#acellular

[johniac]

SciTech Chronicles. . . . . . . . .Feb 7th, 2025

[creativeera]

The Growing Acellular Dermal Matrices Industry is Thriving on Advanced Wound Care Innovations

The acellular dermal matrices market caters to the need for advanced wound care products that facilitate faster healing of complex wounds and burns. These tissue grafts derived from donated human or animal dermal tissue serve as a scaffold that aids skin or soft tissue regeneration. Comprising an intact matrix of collagen and protein fibers that stimulate cell migration and new tissue formation, acellular dermal matrices reduce healing time and scarring for wounds that fail to heal naturally.

The Global Acellular Dermal Matrices Market is estimated to be valued at US$ 10.14 Mn in 2024 and is expected to exhibit a CAGR of 5.9% over the forecast period 2024 to 2031. Key Takeaways Key players operating in the acellular dermal matrices are Merck & Co., Inc. (Merck Animal Health), Ceva, Zoetis Services LLC, Boehringer Ingelheim International GmbH. The growing prevalence of chronic wounds and ulcers due to the high incidence of diabetes and old age related disorders has bolstered demand for advanced wound care products. North America dominates the market currently due to favorable reimbursement policies and growing awareness about advanced wound management. However, the rising geriatric population in Asia Pacific and Latin America is expected to drive the market expansion in these regions during the forecast period. Market key trends The increased adoption of Acellular Dermal Matrices Market Demand for use in plastic and reconstructive surgeries indicate one of the key trends in the industry. By serving as a dermal substitute, these grafts enable surgeons to repair soft tissue deficits and skin defects with reduced contracture, distortion, and scarring for procedures like breast reconstruction and hernia repair. The advantages over autografts like reduced donor site morbidity have augmented their uptake in cosmetic surgical procedures.

Get more insights on Acellular Dermal Matrices Market

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Alice Mutum is a seasoned senior content editor at Coherent Market Insights, leveraging extensive expertise gained from her previous role as a content writer. With seven years in content development, Alice masterfully employs SEO best practices and cutting-edge digital marketing strategies to craft high-ranking, impactful content. As an editor, she meticulously ensures flawless grammar and punctuation, precise data accuracy, and perfect alignment with audience needs in every research report. Alice's dedication to excellence and her strategic approach to content make her an invaluable asset in the world of market insights.

(LinkedIn: www.linkedin.com/in/alice-mutum-3b247b137 )

[shradhacmi]

Global Acellular Dermal Matrices Market Is Estimated To Witness High Growth Owing To Increasing Adoption of Regenerative Medicine

Market Overview: The global Acellular Dermal Matrices Market is estimated to be valued at US$7,014.0 million in 2021 and is expected to exhibit a CAGR of 12.1% over the forecast period 2022-2030, as highlighted in a new report published by Coherent Market Insights. Acellular dermal matrices are biomaterials derived from human or animal tissues that have been processed to remove cells, leaving behind the extracellular matrix. These matrices are used in a variety of clinical applications, including wound healing, reconstructive surgery, and regenerative medicine. They provide structural support and act as a scaffold for cell growth and tissue regeneration. Market Dynamics: 1. Increasing demand for regenerative medicine: Acellular dermal matrices play a crucial role in regenerative medicine by providing a supportive structure for cell growth and tissue regeneration. The growing prevalence of chronic diseases and traumatic injuries has led to an increasing demand for regenerative medicine solutions, thereby driving the market growth. For instance, according to the World Health Organization (WHO), approximately 15 million people suffer from stroke worldwide each year, creating a significant demand for regenerative therapies. 2. Advancements in technology: The development of advanced processing techniques and innovations in tissue engineering have contributed to the growth of the acellular dermal matrices market. New methods for decellularization and sterilization have improved the safety and efficacy of these matrices. Furthermore, the integration of technologies such as 3D printing and biofabrication has enhanced the customization and precision in the production of acellular dermal matrices, catering to specific patient needs. SWOT Analysis: Strengths: 1. Enhanced tissue regeneration: Acellular dermal matrices provide a favorable environment for tissue regeneration, promoting wound healing and improving patient outcomes. 2. Versatile clinical applications: These matrices can be used in various clinical applications, including reconstructive surgery, wound healing, and regenerative medicine. Weaknesses: 1. High manufacturing costs: The production of acellular dermal matrices can be expensive, limiting their accessibility in certain regions and healthcare systems. 2. Risk of immune reactions: While efforts are made to remove all cells from these matrices, there is still a risk of immune reactions, which may affect patient outcomes. Opportunities: 1. Growing geriatric population: The aging population is more prone to chronic diseases and age-related tissue degeneration, creating a significant opportunity for the use of acellular dermal matrices in regenerative therapies. 2. Increasing research and development: Ongoing research and development activities in the field of tissue engineering and regenerative medicine present opportunities for the development of novel Acellular Dermal Matrices Market with enhanced properties and clinical applications. Threats: 1. Stringent regulatory requirements: The manufacturing and distribution of acellular dermal matrices are subject to stringent regulatory requirements, which may pose challenges for market players.

