#Best Multichannel pipette

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Understanding the Different Types of Pipettes and Their Uses

Pipettes are indispensable tools in laboratories worldwide, playing a pivotal role in experiments that demand precision and accuracy. Whether you’re working in a research lab, a clinical setup, or an industrial environment, choosing the right type of pipette is crucial for achieving reliable results. Let’s explore the various types of pipettes, their unique features, and how they cater to specific applications.

1. Air-Displacement Pipettes

Air-displacement pipettes are among the most commonly used pipettes in laboratories. These pipettes use a piston mechanism to create a vacuum that draws liquid into the disposable tip. Their accuracy makes them ideal for applications such as molecular biology and biochemistry, where small liquid volumes must be measured precisely.

2. Positive Displacement Pipettes

Positive displacement pipettes operate differently, using a piston that directly contacts the liquid. This design eliminates air gaps, making them perfect for handling viscous, volatile, or dense liquids. Researchers working with samples like DNA solutions or hazardous chemicals often prefer positive displacement pipettes for their reliability and minimal contamination risk.

3. Single-Channel Pipettes

Single-channel pipettes are designed for transferring liquid one channel at a time. They’re a staple in labs, particularly for tasks requiring precision, such as preparing serial dilutions or pipetting individual samples. Their ergonomic designs ensure ease of use during repetitive tasks.

4. Multichannel Pipettes

Multichannel pipettes streamline workflows by enabling simultaneous liquid handling across multiple wells. These pipettes are indispensable in high-throughput environments like ELISA assays and plate-based studies, saving time and reducing repetitive strain.

5. Electronic Pipettes

Electronic pipettes bring automation to manual pipetting tasks, improving precision and efficiency. They feature programmable settings and minimal manual effort, making them an excellent choice for repetitive pipetting tasks or when working with delicate samples.

6. Mechanical Pipettes

Mechanical pipettes, also known as manual pipettes, are the traditional choice for scientists. They are robust, cost-effective, and reliable, making them suitable for general lab use. Their straightforward mechanism makes them a go-to option for routine procedures.

7. Micropipettes

Micropipettes are specialized pipettes designed for handling very small liquid volumes, often in the microliter range. They are widely used in genetics, microbiology, and other fields requiring precision at a microscopic scale. Microlit’s range of micropipettes is trusted for its accuracy and ergonomic design.

8. Serological Pipettes

Serological pipettes are often used for transferring larger liquid volumes. These graduated pipettes are a staple in cell culture labs and are typically used with a pipette controller for ease of operation.

9. Pasteur Pipettes

Pasteur pipettes, also called transfer pipettes, are simple and disposable. Made of glass or plastic, they are ideal for qualitative liquid transfers and are commonly used in microbiological and histological applications.

10. Volumetric Pipettes

Volumetric pipettes are designed for delivering a single, precise volume of liquid. Their high accuracy makes them ideal for analytical chemistry applications, such as preparing standard solutions and dilutions.

Choosing the Right Pipette for Your Application

Selecting the appropriate pipette depends on the nature of the experiment, the volume of liquid to be handled, and the required precision. For instance, multichannel pipettes are essential for high-throughput tasks, while micropipettes are indispensable for molecular biology work. Evaluating your lab’s specific needs can guide you toward the best choice.

Maintaining Your Pipettes for Longevity

Proper maintenance is key to ensuring the longevity and accuracy of pipettes. Regular calibration, cleaning, and storage in appropriate conditions prevent wear and tear. Investing in high-quality pipettes, like those from Microlit, ensures durability and consistent performance.

Microlit: Innovating Liquid Handling Solutions

Microlit is a trusted name in liquid handling equipment, offering a diverse range of pipettes tailored to modern laboratory needs. With a focus on ergonomic designs, precision engineering, and customer satisfaction, Microlit’s products stand out in the market. Explore their range to find the perfect pipette for your lab.

Final Thoughts

Understanding the different types of pipettes and their uses ensures that researchers and lab technicians make informed choices, enhancing the accuracy and efficiency of their work. With advancements in pipette technology, tools like Microlit’s range of liquid handling solutions continue to push the boundaries of precision and reliability in laboratories worldwide.

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Different Types of Pipette Tips and When to Use Them

Like deciding what to wear for the day, walking into a laboratory means you have to choose the right pipette tips for your experiments. This is about precision in avoiding mistakes and contamination rather than personal preferences when working in a lab. There are various types of tips, each designed with a specific application in mind.

Below is an ultimate guide on how to make sense of different kinds of pipette tips and their uses.

1. Non-Sterile vs. Sterile Tips

Non-Sterile Tips: These can be used for general laboratory procedures where sterility is not necessary. Using non-sterile tips may save money if you are dealing with non-sensitive samples or performing routine tasks.

Sterile Tips:

Required when doing tests where contamination would lead to compromised results, such as in microbiology, molecular biology or clinical settings. Such tips are pre-sterilized and certified free from contaminants like RNase, DNase, endotoxins etc. Although it might seem appealing to autoclave non-sterile tips onto sterile ones, inconsistent outcomes may occur because autoclaving does not have quality control measures.

