#How's this for size?

[technovillain]

i come from the universe where everything is the same except disney heroines get like an ounce of their fathers' obviously dominant genes and their clothes are like 80% more historically accurate. it's beautiful here.

[2] [3]

[scalierpepper]

I got commissioned to paint griddlehark imagined as a classic romance novel cover, which needless to say is one of the greatest commissions of all time and I had an absolute blast.

Per the commissioner's request, I've also uploaded this art to INPRNT (link here).

Art without typography and a mock-up for fun under the cut!

[albinogel]

[barghest-land]

working on early horses, i wanted to do a quick sketch to show how small Eohippus was compared to an extant horse (this one is about 150cm tall). as you can see, it wasn't big at all. a perfect little lap horse :)

[starleska]

how tall is Tenna?! here's a rough estimate 📺👀

so we haven't had any official confirmation of Tenna's ridiculous height yet, and i haven't been able to yank sprites from the game... however. there's a handy little Deltarune height chart made by an anonymous user some time ago, which gives a rough indication of the height of each character:

crucially, we see Kris' height is 5'1.5": this is great for us, because we see Kris next to Tenna frequently!!

if we round down Kris' height to 5", we see that Tenna is approximately three Krises tall without his antennae, and nearly four Krises with them!!

that means Tenna is at least 15 feet tall, but if you count the antennae, his whole height is closer to 19 feet.

good grief 😳

[artkaninchenbau]

Crocodile finds a strange stray cat an 11-year old Nico Robin (AU where they met 13 years earlier. Robin's been on the run from the World Government for 3 years. Crocodile's 27 and has not set up base in Alabasta yet)

It seems like I have become possessed. By some sort of demon.

Bonus:

[lauraneedstochill]

“The Pitt” characters + tumblr posts that are definitely about them part 2 (original posts: x, x, x, x, x, x, x) (part 1, 3, 4, 5)

[heyhanibee]

cliffhanger so disrespectful i had to draw it sorry🐸🐸🐸

[zeropro]

Now we just need Starscream with some kitties to complete the trio of goobers and their pets :D

pspspspsps

[lintufriikki]

portable boyfriends 🖤💖💙🎶

[kalwithatrenchcoat]

Burrito, Worm, Mother Hen, Snake, Bean, Loaf...what's next?

[seefasterdraws]

“you were a wonderful experience”

“you were… everything”

[turtleblogatlast]

Leo learns something about himself 🏳️‍⚧️

Based roughly on this old post.

Bonus:

[Leo is taking the fact that he was born biologically female simultaneously very well and also not so well but overall he’s mostly coping with the fact that it was Draxum that just essentially gave him the turtle equivalent of ‘The Talk’.]

[geomimetry]

huggies

[reasonsforhope]

A new treatment combining ReCET and semaglutide could eliminate the need for insulin in type 2 diabetes, with 86% of participants in a study no longer requiring insulin therapy. The treatment was safe and well-tolerated, and further trials are planned to confirm these results.

Groundbreaking research presented at UEG Week 2024 introduces a promising new treatment approach for type 2 diabetes (T2D) that has the potential to greatly reduce or even eliminate the need for insulin therapy.

This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of patients.

Globally, T2D affects 422 million people... While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects... and further complicate diabetes management. [Note: Also very importantly it's fucking bankrupting people who need it!!] A need therefore exists for alternative treatment strategies.

Study Design and Outcomes

The first-in-human study included 14 participants aged 28 to 75 years, with body mass indices ranging from 24 to 40 kg/m². Each participant underwent the ReCET procedure under deep sedation, a treatment intended to improve the body’s sensitivity to its own insulin. Following the procedure, participants adhered to a two-week isocaloric liquid diet, after which semaglutide was gradually titrated up to 1mg/week.

Remarkably, at the 6- and 12-month follow-up, 86% of participants (12 out of 14) no longer required insulin therapy, and this success continued through the 24-month follow-up. In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%.

Tolerability and Safety

The maximum dose of semaglutide was well-tolerated by 93% of participants, one individual could not increase to the maximum dose due to nausea. All patients successfully completed the ReCET procedure, and no serious adverse effects were reported.

Dr Celine Busch, lead author of the study, commented, “These findings are very encouraging, suggesting that ReCET is a safe and feasible procedure that, when combined with semaglutide, can effectively eliminate the need for insulin therapy.”

“Unlike drug therapy, which requires daily medication adherence, ReCET is compliance-free [meaning: you don't have to take it every day], addressing the critical issue of ongoing patient adherence in the management of T2D. In addition, the treatment is disease-modifying: it improves the patient’s sensitivity to their own (endogenous) insulin, tackling the root cause of the disease, as opposed to currently available drug therapies, that are at best disease-controlling.”

Looking ahead, the researchers plan to conduct larger randomized controlled trials to further validate these findings. Dr. Busch added, “We are currently conducting the EMINENT-2 trial with the same inclusion and exclusion criteria and administration of semaglutide, but with either a sham procedure or ReCET. This study will also include mechanistic assessments to evaluate the underlying mechanism of ReCET.”

-via SciTechDaily, October 17, 2024

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Note: If it works even half as well as suggested, this could free so many people from the burden of the ongoing ridiculous cost of insulin. Pharma companies that make insulin can go choke (hopefully).

[hearts-forkoo]

He’s so big????