#this was from multiple soc Saturdays

[ithinkivegoneferal]

Guys to take away some of the pain of rj jousha and Maggie leaving(😕☹️💔☹️😭) I have decided to share my secret outsiders list that has been formatted throughout the soc Saturdays

I present to you my outsiders cartwrel list

[breaking-it-down]

Hi. I wanted to send this to you here because it seems the Reddit is inactive. I’m /sincerely/ concerned that a new McKenna and Co are on the rise. And no, I am not here to start drama, spread hate, or bash anyone. Simply here to tell you that a new group of problematic people are showing the beginning signs of what has been called out before. I’m hoping we can just be aware of who we are putting on a pedestal. I don’t know if this was a good place to send this or not, but I assume you know better than me in how to get this information out. I’m so genuinely concerned that we are going to keep repeating this cycle.

- jasonschmidtheads — Juliana / Jude

Since she is now a very frequent attendee of the show, and is gaining a following, here are some facts. This person is one of the individuals involved with the brownie stagedoor issue from last year. When a cast member denied taking a homemade brownie from her and another person, they drunk called and voice messaged this cast member via Instagram for hours. Keep in mind, Juliana is 18, not old enough to drink.

On top of that, I know that she has called cast members’ significant others (like Daryl and Sky) the following terms: wh*re, b!tch, stripper, etc. She has stated that various cast members would get with her if they could. She is a prominent shittalker, bootleg leaker, and rushes to claim the discounted seats multiple times a week. She has also bashed cast members in messages and in verbal conversation, especially Brody. I know she is blocked by a few cast members.

- sierrahunter13 - Sierra

This person made up an entire relationship with Brent Comer, doctored fake messages / screenshots to perceive that she is dating said cast member, and is genuinely just weird to interact with. I’m sure someone has the screenshots of her story about the cast member. She is an adult but is close with many (I mean many) minors in the fandom, commenting stuff like “My girl 😍” and “Love you 😍😍” on stuff minors post. In hindsight, not a bad thing; however, if she doesn’t truly know them outside of Outsiders stuff… It’s so weird. Flies from across the country multiple times a month and acts like she knows the cast.

- tulsatripswjess - Jessica

This person has been called out before but Jess sent her little army of people to downvote and comment. I am aware she has been posted by Outsiders social media before too, but so have many others that have been called out. That doesn’t change anything. I’m here to say that it is absolutely 100% true that this person and her mother are insufferable. Flies multiple times a month to see the show, even though she is a minor. Sits front row multiple times each trip. That’s not what the issue is though!

Jess has forced people to spam the comments of Soc Saturday for the cast to notice her. She has messaged multiple fan accounts, and has started copying their ideas, posts, and everything. Literal copy paste of someone else’s account. Her and her mother have asked cast members at the stagedoor about who their vocal coaches are in the city, which in hindsight isn’t weird to ask; however, asking an actor at their job questions like that? Weird as hell. Worst of it that I have heard is that she was yelling at her mom at the stage door: “Mommy take my picture with Dan!” “Mommy take my picture with Brody!” And will throw temper-tantrums at the stage door if certain actors don’t come out. She is also in the crowd of people who publicly make stage door ahd the fandom look unsafe and unhinged, I.E. her tiktoks of her crying at the theatre when certain cast members are on / not on. Someone even called her out in the comments and the reply was “The cast knows us.” They don’t know you. They know you from your stupid shit, your whiny attitude, and your cringe antics, which really isn’t cute or funny. She acts like she owns the fandom.

I am genuinely concerned that if we don’t stop these people now, we will see McKenna and Co 2.0.

i’m genuinely so done with this fandom i swear to god…

i’ve heard shit about sierra (i have screenshots too that the person who took asked me not to share so i guess you’ll have to take my word on it which…yeah, i know how that is, i know being all “oh trust me” isn’t exactly trustworthy but yk) but still that’s a bit…weird. i dunno why so many people are hellbent on saying the cast knows them and whatnot.

i used to watch soc saturday over the summer before i was pushed out of the fandom/kinda jsut stopped watching and i remember seeing a lot of stuff with “say hi to jess! can you say hi to jess?” which is odd. i know she’s a minor, does anyone know her exact age? regardless of whether she’s 14 or 17 though that’s not an excuse to complain when a cover is on or act like an entitled brat. i think her mom’s the root of the problem tho, if she’s allowing that sort of behavior. i got genuine second hand embarrassment reading the bit about her ngl, but still. you’re allowed to be disappointed if a certain cast member isn’t on, but keep it to yourself. when i went in february, brody wasn’t on and it was kinda just a “well that sucks! anyway,” moment. like yeah, not seeing your favorite cast member kinda sucks, but it’s not the end of the world. i don’t get why people who frequent are upset whenever they don’t see their favs like they’re not gonna be back the next week, lmfao. but anyway that’s not important.

i thought the brownie girl was called out already? i suppose not though. but yeah, you’re right.

this is kinda just a little message to the outsiders musical fandom but please, please, please, for the love of god, stop putting people on a pedestal. we’re all equals in this fandom. no one person is better than the other. if you’ve seen the show on eve, you’re as much of a fan and know the same amount about a cast member as someone who’s seen the show fifty times. i don’t know why this fandom keeps fostering a community in which we tolerate behavior like this. everyone’s all for calling out, but who got them to the point of entitlement they’re at? both outside factors and the community have shaped these people. stop giving these people attention, stop putting them on a pedastol, stop encouraging this behavior. stop fostering this kind of community. people complain about the fandom being “so toxic!” but then you never do anything about it. you got them to the point of fame they’re at, you put them above everyone else. i’m aware it isn’t just the fandom’s fault, but the fandom is just gonna get worse and worse and more people are gonna see it as one of those horrible fandoms if we keep allowing people to act this way in our community.

do better.

