#901 module

[shibachangtimes-blog]

Casio G-Shock DW-5600B-2V (blue) with Module 901 Japan H Digital Watch 1987-1996

[subsequentibis]

what do you MEAN dogwalker is ranked #901 out of 1009 on tmbw..... you dont like dogwalker? woof woof?

but seriously i love the groovy instrumentals with that weird as fuck vocal modulation, plus the like metal sheet wobbling noise that pops up here and there? genius. far from unlistenable.

[ao3feed-destiel-02]

Beneath the Code

read it on AO3 at https://ift.tt/Q152EJy by feedingtheforsaken Dean Winchester is done with the world. After his last mission as a Navy SEAL went horribly wrong, he’s living off the map, far from everything trying to forget — in a jungle village, where no one can find him. But when an off the books robotic super soldier’s program called the ANGELS launches an attack on his village during their test trail, Dean’s quiet life is shattered as he becomes an unwilling witness to a massacre. The robots were never meant to be seen, and they can’t afford any survivors. One of the machines, CASTIEL, is different then the rest after his control module becomes dislodged in the landing, and for the first time, CASTIEL starts thinking for himself as he tries to navigate the jungle with a fractured sense of humanity and ends up saving the very person he’s supposed to kill. Forced into an uneasy alliance, Dean hates everything about him, but they have no choice but to work together to survive. As the secrets behind the ANGELS program unravel and the body count rises, Dean and CASTIEL’s unlikely partnership slowly shifts from distrust to something neither of them expected. Words: 901, Chapters: 1/?, Language: English Fandoms: Supernatural (TV 2005) Rating: Explicit Warnings: Graphic Depictions Of Violence, Major Character Death Categories: F/F, F/M, M/M Characters: Dean Winchester, Castiel (Supernatural), Sam Winchester, Charlie Bradbury, Zachariah (Supernatural), Uriel (Supernatural), Gadreel (Supernatural), Metatron (Supernatural), Anna Milton, Garth Fitzgerald IV, Jessica Moore (Supernatural), Gilda (Supernatural), Bela Talbot, Theo (Supernatural: Holy Terror), Bartholomew (Supernatural), Virgil (Supernatural), Naomi (Supernatural), Bobby Singer (Supernatural), Ellen Harvelle Relationships: Castiel/Dean Winchester, Jessica Moore/Sam Winchester, Charlie Bradbury/Gilda, Ellen Harvelle/Bobby Singer Additional Tags: Alternate Universe, Angst, Dead Dove: Do Not Eat, Slow Burn, plot so much plot, The Author Regrets Nothing, Enemies to Lovers, Except its a one sided hate, Trust Issues, Blood and Gore, sam and dean aren’t related, Alternate Universe - Military, Super Soldiers, castiel is a super soldier, Angels are humans, Government Conspiracy, Castiel Does Not Understand Humans (Supernatural), Slow Build, Explicit Sexual Content, Eventual Smut, Dubious Consent, Forced Alliance, First Time, the slowest of burns, graphic military violence, this is not a nice story, Hurt Dean, Major character death - Freeform read it on AO3 at https://ift.tt/Q152EJy

[spacenutspod]

