every-tome · 1 year ago
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onlineviolence · 2 years ago
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what’s ur favourite SCP
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alana-celeste-luna · 11 days ago
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Redactober Day 17: SCP-7999, Meet Me in the Stars
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Class: Integrated
Description: "Come find us. We'll be waiting."
OriTiefling, from the SCP Wiki. Source: https://scpwiki.com/scp-7999.
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oritiefling · 3 months ago
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Hey so uh SCP-7999 is currently 6 votes away from +1000. If you haven't had time to check it out please do!!!!
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corpsentry · 5 months ago
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ass in the air on my hands and knees searching for link/allen (romantic platonic idgaf in this economy) fanwork i scoured the ao3 tag dry and 8 years of tumblr posts and now i am Two fists deep in pixiv, dodging projectiles of pathetic ai porn, desperately looking for crumbs. i’ve done it again folks i found a more or less dead fandom and got stuck on the niche pairing of the main character and the guy who debuted with a bowl cut and now there is nothing to be done but CRY LOUDLY and then (some time later) EQUIP PEN
#(through tears) BE THE CHANGE YOU WANT TO SEE IN THE WORLD#fuckass niche as fuck pairings always nerf me for some reason i’ve got a thing for the…. the Unexpected. or the Unperceivdd#i just think there’s something so compelling about allen’s idealism in spite of the horrors he’s experienced contrasted with#link’s single mindedness in his devotion to reveiller or whomstever the fuck (can’t spell europe)#being as he is an orphan who has never had anyone else in his life#but then allen comes along and suddenly he’s forced to be in close quarters with another human being for a long ass time#and allen obviously hates it at first but they’re both Food Enjoyers and allen’s so. he’s so idealistic. he thinks he can save everyone#meanwhile link has never cared about anyone except his friends who all became third exorcists and cocked off + leveiller + now. now now#howard ‘i’m at war with myself’ link#HOWARD LINK HAS ONLY EVER AFFORDED HIMSELF TWO MERCIES#THE FIRST IS HIS FEELINGS OF LOYALTY TOWARDS REVEILLE#WHICH AT SOME POINT IN HIS EMPLOYMENT TRANSCENDED A MERE SENSE OF OBLIGATION#THE SECOND IS ALLEN WALKER#meanwhile allen’s never had anyone see him at his lowest so often on the pure basis of fuckass watch a dog a (mario voice) duty#the forced vulnerability into a genuine sense of concern but the lines are eternally blurred#throw in link’s transparency when kanda drags him out of dog zone and he’s like okay ya this is what i’m here to do#and allen’s unequivocal acceptance of him all the same#AND THE WAY HE BLUSHES WHEN ALLEN PINCHES HIS NOSE (7999 psychic damage sustained. critical hit!)#i like unlikely and difficult connections which require infinite energy and faith to sustain#i like what they’ve got going there#it compels the Fuck out of me#ok now that i’ve yapped this much i Must. i Must write. so write i will (later)#after (?) this comic and also my mom and i finish watching blossoms in adversity which . favorite chinese period drama ever fyi#ok good night i sleep#olio#gelmo
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thedemonscrawler · 1 year ago
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e1igius · 2 years ago
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come into thg hell with me ; just a warning , it's darker than the books.
you don't even have to write , give me a year and your kid gets to be a victor
10: lady gray baird , tweleve
11: mags flanagan , four
22: woof , eight
31: seeder , eleven
38: porter millicent tripp , five
40:
41:
42: [ district 9 female ] , nine
43: beetee latier , three
44: lyme , two
45: chaff , eleven
46: [ district 9 male ] , nine
47: brutus , two
48: [ district 5 male ] , five
49:
50: haymitch abernathy , tweleve
51:
52: courtland gentry , two (@sierra6x)
53: blight , seven
54: [ district 5 female ] , five
55: [ female morphling ] , six
56: [ male morphling ] , six
57:
58:
59: cecelia , eight
60: huckleberry sawyer , three *
61:
62: enobaria , two
63: gloss , one
64: cashmere , one
65: finnick odair , four
66:
67: agustus braun , one
68: [ district 10 male ] , ten
69:
70: annie cresta , four
71: johanna mason , seven
72: prynne gatsby , three ** critical to hucks storyline
73: [ district 2 male ] , two
74: katniss everdeen & peeta mellark , tweleve
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brightcarnate-a · 2 years ago
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“Hey. Don’t cry.
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8000 different anomalies, okay?”
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saintmeghanmarkle · 1 year ago
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She's gloating about her podcast here. The comments are hilarious. Everyone can see through her insincerity. https://youtu.be/1hhsvnV5CIc by u/Tricky-Apricot-7999
She's gloating about her podcast here. The comments are hilarious. Everyone can see through her insincerity. https://youtu.be/1hhsvnV5CIc No text found post link: https://ift.tt/5duP9ao author: Tricky-Apricot-7999 submitted: June 18, 2023 at 06:56PM via SaintMeghanMarkle on Reddit
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864carsbrisbane · 2 years ago
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(via OUR CARS - 864 Wholesale Cars)
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querical-equinox · 2 years ago
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for the ask game! 🍂 What's your fav season?
