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willowedwisteria · 3 years ago

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Summary -> You got a little... frightened at the cat version of the archons as you returned to the Cafe.

Note -> Since I don't want my works to get mixed up, I'll tag most of my works now as cult! au instead of SAGAU.

Featuring -> Venti, Zhongli, Ei, The Tsaritsa

Genre -> Fluff

The orange and yellow shades of light seep into the empty cafe, leaving the crickets and sounds of emptiness to be filled with meowing and soft purrs.

The wafting smell of coffee and tea fills the area despite the lack of human presence around with the four cats around to hang around in that familiar smell.

In disturbance of the lifeless atmosphere of the cafe, a bell suddenly chimes as you swing the door open.

"I'm back guys!"

And almost immediately, the sound of your voice gets returned by the soft stomping of cats sprinting to you, mewling at you.

Instead of the sight of your most lovely, adorable cats, you see a part of the cats' fur glowing along with their eyes. In the pure darkness that surrounded you, you were creeped out.

One cat, that had the part of fur at the sides of his face flowing, leaped into your warm embrace. Once you got a closer look, you could actually recognize the cat.

"Venti?!"

Then, all of the other cats approached you and began to cuddle your legs. The brown cat, Zhongli, had beaming golden eyes - including a soft gaze.

(Tsaritsa's name) had cold, icy eyes in the shade of a light blue. Yet, her gaze still felt warm around you in contrast.

Sharp eyes, purple glimmering pupils, paired with a look that melted your heart, it kind of fit Ei. Along with a streak of glowing purple fur decorating her back.

You turned on the lights for the Cafe and the glow in their fur and eyes dimmed down. It was... admittedly a pretty sight to see, but your heart almost jumped out of your throat the moment you saw them in the dark.

Letting Venti down from your arms, you melted in your couch and took a deep breath. The Cafe doesn't open on Sundays and you decided to go meet up with your friends, leaving the cats home all to themselves.

To get such a fright was honestly worth it, it'd be better to learn about this earlier rather than when you woke up in the middle of the night.

Oh? The other cats? You decided to let the cats go to a nearby daycare and just relax. Honestly, they seemed more dreadful and disappointed about it.

They were constantly hissing and some almost pulled scratches at the four cats you decided to keep with you for the time being. It was a hefty price to ask the owners to keep so many cats at once.

You thought it would be such a good rest for them, they have to entertain customers constantly every day except for Sundays. Plus, it was a bit stuffy and squeezy to stick in the same tight Cafe.

You assumed, wouldn't some more space and toys be good for them? But it seems like the four cats with you were relishing their lives with you.

Venti jumps onto your lap before the Tsaritsa shoves him aside for a bit more space. Zhongli takes his place next to you and receives your head pats whilst Baal jumps onto the back pillows of the couch to cuddle with your neck and cheek.

Softly, you ponder to yourself about your army of cats, wondering if any others also could glow in the dark.

"Wait... is this even normal for a cat?"

Tag list -> Tag list -> @under-a-starry-night, @yourfaveisblack, @bardisipatos, @callmemeelah, @kithewanderingme, @white-like-dis, @bamboowrites/@bamboowritess, @uchihaeirin, @karmawonders, @lunavixia, @anfre109

Special tags -> @is-very-sad, @chocoenvy, @lovelyy-moraxx,@simplygaile, @azempyrea, @saigomo, @gunterdon, @emilemovhi, @demon-bane, @i-put-the-yan-in-polyandry, @bardisipatos, @xiaophilia, @mari-san-cant, @yuzuricebun, @ventivity, @sweetstrawberrybabe, @euthym1as, @lotterymology, @lina-andel, @matsutake-san, @mx-kamisato, @my-white-canvas

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fatehbaz · 3 years ago

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West African plant knowledge and the origins of a unique species of African rice crop grown in the Americas; fugitive slaves and maroon communities maintaining knowledge of rice in liberated provision gardens; asserting the power and agency of West African knowledge against colonial erasure and obscurity; much more evidence supporting the “Black Rice thesis” has been discovered in the past 20 years; West African plant cultivation traditions in Suriname, Brazil, Colombia, Cuba, and South Carolina demonstrate strength of rice knowledge.

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In 2010 the American Historical Review published a special forum entitled “The Question of ‘Black Rice’”. The collection emerged from an animated debate among historians following the publication of Carney’s book nine years prior (Carney 2001). Black Rice argues that Africans had been growing a species of rice they domesticated independently [...] prior to the start of the transatlantic slave trade. With their knowledge and skills, and despite the constraints of enslavement, Africans introduced this culture into the plantations and societies of the New World. The more conventional belief that Europeans introduced rice into West Africa and then brought knowledge of its cultivation to the Americas, the book argues, is a primary fallacy [...]. At issue was a methodological question, namely what sources and approaches can count as evidence for reconstructing the cultural antecedents of New World developments. [...]

Black Rice broadened the sources of knowledge available to scholars [...]. By examining the transatlantic cultures and landscapes of rice, including its cultivation, milling, and cooking methods, the book analysed the Atlantic history of an important food crop from the perspective of those who grew it, both in Africa and its diaspora. This comparative approach thus draws attention to West Africa -- a region too often ignored in studies of the historical process shaping the environmental transformation of the Americas -- where a distinct species of rice, Oryza glaberrima, had been independently domesticated 3,500 years ago. Focusing on transatlantic flows of knowledge and cultural exchange, the book reconstructed the processes by which enslaved West Africans drove the development of rice landscapes and economies in the Americas using the ancestral skills and knowledge of their homelands. [...]

Despite opposition from some corners, studies of the African contributions to New World risiculture have advanced markedly in the years since the publication of Black Rice, building on its theories and methods and lending support to many of the book’s original findings.

In 2006, Dutch ethnobotanist Tinde van Andel discovered African rice, O. glaberrima, being cultivated in a maroon community in Suriname for use as ancestral offerings in the traditional Afro-Surinamese Winti religion. Applying historical linguistics and later rice genomics, her research built on the theories of African agency presented in Black Rice to explore how Suriname’s maroons have maintained ancestral connections by cultivating African varieties of rice introduced centuries earlier via the transatlantic slave trade [...]. The data suggest that the variety of African rice collected in Suriname likely originated in West Africa’s Guinea Plateau (van Andel et al. 2016a). Published in Nature Plants, the study became the first to use plant genomics to confirm the introduction of crops into the Americas by enslaved Africans [...].

It also shows how African rice endures in Neotropical America as a commemorative heritage plant, symbolising unbroken ancestral connections within a human history that could not be severed by centuries of slavery and racism.

Inspired by her findings with African rice, van Andel went on to examine the African origins of other basic foods produced by Suriname’s maroon communities -- from okra to yams, and from bananas to Bambara groundnuts -- which remain central to the diaspora’s cultural heritage (van Andel et al. 2014, 2016b).

The [...] research conducted by van Andel and her colleagues demonstrates that African rice was indeed introduced to the Americas and associates its cultivation with communities founded by fugitive slaves. Evidence from across the Atlantic World further suggests that similar processes of transatlantic diffusion replicated throughout the Western Hemisphere. In 2011, Carney located a botanical voucher of glaberrima rice in the Natural History Museum in London, originally collected in Matanzas, Cuba, in 1849 [...]. This specimen affirms that African rice was also cultivated in Cuba [...].Consequently, Carney’s original map in Black Rice showing the diffusion of African rice to New World slave societies can now be revised. [...]