This week, China will launch three taikonauts to the Tiangong space station. SpaceX’s Falcon 9 has three flights scheduled, with its third Bandwagon rideshare mission followed by two more Starlink missions, all heading to low-Earth orbit. Firefly Aerospace is also rolling Alpha back to the pad for another attempt to launch Lockheed Martin’s LM400 demonstration mission during the weekend. The week’s launch manifest began in the early hours of Monday morning with a Falcon 9 lofting the CRS-32 cargo resupply mission to the International Space Station. Cargo Dragon C209 is due to dock at the Harmony port of the ISS on Tuesday, April 22, at 8:20 AM EDT (12:20 UTC), following a 28-hour coast and rendezvous. Falcon 9 | Bandwagon-3 SpaceX will launch its third Bandwagon rideshare mission on Monday, April 21, at 8:48 PM EDT (00:48 UTC on April 22) from Space Launch Complex 40 (SLC-40) at the Cape Canaveral Space Force Station in Florida. SpaceX’s Bandwagon missions are a series of small satellite rideshare missions that launch payloads into mid-inclination low-Earth orbits (LEO). These missions complement the company’s Transporter missions, which primarily target Sun-synchronous orbits. Payloads are attached to a ring-shaped adapter on the upper stage, known as the Evolved Expendable Launch Vehicle Secondary Payload Adapter (ESPA). These rideshare missions offer customers a 50 kg satellite limit per mounting port for a base price of $300,000, which also helps to manage the mass distribution across the adapter. SpaceX offers flexible pricing for additional mass and, with extenders, significantly larger payloads can also be carried, such as the Haven-Demo at approximately 500 kg. Vast confirmed the intention to launch its technology demonstrator aboard this mission in February during NSF’s visit to its Long Beach factory. It will test key systems such as propulsion, avionics, and communications, but does not contain any pressurized modules. SpaceX has confirmed that Atmos Space Cargo’s prototype reentry capsule, Phoenix-1, will also ride aboard this mission. The capsule will complete two orbits before deploying an innovative inflatable heat shield for atmospheric reentry, decelerating the capsule from orbital speeds to a controlled landing on water without the need for parachutes. The mission will collect critical data that will be used to refine future iterations of the capsule. While this version of Phoenix is capable of transporting up to 100 kg, future versions will be able to carry several tonnes, including rocket stages, according to the company. This inaugural mission will carry four biological and technological demonstrations for three clients. As of the end of 2024, Atmos had already secured a commercial contract for seven reentry missions through 2027. The official payload list has yet to be released, but two weather monitoring satellites from Tomorrow.io and a twelfth cluster of Earth observation satellites from HawkEye 360 are also expected to be onboard. The first Bandwagon mission carried nine payloads to LEO on April 7, 2024. With this latest flight, Bandwagon missions will have launched from each of SpaceX’s three active launch sites on the east and west coasts of the United States. A fourth Bandwagon mission is currently slated for this summer. Phoenix-1 reentry capsule diagram. (Credit: Atmos Space Cargo) Booster B1090 will be supporting this mission on its third flight and will return to the Cape to land on the concrete pad at Landing Zone 2 (LZ-2), just over nine kilometers south of SLC-40. This booster made its debut last December with the 03b mPower 7 & 8 mission, and went on to loft Crew-10 to the International Space Station in March. Chang Zheng 2F/G | Shenzhou 20 China will launch its 15th crewed mission from Site 901 at the Jiuquan Satellite Launch Centre on Thursday, April 24, at 09:17 UTC. This will be the ninth crew transportation flight to the Tiangong space station. The three taikonauts aboard this flight were selected in February but are typically not officially named until around a day before flight. They will relieve the Shenzhou 19 crew of Song Lingdong, Cai Xuzhe and Wang Haoze. The three will return to Earth shortly after an official handover ceremony, having spent six months aboard the station. To date, China has launched 24 taikonauts into orbit, with Jing Haipeng having visited space a record four times. Chang Zheng 2F/G Y20 is rolled to the pad at the Jiuquan Satellite Launch Center. (Credit: CCTV) The Chang Zheng 2F/G (CZ-2F/G) is currently China’s only crew-rated rocket. The Y20 vehicle has been rolled to its launch pad to conduct pre-flight testing. Tiangong has already been maneuvered to the proper position for the Shenzhou 20 craft to dock. Falcon 9 | Starlink Group 6-74 SpaceX is set to loft another batch of satellites into the largest shell of its Starlink constellation. Despite what the numbering may suggest, this will be the 75th launch into the group. Falcon 9 will launch from SLC-40 at the Cape Canaveral Space Force Station in Florida on Thursday, April 24, at 9:32 PM EDT (01:32 UTC on April 25), heading southeast over the Atlantic Ocean. Following deployment, this batch of satellites will move into an operational orbit at 559 km, inclined 43 degrees. The booster supporting this mission has not been confirmed, but is expected to land on an autonomous droneship downrange in the Atlantic Ocean approximately eight minutes into the mission. Falcon 9 | Starlink Group 11-9 The second Starlink mission of the week will launch from Space Launch Complex 4 East (SLC-4E) at the Vandenberg Space Force Base in California on Friday, April 26, at 2:40 PM PDT (21:40 UTC). The flight will carry another batch of Starlink v2-Mini satellites into LEO, taking a southeasterly trajectory during ascent. Starlink connects more than five million people with high-speed internet across 125 countries and territories. The service added Jordan and Guyana to its service list earlier this month and supported video calling during the recent Fram2 crewed mission. The booster supporting this mission has not been confirmed, but is expected to land on the west coast droneship, Of Course I Still Love You, which will be stationed downrange in the Pacific. Alpha | Message In A Booster Firefly Aerospace will attempt to launch a technological demonstration of Lockheed Martin’s new LM400 satellite bus on Sunday, April 27. Previous attempts were postponed due to unspecified range conflicts. The mission will launch from Space Launch Complex-2W (SLC-2W) at the Vandenberg Space Force Base in California at 6:37 AM PDT (13:37 UTC). This flight will be the sixth launch of an Alpha rocket and marks the second of up to 25 flights for Lockheed Martin as part of a multi-launch agreement with Firefly, which will span the next five years. Lockheed Martin’s versatile new mid-sized satellite bus can accommodate a variety of missions, including remote sensing, communications, imaging, and radar operations. The LM400 Pathfinder will help prove the technology in orbit and contribute towards risk reduction before flying customer missions. While this demonstrator will be deployed to LEO, the platform is adaptable to multiple orbits and launch configurations, catering to military, civil, and commercial applications. Render of the Lockheed Martin LM400 tech demonstration (Credit Lockheed Martin) The two-stage expendable Alpha vehicle stands just under 30 m in height and can deliver 1,030 kg to LEO. Four Reaver engines on the first stage burn liquid kerosene and oxygen in a tap-off cycle, while a single Lightning engine using the same technology powers the upper stage. NASASpaceflight is providing launch live stream production services for Firefly Flight A006. Atlas V 551 | Project Kuiper (KA-01) United Launch Alliance’s (ULA) Atlas V is set to launch the first batch of 27 operational communication satellites for Amazon’s Kuiper constellation to LEO. Amazon plans to deploy 3,236 satellites into this constellation, providing global broadband internet coverage. The satellites will operate in 98 orbital planes across three layers at altitudes of 590, 610, and 630 km — higher than its rival, Starlink. Atlas V 551 on the pad during the previous launch attempt (Credit: ULA) Atlas V will launch in its most powerful 551 configuration, supported by five solid rocket boosters. Liftoff is scheduled for Monday, April 28, at 7:00 PM EDT (23:00 UTC) from Space Launch Complex 41 (SLC-41) at the Cape Canaveral Space Force Station in Florida, during a two-hour launch window. The previous attempt was postponed in early April due to unfavorable weather conditions. The launch also marks the 250th flight of a Centaur upper stage atop an Atlas rocket, and its 275th overall. ULA has contracts for up to 83 Kuiper launches, with seven additional missions to be flown aboard Atlas V 551 rockets. The remaining missions will fly on Atlas V’s successor, Vulcan Centaur. Kuiper satellites are also set to fly on New Glenn and Falcon 9. (Lead image: Falcon 9 launches to orbit. Credit: Julia Bergeron for NSF ) The post Launch Roundup: China to launch crew, Falcon 9 to launch Bandwagon rideshare appeared first on NASASpaceFlight.com.

