#kazakoff design

[brookstonalmanac]

Birthdays 4.23

Beer Birthdays

Anton Schwartz (1853)

Christian Kazakoff (1971)

Five Favorite Birthdays

Valerie Bertinelli; actor (1960)

John Oliver; comedian (1977)

Max Planck; German physicist (1858)

Sergei Prokofiev; composer (1891)

William Shakespeare; writer, playwright (1564)

Johann Adam Stamm; wagonmaker (1702)

Famous Birthdays

David Birney; actor (1939)

Shirley Temple Black; actor, ambassador (1928)

Blair Brown; actor (1949)

James Buchanan; 15th U.S. President (1791)

Steve Clark; rock musician (1960)

Cow Cow Davenport; jazz pianist (1894)

Sandra Dee; actor (1942)

Joyce DeWitt; actor (1949)

J.P. Donleavy; writer (1926)

Stephen Douglas; politician (1813)

Tony Esposito; Chicago Blackhawks G (1943)

Jim Fixx; jogger, writer (1932)

Boris Godunov; tsar of Muscovy (1598)

Virgil "Gus" Grissom; astronaut (1926)

Halston; fashion designer (1932)

Estelle Harris; actor (1936)

Art Hoppe; writer, columnist (1925)

Jaime King; model, actor (1979)

Joanna Krupa; model (1979)

Lee Majors; actor (1939)

Edwin Markham; writer (1852)

Ngaio Marsh; writer (1899)

Michael Moore; documentary filmmaker (1954)

Roy Orbison; pop singer (1936)

Kal Penn; actor (1977)

Warren Spahn; Boston/Milwaukee Braves P (1921)

J.M.W. Turner; artist (1775)

Herve Villechaize; actor (1943)

[searchsystem]

Igor Kazakov / Kazakoff Design / BSK Arkitekter / BSK 50 / Booklet / 2011

[illustratedstudy]

Sample Collection

○ Studio: Kazakoff

○ Location: Sweden

○ Client: Mira

↪

[gdbot]

Igor Kazakov / Kazakoff Design / BSK Arkitekter / BSK 50... https://ift.tt/YAC0Gl4 -> Telegram Design Bot

[viaglamour]

Just Pinned to Art Inspiration: Kazakoff Design / NordicPhotos / Programme / 2008 Launch your own makeup line. #viaGlamour https://ift.tt/32bwM6O

[cancersfakianakis1]

Cancers, Vol. 11, Pages 190: Intratumoural Heterogeneity Underlies Distinct Therapy Responses and Treatment Resistance in Glioblastoma

Cancers, Vol. 11, Pages 190: Intratumoural Heterogeneity Underlies Distinct Therapy Responses and Treatment Resistance in Glioblastoma

Cancers doi: 10.3390/cancers11020190

Authors: Akgül Patch D’Souza Mukhopadhyay Nones Kempe Kazakoff Jeffree Stringer Pearson Waddell Day

Glioblastomas are the most common and lethal neoplasms of the central nervous system. Neighbouring glioma cells maintain extreme degrees of genetic and phenotypic variation that form intratumoural heterogeneity. This genetic diversity allows the most adaptive tumour clones to develop treatment resistance, ultimately leading to disease recurrence. We aimed to model this phenomenon and test the effectiveness of several targeted therapeutic interventions to overcome therapy resistance. Heterogeneous tumour masses were first deconstructed into single tumour cells, which were expanded independently as single-cell clones. Single nucleotide polymorphism arrays, whole-genome and RNA sequencing, and CpG methylation analysis validated the unique molecular profile of each tumour clone, which displayed distinct pathologic features, including cell morphology, growth rate, and resistance to temozolomide and ionizing radiation. We also identified variable sensitivities to AURK, CDK, and EGFR inhibitors which were consistent with the heterogeneous molecular alterations that each clone harboured. These targeted therapies effectively eliminated the temozolomide- and/or irradiation-resistant clones and also parental polyclonal cells. Our findings indicate that polyclonal tumours create a dynamic environment that consists of diverse tumour elements and treatment responses. Designing targeted therapies based on a range of molecular profiles can be a more effective strategy to eradicate treatment resistance, recurrence, and metastasis.

http://bit.ly/2GrPcrl

[uncoatedletters]

Bricmate Branding for ceramic and porcelain company

Kazakoff Design has created a new arrangement for Bricmate’s catalogue, presenting the entire product range together with the various sizes and colours available. The products are displayed on a whole page with structure and colour in full scale, the opposite page providing information on size availability, article number and pricing. The cover adds three-D to the catalogue, in the form of a porcelain tile. The newly designed catalogue gives the company a competitive advantage and provides better information for the custome

[brookstonalmanac]

Birthdays 4.23

Beer Birthdays

Anton Schwartz (1853)

Christian Kazakoff (1971)

Five Favorite Birthdays

Valerie Bertinelli; actor (1960)

John Oliver; comedian (1977)

Max Planck; German physicist (1858)

Sergei Prokofiev; composer (1891)

William Shakespeare; writer, playwright (1564)

Johann Adam Stamm; wagonmaker (1702)

Famous Birthdays

David Birney; actor (1939)

Shirley Temple Black; actor, ambassador (1928)

Blair Brown; actor (1949)

James Buchanan; 15th U.S. President (1791)

Steve Clark; rock musician (1960)

Cow Cow Davenport; jazz pianist (1894)

Sandra Dee; actor (1942)

Joyce DeWitt; actor (1949)

J.P. Donleavy; writer (1926)

Stephen Douglas; politician (1813)

Tony Esposito; Chicago Blackhawks G (1943)

Jim Fixx; jogger, writer (1932)

Boris Godunov; tsar of Muscovy (1598)

Virgil "Gus" Grissom; astronaut (1926)

Halston; fashion designer (1932)

Estelle Harris; actor (1936)

Art Hoppe; writer, columnist (1925)

Jaime King; model, actor (1979)

Joanna Krupa; model (1979)

Lee Majors; actor (1939)

Edwin Markham; writer (1852)

Ngaio Marsh; writer (1899)

Michael Moore; documentary filmmaker (1954)

Roy Orbison; pop singer (1936)

Kal Penn; actor (1977)

Warren Spahn; Boston/Milwaukee Braves P (1921)

J.M.W. Turner; artist (1775)

Herve Villechaize; actor (1943)

[searchsystem]

Igor Kazakov / Kazakoff Design / Nordiskafotografer / Design Programme / 2008

[searchsystem]

Igor Kazakov / Kazakoff Design / Vostok Nafta Investment / Annual Report / 2011

[searchsystem]

Igor Kazakov / Kazakoff Design / Nordiskafotografer / Design Programme / 2008

[searchsystem]

Igor Kazakov / Kazakoff Design / Frank Review / Chris M. Forsyth – Stockholm Sub / Book / 2018

[gdbot]

Igor Kazakov / Kazakoff Design / BSK Arkitekter / BSK 50... https://ift.tt/3eXGO30 -> Telegram Design Bot

[gdbot]

Igor Kazakov / Kazakoff Design / Vostok Nafta Investment /... https://ift.tt/3e2gLXG -> Telegram Design Bot

[gdbot]

Igor Kazakov / Kazakoff Design / Frank Review / Chris M. Forsyth... https://ift.tt/3oYNUbN -> Telegram Design Bot

[gdbot]

Igor Kazakov / Kazakoff Design / Nordiskafotografer / Design... https://ift.tt/3GzwtpA -> Telegram Design Bot