[ineffablebooklover]

Oh goodness, I'm terrible at writing prompts, hmm......

Are you familiar with D&D/Pathfinder/tabletop RPG's in general? I'd love to see The Crows rolling up characters and playing a one-shot. I can't decide if I'd rather Kaz or Jesper be the GM. Both sound horribly great. 😆

Otherwise, in a very un-original but beloved AU, I'd love to see HP Drarry and Romione + SoC Kanej, Wesper, and Helnik in some kind of Coffee Shop setting (I owned my own shop for the better part of a decade, so I love those).

And Matthias always being alive, please, if you do either of these. ;)

And I don't care about fic length; whatever you feel inspired to do!

💜

The Crow Cafe Coffee Shop AU~ with the Crows, Ronmione, and Drarry

authors note: I got a bit carried away with the idea, and I added some plot. There’s going to be multiple parts to this (yay!) so I guess keep in tune!

Part 1. Kaz’s Crow Cafe

There is a cafe, down some streets in Downtown Ketterdam’s Stave, run by a boy and his friends. There, you can find stories, romance, and most importantly, a decent cup of coffee.

“Not for my coffee, you podge,” Kaz scoffed, slapping away Jesper’s offer of sugar with a glove-clad hand. “I’m just saying sugar prices are getting higher. We need to compensate for this fact.”

Kaz waited for questions, looking around the table. No one said anything. Kaz looked directly at Jesper, who sighed, taking back the sugar and dumping it in his own coffee.

“And how do you want us to do that?”

It was a chilly Saturday morning in early-September, and Kaz was giving his Saturday morning pre-opening briefing.

“Kaz, people come here for the low coffee prices. We can’t hike the prices really high,” Inej added. Jesper nodded, grabbing another packet of sugar.

Kaz sighed. “I know. I’m working on it. Just thought I’d let you two know.”

“Don't mind if I do,” Jesper cut in, pouring the sugar in his overly-caffeinated drink, ���but shouldn’t good old Mr. Haskell be thinking about this instead of us?”

Kaz sipped his coffee, shrugging. “‘Old Mr. Haskell’, as you say Jesper, is old and inert.” Kaz sent a glance Inej’s way. “He won’t be doing much about it.”

Jesper just chugged his coffee, bouncing up and ready to start the day.

“Jesper, was it wise to take in that much sugar and caffeine?” Inej inquired as Jesper bounced around the shop.

“Probably, not,” Jesper grinned, flipping the sign to ‘Open’ as a few early-risers started to form a line in front of the Cafe.

A girl with tied back light brown hair entered the cafe first, a stack of textbooks and notebooks in her arms. She ordered a coffee and a pastry, and started working at a table.

She was followed by a tall, burly, blond male who Kaz was sure he’d seen before. Trailing him was Nina, a girl Kaz knew from previous jobs he had done with her to help keep up the profits. Next to the composed blond dude, Nina looked dead tired.

“Why do we even have to get up this early?” Nina whined.

“I have to do things later today and Sunday, this is a good time to work on the project,” the blond replied.

Nina groaned. “Good for you. I was going to get my beauty sleep.”

“Well you get to have a beautiful coffee instead,” Jesper said cheerfully. “Good morning, Nina! What will it be for you and your…” Jesper looked the blonde up and down. “...this hunk of a man, here?”

Nina smirked tiredly. “Yeah, that’s my hunk of a man to you,” she pointed a lazy finger at Jesper.

The blond huffed. “So impudent and improper. My name is Matthias. I will have a black coffee.”

Jesper typed it into his screen quickly. “And no cream, no sugar, nothing sweet?”

Matthias shook his head.

“Anyways, I’ll have a mocha, like 10 shots of coffee and lots of creamer,” Nina cut in.

Jespers slender fingers flew across the board. “Okay so that’s one coffee as bitter as Kaz’s soul, and a mocha with 4 shots of espresso and half of it basically milk. Is that all for today?”

Nina scanned the pastry rack and ordered two chocolate chip muffins. The two sat down, getting stuff out for a project.

Meanwhile, Inej bounced around in her athletic wear, preparing coffees. She finished one for the girl named Hermione, grabbed the apple strudel she wanted, and headed over.

“Hermione?”

Hermione turned, and greeted Inej with a smile. “Thank you. I’ll take those.”

Inej noticed the bigger table Hermione had chosen, and tilted her head. “Are you waiting for someone?”

Hermione nodded. “Yes, my friends. They’re supposed to be here in about an hour, I’m just catching up on studying before they come. Is that alright with…” Hermione stared into the distance, where Kaz stood ominously staring at Inej.

