#pod5

[felixcloud6288]

My professor asked me to do some digging into how a certain program processes data from a file type called pod5. pod5 is a proprietary file format for Oxford Nanopore reads. Since the files are completely illegible to humans, most papers related to nanopore research don't include the original pod5 files and instead have the human readable translations. It took me five days to find a single pod5 file.

[avatarthelegbender]

6/12 POD 5: Summary

- range is way easier into flexion after biking for a bit

- maybe 0-100deg?

- pain still minimal, only hurts when ranging

- finally starting to ice more like I should. The ice knee sleeve fits now

- def feeling how the day to day can be frustrating cause it seems like it’s a daily repeated struggle of trying to get more flx and then back into terminal knee ext with minimal to no noticeable change BUT technically took two days off of self-PT cause of the travel weekend. Only ranged it about 3 times each day

- NMES def helps to get my quad activation started. Then I turn it off to try and do it more on my own. Finally saw some improvement in SLR compared POD 1-4 with the NMES and mass practice. But nothing compared to what I was getting POD 0

- check out that sunburn

[alfredoszinis]

https://www.pond5.com/item/118976981

[mvppskorea]

#revisionsurgeryexpert #revisionsurgerykorea #eye #nose #pod5(MVP Plastic Surgery Korea에서) https://www.instagram.com/p/BniVh_AnJmH/?igshid=1rtpa3ugsy0kb

[itswallstreetpr]

Why Crypto Stocks May be the Best Route to Monetizing the Bitcoin Bear (SDIG, BLQC, HUT, MARA, MSTR, RIOT, COIN, SQ)

