#Raloxifene

[desianarchist]

A little happy with how far i've come (: x One year on HRT! (Including raloxifene so I don't get boobs. Ask away)

[quark-nova]

hey so I don't see many amab enbies on here and I was wondering if you had any experience with SERMs. Most of the discussion around it seems to be transfem targeted from what I've seen and im not one (even though I've tried to id as one). i do want my body to be androgonized more and it does make me very dysphoric thay it isn't, but I also worry about losing facial/body hair and genital atrophy, along with the fact that I don't want breasts. so I've been hesitant to start hrt. i haven't really been able to find anybody out there with my transition goals and even less resources about hrt. would staying off hrt be the best bet for me and my dysphoria, I only really want fat redistribution and head hair fullness but everything else is unappealing (especially facial/body hair thinning and genital atrophy). Would SERMS be viable for that need or am I just screwed.

Thanks a lot! Yep, I'm currently using SERMs (raloxifene, more precisely), and I've been taking them for a few months along with antiandrogens, although the effects have been quite slow. For now, I've seen a little bit of androgynization/fat redistribution, and no percievable hair thinning yet (which is frustrating for me, especially since I'm doing laser at the same time), although I also experienced genital atrophy. So, not sure it's the best bet for you, but depending on how important each of these are it could be - in any case, it's something that acts way slower than regular feminizing HRT

[cant-afford-lobotomy]

Anyone considering taking estrogen but doesn't want breasts should look into Selective Estrogen Receptor Modulators (SERMS) such as Raloxifene. Essentially it does everything that normal estradiol does except it doesn't cause breast growth (ok sometimes it does but it is greatly reduced)

[raloxefene]

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[del-metais]

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[mlembug]

Non-binary transfems on raloxifene finally get their representation

[curtig]

The fun thing about gender and DIY is that you can just go on and off estrogen on a vibes based schedule while throwing a few pushups into the mix just to try get the correct amount of tits.

[mosasadogs]

i think sometimes everyone wishes they were a 6’1” they/them twink on raloxifene

[anomalocariscanadensis]

maybe i should try hrt again. when i stopped they did give me a ref for someone who apparently prescribes raloxifene but i never followed it up

[makorays]

I'm sorry that many of your askers seem to believe that someone being a femboy is a free ticket to act however the fuck they please around them. I'd like to ask some normal questions about the femboy experience and subculture, if you don't mind.

Firstly, what would you consider the best and worst parts about being a femboy?

Are there any "beginner mistakes" or otherwise regretted things you would do differently were you to start your femboyism journey over?

And, finally, would you have any advice for other people looking to become femboys? (genuinely not me, I just find this stuff interesting)

the best part is having the confidence to be cute and silly without coming off as weird, the worst part is having a type of body dysphoria so specific that not even hormone therapy can get me where i want because i have to grow tits as payment for all the actually desirable benefits it gives me.

if i started hormone therapy today i would probably be DIYing it while using raloxifene as a SERM to prevent breast tissue growth. i don't really recommend doing that without a doctor's guidance but if i had known there was a risky yet feasible way to become curvier without growing breasts i'd have done that instead of just standard HRT. so that's my biggest regret, as far as other mistakes uhhhh well if you click on my older videos you can hear i was kinda trying too hard with my voice and it took me a while to figure out how to make it more calm and natural.

my best advice for other femboys: don't compare yourself to anime traps or 110 pound twitter twinks with curvy asses and 8 inch dicks. some people are just built different and you'll likely never look quite like that. just focus on shaping yourself into the prettiest version of yourself you can achieve.

[autogynocrat]

have you used raloxifene before? if so, how did it effect you?

made my bones hurt and boobs shrink a little but not disappear

eventually i stopped bc the constant bone pain was being too much

some time after that i found myself accepting my boobs and wanting them to become bigger instead

[veroclinics]

Empowering Women's Health: Exploring Hormone Therapy Options

Women's health encompasses a broad spectrum of needs, from reproductive health to menopausal management and beyond. Hormone therapy plays a crucial role in addressing various hormonal imbalances and symptoms that women may experience throughout their lives. In this exploration, we delve into the diverse landscape of hormone therapy for women, empowering them to make informed decisions about their health and well-being.