“Oh he… he’s alright.,” Inej lifted a hand to wave at Kaz, who noticed and looked away. “That’s Kaz for you,” she mumbled under her breath.

“Pardon?” Hermione asked.

Inej just laughed nervously, brushing it off. “Enjoy your breakfast!” Inej went back to making coffee behind the counter watching Jesper chat up customers left and right. Inej was glad for his enthusiasm so early in the morning, she never liked taking Saturday morning shifts at 6AM, especially if they had meetings at 5:45.

“How’s it going Jesper?” Inej asked while preparing another cup. Jesper nearly jumped out of his skin.

“Holy- oh Inej. Oh Inej don’t sneak up on me like that. Besides that, I’m doing fine!”

Inej nodded and disappeared behind towers of cups and spouts of coffee. She prepared Nina’s things and brought it over. The two seemed to be arguing.

“I’m just saying- ooh, food!” Nina gasped, sitting up straight for the first time that morning. Inej smiled, placing the coffee and muffins down on the table. Matthias just watched her, arms crossed.

“Enjoy the food,” Inej smiled, then went back to the counter.

Kaz watched her silently from the side, then, noticing the line, straightened his gloves and walked over to help make coffee. They went through orders silently, Inej doing all of the walking, but they enjoyed each other's company. Inej and Kaz would work on an order or two, Kaz would place his finished ones on a counter for Inej to take. While Inej was gone, Kaz would get started on the next thing, and so on.

Eventually, Kaz went into the back and disappeared for a while, leaving Inej with the coffee work.

By this time, Hermione’s friends had come, and their study group looked like they were having a great time, though only ⅓ of them seemed to actually be doing any studying.

By 8, Inej and Jesper switched spots. Inej found that Jesper still loved people-watching, even behind the counter. Or... was he looking for someone?

Her suspicions were correct when a boy walked in, with ruddy, orange-brown curls. Jesper leaned into her, pointing him out. “I think he’s starting to be a consistent customer. At least on weekends. Have you seen him around school?”

Inej had in fact seen him around school. His name was Wylan and he was in Kaz’s math class, and in her Art and Gym class. During lunch, he was usually just drawing something or doing math homework by himself.

Inej nodded, then went back to a customer, leaving Jesper to speculate by himself.

When the boy with golden-brown curls stepped up, she asked what he wanted.

He looked up at the board for less than a second, then back to Inej. “I’ll have an iced coffee. With the cream.” Inej nodded and punched it into the computer.

“Your name?” She asked.

“Wylan,” Wylan smiled. Inej pretended to punch it in as if she hadn’t already.

“And… if you want, the Crow Cafe is thinking of starting a sort of rewards club for regular members. There’s more info up on the board, but all we need is your number,” Inej added effortlessly.

Wylan looked up at the board and back to Inej. “Uh… sure,” he said tentatively. He gave her his number and she pretended to type it in, instead writing it down on a piece of paper after he left the counter. She then looked up at the board to confirm her suspicions. There was nothing about a rewards club. So he can’t read, and yet he still pretends…

She tucked that information away, smirking as she slid the paper into Jesper’s back pocket.

Everything was going pretty smoothly (besides Nina and Matthias’ constant bickering) until the door opened and in walked the most pretentiously blond man Inej and seen, with an even blonder son.

_end of part 1_ thanks for reading, and for the commission!

next commission: Sleeping Beauty AU :)

[side-effect-of-the-meds]

Merry Christmas! May I present (hah) to you, SoC Au Part 2!

It was noon before Kaz finally reemerged from the basement. With great difficulty, he dragged himself up the three flights of stairs and rinsed the blood from his body. Squeezing between the two dogs that now occupied his bed, Kaz let his exhaustion drag him under. He had school tomorrow. Missing school was the least of Kaz’s worries but if he wanted to keep playing Exy, he knew he had to keep up both his grades and his attendance. 

Sleeping through the remainder of the day and the entire night, Kaz managed to recover some of his strength. Waking early Monday morning Kaz managed to snag his cane. Nothing looked any different from the way he’d left it. He prayed that neither Lola nor Romero had entered the office while he slept. Kaz turned the dogs loose in the backyard before grabbing a quick breakfast and headed to school. All day long, Kaz was out of it. No matter how hard he tried, he couldn’t keep his thoughts from straying back to the box in the safe. Now that he knew exactly who the man was, Kaz knew he’d be able to find something, anything, to point him in the right direction. 

Standing in his goal, Kaz watched the scrimmage, his thoughts drifting. Every member of Edison High’s Exy team had been handpicked by Kaz. None of them had been very good when they’d began. Half of them hadn’t even known the rules. Looking at them now, Kaz felt a small swell of pride in his chest that he squashed almost immediately. They’re just an investment, he told himself. 

Before Kaz, none of these kids had had anything to live for. Their lives were rendered barren and loveless by the opioids running rampant on the streets. Guidance counselors and motivational speakers were brought in each year, preaching about how life would get better. For many of them, it never did. Most kids on the streets of Baltimore grew up and fell into one of two categories: drug dealers or drug addicts. Sure, some made it out, but there weren’t nearly enough. It wasn’t that they didn’t want a way out. It was that they didn’t have one. 