Bitcoin has been in another major bear market over recent months (1). But, as any experienced investor knows, bear markets and bull markets come and go. Just take a gander at a long-term chart for Crude Oil or Gold or Copper or the Euro. Bitcoin is not a stock. It's closer to a commodity or a currency market (2). And history is replete with evidence that foreign exchange markets and major commodities don't move in one direction forever. They ebb and flow. Hence, while we are somewhere in the process of an "ebb" in bitcoin and the broad cryptocurrency complex, this too shall pass. The big question for investors is about how to best use the opportunity of this bear to position for maximum advantage ahead of the next bull cycle. The seeds of that cycle are being planted now. In time, they will flower and bear fruit. Crypto-related stocks could be one of the best implementation strategies to take advantage of the opportunity in play now because many have seen declines even greater than Bitcoin, yet some are positioned to weather the storm better than others, even though the selling in the space has been indiscriminate. With that in mind, we take a look below at some of the most interesting crypto-related stock stories in the space.   Stronghold Digital Mining Inc. (Nasdaq:SDIG) engages in crypto asset mining. It wholly-owns and operates Scubgrass Plant, an environmentally beneficial coal refuse power generation facility. Stronghold is a vertically integrated Bitcoin mining company with an emphasis on environmentally beneficial operations. Stronghold houses its miners at its wholly owned and operated Scrubgrass Plant and Panther Creek Plant, both of which are low-cost, environmentally beneficial coal refuse power generation facilities in Pennsylvania. Stronghold Digital Mining Inc. (Nasdaq:SDIG) recently reported financial results for its first quarter ended March 31, 2022, and provided an operational update, including news that the company mined 438 Bitcoin during the first quarter of 2022, including 198 in March 2022 and mined over 100 Bitcoin in first 13 days of May with average hash rate of 0.9 exahash per second (“EH/s”) in the first quarter of 2022. “Since we reported FY 2021 earnings on March 29, 2022, we believe that we have made significant progress on enhancing our operations, and we are executing on our goal of exceeding 4 EH/s by the end of the year,” said Greg Beard, co-chairman and chief executive officer of Stronghold. “Earlier in the year, Stronghold chose to de-emphasize growth to focus on capital discipline and financial flexibility, and recent operational and financial initiatives, including our recent issuance of the Notes, have helped de-risk our funding needs, despite recent volatility in cryptocurrency markets.” (3) If you're long this stock, then you're liking how the stock has responded to the announcement. SDIG shares have been moving higher over the past week overall, pushing about 11% to the upside on above average trading volume. (4) Stronghold Digital Mining Inc. (Nasdaq:SDIG) managed to rope in revenues totaling $28.7M in overall sales during the company's most recently reported quarterly financial data -- a figure that represents a rate of top line growth of 655.6%, as compared to year-ago data in comparable terms. In addition, the company is battling some balance sheet hurdles, with cash levels struggling to keep up with current liabilities ($39.3M against $124.4M, respectively). (5)   BlockQuarry Corp. (OTC US:BLQC) has a different angle, with a hybrid model that includes a large “hosting” component, where its income is guaranteed by its partner relationships no matter where the price of Bitcoin trades. Its most important partner is Bitmain Technologies, the world’s leading producer of cryptocurrency mining hardware and a leading global cryptocurrency mining firm. (6) It has also worked with another partner, Bit5ive LLC, in designing and deploying its high-performance self-contained POD5 mining pods and its current project to pair 56,000 Bitmain mining rigs with 200 megawatts of power. According to a recent update from the company, following the full deployment and activation of all 200 MW of power, BlockQuarry plans to further increase its facility to 500 MW of power, allowing for a significant further expansion in hosting and mining potential. (7) BlockQuarry Corp. (OTC US:BLQC) has continued to show strong growth and would seem to be on pace to announce another strong quarter for Q2 after reporting record numbers for Q1 of this year in a recent release, posting 1,643% topline year over year growth and nearly 6,000% growth in total assets during the period. The company also reported net income of over $3.5 million, which was up massively on a year-over-year basis from a net loss of $26 million in 2021. BLQC management also noted that it believes just the first step in its now-launched Southeast US crypto mining and hosting site will drive nearly $10 million in annualized sales going forward, with expansion ahead. President and Chair Alonzo Pierce noted, “2021 was a breakthrough year for the Company, and the investments we made during that period are already starting to pay big dividends as we begin to collect on the implementation of our Phase One hosting infrastructure. The topline exploded higher last year, and the bottom line is set to swing in our favor sharply as we get past our major fixed costs.” (8) BlockQuarry Corp. (OTC US:BLQC) is interesting because it has a different model that helps to hedge against BTC volatility. But it also has a much smaller market cap than most other commercial phase mining names, presenting more upside potential as an opportunity.   Hut 8 Mining Corp. (Nasdaq:HUT) bills itself as a cryptocurrency mining and blockchain infrastructure company, which is focused solely on mining bitcoin. The company provides investors with direct access to bitcoin, without the technical complexity or constraints of purchasing the underlying cryptocurrency. Hut 8 Mining Corp. (Nasdaq:HUT) recently announced that it increased its Bitcoin holdings by 330 in the period ending July 31. Hut 8 now has 7,736 Bitcoin in its holdings. According to the company’s release, 330 Bitcoin were generated, resulting in an average production rate of 10.61 Bitcoin per day. The company also notes that its Ethereum mining – for which it received payment in Bitcoin – generated approximately 10.7% of our total production. "We continued to deliver results, growing our stack to 7,736 Bitcoin – one of the largest holdings globally – by mining efficiently," said Jaime Leverton, CEO. "At the same time, we continue to focus on growing the uncorrelated recurring revenue within our high performance computing business and are thrilled to welcome Foundry aboard as a cloud services customer in our Mississauga data centre." (9) If you're long this stock, then you're liking how the stock has responded to the announcement. HUT shares have been moving higher over the past week overall, pushing about 12% to the upside on above average trading volume. (10) Hut 8 Mining Corp. (Nasdaq:HUT) has a significant war chest ($332.3M) of cash on the books, which must be weighed relative to about $22.5M in total current liabilities. HUT is pulling in trailing 12-month revenues of $195.1M. In addition, the company is seeing major top-line growth, with y/y quarterly revenues growing at 66.8%. (11)   Other key names in the Crypto stock space include Marathon Digital Holdings Inc. (Nasdaq:MARA), MicroStrategy Inc. (Nasdaq:MSTR), Riot Blockchain Inc. (Nasdaq:RIOT), Coinbase Global Inc. (Nasdaq:COIN), and Block Inc. (NYSE:SQ).   References: https://www.cnbc.com/2022/07/14/why-the-2022-crypto-winter-is-unlike-previous-bear-markets.html https://decrypt.co/47566/is-bitcoin-an-asset-a-commodity-or-a-currency https://finance.yahoo.com/news/stronghold-digital-mining-reports-first-200500081.html https://www.tradingview.com/chart/?symbol=SDIG https://www.marketwatch.com/investing/stock/sdig?mod=search_symbol https://www.globenewswire.com/en/news-release/2021/04/23/2215989/0/en/ISW-Holdings-Announces-Participation-at-the-H-C-Wainwright-Cryptocurrency-Blockchain-FinTech-Conference-on-April-27.html https://www.globenewswire.com/news-release/2021/09/07/2292452/0/en/ISW-Holdings-Will-Host-56-000-Miners-In-Recent-Partnership-Agreement-with-Bitmain.html https://www.otcmarkets.com/stock/BLQC/news/BlockQuarry-Completes-Phase-One-20MW-Launch-5600-Miners-Now-Online-Driving-95M-Annualized-Revs-2021-Audited-Financials-F?id=353592 https://finance.yahoo.com/news/hut-8-mining-production-operations-103000858.html https://www.tradingview.com/chart/?symbol=HUT https://www.marketwatch.com/investing/stock/hut?mod=search_symbol Read the full article

