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#scientific research institutes
science70 · 5 months
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Ukrainian Institute of Scientific and Technological Research and Development, Kiev, Ukraine, 1971.
Architects: Lev Novikov, Florian Turiev
Photography: Johansen Krause
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quenthel · 7 months
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do ppl really have "university graduate" in their tumblr bios?? like uhm hello... is that a flex? is this linkedin?? kind of a weird place to showcase that but ok
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pia-writes-things · 25 days
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We love giving our master's pre-thesis to our apprenticeship tutor so they can proofread it, and all they have to say is that's it's "too political" and "too controversial", that I should "censor" (no jokes, they used that word) the extract of my field diary that's in it, that I should delete or rewrite one of my hypothesis and, finally, that interviewing teachers for my research is "too delicate".
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sopranoentravesti · 1 month
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Sorry to be a member of the intelligentsia on main, but I’m really not interested in hearing your takes on psychology or neuroscience when you get all your information from YouTube videos and refuse to read a book or a paper on whatever your chosen topic du jour is
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baejax-the-great · 9 months
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Some people are not meant to succeed at things and if i think back to all my scientific grant application responses, I think I remember some PI out there very bluntly and confidently telling me I was one of them
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thebotanicalarcade · 3 months
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n407_w1150
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n407_w1150 by Biodiversity Heritage Library Via Flickr: Geraniaceae : London :Printed for James Ridgway, Piccadilly,1820-1830. biodiversitylibrary.org/page/47460953
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postcard-from-the-past · 11 months
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Snake nursery in the Scientific Research Institute of São Paulo, Brazil
Brazilian vintage postcard
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itlearns · 4 months
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I wish Magnus Archives had a character who loves working in there. Or at least someone with Stockholm syndrome.
Probably coz I would be the first one to apply for a job if I found out The Eye was a thing and these bitches just so busy talking about what being human means and trust and blah blah blah I don't care.
Ṫ̶̢̧̛͉͎̫̦̙̺̠͚͔̮̿̈̓̋̃͐̄̀̄̊͐̕͝ͅh̵̙̮͔͑͆̃̎̊̌͐̀͝͝e̴̩͙͇̦̞̰̪̫̻̺͍̪̫͎̱͊̔̿́̀͛͗̄̕ ̷̺̈́̆̊K̸̨̢̭̬̝̮̇̒́͂͆̕͜͜ņ̵͕̭̭͈̻͔͊̒̿o̷͔̰̭͗̆͌̇̔͗̀̾̈́̅̔̍̽͠͝w̵̡̛͇̖̰̅́̎͂l̶̯̘̩͓̣̟̻̞͕͙̺̝͈̈́̕e̵̟̦̗̣͉̜̜͕͕̥̒̽́̒̄͝͠d̶̢͕̗̻̪̃̉̑͜͠ģ̷͖͕̬̂̎̊̾̐̀͛̆̏̈́̇͠ẹ̴̢̢̹̺̭̦͎̽̍̋̔̚. Hand it over.
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pwrn51 · 7 months
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The Challenges Securing Support for Research
  Today’s guest is Benjamin Lewin, Ph.D., a renowned molecular biologist and the founding Editor of “Nature New Biology” in 1971. He played a pivotal role at the National Cancer Institute from 1972 to 1973 and went on to establish a “Cell” journal in Cambridge, Massachusetts in 1974, where he remained Editor until 1999. Under his leadership, “Cell” ascended to the top-ranked position in the life…
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tenth-sentence · 7 months
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Americans eager to pursue such research were thrown back upon the resources of state universities, which at the time were willing to invest little in the field, or upon what between the wars was the principal patron of the science in the United States, the Rockefeller Foundation, which was something of a private precursor to the National Science Foundation and National Institutes of Health combined.
