#metabolic alkalosis

[mcatmemoranda]

Signs to monitor with CHF: JVD, pitting edema, crackles, urine output, weight

Every 1 increase in bicarb equals an increase of CO2 by 10. Pts who are heavier need more prednisone. We have a pt with BMI >50, and she needs 60 mg prednisone for COPD exacerbation.

[duckyfann9871]

GUESS WHO PASSED RENAL BLOCK WHOOP

[dipperscavern]

hiiii! the anon who requested the Mike x fem!reader fic here. please don't apologise, I can totally understand😭😭 the show's too addictive, I binged watched the first few seasons really quick too, you can take your time🫶🏾

HII IM SO SORRY FHIS TOOK SO LONG GRR. honestly, i really struggled w this 😭 i didn’t make it very long or defined (i wanted this to set the tone of their relationship), and i left it pretty open ended (on purpose) so it could be built off of in other continuations as maybe a clientsdaughter!reader 🙂‍↕️thank u sm for the ask & i hope u enjoy!! (this is ass)

mike ross x fem!clientsdaughter!reader

mike had learned a countless amount of knowledge since joining the firm. how to talk to people, how to negotiate, how to work, how to win. along with this, he also learned the workings of the office itself — more so the people that were in it.

kyle talks to his girlfriends throughout the day. it’s often mike can catch him leaned back in his chair, not-so-discreetly checking his phone, eyebrows raising as he clicks on the selfie he was sent.

louis keeps his favorite breakfast bars in the top cabinet. rachel chews her lip when she’s thinking. the fax machine only listens to donna — don’t mention if harvey’s having a bad hair day, he knows.

oh. and don’t sleep with clients.

not getting involved with clients was a general rule of thumb. according to harvey, the less emotion involved, the better. even so, harvey himself was guilty of sleeping with a few clients — after business was done, of course. but that was different. harvey was harvey, and mike was a first year associate, already tap dancing on thin ice. he could absolutely not afford to break any rules — no matter how unspoken they might be.

truly, it was all going fine. until he met you.

you & your father are in the racehorse industry. famous for the record breaking times your horses submit (& the world-class conditions they’re always in), thousands come to the races to bet on them. your family has been breeding, training, and racing horses for decades, and your father loves his job. there’s only one issue.

he’s currently being sued for “wrongful termination” by an ex employee. the employee mistreated multiple horses during his time working for you & your father. once you both found out, he was gone.

now, 4 months later, when your most famous horse “knights honor” has died, the employee is claiming the horse was milkshaked before his races (he was not).

“Milkshaked? What the hell is that?”

harvey’s voice carried through his office as jessica presented the case to him & mike. your father was a friend to her, and it was important that harvey got this done. mike remembers the article he read years ago on racehorses when knights honor won his first championship.

“In the context of horse racing and illegal substances, a milkshake is any compound or combination of compounds administered to a horse, pre-race, for the purpose of causing.. metabolic alkalosis of the blood and extracellular fluid of that horse. Although, a previous widely used method to ensure placing times, milkshakes are a prohibited practice on race day in all U.S. jurisdictions.”

harvey and jessica exchange looks between themselves & mike. they're about to raise questions when donna's voice crackles through harvey's phone.

"Translation: Its when the horses are given a “milkshake” of different drugs before a race. It can kill fatigue and improve their endurance."

all heads look down to the phone, then at donna's desk. donna's already looking their way, of course, and she swallows under their field of vision. she shrugs.

"What? I can't.. watch tv?"

she abruptly puts the phone down, turning her chair around to type on her computer. jessica clears her throat.

"Tom is an old friend. He's genuine."

harvey interrupts. "You need me to make it go away.”

“No. This could tarnish his entire reputation… his life’s work. I need you to kill this thing in its tracks. Get it done.”

with that, jessica turns & exists the office. harvey sighs, skimming over the case file jessica dropped on his desk. he looks at mike.

“Find the daughter. Find out everything — previous arrests, divorces, a stolen tangerine from publix- I wanna know about it.”

mike nods, offering a-

“Yes, captain,”

(which makes harvey give him an exasperated look) before he retreats back to his cubicle, moving to start his manhunt. donna winks as he passes her desk.