[goforcrypto]

ISW Holdings Announces Pod5 Crypto Mining Pod Set to be Powered Up on February 12

ISW Holdings Announces Pod5 Crypto Mining Pod Set to be Powered Up on February 12

LAS VEGAS, February 9, 2021 (GLOBE NEWSWIRE) – ISW Holdings, Inc. (OTC: ISWH) (“ISW Holdings” or the “Company”), a global brand management holdings company with commercial operations in Telehealth and Cryptocurrency Mining, is excited to announce that its revolutionary Pod5 Cryptocurrency Mining Pod will be powered up into full operational launch at the Bit5ive renewable energy cryptocurrency…

[cancersfakianakis1]

Evaluating the Regulatory Immunomodulation Effect of Irreversible Electroporation (IRE) in Pancreatic Adenocarcinoma

Abstract

Background

Irreversible electroporation (IRE) has been demonstrated as an effective local method for locally advanced (stage 3) pancreatic adenocarcinoma. Immune regulatory T cells (Tregs) induce immunosuppression of tumors by inhibiting patients’ anti-tumor adaptive immune response. This study aimed to evaluate the immunomodulation effect of IRE to identify an ideal time point for potential adjuvant immunotherapy.

Methods

This study prospectively evaluated an institutional review board-approved study of patients undergoing either in situ IRE or pancreatectomy. Patient blood samples were collected at different time points (before surgery [preOP] and on postoperative day [POD] 1, POD3, and POD5). Peripheral blood mononuclear cells (PBMCs) were isolated and evaluated for three different CD4 + Treg subsets (CD25 + CD4 +, CD4 + CD25 + FoxP3 +, CD4 + CD25 + FoxP3 −) by flow cytometry and analyzed for median fold change (MFC) between each two consecutive time points (MFC = log2(T2/T1)).

Results

The study analyzed 15 patients with in situ IRE (n = 11) or pancreatectomy (PAN) (n = 4). In both groups, CD25 + CD4 + Tregs decreased on POD1 followed by a steady increase in pancreatectomy, whereas the trend in the IRE group reversed between D3 and D5 (MFC: IRE [− 0.01], PAN [+ 0.39]). For each period, CD4 + CD25 + FoxP3 + Tregs showed the most dramatic inverse effect, with D3 to D5 showing the most change (MFC: IRE [− 0.18], PAN [+ 0.39]). Also, CD4 + CD25 + FoxP3 − Tregs showed an inverse effect between D3 and D5 (MFC: IRE [− 0.25], PAN [+ 0.49]). Altogether, the Treg trend was inversely affected by the in situ IRE procedure, with the greatest cumulative significant change for all three Treg subsets between D3 and D5 (MFC ± SEM: IRE [− 0.24 ± 0.05], PAN [+ 0.37 ± 0.02]; p = 0.016).