"In the Name of Eugenics: Genetics and the Uses of Human Heredity" - Daniel J. Kevles
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inconspicuousnpc · 1 year
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where is the scientific paper testing how stupid the research paper format is to read
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“I loathe that word ‘pristine.’ There have been no pristine systems on this planet for thousands of years,” says Kawika Winter, an Indigenous biocultural ecologist at the University of Hawaiʻi at Mānoa. “Humans and nature can co-exist, and both can thrive.” For example, in the Proceedings of the National Academy of Sciences (PNAS) in April, a team of researchers from over a dozen institutions reported that humans have been reshaping at least three-quarters of the planet’s land for as long as 12,000 years. In fact, they found, many landscapes with high biodiversity considered to be “wild” today are more strongly linked to past human land use than to contemporary practices that emphasize leaving land untouched. This insight contradicts the idea that humans can only have a neutral or negative effect on the landscape. Anthropologists and other scholars have critiqued the idea of pristine wilderness for over half a century. Today new findings are driving a second wave of research into how humans have shaped the planet, propelled by increasingly powerful scientific techniques, as well as the compounding crises of climate change and biodiversity loss. The conclusions have added to ongoing debates in the conservation world—though not without controversy. In particular, many discussions hinge on whether Indigenous and preindustrial approaches to the natural world could contribute to a more sustainable future, if applied more widely.
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"Don't spy on a privacy lab" (and other career advice for university provosts)
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This is a wild and hopeful story: grad students at Northeastern successfully pushed back against invasive digital surveillance in their workplace, through solidarity, fearlessness, and the bright light of publicity. It’s a tale of hand-to-hand, victorious combat with the “shitty technology adoption curve.”
What’s the “shitty tech adoption curve?” It’s the process by which oppressive technologies are normalized and spread. If you want to do something awful with tech — say, spy on people with a camera 24/7 — you need to start with the people who have the least social capital, the people whose objections are easily silenced or overridden.
That’s why all our worst technologies are first imposed on refugees -> prisoners -> kids -> mental patients -> poor people, etc. Then, these technologies climb the privilege gradient: blue collar workers -> white collar workers -> everyone. Following this pathway lets shitty tech peddlers knock the rough edges off their wares, inuring us all to their shock and offense.
https://pluralistic.net/2022/08/21/great-taylors-ghost/#solidarity-or-bust
20 years ago, if you ate dinner under the unblinking eye of a CCTV, it was because you were housed in a supermax prison. Today, it’s because you were unwise enough to pay hundreds or thousands of dollars for “home automation” from Google, Apple, Amazon or another “luxury surveillance” vendor.
Northeastern’s Interdisciplinary Science and Engineering Complex (ISEC) is home to the “Cybersecurity and Privacy Institute,” where grad students study the harms of surveillance and the means by which they may be reversed. If there’s one group of people who are prepared to stand athwart the shitty tech adoption curve, it is the CPI grad students.
Which makes it genuinely baffling that Northeastern’s Senior Vice Provost for Research decided to install under-desk heat sensors throughout ISEC, overnight, without notice or consultation. The provost signed the paperwork that brought the privacy institute into being.
Students throughout ISEC were alarmed by this move, but especially students on the sixth floor, home to the Privacy Institute. When they demanded an explanation, they were told that the university was conducting a study on “desk usage.” This rang hollow: students at the Privacy Institute have assigned desks, and they badge into each room when they enter it.
As Privacy Institute PhD candidate Max von Hippel wrote, “Reader, we have assigned desks, and we use a key-card to get into the room, so, they already know how and when we use our desks.”
https://twitter.com/maxvonhippel/status/1578048837746204672
So why was the university suddenly so interested in gathering fine-grained data on desk usage? I asked von Hippel and he told me: “They are proposing that grad students share desks, taking turns with a scheduling web-app, so administrators can take over some of the space currently used by grad students. Because as you know, research always works best when you have to schedule your thinking time.”
That’s von Hippel’s theory, and I’m going to go with it, because the provost didn’t offer a better one in the flurry of memos and “listening sessions” that took place after the ISEC students arrived at work one morning to discover sensors under their desks.
This is documented in often hilarious detail in von Hippel’s thread on the scandal, in which the university administrators commit a series of unforced errors and the grad students run circles around them, in a comedy of errors straight out of “Animal House.”
https://twitter.com/maxvonhippel/status/1578048652215431168
After the sensors were discovered, the students wrote to the administrators demanding their removal, on the grounds that there was no scientific purpose for them, that they intimidated students, that they were unnecessary, and that the university had failed to follow its own rules and ask the Institutional Review Board (IRB) to review the move as a human-subjects experiment.
The letter was delivered to the provost, who offered “an impromptu listening session” in which he alienated students by saying that if they trusted the university to “give” them a degree, they should trust it to surveil them. The students bristled at this characterization, noting that students deliver research (and grant money) to “make it tick.”
