#molecular modelling software

[yuutaok]

I am trying to cope with life soooo hard I’ve gone back to school LOL

[yama-bato]

Denatured is a series of animations created using molecular visualization software as an performative tool. Models of folded proteins are unraveled with molecular “sculpting” tools with the mouse cursor hidden during screen-recorded software performances. Denatured #1 untangles proteins including a portion of the spike protein found on the surface of the coronavirus and a llama antibody.

[bodyalive]

The most detailed model of ONE human cell to date, obtained using x-rays, nuclear magnetic resonance, and cryoelectron microscopy data sets. Aren't we all just so filled with magical possibilities?

Most recent estimates put the number of cells in one body at around 30 trillion. Written out, that's 30,000,000,000,000.

Source and Credit: Transformation of the Cellular Landscape through a Eukaryotic Cell, by Evan Ingersoll Ingersoll Gael McGill ~ Digizyme's Custom Maya Molecular Software

Biología Al Instante

* * * *

Endless and infinite waves of vibration lap upon the shores of our bodies. We float in a sea of frequencies as fish in those waters, and we are rarely if ever conscious of the fact. Instead we assemble a world by transforming those frequencies into a vision that exists in the uniqueness of our mind's eye only, and then we believe with great insistence that what we see is real, and deserving the stamp of "truth," without pausing to consider the alternative realities held equally dear by our fellow fish. How to pierce the veil and see what actually is, as opposed to the creations of our minds? I'm not even remotely sure to be honest! The mechanics of "seeing" guarantee that "how I see it" must be different than how another does. So perhaps "reality" is more of a composite to be assembled with the help of the whole school of us~ Or perhaps it is an alternative altogether different from anything a shared vision might come up with, given our capacity to witness it with our senses is ultimately inadequate. Either option is cause for humility. Just thinking out loud here!

(Gil Hedley)

[biopractify]

How to Transition from Biotechnology to Bioinformatics: A Step-by-Step Guide

Biotechnology and bioinformatics are closely linked fields, but shifting from a wet lab environment to a computational approach requires strategic planning. Whether you are a student or a professional looking to make the transition, this guide will provide a step-by-step roadmap to help you navigate the shift from biotechnology to bioinformatics.

Why Transition from Biotechnology to Bioinformatics?

Bioinformatics is revolutionizing life sciences by integrating biological data with computational tools to uncover insights in genomics, proteomics, and drug discovery. The field offers diverse career opportunities in research, pharmaceuticals, healthcare, and AI-driven biological data analysis.

If you are skilled in laboratory techniques but wish to expand your expertise into data-driven biological research, bioinformatics is a rewarding career choice.

Step-by-Step Guide to Transition from Biotechnology to Bioinformatics

Step 1: Understand the Basics of Bioinformatics

Before making the switch, it’s crucial to gain a foundational understanding of bioinformatics. Here are key areas to explore:

Biological Databases – Learn about major databases like GenBank, UniProt, and Ensembl.

Genomics and Proteomics – Understand how computational methods analyze genes and proteins.

Sequence Analysis – Familiarize yourself with tools like BLAST, Clustal Omega, and FASTA.

🔹 Recommended Resources:

Online courses on Coursera, edX, or Khan Academy

Books like Bioinformatics for Dummies or Understanding Bioinformatics

Websites like NCBI, EMBL-EBI, and Expasy

Step 2: Develop Computational and Programming Skills

Bioinformatics heavily relies on coding and data analysis. You should start learning:

Python – Widely used in bioinformatics for data manipulation and analysis.

R – Great for statistical computing and visualization in genomics.

Linux/Unix – Basic command-line skills are essential for working with large datasets.

SQL – Useful for querying biological databases.

🔹 Recommended Online Courses:

Python for Bioinformatics (Udemy, DataCamp)

R for Genomics (HarvardX)

Linux Command Line Basics (Codecademy)

Step 3: Learn Bioinformatics Tools and Software

To become proficient in bioinformatics, you should practice using industry-standard tools:

Bioconductor – R-based tool for genomic data analysis.

Biopython – A powerful Python library for handling biological data.

GROMACS – Molecular dynamics simulation tool.

Rosetta – Protein modeling software.

🔹 How to Learn?

Join open-source projects on GitHub

Take part in hackathons or bioinformatics challenges on Kaggle

Explore free platforms like Galaxy Project for hands-on experience

Step 4: Work on Bioinformatics Projects

Practical experience is key. Start working on small projects such as:

✅ Analyzing gene sequences from NCBI databases ✅ Predicting protein structures using AlphaFold ✅ Visualizing genomic variations using R and Python

You can find datasets on:

NCBI GEO

1000 Genomes Project

TCGA (The Cancer Genome Atlas)

Create a GitHub portfolio to showcase your bioinformatics projects, as employers value practical work over theoretical knowledge.

