 4:91 http://stemcellres.com/content/4/4/91
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