Unlike many of the adults in their lives, Kaz didn’t go around spouting that bullshit. He knew his words would offer no comfort to the souls of the grieving. He knew the biting pain of being cold and alone and desperate on the brutal streets of Baltimore. He knew that it stole the will to live right out of you and making you cling fiercely to every scrap of kindness someone threw your way, no matter how cruel and unkind that person might be to others. He knew that it made people easy to manipulate and eager to please. 

Seeing an opportunity, Kaz jumped at the chance to build his own army. It took a great deal of bargaining but Kaz managed to convince Nathan to give him bigger, better jobs. The more dangerous the job, the greater the risk but with it came greater rewards. Building his reputation as Dirty Hands, Kaz racked up enough money to purchase the dilapidated hotel a few blocks down from the school. Kaz managed to finance the renovations with a loan from Nathan and opened it up to anyone that made the cut for the Exy team. 

With three meals a day, a roof over their heads, and a bed a little softer than the concrete walkways, Kaz's offer was hard to turn down. With such a big pool of applicants, there were a few kids that were already half-decent. Kids like that had no place on the lineup. Kaz didn't need a good team, he needed a desperate one. 

And they were. Every time Kaz stepped off the court he saw the ravenous glint in their eyes and it made Kaz smile. Not so long ago, they’d been the worst team in the district. Everywhere Kaz went, he heard the laughter of skeptics. 

“Poor Brekker,” Van said from his seat atop the desk in Kaz’s office. “You’ve really scraped the bottom of the barrel with this sorry excuse of a team.” 

“Look at them, Van,” Kaz said. He heard Van hop off the desk. Joining him at the window, the two of them watched the kids dragging their meager belongings up the walk.“When was the last time you saw Hutchinson smile? Or heard Cooper laugh? I’ll bet fifty bucks that today is the first time you witnessed either of those.” Kaz smiled when he saw the way Van’s expression soured. “So what if they’re the bottom of the barrel? They’ll play until their bones break and their lungs give out. So long as their hearts beat, they will fight. Do you know why?” Kaz asked.

“Greed?” Van replied, his own lips curving in a knowing smile. 

“Greed,” Kaz assented. These kids had fought tooth and nail for their place on his team. They knew, if they failed, it wasn’t just the game they lost. It was their home, their food, their whole life was on the line. Offering these kids Exy made them his. By breathing life back into the empty husks they’d been, that life was his to control.

“No one will ever believe in them. They’re the worst of the worst, Kaz. They’re those things you find at the bottom of a teacup. The…” Van scrunched his face up as he looked for the right word. “The dregs! That’s it.” After a moment’s consideration, he added. “You know that doesn’t sound half bad.” 

“The Dregs,” Kaz echoed, feeling the word roll across his tongue. Van was right, the name wasn’t half bad at all. 

The buzzer at the other end of the goal sounded, leaving the score 7-1 in Kaz’s favor. Filing off the court behind his team, Kaz let himself get dragged into a conversation about plays for Friday’s game. They had to win. If The Dregs had any chance of getting recruited for college, they were going to have to prove they were worth it. Kaz had promised his Dregs a future free of their demons and Exy was their ticket to it. 

In all honesty, Kaz’s Dregs weren’t much better of than their families had been. Anyone who knew an addict knew that their drugs were the center of their world. It was their solace, their safe haven, from the horror and misery of day to day life. Wasn’t Exy the same for the Dregs? Exy was their salvation. Exy was their solace. Exy was their everything. The Dregs were just junkies chasing a high, only better off than their drug-addicted relatives for their dependency gave them a future. Now that Kaz thought about it, no matter where he started or who he looked at, every one of the Dregs’ problems stemmed from the opioid crisis. Kaz would have to remember to thank Romero for handing him a team like this before he put him in the ground. 

Late at night, Kaz continued to hunt through the files in search of something, anything, about Romero in Nathan’s files. It wasn’t until late Saturday night that Kaz found anything. Kaz had originally decided to work backward from his arrival at the Wesninski house and found nothing. After some research, Kaz found that there had been an exponential increase in opioid users in 1984. Kaz decided to start there. He hadn’t known what exactly he’d expected to find in the files but it wasn’t this. 

There was a single unmarked drive in the subsection. Inserting it into the computer, Kaz found that it had multiple layers of encryption. Kaz slipped his phone from the pocket of his hoodie and called the only person that could help him. 

“Kaz, honey, it’s three in the morning.” Kaz could hear Van struggling to hold his temper.  

“I’m aware but it’s urgent.” On the other end, Kaz heard the sultry voice of a woman calling Van back to bed. Oh. “If you’re busy, though-” 

“What do you need, Kaz?” Before his luck could run out, Kaz explained his predicament. Half an hour later, Kaz opened the door to find Van standing at the door. Dark circles rimmed his bloodshot eyes. Shoving a cup of coffee into Kaz’s hand, Van moved past him and marched up the stairs. A small part of Kaz wanted to apologize. 

Van wasn’t like the rest of Kaz’s associates. Unlike them, Van wasn’t bound to him. There were so many things in Kaz’s life that he had no control over and it drove him mad. What if scenarios played through his head and hurled him into bouts of self-doubt that sent him careening to the brink of death. Having control over the lives of others distracted Kaz from his own growing worries. Being able to orchestrate incredible schemes, riddled with twists and turns that easily blindsided his prey reassured him of his abilities. Still, he wouldn’t be able to do it without information. For the longest time, Kaz had assumed that all he needed was information on the target: who they were, their habits, their appearance. He’d been wrong. Cons weren’t like pickpocketing. They weren’t one-off things. Kaz had found that if you wanted to be a successful con man you needed to be a bit of a renaissance man too. 