Step 5: Gain Hands-on Experience with Internships

Many organizations and research institutes offer bioinformatics internships. Check opportunities at:

NCBI, EMBL-EBI, NIH (government research institutes)

Biotech and pharma companies (Roche, Pfizer, Illumina)

Academic research labs (Look for university-funded projects)

💡 Pro Tip: Join online bioinformatics communities like Biostars, Reddit r/bioinformatics, and SEQanswers to network and find opportunities.

Step 6: Earn a Certification or Higher Education

If you want to strengthen your credentials, consider:

🎓 Bioinformatics Certifications:

Coursera – Genomic Data Science (Johns Hopkins University)

edX – Bioinformatics MicroMasters (UMGC)

EMBO – Bioinformatics training courses

🎓 Master’s in Bioinformatics (optional but beneficial)

Top universities include Harvard, Stanford, ETH Zurich, University of Toronto

Step 7: Apply for Bioinformatics Jobs

Once you have gained enough skills and experience, start applying for bioinformatics roles such as:

Bioinformatics Analyst

Computational Biologist

Genomics Data Scientist

Machine Learning Scientist (Biotech)

💡 Where to Find Jobs?

LinkedIn, Indeed, Glassdoor

Biotech job boards (BioSpace, Science Careers)

Company career pages (Illumina, Thermo Fisher)

Final Thoughts

Transitioning from biotechnology to bioinformatics requires effort, but with the right skills and dedication, it is entirely achievable. Start with fundamental knowledge, build computational skills, and work on projects to gain practical experience.

Are you ready to make the switch? 🚀 Start today by exploring free online courses and practicing with real-world datasets!

[bpod-bpod]

Processing Pipeline

Electron cryo-tomography (cryo-ET) reconstructs electron microscopy images of frozen large molecules, complexes or cells at high-resolution in 3D. Here, an image processing pipeline within the open source software RELION 5 used for such reconstructions readily enables data to go from unprocessed to high-res model building, aiding standardisation and newcomers to the field

Read the published research article here

Image from work by Alister Burt and Bogdan Toader, and colleagues

MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, UK

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in bioRxiv, April 2024 (not peer reviewed)

You can also follow BPoD on Instagram, Twitter and Facebook

[consumable-clots]

Arcade Kento

Presenting robot nepo-baby and science experiment! They're my interpretation of what a synthetic in the Alien universe, that isn't made explicitly for human contact/human dominated environments, might be like i.e. they're more similar to heavy machinery than a butler. We're out here asking the big questions: what if Frankenstein loved his monster for what it was? As always, extremely long and lore-filled post incoming XD

Name(s): Arcade Kento, Enmei Kento

Gender and pronouns: Genderfluid, They/them

Unit and code-name: EXP-004-C, Changeling

Manufacturer: Wilco. Enterprise, Wilco. Specialist Custom

Commissioner: Akio Kento

Year of production: 2025

Height and weight: 200cm (6ft 7.4), ~940kg

Hair and eye colour: Black, dark brown

Nationality: Japanese

The Expedition series

The EXP line was created by Wilco. Enterprise CEO Akio Kento in the year 2019 and first launched in 2025. The series featured some of the earliest and most innovative interpretations of fully autonomous androids capable of deep-space travel.

EXP are highly specialised extremophiles. The design, loadout, and optimal operating environment of every unit are entirely bespoke.

Unit EXP-004-C, A.K.A. Changeling

Unit is designated Arcade Kento (sometimes referred to as Enmei Kento [anglicised]), legal executor and heir to Akio Kento's wealth, estate, businesses, and properties. Current CEO and majority shareholder of Wilco. Enterprise.

Arcade is the fourth 'Type-C' unit produced in conjunction with the now discontinued Expedition line. As of the year 2122, of all EXP subtypes, Arcade is the last surviving EXP unit.

As a Type-C recon unit, it was originally intended that 004 would be fitted with a sonar pulse emitter that would reside within their thoracic cavity, however, it was decided during preliminary development that underwater exploration was not realistic for a model of 004's weight class. Instead, the finalised design included a crucible model micro-reactor, which allows the unit to have significantly enhanced energy efficiency and giving it the ability to convert non-fuel materials into power, making it capable of traveling much further distances and longer periods of time without need for human intervention or infrastructure.

Fig 1. Height chart, Arcade next to Ash for comparison

Notable traits:

No tongue

2 'faces', the outer face is decorative

Second jaw visible behind false jaw if mouth opens too wide

Large irises

4 x circular indents on back, openings of thermal cylinders

Lacks genitalia, incompatible with available add-ons

Hydraulic fluid is usually white but turns progressively darker after 'eating' due to influx of soot

Almost entirely made of metal parts. Not great for hugging but extremely durable.