Oooo Autumn, hands down! Everything is finally starting to cool off, and the worst of the biting bugs in my area are tucking away for winter. I absolutely adore watching the color shift here, and the bird migration begin ^^ also it holds halloween, my fave holiday lol
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covid-safer-hotties · 1 month ago
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Also preserved on our archive
By Pandora Dewan
The virus that causes COVID-19 might be becoming resistant to antiviral treatments, new research has warned. But should we be concerned?
The antiviral drugs nirmatrelvir and remdesivir are recommended for use against mild to moderate SARS-CoV-2 infections to reduce the risk of progression to more severe symptoms and hospitalization in high-risk individuals. However, long-term exposure to these treatments can push the virus to evolve new mutations that allow it to evade these medications.
Antiviral resistance is a particular concern in immunocompromised patients, who take longer to clear the infection and therefore require antiviral treatment over a longer period of time. As a result, viruses in immunocompromised, or other high risk patients, have more time to evolve these drug-resistant mutations.
This week, two studies were published on the evolution of drug-resistant strains of SARS-CoV-2, with both research groups finding drug resistant mutations in immunosuppressed patients being treated with either nirmatrelvir or remdesivir. The first group also found that these resistant mutants may also be able to spread between patients, posing a major challenge to disease management and control in the future.
This study, conducted by researchers at Cornell University and the National Institutes of Health (NIH) and published in the journal Nature Communications on September 18, investigated the impact of antiviral treatment on the emergence of resistant SARS-CoV-2 mutations in 15 immunocompromised patients. All patients received remdesivir while three also received nirmatrelvir and four also received monoclonal antibodies.
By sequencing the virus's DNA, the researches found that the majority of patients carried viruses with some sort of protective mutation against these antivirals. By studying these viruses in the lab, the team were able to confirm their reduced sensitivity to both remdesivir and nirmatrelvir treatment. They also demonstrated that these resistant mutants were able to be effectively transmitted between individuals, at least in hamsters. However, this resistance was overcome by combined antiviral treatment.
In the second study, conducted by researchers from Harvard University, Brigham and Women's Hospital, the University of Pittsburgh and Stanford University and published in the journal JAMA Network Open, scientists assessed a cohort of 165 patients with COVID-19 infections between 2021 and 2023. Participants were divided into those who received antiviral treatment and those who did not.
The team found that antiviral-resistant mutations were more likely to appear in patients who had received antivirals compared to those who did not. This was particularly pronounced among those who were immunocompromised and those who received nirmatrelvir compared to remdesivir.
However, most of these mutations were detected at low levels and reverted back to their original form.
"In this cohort study of 156 participants, treatment-emergent nirmatrelvir resistance mutations were commonly detected, especially in individuals who were immunosuppressed," the researchers wrote. "However, these mutations were generally present at low frequencies and were transient in nature."
Thus, they concluded that, at present, these resistant variants were unlikely to spread through the general population. However, they added that we should continue to monitor these mutations and drug usage patterns.
References Nooruzzaman, M., Johnson, K.E.E., Rani, R. et al. Emergence of transmissible SARS-CoV-2 variants with decreased sensitivity to antivirals in immunocompromised patients with persistent infections. Nat Commun 15, 7999 (2024). doi.org/10.1038/s41467-024-51924-3 www.nature.com/articles/s41467-024-51924-3
Tamura TJ, Choudhary MC, Deo R, et al. Emerging SARS-CoV-2 Resistance After Antiviral Treatment. JAMA Netw Open. 2024;7(9):e2435431. doi:10.1001/jamanetworkopen.2024.35431 jamanetwork.com/journals/jamanetworkopen/fullarticle/2824050
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oritiefling · 2 years ago
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Agent Basil Sias, the Foundation’s ambassador to the stars.
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sexylonestar · 3 months ago
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Nylon # 7999
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apatheticlexicographer · 7 months ago
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POLL FOR BOOPS GIVEN
values taken from this post. there weren't enough poll slots for everything so i tried to group them evenly, bearing in mind that ppl are more likely to have reached the lower scores
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e1igius · 2 years ago
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things to do
- blog graphics - intro post - stylize bio - verse mini bios (t100, tlou, thg, st & wednesday for now)
mini verse info:
the hundred - old canon , huck is a prisoner w/ eligius iv  the hunger games - victor , 60th hunger games the last of us - defects from military post outbreak stranger things - ( young!huck ) enlisted marine , on leave to hawkins wednesday - huck’s a professor @ the school
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