Lucky for Kaz, picking up new skills wasn’t hard. Fueled by vengeance and spite, there was very little that Kaz couldn’t teach himself how to do. Despite being a jack of many trades, coding just wasn’t something Kaz could do. He’d tried his hand at it multiple times but he simply didn’t have the knack for it. It hadn’t stopped him from trying to hack into the school’s database to dig up some dirt on his prospective teachers. Kaz never knew who he’d have to blackmail to do what but teachers seemed like people who’d need some extra convincing to get what he needed. Kaz’s own grades weren’t a problem. His team’s were. Enter Van. 

Kaz had never heard the name in his life nor could he conceive what kind of parents would name their kid that. As such, when Van first showed up in Kaz’s room uninvited, he’d rightfully lost his shit. Putting a knife to his throat and pinning him to the wall, Kaz had expected to see fear flood the boy’s eyes. To his infinite horror, Van had only pushed close until the tip of the blade bit into his flesh. Kaz watched in awe as a stream of blood trickled down from the point of his blade. 

A lazy smile stretched across Van’s face. A manic light danced in his eyes. In an all too friendly tone, he offered to help breach the school’s firewall and dig up dirt on every member of Edison High’s staff. When asked why he’d help, Van had only shrugged. 

“Why not?” he’d countered. “It’ll be fun.” Kaz had been skeptical but allowed Van to try his hand anyway. It had taken him no more than a few hours to dredge the deepest, darkest parts of the internet and find something on each and every member of, not only the school’s faculty, but their families, and the entire board of education. Kaz couldn’t refuse that kind of help. Van became Kaz’s biggest asset and, along the way, someone he’d come to lean on far more than he’d meant too. 

It wasn’t often that Kaz went anywhere without Van. Kaz didn’t actively seek the boy out. No, Van just had a habit of appearing wherever Kaz went. It irked him to not know how Van kept managing to follow him without getting detected. Not knowing his motives or being able to control him, scared Kaz far more. 

Kaz tried not to stare at Van as he worked. Nestled on the floor on a bed of sheets, surrounded by the dogs, Van seemed to genuinely relax. Kaz knew that Van’s usual laid-back attitude was a facade, but he’d never quite figured out what it was Van was trying to hide. On the list of problems in Kaz’s life, Van ranked just beneath his vengeance for Romero. Van had never done anything to harm Kaz. Not yet at least, but Kaz couldn’t help but fear that one of these days, Van was going to flip on him. 

“Why don’t you give up?” Van asked, not taking his eyes off the screen. His voice startled Kaz from his thoughts and he floundered for an answer. “You’re never going to solve me.” Kaz scowled. Van looked over then and smiled. It was the same lazy smile he’d given him when Kaz had pressed that knife to his throat. “Ask me.” For the last two years, Kaz had hunted for something, anything, that might have given him a clue as to who Van might be. Questioning people had come up empty. Few people knew he existed. Even fewer knew what he looked like. Van was a ghost. Kaz couldn’t even find his name in the Social Security database. Van was a nickname, short for God knew what, and every attempt to find his last name had hit a wall. 

“What’s your last name?” Kaz asked, knowing very well he wouldn’t get a straight answer. 

“Don’t have one. Maybe you could give me yours.” Van winked at him. Kaz wadded up a scrap sheet of paper and chucked it at his head. “It was worth a try,” Van said as he passed the laptop back over. He’d done it. Of course, he had. Kaz had yet to find a firewall that Van couldn’t breach nor a system he couldn’t hack. Kaz would have to find a way to put a leash on this kid and soon. 

Gathering the blankets up from beneath him, Van threw them over himself before curling up between the dogs. With a groggy ‘good-morning’, he fell asleep. Turning his attention to the screen, Kaz felt a thrill go down his spine. This was it. He was finally going to find the proof he needed to nail Romero. He could feel it in his bones. Romero would be sent to prison in disgrace only to be found dead in his cell days later. A wicked smile curled the edges of Kaz’s lips as he thought of all the things he would do to him. Romero’s death would not be quick or easy. No, Kaz had to pay him back for ten years worth of suffering. Opening the drive, Kaz found a single folder. Lenimen Parem, it read.

Of all of Kaz’s ridiculous obsessions, learning dead languages was his hardest to defend. Sure, knowing Greek and Latin roots gave him a deeper understanding of words but he’d yet to find a use for it. Until now. Lenimen Parem. 

“Better solace,” Kaz whispered. Feeling infinitely more pleased with himself than he should, Kaz navigated to the folder to inspect its contents. In it, he found scanned copies of handwritten chemists’ notes. Fractions were scrawled beside barely legible elements. Compounds were labeled in the order in which they’d been mixed. Scrutinizing the notes written beside each failed attempt, Kaz struggled to discern the purpose of these experiments. Slowly but surely, the sun’s rays snuck up between the shafts of the blinds and spilled through the curtains hung over the windows. Sleep threatened to drag Kaz under, lulling him with sweet words and seducing him with assurances of rest. After all, the drive could wait until tomorrow couldn’t it?