[mariacallous]

With vaccination rates among US kindergarteners steadily declining in recent years and Secretary of Health and Human Services Robert F. Kennedy Jr. vowing to reexamine the childhood vaccination schedule, measles and other previously eliminated infectious diseases could become more common. A new analysis published today by epidemiologists at Stanford University attempts to quantify those impacts.

Using a computer model, the authors found that with current state-level vaccination rates, measles could reestablish itself and become consistently present in the United States in the next two decades. Their model predicted this outcome in 83 percent of simulations. If current vaccination rates stay the same, the model estimated that the US could see more than 850,000 cases, 170,000 hospitalizations, and 2,500 deaths over the next 25 years. The results appear in the Journal of the American Medical Association.

“I don’t see this as speculative. It is a modeling exercise, but it’s based on good numbers,” says Jeffrey Griffiths, professor of public health and community medicine at Tufts University School of Medicine in Boston, who was not involved in the study. “The big point is that measles is very likely to become endemic quickly if we continue in this way.”

The United States declared measles eliminated in 2000 after decades of successful vaccination campaigns. Elimination means there has been no chain of disease transmission inside a country lasting longer than 12 months. The current measles outbreak in Texas, however, could put that status at risk. With more than 600 cases, 64 hospitalizations, and two deaths, it’s the largest outbreak the state has seen since 1992, when 990 cases were linked to a single outbreak. Nationally, the US has seen 800 cases of measles so far in 2025, the most since 2019. Last year, there were 285 cases.

“We’re really at a point where we should be trying to increase vaccination as much as possible,” says Mathew Kiang, assistant professor of epidemiology and population health at Stanford University and one of the authors of the paper.

Childhood vaccination in the US has been on a downward trend. Data collected by the Centers for Disease Control and Prevention from state and local vaccination programs found that from the 2019–2020 school year to the 2022–2023 school year, coverage among kindergartners with state-required vaccinations declined from 95 percent to approximately 93 percent. Those vaccines included MMR (measles, mumps, and rubella), DTaP (diphtheria, tetanus, and acellular pertussis), polio, and chickenpox.

In the current study, Kiang and his colleagues modeled each state separately, taking into account their vaccination rates, which ranged from 88 percent to 96 percent for measles, 78 percent to 91 percent for diphtheria, and 90 percent to 97 percent for the polio vaccine. Other variables included demographics of the population, vaccine efficacy, risk of disease importation, typical duration of the infection, the time between exposure and being able to spread the disease, and the contagiousness of the disease, also known as the basic reproduction number. Measles is highly contagious, with one person on average being able to infect 12 to 18 people. The researchers used 12 as the basic reproduction number in their study.

Under a scenario with a 10 percent decline in measles vaccination, the model estimates 11.1 million cases of measles over the next 25 years, while a 5 percent increase in the vaccination rate would result in just 5,800 cases in that same time period.

In addition to measles, the authors used their model to assess the risk of rubella, polio, and diphtheria. The researchers chose these four diseases for their infectiousness and risk of severe complications. While sporadic cases of these diseases do occur and are usually related to international travel, they are no longer endemic in the US, meaning they no longer regularly occur.

The model predicted that rubella, polio, and diphtheria are unlikely to become endemic under current levels of vaccination. Rubella and polio have a basic reproduction number of four, while diphtheria’s is less than three. In 81 percent of simulations, vaccination rates would need to fall by around 35 percent for rubella to become endemic in the next 25 years. Polio, meanwhile, had a 50 percent chance of becoming endemic if vaccination rates dropped 40 percent. Diphtheria was the least likely disease to become reestablished.