2. Filter Tips

Filter Tips They are designed in such a way that prevents aerosols and liquids from entering the pipette body and thus safeguarding your samples as well as the pipette. Whenever you are dealing with volatile substances, corrosives or infectious materials it is important to use them. In some cases like PCR experiments where there is risk of contamination leading to false results, presence of filter tips is compulsory.

3. Long Tips

Long tips can get to the bottom of narrow tubes and deepwell plates without causing contamination towards the pipette’s shaft. In case you are working in a laboratory where you transfer liquids from tall containers, it is advisable to use long tips that maintain sterility and accuracy.

4. Short Tips

If you have short tips, ergonomic pipetting will be made possible, and hence there will be less strain on your arm or hand especially if you are using small well plates or multichannel pipettes. By sitting closer to the bench, they ensure exact pipetting making them the best for such fast robots.

5. Low Retention Tips

Low retention tips refer to those that comprise of special polypropylene blend or else coated with a hydrophobic surface intended for minimizing liquid retention. It is particularly essential when handling viscous or low surface tension liquids like concentrated protein or DNA solutions; this kind of tips ensures maximum sample recovery as well as accurate pipetting which may influence sensitive assays.

6. Wide Bore Tips

In delicate specimens like cell suspensions, standard ones can shear cells mainly due to their small opening; while wide bore tips have bigger holes thus providing easy passage for the solution through them hence preventing damage among other things when dealing with delicate samples such as cells in suspension or very thick liquids.

What Counts Concerning Quality and Fit

Quality of the tips that you get is as important as choosing the right type of tip for your pipette. This is because, by selecting poorly fitting or low quality tips, you risk taking inaccurate measures, adding to the strain of pipetting and contaminating samples in the process. Thus, it is advised that a high-quality tip should be compatible with your pipette for better outcomes and accurate results. Keep in mind therefore, how well the tips fit into your pipette so as to ensure consistency in lab work.

The importance of selecting the correct pipette tip does not depend on someone’s liking but rather impacts on getting reliable results. In order to ensure successful and efficient lab work it is necessary to identify various types of pipette tips and their applications. This blog originally posted here:  Different Types of Pipette Tips and When to Use Them

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Microlit 12 Channel Micropipette

Microlit offers the lightweight variable volume multichannel micropipette for accurate and precise sampling and dispensing of liquid. This 12 channel micropipette has universal tipcone compatible with internationally accepted tips, lightweight & soft grip for maximum user comfort, fully autoclavable. It comes with well designed pippette stand for easily handling of your multichannel pipette. For details, visit https://www.microlit.us/product-category/micropipettes/#post-353

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Next Generation Pipettes Market  Promising Growth Opportunities over 2019-2029

Growing life science industry and laboratories demand highly advance technology and solution to make researcher task easier and reduce errors. Research, development and testing methods are followed by various steps and needs different advance instruments to maximize accuracy and reduce efforts. Life science industry is shifting towards electronically operated liquid handling devices to reduce errors. Researchers are adopting next generation pipettes in the place of glass pipettes, plastic pipettes, mechanical pipette and pipette tips. Switching towards next generation pipettes are included several benefits such as precision, accuracy, efficiency. Next generation pipettes are used routinely in all kind of laboratories from the academic setting to pharmaceutical research labs. Next generation pipettes are available in various shapes and channels with various technologies include in it. Next generation pipettes provide several benefits to the scientist such as save time and reduce strain injury. Next generation pipettes are pre-programmable pipettes with digital display and motor operation which increase accuracy and precision. Next generation pipettes can reduce the possibility of human errors. Availability of multichannel and multifunction operation in the next generation pipettes are provided features such as multi-dispensing, pipetting, reverse pipetting, mixing, and diluting.

Increasing research and development activities and growing investments in biopharmaceutical production boost p the growth of the next generation pipettes market. Growing demand for devices to improve productivity & accuracy, improve lab outcome, and reduce errors drives the next generation pipettes market. Growing DNA based research, cell culture research, increasing drug discovery activities favour the growth of the next generation pipettes market. Growing pharmaceutical and healthcare research spur the demand for ergonomic next generation pipettes among pharmaceutical manufacturers. Moreover, the introduction of robotic-assisted liquid handling systems expected to hamper the demand for electrically operated next generation pipettes over the forecast period.

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The global next generation pipettes market is segmented on basis of product type, and end user and region:

Segmentation by Product Type

Segmentation by End User

Electronic Single Channel Pipettes

Electronic Multi Channel Pipettes

Accessories

Hospitals

Specialty Clinics

Diagnostic Laboratories

Academic Research Institutes

Pharmaceutical & Biotechnology Companies

Next generation pipettes market expected to grow with the major growth rate as growing demand for the electronic and digital device for the liquid handling in the laboratories. Next generation pipettes market is available in the different product type such as electronic single channel pipettes, electronic multi channel pipettes and accessories. Manufactures are focusing on the launch of new products to gain significant market share and provide advanced instruments for laboratory purpose. For instance, recently in February 2019 Andrew Alliance S.A. and Sartorius launched Pipette+ system based on Internet of Things (IoT) solution technology which can transmit data such as step-by-step actions taken by the operator, possible errors, operator identity and more. Next generation pipettes are gaining significant demand in Academic Research Institutes and diagnostic laboratories to maintain workflow and increase diagnostic efficiency.