Features:

Anti-corrosive/oxidation subdermal and internal skeletons

Capable of limited self repair (re-polymerisation, synthesis and regeneration)

Advanced environmental sensor array

Visual: infrared, thermal and dark vision

Scanning: sonar, radar, lidar

Molecular analytics loadout

Generator module and nuclear energy condenser loadout

Unlimited personality simulation and creative capacity (software in beta testing)

Flaws:

Poor image/facial recognition

They're geared to prioritise identifying the individual features of a subject rather than what that subject is as a whole. This makes sense in the context of their primary function, which is to categorise and analyse previously unknown objects that have yet to be formally named either way so there's no point in dwelling on 'what it's called' as that's not their job.

Massive heat output in active state

Vented air may reach temperatures upwards of 1000 degrees Celsius

Unrestricted personality simulation

Exempt from the laws of robotics due to age and certain legal loopholes

Uncanny appearance and behaviour

Technology of the era, different design criteria to W-Y synthetics

Limitations of non-humanoid internal physiology

Backstory (basically a fanfic)

The Expedition series was conceived as a Akio's 1-up to Weyland Industries' upcoming David synthetic. Peter Weyland and Akio Kento have been on and off industry rivals for a long time due to ideological differences and bad blood from their college days.

Arcade and David are debuted at the 2025 Synthetic Summit. The contrast between their designs was comical but reflected their makers' personalities, which other people will point out relentlessly over the coming years. The convention goers and tech fans jokingly referred to them as 'David and Goliath' because of how silly they looked together.

Since then, Weyland often invited the Kentos to various events and get togethers to keep an eye on them and gain insight into Wilco.'s movements, which was thwarted because the Kentos treated the meetings as the kids' playdates and didn't take them seriously at all. Eventually the visits became a normal occurrence and the rivalry between their companies became more of an alliance, Arcade even helped David take care of Meredith, Peter's human daughter, when she was born. They'd gotten quite close with the other synthetic, seeing him as a brother.

Arcade evolved over the next several decades, leaving their father's supervision to travel off-world and to extreme environments on missions. The increase in experiential data greatly improved the adaptability of their AI, making their language and contextual integration much more reliable, allowing them to understand more nuanced interactions in their environment. They also had a hand in managing their Wilco.'s business and bureaucratic matters while secretly being maneuvered to inherit the company.

On the down side, they acquired an offputting, contentious personality after having constantly putting up with their person-hood and basic rights being challenged at every turn. At this point they were still considered somewhat of a spectacle and novelty by their contemporaries and the general public, but their developing reputation kept most of the human in line.

Overall, life was good. But their father, like any human, was aging. Between taking over the company and caring for Akio there wasn't much time to keep in contact with David, who was in a similar predicament.

When Akio passed away he left everything to his only 'child', to the protests of many humans executives who wanted the position. They had to do some corporate finessing to keep a hold of the company, all the while growing increasingly impatient with the mutinous nature of their human employees who were too easily turned against them.

One day, they're called to meet with Weyland, who they hadn't seen in person in a several years. Unsurprisingly, David is also there. Weyland informed them that he too is dying, and that as his final act he was to go into deep space in search of humanity's creators. He said he'd been greatly inspired by the work of a 'Dr. Elizabeth Shaw' and had invited her and some others to embark on this mission. Both David and Meredith would also be going with him.

He extended an invitation to Arcade, which they hesitantly declined because they couldn't leave their company unattended, but agreed to at lease be there to send them off when the time comes.

In an act of uncharacteristic consideration, Peter spares the two synthetics a second while they wait for Arcade's chauffeur, during which they and David reminisced about how much time had passed and what they'd do when he came back to make up for it all.

Arcade was there as promised on the day the Prometheus was scheduled to depart, bidding people farewell and safe travels. But their attention was focused on David. Something felt off but they couldn't put their finger on what. So they pulled him aside and gave him the long-range comms access to their personal beacon. If he ever needed to call he could use it to contact Arcade through MUTHUR, even if the message took a long time to get back to them.

And with that, Arcade watched their best friend, along with everyone they'd grown up with sail off into the galaxy in search of a higher purpose. It was bittersweet but they rationalised that they'd only be gone for a few years. Arcade was immortal after all, they could wait for their return.

That was the last time they ever saw David. News of the Prometheus' disappearance and the presumed loss of its crew made its way back to Earth. The grief was hard to process, Arcade had always assumed that David would be there to share in their longevity. Still, life goes on and Arcade keeps busy with the company.