Recent work on the material culture surrounding the cultivation of rice in the Americas continues to bolster the Black Rice thesis. Historian Caroline Grego (2021) describes a mud-lifting shovel innovated from the kayendo -- a specialised farm implement developed in West African mangrove rice fields -- that was still in use on plantations in lowland South Carolina in the early 20th century. She blends analyses of historical photographs with field visits, oral histories, archives, and other sources to demonstrate a West African provenance for the shovels [...]. Grego’s research thus fills in more pieces to the complex puzzle of West African influences on the development of rice landscapes and economies in the Americas.

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Working beyond the colonial period, Eloisa Berman-Arévalo builds on Black Rice to analyse how communities in the Colombian Caribbean circumvented agrarian modernisation in the late 20th century through a collective rice harvest known as tongueo. Led by women, the tongueo “re-appropriates and re-signifies” the modern rice harvest as a joyous space of inter-generational Afrodiasporic cultural memory and knowledge transfer [...]. Two decades after publication, the theories and methods of Black Rice continue to influence histories and geographies of (post)colonialism and the African diaspora by clarifying the processes of exchange and innovation that coalesced in the early Atlantic World. [...]

In the many extant maroon communities scattered across northeastern South America, rice remains an esteemed food. Despite the vast distances that separate these communities, from Suriname to Brazil, descendants have passed down similar narratives about how they came to grow rice. Interviews with members of maroon communities (quilombolas) in the Brazilian states of Amapá, Pará, and Maranhão echo what the French botanist André Vaillant observed in French Guiana in 1936 (Carney 2004; Vaillant 1948). While collecting rice from maroon communities near the border with Suriname, Vaillant recorded the widespread belief that Black women introduced rice culture from Africa by hiding the grains in their hair. [...] These oral histories situate the origins of maroon rice culture around slave ships, excess provisions, and the agency of an enslaved African woman [...].

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Images, captions, and text published by: Case Watkins and Judith A. Carney. “Amplifying the Archive: Methodological Plurality and Geographies of the Black Atlantic.” Antipode. April 2022. [Italicized first paragraph/heading added by me.]

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worldburnrp · 4 years ago

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“It was a maddening image —

Little by little, the rooftop space filled up with guests. It’s impossible for a rum-sponsored party not to turn lively; and certainly, it has. While some are happy with their drinks and stay in the venue, drinking and dancing their spirits away — others choose to venture out, either returning to their rooms or getting lost in the maze that are the corridors of The Mark hotel.

In either case, the night is light and young, and there’s not a worry in their minds.

Little do they know however, that in the shadows, the Syndicate awaits.

— and the only way to whip it was to hang on until dusk —

Although the night had been planned to exhaustion, it’d been all but a coincidence that the operation had fallen on the same date as the party launch. It’s a blessing, at the same time that it’s a curse; more people circulating the area isn’t ideal — but a sea of potential issues isn’t so much so, if they’re impaired to begin with.

130 million dollars, gone up in flames. But they ought to make their money back, somehow.

So here the Syndicate hides, and at around 10:30, they strike. Swift and professional as ever, they go completely unnoticed — and they will take all that they can.

A highly effective heist, right under their noses. Those 130 million earned back in just a night.

No wild cards, no action that isn’t necessary, were the instructions given. Money, jewelry, art, anything of true value — that’s what they’re after. Designed as a victimless crime as far as bloodshed goes, the Syndicate still accounts for all. No issue, lest you get in their way.

— and banish the ghosts with rum.”

Unfortunately however, some unlucky few have. As instructed, should anyone be a concern, be it that they’re found in their rooms or other areas in the midst of the operation — they should be neutralized, by whatever means necessary. All with still keeping their anonymity, and succeeding at their tasks.

The pairs that have crossed paths are:

Ludovica Malatesta and Rus Ralston

Nora Vidal and Lee Malkovich

Zafar and Mathias Cain

Vir Zafar and Ibrahim Ziani

Abel Rousseau and Nik Erykssen

Oliver Wright and Jin Yoo

Tima El-Masri and Audra Smythe-Priestley

Avi Grover and Samar Burman

Max Szczesny and Enzo Principe

Karolina Erykssen and Samar Burman

OOC Info:

Part Two out of Three.

Part two will run for a few days, to allow for everyone to comfortably write their interactions in time; an update will be made both on the blog and discord for subsequent parts.

There is no requirement that people drop previous event threads set during Part 1 — but we encourage everyone to prioritize Part 2. This can be either through new fresh threads, or shifting your Part 1 thread into Part 2.

For characters not involved in the conflict, there are no restrictions to replying to starters (or continuing things) from Part 1, unless they were posted by someone, or are written with someone involved in the conflict. In that case, those starters may no longer be replied to. You’re also free to start any new things with other non-conflict characters as you wish.

If you wish to have any injuries (be them major or minor) or heavy impacting plots happen involving your character, please contact the admins so we can include it into the narrative.

Those in the conflict are encouraged to come up with scenarios where, mid-robbery, one would have the other held hostage. Be it at a hotel room, in some hidden office, or anywhere that is far from view and where there would be plenty to steal. They’re on a mission, after all. As always, if you have trouble coming up with ideas, the admins are always willing to help.

At the end of this post, we offer challenges to the guests. However, those are simply suggested interactions — and even if you choose to write it, your character is not limited to just writing those.

SYNDICATE CHARACTERS:

[ ALL SYNDICATE MEMBERS ARE WEARING NEUTRAL BLACK CLOTHING AND MASKS. IF THEIR CLOTHES WEREN’T NEUTRAL AT THE PARTY, THEN AT THIS POINT THEY WOULD HAVE CHANGED. NOTHING ABOUT THEIR APPEARANCE (THAT THEY CAN CONTROL) SHOULD BE RECOGNIZABLE. EVEN IF ENCOUNTERING SOMEONE THEY HAVE MET BEFORE, THEY ARE TOLD TO KEEP THEIR IDENTITIES SECRET TO THE BEST OF THEIR ABILITIES. ]

For Syndicate members especially, Part 2 should be prioritized so that plots can flow easily.

If you have Part 1 threads, we won’t ask that you drop them, but that you work your way into finishing them — with your characters, above all, keeping in mind that they have a job to do. It might be a night of fun for everyone else, but not them.

From now on, you can only interact with other Syndicate members, or the character you were paired with.

You can write as many mid-robbery threads with your fellow Syndicate members as your heart desires. Interactions amongst them are allowed, and absolutely encouraged!

As far as the rest of the party goes, you may only interact with the character yours was paired with, as one is the other’s hostage.

Your character should be focused in the robbery itself and collecting valuable goods. Anyone they’ve encountered is damage control.

Important: this is meant to be an incredibly secretive and smooth operation. Get in, get out, without causing disturbance. The main party should not have any inkling or knowledge that this is happening.

POINTS AND CHALLENGES:

Syndicate members and conflict volunteers will each earn 20 points for writing their paired threads. (It doesn’t matter if one character ‘wrote’ the starter; both members will be awarded points.)

All remaining characters will earn 20 points for completing the challenges prompted below. They are not mandatory, but we will reward you if you choose to go forth with them.

The points above will be awarded at the end of the event, to account for any starters going unanswered or quickly dropped, as we wish to be as fair as possible.