“Sleep, Kasimir,” Jordie cooed. “Tomorrow, I’ve got to run a little errand and then I’ll take you to the pier. How does that sound, lieve schatje?” 

“M’kay,” Kaz mumbled, his eyes fluttering shut. They were only closed for a few seconds before Kaz jolted awake. They’d never gone to the pier. They’d made it halfway there before Jordie and his friends caved and found a little alleyway where they’d be safe from prying eyes. A greedy light had danced in their eyes as they dug out their needles and their newest bottles. Kaz had begged Jordie not to do it. Jordie had shoved him away before inserting his needle into the soft cork of his bottle. Pain at the memories of their past life had driven Jordie to opioids. He’d sought solace in them. 

Lenimen Parem. Better solace. Kaz felt his heart stutter. Opioids. Nathan had been creating a new strain of opioids. Frantically, Kaz searched through the labels and formulas listed. The final listing was for a strain called Jurda. Reading through the notes beside it, Kaz felt his chest tighten with every passing sentence. By the end, he could barely breathe. 

Nathan’s purpose in Lenimen Parem had not been to simply heighten the experience of the drug. It was to heighten the addictive properties of it too. And he’d done it. Nathan had managed to manufacture a drug that produced the desired effects and compel the user to actively seek more. The downfall of the project had been the fact that an unknown impurity in the batch. Unable to discern the impurity that had made the drug so efficient and, Nathan had no choice but to abandon the project, settling for selling a less efficient strain. 

Warehouses were burnt down. A hit list of all the chemists involved in the creation of the drug was compiled. The only evidence left was the test subjects themselves. Anyone involved in the testing would have to be eliminated. Hundreds upon hundreds of names were compiled in the list, a number and a date by each. Dated 11.21.94 were seven names that Kaz recognized. Bishop Clark - 14. Sarah Hendriks -17. Inna Bethesda - 16. Roy Sanders - 16. Meena Reyes - 19. And finally, Jordan & Kasimir Rietveld - 10 & 6. 

[babytoro]

hey here’s a sneak peak of my fic

multiple actually

here’s two ‘scenes’:

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When I look at Bob now, it’s hard to believe that only nine months ago we were breaking into abandoned houses and getting high on drugs together. Bob used to be a greaser, and he was a pretty loyal one, too. He would spit at the Socs when he passed by them on the street and keep his trap shut when we told him secrets and would snuggle with Ray on the couch when they were watching horror movies together, because Ray’s terrified of horror movies and being held while he’s watching them calms his nerves. I remember how me, him and Toro would always hang out together at the diner and would flirt with the male waiters to embarrass them and then we would laugh whenever one of them went along with it and flirted back at us. I remember how Bob would follow Ray into the forest and would collect flowers with him and wouldn’t think Ray’s fascination with flowers was weird and gay like he does now. I remember when Bob and Frank would wrestle in the middle of my living room because they were that close. But now that’s all just a memory that’s better off being forgotten, because that Bob is gone now, and he’s been replaced with this fat ginger bitch who’s name is used as an insult in the greaser world.

Bob’s father would buy a lottery ticket every Saturday and would literally pray that he would win the jackpot. The Bryars were one of the poorest families in New Jersey, and they could barely afford to eat one piece of bread a day. I actually kind of hoped that they would win the jackpot, just so they were able to eat a healthy amount of food and be able to afford their monthly rent without working three jobs at once. One July morning in the summer of 1985, he came running into my house with this huge grin on his face and started screaming about how his family had just won however many million dollars. Back then, I was ecstatically happy for him and his family. They could fix up their house and they could quit their extra jobs and they could eat something besides stale bread for dinner. Bob had even said that even though he now had the money of a Soc, he still wanted to be in our greaser gang. But after a few weeks had passed, we started to notice a huge change in everything Bob used to be. His clothing style, his personality, the words he used when he talked.. everything changed. He started wearing those expensive cashmere jackets and drove an expensive Aston Martin and would act like he was fucking royalty because of how much money he had. He would get invited to parties and would hook up with hot Soc girls and would go to a random greaser’s house and egg it, because he was rich and they were poor and that somehow made it okay.

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There’s only one person in Belleville who has a voice that annoying. Frank Iero.

I don’t like Frank all too much. He’s annoying as fuck and thinks tackling people to the ground is just a normal thing friends like to do. If I could, I would send Frank off to someplace far from New Jersey just so I wouldn’t have to hear him screaming from down the street because he saw someone walking a dog and wanted to pet it. I mean, I can hear him from down the street. He yells that fucking loud. It’s even better when he’s yelling like that inside my house. But because Gerard and Frank are best friends, I’m forced to put up with him. Gerard would hit me with a belt if I ever slapped Frank to get him to shut up. If Gerard weren’t around I probably would’ve shoved Frank in front of a moving car by now, to be honest.