[brookstonalmanac]

Events 11.28 (after 1920)

1920 – FIDAC (The Interallied Federation of War Veterans Organisations), the first international organization of war veterans is established in Paris, France. 1920 – Irish War of Independence: Kilmichael Ambush: The Irish Republican Army ambush a convoy of British Auxiliaries and kill seventeen. 1925 – The Grand Ole Opry begins broadcasting in Nashville, Tennessee, as the WSM Barn Dance. 1942 – In Boston, Massachusetts, a fire in the Cocoanut Grove nightclub kills 492 people. 1943 – World War II: Tehran Conference: U.S. President Franklin D. Roosevelt, British Prime Minister Winston Churchill and Soviet Premier Joseph Stalin meet in Tehran, Iran, to discuss war strategy. 1958 – Chad, the Republic of the Congo, and Gabon become autonomous republics within the French Community. 1958 – First successful flight of SM-65 Atlas; the first operational intercontinental ballistic missile (ICBM), developed by the United States and the first member of the Atlas rocket family. 1960 – Mauritania becomes independent of France. 1964 – Mariner program: NASA launches the Mariner 4 probe toward Mars. 1964 – Vietnam War: National Security Council members agree to recommend that U.S. President Lyndon B. Johnson adopt a plan for a two-stage escalation of bombing in North Vietnam. 1965 – Vietnam War: In response to U.S. President Lyndon B. Johnson's call for "more flags" in Vietnam, Philippine President-elect Ferdinand Marcos announces he will send troops to help fight in South Vietnam. 1966 – Michel Micombero overthrows the monarchy of Burundi and makes himself the first president. 1967 – The first pulsar (PSR B1919+21, in the constellation of Vulpecula) is discovered by two astronomers Jocelyn Bell Burnell and Antony Hewish. 1971 – Fred Quilt, a leader of the Tsilhqot'in First Nation suffers severe abdominal injuries allegedly caused by Royal Canadian Mounted Police officers; he dies two days later. 1971 – Wasfi al-Tal, Prime Minister of Jordan, is assassinated by the Black September unit of the Palestine Liberation Organization. 1972 – Last executions in Paris: Claude Buffet and Roger Bontems are guillotined at La Santé Prison. 1975 – East Timor declares its independence from Portugal. 1979 – Air New Zealand Flight 901, a DC-10 sightseeing flight over Antarctica, crashes into Mount Erebus, killing all 257 people on board. 1980 – Iran–Iraq War: Operation Morvarid: The bulk of the Iraqi Navy is destroyed by the Iranian Navy in the Persian Gulf. (Commemorated in Iran as Navy Day.) 1983 – Space Shuttle Columbia is launched on STS-9, the first mission to carry the European Space Agency's Spacelab module. 1987 – South African Airways Flight 295 crashes into the Indian Ocean, killing all 159 people on board. 1989 – Cold War: Velvet Revolution: In the face of protests, the Communist Party of Czechoslovakia announces it will give up its monopoly on political power. 1990 – British Prime Minister Margaret Thatcher resigns as leader of the Conservative Party and, therefore, as Prime Minister. She is succeeded in both positions by John Major. 1991 – South Ossetia declares independence from Georgia. 2002 – Suicide bombers blow up an Israeli-owned hotel in Mombasa, Kenya; their colleagues fail in their attempt to bring down Arkia Israel Airlines Flight 582 with surface-to-air missiles. 2014 – Gunmen set off three bombs at the central mosque in the northern Nigerian city of Kano killing at least 120 people. 2016 – LaMia Flight 2933 crashes near Medellin, Colombia, killing 71 of 77 people on board, including members of the Brazilian football club Chapecoense 2020 – Over seven hundred civilians are massacred by the Ethiopian National Defense Force and Eritrean Army in Aksum, Ethiopia.

[kecocontrol]

Rosemount Precision: The Cutting-Edge Rosemount 3051 Pressure Transmitter

https://kecocontrols.com/product/rosemount-3051-pressure-transmitter - Discover the cutting-edge Rosemount 3051 Pressure Transmitter from KECO Controls, engineered for unparalleled precision in measuring pressure and differential pressure. This device features advanced sensor technology and a wide operability range, making it suitable for various mediums including air, gas, liquid, steam, and more. It comes equipped with options like HART digital, 4-20 mA, and low power 1-5 VDC electronic modules, alongside customizable 2-valve or 3-valve Manifolds to cater to specific industrial requirements. Designed for robustness and precision, the transmitter ensures easy installation with factory configuration and calibration tailored to your application. Ideal for a multitude of industries such as power generation, oil and gas, pharmaceuticals, and water treatment, it guarantees efficiency, accuracy, reliability, and safety in every operational environment. Elevate your pressure measurement standards by visiting kecocontrols.com or contacting us for specialized support.

Contact Us: Keco Engineered Controls 1200 River Ave., Bldg 3A Lakewood, NJ 08701-5657 Email: sales@kecocontrols.com Phone: 732-901-5900 Fax: 732-901-5904 https://kecocontrols.com/

[dancingforhealing]

LDT (Lymph Drainage Therapy), Yoga Bandha and Flamenco For Facilitating The Lymph Flow

MLD and proper movements in a therapeutic sequence for promoting the Lymph flow .

This course will present evidence-based data on Lymph Drainage approaches and state-of-the-art techniques, learned and practiced trough a  network with a broad array of colleagues and experts, and share high-yield experiences to help attendees improve their client outcomes.

Interactive Q&A sessions at the end of each module will offer the opportunity to debate the evidence, exchange ideas, and gain invaluable insight to assist with the most challenging cases.