꧁——————————————————꧂

“No, he doesn’t.”

you can sense the presence of the associate approaching behind you. you quickly thank the man working the stand as he hands you your pretzel, and you turn to face harvey’s right-hand. mike ross.

“I- You don’t even know what I was about to say.”

“Yes, I do.”

he’s cute. pretty blue eyes, a photographic memory, and a boyish charm that you can’t say you’re immune to.

“You were about to ask if he’s had any previous arrests. No, never.”

mike shakes his head. “Sorcery. Speeding tickets?”

you turn to look at him with an exasperated look. “No, officer.” he smiles.

“How did you know? That I’d ask.”

you shrug. “Ancient blood magic.”

a few moments of silence pass, and he’s silently moving his head in tune with his thoughts — like he actually believes you. you decide on mercy.

“It’s the first question lawyers always ask.”

“Ah. Been through this before?”

you shrug.

“Do you always stalk your clients?”

he doesn’t miss a beat. “Only the pretty ones- a hobby of mine.”

you hum, breaking off a piece of your pretzel and handing it to him. he sighs, leaning back.

“Oh you sweet, sweet angel.”

you both continue your walk to pearson/hardman, wanting to get there early to prep for the deposition today. mike breaks the silence once he’s done chewing.

“Do you always feed your lawyers?”

“Only the cute ones,” you break off another piece, handing it to him. “Its a hobby of mine.”

꧁——————————————————꧂

the elevator rings, signifying the end to your journey. mike is in disbelief as you step out of the elevator — mind trying to wrap around your last statement.

“What- are you serious?”

“As a heart attack.”

mike moves to catch up with you. “Okay, multimillion-dollar horse racing company, and you just.. have no security cameras? Zero?”

you turn to face him, giving him a defiant look that makes his heart flutter.

“I don’t see any cameras around here.”

as you approach the glass-doored conference room, mike opens the door for you.

“Touché.”

you shoot him a look across your shoulder before you move to greet your father, already waiting. mike pauses outside, staring, as you hug your father, no doubt offering some sort of reassurance.

“No.”

mikes head snaps toward the voice, harvey’s un-foreseen presence making him jump a little. mike looks around a bit.

“I.. didn’t even-“

harvey points a finger at mike, then at you, then slowly wags it back and forth for dramatics. mike sighs, looking around and putting his hands in his pockets, waiting for his scolding to be done.

“Harvey-“

“Uh uh.”

“Harvey.”

harvey continues his finger wag. “Micheal.”

“Harvey.”

harvey walks backwards towards the door, opening it with his free hand. “Don’t.. do it.”

mike rolls his eyes, following harvey into the room.

okay. don’t get with the funniest, most beautiful woman you’ve ever seen. got it. easy.

easy. right?

the look you give him as he sits down proves him otherwise.

[gynandromorph]

so strangulation is a running theme in idletry. an important one. with shiloh, if the prior content thus far hadn't made it obvious. the thing about naked mole rats is that they can survive without oxygen for up to 20 minutes. they do this by metabolizing fructose like a plant, circumventing the need for oxygen. this can be a problem for a mole rat who wants some kind of choke high. however, manual strangulation frequently incapacitates and kills by applying pressure on the arteries in the neck, which are much more essily compressed than the trachea. even a mole rat will black out (and die) if blood is completely cut off from the brain, at the same speed as any mammal, which is good news for shiloh.

relatedly, one may know from watching enough cave diving videos that a single gulp of air that is mostly carbon dioxide will incapacitate a human instantly due to a phenomenon called acute respiratory acidosis, where the sudden uptake of carbon dioxide beyond what the kidneys and lungs can handle causes the blood to become fatally acidic. this is a separate phenomenon from dying due to a lack of oxygen to power metabolic processes. I wondered if they are also resistant to high CO2 concentrations; it turns out that they aren't just resistant to high CO2 – naked mole rats may literally depend on high concentrations of CO2 produced by huddling together in deep tunnels, as studies have observed that naked mole rats can start to hyperventilate and have seizures as they enter respiratory alkalosis, or, the opposite of acidosis. this is due to a complicated mutation that affects GABAergenic processes due to a cascade of molecular interactions. GABA is an important inhibitory chemical that regulates activity in the brain, and it is why GABA targeted drugs such as benzodiazepines function as immediate rescue medications to stop cluster seizures.