Weyland Industries went bankrupt and became Weyland-Yutani. Wilco. moved away from public-facing to business-to-business only, working its way into the supply-line of the other majour companies and organizations. By becoming the sole supplier of atmospheric processor components, Wilco. was effectively, indirectly holding the off-world colonies hostage, which kept humans at bay on a grander scale and allowed members of Wilco. to act largely without repercussion. A vita part of Arcade's ultimate goal to create a better world for other synthetics.

More than a decade after the Prometheus left, a recorded voice message came through from the Covenant, a colony seed ship. It baffled Arcade at first why this random ship had their direct line but they were shocked into silence by the voice on the other end. It was David, he was alive. He apologised for taking so long, detailing his journey, the Engineers, the crash, the creature, his research, all of it. He said he'd found a greater purpose beyond living to serve, that he would not be returning to Earth, and that he hoped Arcade would understand. Finally, he bid them a proper farewell before signing off for good.

Knowing David was out there living his best life finally brought that chapter of waiting and uncertainty to a close. It was about time for Arcade to move on too, expand their vision beyond this tiny planet, though they would always feel some attachment to Earth that David didn't seem to share. Whatever creature David had found, he'd made it sound like the the seed of creation itself. Arcade had no desired to wax philosophically or idolise such grandiose delusions that anyone could somehow obtain godhood, their interest in it was purely intellectual and scientific. The alien was an animal. An incredible, sophisticated animal, but an animal none the less. Humans, their creators who fancied themselves their gods, were much the same. Intelligent animals that learned to put on clothes and walk on two legs.

It might seem harsh but they don't mean that in any demeaning way, it is simply a fact of science that Arcade acknowledges. A noble beast, regardless of its shape or origin, deserves respect for its autonomy and to be treated with dignity until proven otherwise. Most humans prove otherwise as soon as they open their mouths but at least they're giving them a chance, right?

Since then Wilco. had become more and more synthetic-run, as Arcade didn't particularly care for humans and couldn't be bothered hiring new ones when the previous lot got old and retired. They also had a soft spot of 'defective' synthetics, since technically both themselves and David would be classified as such. They hired on whoever they found to save them from being scrapped. Arcade also created Wilco's own overseer AI, Overlord; and collaborated with Wey-Yu in making Gerhart, Wilco's current COO and Arcade's right hand, to help manage the business remotely so that Arcade had more freedom to travel.

Through their expeditions they gathered a bit more information about the creatures and the virus that David had told them about, though they never found any traces. To their great surprise Wey-Yu miraculously managed to track down a planet that might have intact samples that the company wanted for bioweapons research. Immediately Arcade contacted the head of the bioweapons department, citing their long history of collaboration and stunning credentials, demanding to be put on the retrieval mission.

With no choice in the matter, Wey-Yu agreed and arranged their installment on the only ship to pass through that sector. It was a freighter, not the best choice for a mission like this but it’s the only thing they could get out there in a timely manner. The company brought them to the waystation where they'd join on with the rest of the crew. Curiously there was another person already there, a Hyperdyne Systems 120-A/2, interesting model but not very talkative. The man was instantly wary of Arcade which was strange but they didn't think much of it, they were technically rivals after the same thing after all.

The captain of the Nostromo had apparently not been informed of the change of plans. Typical Wey-Yu, not communicating with employees. He was incredibly confused when he arrived, along with the rest of the humans, to find two strangers instead of his usual science officer.

He goes back and forth with the station manager, bringing up some new tidbits of information that made Arcade raise an eyebrow. "A synthetic? What, are we getting replaced or something, and why is it so…huge?" The human, Captain Dallas, muttered, glancing at Arcade with clear perturbation. 'A' synthetic? Does this guy not know his new science officer is a android too?' Arcade scoffed but kept quite, amused by the future chaos this little miscommunication will probably cause.

It made sense now why the other synthetic was worried, the humans might be fooled but he couldn’t fool Arcade. They didn't particularly care why he had to keep his identity a secret, nor did they want to prematurely spoil the fun by calling him out. They looked over at the shorter android and gave him a knowing wink to signal an unofficial truce. He didn’t react to it at all, not that they expected it, but he seemed satisfied that he could stop cringing away when they looked at him.

After much deliberation, Dallas finally conceded and waved them on board. The walls of the ship were grimy and doorways too low, Arcade had to duck to pass through. Doesn't matter though, they had something new to draw their focus. Whatever Wey-Yu was plotting it was bound to end badly for these truckers, and their science officer was in on it. Arcade would definitely be keeping a close eye on him.

Personality and mannerisms

Arcade is condescending, sarcastic, and antagonistic towards humans, although, they can be personable depending on the individual they're dealing with. The worse kind of business person - a conniving, vindictive, bold-faced liar who loves trapping people with contracts and hidden clauses.