Conclusions

The study data suggest that in situ IRE procedure-mediated Treg attenuation between POD3 and POD5 can provide a clinical window of opportunity for potentiating clinical efficacy in combination with immunotherapy.

http://bit.ly/2RAOHkA

[avatarthelegbender]

6/12 POD 5: SLR

[easyeartraining]

“Whole” and “half” steps are the building blocks of melodies, chords and all the pitches you hear in music and getting to know them in detail yourself opens up all kinds of exciting musicality potential. Get started today! http://musl.ink/pod5

[diyanah10]

POWEEK1

well, really there’s not much to do. not much to complain about. i’m actually healing very well. Alhamdullilah. well, there’s bone pains. I did patella graft, so i’m assuming it’s where the tibial portion was cut off? and also the screws on the tibia. hurts quite bad actually. especially during heel slides. was hoping it’d get better but it’s just getting worse. hah. definitely going to ask my surgeon and physio if it’s normal.

So, the swelling has majorly reduced, but fluctuates when i think i’m a superhero and walk excessively in school and refuse to elevate. lesson learnt, just elevate the freaking leg, it’s tiring to be in 90 degrees hip flexion perpetually everyday but it helps with the swelling. i stand by it. also, if it’s painful don’t bother with the painkillers. i just use ice(cryocuff) to numb my bone pains.

So by POD3 i managed to get PROM 0-90 degrees, then shit. i’m only meeting my physio for another week. right? so what to do friends? i dropped my physio a text, requesting that i’m allowed to actively do it and also go on one crutch occasionally (erm i’m perpetually on one crutch at home, dk if it’s a great idea to be doing it for so long). She gave me the green light obviously. been doing hip exercises while standing too (just hip abduction and extension of the injured leg). SLR with the last two reps focusing on reducing quads lag. (disclaimer i only did the refocusing the past two days since it didn’t hurt to contract my patella anymore). so yeah, conclusion is that my personal rehab is going splendid and it’s healing well.

Concluded that being a physio student also sucks or maybe someone who has her whole protocol in her face. people tell me to take it slow blablabla. but lol athelete + physio knowledge = slow slow week 1. in any case, if you dk what’s coming and you just follow your physio’s advice i’m pretty sure it’s a pretty fast week. i went back to school on POD5, felt fine but obviously as mentioned before. too much walking. so my knee ballooned up. decided to be a good girl for three days before seeing my surgeon tomorrow and the knee looks good!

another extremely irritating thing is being LOCKED IN EXTENSION. it’s the worst. yes, even more annoying than crutches. but well at least i’m allowed to put weight yeah. okay, more coming up after my first physio session on Tuesday!

[degoodlife]

In an effort to try something new on Tumblr and being the universal musical enthusiast i am ill be posting a new song each day i feel deserves to just be kicked back and chilled to.

Want to suggest a song?

-Easy, just Send me an Ask with the name of the song and who its by, it’s that simple-

Here’s Day 5 :

Jaymes Young - Fragments

[blockcain-news]

ISWH and the Rebirth of the <b>Crypto</b> Cycle

In addition, Bit5ive is the producer and distributor of POD5 and Power Skid 2.5, the most efficient and successful infrastructure for crypto mining ... from Google Alert - Crypto https://ift.tt/2VrMGrD via IFTTT

[itswallstreetpr]

All Eyes on ISW Holdings (OTC US:ISWH) After Announcement of Partnership with Bitmain