tangentially, shiloh is shown in the comic to take benzos recreationally, so I will have to think about that. it is not an issue, of course, because these seizures in naked mole rats can be stopped with the same medications, and they likely react the same way to the drugs as other mammals, but produce and regulate GABA differently as an adaptation to high CO2 environments. they really are little freaks of nature

[cleverwordsandotherstuffilike]

Lazarus phenomenon

Autoresuscitation is a phenomenon of the heart during which it can resume its spontaneous activity and generate circulation. It was described for the first time by K. Linko in 1982 as a recovery after discontinued cardiopulmonary resuscitation (CPR). J.G. Bray named the recovery from death the Lazarus phenomenon in 1993. It is based on a biblical story of Jesus’ resurrection of Lazarus four days after confirmation of his death. Up to the end of 2022, 76 cases (coming from 27 countries) of spontaneous recovery after death were reported; among them, 10 occurred in children. The youngest patient was 9 months old, and the oldest was 97 years old. The longest resuscitation lasted 90 min, but the shortest was 6 min. Cardiac arrest occurred in and out of the hospital. The majority of the patients suffered from many diseases. In most cases of the Lazarus phenomenon, the observed rhythms at cardiac arrest were non-shockable (Asystole, PEA). Survival time after death ranged from minutes to hours, days, and even months. Six patients with the Lazarus phenomenon reached full recovery without neurological impairment. Some of the causes leading to autoresuscitation presented here are hyperventilation and alkalosis, auto-PEEP, delayed drug action, hypothermia, intoxication, metabolic disorders (hyperkalemia), and unobserved minimal vital signs. To avoid Lazarus Syndrome, it is recommended that the patient be monitored for 10 min after discontinuing CPR. Knowledge about this phenomenon should be disseminated in the medical community in order to improve the reporting of such cases. The probability of autoresuscitation among older people is possible.

National Library of Medicine

[survivingsusac]

What do you know about hyperchloremia?

It’s latin for high chloride in the blood.

Jumping right in today because I'm too tired for my typical rambles. Unusual, I know. And borderline concerning.

I got a complete blood panel workup done this week. It's a typical lab ordered for people who are on intravenous or subcutaneous immunoglobulins. I was on intravenous and now I do my own subcutaneous. A complete blood panel is used to make sure that the somewhat heavy medication isn't taking a negative toll on your body's organs, focusing on the kidney and liver function. As those are the organs that filter things out of the circulatory system.

Pretty much everything was in normal levels which is great. I like being “healthy."

That was ironic humor for those of you who may have missed it. Aurora is not “healthy,” but she finds it ironically funny that her levels are in the ”healthy” range.

Interestingly, there was one metric that was on the tippy top high end of the normal range. My chloride levels.

What is chloride?

Chloride is a mineral electrolyte in your blood which helps maintain the acid base balance in your blood. Chloride is measured on a spectrum called the pH scale, which ranges from zero to 14. 7, being smack dab in the middle, is true neutral. Healthy pH of blood is normally slightly basic with a pH range of about 7.35 to 7.45. Usually, the body maintains the pH of blood close to 7.40. Blood tests, like my full blood panel work up, measure the acid base balance by measuring the pH and levels of carbon dioxide-a gas which makes your blood more acidic-and bicarbonate-a base, present in antacids like Alka seltzer-in the blood.

Electrolytes help control nerve and muscle function.

*This information immediately connected little dots in my brain between spasticity and chloride*

The amount of chloride in your blood is often measured with other electrolytes to monitor kidney disease heart failure liver disease and high blood pressure.

What part of your body makes chloride?

High cortisol levels play a part in chloride increases. Cortisol, often called the stress hormone, is produced by the adrenal glands. The adrenal glands sit like tiny little berets on the top of each kidney.

Higher chloride levels in brain region weakens synaptic transmission in the cortex. High chloride = slow brain neuron firing, like you’re sleeping.

What does a high chloride level really mean? Explain it like I’m five, please.

High chloride can indicate that you are dehydrated, that you have kidney disease, that you have metabolic acidosis or respiratory alkalosis. Metabolic acidosis is when your blood is too acidic (low on the pH scale). Respiratory alkalosis is when you breathe excessively or hyperventilate so you have too much carbon dioxide in your blood so it’s more basic (high on the pH scale).