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[Image ID: Sensors arrayed around a kitchen table at ISEC]
The students, believing the provost was not taking them seriously, unilaterally removed all the sensors, and stuck them to their kitchen table, annotating and decorating them with Sharpie. This prompted a second, scheduled “listening session” with the provost, but this session, while open to all students, was only announced to their professors (“Beware of the leopard”).
The students got wind of this, printed up fliers and made sure everyone knew about it. The meeting was packed. The provost explained to students that he didn’t need IRB approval for his sensors because they weren’t “monitoring people.” A student countered, what was being monitored, “if not people?” The provost replied that he was monitoring “heat sources.”
https://github.com/maxvonhippel/isec-sensors-scandal/blob/main/Oct_6_2022_Luzzi_town_hall.pdf
Remember, these are grad students. They asked the obvious question: which heat sources are under desks, if not humans (von Hippel: “rats or kangaroos?”). The provost fumbled for a while (“a service animal or something”) before admitting, “I guess, yeah, it’s a human.”
Having yielded the point, the provost pivoted, insisting that there was no privacy interest in the data, because “no individual data goes back to the server.” But these aren’t just grad students — they’re grad students who specialize in digital privacy. Few people on earth are better equipped to understand re-identification and de-aggregation attacks.
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[Image ID: A window with a phrase written in marker, ‘We are not doing science here’ -Luzzi.]
A student told the provost, “This doesn’t matter. You are monitoring us, and collecting data for science.” The provost shot back, “we are not doing science here.” This ill-considered remark turned into an on-campus meme. I’m sure it was just blurted in the heat of the moment, but wow, was that the wrong thing to tell a bunch of angry scientists.
From the transcript, it’s clear that this is where the provost lost the crowd. He accused the students of “feeling emotion” and explaining that the data would be used for “different kinds of research. We want to see how students move around the lab.”
Now, as it happens, ISEC has an IoT lab where they take these kinds of measurements. When they do those experiments, students are required to go through IRB, get informed consent, all the stuff that the provost had bypassed. When this is pointed out, the provost says that they had been given an IRB waiver by the university’s Human Research Protection Program (HRPP).
Now a prof gets in on the action, asking, pointedly: “Is the only reason it doesn’t fall under IRB is that the data will not be published?” A student followed up by asking how the university could justify blowing $50,000 on surveillance gear when that money would have paid for a whole grad student stipend with money left over.
The provost’s answers veer into the surreal here. He points out that if he had to hire someone to monitor the students’ use of their desks, it would cost more than $50k, implying that the bill for the sensors represents a cost-savings. A student replies with the obvious rejoinder — just don’t monitor desk usage, then.
Finally, the provost started to hint at the underlying rationale for the sensors, discussing the cost of the facility to the university and dangling the possibility of improving utilization of “research assets.” A student replies, “If you want to understand how research is done, don’t piss off everyone in this building.”
Now that they have at least a vague explanation for what research question the provost is trying to answer, the students tear into his study design, explaining why he won’t learn what he’s hoping to learn. It’s really quite a good experimental design critique — these are good students! Within a few volleys, they’re pointing out how these sensors could be used to stalk researchers and put them in physical danger.
The provost turns the session over to an outside expert via a buggy Zoom connection that didn’t work. Finally, a student asks whether it’s possible that this meeting could lead to them having a desk without a sensor under it. The provost points out that their desk currently doesn’t have a sensor (remember, the students ripped them out). The student says, “I assume you’ll put one back.”
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[Image ID: A ‘public art piece’ in the ISEC lobby — a table covered in sensors spelling out ‘NO!,’ surrounded by Sharpie annotations decrying the program.]
They run out of time and the meeting breaks up. Following this, the students arrange the sensors into a “public art piece” in the lobby — a table covered in sensors spelling out “NO!,” surrounded by Sharpie annotations decrying the program.
Meanwhile, students are still furious. It’s not just that the sensors are invasive, nor that they are scientifically incoherent, nor that they cost more than a year’s salary — they also emit lots of RF noise that interferes with the students’ own research. The discussion spills onto Reddit:
https://www.reddit.com/r/NEU/comments/xx7d7p/northeastern_graduate_students_privacy_is_being/
Yesterday, the provost capitulated, circulating a memo saying they would pull “all the desk occupancy sensors from the building,” due to “concerns voiced by a population of graduate students.”
https://twitter.com/maxvonhippel/status/1578101964960776192
The shitty technology adoption curve is relentless, but you can’t skip a step! Jumping straight to grad students (in a privacy lab) without first normalizing them by sticking them on the desks of poor kids in underfunded schools (perhaps after first laying off a computer science teacher to free up the budget!) was a huge tactical error.