It explores traditional LDT approaches in combination with intrinsic physiological mechanisms and therapeutic movements for assisting /promoting the Lymph system in its adaptive role.

In this class you will learn:

How the lymphatic system works and how you can help improve the health of the patients during and after the cancer treatment

About the PrimoVascular System: unique anatomical system shifting a medical paradigm and its role in Lymphatic system formation and in cancer metastasis

Simple Protocols for Detoxification and Minor Pathologies, adaptable to each patient's specific problem

What happens when pathways of the lymphatic system have been interrupted and how lymphedema develops

How to distinguish primary lymphedema from secondary lymphedema

How to facilitate its drainage by stimulating the preserved lymph flow - "Lymphatic mapping"

Yoga Bandha and specific movements/exercises from various dance forms which will improve the lymph flow from different lymphatic zones in the body

For place and times Contact :

(901) 351-8417

estoeva@comcast.net

In this class you will learn:

How the lymphatic system works and how you can help improve the health of the patients during and after the cancer treatment

About the PrimoVascular System: unique anatomical system shifting a medical paradigm and its role in Lymphatic system formation and in cancer metastasis

Simple Protocols for Detoxification and Minor Pathologies, adaptable to each patient's specific problem

What happens when pathways of the lymphatic system have been interrupted and how lymphedema develops

How to distinguish primary lymphedema from secondary lymphedema

How to facilitate its drainage by stimulating the preserved lymph flow - "Lymphatic mapping"

Yoga Bandha and specific movements/exercises from various dance forms which will improve the lymph flow from different lymphatic zones in the body

[certmagic-itcertification]

How to prepare for the Exam DP-300: Administering Relational Databases on Microsoft Azure!

In this article, we will show how to prepare yourself for the DP-300 exam: Administering Relational Databases on the Microsoft Azure certificate exam.

Exam Overview:

The Administering Relational Databases on the Microsoft Azure certificate exam measures your intermediate-level knowledge in seven main areas. This includes:

How to plan and implement data platform resources, with relative questions weight in the exam up to 20%

How to implement a secure environment, with relative questions weight in the exam up to 20%

How to monitor and optimize operational resources, with relative questions weight in the exam up to 20%

How to optimize query performance, with relative questions weight in the exam up to 10%

How to perform automation of tasks, with relative questions weight in the exam up to 15%

How to plan and implement a High Availability and Disaster Recovery (HADR) environment, with relative questions weight in the exam up to 20%

How to perform administration by using T-SQL, with relative questions weight in the exam up to 15%

Before starting this course, it is recommended to have basic knowledge in:

Operating system and virtualization concepts, such as Virtual Machines, virtual networking, and virtual hard disks

The SQL Server Network configurations, such as TCP/IP, DNS, virtual, VPNs, firewalls, and in-transit encryption

SQL Server database creation, management, and configuration

Performing different administration tasks and querying using T-SQL language

SQL Server table and index types and structures

With no official prerequisites for this exam, it is recommended, but not mandatory, to take the Microsoft Azure Fundamentals (AZ-900) exam if you are very new to Microsoft Azure world, and take the Microsoft Azure Data Fundamentals (DP-900) if you are new to all Microsoft Azure data platform.

You can easily schedule the exam from the Administering Relational Databases on the Microsoft Azure certificate page.

Study Guideline:

In order to prepare yourself for the Administering Relational Databases on Microsoft Azure exam, you can go through this comprehensive book Administering Relational Databases on Microsoft Azure, in which you can find detailed information about each required skill and practice tests to measure your skills before the exam, or you can go through the 7-module Administering Relational Databases on Microsoft Azure Learning Path self-study course provided by Microsoft that helps you in getting the basic knowledge required to pass that exam.

If you are not interested in reading the pages and prefer to listen, you can subscribe to any online course such as CertMagic or any other training provided by training sites and centres.

Take into consideration that this exam contains a large number of subjects. In order to pass the exam, you need to have enough knowledge in each subject, without going very deep in each subject. For me, I prefer to be fully prepared for the certificates exams and gain all the required knowledge in order to be able to provide training in the courses I am certified in and apply these skills in my customers’ sites. So, I will list all measured skills in this course and the official resource to study that subject.

For More Detail Visit: https://www.certmagic.com/exam/mb-901-exams

[liketolaugh-writes]

Skeletons Rattle in the Dark

Author: liketolaugh Summary: The doll was stained in blood both red and blue; decades of wear had faded much of the color from its surface. To anyone else, it was unsettling, even scary, cursed or haunted. But Connor, falling apart under the weight of sins both his and not, couldn’t bring himself to put it down for more than a few minutes at a time.

After Markus made his speech to the crowd of newly-freed androids, Connor slipped away into a corner where he can hide until night fell.

It wasn’t the final straw, what Amanda had done. In some ways it had felt like karma, or catharsis, like a horror he had earned and deserved even as he fought it so desperately – so it didn’t hurt as much as Connor felt it should have (though it hurt quite a lot.) Actually, Connor would be hard-pressed to say what had been the final straw, the event that pushed him past the point of tolerance into a keening void of black emotion.

Was it when Lieutenant Anderson had held a gun to his head and asked him if he was afraid to die, and Connor had said no because that was the answer Amanda would have wanted?

Was it the third death, when the task of crawling across the floor had seemed insurmountable and he just closed his eyes to wait?

Was it when Elijah Kamski had pushed a gun into his hands and whispered for him to destroy the machine in front of him, and he had obeyed despite the ringing emptiness of death that echoed behind his eyes?

Was it when he looked Markus in the eyes and finally allowed himself to understand that everything he’d worked so hard for was wrong?