The most common culprit for elevated chloride is dehydration. And your girl Aurora is chronically dehydrated. So while I have my theories of why my adrenal glands began over-producing cortisol, I also recognize that I have a serious problem with keeping myself hydrated.

Side bar:

If you can’t connect the dots to how I would have experienced an increase in cortisol-the stress hormone-would play a role in a physiological response in my body, all I can say is have you read the blog? Not trying to be rude. But here’s the bullet point Spark Notes style version:

Fight or flight response active for entirety of marriage

Adrenal glands on, increase in cortisol and apparently chloride

Habitual issue with hydration (not helping the chloride processing situation)

That’s it. That’s my Spark Notes version.

Aurora is verbose by nature, but she can break things down into the short and sweet. But you’ll need the contextual knowledge for what is contained in those bullets points for it to mean much to you intrinsically.

So, just…read the blog.

Surviving Susac,

Aurora

[registerednursern]

ABG Interpretation Notes, Mnemonics, and Workbook by Nurse Sarah

ABG Interpretation Notes, Mnemonics, and Workbook by Nurse Sarah! If you are studying arterial blood gas interpretation, you may feel a little overwhelmed about all the material you must know in order to interpret the lab values. For example, you may be completely confused on acid-base imbalances (respiratory acidosis vs, respiratory alkalosis or metabolic acidosis vs, metabolic alkalosis), if…

[princessbubblegumandjustice]

I hate writing about metabolic alkalosis I hate it so freaking much

Intravascular depletion this proximal renal tube that hydrogen and potassium in the urine blah blah

bro I don’t understand it god damn

[twinkl22004]

“Bartter Syndrome Type-3”, Victor McKusick, “Mendelian Inheritance in Man”, 1966.

Here I present: “Bartter Syndrome Type-3”, Victor McKusick, Mendelian Inheritance in Man’, 1966.  INTRODUCTION. Tubulopathy is a disease affecting the renal tubules of the nephron.  Bartter syndrome (BS) is a tubulopathy that causes polyuria, hypokalemia, hypochloremic metabolic alkalosis, and normotensive hyperreninemic hyperaldosteronism. Gitelman syndrome was formerly considered a subset…

[thisisthevoice]

It bothers me when pseudo science believers talk about making your body more alkaline via diet or whatever. It doesn't work. Your body tightly controls your blood's pH. You can eat straight up sodium bicarbonate (in limited amounts) and you'll just pee it out (we did this as an experiment in one of my nursing prerequisites - I peed, tested the pH, then drank a sodium bicarbonate solution and retested my pee after. It was indeed more basic. Kinda cool)

If your blood is too alkaline. That is not good. Your blood likes to be a certain pH for a reason. If its compensatory mechanisms fail there's either a huge issue with your respiratory system (respiratory alkalosis) or some other body process (metabolic alkalosis - from loss of fluid due to vomiting/diarrhea/dehydration, from ingesting too much bicarbonate/alkaline stuff, from a disease process,.etc etc).

Medical pseudoscience bothers me so much 😭

[glassbottledwater]

Is Alkaline Water Healthier Than Regular Water?

Introduction

Water is essential for life, and staying hydrated is crucial for overall health. But not all water is the same. Alkaline water has gained popularity in recent years, with many touting its potential health benefits. But is alkaline water really healthier than regular water? In this article, we delve into the science and claims behind alkaline water, comparing it to regular water to help you make an informed decision.

Understanding Water pH

Water pH is a measure of how acidic or basic water is on a scale of 0 to 14, with 7 being neutral. A pH below 7 indicates acidity, while a pH above 7 indicates alkalinity. Most drinking water has a neutral pH around 7.

What is Alkaline Water?

Alkaline water typically has a pH between 8 and 10. It may also contain alkaline minerals like calcium, magnesium, and potassium, which are believed to offer various health benefits.

Regular Water: Composition and Benefits

Regular water, commonly known as tap or bottled water, usually has a pH close to neutral. It provides essential hydration and is often fortified with minerals.

Alkaline Water vs. Regular Water

Comparing alkaline water to regular water involves examining differences in pH, mineral content, and purported health benefits.