Understanding Hormonal Imbalances in Women

Hormonal imbalances can manifest in various ways throughout a woman's life, affecting physical health, emotional well-being, and overall quality of life. From menstrual irregularities and fertility challenges to menopausal symptoms and hormonal disorders, women may encounter a range of hormonal issues that warrant intervention.

Common hormonal imbalances in women include estrogen dominance, progesterone deficiency, thyroid dysfunction, and adrenal insufficiency. These imbalances can lead to symptoms such as irregular periods, hot flashes, mood swings, fatigue, weight changes, and decreased libido, among others.

Exploring Hormone Therapy Options

Hormone therapy offers a range of options for addressing hormonal imbalances and alleviating associated symptoms in women. Depending on the specific needs and health goals of each individual, various hormone therapy modalities may be considered:

Conventional Hormone Replacement Therapy (HRT): Conventional HRT involves the administration of synthetic hormones, typically estrogen and progesterone, to alleviate symptoms of menopause, such as hot flashes, night sweats, and vaginal dryness. While effective for symptom relief, conventional HRT has been associated with certain risks, including an increased risk of breast cancer, cardiovascular disease, and venous thromboembolism.

Bioidentical Hormone Therapy (BHT): Bioidentical hormone therapy utilizes hormones derived from plant sources and formulated to mimic the molecular structure of hormones produced by the human body. Bioidentical hormones, such as estradiol, progesterone, and testosterone, are believed to offer a more natural and physiological approach to hormone replacement. However, the safety and efficacy of bioidentical hormone therapy remain subjects of debate and ongoing research.

Selective Estrogen Receptor Modulators (SERMs): SERMs are a class of medications that selectively modulate estrogen receptors in the body, exerting estrogenic or antiestrogenic effects depending on the tissue type. Medications such as tamoxifen and raloxifene are commonly used in the management of conditions such as breast cancer, osteoporosis, and menopausal symptoms.

Estrogen Replacement Therapy (ERT): Estrogen replacement therapy involves the administration of estrogen alone, typically for women who have undergone surgical menopause or have had their uterus removed (hysterectomy). ERT can effectively alleviate symptoms of menopause while reducing the risk of endometrial hyperplasia and cancer associated with unopposed estrogen use.

Non-Hormonal Therapies: In addition to hormone therapy, non-hormonal approaches may be considered for managing hormonal imbalances and associated symptoms in women. These may include lifestyle modifications, dietary interventions, herbal supplements, acupuncture, and cognitive-behavioral therapy (CBT), among others.

Considerations for Women's Hormone Therapy

When considering hormone therapy options, women should take into account various factors to ensure safety, efficacy, and personalized care:

Individual Health Profile: Each woman's health profile, including medical history, hormone levels, age, and lifestyle factors, should be carefully evaluated to determine the most appropriate hormone therapy approach.

Symptom Severity and Impact: The severity and impact of symptoms, such as frequency, intensity, and interference with daily activities, should be considered when selecting hormone therapy options and determining treatment goals.

Risk-Benefit Assessment: A thorough risk-benefit assessment should be conducted to weigh the potential benefits of hormone therapy, such as symptom relief and improved quality of life, against the risks of adverse effects, including cancer, cardiovascular disease, and thromboembolic events.

Monitoring and Follow-Up: Regular monitoring and follow-up with healthcare providers are essential to assess treatment response, monitor hormone levels, and adjust therapy as needed to optimize outcomes and minimize risks.

Conclusion: Empowering Women's Health Through Informed Choices

In conclusion, hormone therapy offers a range of options for addressing hormonal imbalances and improving women's health and well-being. By understanding the diverse landscape of hormone therapy modalities, considering individual needs and health goals, and collaborating with knowledgeable healthcare providers, women can make empowered decisions about their hormonal health.

Whether opting for conventional hormone replacement therapy, exploring bioidentical hormone therapy alternatives, or considering non-hormonal approaches, women have the opportunity to tailor their hormone therapy experience to suit their unique needs and preferences. With personalized care, informed decision-making, and comprehensive support, women can embark on a journey towards hormonal balance, vitality, and optimal health.

[chokchai1555]

วัยทอง คืออะไร อาการคุณเข้าข่ายหรือยัง?

วัยทองคืออะไร?