Surprise! We’re also rewarding conflict volunteers with 30 points for being wonderful team players and allowing us to use their characters for this plot. We adore you and appreciate you, so here’s a small gesture to reflect that!

CHALLENGES:

Jennifer Callaghan recognizes Izaak Walker from his internet presence, and attempts to strike an interview, or even a comment. Izaak knows it’s unadvisable to go forth with it, given all the rum ingested tonight.

Andrea Galán has been avoiding Aaron Keaton, until they cross paths. There’s an inkling or knowledge of her involvement with crime, and tensions rise.

Gideon Hayes is spotted by an off duty Joaquim Borges whilst trying to deal — be it to a random guest, or worst yet, the very detective himself.

Danvir Persaud thinks he recognizes Laith Hassan, from briefly crossing paths in the law-and-lawful world. There’s no reason for a sketch artist and a lawyer to engage however, until now — that they’re both trying to get a vending machine to work.

Renata Cervantes-Müller and Úrsula Villa are both powerful women in their own right — except that they share far different ideals, and defend different people. It’s been easy to avoid one another thus far, until the elevator doors fail, locking them in.

A dentist and the state’s most prominent politician walk into a... bathroom. It’s a classic, slightly awkward, run-in. Except this time, it involves Nicholas Bergeron — and Julian Berkeley.

Jakob Cervantes-Müller is a busy man, and the things keeping him busy aren’t the kindest. For prevention (and future endeavors), he needs a lawyer — and he’s heard Adam Starke is one of the best. What a coincidence, that their drinks just got mixed up at the bar.

Constance Romero, the Cartel’s informant manager, is always on the lookout for future contacts. Like some other select people, she’d heard of Lev Movska’s defection from The Brotherhood — and hell if she isn’t going to try and get all of that knowledge into archive for them. The enemy of my enemy, as they say.

With too much rum in their system, Lola Villarin and Diego Romero end up wandering — testing every other room for unlocked doors. Eventually, they make it into a suite; it’s all fun and games, until the lock won’t allow them back out.

Hazel Arthur and Ryan Fitzgerald barely look at each other, when touching up their make-up in the lobby’s bathroom. But they have to acknowledge each other’s presence when they realize they’re locked in — and Hazel hasn’t heard back from her partner in far too long.

They’d both had the same idea — the hotel’s fire escape as the perfect spot for a smoke break. Hans Starke and Zuleika Sandoval are now forced to share the space (that both claim to have found first).

Bob Bekker and Aera Paek, different positions at different publications. One man with success in his horizon, and a woman who can grant anyone it. It’s a throw-away conversation until the words fact checker come to rise. The best paper, after all, is the most accurate one — would this man do her the favor of failing, in exchange for a brighter future?

Araceli Aguilar suddenly stops Heather Hyeon Seo in the middle of the lobby, with an unwarranted prediction of her future. Even if Heather doesn’t believe in it, it’s intriguing enough that she must hear more.

Rahi Kumar is well known for his love of the sky, preferring to gaze upwards towards the heavens; it is this exact preference, that sends him careening into Andel Kenza, who scurries away from a main party room, clutching what appears to be an empty bottle of rum, a strange substance congealed on its base. The pair stare at another another - a stalemate.

Erin Katz was never a woman to wait for opportunity to simply knock on her door - she prefers to kick it in herself, a stiletto crashing through wooden panels. JJ Baptiste is a man who can make or break you in this city, and with the intriguing wallet she’s just found on the floor, she thinks she’s got enough leverage to earn his ear as he lords over a table in the back of the bar.

Moon Subin is currently scouting the media world, looking for new voices to either support his agenda in the press — or to simply gain insight. It’s unclear which Maureen Keaton could be, yet... but it’s worth a try.

FINAL NOTES

1 — If by any chance your pairing partner, or your challenge partner doesn’t get back to you — please contact the main page and we will rearrange things so that you may still write it! No one will be left without some event fun, we promise.

2 — If you’ve missed the window to volunteer your character for conflict, or you have joined recently and didn’t know about it, you can shoot the main page a message and we will do our very best to include you into the action. Only main page messages, please — as Discord will be hard to keep track of.

3 — As always, the admins are only a message away should you have any questions.

Part 2 interactions are now open. Have fun!

#wb.event #event.hotel #oc rp #crime rp #worldburnrp

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nghread-a · 4 years ago

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Hello, sorry I haven’t been around again - god I’m always doing this - but yeah... I’ve had a really bad stomach bug which has put me in a really bad place for the past few days, but since I’m now getting better slowly, I have decided to come on here and get some replies out.

I’ve also decided to get rid of some of the ocs I’ve added to this blog because it’s clear to me that I have no time to add all of them right now, I’m also going to remove the ones who hasn’t really had much interest in an attempt to get my activity flowing here on this blog.

I’ll write a list of who I am keeping and who I am dropping, so you can then know who I am removing, and if we have any threads with the characters I’m dropping, we can plot with someone else if you’re interested.

Those I am keeping:

Dimitri

Elion

Izrar

Llwynog

Sethos

Pharom

Yuuiko

Those I am dropping:

Amnestria

Andell

Arnon

Casandra

Ciara

Damos

Evelyn

Jericho

Joyce

#ᵒᵘᵗ ᵒᶠ ᶜʰᵃʳᵃᶜᵗᵉʳ — ( ooc )#( I will probably reblog this a couple of times for people to see it but yeah #Sorry for those who I had threads with )

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socialpracticegrouprca · 4 years ago

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Physicality of materials... reference list

Reading list and links from the ‘Working with people and materials across the screen’ with Amy Leung and Katie Spragg (9th February 2021)

Peter Dormer Lecture: Deirdre Figueiredo (Director of Craftspace) https://www.rca.ac.uk/news-and-events/events/peter-dormer-lecture-2021-deirdre-figueiredo-mbe/

Donna Haraway, Staying with the trouble – sympoiesis “a simple word; it means “making-with.” Nothing makes itself; nothing is really autopoietic or self-organizing … Sympoiesis is a word proper to complex, dynamic, responsive, situated, historical systems. It is a word for worlding-with, in company. Sympoiesis enfolds autopoiesis and generatively unfurls and extends it.”

THOMPSON, Tonika Sealy and HARNEY, Stefano. Ground provisions. (2018). Afterall: A Journal of Art, Context and Enquiry. 120-125. Research Collection Lee Kong Chian School Of Business. “Reading together, silently or aloud, belongs with dancing together, cooking together, drinking together, watching movies together, building and cultivating together – and making together. Rather than understanding making as the result of successful social reproduction, we practise it as a temporary emanation, a stepping out without stepping away, where art remains part of the life-giving arts, not a superior comment on them or achievement based on their repro- ductive support. Support is our thing, as Shannon Jackson might say. Support is as Fania and Angela Davis say, the process of creating the society we want right now.”

Diana Coole and Samantha Frost: Introducing the New Materialisms, Introduction: Towards a New Ontology: Matter, Agency and Posthumanism For materiality is always something more than ‘‘mere’’ matter: an excess, force, vitality, relationality, or difference that renders matter active, self-creative, productive, unpredictable. In sum, new materialists are rediscovering a materiality that materializes, evincing immanent modes of self-transformation that compel us to think of causation in far more complex terms; to recognize that phenomena are caught in a multitude of interlocking systems and forces and to consider anew the location and nature of capacities for agency.