The answer was out of Connor’s reach, and in the end it didn’t matter at all – by the time he opened his eyes on the stage again and put the gun in his pocket, he was drowning and he knew he couldn’t stay. The few hours left of the day passed in a blur, and people passed his hiding place by without a second glance. It wasn’t until long after darkness fell that Connor dared come out, wandering the abandoned streets in numb search of a place to go.

He couldn’t stay here.

Connor walked, and it wasn’t fast enough so he jogged, and then he was running, taking turns at random as if to lose himself in the streets despite the GPS in his HUD that kept careful track of every step he took.

It was close to one edge of the city that he slowed from a run to a jog to a slow, listless walk, feeling no better than when he’d started. His mood got darker with every step, a tired and raw anxiety wrapping around his shoulders. He didn’t trip only because the motion protocols were mindless, calculated in a distant part of his mind, but his walk got slower and slower until he stopped, overwhelmed by the prospect of going a single step further.

He looked down. A few feet in front of him, there was a little doll, clearly old and used – rain-soaked, stained, worn from the years. One of the printed-on eyes had had most of the color rubbed away. A little bottle patterned with flowers sat about six inches away.

It was stained with thirium, like much of the street nearby. If there was a body – a YK model, maybe – that the doll had belonged to, it had been cleared away. Connor let his legs fold to kneel down beside it, hands pressing flat to the ground, and his choking misery threatened to swallow him up again. His body heaved and shivered, his shoulders bent under a nonexistent weight, and for a while he stared silently at the doll. There were brown stains peeking out from the back of it – blood, more likely than not, and very old blood at that.

[2005 Kinder Garden Babies doll, violet]

What was he going to do? Where could he go? Lieutenant Anderson, who looked at him with such disgust, wouldn’t look twice at him – the police department, eying him warily, certainly wouldn’t either. Jericho, which he’d harmed so horribly, would be quite right to cast him out, and the names just piled up – the Tracis, the Chloe, Ralph and Rupert and the HK400 who hadn’t had a name at all-

And now Amanda among them, and Connor was alone.

Before he could think twice about it, his hands scooped up the doll, smaller than a true infant and just big enough to comfortably hold in two hands, and he squeezed it to his chest. His next breath came in a gasp, and he choked on the one after. The third came close to a wheeze.

The fourth wrenched itself up in a sob, and tears, saline cleaning solution, started to spill down his cheeks, with no rain to mask them, only the soft dark of a city night. He clung to the abandoned doll like he’d forgotten how to let go, like if he did he’d lose himself and fall, and it didn’t matter if it was true because he wasn’t letting go. He stayed in place and rocked himself and cried, wept and sobbed and surrendered to the tempest that had dragged at him for days.

Connor stayed there until the light of dawn started to lighten the sky above, and while the tears had stopped by then the shaking hadn’t, nor had he loosened from his tightly curled posture, wrapped around the doll in search of comfort he didn’t deserve and no one else would provide.

But with the dawn would come the first stirrings of civilization, calmed down for only a night by the terror of the revolution, and Connor couldn’t stay.

He took the doll with him. Tucked her bottle into his pocket and her body against his chest, and walked away, hurried but not frantic, not desperate. The one to whom she had previously belonged had no need of her anymore (YK500 #548 901 257, designation: Sadie) and he couldn’t bring himself to put her down. It was silly, it was irrational, but he felt so lost and having something to hold, to stroke and neaten, helped ground him.

Connor held on only long enough to make his way into a condemned parking garage, to find an alcove to tuck himself into and set the doll in his lap, and he pushed himself into stasis because he suddenly found he couldn’t stand to be awake for one moment longer.

He dreamed of falling, not from a fifty story building but into an abyss that never ended, knowing that he wouldn’t be alive to feel himself hit the ground.

------------

“I know that my memory ends before I truly die,” Connor murmured to the doll, to Venus in her little stained purple outfit emblazoned with a brand name that had long become too worn to read. “But I cannot help but feel like the silence between upload and reactivation is too… dense. There is no life after death, Venus, at least not for androids. There’s nothing but emptiness waiting for us.”

He had shifted locations three times in the last week, not wanting to stay in one place more than a few days. No one would look for him, except perhaps to kill him in vengeance, but he did not want to invoke curiosity by becoming a staple anywhere either. He had taken Venus with him every time, her bottle in the crook of her arm or in his pocket, and her face tucked against his chest.

She appeared to have no mechanical parts, but despite this hindrance she often moved in the night and sometimes when he simply turned around for a few moments. Connor found he didn’t mind. That was, apparently, just Venus’ nature.

Connor exhaled, letting his forehead fall against that of the little doll and his eyes close. “Is that what I sentenced Chloe to, Venus? Did I sentence her to a null eternity?” He huffed softly. “I suppose that’s a contradiction, of sorts, but I can’t bring myself to abandon the thought. Or did Kamski reupload her? Perhaps she dreams of the emptiness too.”

The blood staining her clothing had been rubbed and worn beyond crunching under his touch like a near-fresh stain, and testing had not revealed any known DNA profile. Likely she was too old for that. Her ‘model’ was, after all, thirty-three years old. The bloodstains probably predated androids as a people, let along Connor himself.

There are no dreams, Connor. There is only… the imprint of your own memories.

Venus’ voice came in a whisper, barely on the edge of even Connor’s exceptional hearing, and he found that this didn’t bother him either. Not only was it not the first time he’d heard a voice attributable to Venus, but he simply… didn’t have the energy to mind.

Venus was the only one he’d spoken to in the last week, and the only one he planned to speak to for a very long time yet.

“I know,” he whispered against her forehead. “I know.”

Shh. It’s okay to cry. I won’t tell.

Connor did, not the wracking sobs of the first night but silent and trailing tears.

