#metabolomic

[myblogscmi]

A Single Cell Analysis Can Also Be Used By Pharmaceutical Businesses To Quantify Medication Content.

                                                Single Cell Analysis

The study of a living organism's transcriptomic, genomic, metabolomic, and proteomic components at the single-cell level is known as single-cell analysis. The human genome can be measured, analysed, and sequenced with the use of Single Cell Analysis. Single-cell analysis in clinical diagnostics is anticipated to standardise and automate workflows with significant data for on-going cancer monitoring and eventually novel therapy approaches for patients.Pharmaceutical firms use single-cell analysis for medication development and discovery. The examination will show how the treatment affects DNA and protein levels, assisting in the pre-clinical development of the medication.

The high throughput findings and imaging capabilities of the single cell analysis system aid in the visualisation of individual cells. Pharmaceutical businesses also quantify the medication content using Single Cell Analysis techniques. Understanding different immobilising mechanisms is aided by this. Single cell analysis systems are required for a number of ongoing studies. The single cell analysis technology aids in the detection and analysis of infectious illnesses and food-borne pathogens.A new method called single cell analysis makes it possible to sequence the whole human genome at the level of a single cell. In particular, with its sensitivity increased to single cell level, this covers genomics, transcriptomics, proteomics, epigenomics, and metabolomics.

Discover More@ https://bit.ly/3ysKlAF

[ucsdhealthsciences]

You Are What You Eat, Metabolomically Speaking

The connection between nutrition and health outcomes is surprisingly indirect. For example, we know that fruits and vegetables are good for you. They’re packed with beneficial stuff like vitamins and fiber. However, it’s far less clear what exactly happens inside the body when you eat them — or any other kind of food.

Researchers have historically relied on tools like food frequency questionnaires and diaries to provide clues, but in a new paper, researchers at UC San Diego describe an approach called untargeted metabolomics that identifies the vast number of molecules derived from food and links them to relevant chemical inventories.

“The expanded ability to understand how what we eat translates into products and byproducts of metabolism has direct implications for human health,” said co-corresponding author Pieter Dorrestein, PhD, director of the Collaborative Mass Spectrometry Innovation Center at Skaggs School of Pharmacy and Pharmaceutical Sciences at UC San Diego.

“We can now use this approach to obtain diet information empirically and understand relationships to clinical outcomes. It is now possible to link molecules in diet to health outcomes not one at a time but all at once, which has not been possible before.”

The study has “huge implications” for future research, say the authors.

“The potential to read out diet from a sample directly has huge implications for research in populations, like people with Alzheimer’s Disease, who may not be able to remember or explain what they ate,” said co-corresponding author Rob Knight, PhD, director of the Center for Microbiome Innovation at UC San Diego.

“And in wildlife conservation applications. Good luck getting a cheetah or a gorilla, to name just two species out of the hundreds we’re studying, to fill out a food diary.”

— Scott LaFee

[unopenablebox]

i actually do think i’m better than most people who maintain a biotech oriented science twitter presence

[netbiopub]

Lilac (Syringa oblata) genome provides insights into its evolution and molecular mechanism of petal color change. Ma, et al., Communications biology doi: 10.1038/s42003-022-03646-9.

[mmr-14]

The Metabolomics is the systematic study of chemical processes in cell metabolism that involve metabolites, small molecule substrates, intermediates, and products.

[myalgicencephalomyelitiscfstom]

Press release for this Canadian study [Metabolomic and immune alterations in long COVID patients with Chronic Fatigue Syndrome]:

“We do not actually believe that long COVID is a separate new disease,” explains rheumatologist and clinical immunologist Jan Willem Cohen Tervaert, professor of medicine, who is an expert in fatigue associated with rheumatic illnesses.

“Some symptoms — such as the loss of taste and chest pain — are very specific for COVID, but we see a common pathway with ME/CFS, which leads to the same fatigue, brain fog, post-exertional malaise, widespread pain and non-refreshing sleep,” he says.