A more tactically sound version of this is currently unfolding at CMU Computer Science, where grad students have found their offices bugged with sensors that detect movement and collect sound:
https://twitter.com/davidthewid/status/1387909329710366721
The CMU administration has wisely blamed the presence of these devices on the need to discipline low-waged cleaning staff by checking whether they’re really vacuuming the offices.
https://twitter.com/davidthewid/status/1387426812972646403
While it’s easier to put cleaners under digital surveillance than computer scientists, trying to do both at once is definitely a boss-level challenge. You might run into a scholar like David Gray Widder, who, observing that “this seems like algorithmic management of lowly paid employees to me,” unplugged the sensor in his office.
https://twitter.com/davidthewid/status/1387909329710366721
This is the kind of full-stack Luddism this present moment needs. These researchers aren’t opposed to sensors — they’re challenging the social relations of sensors, who gets sensed and who does the sensing.
https://locusmag.com/2022/01/cory-doctorow-science-fiction-is-a-luddite-literature/
[Image ID: A flier inviting ISEC grad students to attend an unadvertised 'listening session' with the vice-provost. It is surmounted with a sensor that has been removed from beneath a desk and annotated in Sharpie to read: 'If found by David Luzzi suck it.']
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thebotanicalarcade · 3 months
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n407_w1150 by Biodiversity Heritage Library Via Flickr: Geraniaceae : London :Printed for James Ridgway, Piccadilly,1820-1830. biodiversitylibrary.org/page/47410194
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jewish-sideblog · 2 months
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I think people forget that the Nazis never said they were the bad guys. If someone says, hey, I’m evil! You don’t let them take over your country. They presented themselves as scientific, not hateful. By their own account, they were progressives, and the superiority of White Europe over the other races was a proven and immutable fact. They had scientists and archaeologists and historians to prove it. They didn’t tell people they wanted to kill the Jews because they were hateful. They manufactured evidence to frame us for very real tragedies, and they had methodological research to prove that we were genetically predisposed to misconduct. Wouldn’t you believe that?
Hollywood has spent the last 80 years portraying the Nazis as an obvious and intimidating evil. That’s a good thing in some ways, because we want general audiences to recognize that they were evil. But we also want them to be able to recognize how and why they came to power. Not by self-describing themselves as an evil empire, but by convincing people that they were the good guys and the saviors. They hosted the Olympics. Several European countries capitulated and volunteered themselves to the Empire. There were American and British Fascist Parties. They had broad public support. Hollywood never shows that part, so general audiences never learn to recognize the actual signs of antisemitism.
People today think they can’t possibly be antisemitic, because they’re leftist! They abhor bigotry! They could never comprehend Nazi ideology coming from the mouth of a bisexual college student wearing a graphic tee and jeans. How could they? The only depiction of antisemites they’ve ever seen have been gaunt, pale, middle-aged men in black leather trench coats with skulls on their caps.
If the Nazis time-travelled from the 1930s and wanted to take power now, they’d change their original tactics, but not by much. They would target countries suffering from an identity crisis and an economic collapse. They would portray themselves as the pinnacle of what that society considers progressive. Back then, it was race science. These days it’s performative wokeness. Once they’d garnered enough respect and reputation, they’d begin manufacturing propaganda and lies to manipulate people’s anger and fears at a single target— Jews.
If the Nazis made an actual return, they wouldn’t look like neo-Nazis. They wouldn’t be nearly as obvious about their hatred. Their evil wouldn’t give them yellow eyes, and no suspenseful music would play when they walked in the room. They’d be friendly. They’d look like you. They would learn what things your community fears and what things you already hate. They would lie and fabricate evidence to connect the rich elites and the imperialists you revile to a single source of unequivocal Jewish evil. It wouldn’t be hard— they already have two-thousand years of institutional antisemitism they can rely on to paint their picture.
If you’re curious why antisemitism today is coming from grassroots organizations, young, liberal college campuses, suburban neighborhoods with pride flags and All Are Welcome Here signs? That’s why. It’s because, as a global society, we’ve forgotten that the world didn’t used to see the Nazis as bad guys. And what is forgotten about history is doomed to be repeated.