[stocksnewsfeed]

Alnylam Presents New Evidence Demonstrating Significant Association of V122I, a Highly Prevalent, Pathogenic Transthyretin (TTR) Mutation, with Clinical Diagnosis of Polyneuropathy

CAMBRIDGE, Mass.–(BUSINESS WIRE)–Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today presented new results from an analysis of the UK Biobank – a prospective cohort study with genetic, physical, and health data on approximately 500,000 individuals across the United Kingdom – demonstrating a significant association of the V122I mutation, a highly prevalent mutation in the transthyretin (TTR) gene, with a clinical diagnosis of polyneuropathy. These results were presented at the Heart Failure Society of America (HFSA) 23rd Annual Scientific Meeting being held September 13-16, in Philadelphia, PA.

“The data we and collaborators presented at HFSA indicate that carriers of V122I – a TTR mutation previously thought to be associated with a phenotype presenting primarily with cardiac manifestations – have a significantly increased likelihood of a clinical diagnosis of polyneuropathy,” said Eric Green, Senior Vice President and General Manager, TTR Program at Alnylam. “These findings demonstrate an association of V122I with the presence of a mixed clinical phenotype, supporting the need for a broader assessment of a patient’s overall health to look for multisystem manifestations of hereditary ATTR amyloidosis, which often include both cardiomyopathy and polyneuropathy.”

The V122I variant is the most common pathogenic TTR mutation implicated in hereditary ATTR (hATTR) amyloidosis in the U.S., with a reported prevalence of approximately four percent in African Americans1. Historically, the V122I variant has been associated with a predominantly cardiac phenotype. We presented findings from a phenome-wide association study demonstrating a significant association of the TTR V122I genotype with a clinical diagnosis of polyneuropathy (based on International Classification of Diseases, 10th revision [ICD10] diagnosis codes) in the black subpopulation of the UK Biobank. Among the 6,063 unrelated black participants, 243 subjects (mean age of 52.6 years) were carriers of the TTR V122I mutation, equating to an allele frequency of two percent. Among the carriers, polyneuropathy was significantly associated with the V122I genotype (odds ratio [OR] equals 11.2; 95% confidence interval [CI]; p equals 1.1×10–6). The significant association of V122I with polyneuropathy was further replicated in the Penn Medicine Biobank from 5,737 black participants with 190 subjects who were V122I carriers.

In addition, there was nominally significant evidence that carriers of V122I were at an increased risk for other signs and symptoms of hATTR amyloidosis, including carpal tunnel syndrome and urinary retention. There was no association of V122I with cardiomyopathy, potentially due to the younger age of the carriers in the UK Biobank at the time of analysis (mean age of 52.6 years) as compared to the age at which hATTR amyloidosis with cardiomyopathy typically presents (over 65 years in the V122I population, as reported in the literature2).

Other presentations at HFSA include:

Identifying Mixed Phenotype: Evaluating the Presence of Polyneuropathy in Patients with Hereditary Transthyretin-Mediated Amyloidosis with Cardiomyopathy Lead Author: Grogan M Date/Time: Saturday, September 14, 2019 at 6:15 pm ET.

Risk Factors for Mortality in Patients with Hereditary Transthyretin-Mediated Amyloidosis: Analysis of APOLLO and Global Open Label Extension Studies Lead Author: Polydefkis M Date/Time: Saturday, September 14, 2019 at 6:15 pm ET.

Impact of Patisiran, an RNAi Therapeutic, on Orthostatic Intolerance in Patients with Hereditary Transthyretin-Mediated Amyloidosis Lead Author: Judge DP Date/Time: Friday, September 13, 2019 at 6:15 pm ET.

Alnylam Act®: Heterogenous Disease Manifestations of Hereditary Transthyretin-Mediated Amyloidosis Lead Author: Malladi R Date/Time: Friday, September 13, 2019 at 6:15 pm ET.

To view these results presented at HFSA please visit www.alnylam.com/capella.

Alnylam will host an RNAi Roundtable to discuss the latest progress with its TTR programs on Monday, September 16, at 1:00 pm ET. This event will be webcast live on the Investors page of the Company’s website, www.alnylam.com, and a replay will be posted on the Alnylam website approximately three hours after the event.

Dhamarajan et al. J Am Geriatr Soc 2012;60:765-74.

Ruberg and Berk, Circulation 2012;126:1286-1300.

About Transthyretin (ATTR) Amyloidosis Transthyretin amyloidosis (ATTR) amyloidosis is a rare, serious, life-threatening, multisystemic disease encompassing hereditary ATTR (hATTR) amyloidosis and wild-type ATTR (wtATTR) amyloidosis, which result from either hereditary (genetic mutation) or nonhereditary (ageing) causes, respectively. In ATTR amyloidosis, misfolded TTR proteins accumulate as amyloid fibrils in multiple organs and tissue types. hATTR amyloidosis can include sensory and motor, autonomic and cardiac symptoms and is estimated to impact 50,000 people worldwide. wtATTR amyloidosis predominantly manifests as cardiomyopathy and heart failure symptoms, although patients may experience other manifestations due to extra-cardiac amyloid deposition. The disease is estimated to impact 200,000 – 300,000 people worldwide.