[byimarcgroup]

Metabolomics Market 2023: Industry Trends, Size, Growth and Forecast 2028

According to the latest report by IMARC Group, titled, “Metabolomics Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2023-2028” The global metabolomics market size reached US$ 2.4 Billion in 2022. Looking forward, IMARC Group expects the market to reach US$ 4.7 Billion by 2028, exhibiting a growth rate (CAGR) of 11.55% during 2023-2028. Metabolomics is the study and…

[arogyadhamr]

Panchkarma Packages: Rejuvenate Your Mind and Body Naturally

Ayurveda has been a part of the Indian culture for centuries and is known to have numerous health benefits. Panchkarma, an Ayurvedic treatment, is a detoxification process that helps to eliminate toxins from the body and rejuvenate it. Arogyadham Retreat, located in Rishikesh, offers various Panchkarma packages that are tailored to the needs of the individual. In this blog, we will discuss the benefits of Panchkarma and the different packages offered by Arogyadham Retreat.

Benefits of Panchkarma

Panchkarma is a natural detoxification process that helps to eliminate toxins from the body. This process helps to balance the three doshas (Vata, Pitta, and Kapha) and promote overall health and well-being. Panchkarma has numerous benefits, including:

Removes toxins from the body

Improves digestion and metabolism

Enhances mental clarity and focus

Boosts immunity

Reduces stress and anxiety

Relieves joint and muscle pain

Promotes better sleep

Packages Offered by Arogyadham Retreat

Arogyadham Retreat offers various Panchkarma packages that are tailored to the needs of the individual. The packages range from 7 days to 28 days and include:

Panchkarma Detoxification Package: This package includes various detoxification treatments such as Abhyanga, Swedana, Virechana, Basti, and Nasya. This package is suitable for individuals who want to eliminate toxins from their body and improve their overall health.

Panchkarma Rejuvenation Package: This package includes various rejuvenation treatments such as Abhyanga, Swedana, Shirodhara, and Pizhichil. This package is suitable for individuals who want to improve their mental and physical health and reduce stress and anxiety.

Panchkarma Weight Loss Package: This package includes various weight loss treatments such as Udwarthanam, Abhyanga, and Virechana. This package is suitable for individuals who want to lose weight and improve their overall health.

Panchkarma Beauty Package: This package includes various beauty treatments such as Abhyanga, Swedana, and Mukhalepam. This package is suitable for individuals who want to enhance their natural beauty and improve their skin's health.

Panchkarma is a natural detoxification process that has numerous health benefits. Arogyadham Retreat offers various Panchkarma packages that are tailored to the needs of the individual. These packages help to eliminate toxins from the body, improve mental and physical health, and promote overall well-being. So, if you want to experience the benefits of Panchkarma, book a package with Arogyadham Retreat today.

[metwarebio]

Applications

Metabolomics Offers Solutions For You

Metabolomics is widely applicable across different industries from agriculture to medicine. Understanding the chemical profile from various samples will help resolve what is currently happening and what is being observed. Metware Biotechnology has built its processes to handle different types of samples that can help industries with their metabolomics experiments.

 Agriculture & Breeding

Yield and nutrition is important in agriculture, thus understand nutritional value and agronomic traits directly through metabolomics is a critical component in agricultural breeding.

 Microbiome

Gut microbiome is considered a host's second genome and the metabolism of gut microbiota is important for the host's defense against pathogens, nutrient breakdown and uptake, and neuronal signaling. Study the metabolic interactions between host and microbiome through metabolomics.

 Cancer

Metabolism is an essential component to understand the complexity of cancer and human diseases. Many metabolites from body fluids can be use for diagnosis and instruct proper medication or therapy. Metabolomics is the best technology providing these insights.

 Infectious Diseases

Infectious diseases can happen quickly. The 2019 global pandemic of COVID-19 showed that multi-omics examination and rapid pharmaceutical development are needed to combat infectious diseases.

 Metabolic Disorders

Human diseases, from chronic pain to acute infectious diseases, often have metabolic readouts that indicate the state of the disease. Metabolomics has been applied to metabolic disorders such as diabetes and obesity to infectious diseases such as tuberculosis and COVID-19.

 https://www.metwarebio.com/widely-applicable-metabolomics-service/

[redpandaempire]

Liquid N

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[cytoscape-publications]

Profiling the role of microorganisms in quality improvement of the aged flue-cured tobacco. Wu, et al., BMC microbiology doi: 10.1186/s12866-022-02597-9.

[netbiopub]

Profiling the role of microorganisms in quality improvement of the aged flue-cured tobacco. Wu, et al., BMC microbiology doi: 10.1186/s12866-022-02597-9.