“Any of these diseases, under the right conditions, could come back,” says coauthor Nathan Lo, a Stanford physician and assistant professor of infectious diseases.

To evaluate the validity of the model, the researchers ran a scenario with recent state-level vaccine coverage rates over a five-year period and found that the number of model-predicted cases broadly aligned with the number of observed cases in those years. The authors also found that Texas was at the highest risk for measles.

One limitation of the study was that the model assumed that vaccination rates were the same across all communities within a state. It didn’t take into account large variations in vaccination levels. Pockets of low vaccination rates, like in the Mennonite community at the center of the West Texas outbreak, would likely lead to local outbreaks that are larger than expected given the overall vaccination rate.

The study also didn’t take into account the possibility that vaccination rates could rebound in an area in response to an outbreak. “That’s the thing that we have control over. If you’re able to change that cycle, then that disease won’t spread anymore,” says Mujeeb Basit, associate chief of the Clinical Informatics Center at UT Southwestern Medical Center, who wasn’t involved in the study.

Kiang and Lo say the full impact of decreased vaccination will likely not be seen for decades. “It’s important to note that it’s totally feasible that vaccinations go down and nothing happens for a little while. That’s actually what the model says,” Kiang says. “But eventually, these things are going to catch up to us.”

[coffee-mage-sans-caffeine]

Antivaxxers are not responsible* for the current pertussis outbreak. In fact, rich countries are! Here's how:

Whooping Cough, also called pertussis is back in a big way in the US right now. Other nations are also seeing outbreaks, particularly 'rich' or 'first world' or 'developed' nations. Wait what? Rich countries are having a bigger increase in whooping cough than countries with limited healthcare infrastructure? You're probably thinking 'ah, it's the antivaxxers, isn't it?' While they're contributing to the problem, but no, they're not in fact THE PROBLEM. In fact, even fully vaccinated people in rich countries are at risk for pertussis. The first thing to understand is that there are two 'generations' of pertussis vaccine available at present. Both are given in combination with tetanus and diphtheria vaccines. As far as I know, tetanus, diphtheria and pertussis are given together in every mainstream formulation of pertussis vaccine globally. The OG (first gen) pertussis vaccine was the DTP vaccine which contains a whole cell inactivated pertussis bacteria so when it is given, the body develops a robust immune response to every antigen (the thing your body can learn to make antibodies to recognise) on the surface of the pertussis bacteria. It is still used in countries where money is tight because it's cheaper to make and the immune response is robust and long-lasting--5-10 years depending on your source. Unfortunately, side effects were higher with the OG. Some children spike high fevers causing febrile seizures (which are terrifying even though they're benign), arm pain is more intense, and people feel worse after getting it. A miniscule number of children given the OG suffer encephalitis and more serious neurological effects, though most cases self-resolve. In rich countries, as the incidence of pertussis (and diphtheria and tetanus) fell with robust vaccination programs, people became more and more afraid of the side effects of the DTP vaccine. Those side effects sound scarier when there's lower risk of pertussis. There were also ever-growing antivaccine movements because since there has been inoculation (a precursor medical practice to vaccination that goes back all the way to ancient China) there have been opponents inoculation and vaccination. Antivaxxers are not new and modern. They have always been there and they were PISSED about the encephalitis. So both antivaxxers and provaxxers who were starting to forget how scary it is to watch a baby with pertussis said 'we need a better option'. This brings us to 2nd gen vaccines, the acellular pertussis vaccines DTaP and Tdap. The little a stands for 'acellular', meaning that there is no longer a whole dead bacteria cell as our antigen. We use specific cut-up antigens instead. Most formulations use 3-5 different antigens. This results in much lower side effects! Immunity without side effects is the goal! The problem is that this vaccine doesn't last as long. In fact, for 0-10 year old children, 98% are immune at 1 year after vaccination while 81% are immune at 5 years after vaccination. For 11-20 year olds, those numbers drop to 72% at one year and 42% at 5 years after vaccination. For people who are older, those numbers drop even faster. And the acellular vaccines aren't as good at preventing infection--they're more like the covid vaccines in that rather than stopping infection, they make the symptoms less bad. And those 3-5 antigens in the acellular vaccine are becoming less common on the surface of the bordatella pertussis bacteria. Yup. It's out-evolving the vaccine. So where does this leave us? 1) Make sure your pertussis vaccine is up to date. This protects you against the effects of a very serious illness. 2) If you have been exposed to pertussis TALK TO YOUR DOCTOR ABOUT PROPHYLACTIC ANTIBIOTICS. After an hour in a room with someone who has pertussis, if your body doesn't have sufficient immunity there's up to a 90% chance of you getting it and you will be sick for months. This is one of the ONLY CASES EVER where you should be getting prophylactic antibiotics. Usually, I would say do not get prophylactic antibiotics. This is a special case.