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North America expected to dominate the next generation pipettes market as advancement in diagnostic laborites and research institutes. Europe expected to contribute the second-highest revenue share in the next generation pipettes market as increasing research and development activities in the European countries such as Germany, the United Kingdom and France. The Asia Pacific next generation pipettes market expected to grow with higher pace as growing need for advanced equipment for diagnostic procedures and growing funding for the research activities. Asian countries such as South Korea, India and China expected to grow with the highest growth rate over the forecast period as the growing adoption of new healthcare technologies and growing government investments for diagnostic laboratories advancement.

Some of the players operating in the global next generation pipettes market are VWR International, LLC., Accuris Instruments, Artel Inc., Hamilton Company, Sartorius AG, Gilson, Inc., Thermo Fisher Scientific, Inc., Eppendorf AG, Greiner Bio-One International GmbH, Integra Biosciences AG and other companies. Manufacturers are focusing on integration with software companies to add new features and advance their next generation pipettes.

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Automated Liquid Handling Market Analysis- KBV Research

Automated Liquid Handling systems have contributed to the rearrangement of research workflows, which has further led to off-putting the manual efforts that are typically involved in liquid transfer operations. Automated liquid handling reflects a set of equipment and instruments that are used for handling liquids and implementing functions relating to liquid transfer within a clinical and research arena.

Intuitive interfaces of automated liquid handling systems enable operators of any skill level to perform their daily tasks effortlessly and with confidence. The systems provide full control of a highly flexible automation. Automated liquid handling systems reduce time spent on repetitive pipetting tasks. They offer systems that are best suitable for medium or high applications along with meeting multiple liquid handling requisites which include channels, liquid volumes, or microplate type. Decreasing sample contamination and improving accuracy in bioassays is possible with these systems.

Manual intervention into research often comes coupled with errors and is not reproducible. It further creates supplementary bottlenecks within the encompassed research experiment when try-outs are not satisfactorily reproduced. These concerns have highlighted the adoption of automated liquid handling systems since their implementation ensures error-free reproducible results.

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Why are ALH systems crucial?

Since multiple variables are affecting the important process in laboratories, choosing the appropriate solution for small volume handling is extremely important. Therefore, numerous labs have turned to automated liquid handling systems to complement improved reliability and increased efficiency to lab processes. One of the key benefits of automated liquid handlers is that they eradicate both person-to-person and day-to-day variability. Further, they generally accomplish this through minimized training that is needed to manually hand out sub-microliter volumes. Automated liquid handles also enable combination with other processing instruments. Through this, automated liquid handlers can be improved to accomplish better results and can be calibrated as per factors like the liquid type.

Types of Automated Liquid Handling Systems

Individual Benchtop Workstation

Individual benchtop workstations are tools that are designed to perform most of the sampling, mixing, and amalgamating liquid samples automatically. Bioresearch laboratories and drug development labs have limited sample contamination and free personnel to perform other tasks by using a multipurpose liquid handling automated workstation. The workstations are capable of measuring samples, add reagents, and ensure that liquids are added to bioassays in a uniform way. In comparison with other liquid handling systems, benchtop workstations are emerging as one of the top selling products across the globe.

ALH in PCR setup

The automation of PCR setup upsurges reproducibility alongside reducing hands-on time. Automated liquid handlers enable rapid and accurate setup of endpoint, real-time, and multiplex PCR experiments. With platform sizes including benchtop and largely integrated workstations, any throughput requirements can be entertained. Automated liquid handlers offer solutions for any PCR automation needs.

 ALH in Serial Dilution

Serial dilutions are a commonly used application in a lab. The user pipettes concentrated sample into the desired location and fill a series of additional locations which contain a fixed amount of diluent. Lab automation is the most appropriate choice for simplifying serial dilutions along with assuring utmost accuracy. A multi-channel automated pipettor has the capability of carrying out serial dilutions of eight to twelve samples simultaneously.

ALH in Plate Reformatting

Owing to the surging liquid handling constraints, sample reformatting turns out to be an expensive process. Plate reformatting is the process in which samples are moved from one container to another. The flow must be carefully performed to avoid unnecessary container format changes. Automated liquid handlers are used for compound management. These offer full plate dilutions and reformatting from source plates to assay plates.

Trends & Developments

Liquid handling robots are being used in automating chemical and biochemical laboratories. The robots dispense a specific quantity of reagent, samples, or other liquids into a designated container. Several liquid handling workstations can conduct multiple lab unit operations like sample mixing, transport, manipulation, and incubation. Liquid handling robots are available in the market with customizations using different add-on modules like PCR machines, colony pickers, etc. Manufacturers are emphasizing on developing automated liquid handling workstations to mix, sample, and combine the liquids.

Automated liquid handling systems extend the range from semi-automated multichannel pipettors to room-sized systems. The industry is evolving toward nifty, modular systems for every budget. Similarly, instrumentation, software, and methods are following the trend toward superior user accessibility.

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