One could conclude, accordingly, that ‘‘matter becomes’’ rather than that ‘‘matter is.’’ It is in these choreographies of becoming that we find cosmic forces assembling and disintegrating to forge more or less enduring patterns that may provisionally exhibit internally coherent, efficacious organization: objects forming and emerging within relational fields, bodies composing their natural environment in ways that are corporeally meaningful for them, and subjectivities being constituted as open series of capacities or potencies that emerge hazardously and ambiguously within a multitude of organic and social processes. In this monolithic but multiply tiered ontology, there is no definitive break between sentient and nonsentient entities or between material and spiritual phenomena.

Tara Page: Teaching and Learning with Matter Bodies and things are not as separate as we were once taught, and their intra-relationship is vital to how we come to know ourselves as humans and interact with our environments. The body is pivotal to new materialism, it is a complex intra-action (Barad 2007) of the social and affective, where embodiment is a process of encounters, intra-actions with other bodies (Springgay 2008). Thinking about matter matters—if bodies and things are produced together, intertwined, then ‘things’ and how they act on bodies are co-constitutive of our embodied subjectivity1.

3. Material Pedagogy As I stated previously, through bodies with matter, we are always making, performing and learning. So I put forward that we learn through and with embodied histories and pedagogies but also with matter. It is the intra-actions, the between of bodies and matter that is pedagogic, as ceramic artist De Waal (2011) explains:

Centering the clay, bringing the small ball into perfect reactivity for throwing, involved a ripple of different movements from hand and wrist, an inclination in the head and neck a slight tautening in the shoulders. It was … learning that I could not articulate. (p. 1)

This creative act of learning, of body with matter (clay, wheel, water), is what van der Tuin (2014) asserts is an example of Barad (2003) practices of knowing in being (p. 262).

Hillevi Lenz Taguchi, Going Beyond the Theory/Practice Divide in Early Childhood Education: Introducing an Intra-Active Pedagogy (2010) ‘The child’s hand is grabbing a handful of sand and then slowly letting it go above the bucket. The light wind carries the grains, spreading them out across the surface of the sandbox … the glittering flow of sand, swirling in the wind and catching rays of sun: the grains spreading, dancing, and gently ascending towards the sandpit surface to become part of the greater whole.’ Juliette Kristensen RCA Lecture SLIME: That Hinterland Substance; This Material of the Moment’ RCA: Urgency of the Arts Lecture series. Available at: http://research.gold.ac.uk/id/eprint/27506/

Tim Ingold, On Weaving a Basket

Jane Bennett, Vibrant Matter

Jaroslav Andel , Back to the Sandbox: Art and Radical Pedagogy

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bits-n-bones · 5 years ago

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“A woman in harmony with her spirit is like a river flowing. She goes where she will without pretense and arrives at her destination prepared to be herself and only herself.” - Maya Andelou #bitsandbonesofinstagram #pagans #paganritual #pagancrafts #wicca #paganism #paganart #witchcraft #witchesofinstagram #witchpower #witchesofinstagram🔮🌙 #warlocksofinstagram #witchesandwarlocks https://www.instagram.com/p/CA5xcTogC4p/?igshid=4a1zykquv9cf

#bitsandbonesofinstagram #pagans #paganritual #pagancrafts #wicca #paganism #paganart #witchcraft #witchesofinstagram #witchpower #witchesofinstagram🔮🌙#warlocksofinstagram #witchesandwarlocks

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mariebenz · 5 years ago

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Why Do the Identical-Looking Brain Hemispheres Act Differently?

MedicalResearch.com Interview with:

Dr. Labrie Dr. Viviane Labrie, PhD Dr. Labrie is an associate professor in Van Andel Institute’s Center for Neurodegenerative Science, where she studies Parkinson’s, Alzheimer’s and other neurological diseases. MedicalResearch.com: What is the background for this study? Response: One of the most puzzling and persistent mysteries in neuroscience has been why some people are “right-brained” while others are “left-brained.” The two sides of the brain have different jobs. The left side is analytic and problem-solving, while the right side manages creativity and artistic talents. But despite their differences, the two sides are composed of the same cell types — essentially, brain neurons and their support cells. In this study, we sought to understand how it is possible for these cells to behave completely differently depending on what hemisphere they’re located in. We also wanted to examine the reasons behind asymmetry in Parkinson’s disease; that is, why Parkinson’s symptoms typically start on one side of the body before the other. This asymmetry in neurodegeneration and symptoms in patients is one of the biggest unsolved puzzles in the Parkinson’s disease field — why do brain cells in one hemisphere begin dying before brain cells in the other hemisphere? MedicalResearch.com: What are the main findings? What are the implications for Parkinson's disease? Response: We found that hemispheric differences are related to molecular modifications on DNA that help determine the “day job” of a brain cell. Two cells that look totally identical can behave differently because of the molecular, or epigenetic, marks on the cell’s DNA. Each cell in the brain has the same genes, but it is epigenetics that dictate whether those genes are switched “on” or “off.” Our team found numerous epigenetic differences between the hemispheres of healthy brains that are linked to variations in gene activity. This is important to our fundamental understanding how our brain is built and works. It may also contribute to understanding the asymmetric nature of Parkinson’s disease. In the same study, we found that asymmetry in Parkinson’s disease is associated with variations in these epigenetic marks in brain neurons that affect brain development, chemical signaling and immune activation. In other words, epigenetic abnormalities on one side of the brain could make that hemisphere more susceptible to the processes that cause the death of brain cells in Parkinson’s. MedicalResearch.com: What should readers take away from your report? Response: Both hemispheres of the brain may, at first glance, look identical in structure — comprising brain neurons and their helper cells — but molecular-level patterns in the cell’s DNA can cause vastly different behaviors in each hemisphere and enable asymmetry in the brain. As it relates to Parkinson’s disease, the brain appears to be wired at the molecular level such that one hemisphere is more vulnerable to neurogenerative processes than the other. The differences in cell death across hemispheres leads to the appearance of the disease’s hallmark symptoms, such as tremors, on one side of the body before the other MedicalResearch.com: What recommendations do you have for future research as a result of this work? Response: We are already looking at how the molecular differences that may cause brain asymmetry come into play in other diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS or Lou Gehrig’s disease), multiple sclerosis and schizophrenia. Understanding how hemispheric differences in the brain affect disease progression sheds light on underlying factors of the disease, which has huge potential for translating into new therapeutic strategies. Disclosures: Other authors include Peipei Li, Ph.D., Elizabeth Ensink, Sean Lang, Lee Marshall, Ph.D., and Meghan Schilthuis of Van Andel Institute; and Jared Lamp, Ph.D., and Irving Vega, Ph.D., of Michigan State University College of Human Medicine. The Flow Cytometry Core, Bioinformatics and Biostatistics Core and Pathology and Biorepository Core at Van Andel Institute and Integrated Mass Spectrometry Unit at Michigan State University also contributed to this work. Brain tissue was provided by the Parkinson’s UK Brain Bank, the NIH NeuroBioBank and the Michigan Brain Bank. This work was supported by Van Andel Institute. Labrie is supported by the U.S. Army Medical Research Materiel Command through the Parkinson’s Research Program Investigator-Initiated Research Award under award no. W81XWH1810512. Opinions, interpretations, conclusions and recommendations are those of the author and are not necessarily endorsed by the U.S. Army. Labrie also is supported by the National Institute of Neurological Disorders and Stroke of the National Institutes of Health under Award Number R21NS112614 and by Michigan State University through the Gibby & Friends vs. Parky Parkinson’s Disease Research Award. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or other granting organizations. Citation: Peipei Li, Elizabeth Ensink, Sean Lang, Lee Marshall, Meghan Schilthuis, Jared Lamp, Irving Vega, Viviane Labrie. Hemispheric asymmetry in the human brain and in Parkinson’s disease is linked to divergent epigenetic patterns in neurons. Genome Biology, 2020; 21 (1) DOI: 10.1186/s13059-020-01960-1 The information on MedicalResearch.com is provided for educational purposes only, and is in no way intended to diagnose, cure, or treat any medical or other condition. Always seek the advice of your physician or other qualified health and ask your doctor any questions you may have regarding a medical condition. In addition to all other limitations and disclaimers in this agreement, service provider and its third party providers disclaim any liability or loss in connection with the content provided on this website. Read the full article