“Lieutenant Anderson wanted to send me there,” he breathed through the static rasp of his vocal module. “I can’t help but think that he knew. I deserve it now, and I deserved it even more then, but it still feels… Lieutenant Anderson and I are not friends, but I still can’t bring myself to reconcile that night with his behavior at large.” Pause. “Perhaps he thinks of it as a relief. He wants so badly to go there himself.”

A few moments of silence, and Connor breathed, deep and shuddering, leaning on the concrete wall blocking off the roof’s edge, under the cover of the witching hour.

Eventually, he lifted his head, and released Venus with one hand to wipe the tears away from his face. His Cyberlife jacket was long gone, replaced by a hoodie he’d scrounged up from somewhere, too big and unmarked. His LED blinked miserable yellow, in plain sight.

Some people do, Venus whispered. Coleen did. Now I make other people want to, like her family made her.

“I suppose I couldn’t hurt anybody there,” Connor murmured, unfocused eyes gazing down at Venus’, which stared back up at him, blank and worn pale, lips pursed in the faintest of innocent smiles. “That would be a relief all on its own. I would never hurt anybody ever again.” He hesitated, but this was Venus, and if he didn’t speak the thought would swallow him. “And nobody could hurt me.”

Not you, Venus said, breathy and soft. You’re not like them. You’re a cursed doll, like me.

“Oh,” Connor breathed, and he pulled Venus to his chest, cradled careful and kind. “That’s alright then.”

His tired gaze stared out over the city from the parking garage rooftop where he stood. He found he wasn’t as frightened of heights as he had been once.

-------------

Connor washed Venus eventually, as gentle as his well-calibrated hands could manage, soap and water in a public bathroom. The very oldest stains, the old blood soaked into her back, didn’t wash away, but years of dirt and dust turned the water grey and swirled down the drain. It didn’t brighten her outfit to a new color, but it was a faded pastel lavender that Connor had learned to find more comforting than almost anything else in the world.

He patted her dry with the paper towels, ignored the humans that edged around him, and sighed softly when not all of the moisture came up so easily.

“I could set you in the sun for a while,” Connor murmured, lifting her and setting her in the crook of his elbow, body half turned in to his. He set the bottle against her wrist and it did not fall, and then straightened her crooked cap. “That would likely dry away the last of the moisture before you mildewed; the sun is bright today.”

Venus did not reply, but Connor nodded anyway, stepping outside and slipping away from the slight crowds and into darker, more remote alleyways with all the haste he could manage.

He’d been on his own for months now; spring was in full swing, and much of the rain had petered off, along with almost all of the snow. That was much of why he had chosen to wash Venus today – the weather was near-optimal for helping her dry.

“I could have waited until summer, and this part would have been easier,” he said to her, quiet, “but then you would have been dirty for much longer, and I’m certain that can’t be pleasant.”

He’d found a decommissioned ship to stay in for that week, not too terribly far from where Jericho had been, but not so close that it seemed disrespectful either. Finding places to stay had become easier as the habit developed, and soon he would be able to reuse old locations without arousing fresh suspicion.

Connor still avoided people as much as he could – androids more than humans, but humans still as much as he feasibly could. He felt- anxious, unwelcome, wary around others.

Fortunately, others felt wary around him as well. Or more specifically, around Venus.

He found a sunny spot within the rusty ship and Venus down carefully. “There. That should do.”

Thank you, Venus breathed. I haven’t been clean in so long.

Connor smiled faintly, reaching out to brush his fingers over the violet cap. “Of course. It’s the very least I could do.” He tilted his head back, looking at the sky. “I’ve never seen a spring before. It’s… nice, to see the flowers bloom.” He swallowed. “Except the roses. I don’t know why, but the roses make me feel ill.” He glanced at Venus. “I’m an android. I don’t get ill.”

I have seen many springs, Venus whispered to him. They always bring a new year.

“I don’t need a new year,” Connor said before he could think better of it. “All I need is… is this. I’m okay if it stays like this forever.” The thought of before made his breath catch, and the thought of what may lay ahead made him shiver.

You’ll get one anyway, Venus said. But you can make it the same if you want.

“I do,” Connor said fervently. “I’d mess up anything else I tried. I always have.”

Venus did not reply, and Connor fell silent, hunched down on himself again, and watched the progress of evaporating moisture instead. He already wanted to pick up and hold Venus again, but he wanted to make sure she dried properly first.

He didn’t want her to wear down any more than he could prevent. He didn’t know what he’d do if she fell apart.

----------

Between his own capabilities and Venus’ own, Connor made it clear from November to June before encountering anyone he knew. But Markus, it turned out, was made of stronger stuff than that.

Connor woke up to rabbit heartbeat pounding in his chest, eyes already wide before he understood what was happening; a stranger had entered the condemned apartment complex where he’d spent the last week, and as he sat up, he met their eyes.

Markus stared back, rigid and understandably wary, but standing steady in his place with his hand clenched tight around the doorframe.

Connor pushed himself carefully back, just half a foot, without pausing to think about it. He couldn’t bring himself to speak. His hand found Venus, always within easy reach, and he pulled her tight against himself, internal ventilation kicking up a notch as if already threatening to overheat. He didn’t stand.

Markus’ eyes flicked briefly to the doll, and then settled on Connor again, noticeably dimmer, as if sad despite the tension that still wracked his frame.

“Connor,” Markus said, soft and gentle, the way one spoke to an injured animal. And then, impossibly, he smiled, more reassuring than happy but a surprise either way. Connor stared at him. “You’re a hard man to find.”

He slid in, slow and easy to follow with no sudden movements, but Connor scooted a little farther away anyway, eyes wide. Markus lowered himself to the ground, crouching but not sitting, and didn’t let his smile fall.

