#IT expertise

[poorly-drawn-mdzs]

Expertise can't help you here.

[firstoccupier]

Setting Up an IRC Server for Secure Communication in a Future Insurrection

By WPS News Technical ReporterBaybay City | January 20, 2025 In an era marked by digital surveillance and control exerted by technology moguls, the need for independent communication platforms has never been more vital. As social movements and grassroots organizations rise to challenge existing power structures, the requirement for secure channels of communication is paramount. One viable…

[allyourtechpeople]

Comprehensive IT support services, including proactive monitoring, cyber security, and tailored consultation to drive business success.

[akitconsultingservices]

Revolutionize Your Operations with IT Consulting

Engaging a reputable business consultancy in Ashburn, Virginia, can significantly transform your operations, enhancing efficiency and productivity. IT consulting services offer strategic guidance tailored to your business needs, ensuring you leverage the latest technologies effectively.

[mynnthia]

was talking with a friend about how some of dunmeshi fаndom misunderstands kabru's initial feelings towards laios.

to sum up kabru's situation via a self-contained modernized metaphor:

kabru is like a guy who lost his entire family in a highly traumatic car accident. years later he joins a discord server and takes note of laios, another server member who seems interesting, so they start chatting. then laios reveals his special interest and favorite movie of all time is David Cronenberg's Crash (1996), and invites kabru to go watch a demolition derby with him

[im-ignoring-canon]

This isn't even a hot take, but Percabeth weren't smart x dumb. They weren't even book smart x street smart. They were strategic x strategic. Their minds worked in very similar ways that complimented eachother. It's why they were such great friends, it's why they were a formidable team, hell, it's why they could fight a war against a deity with an army of forty fricking kids and win. They shared their braincells, in the most beautiful sense of the phrase and THAT'S why, for me, they're perfect together.

[runninguplenorahills]

Shut up

[reasonsforhope]

A new treatment combining ReCET and semaglutide could eliminate the need for insulin in type 2 diabetes, with 86% of participants in a study no longer requiring insulin therapy. The treatment was safe and well-tolerated, and further trials are planned to confirm these results.

Groundbreaking research presented at UEG Week 2024 introduces a promising new treatment approach for type 2 diabetes (T2D) that has the potential to greatly reduce or even eliminate the need for insulin therapy.

This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of patients.

Globally, T2D affects 422 million people... While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects... and further complicate diabetes management. [Note: Also very importantly it's fucking bankrupting people who need it!!] A need therefore exists for alternative treatment strategies.

Study Design and Outcomes

The first-in-human study included 14 participants aged 28 to 75 years, with body mass indices ranging from 24 to 40 kg/m². Each participant underwent the ReCET procedure under deep sedation, a treatment intended to improve the body’s sensitivity to its own insulin. Following the procedure, participants adhered to a two-week isocaloric liquid diet, after which semaglutide was gradually titrated up to 1mg/week.

Remarkably, at the 6- and 12-month follow-up, 86% of participants (12 out of 14) no longer required insulin therapy, and this success continued through the 24-month follow-up. In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%.

Tolerability and Safety

The maximum dose of semaglutide was well-tolerated by 93% of participants, one individual could not increase to the maximum dose due to nausea. All patients successfully completed the ReCET procedure, and no serious adverse effects were reported.

Dr Celine Busch, lead author of the study, commented, “These findings are very encouraging, suggesting that ReCET is a safe and feasible procedure that, when combined with semaglutide, can effectively eliminate the need for insulin therapy.”

“Unlike drug therapy, which requires daily medication adherence, ReCET is compliance-free [meaning: you don't have to take it every day], addressing the critical issue of ongoing patient adherence in the management of T2D. In addition, the treatment is disease-modifying: it improves the patient’s sensitivity to their own (endogenous) insulin, tackling the root cause of the disease, as opposed to currently available drug therapies, that are at best disease-controlling.”

Looking ahead, the researchers plan to conduct larger randomized controlled trials to further validate these findings. Dr. Busch added, “We are currently conducting the EMINENT-2 trial with the same inclusion and exclusion criteria and administration of semaglutide, but with either a sham procedure or ReCET. This study will also include mechanistic assessments to evaluate the underlying mechanism of ReCET.”