3) If a third gen vaccine comes out (many are in development), update your pertussis shot! 4) IF YOU FEEL SICK AND HAVE A COUGH, STAY HOME. If you cannot stay home, then you should wear a well-fitted disposable n95, kn95, or surgical mask (in order of preference) at all times around other people. 5) Mask in crowded public spaces and on airplanes even if you feel well.

[gayofficial]

Vaccine Resources in America

Hi! I just wanted to make a list of programs that provide recommended vaccines at low or no cost in light of everything happening with the department of health and government funding in general. I don't want to scare people, but I cannot imagine that funding for these programs will increase with Trump, Elon, and RFK JR in charge, and there have already been several measles outbreaks in 5 states so far this year, and it is only February.

If you are 18 or younger, the Vaccines for Children program provides free vaccines to those who are American Indian, Alaska Native, Medicaid-eligible, uninsured, and underinsured. Proof of this status is NOT required, and so if you have parents who would not assist in providing documentation, do not worry. Certain providers may ask for an administrative fee, but this will vary by location and will almost certainly be on a sliding scale. These programs are run through your state or territory health departments, which you can find easily through an online search or here.

Many states also offer VFA or Vaccines for Adults programs. Not all of them are called "VFA", but many are. Depending on where you live, searching your state, county, and/or city health department websites can lead you to low and no-cost vaccine programs in your community.

Even if you were vaccinated as a child, if you are unsure if you have received the full recommended vaccine schedule you should still look into these resources. The DTaP (Diptheria, tetanus, and acellular pertussis) vaccine needs a booster every 10 years and/or every pregnancy to retain full effectiveness. You should also get flu and COVID boosters as recommended.

If you decide to call your health department to inquire about specific vaccination resources in your community, you do not need to worry. These people have gone into public health because they want to serve their community and ensure better health outcomes for everyone in it, and that includes you. With all of the vaccine hesitancy brought on by COVID-19, conspiracies about the ingredients inside them, fears that they cause disease, and concerns that they cause autism, your questions and desire to get vaccinated will be welcomed.

If you have any questions feel free to reach out to me and I am more than happy to help you find and reach out to resources specific to your area!

[kyothena]

I’ve figured it out guys Will is actually a blob (Physarum polycephalum)

Alright so you might be wondering what Will has in common with this acellular slime mold, and the answer is.. a lot of things, suprinsigly.

1) they can both clone themselves

2) they can both find their way though a maze

3) They can both appear gluey

4) They can both “come back to life”

5) Blobs can wrap their “veins” around food, Will can wrap his ribbons around people (entanglement)

6) Monty subconsciously comparing Will to a dog, not understanding wtf Will actually is and perhaps growing to like him is very typical behavior for someone who meets a blob/slime mold

Now could someone check if Will can find the shortest way to a source of food 😔🤚

(Idk where this post came from, I was thinking about clones, then about Will, then about how in school a few years ago they made us cut blobs into pieces and the pieces became creatures themselves)

[sweetfirebird]

Things You Can Do Right Now

aside from protesting and harassing Democrats to do things

Get vaccinated (if you can)

MMR (measles, mumps, rubella) vaccines should be good if you received two doses as a child, which most in the US still do. However, enough people haven't now that there is a measles outbreak. Measles wrecks your immune system and also it sucks. So check your records and talk to a doctor. Many cannot get vaccinated because of compromised immune systems, so do it for them. (And because RFKjr sucks rotten eggs)

flu shots! covered by many state and county public health programs! the flu season is already insane, and that's just "regular" flu

Tdap (Tetanus, diptheria, acellular pertussis) -this is the tetanus shot you are supposed to get every ten years. Tetanus is horrible but the concern with this one right now is pertussis (whooping cough). You don't want it and you don't want to spread it to children. It's not their fault their parents won't vaccinate them.

Covid. Obviously. In America, this isn't always covered now, unfortunately, but if it is for you or you can afford it, get it while you can, before that idiot possibly eliminates it.