ISW Holdings (OTC US:ISWH) is quickly maturing into one of the most interesting speculative plays in the cryptocurrency space in the stock market, especially after its announcement last week of a long-term partnership with crypto giant Bitmain. The ISWH story really revolves around the company’s partnership with Bit5ive LLC last summer. Bit5ive, as many readers are likely aware, is North America’s largest provider of collective management of renewable, clean energy crypto mining services and equipment. The partnership between ISWH and Bit5ive was done as a JV within which the companies designed the POD5 mining solution – a fully self-contained high-PUE mining solution designed for installation and plug-and-play mining capability. It’s basically a shipping container – like what you see on the back of an 18-wheeler on the highway – filled with hundreds of mining rigs and a fair amount of environmental management resources to maintain systematic control over functionality, temperature, and efficiency.  According to company materials, each POD5 unit can generate around $2.9 million in crypto-mining revenues per year at current coin pricing.   Georgia on my Mined One very important recent release by ISW Holdings (OTC US:ISWH) was its announcement that it has finalized its land lease development agreement, which grants the Company full use of a 1st phase 7-acre parcel of property in Georgia tailored for cryptocurrency mining operations, complete with access to energy resources capable of powering over 100 MW of cryptocurrency mining capacity.  In other words, it has secured property in GA with huge power resources for a mix of hosting and mining activities. “This agreement puts us in position to scale up into a top-five global cryptocurrency mining position by volume,” remarked ISW Holdings President and Chairman, Alonzo Pierce.  “We control an ideal plot of land, to initiate the 1st phase with additional access to over 100 megawatts of power for use in crypto mining. We also have our close partner Bit5ive, LLC – North America’s largest provider of collective management of renewable, clean energy services and mining equipment – right on premises to manage and develop the mining operations at the site. China is cracking down hard and shutting down its domestic crypto mining industry. This has enormous consequences because more than half of the world’s cryptocurrency mining has been taking place in China. As a result, we are already fielding calls from mining firms seeking a new home. We are now equipped to handle this at scale. We have the power!” They do indeed.   Enter Bitmain Bitmain, based in China, is possibly the most well-known name in cryptocurrency mining of any company in the world. That makes it awfully big news that ISW Holdings (OTC US:ISWH) just announced a long-term partnership with Bitmain. The two companies signed an agreement that ISWH believes will form the backbone of its Phase One launch of its cryptocurrency hosting and mining operation in Georgia.  ISWH management says it believes the deal could drive as much as $200 million in annualized revenues based on power commitments and cryptocurrency pricing. Irene Gao, Antminer BD Director NCSA Region, Bitmain, said, "We are excited to have signed this new pioneering project to begin cooperation with ISW Holdings, a new milestone for the industry for creating hosting facilities overseas. The 200 MW facility is the first phase of our long-term partnership, utilizing renewable energy as its source. We expect to further expand this project into the future to support the development of the industry." “Bitmain is probably the most recognizable name in the mining space, and we are excited that they will be a major piece of our success in Georgia,” remarked Pierce. “Once our 200 MW power tranche is fully utilized, we anticipate annualized revenues of over $200 million, but that will only close the first phase of our vision. We look forward to discussing our next phases in due course. If we are able to execute according to our full vision, we have the potential to drive exponential revenue growth ahead.” The Next Chapter? ISWH management also noted in its release that a recent crackdown in China has taken roughly 54% of the global hashrate offline. This resulted in the largest ever single day easing of bitcoin mining difficulty (~28%) through the bitcoin algorithm adjustment that took place on Saturday, July 3, 2021. It has also resulted in increased demand for cryptocurrency hosting services outside of China as mining operations seek to relocate geographically. ISWH is not as well known as some of the other key stocks in the crypto space – names like HIVE Blockchain Technologies Ltd (NASDAQ:HVBT), MicroStrategy Incorporated (NASDAQ:MSTR), Marathon Digital Holdings Inc (NASDAQ:MARA), Riot Blockchain Inc (NASDAQ:RIOT), Coinbase Global Inc (NASDAQ:COIN), Bitfarms Ltd (CVE:BITF), and Grayscale Bitcoin Trust (Btc) (OTC US:GBTC). However, we would point to the company’s ability to ink a long-term deal with Bitmain as clear evidence that ISWH is rapidly rising in status and could be on its way toward global top-five positioning as a publicly traded crypto miner – something the market hasn’t remotely discounted in pricing ISWH shares. Read the full article

[avatarthelegbender]

6/12 POD 5: range of motion

[avatarthelegbender]

6/12 POD 5: mini bike