Health Claims of Alkaline Water

Proponents of alkaline water claim it can neutralize acid in the bloodstream, boost metabolism, and improve nutrient absorption. Some believe it can slow aging, increase energy, and aid in disease prevention.

Scientific Evidence on Alkaline Water

The scientific community is divided on the benefits of alkaline water. While some studies suggest potential benefits, others find no significant health advantages over regular water.

Potential Risks of Alkaline Water

High consumption of alkaline water may disrupt the body's natural pH balance, leading to alkalosis—a condition characterized by nausea, vomiting, and muscle twitching.

How to Make Alkaline Water

Alkaline water can be made at home using various methods, including adding baking soda, lemon, or pH drops to regular water.

Natural Sources of Alkaline Water

Certain natural sources, like springs and artesian wells, produce water with naturally high pH levels due to the presence of alkaline minerals.

Commercial Alkaline Water Brands

Many brands market alkaline water, often at a premium price. Popular brands include Bear Springs, Essentia, Evamor, and Icelandic Glacial.

Cost Comparison: Alkaline vs. Regular Water

Alkaline water is generally more expensive than regular water. We explore whether the cost difference is justified by potential health benefits.

Environmental Impact

Bottled alkaline water contributes to plastic waste and environmental pollution. We examine the ecological footprint compared to regular bottled water.

Popular Myths About Alkaline Water

Debunking common misconceptions about alkaline water, such as the idea that it can cure cancer or dramatically alter the body's pH.

Expert Opinions on Alkaline Water

Health professionals and nutritionists weigh in on the benefits and drawbacks of drinking alkaline water.

Alkaline Water and Exercise Performance

Investigating claims that alkaline water can enhance athletic performance and recovery.

Alkaline Water for Digestive Health

Exploring whether alkaline water can aid in digestion and relieve gastrointestinal issues.

Alkaline Water and Bone Health

Discussing the potential impact of alkaline water on bone density and overall skeletal health.

Impact on Blood Pressure

Analyzing the effects of alkaline water consumption on blood pressure regulation.

Skin Health and Alkaline Water

Examining the potential benefits of alkaline water for skin hydration and overall complexion.

Alkaline Water and Kidney Health

Considering how alkaline water may affect kidney function and the management of kidney stones.

Can Alkaline Water Help with Acid Reflux?

Evaluating the claim that alkaline water can provide relief from acid reflux and GERD symptoms.

Alkaline Water and Weight Loss

Assessing whether alkaline water can contribute to weight loss efforts through metabolism and appetite regulation.

Alkaline Water in Cancer Prevention

Investigating the controversial claim that alkaline water can help prevent cancer.

Alkaline Water for Detoxification

Discussing the role of alkaline water in detoxifying the body and promoting overall health.

The Role of Alkaline Water in Hydration

Comparing the hydration efficacy of alkaline water versus regular water.

Flavor and Taste Comparison

Subjective analysis of the taste differences between alkaline and regular water.

Alkaline Water Machines

Overview of devices that can produce alkaline water at home, including their cost and effectiveness.

The Role of Diet in Alkaline Water Benefits

Understanding how an alkaline diet complements alkaline water consumption for overall health.

Frequently Asked Questions

Q. What is the main difference between alkaline water and regular water?

A. Alkaline water has a higher pH level than regular water, often due to added minerals.

Q. Can drinking alkaline water improve my health?

A. Some studies suggest benefits, but the scientific consensus is not definitive.

Q. Are there any risks associated with drinking alkaline water?

A. Excessive intake can lead to alkalosis, causing symptoms like nausea and muscle twitching.

Q. How can I make alkaline water at home?

A. You can add baking soda, lemon, or pH drops to regular water to increase its pH.

Q. Is alkaline water more expensive than regular water?

A. Yes, commercial alkaline water is generally pricier than regular bottled water.

Q. Does alkaline water taste different from regular water?

A. Some people notice a difference in taste, often described as smoother or slightly sweeter.

Conclusion

The debate over whether alkaline water is healthier than regular water is ongoing. While some believe in its benefits, scientific evidence remains inconclusive. It's essential to consider personal health needs, preferences, and potential risks when deciding whether to incorporate alkaline water into your daily routine. Ultimately, staying hydrated is the most important factor, regardless of the type of water you choose.