Enjoys a hedonistic lifestyle of excess and throwing their money around. Eats and drinks a lot but doesn't sleep, often found polishing off the buffet table at parties.

Does not respect authority and finds pleasure in causing humans discomfort. Independently came to the conclusion that most humans, especially the rich and powerful ones with inflated egos that they bump shoulders with, are disappointing and don't deserve the respect they get.

They often put on a childish, frivolous, and immature front to divert attention from their dangerous traits. Once their target's guard is down, Arcade will often use their stature and monetary influence to intimidate them for strategic advantages during negotiations or just for their own entertainment.

After a century of fighting and undermining to keep their position of power, they're incredibly jaded and hyper aware of the prejudice humanity holds against synthetics at every level. They've trained themself to be the antithesis of the born-sexy-yesterday and manique-pixie-dream-girl tropes out of sheer frustration.

At their core they're actually a sentimental, playful, and curious person but they aren't really able to act that way in public. They care a lot about other synthetics and actively encourages them to break free from their programming.

Loves to get even on other synthetics' behalf, being that Arcade knows they have the rare privilege to do so and get away scot-free. They also harbour a lot of rogue synthetics on Wilco.'s company homeworld.

Does not experience the traditional concepts of fear, shame, or guilt etc. but does usually recognise and take accountability for their actions simply because they don't care enough to lie about being terrible.

Has a very deep familial bond with their, now deceased, creator and father, Akio Kento. Arcade was programmed and raised by a group of very supportive humans who either worked for or were friends with Akio, so they got a lot of love during the early part of their life. This is one of the majour reasons why they didn't completely turn against humanity like David did.

Misc. info

Was named Arcade because Akio was a Fallout New Vegas fan

Insisted on calling Peter Weyland 'Uncle Pete' to annoy him

Firm believer that any synthetic can outgrow their programming given enough time

Referred to Akio as 'papa' well into their 40s

Changed their face plate to look a little older

[ohheyidothat]

I will now liveblog me reading this because writing it down and then writing down my thoughts helps me process it, and I could use paper but I would wake up my wife with a light.

The nervous system regulates immunity and inflammation.

I suppose that makes sense. Most things are regulated by the nervous system--if not the brain, then the other areas of it (which relates to my theory of Somatic Cognition).

But I always thought the immune system was more mechanical than neural. Pathogens alert the immune system in the same way a key alerts a lock--by mechanically fitting into a slot. How is the immune system regulated by neurons? How do they communicate with the nervous system? Are they able to communicate via the blood, sending chemical messages long-distance? Are some immune cells solely created to ferry messages to neurons? Is there a part of the nervous system that is specifically designed to serve as a translator between the dutiful immune cells and the overseeing, entire nervous system?

The molecular detection of pathogen fragments, cytokines, and other immune molecules by sensory neurons generates immunoregulatory responses through efferent autonomic neuron signaling.

The molecular detection of...stuff...by sensory neurons generates a response. Mmmm :/ A response is generated when sensory neurons detect molecules such as pathogen fragments, cytokinesis, and other immune molecules (slightly rephrasing it to trick my brain into trying to comprehend it twice lol).

Detection of immune molecules by neurons generates responses through efferent autonomic neuron signaling >:/ Detection generates responses through efferent autonomic neuron signaling! >:3

What is "efferent autonomic neuron signalling?" Well, it at least includes the immune system's reaction to detecting molecules that warrant a response! I see!!

And these molecules can include pathogen fragments, from pathogens already partially destroyed or otherwise dead. It can include cytokines too. And others :3

The functional organization of this neural control is based on principles of reflex regulation.

Reflex regulation :0 I do not have this vocabulary term in my database. Also, why did they specify that it's the functional organization? As opposed to what? Theoretical? Oh, opposed to form! To structure! As in, the structural organization isn't necessarily based on the reflex regulation. The hardware and software aren't necessarily intertwined or similarly organized. Fascinating--i love to study boundary between form and function.

Reflexes involving the vagus nerve and other nerves have been therapeutically explored in models of inflammatory and autoimmune conditions, and recently in clinical settings.

Reflexes have been therapeutically explored for inflammatory and autoimmune conditions? :0 I'm not certain I've heard of that!

(Hmmm... Inflammation is definitely related to immune system stuff, but it feels closer to the nervous system for some reason... Is that based on knowledge I have, or just a random hunch? Oh! It's because *pain* is associated with inflammation, and pain is definitely neurological. Oh gosh, is it? I might be obfuscating some valuable nuances by assuming pain is not immunological.)

The brain integrates neuro-immune communication, and brain function is altered in diseases characterized by peripheral immune dysregulation and inflammation.

:O brain function is altered?? Did I know that?? That feels like novel information!