“Lieutenant Anderson has been asking after you,” Markus continued, quiet. “He seems to think you’ll show up in Jericho sooner or later. Whether or not you do is up to you, of course.”

Connor took a breath, short and sharp. The hand still on the ground came up to cradle the back of Venus’ head, holding her tighter against himself, and he knew it made him look a little deranged but he felt slightly deranged, so it was fine.

Markus’ voice became, impossibly, softer. “Your absence has been noted, I should say. Those you brought from Cyberlife Tower, in particular, have missed you. I’m sure they would welcome your company, and perhaps your guidance, should you offer.”

Perhaps involuntarily, Markus’ gaze flickered around the room – the worn walls, the recently rearranged furniture. It was a temporary dwelling, for Connor, and it showed. Markus frowned, and Connor’s rusty social routines said, worry.

“And I have been curious as well,” Markus added. “I know you weren’t yourself as a machine, Connor – no one is. It isn’t fair that you’re being blamed for the sins you couldn’t help.”

Connor shuddered quietly, and spoke for the first time. “It was never about what was fair.”

Markus paused, visibly surprised, and met Connor’s eyes.

“I suppose not,” Markus agreed after a moment. “Still, I’m sorry you had to suffer for it.”

Connor shrugged. Markus hardly knew the whole of it, anyway.

Markus smiled at him, small and strained. “Will you at least consider coming by, Connor? I’d consider it a personal favor – I’ve been worried, I must admit.”

His dual-toned eyes were too intense. He seemed sincere.

Connor hesitated, and then slowly moved to sit cross-legged, set Venus in his lap and looked at her because he couldn’t bear to look at Markus for a moment longer.

“I don’t know if I should,” he murmured to Venus, knowing Markus could hear him but unable to keep himself from speaking anyway. “I’m not welcome in Jericho, nor should I be – my sins as a machine can’t be wiped away by simple time, and they’ll be afraid and they won’t be wrong.” He paused. “But perhaps I can help, if I really try. If they want me to. Don’t I owe them that?”

Venus did not reply; she never did around others. Regardless, Connor knew what her response would be. This was Connor’s choice alone – Venus went where she was taken.

He picked Venus up again, tucked her against his chest behind crossed arms, and looked at Markus, who watched him expectantly, a faint furrow in his brow.

“Did Lieutenant Anderson really ask after me?”

[bearballing]

finished and passed comptia a+ 902 (on the first try lol)

looks at new comptia a+ 1001 first module is about mobiles. lmao how things have changed since 2016, the 901 course had like a few sections on mobile but not a whole ass module

[cmsmartnetbase-blog]

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[operation-ascent-blog]

SPARROW [version 1.01] (c) 2032 OPERATION: ASCENT

C:\Windows\system32>format A: press ENTER when ready . . . INITIALIZING . . .

HOSTNAME: SPARROW V1.01 NEURAL WEB MOUNTED NEURAL WEB . . . SYNCED SENTENCE PARSER . . . SYNCED GRAMMAR ANALYSIS MODULE . . . SYNCED SYNC 100%! INITIALIZING . . .

ERROR CODE 901: NO VISUAL INPUT

[ao3feed-destiel-02]

Beneath the Code

Beneath the Code https://ift.tt/lFp1IJg by feedingtheforsaken Dean Winchester is done with the world. After his last mission as a Navy SEAL went horribly wrong, he’s living off the map, far from everything trying to forget — in a jungle village, where no one can find him. But when an off the books robotic super soldier’s program called the ANGELS launches an attack on his village during their test trail, Dean’s quiet life is shattered as he becomes an unwilling witness to a massacre. The robots were never meant to be seen, and they can’t afford any survivors. One of the machines, CASTIEL, is different then the rest after his control module becomes dislodged in the landing, and for the first time, CASTIEL starts thinking for himself as he tries to navigate the jungle with a fractured sense of humanity and ends up saving the very person he’s supposed to kill. Forced into an uneasy alliance, Dean hates everything about him, but they have no choice but to work together to survive. As the secrets behind the ANGELS program unravel and the body count rises, Dean and CASTIEL’s unlikely partnership slowly shifts from distrust to something neither of them expected. Words: 901, Chapters: 1/?, Language: English Fandoms: Supernatural (TV 2005) Rating: Explicit Warnings: Graphic Depictions Of Violence, Major Character Death Categories: F/F, F/M, M/M Characters: Dean Winchester, Castiel (Supernatural), Sam Winchester, Charlie Bradbury, Zachariah (Supernatural), Uriel (Supernatural), Gadreel (Supernatural), Metatron (Supernatural), Anna Milton, Garth Fitzgerald IV, Jessica Moore (Supernatural), Gilda (Supernatural), Bela Talbot, Theo (Supernatural: Holy Terror), Bartholomew (Supernatural), Virgil (Supernatural), Naomi (Supernatural), Bobby Singer (Supernatural), Ellen Harvelle Relationships: Castiel/Dean Winchester, Jessica Moore/Sam Winchester, Charlie Bradbury/Gilda, Ellen Harvelle/Bobby Singer Additional Tags: Alternate Universe, Angst, Dead Dove: Do Not Eat, Slow Burn, plot so much plot, The Author Regrets Nothing, Enemies to Lovers, Except its a one sided hate, Trust Issues, Blood and Gore, sam and dean aren’t related, Alternate Universe - Military, Super Soldiers, castiel is a super soldier, Angels are humans, Government Conspiracy, Castiel Does Not Understand Humans (Supernatural), Slow Build, Explicit Sexual Content, Eventual Smut, Dubious Consent, Forced Alliance, First Time, the slowest of burns, graphic military violence, this is not a nice story, Hurt Dean, Major character death - Freeform via AO3 works tagged 'Castiel/Dean Winchester' https://ift.tt/msbhVX8 April 28, 2025 at 03:21AM