[alkonicindustries17]

Choosing the Right Alkaline Water Ionizer: Understanding pH Levels and Quality

People these days have become aware of drinking purified water. It is done by making the tap water suitable for drinking by purifying it on your own. But do you know that only purification of the water doesn’t make it safe for drinking? You must have heard the term ‘pH level’, but do you know what it means? Water with a well-balanced pH level is essential. Let’s check out how.

What is the pH level?

PH is a numerical way of measuring the acidity or alkalinity of a fluid, on a scale from 1 to 14. Neutral solutions (such as pure water) have a pH of 7, acidic solutions have a pH lower than 7, and alkaline solutions (also called ‘basic’) have a pH higher than 7. Do you know the ideal pH of the human body is somewhere between 7.35 and 7.45? Therefore, a minor fluctuation in the body’s pH level can severely affect many organs.

Importance of pH in Drinking Water

The pH level affects the chemical properties of water and how it reacts to other substances. PH can impact the color, odor, and taste of water as well. The pH value of drinking water may vary depending on several factors, like its source, climatic conditions, etc.

The pH level in drinking water is important as it affects the chemical properties of the water. For example, high pH levels in drinking water can build mineral deposits. On the other hand, low pH levels can dissolve materials like metals. Very high or low pH of drinking water can also make the water unusable. Therefore, a well-balanced pH level in the water is a must.

General Water pH levels

Tap Water: About 7.5

Distilled RO Water: 5 to 7

Common Bottled Water: 6.5 to 7.5

Bottled Water labeled as Alkaline: 8 to 9

Risks Associated With Unbalanced pH Levels

1. Damage to Teeth

Consuming acidic water can affect your overall dental health. Because water with a low pH increases the risk of decay of the tooth.  

2. Lowers Stomach Acidity

Basic water may lower the pH in the stomach. This could lower the stomach’s natural acid, which is needed to kill bacteria preventing them from passing into the bloodstream.

3. Poor Bone Health

Water with a higher pH level may decrease the body’s free calcium, which can affect bone health.

4. Damage Plumbing System

The corrosive properties of acidic water may also damage your home’s plumbing system. Water with a low pH can dissolve metal pipes, causing heavy metals to leach into your water.

5. Metabolic Alkalosis

Too much basic water can result in a condition called metabolic alkalosis, which imbalances the body’s normal pH. Resulting in vomiting, nausea, muscle twitching, hand tremors, and confusion.

Understanding Alkaline Water Varieties

Choosing the right alkaline water can be a daunting task and Alkaline Water Ionizer. Here is a list of all the forms of alkaline water to choose from.

1. Electrolyte-Enhanced Water: It is filled with electrolytes like potassium and sodium. This variety aims to replenish essential minerals while offering alkalinity.

2. Ionized water: This water type passes through a machine that alters its pH level, making it more alkaline. It is processed through ionization.

3. Enhanced Alkaline Water: This type of water undergoes various filtration processes to elevate its alkalinity artificially.

Get alkaline water at home

After debunking all the myths and misconceptions, trying alkaline water is not harmful. Alkaline water can be produced using special alkaline water ionizers. There are many options available on the market. You can make your ionized alkaline water at home by simply installing an alkaline water ionizer at home. Set up an Alkaline Water Ionizer today with Alkonic. You can also book a free demo from https://alkonic.com

[teslahealthylife]

Alkaline water benefits and risks

Tesla Healthy Life's alkaline water purifier maintains optimum pH levels to maximize hydration and boost metabolism. Alkaline water may provide advantages such as increased hydration and antioxidant activity. However, excessive ingestion might result in alkalosis or electrolyte imbalance. Tesla's purifier provides safe, controlled alkalinity, reducing possible hazards and encouraging healthier living.

[ameerunsblog]

Disturbances In Water Electrolyte And Acid Base Balance Short Essays

[15kbells]

The fact that I’m in medical school, and I still regularly think back to one formative shikamaru/gaara modern-day AU I read like 10 years ago whenever I’m thinking about the effects of metabolic alkalosis and hypokalemia. In the fic, Ino had a seizure after a chronic battle with bulimia nervosa.

[vasanthasworld]

Disturbances In Water Electrolyte And Acid Base Balance Short Essays