#healthcare #medicalresearch #neurology #Parkinson'sDisease #VAInstitute

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chaoticbeauty4216-blog · 7 years ago

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Considering it was my first, official concert, Winter Jam 2018 was a blast!! Got to spend a day with my friends and then had an awesome girls night out! Much needed from the distractions of current struggles! The Lord was flowing out of the artists performing tonight! A much needed night of just pure, raw, worship in a space full of believers! #girlsnight #winterjam2018 #lonlybutnotalone (at Van Andel Arena Grand Rapids, Michigan)

#lonlybutnotalone #winterjam2018 #girlsnight

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responsivesites · 5 years ago

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New Post has been published on Website Design Naples Florida Webmaster

New Post has been published on https://vinbo.com/wordpress-5-4-adderley/

WordPress 5.4 “Adderley”

Here it is! Named “Adderley” in honor of Nat Adderley, the latest and greatest version of WordPress is available for download or update in your dashboard.

Say hello to more and better.

More ways to make your pages come alive. With easier ways to get it all done and looking better than ever—and boosts in speed you can feel.

Welcome to WordPress 5.4

Every major release adds more to the block editor.

More ways to make posts and pages come alive with your best images. More ways to bring your visitors in, and keep them engaged, with the richness of embedded media from the web’s top services.

More ways to make your vision real, and put blocks in the perfect place—even if a particular kind of block is new to you. More efficient processes.

And more speed everywhere, so as you build sections or galleries, or just type in a line of prose, you can feel how much faster your work flows.

Two new blocks. And better blocks overall.

Two brand-new blocks: Social Icons and Buttons make adding interactive features fast and easy.

New ways with color: Gradients in the Buttons and Cover block, toolbar access to color options in Rich Text blocks, and for the first time, color options in the Group and Columns blocks.

Guess a whole lot less! Version 5.4 streamlines the whole process for placing and replacing multimedia in every block. Now it works the same way in almost every block!

And if you’ve ever thought your image in the Media+Text block should link to something else—perhaps a picture of a brochure should download that brochure as a document? Well, now it can.

Cleaner UI, clearer navigation—and easier tabbing!

Clearer block navigation with block breadcrumbs. And easier selection once you get there.

For when you need to navigate with the keyboard, better tabbing and focus. Plus, you can tab over to the sidebar of nearly any block.

Speed! 14% faster loading of the editor, 51% faster time-to-type!

Tips are gone. In their place, a Welcome Guide window you can bring up when you need it—and only when you need it—again and again.

Know at a glance whether you’re in a block’s Edit or Navigation mode. Or, if you have restricted vision, your screen reader will tell you which mode you’re in.

Of course, if you want to work with the very latest tools and features, install the Gutenberg plugin. You’ll get to be the first to use new and exciting features in the block editor before anyone else has seen them!

Your fundamental right: privacy

5.4 helps with a variety of privacy issues around the world. So when users and stakeholders ask about regulatory compliance, or how your team handles user data, the answers should be a lot easier to get right.

Take a look:

Now personal data exports include users session information and users location data from the community events widget. Plus, a table of contents!

See progress as you process export and erasure requests through the privacy tools.

Plus, little enhancements throughout give the privacy tools a little cleaner look. Your eyes will thank you!

Just for developers

Add custom fields to menu items—natively

Two new actions let you add custom fields to menu items—without a plugin and without writing custom walkers.

On the Menus admin screen, wp_nav_menu_item_custom_fields fires just before the move buttons of a nav menu item in the menu editor.

In the Customizer, wp_nav_menu_item_custom_fields_customize_template fires at the end of the menu-items form-fields template.

Check your code and see where these new actions can replace your custom code, and if you’re concerned about duplication, add a check for the WordPress version.

Blocks! Simpler styling, new APIs and embeds

Radically simpler block styling. Negative margins and default padding are gone! Now you can style blocks the way you need them. And, a refactor got rid of four redundant wrapper divs.

If you build plugins, now you can register collections of your blocks by namespace across categories—a great way to get more brand visibility.

Let users do more with two new APIs: block variations and gradients.

In embeds, now the block editor supports TikTok—and CollegeHumor is gone.

There’s lots more for developers to love in WordPress 5.4. To discover more and learn how to make these changes shine on your sites, themes, plugins and more, check the WordPress 5.4 Field Guide.

The Squad

This release was led by Matt Mullenweg, Francesca Marano, and David Baumwald. They were enthusiastically supported by a release squad:

Editor Tech: Jorge Filipe Costa (@jorgefelipecosta)

Editor Design: Mark Uraine (@mapk)

Core Tech: Sergey Biryukov (@sergeybiryukov)

Design: Tammie Lister (@karmatosed)

Docs Coordinator: JB Audras (@audrasjb)

Docs & Comms Wrangler: Mary Baum (@marybaum)

The squad was joined throughout the release cycle by 552 generous volunteer contributors who collectively worked on 361 tickets on Trac and 1226 pull requests on GitHub.

Put on a Nat Adderley playlist, click that update button (or download it directly), and check the profiles of the fine folks that helped:

0v3rth3d4wn, 123host, 1naveengiri, Aaron Jorbin, Abhijit Rakas, abrightclearweb, acosmin, Adam Silverstein, adamboro, Addie, adnan.limdi, Aezaz Shaikh, Aftab Ali Muni, Aki Björklund, Akib, Akira Tachibana, akshayar, Alain Schlesser, Albert Juhé Lluveras, Alex Concha, Alex Mills, AlexHolsgrove, alexischenal, alextran, alishankhan, allancole, Allen Snook, alpipego, Amir Seljubac, Amit Dudhat, Amol Vhankalas, Amr Gawish, Amy Kamala, Anantajit JG, Anders Norén, Andrés, Andrea Fercia, Andrea Tarantini, andreaitm, Andrei Draganescu, Andrew Dixon, Andrew Duthie, Andrew Nacin, Andrew Ozz, Andrew Serong, Andrew Wilder, Andrey Savchenko, Andy Fragen, Andy Meerwaldt, Andy Peatling, Angelika Reisiger, Ankit Panchal, Anthony Burchell, Anthony Ledesma, apedog, Apermo, apieschel, Aravind Ajith, archon810, arenddeboer, Ari Stathopoulos, Arslan Ahmed, ashokrd2013, Ataur R, Ate Up With Motor, autotutorial, Ayesh Karunaratne, BackuPs, bahia0019, Bappi, Bart Czyz, ben.greeley, benedictsinger, Benjamin Intal, bibliofille, bilgilabs, Birgir Erlendsson, Birgit Pauli-Haack, BMO, Boga86, Boone Gorges, Brad Markle, Brandon Kraft, Brent Swisher, Cameron Voell, Carolina Nymark, ceyhun0, Chetan Prajapati, Chetan Satasiya, Chintesh Prajapati, Chip Snyder, Chris Klosowski, Chris Trynkiewicz (Sukces Strony), Chris Van Patten, Christian Sabo, Christiana Mohr, clayisland, Copons, Corey McKrill, crdunst, Csaba (LittleBigThings), Dademaru, Damián Suárez, Daniel Bachhuber, Daniel James, Daniel Llewellyn, Daniel Richards, Daniele Scasciafratte, daniloercoli, Darren Ethier (nerrad), darrenlambert, Dave Mackey, Dave Smith, daveslaughter, DaveWP196, David Artiss, David Binovec, David Herrera, David Ryan, David Shanske, David Stone, Debabrata Karfa, dekervit, Delowar Hossain, Denis Yanchevskiy, Dhaval kasavala, dhurlburtusa, Dilip Bheda, dingo-d, Dion Hulse, dipeshkakadiya, djp424, dominic_ks, Dominik Schilling, Dotan Cohen, dphiffer, dragosh635, Drew Jaynes, eclev91, ecotechie, eden159, Edi Amin, edmundcwm, Eduardo Toledo, Ella van Durpe, Ellen Bauer, Emil E, Enrique Piqueras, Enrique Sánchez, equin0x80, erikkroes, Estela Rueda, Fabian, Fabian Kägy, Fahim Murshed, Faisal Alvi, Felipe Elia, Felipe Santos, Felix Arntz, Fernando Souza, fervillz, fgiannar, flaviozavan, Florian TIAR, Fotis Pastrakis, Frank Martin, Gal Baras, Garrett Hyder, Gary Jones, Gary Pendergast, Gaurang Dabhi, George Stephanis, geriux, Girish Panchal, Gleb Kemarsky, Glenn, Goto Hayato, grafruessel, Greg Rickaby, Grzegorz Ziółkowski, Grzegorz.Janoszka, Gustavo Bordoni, gwwar, hamedmoodi, hAmpzter, happiryu, Hareesh Pillai, Harry Milatz, Haz, helgatheviking, Henry Holtgeerts, Himani Lotia, Hubert Kubiak, i3anaan, Ian Belanger, Ian Dunn, ianatkins, ianmjones, IdeaBox Creations, Ihtisham Zahoor, intimez, Ipstenu (Mika Epstein), Isabel Brison, ispreview, Jake Spurlock, Jakub Binda, James Huff, James Koster, James Nylen, jameslnewell, Janki Moradiya, Jarret, Jasper van der Meer, jaydeep23290, jdy68, Jean-Baptiste Audras, Jean-David Daviet, Jeff Bowen, Jeff Ong, Jeff Paul, Jeffrey Carandang, jeichorn, Jenil Kanani, Jenny Wong, jepperask, Jer Clarke, Jeremy Felt, Jeremy Herve, Jeroen Rotty, Jerry Jones, Jessica Lyschik, Jip Moors, Joe Dolson, Joe Hoyle, Joe McGill, Joen Asmussen, John Blackbourn, John James Jacoby, John Watkins, Jon, Jon Quach, Jon Surrell, Jonathan Desrosiers, Jonathan Goldford, Jonny Harris, Jono Alderson, Joonas Vanhatapio, Joost de Valk, Jorge Bernal, Jorge Costa, Josepha Haden, JoshuaWold, Joy, jqz, jsnajdr, Juanfra Aldasoro, Julian Weiland, julian.kimmig, Juliette Reinders Folmer, Julio Potier, Junko Nukaga, jurgen, justdaiv, Justin Ahinon, K. 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S., vortfu, waleedt93, WebMan Design | Oliver Juhas, websupporter, Weston Ruter, William Earnhardt, William Patton, wpgurudev, WPMarmite, wptoolsdev, xedinunknown-1, yale01, Yannicki, Yordan Soares, Yui, zachflauaus, Zack Tollman, Zebulan Stanphill, Zee, and zsusag.

Many thanks to all of the community volunteers who contribute in the support forums. They answer questions from people across the world, whether they are using WordPress for the first time or since the first release. These releases are more successful for their efforts!

Finally, thanks to all the community translators who worked on WordPress 5.4. Their efforts bring WordPress fully translated to 46 languages at release time, with more on the way.

If you want to learn more about volunteering with WordPress, check out Make WordPress or the core development blog.

Original source: https://wordpress.org/news/2020/03/adderley/

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badfoodcv · 5 years ago

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Hur fungerar Bleka Tänderna Hemma Med Bakpulver?

Med assistans itu tandblekningsgel kan du bleka dina garnityr antingen hemma eller hos tandläkaren. Metoden innebär att den blekningsgel som applicerats på dina garnityr aktiveras tillsammans bistånd itu laserljus inom upprepade intervaller. Att bleka tänderna hemma med salt befinner sig någon väl hållbar huskur när hane befinner sig ute efter att erhålla en aning vitare garnityr. Tandblekning tillsammans salt / himalayasalt / havssalt. Tandblekning hemma - hurdan funkar det? En bit upplever ytterlighet pina när dom utför tandblekning eller när dom tillåts blekmedel på tandköttet. Har man mager emalj lyser tandens invärtes del (det gulare dentinet) igenom mer varför likadan "vithet" som den som äger tjockare emalj aldrig kan uppnås. Men en andel antar att dessa inte fungerar, inte med att dom snarare skulle produkt något utav lura samt båg produkter. Du skulle tydligen inte önska att världen ser dem! Sodium Bikarbonat skänker långvarigt friskare andedräkt samt stöder åt att hindra sjukdomar inom tandköttet . Beconfidents förfarande bygger på en sammansättning utav rengörande substanser (surfaktant, Surface Active Agents) och aktivt blekande 32% sodium bikarbonat.

Hur man hanterar varje Bleka Tänder Bikarbonat utmaning med lätthet med hjälp av dessa tips

Till avvikelse från väte-peroxid som kan tillhandahålla obehagliga ilningar samt smärtor i tänderna befinner sig våra aktiva substanser skonsamma samt totalt gratis från biverkningar. Många tandläkare befinner sig negativt inställda mot Listerin som mot diskrepans mot Flux innehåller mest baktericid medel samt uppemot ingen flour. En tandläkare inneha också flera hänvisning som du måste åtfölja. Det befinner sig otaliga som försöker sig gällande prylar som kokosolja, bakpulver alternativt bikarbonat, såsom karl kan studera försåvitt på nätet. Därför att få vitare tänder med bakpulver använder du dig av ett s.k. hemgjord tandblekning. Det befinner sig inte en på sekunden tandblekningsmetod inte med ett tandfasad, alternativt porslinsfasad - gjorda utav porslinsskal som klistras fastsatt gällande tandens fasad därför att hemlighålla ytterst missfärgade alternativt skadade tänder. Blekning utav naturliga garnityr är en säkert samt ledigt taktik såsom kan bidraga en ljusare samt fräschare yttre villig tänderna. Man skall fullständig lätt rykta tänderna med pulvret och efter två dagar allaredan ska man uppmärksamma resultat! Det finns tandläkare och doktor som tycker att mödrar skall vänta med tandblekning tills de inte längre ammar.