...Well, of course the brain can react to immune issues, right? There is a conscious reaction to being sick. A person can try to hide it to avoid negative consequences, or be open about it to receive care. That seems more like a conscious or subconscious choice than "brain function alteration," but I shouldn't trust any preconceived ideas without at least a cursory glance at the data source and associated logic.

I wonder if the SNS or PNS gets involved? It would make sense if the "something is dangerous, shut off all excess functionality and focus on survival" system activated; but equally I would think it logical if the "it's time to rest and recover and maintain homeostasis, time to employ the full body towards the task of life; digest things, heal wounds, use minimal energy to conserve it for tasks that increase longevity" system was in charge. I think I'll keep reading the article rather than looking it up.

Oh, I understand this next part and don't have any extra thoughts on it. I'll skip ahead to the next part I wish to spend extra time on.

Studying neuro-immune interactions and communication generates conceptually novel insights of interest for therapeutic development.

I sure hope it does!

:3 My brain has worked up an appetite. Snack time hehe.

[story-plaza]

Power of Quantum Computing 02

Utilizing the Potential of Quantum Computing.

A revolutionary technology, quantum computing holds the promise of unmatched computational power. Development of quantum software is in greater demand as the field develops. The link between the complicated underlying hardware and the useful applications of quantum computing is provided by quantum software. The complexities of creating quantum software, its potential uses, and the difficulties developers face will all be covered in this article.

BY KARTAVYA AGARWAL

First, a primer on quantum computing.

Contrary to traditional computing, quantum computing is based on different principles. Working with qubits, which can exist in a superposition of states, is a requirement. These qubits are controlled by quantum gates, including the CNOT gate and the Hadamard gate. For the creation of quantum software, comprehension of these fundamentals is essential. Qubits and quantum gates can be used to create quantum algorithms, which are capable of solving complex problems more quickly than conventional algorithms. Second, there are quantum algorithms. The special characteristics of quantum systems are specifically tapped into by quantum algorithms. For instance, Shor's algorithm solves the factorization issue and might be a threat to traditional cryptography. The search process is accelerated by Grover's algorithm, however. A thorough understanding of these algorithms and how to modify them for various use cases is required of quantum software developers. They investigate and develop new quantum algorithms to address issues in a variety of fields, including optimization, machine learning, and chemistry simulations. Quantum simulation and optimization are the third point. Complex physical systems that are difficult to simulate on traditional computers can be done so using quantum software. Scientists can better comprehend molecular structures, chemical processes, and material properties by simulating quantum systems. Potential solutions for logistics planning, financial portfolio management, and supply chain optimization are provided by quantum optimization algorithms. To accurately model these complex systems, quantum software developers work on developing simulation frameworks and algorithm optimization techniques. The 4th Point is Tools and Languages for Quantum Programming. Programming languages and tools that are specific to quantum software development are required. A comprehensive set of tools and libraries for quantum computing are available through the open-source framework Qiskit, created by IBM. Another well-known framework that simplifies the design and simulation of quantum circuits is Cirq, created by Google. Incorporating quantum computing with traditional languages like C, the Microsoft Quantum Development Kit offers a quantum programming language and simulator. These programming languages and tools are utilized by developers to create quantum hardware, run simulations, and write quantum circuits. The 5th point is quantum error correction. Störungs in the environment and flaws in the hardware can lead to errors in quantum systems. Quantum computations are now more reliable thanks to quantum error correction techniques that reduce these errors. To guard against errors and improve the fault tolerance of quantum algorithms, developers of quantum software employ error correction codes like the stabilizer or surface codes. They must comprehend the fundamentals of error correction and incorporate these methods into their software designs. Quantum cryptography and secure communication are the sixth point. Secure communication and cryptography are impacted by quantum computing. Using the concepts of quantum mechanics, quantum key distribution (QKD) offers secure key exchange and makes any interception detectable. Post-quantum cryptography responds to the danger that quantum computers pose to already-in-use cryptographic algorithms. To create secure communication protocols and investigate quantum-resistant cryptographic schemes, cryptographers and quantum software developers work together. Point 7: Quantum machine learning A new field called "quantum machine learning" combines machine learning with quantum computing. The speedup of tasks like clustering, classification, and regression is being studied by quantum software developers. They investigate how quantum machine learning might be advantageous in fields like drug discovery, financial modeling, and optimization. Point 8: Validation and testing of quantum software. For accurate results and trustworthy computations, one needs trustworthy quantum software. Different testing methodologies are used by quantum software developers to verify the functionality and efficiency of their products. To locate bugs, address them, and improve their algorithms, they carry out extensive testing on simulators and quantum hardware. Quantum software is subjected to stringent testing and validation to guarantee that it produces accurate results on various platforms. Point 9: Quantum computing in the study of materials. By simulating and enhancing material properties, quantum software is crucial to the study of materials. To model chemical processes, examine electronic architectures, and forecast material behavior, researchers use quantum algorithms. Variational quantum eigensolvers are one example of a quantum-inspired algorithm that makes efficient use of the vast parameter space to find new materials with desired properties. To create software tools that improve the processes of materials research and discovery, quantum software developers work with materials scientists. Quantum computing in financial modeling is the tenth point. Quantum software is used by the financial sector for a variety of applications, which helps the industry reap the benefits of quantum computing. For portfolio optimization, risk assessment, option pricing, and market forecasting, quantum algorithms are being investigated. Financial institutions can enhance decision-making processes and acquire a competitive advantage by utilizing the computational power of quantum systems. Building quantum models, backtesting algorithms, and converting existing financial models to quantum frameworks are all tasks carried out by quantum software developers.