[oaresearchpaper]

In Silico Inhibition Study of Phytocompounds from Medicinal Plants Against Breast Cancer Proteins

Abstract

Breast cancer is a type of cancer that originates in the cells of the breast tissues. B. pinnatum, C. sieberiana, C. tora and T. indica are the four medicinal plants whose phytochemicals were used for this In silico study. In this study, eight different ligands were evaluated for their interactions with the human epidermal growth factor 2 (HER2) protein (PDB ID: 3pp0). The ligands, including Apigenin, Bryophyllin A, Catechin, Emodin, Islandicin, Quercetin, Sitosterol, and Taxifolin, were assessed based on binding scores and hydrogen bond interactions. Among these ligands, Apigenin exhibited the highest binding score (- 6.5 kcal/mol), indicating its strong binding affinity to the HER2 protein. Bryophyllin A also displayed a significant binding score (- 6.3 kcal/mol) and formed a hydrogen bond with Met 901. Catechin, while having a slightly lower binding score (- 5.9 kcal/mol), engaged in hydrogen bonds with Ser 728, Arg 849, and Asn 850. Emodin, Quercetin, and Taxifolin demonstrated moderate binding scores (- 6.2, – 6.4, and – 6.0 kcal/mol, respectively) and formed hydrogen bonds with Asp 863 and Met 801. Islandicin formed a hydrogen bond with Gly 787 and Leu 786, with a binding score of – 6.1 kcal/mol. Sitosterol exhibited the lowest binding score (- 5.3 kcal/mol) but still established a hydrogen bond with Asp 863 and Met 801. Overall, Apigenin and Bryophyllin A emerged as the most promising ligands due to their strong binding affinities and specific hydrogen bond interactions with HER2. However, experimental validation is essential to confirm these findings and explore their potential as inhibitors or modulators of HER2. Furthermore, all ligands were successfully docked to the active sites of the HER2 protein, indicating their potential relevance in targeting HER2-related pathways. Importantly, the ligands exhibited favorable pharmacokinetic properties with no violations, except for Sitosterol, which showed minor violations in Lipinski, Ghose, Egan, and Muegge’s rules.

Introduction

Breast cancer is a type of cancer that originates in the cells of the breast tissues. It primarily affects women but can also occur in men. It is characterized by the uncontrolled growth of abnormal cells in the breast tissue, forming a lump or mass called a tumor (Dashti et al., 2020). Breast cancer can spread to other parts of the body through the lymphatic system or bloodstream, leading to metastasis (Iqbal and Iqbal, 2014; Pegram and Jackisch, 2023). Early detection and advancements in treatment have significantly improved the prognosis and survival rates for those diagnosed with breast cancer (Pegram and Jackisch, 2023). The exact causes of breast cancer are not fully understood, but several risk factors have been identified. These include genetics (family history of breast cancer or carrying certain mutations like BRCA1 and BRCA2), hormonal factors (early onset of menstruation, late menopause, hormone replacement therapy), age (risk increases with age), certain inherited gene mutations, exposure to ionizing radiation, obesity, alcohol consumption, and more (Sun et al., 2017). While these factors can increase the risk, not everyone with these risk factors will develop breast cancer. Breast cancer can have wide-ranging effects on individuals physically, emotionally, and socially. Physically, it can lead to symptoms such as a lump in the breast, changes in breast size or shape, skin changes, and nipple discharge (Kim, 2021; Sun et al., 2017). Emotionally, the diagnosis can cause anxiety, fear, depression, and uncertainty. Socially, it may impact relationships and daily life. The effects of treatment, including surgery, chemotherapy, radiation, and hormone therapy, can also cause physical and emotional challenges. Treatment for breast cancer depends on the stage and type of cancer, as well as individual factors (Iqbal and Iqbal, 2014; Pegram and Jackisch, 2023). Common treatments include surgery (lumpectomy or mastectomy), radiation therapy, chemotherapy, targeted therapy, hormone therapy, and immunotherapy (Burguin and Diorio, 2021; Moo et al., 2019). Treatment plans may involve a combination of these approaches (Pegram and Jackisch, 2023). The goal is to remove or destroy the cancer cells, prevent recurrence, and improve overall quality of life (Moo et al., 2019). Researchers have identified specific molecular and genetic targets that play a role in the development and growth of breast cancer. Targeted therapies focus on these specific molecules, receptors, and genetic mutations to inhibit cancer growth (Burguin and Diorio, 2021). Some targeted therapies are designed to block hormone receptors (such as estrogen or progesterone receptors), while others target overexpressed proteins like HER2. HER2, or human epidermal growth factor receptor 2, is a protein that plays a role in regulating cell growth and division. In some breast cancers, there is an overexpression or amplification of the HER2 gene, leading to an increased production of the HER2 protein (Hussain et al., 2020; Iqbal and Iqbal, 2014). HER2-positive breast cancer is an important target in breast cancer treatment because the overexpression of HER2 is associated with more aggressive tumor growth and a poorer prognosis (Iqbal and Iqbal, 2014). Targeting HER2 can help slow down the progression of the cancer and improve treatment outcomes. In molecular docking studies, the HER2 (human epidermal growth factor receptor 2)

Source : In Silico Inhibition Study of Phytocompounds from Medicinal Plants Against Breast Cancer Proteins | InformativeBD

[zanothdraws]

19/07/2022 - Course: Designing Dragons with Antonio Stappaerts - Module 2, rotating organic shapes

Practice Duration: 2:05 Total hours of practice: 901:17 Hours left till goal: 9098:43