Det kanhända billigaste sättet att bleka tänderna görs igenom Air flow, någon förfaringssätt som används hos tandläkare. Det billigaste priset stäv Whitenow 5 Min Touch-Up Dental Whitening Kit för tillfället befinner sig 299 kr. Har du städse drömt om ett sann Hollywoodleende befinner sig tandfasader något förut dej! 7 huskurer därför att bleka missfärgade garnityr naturligt Hur bleker ni emedan tänderna skonsamt samt effektivt? Kycklingbröst inom lergryta - huskur bleka tänder. Världens enklaste huskur - såhär får du vita tänder med blott 1 komponent! Denna huskur tar emellertid enkom dän inte ens utspelar försåvitt att bleka. Men att hela tiden bleka tänderna hos någon salong kan bli dyrt i längden samt tillika används ofta kemikalier som ej befinner sig enastående stäv dig. Med denna procedur undviker du dyra kemikalier. En mycket oproblematisk tillvägagångssätt att bleka tänderna, såsom förr varenda vanlig tidvis övrigt USA. Jag kommer aldrig mer förbruka något annat till kärna barr armé tittar centrum barr ut postumt 2 veckor av bikarbonat-byk. Detta brukar ströva slut i ett par veckor.

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cataclizard · 8 years ago

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I keep remembering this drabble thing I’ve had in my files for a while, and I was kinda hesitating on posting it due to wanting to draw a thing for it but [LOUD SHRUGGING] Featuring @alphahusk‘s Astraea because obvs :y

-Invisible-

The streets of Suramar were quiet, as one could expect when the sun finally set. However, it had proven itself to be a restless city, making the sudden, vacant streets seem unusual... if not a bit unnerving. One lone figure walked along the back alleys of the city, clutching the strap of his shoulder bag as his glowing gaze wandered the surroundings. The figure in question was not as he appeared, however, being one of the many 'Outlanders' bearing a Nightborne disguise so he could traverse the city; it was not without its faults, but it was enough to slip past most citizens without so much as a second glance. It was more than enough comfort for Andel keep his pace steady, turning a random corner and finding himself in an open garden of sorts. Looking around, he felt a light breeze flow past him, causing the willow branches overhead to sway and emit a gentle, chiming sound. Glancing up, he felt a burst of awe at the twinkling 'stars' that were nestled close to the inner curve of the canopy. Briefly clenching his jaw, the disguised half-elf returned his attention to the ground, checking the area for any guards. He approached one of the many stone benches strewn about the area, opening his satchel and peering at its contents; some crystalized, ancient mana he had gathered for the struggling Nightborne that he came across, along with a whole assortment of flora that he had found in Suramar. Though he could admit the latter was moreso for research and sharing with his allies in this city. As he went about separating the differing flowers, roots, and general supplies, Andel's peripheral vision made him take notice of the fountain to his immediate right, pausing from his sorting to look more fully at the shimmering water. The disguised half-elf felt a cool, sharp pang of realization strike the very core of his being as his reflection became more clear...

In the water, he could see someone that only vaguely resembled him. No horns sprouting from his head, no snout-like nose, no wings... the triangular markings were still there, but they had become more fanciful, with a distinct shimmer that often highlighted them in certain lighting. Pitch black hair was now a shimmering off-white, but otherwise remained the same, pulled back and gathered in a ponytail to keep it out of the way. Andel blinked, looking down at himself and seeing no signs of his clawed, three-digit hands; but in their place were normal elven ones, five fingers and mildly calloused. It took a physical effort for the half-elf to breathe again, his gaze returning to the water. Was this what it was like to be... normal? Such a thought was always fleeting for someone like him, living with the double-edged blade of being both the child of a cross faction couple, and being sired by the Betrayer himself. Always one or the other when it came to the basis of people's wary looks and gossiping mutters, and he had gotten so used to simply ignoring them that the sudden lack of it had barely registered until now. The feeling of being so... unnoticed felt alien to him. Creeping anxiety manifested as he felt the urge to leave, slip through one of Oculus' portals so he could shed the disguising spell and feel comfortable in his skin again-

"Andel...?" a new voice cut through his increasingly racing thoughts, making him visibly wince before looking towards the source of the voice. His tense self easing slightly at the familiar face. "Astraea! Ah... what're you doing here?" he asked, his voice the one thing that remained wholly unchanged. The Nightborne fidgeted with the fabric of her outfit as he noticed her wandering eyes, wondering just how clear his newfound turmoil was to an outside viewer, "You um," she paused, her free hand loosely gesturing towards the open satchel of plants, "You mentioned how you could get flora from outside of the city, and that you wanted to show me some of it when you returned, so..."

Andel watched her shrug slightly, then cleared his throat and haphazardly set out the rest of the plants he'd gathered, doing his best to calm himself and his trembling hands, "Right, right. Sorry I'm just..." a soft huff of frustration left his lips, "Distracted..."

The half-elf hadn't realized the Nightborne had stepped closer, sitting opposite of him on the stone bench and resting her folded hands in her lap, though her eyes were no longer on the dried flowers between them. Her head cocked to the side slightly, glowing eyes scanning his face with a sudden, newfound intensity, "Is something troubling you?"

Her inquiry made Andel tense again, this time in a more subtle fashion. How could he word it? Should he even say anything about it? A small thought slipped through and to the forefront of his mind... the two had formed a surprising companionship since Suramar's barrier had been torn down, and it had shown Andel places in Suramar he never would have ever known had it not been for her. Still, he had no way of knowing how Astraea would view him if he admitted to using this magic-based disguise. With the current societal state, being skeptical was often the best route for survival...

Andel mirrored her gesture, letting his hands rest on his lap as he constructed his thoughts, "Have you... have you ever had a moment where you felt invisible? Not in a negative way, mind you, just... having this sense of... belonging, I guess?" He shifted his weight slightly, reaching up to scratch an itch on his cheek before he thought to continue, "I've always felt a bit out of place, and I don't know what it is but... something about today made me realize how it felt to be a part of a crowd, even though I'd been in them hundreds of times before."

The Nightborne across from him bobbed her head, a moment of silence floating between them as she turned her attention to the nearby willow that hung overhead, "I suppose I have. Living in the Nighthold, there's a sort of... disconnect, when you step outside and walk among the rest of the city," Astraea's gaze returned to him, "It's liberating in it's own way, but sometimes you just can't shake the feeling of 'I don't think I'm supposed to be here' even if people are paying you no mind otherwise. But..."

The silence captured Andel's attention, and with it, he could have sworn he saw a sense of... sadness in her eyes? Though he often tried to avoid presuming one's emotions and thoughts, this seemed unusual, even for the Nightborne. His pointed ears lowered as the silence persisted, reaching one hand up and pausing... then lowering it and instead leaning to the side, within her peripheral vision and deciding to ease his wary 'survival' skills for a bit,

"I know I don't talk about it often, but I've actually been outside of Suramar City." he said, his voice taking on a more gentle tone. He watched Astraea blink, brows knitting together as she looked to him again, "The actual city?"

He nodded, "That's how I've been getting these flowers, and maybe... maybe someday, when all of this is over, you can come with me! If... if you'd like to, of course." The Nightborne nodded with him, looking down at her hands as she considered this proposal of his. "I... I would love to." she said finally, a rare smile peeking through as her shoulders bunched up with mirth.