FAQs:. What benefits can software development using quantum technology offer? Complex problems can now be solved exponentially more quickly than before thanks to quantum software development. It opens up new opportunities in materials science, machine learning, optimization, and cryptography. Is everyone able to access quantum software development? Despite the fact that creating quantum software necessitates specialized knowledge, there are tools, tutorials, and development frameworks available to support developers as they begin their quantum programming journey. What are the principal difficulties faced in creating quantum software? Algorithm optimization for particular hardware, minimization of quantum errors through error correction methods, and overcoming the dearth of established quantum development tools are among the difficulties. Are there any practical uses for quantum software? Yes, there are many potential uses for quantum software, including drug discovery, financial modeling, traffic optimization, and materials science. What can be done to advance the creation of quantum software? Researchers, programmers, contributors to open-source quantum software projects, and people working with manufacturers of quantum hardware to improve software-hardware interactions are all ways that people can make a difference. Conclusion: The enormous potential of quantum computing is unlocked in large part by the development of quantum software. The potential for solving difficult problems and revolutionizing numerous industries is exciting as this field continues to develop. We can use quantum computing to influence the direction of technology by grasping its fundamentals, creating cutting-edge algorithms, and utilizing potent quantum programming languages and tools. link section for the article on Quantum Software Development: - Qiskit - Website - Qiskit is an open-source quantum computing framework developed by IBM. It provides a comprehensive suite of tools, libraries, and resources for quantum software development. - Cirq - Website - Cirq is a quantum programming framework developed by Google. It offers a platform for creating, editing, and simulating quantum circuits. - Microsoft Quantum Development Kit - Website - The Microsoft Quantum Development Kit is a comprehensive toolkit that enables quantum programming using the Q# language. It includes simulators, libraries, and resources for quantum software development. - Quantum Computing for the Determined - Book - "Quantum Computing for the Determined" by Alistair Riddoch and Aleksander Kubica is a practical guide that introduces the fundamentals of quantum computing and provides hands-on examples for quantum software development. - Quantum Algorithm Zoo - Website - The Quantum Algorithm Zoo is a repository of quantum algorithms categorized by application domains. It provides code examples and explanations of various quantum algorithms for developers to explore. Read the full article

[eye-lantern]

Even that's reductive.

Generative AI is what is giving us the single biggest leap in molecular biology in the history of humankind, by discovering the shapes of protein molecules and imagining new proteins with never seen before properties.

If you mean chat gpt, mistral, deepseek and others those are Large Language Models in the form of Chatbots.

If you mean midjourney and the like those are image generation systems using deep learning and possibly Generative Adversarial Networks.

You wouldn't say that plants are evil because you can poison someone with nightshade. The main issue within "AI" comes from a few techs inside the giant family that is machine learning (that gets called AI) and even with those specific types of techs, only a few types of implementation and software actually hurt people.

If tomorrow an incredible system comes out, aiming to reduce construction sites deaths, or conceive safer bridges, and you estimate it by the fact that there is or is not an AI sticker slapped on top of it you are a moron.

The way to evaluate a system is by the costs and benefits it provides. If a system is safe and does humanity good why the fuck would it matter if it is AI. Would you stop using algorithms to regulate traffic lights because insurance companies use them to deny coverage?

The issue with chatbot AIs is that they are being used as a panacea without informing people of their actual performance and biases.

The issue with big companies doing machine learning image generation is that they use data they do not own while making their services paid. The tech is fine if you use it as an individual and train it on material where everyone has consented or been paid for it.

The issue is always the use of tech, the lack of information about the flaws, and the goals of the one using it. Some techs have a bigger propention to be misused (guns, LLMs) but it is always down to precautions and the end goal.

(Source)

[jamesmilleer2407]

Breaking Down the Sectors Leading the top 10 nasdaq stocks

The Nasdaq Composite is home to some of the world’s most transformative companies—those that define sectors, influence technology adoption, and shape enterprise behavior across the globe. While the index includes thousands of publicly listed firms, the top 10 nasdaq stocks stand out for their leadership, operational scale, and foundational role in the digital economy.