-via SciTechDaily, October 17, 2024

--

Note: If it works even half as well as suggested, this could free so many people from the burden of the ongoing ridiculous cost of insulin. Pharma companies that make insulin can go choke (hopefully).

[w1f1n1ghtm4r3]

i need mpop to be real so much

[apacnewsnetwork0]

Managed Cloud Services: Panacea for Enterprises

In today’s ever-evolving and fast-paced business landscape, organizations that do not keep up with technological advancements and seek innovative solutions will be left behind. Organizations across industry verticals in this digital era are relying more and more on new-age technologies, specifically cloud computing infrastructure to stay ahead of the curve.  Having existed for many decades now, cloud computing infrastructure continues to offer numerous business benefits to organizations of all sizes. 

Elasticity, scalability, pay-per-use model, streamlining of operations, and other advantages it brings lead to significant improvement in the organization’s bottom line.   

While cloud technology delivers several business advantages, managing and optimizing these services can be challenging and time-consuming as well.  Businesses have to depend on IT expertise and 24/7 support to efficiently leverage cloud services, but not all of them have the resources to house an internal IT team that can keep pace with the constantly evolving technology landscape. This is where managed service providers or MSPs can play a crucial role in supporting organizations to effectively and efficiently navigate the cloud landscape.  

Read More - https://apacnewsnetwork.com/2023/12/managed-cloud-services-panacea-for-enterprises/

[firstoccupier]

Setting Up an IRC Server for Secure Communication in a Future Insurrection

By WPS News Technical ReporterBaybay City | January 20, 2025 In an era marked by digital surveillance and control exerted by technology moguls, the need for independent communication platforms has never been more vital. As social movements and grassroots organizations rise to challenge existing power structures, the requirement for secure channels of communication is paramount. One viable…

[spidertroupeart]

Good morning sonadow nation

[madlori]

We've all seen this cartoon a thousand times and I'm always struck by how relevant and accurate it is.

Lemme share my own Quartz moment.

My degrees are in organic chemistry. When I was doing my undergraduate research project, my mom asked me what it was about. My mother is a smart woman but has zero science education.

I thought, okay, start simple. So I drew this:

I opened my mouth to start talking about the project and she stopped me and said:

"What do those lines mean?"

I just sat there mute, utterly wrong-footed. This is a totally reasonable question, but to me, it was like I'd written a word and she'd asked me what the letters meant. This notation (standard molecular drawing notation) is so second nature to me that it's every bit as natural as writing English.

I had not fully appreciated how far I'd need to downshift to explain this. A friend of mine on the same project was asked to give a talk to a group of non-science folks about what we were doing and she made slides with overlays to let them know what the notation means.

The above notation is shorthand for this:

The lines are bonds. The single line is a single bond, the double line is a double bond (well...in benzene technically each bond is 1.5 bonds but this is the usual way it's drawn even though it's not really accurate). Each corner is a carbon atom. We don't draw the carbon atoms unless we're calling attention to them, and we leave off the hydrogens entirely unless they're significant for some reason, they're just understood to be there.

None of this would be obvious to someone who's never taken chemistry. But I had to remind myself of this, and my mom's question knocked me for a loop for a second.

We got it sorted out.

This really becomes an issue when there are news events having to do with science. Vaccines come to mind. People have HEARD of DNA, but they've barely heard of RNA, and even if they have, most don't understand it, or what it does or what it means. There was a lot of effort put into making analogies and cartoons and other tools to help explain how an mRNA vaccine works, but too many people still hear it and think SCARY.

And don't get me started on those "if you can't pronounce the ingredients, don't eat it" idiots with their naturalistic fallacies and woo-woo pseudoscientific snake oil bullshit YES I TAKE IT PERSONALLY.

[theabigailthorn]

"Good" Acting

i have a theory that a lot of people say acting is "good" when they're emotionally moved by it, and a lot of cishet white people have a lifelong habit of not listening or empathising when minoritised people speak, so minority actors get called "bad" even when they display some pretty fucking amazing technical skill

[lolababyelf]

Violet: *Glares*

Bodhi *flinches*: Xaden’s been rubbing off on you Sorrengail

Ridoc: *snorts* I bet he has