Protecting public health is community building AND it's protesting these jackasses.

Wear a mask - you don't want to wear it all the time, there is a lot of social pressure, I get it. Then wear one when in hospitals, and on planes/trains etc. (I know some states are trying to make this illegal, because the people obsessed with 'freedom' don't give a shit about yours.)

Wash your hands. This seems obvious to us grownups, but a lot of MAGA types now seem to be deliberately not doing this. And, aside from how it's disgusting, uh, hand sanitizer does not kill Norovirus. Hot water! Soap!

Give to food banks if you can, or contribute to Little Free Pantries or local outreach programs. Fed is best and armies march on their stomachs.

Wash your produce thoroughly before you eat it. Cook your meat thoroughly. Follow the AMA youtube channel for updates on bird flu or other outbreaks that the CDC is no longer/can no longer report on. Orange Asshole is deregulating everything, so... here we are. In hell. Protect your health because he sure as shit isn't.

talk to your neighbors, if you have any and they don't have MAGA shit in their yard. I actually do not have any neighbors that aren't businesses, but I do patronize their businesses (except the real estate office. What am I? Rich? Like I can buy a house. lol)

Check your community boards (NextDoor is weird but it is technically a community board) for local events/needs to see if you can contribute. Does your local senior center or school need donated craft supplies? Is there a pet adoption day looking for volunteers? Is a community outreach group doing free or low cost vaccinations open to the public? Sometimes areas will have free pet spaying/neutering drives for anyone with low income! That might not seem like protesting to you, but using local and government programs is your right and is good, and also you paid for that with your taxes. Use them. Programs that don't get used get cut. (Some are about to get cut anyway grrrr so use them while they exist)

Go to the library. Get a library card. Check out physical books or movies. Use online apps like Libby and Libro.fm *through your library* for free! You are supporting an institution that supports your community. Every year, when it's budget time, the library numbers need to look GOOD, and yes, that is also your tax dollars. So use your libraries!

Be vocal. If you are boycotting Target or Walmart or McDonalds or Airbnb or Starbucks--tell them why. This is email, don't worry, no phone calls required. If you are now shopping at Lush or Costco or Albertson's instead--tell them so as well! Mention it to other people.

yeah it's dumb that in America one of only real ways to be heard is through consumerism but these are all just tools at your disposal. What services are being used, what aren't. Where the dollars go, where they don't.

Start looking up which Republicans--and Democrats--are up for special elections in your area or who need to be Primaried the hell out of the race. If you feel up to it, go volunteer to help, or follow them on social media and start getting aggressive with your support.

If a Democrat *has* done something awesome. (Or you have one of the rare R's who is standing up to this bullshit) then talk about it. (and yes also tell them you thought it was awesome) Democrats are... honestly... they need to learn how to hype themselves up. They don't know how to do this for some reason, so I guess we have to do it for them. They are, like everything else here, a tool that we need to use, for the moment.

Quit fast fashion. It's basically slave labor. It will also save you money and you won't be contributing to this economy. It's also INCREDIBLY better for the environment than polyester crap in landfills--and this administration is not about saving the environment at all. So it's again up to us for now to do what we can. Learn to buy quality pieces, rewear and repair. Thrift well. You can even learn to tailor your own clothes, which looks a thousand times better anyway. (or get them tailored. plenty of small businesses like dry cleaners offer small alternation services, like hemming.)

and finally, for now

get a hobby. I'm not kidding. preferably something tangible, that you can hold in your little hands and see as a final, finished piece. Though if not, reading more or video games and the like are always fine. You are going to want and need distraction, yes, but also *creating* when things are low is so, so good for your brain. And an act of creation while they are trying to destroy everything? is a little 'fuck you' to all of them.

[darkmaga-returns]

In Japan, childhood vaccinations are recommended, not mandatory, after the Immunization Act was amended in 1994 to scrap mandatory inoculation.

Here's a more detailed explanation:

1994 Amendment:The Japanese Immunization Act was revised in 1994, shifting from mandatory to recommended vaccinations.

Recommended Vaccinations:The Japan Pediatric Society still recommends vaccinations for children under two years old, as shown in its recommended vaccination schedule.

Individualized Approach:The revised act also promotes "individual vaccination" based on a physician's assessment of each child's health.