And in that moment, Andel felt a sudden, glowing warmth in his chest as he saw her small but oh so significant reaction. He couldn't recall right away seeing her so genuinely happy looking, but deep down, the half-elf wanted to help her smile again and again... she deserved that much, at the very least.

#hey looky I can kinda write #also if any of the stuff seems OOC for the Starleaf lemme know and I'll scrap this and redo it :'D #Andel Proudpelt #Astraea #aka Andel Still Has Image Issues: The Story

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beatmyaudio · 5 years ago

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Ei Song Lyrics – Nelly

Ei Song Lyrics

Ei Song Lyrics From Popular Hollywood Artist Nelly from Album.

This song is sung by singer ” Nelly ” in Year 2001.

Lyrics of Ei :

uh wait a minute now can you hear me out there lunatics is yall ready let me hear yaima sucker for cornrows and manicured toes hey fendi capri pants and parasucos alright passadity city with one or two throws im dropping outta high school straight into the pros who knows i know that i love it when you make your knees touch your elbows and break it down low to the flow there you go now throw it on me slow and every time i bust a rhyme baby give me some more you say you like that when i hit it from behind and ill be right back yea thats my very next line i use it time after time when im speaking my mind its no matter if im shooting game to a pigeon and dime i ask you who that is talking that shit about the tics somebody probably jealous cause they bitch got hit but nobody else dropping shit like dis should we apologize fuck em just leave em pissed heyandele andale moma ei ei uh oh whats poppin tonight andele andale moma ei ei uh oh if the head right nelly there every nightandele andale moma ei ei uh oh whats poppin tonight andele andale moma ei ei uh oh if the head right nelly there every nightwe can go to the break of dawn nigga money long nigga go fast up the skirt to talk to the thong nigga some say im wrong fuck it im grown nigga if you aint bout money then best be gone nigga im flashy uh double takes when you walk past me nasty dont be scared boo go ahead and ask me i drive fasty call me jeff gordon in a black ss wit a navigation see the black blazion something smells amazing i gotta chick rolling up half black and asian another one paging telling me to come over her husband on vacation and left her home alone i used the v12 powers weight loss powers from phat farm to iceberg slim in one shower get a room in trump towers just to hit for 3 hours get the bitch up out the room cause she used the word oursandele andale moma ei ei uh oh whats poppin tonight andele andale moma ei ei uh oh if the head right nelly there every nightandele andale moma ei ei uh oh whats poppin tonight andele andale moma ei ei uh oh if the head right nelly there every nightthey got a smash mouth of a whole ounce of that sticky watch my hands under a gold spout feeling icky let go off in a hoes mouth i aint picky start fronting when the shows out what ya mean 20 inches when they roll out come and get me big faces when they fold out is ya wit me dont make me pull that 44 out i keep it close when i the go out then i slide up in an esclade me and e getting solid like the ice capades from heat frosty roger the rabbit than bugsy you understand me wrapped crisp like mummysif you compare me to your local grocery then youll see i got more carrots than aisle d more bread than aisle e you can bag and scan me sure like al be you can meet tha tics in maui heyandele andale moma ei ei uh oh whats poppin tonight andele andale moma ei ei uh oh if the head right nelly there every nightandele andale moma ei ei uh oh whats poppin tonight andele andale moma ei ei uh oh if the head right nelly there every night

Ei Song Lyrics

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Lyrics, Edit, Ei, English, Hollywood, Nelly from WordPress https://ift.tt/3hxu1Ed via IFTTT

#IFTTT #WordPress

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scienceblogtumbler · 5 years ago

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Being right-brained or left-brained comes down to molecular switches

Scientists may have solved one of the most puzzling and persistent mysteries in neuroscience: why some people are “right-brained” while others are “left-brained.”

The answer lies in how certain genes on each side of the brain are switched “on” and “off” through a process called epigenetic regulation. The findings may explain why Parkinson’s disease and other neurological disorders frequently affect one side of the body first, a revelation that has far-reaching implications for development of potential future treatments.

The study was led by Van Andel Institute’s Viviane Labrie, Ph.D., and published in the journal Genome Biology.

“The mechanisms underlying brain asymmetry have been an elephant in the room for decades,” Labrie said. “It’s thrilling to finally uncover its cause, particularly given its potential for helping us better understand and, hopefully one day, better treat diseases like Parkinson’s.”

Each cell in the brain has the same genes but it is epigenetics that dictate whether those genes are switched “on” or “off.” Labrie and her collaborators found numerous epigenetic differences between the hemispheres of healthy brains that are linked to variations in gene activity. Notably, these differences, or asymmetry, could make one side of the brain more vulnerable to neurological diseases.

For example, epigenetic abnormalities on one side of the brain could make that hemisphere more susceptible to the processes that cause the death of brain cells in Parkinson’s. The differences in cell death across hemispheres leads to the appearance of the disease’s hallmark symptoms, such as tremor, on one side of the body before the other. As the disease progresses, symptoms on the side first affected often are more severe than symptoms on the other side of the body.

The findings also give scientists a vital window into the various biological pathways that contribute to symptom asymmetry in Parkinson’s, including brain cell development, immune function and cellular communication.

“We all start out with prominent differences between the left and right sides of our brains. As we age, however, our hemispheres become more epigenetically similar. For Parkinson’s, this is significant: people whose hemispheres are more alike early in life experienced faster disease progression, while people whose hemispheres were more asymmetric had slower disease progression,” Labrie said. “Many of these changes are clustered around genes known to impact Parkinson’s risk. There is huge potential to translate these findings into new therapeutic strategies.”

Labrie is already starting to look at this phenomenon in other neurological diseases like Alzheimer’s.

The study is one of the first to parse the molecular causes of brain asymmetry. Early research on the left versus right brain was conducted in the mid-20th century by Roger Sperry, whose groundbreaking work with split-brain patients earned him a Nobel Prize.

Authors include Peipei Li, Ph.D., Elizabeth Ensink, Sean Lang, Lee Marshall, Ph.D., and Meghan Schilthuis of Van Andel Institute; and Jared Lamp, Ph.D., and Irving Vega, Ph.D., of Michigan State University College of Human Medicine. The Flow Cytometry Core, Bioinformatics and Biostatistics Core and Pathology and Biorepository Core at Van Andel Institute and Integrated Mass Spectrometry Unit at Michigan State University also contributed to this work. Brain tissue was provided by the Parkinson’s UK Brain Bank, the NIH NeuroBioBank and the Michigan Brain Bank.

This work was supported by Van Andel Institute.

Labrie is supported by the U.S. Army Medical Research Materiel Command through the Parkinson’s Research Program Investigator-Initiated Research Award under award no. W81XWH1810512. Opinions, interpretations, conclusions and recommendations are those of the author and are not necessarily endorsed by the U.S. Army. Labrie also is supported by the National Institute of Neurological Disorders and Stroke of the National Institutes of Health under Award Number R21NS112614 and by Michigan State University through the Gibby & Friends vs. Parky Parkinson’s Disease Research Award. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or other granting organizations.

source https://scienceblog.com/515554/being-right-brained-or-left-brained-comes-down-to-molecular-switches/

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mariebenz · 5 years ago

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Why Do the Identical-Looking Brain Hemispheres Act Differently?

MedicalResearch.com Interview with:

#healthcare #medicalresearch #neurology #Parkinson'sDisease #VAInstitute

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