วัยทอง (Menopause) คือ ภาวะที่สตรีเข้าสู่วัยหมดประจำเดือน โดยรังไข่จะหยุดสร้างฮอร์โมนเพศหญิงที่มีชื่อว่า เอสโตรเจนและโปรเจสเตอโรน ส่งผลให้ไม่มีประจำเดือน ถ้าประจำเดือนขาดหายไปครบ 1 ปี แสดงว่ารังไข่ได้หยุดทำงานแล้ว และถือว่าได้เข้าสู่วัยทองอย่างสมบูรณ์ โดยอายุเฉลี่ยที่ผู้หญิงไทยเข้าสู่วัยทองประมาณ 48-52 ปี สังเกตอาการ “วัยทอง”

*อาการร้อนวูบวาบ (hot flush) โดยเฉพาะบริเวณลำตัวส่วนบน เช่น บริเวณหน้า คอ และอก มักเกิดอาการนานประมาณ 1-5 นาที ร่วมกับ อาการอื่น ได้แก่ เหงื่อออก หนาวสั่น วิตกกังวล หรือใจสั่นได้ อาการเหล่านี้อาจรบกวนการใช้ชีวิตประจำวัน และการนอนหลับยากขึ้นได้ *ช่องคลอดแห้ง ติดเชื้อและคันในช่องคลอด เจ็บขณะมีเพศสัมพันธ์ได้ *โรคกระดูกพรุน *โรคไขมันในเลือดสูงเพิ่ม โอกาสเสี่ยงต่อการเกิดโรคหลอดเลือดหัวใจอุดตันมากขึ้น เนื่องจากจากการขาดเอสโตรเจน เพราะฮอร์โมนเอสโตรเจนทำหน้าที่สำคัญในการลดไขมันไม่ดี( LDL) *เพิ่มความเสี่ยงการเป็นโรคอัลไซเมอร์ *ซึมเศร้า อารมณ์หงุดหงิด มีความวิตกกังวลง่าย *ผิวหนังเหี่ยวแห้ง และบาง ขาดความยืดหยุ่น เป็นแผล และกระได้ง่าย

วัยทองรักษาได้หรือไม่?

*การรักษาโดยการให้ฮอร์โมนเพศหญิงทดแทน (hormone replacement therapy: HRT) ใช้เฉพาะผู้ที่มีอาการรุนแรงและไม่มีข้อห้ามใช้ฮอร์โมนเพศหญิงทดแทน *กลุ่มยาที่ไม่ใช่ฮอร์โมนเพศหญิง (non-hormonal treatment) ได้แก่ กลุ่มยารักษาโรคซึมเศร้า (antidepressant) เช่น ยากลุ่ม SSRIs และ SNRIs ยากลุ่ม selective estrogen receptor modulators (SERMS) ตัวอย่างยาได้แก่ tamoxifen, raloxifene เป็นต้น ยา tibolone และ androgen เป็นต้น

วิธีดูแลตนเองรับมือกับวัยทอง

อาหาร สตรีวัยทองควรกินอาหารให้ครบ 5 หมู่ และเน้นการกินอาหารที่มีแคลเซียมสูง เช่น นม โยเกิร์ต พืชตระกูลถั่ว เต้าหู้ งาดำ ปลาตัวเล็ก ผักใบเขียว เป็นต้น แคลเซียมที่รับเข้าไปจะเป็นตัวเสริมสร้างกระดูกเพื่อป้องกันภาวะกระดูกพรุน นอกจากนี้ ควรควบคุมระดับไขมันในเส้นเลือดโดยงดอาหารที่มีคอเลสเตอรอลสูง และเลือกกินอาหารที่ย่อยง่าย

ออกกำลังกายอย่างสม่ำเสมอ เช่น การเดิน การวิ่งเหยาะๆ เต้นรำ รำมวยจีน เต้นแอโรบิก เป็นต้น

ฝึกการควบคุมอารมณ์ให้มีความคิดในทางบวก และทำจิตใจให้แจ่มใสเบิกบาน

ตรวจร่างกายอย่างสม่ำเสมอปีละ 1 ครั้ง ตรวจเช็คความดันโลหิต ตรวจเลือดหาระดับไขมัน ตรวจภายในเช็คมะเร็งปากมดลูก ตรวจหามะเร็งเต้านม (Mammography) ตรวจหาความหนาแน่นของกระดูก (Bone Mineral Density) รวมทั้งการตรวจระดับของฮอร์โมนที่เกี่ยวข้องกับวัยทอง