Examples of Recommended Vaccines:Routine recommended vaccines include BCG, acellular pertussis vaccine (DTaP), measles and rubella combined vaccine (MR), inactivated polio (IPV), Hib, PCV7, HPV, and Japanese encephalitis vaccine (JEV).

Voluntary Vaccines:Hepatitis B (HBV), mumps, varicella, and rotavirus vaccines are considered voluntary.

Vaccination Vouchers:In cities like Hiroshima, vaccination vouchers issued by the city are required to get vaccinations, and these vouchers can only be used by residents of the city at the time of inoculation.

Perhaps the United States and other countries should take a careful look at Japan in terms of health, longevity, and diseases linked to excessive vaccination such as atopic conditions, neuropsychiatric syndromes, and autoimmunity.

[us-cj]

PennState Center for Infectious Disease Dynamics study found that whooping cough "...vaccination led to a 40-fold enhancement of B. parapertussis colonization in the lungs of mice.... Despite this vaccine being hugely effective against B. pertussis, which was once the primary childhood killer, these data suggest that the vaccine may be contributing to the observed rise in whooping cough incidence over the last decade by promoting B. parapertussis infection. "

http://epidemics.psu.edu/articles/view/acellular-pertussis-vaccination-enhances-b.-parapertussis-colonization

[puckpocketed]

OFUHFHFJG???? LOBSAVE… mackblack u getting an extra helping of DTaP vax (diptheria tetanus acellular pertussis) COME HERE

[curiouscorvidcreaturecompendium1]

P. Megapituita, an acellular slime mold protist or myxomycete (popularly known by adventurers and dungeon crawlers as the "Gelatinous Slime" or "Slime Cube"), is a protist with diverse cellular forms and broad geographic distribution. The “acellular" moniker derives from the plasmodial stage of the life cycle: the plasmodium is a macroscopic multi-nucleate coenocytic shaped in a network of interlaced tubes. This stage of the life cycle, along with its preference for damp shady habitats, likely contributed to the original mischaracterization of the organism as a fungus.

The plasmodium is typically diploid and propagates via growth and nuclear division without cytokinesis, resulting in the macroscopic multinucleate syncytium; in other words, a gigantic single cell with multiple nuclei. While nutrients are available, the plasmodium can grow to several feet in diameter. Like amoebae, it can consume entire animals by engulfing them.

[creativeera]

Acellular Dermal Matrices: An Overview of Skin Grafting Materials

Acellular dermal matrices, also known as acellular cadaveric dermal allografts, are tissue grafting materials derived from human donated skin that have had the cellular components removed. The remaining dermal collagen and protein matrix provides a scaffold for tissue regeneration and wound healing. Acellular dermal matrices are commonly used in plastic and reconstructive surgeries as alternatives to autografts. Processing and Types of Acellular Dermal Matrices To create an acellular dermal matrix, donated skin undergoes an extensive processing and sterilization protocol to remove donor cells while preserving the collagen structure and biochemical components. This is typically done through repeated cycles of freezing, thawing, and rinsing in detergents. Acellular Dermal Matrices processing leaves behind an acellular, non-immunogenic dermal scaffold. There are a few main types of acellular cadaveric dermal allografts used in surgery based on their intended applications and processing methods: - Thicker sheets for tissue repair and reconstruction, like AlloDerm and FlexHD. These have a dermal thickness of 1-2mm. - Thinner, malleable sheets for contouring soft tissue defects, like AlloMax. These have a dermal thickness of 0.6mm or less. - Custom-shaped grafts that are specially processed and carved to fit specific anatomical sites. Clinical Applications of Acellular Dermal Matrices Breast Reconstruction: acellular cadaveric dermal allografts are commonly used in two-stage tissue expander/implant-based breast reconstruction to help fill dead space, create an integrated pocket, and improve cosmetic outcomes. They reduce capsular contracture rates. Abdominal Wall Reconstruction: Used to repair complex hernias and defects of the abdominal wall by reinforcing weak tissues and preventing recurrence. Provides strength and durability. Facial Reconstruction: Used for contouring facial contour deformities caused by trauma, infection, or cancer resection. Provides a malleable scaffold for soft tissue regeneration. Other applications include repairs of burn wounds, scar revisions, and other soft tissue defects. The acellular collagen matrix promotes revascularization and soft tissue ingrowth. Get more insights on Acellular Dermal Matrices

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Money Singh is a seasoned content writer with over four years of experience in the market research sector. Her expertise spans various industries, including food and beverages, biotechnology, chemical and materials, defense and aerospace, consumer goods, etc. (https://www.linkedin.com/in/money-singh-590844163)

[palmiz]

Raccontino.