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reasonsforhope · 13 days
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"Since it was first identified in 1983, HIV has infected more than 85 million people and caused some 40 million deaths worldwide.
While medication known as pre-exposure prophylaxis, or PrEP, can significantly reduce the risk of getting HIV, it has to be taken every day to be effective. A vaccine to provide lasting protection has eluded researchers for decades. Now, there may finally be a viable strategy for making one.
An experimental vaccine developed at Duke University triggered an elusive type of broadly neutralizing antibody in a small group of people enrolled in a 2019 clinical trial. The findings were published today [May 17, 2024] in the scientific journal Cell.
“This is one of the most pivotal studies in the HIV vaccine field to date,” says Glenda Gray, an HIV expert and the president and CEO of the South African Medical Research Council, who was not involved in the study.
A few years ago, a team from Scripps Research and the International AIDS Vaccine Initiative (IAVI) showed that it was possible to stimulate the precursor cells needed to make these rare antibodies in people. The Duke study goes a step further to generate these antibodies, albeit at low levels.
“This is a scientific feat and gives the field great hope that one can construct an HIV vaccine regimen that directs the immune response along a path that is required for protection,” Gray says.
-via WIRED, May 17, 2024. Article continues below.
Vaccines work by training the immune system to recognize a virus or other pathogen. They introduce something that looks like the virus—a piece of it, for example, or a weakened version of it—and by doing so, spur the body’s B cells into producing protective antibodies against it. Those antibodies stick around so that when a person later encounters the real virus, the immune system remembers and is poised to attack.
While researchers were able to produce Covid-19 vaccines in a matter of months, creating a vaccine against HIV has proven much more challenging. The problem is the unique nature of the virus. HIV mutates rapidly, meaning it can quickly outmaneuver immune defenses. It also integrates into the human genome within a few days of exposure, hiding out from the immune system.
“Parts of the virus look like our own cells, and we don’t like to make antibodies against our own selves,” says Barton Haynes, director of the Duke Human Vaccine Institute and one of the authors on the paper.
The particular antibodies that researchers are interested in are known as broadly neutralizing antibodies, which can recognize and block different versions of the virus. Because of HIV’s shape-shifting nature, there are two main types of HIV and each has several strains. An effective vaccine will need to target many of them.
Some HIV-infected individuals generate broadly neutralizing antibodies, although it often takes years of living with HIV to do so, Haynes says. Even then, people don’t make enough of them to fight off the virus. These special antibodies are made by unusual B cells that are loaded with mutations they’ve acquired over time in reaction to the virus changing inside the body. “These are weird antibodies,” Haynes says. “The body doesn’t make them easily.”
Haynes and his colleagues aimed to speed up that process in healthy, HIV-negative people. Their vaccine uses synthetic molecules that mimic a part of HIV’s outer coat, or envelope, called the membrane proximal external region. This area remains stable even as the virus mutates. Antibodies against this region can block many circulating strains of HIV.
The trial enrolled 20 healthy participants who were HIV-negative. Of those, 15 people received two of four planned doses of the investigational vaccine, and five received three doses. The trial was halted when one participant experienced an allergic reaction that was not life-threatening. The team found that the reaction was likely due to an additive in the vaccine, which they plan to remove in future testing.
Still, they found that two doses of the vaccine were enough to induce low levels of broadly neutralizing antibodies within a few weeks. Notably, B cells seemed to remain in a state of development to allow them to continue acquiring mutations, so they could evolve along with the virus. Researchers tested the antibodies on HIV samples in the lab and found that they were able to neutralize between 15 and 35 percent of them.
Jeffrey Laurence, a scientific consultant at the Foundation for AIDS Research (amfAR) and a professor of medicine at Weill Cornell Medical College, says the findings represent a step forward, but that challenges remain. “It outlines a path for vaccine development, but there’s a lot of work that needs to be done,” he says.
For one, he says, a vaccine would need to generate antibody levels that are significantly higher and able to neutralize with greater efficacy. He also says a one-dose vaccine would be ideal. “If you’re ever going to have a vaccine that’s helpful to the world, you’re going to need one dose,” he says.
Targeting more regions of the virus envelope could produce a more robust response. Haynes says the next step is designing a vaccine with at least three components, all aimed at distinct regions of the virus. The goal is to guide the B cells to become much stronger neutralizers, Haynes says. “We’re going to move forward and build on what we have learned.”
-via WIRED, May 17, 2024
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