ปรึกษาแพทย์เพื่อพิจารณารับฮอร์โมนทดแทน ในกรณีที่สตรีวัยทองมีอาการต่างๆ มาก หรือตรวจพบความผิดปกติ เช่น กระดูกบาง หรือกระดูกพรุน และมีความจำเป็นจะต้องได้รับฮอร์โมนเพิ่มเติม แพทย์จะพิจารณาให้ฮอร์โมนทดแทนตามความเหมาะสม

ผลดีของฮอร์โมนทดแทน ช่วยรักษาอาการต่างๆ ของภาวะขาดฮอร์โมนเอสโตรเจน อาการที่สำคัญได้แก่ อาการร้อนวูบวาบและลดการสูญเสียมวลกระดูก จึงช่วยป้องกันภาวะกระดูกบางและกระดูกพรุน นอกจากนี้ ยังรักษาอาการช่องคลอดแห้งที่เกิดจากการขาดฮอร์โมนเอสโตรเจน และช่วยป้องกันโรคมะเร็งลำไส้ใหญ่

ผลเสียของฮอร์โมนทดแทนที่อาจเกิดขึ้น อาการข้างเคียงหรืออาการไม่พึงประสงค์ เช่น เลือดออกทางช่องคลอด คัดตึงเต้านม น้ำหนักเพิ่ม เวียนศีรษะ คลื่นไส้ อาเจียน ขาบวม เพิ่มความเสี่ยงต่อโรคหลอดเลือดดำอุดตัน และอาจเพิ่มความเสี่ยงต่อการเกิดมะเร็งมดลูก มะเร็งเต้านม โดยเฉพาะผู้ที่ใช้ในปริมาณที่สูง และใช้ติดต่อกันนาน 10-15 ปี ซึ่งการใช้ฮอร์โมนทดแทนไม่ควรใช้ติดต่อนานเกิน 5 ปี

ผู้ที่ควรหลีกเลี่ยงการใช้ฮอร์โมน

ผู้ที่มีประวัติมะเร็งเต้านม และมะเร็งมดลูก

ผู้ที่เป็นโรคตับ

ผู้ที่เกิดลิ่มเลือดที่เท้า

ผู้ที่มีประจำเดือนผิดปกติโดยไม่ทราบสาเหตุ

อาจจะมีหลายสิ่งหลายอย่างที่เปลี่ยนแปลงไปเมื่อเข้าสู่วัยทองและถ้าอาการเหล่านั้นส่งผลกระทบต่อการใช้ชีวิตประจำวันควรมาปรึกษาและตรวจสุขภาพวัยทองกับแพทย์ผู้เชี่ยวชาญแต่เนิ่นๆเพื่อก้าวเข้าสู่วัยทองอย่างมีความสุขและมีคุณภาพชีวิตที่ดี… หวยเด็ด

[adorefem]

A Comprehensive Guide to Letrozole – Uses, Side Effects, & Warnings

Letrozole is a medication prescribed for the treatment of early breast cancer in postmenopausal women who have undergone other forms of treatment such as surgery or radiation. In this blog, we will delve into the intricacies of Letrozole, exploring its uses, dosage, precautions, and potential side effects. Understanding this medication is crucial for individuals navigating through breast cancer treatment, and it’s essential to be well-informed to make informed decisions about one’s health.

Why is Letrozole Prescribed?

Letrozole is classified as a nonsteroidal aromatase inhibitor, designed to treat early breast cancer in postmenopausal women. It is particularly recommended for those who have undergone menopause and have already received tamoxifen treatment for five years. Additionally, Letrozole is used as the first treatment for breast cancer that has spread within the breast or to other parts of the body.

The medication operates by reducing estrogen production in the body, thereby hindering the growth of certain types of breast cancer cells that rely on estrogen for their development.

How Should Letrozole be Used?

Letrozole is administered orally, typically once a day, with or without food. Adhering to a consistent schedule is essential, and patients are advised to follow the prescription label instructions meticulously. It may be necessary to continue the medication for several years, and patients are urged not to discontinue Letrozole without consulting their healthcare provider.

Special Precautions and Considerations:

Before starting Letrozole, patients need to be aware of specific precautions and considerations. These include:

Allergies: Individuals should inform their doctor about any allergies to Letrozole or its components.

Medication Interactions: Letrozole may interact with other medications, including those containing estrogen, hormonal contraceptives, raloxifene, and tamoxifen.