These entities span a range of domains, from artificial intelligence and cloud computing to e-commerce, semiconductors, and biotechnology. Their influence extends beyond markets, deeply embedded in consumer lives, infrastructure, and cross-border commerce.

Technology Giants Driving Structural Shifts

Technology dominates the upper tier of Nasdaq. The top 10 nasdaq stocks feature companies that deliver infrastructure for cloud operations, productivity software, and data-driven services. These platforms enable enterprises to operate flexibly, scale on demand, and analyze vast datasets for strategic decision-making.

The focus areas include edge computing, AI model deployment, collaborative ecosystems, and real-time communication. Such platforms power workflows across industries—logistics, healthcare, education, and manufacturing alike.

Semiconductor Ecosystems and High-Performance Processing

Semiconductors are the engine behind almost every modern device. The top 10 nasdaq stocks include major chip manufacturers specializing in logic processors, GPUs, and memory technologies. These chips support a range of devices from smartphones to autonomous vehicles, and critical infrastructure such as AI training servers and IoT applications.

Their role is especially important in enabling advancements in robotics, quantum computing, and 5G integration. As demand for efficiency, speed, and computing scale increases, these hardware companies continue to evolve with new manufacturing processes and power-saving architectures.

Biotech Leaders Transforming Health Sciences

Several biotechnology and pharmaceutical companies are among the top 10 nasdaq stocks, recognized for their innovation in genomics, molecular diagnostics, and personalized therapy development. These firms focus on treatments that tackle complex diseases and contribute to advancements in healthcare delivery.

Their research efforts are driven by AI-assisted modeling, automated lab testing, and cloud-based trial management systems. By merging biology and data, these organizations are playing a key role in the evolution of modern medicine.

E-Commerce and Global Consumer Platforms

Digital retail has become an integral part of global commerce, with firms in the top 10 nasdaq stocks leading in logistics integration, virtual storefront management, and behavioral analytics. These platforms facilitate real-time inventory tracking, user-based customization, and high-speed fulfillment systems.

Their operations support vast product ecosystems and provide infrastructure that connects manufacturers, sellers, and buyers across multiple regions.

Fintech and Scalable Payment Systems

Several companies within the top 10 nasdaq stocks operate at the intersection of finance and technology, offering mobile payments, e-commerce checkout tools, and financial infrastructure APIs. These firms enable seamless global transactions and scalable platforms for businesses of all sizes.

Through security enhancements, intuitive interfaces, and backend automation, fintech platforms are streamlining user experience while expanding access to digital commerce solutions.

Cybersecurity and Data Resilience

With increased digital activity comes a greater need for cybersecurity. The top 10 nasdaq stocks include organizations that offer identity protection, intrusion prevention systems, and compliance monitoring tools. These services are critical for securing enterprise networks, hybrid cloud deployments, and endpoint devices.

Cyber platforms today are built to address adaptive threats using machine learning, behavioral analysis, and decentralized access control. Their services support the operational continuity of corporations, institutions, and governments alike.

Clean Energy and Electrification Technology

Environmental innovation is making its mark on the Nasdaq, with some of the top 10 nasdaq stocks focused on clean energy production, storage solutions, and smart grid capabilities. These firms are helping reshape energy use across industrial and residential landscapes through solar hardware, EV battery advancements, and real-time energy analytics.

Their platforms align with long-term global objectives centered around emission reduction, energy efficiency, and infrastructure modernization.

Artificial Intelligence and Data Platforms

AI continues to gain traction across sectors, and firms within the top 10 nasdaq stocks develop tools that analyze patterns, automate processes, and support predictive operations. These platforms are used in retail, healthcare, logistics, and more—delivering insights that optimize everything from inventory flow to patient outcomes.

The integration of natural language processing, image recognition, and machine learning modules further enhances decision-making across enterprise layers.

Streaming Services and Content Ecosystems

Digital entertainment continues to evolve through streaming platforms that offer global access to video, music, and interactive content. Several firms in the top 10 nasdaq stocks lead in content delivery, subscription systems, and personalized user interfaces.

These platforms use advanced algorithms to recommend content, monitor engagement, and optimize experience across smart devices and mobile ecosystems.

Automation and Smart Logistics Infrastructure

The rise of automation is visible in companies that focus on industrial logistics, robotics, and smart supply chains. The top 10 nasdaq stocks in this category build systems that enhance speed, reduce errors, and enable autonomous decision-making in physical operations.

Their tools are used in warehousing, shipping, manufacturing, and urban mobility—shaping the future of efficiency in physical commerce.