About RNAi RNAi (RNA interference) is a natural cellular process of gene silencing that represents one of the most promising and rapidly advancing frontiers in biology and drug development today. Its discovery has been heralded as “a major scientific breakthrough that happens once every decade or so,” and was recognized with the award of the 2006 Nobel Prize for Physiology or Medicine. By harnessing the natural biological process of RNAi occurring in our cells, a new class of medicines, known as RNAi therapeutics, is now a reality. Small interfering RNA (siRNA), the molecules that mediate RNAi and comprise Alnylam’s RNAi therapeutic platform, function upstream of today’s medicines by potently silencing messenger RNA (mRNA) – the genetic precursors – that encode for disease-causing proteins, thus preventing them from being made. This is a revolutionary approach with the potential to transform the care of patients with genetic and other diseases.

About Alnylam Pharmaceuticals Alnylam (Nasdaq: ALNY) is leading the translation of RNA interference (RNAi) into a new class of innovative medicines with the potential to transform the lives of people afflicted with rare genetic, cardio-metabolic, hepatic infectious, and central nervous system/ocular diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach for the treatment of diseases with high unmet need. Alnylam’s first commercial RNAi therapeutic is ONPATTRO® (patisiran), approved in the U.S., EU, Canada, and Japan. Alnylam has a deep pipeline of investigational medicines, including five product candidates in Phase 3 studies and one in registration. Looking forward, Alnylam will continue to execute on its “Alnylam 2020” strategy of building a multi-product, commercial-stage biopharmaceutical company with a sustainable pipeline of RNAi-based medicines to address the needs of patients who have limited or inadequate treatment options. Headquartered in Cambridge, MA, Alnylam employs over 1,200 people worldwide. For more information about our people, science and pipeline, please visit www.alnylam.com and engage with us on Twitter at @Alnylam or on LinkedIn.

Alnylam Forward Looking Statements Various statements in this release concerning Alnylam’s future expectations, plans and prospects, including, without limitation, expectations regarding the implications of data indicating that carriers of the TTR mutation V122I have a significantly increased likelihood of a clinical diagnosis of polyneuropathy, including the need for a broader assessment of a patient’s overall health to look for the multisystem manifestations of hereditary ATTR amyloidosis, and expectations regarding its “Alnylam 2020” guidance for the advancement and commercialization of RNAi therapeutics, constitute forward-looking statements for the purposes of the safe harbor provisions under The Private Securities Litigation Reform Act of 1995. Actual results and future plans may differ materially from those indicated by these forward-looking statements as a result of various important risks, uncertainties and other factors, including, without limitation, Alnylam’s ability to discover and develop novel drug candidates and delivery approaches, successfully demonstrate the efficacy and safety of its product candidates, the pre-clinical and clinical results for its product candidates, which may not be replicated or continue to occur in other subjects or in additional studies or otherwise support further development of product candidates for a specified indication or at all, actions or advice of regulatory agencies, which may affect the design, initiation, timing, continuation and/or progress of clinical trials or result in the need for additional pre-clinical and/or clinical testing, delays, interruptions or failures in the manufacture and supply of its product candidates, obtaining, maintaining and protecting intellectual property, Alnylam’s ability to enforce its intellectual property rights against third parties and defend its patent portfolio against challenges from third parties, obtaining and maintaining regulatory approval, pricing and reimbursement for products, progress in establishing a commercial and ex-United States infrastructure, successfully launching, marketing and selling its approved products globally, Alnylam’s ability to successfully expand the indication for ONPATTRO in the future, competition from others using technology similar to Alnylam’s and others developing or marketing products for similar uses, Alnylam’s ability to manage its growth and operating expenses, obtain additional funding to support its business activities, and establish and maintain strategic business alliances and new business initiatives, Alnylam’s dependence on third parties for development, manufacture and distribution of products, the outcome of litigation, the risk of government investigations, and unexpected expenditures, as well as those risks more fully discussed in the “Risk Factors” filed with Alnylam’s most recent Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission (SEC) and in other filings that Alnylam makes with the SEC. In addition, any forward-looking statements represent Alnylam’s views only as of today and should not be relied upon as representing its views as of any subsequent date. Alnylam explicitly disclaims any obligation, except to the extent required by law, to update any forward-looking statements.

The post Alnylam Presents New Evidence Demonstrating Significant Association of V122I, a Highly Prevalent, Pathogenic Transthyretin (TTR) Mutation, with Clinical Diagnosis of Polyneuropathy appeared on Stocks News Feed.

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[soorasaab]

Customers who need to replace their fourth generation iPad will now get a newer and more capable iPad Air 2 as a substitute from Apple Stores and authorised service providers, a media report said.

Apple is doing this because the company has no stock left of the ageing and now discontinued fourth generation iPad, 9to5Mac website reported on Saturday.

Apple has also asked its staff to inform customers of the replacement unit's colour and capacity.

The iPad Air 2 introduced a new gold colour option, and has 32GB and 128GB storage options while 16GB and 64GB models were discontinued.

For that reason, the users may receive a slight upgrade in storage when getting a replacement in addition to the device's newer and more powerful internals overall.

The iPad Air 2 was launched back in 2014 as a replacement for the fourth generation iPad, which was discontinued in October the same year.

Weighing in at 437 grams, the iPad Air 2 was powered by the Apple A8X SoC, and said to deliver up to 10-hour battery life. iPad Air 2 also came with an improved 8-megapixel camera. iPad Air 2 offered faster connectivity with 802.11ac Wi-Fi with Multiple-In-Multiple-Out (MIMO) technology.

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