A seguito di tosse insistente ad origine faringolaringea, ovvero " di gola", durata alcune settimane giunge in radiologia un giovane cardiologo che lavora nel mio ospedale per eseguire RX torace che risulta negativa per infiltrati polmonari.

Gli dico che potrebbe trattarsi di pertosse da confermare, se vuole, con titolo anticorpale.

Lui sbianca in viso.

E mi racconta che prima della insorgenza della tosse aveva fatto proprio vaccino antipertosse raccomandato a lui e alla moglie incinta di 7 mesi.

Pare ovvio che questa possa essere intesa come reazione avversa al vaccino sotto forma di malattia indotta dal vaccino acellulare, che, come sappiamo, ha indotto resistenza del ceppo originario ormai sostituito dai ceppi pertactina negativi.

Il cardiologo risbianca in viso e mi chiede come faccio a sapere queste cose.

Gli rispondo che leggo articoli del professore Paolo Bellavite e del professore Davide Suraci, ex docente presso nostro ateneo nonché coautore del libro " Operazione Corona, colpo di stato globale".

E trascuro di perdere tempo con le comunicazioni del Quotidiano Sanità.

Bene

Il cardiologo mi informa inoltre di un altro fatto importante che mi riguarda.

Vi ricordate la ragazza che io segnalai sul mio referto ecografico come possibile reazione avversa a 4 dosi di vaccinazione anticovid e ad una dose di vaccinazione antipertosse che lei aveva fatto in gravidanza?

Ebbene Lei, con sospetta sindrome proliferativa post vaccinale sviluppò anche una pericardite per cui fu ricoverata proprio nel reparto di cardiologia del medico in questione.

Pare che il suo caso sia stato oggetto di segnalazione all' AIFA come sospetta reazione avversa dal primario della cardiologia in persona.

Bene.

Ma io non sono mai contenta, e la conversazione continua.

In particolare emergono fatti interessanti che riguardano anche i farmaci di pertinenza prettamente cardiologica: sapevate che i farmaci usati per contrastare la pressione alta chimato beta bloccanti di prima generazione, passando la barriera ematoencefalica causavano turbe del comportamento, alterazioni psichiatriche, incubi notturni, insonnia prolungata e incremento dei tentativi di suicidio?

Ora lo sapete.

Per questo sono stati rimossi dal mercato.

E sostituiti con altri che non causano il suicidio.

Per esempio gli antipertensivi chiamati Ace inibitori.

Come andiamo con gli Ace inibitori?

Con gli Ace inibitori non si è riscontrato un incremento dei tentativi di suicidio tuttavia è stato notato un effetto cancerogeno che si manifesta con netto incremento dei casi di tumore polmonare soprattutto se usati continuativamente per più di 4 anni.

Bene.

Come il Ramipril, rimosso dal mercato perché dichiarato cancerogeno dopo anni di uso, per essere attualmente riimesso sul mercato sotto altro nome ovvero Triatec.

Ripeto: uso prolungato degli Ace inibitori è associato alla insorgenza di tumore polmonare.

E allora come possiamo curare la pressione alta?

Non c' è problema, le linee guida parlano chiaro:

Evitare quando possibile la prescrizione degli Ace inibitori ai pazienti giovani, in quanto, in questi soggetti, avendo una aspettativa di vita più lunga, potrebbe essere incresciosa la insorgenza di una neoplasia polmonare.

Dal fantastico mondo di Cisanello, per oggi è tutto, auguro splendida serata senza incubi, buone cose e buone letture a tutti voi.

Erica Rocchi

[noodle8]

guys if you could have a really big cat-sized type of microorganism and you could do whatever you wanted with it (like have it as a buddy, farm it, whatever), which would you pick? I'll add a few examples of each! :)

Please tell me about your reasoning if u want!!!!

[sun-spice]

Phandom, I need some headcanons on this. I would love to try and write a small textbook style thing on ghost biology, and I'm thinking, is it possible to make organisms that are acellular? What would that look like? Or should I stick with cells? What is the Realms equivalent of DNA and RNA, if there is one? Protein synthesis??? Aaaaaa

For now though:

Yay or nay? Any related headcanons or explanations?