Medical Conditions: Patients with high cholesterol, osteoporosis, or liver disease should communicate this information to their healthcare provider.

Pregnancy and Breastfeeding: Letrozole is exclusively for postmenopausal women who cannot become pregnant. Pregnant or breastfeeding individuals should notify their doctor before initiating the medication.

Drowsiness: Letrozole may cause drowsiness, impacting the ability to operate machinery or drive. Patients should exercise caution until they understand how the medication affects them.

Dietary Instructions:

In general, patients are advised to maintain their regular diet unless instructed otherwise by their healthcare provider.

What to Do if a Dose is Missed?

If a dose is missed, patients should take it as soon as they remember. However, if it’s close to the next scheduled dose, a double dose should not be taken.

Potential Side Effects:

Letrozole may induce various side effects, ranging from mild to severe. Common side effects include hot flushes, night sweats, nausea, and constipation. It is essential to notify the doctor if these symptoms persist or worsen.

Serious side effects such as chest pain, rash, difficulty breathing, or unusual bleeding require immediate medical attention. Letrozole may also contribute to or exacerbate osteoporosis, impacting bone density.

Letrozole, a potent medication, stands as a crucial tool in the fight against certain types of breast cancer, particularly hormone-receptor-positive breast cancer in postmenopausal women. Its role extends beyond treatment; it is also employed in preventing the recurrence of cancer. Understanding the mechanism of Letrozole and adhering to the prescribed guidelines are pivotal in maximizing its effectiveness. This article explores the usage, dosage, and essential considerations associated with Letrozole in breast cancer treatment.

Understanding Letrozole’s Mechanism:

Letrozole operates by targeting hormone-receptor-positive breast cancer, a type of cancer stimulated to grow faster by the natural hormone estrogen. This medication plays a vital role in inhibiting the production of estrogen in the body, thereby impeding or reversing the growth of these specific breast cancers. By doing so, Letrozole becomes an integral part of the comprehensive treatment strategy against hormone-driven breast cancers.

How to Use Letrozole:

Patients are advised to familiarize themselves with the Patient Information Leaflet provided by the pharmacist before initiating Letrozole. Any queries or concerns should be discussed with the doctor or pharmacist for clarity.

Letrozole is taken orally, with or without food, as directed by the treating physician. Typically prescribed as a once-daily regimen, the dosage is tailored to each individual’s medical condition and response to treatment. Consistency is key, and patients are urged to take the medication at the same time every day to ensure optimal efficacy.

Dosage Considerations:

The appropriate dosage of Letrozole is determined based on the patient’s medical condition and the response to treatment. It is imperative to adhere strictly to the prescribed dosage to achieve the desired therapeutic outcomes. Deviating from the recommended dosage may compromise the effectiveness of the treatment.

Regular Use for Maximum Benefits:

Letrozole’s efficacy is best realized through regular and consistent use. Patients are encouraged to take the medication at the same time daily to establish a routine. This adherence ensures that the body receives a steady concentration of Letrozole, enhancing its ability to suppress estrogen production and slow down or reverse the growth of hormone-receptor-positive breast cancers. 

      2.Patient Education and Information:

Empowering patients with information about Letrozole is essential. The Patient Information Leaflet serves as a valuable resource, providing insights into the medication, its usage, and potential side effects. Open communication with healthcare providers is encouraged to address any concerns or queries that may arise during the course of treatment.

Conclusion:

Letrozole plays a vital role in the treatment of early breast cancer in postmenopausal women, offering hope and potential for recovery. However, understanding its uses, precautions, and potential side effects is crucial for patients to make informed decisions about their health. Regular communication with healthcare providers and adherence to prescribed guidelines are integral to a successful treatment journey.Letrozole’s role in treating and preventing hormone-receptor-positive breast cancer in postmenopausal women is significant. By inhibiting estrogen production, Letrozole disrupts the growth of specific breast cancers, offering hope and a therapeutic avenue for patients. Understanding how to use Letrozole, following prescribed dosages, and staying informed about the medication contribute to its effectiveness in the comprehensive management of breast cancer. As research progresses, Letrozole continues to be a cornerstone in the fight against hormone-driven breast cancers, emphasizing the importance of patient education and adherence to prescribed guidelines.

Source: https://www.adorefem.com/a-comprehensive-guide-to-letrozole-uses-side-effects-warnings/