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#Good Bacteria
bpod-bpod · 2 years
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Bacterial Identity Cards
These are electron microscope pictures of near-identical looking bacterial flagella – the tiny tail-like structures that propel the microorganisms through fluids. According to recent research, all flagella are not the same, however, and the small differences that exist are critical to how the human immune system determines which bacteria are friendly and which are not. The principal component of flagella is flagellin, and recognition of this protein by gut immune cells can trigger an immune response. Since both friendly and pathogenic bacteria can have flagellin, scientists wondered how the immune cells tell them apart. Screening the flagellins of a variety of gut bacteria has revealed that while some bind and activate the immune cells, others bind and do not, and some don’t bind at all. Subtle differences in the amino acid sequence of the protein, it turns out, are enough to give some bacteria a free pass and others the boot.
Written by Ruth Williams
Image by Michael Bell, Ley Lab, Max Planck Institute
Research by Sarah Clasen et al, Ley Lab, Department of Microbiome Science, Max Planck Institute for Biology, Tübingen, Germany
Image copyright held by the original authors
Research published in Science Immunology, January 2023
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lgihospital · 12 days
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supremonutrition · 4 months
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How do Probiotics Support a Healthy Gut Ecosystem?
Imagine trillions of microscopic roommates living within your gut, helping you digest food, fight off illness, and even influencing your mood. These aren't unwelcome invaders, but beneficial bacteria known as probiotics.
Probiotics are live microorganisms that contribute to a healthy gut microbiome, the vast community of bacteria residing in your digestive system. A balanced microbiome is crucial for overall health, and probiotics can help maintain this equilibrium.
What are Probiotics?
Probiotics play a crucial role in maintaining a healthy gut ecosystem by promoting a balanced and diverse community of microorganisms within the digestive tract. These beneficial bacteria, such as Lactobacillus and Bifidobacterium strains, help to crowd out harmful pathogens, thus reducing the risk of infections and supporting overall immune function. Additionally, probiotics aid in the digestion and absorption of nutrients, ensuring that essential vitamins and minerals are effectively processed by the body. They also contribute to the production of short-chain fatty acids, which serve as a vital energy source for the cells lining the intestinal walls. Furthermore, probiotics assist in regulating gut motility, helping to alleviate symptoms of gastrointestinal disorders like irritable bowel syndrome (IBS) and constipation. By maintaining a harmonious balance of bacteria in the gut, probiotics contribute to optimal digestive health, bolstering the body's resilience against various ailments and promoting overall well-being.  Read the blog for understanding the true essence of probiotics in the journey of our gut health.
Digestive Defenders:
One of the most well-researched benefits of probiotics is their role in digestive health. Probiotics can help ease symptoms of irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) [1]. They may also prevent and reduce the severity of antibiotic-associated diarrhoea, a common side effect of these medications [2]. This is because antibiotics kill not only harmful bacteria but also some beneficial ones. Probiotics help replenish the good bacteria and restore balance.
Beyond the Gut:
The influence of probiotics extends beyond the digestive system. Research suggests they may play a role in boosting the immune system, potentially reducing the risk and severity of upper respiratory infections [3]. Some studies also indicate a link between probiotics and mental health, with potential benefits for anxiety and depression [4].
Probiotic Powerhouse:
While naturally present in fermented foods like yoghourt, kimchi, and kefir, incorporating probiotics through supplements can be a convenient way to boost your intake. When choosing a probiotic supplement, look for one that contains multiple strains of bacteria, as diversity is key for a healthy gut microbiome.
Supremo Nutrition for your Gut- A Health Conscious Alternative
Supremo's Ultimate Immunity Support offers a two-pronged approach to keeping you healthy. First, it provides ingredients that fortify your immune system, helping your body fight off illness more effectively. These ingredients might include vitamins, minerals, and antioxidants that support the production and function of immune cells.
Secondly, Supremo's formula promotes optimal gut health. A healthy gut microbiome is teeming with good bacteria that play a crucial role in immune function. By supporting a healthy balance of gut bacteria, Supremo's Ultimate Immunity Support may help your body better defend itself against potential threats.
And to top it all off, this formula is free of added sugar, so you can feel confident you're getting a clean and effective nutritional boost for your immune system.
Listen to Your Gut:
Probiotics are generally safe for most healthy adults. However, it's advisable to consult a doctor before starting any new supplement, especially if you have underlying health conditions or a weakened immune system.
By nurturing the good bacteria in your gut with probiotics, you can take an active step towards promoting better digestion, a stronger immune system, and potentially even improved mental well-being.
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nutritionproducts · 6 months
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What Are Human Milk Oligosaccharides (HMOs)
Human Milk Oligosaccharides (HMOs) are complex sugars found in breast milk, known for supporting a baby's immune system and gut health.
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discoverybody · 6 months
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Probiotics That Are Good For Daily Consumption
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Probiotics, also known as "good bacteria," are live bacteria and yeasts that are useful to the digestive system. They can be found naturally in foods such as yogurt, sauerkraut, and kimchi, as well as in supplements. Probiotics aid to relieve digestive disorders including bloating, gas, and constipation by restoring the balance of microorganisms in our stomachs.
Given the hectic and stressful nature of our lifestyles, incorporating probiotics into our everyday lives is quite useful. Probiotics promote digestion and nutrition absorption, which leads to better digestion, less bloating, and more energy. They also help to support a healthy immune system by strengthening the intestinal barrier and preventing dangerous germs from causing sickness.
Probiotics provide health benefits that extend beyond digestion and immunological function. They have been demonstrated to promote mental health by altering the gut-brain axis, which leads to better mood and less anxiety. Certain probiotic strains, such as Lactobacillus gasseri, can help you lose weight by regulating your appetite and encouraging fat breakdown.
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Good Bacteria: Your Guide to a Healthy Microbiome
Discover the fascinating world of good bacteria and their vital role in maintaining our well-being. This informative article delves into the significance of good bacteria for our gut, skin, mouth, and overall health. Learn how to naturally increase the levels of these beneficial microorganisms and how they help fight against harmful pathogens. Uncover the impact of antibiotics and other factors on good bacteria, and explore ways to replenish them after treatment. From probiotics to fermented foods, find out what nourishes these friendly organisms and the essential functions they perform in our bodies. Embrace the power of good bacteria and optimize your health today!
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reasonsforhope · 2 months
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"When bloodstream infections set in, fast treatment is crucial — but it can take several days to identify the bacteria responsible. A new, rapid-diagnosis sepsis test could cut down on the wait, reducing testing time from as much as a few days to about 13 hours by cutting out a lengthy blood culturing step, researchers report July 24 [2024] in Nature.
“They are pushing the limits of rapid diagnostics for bloodstream infections,” says Pak Kin Wong, a biomedical engineer at Penn State who was not involved in the research. “They are driving toward a direction that will dramatically improve the clinical management of bloodstream infections and sepsis.”
Sepsis — an immune system overreaction to an infection — is a life-threatening condition that strikes nearly 2 million people per year in the United States, killing more than 250,000 (SN: 5/18/08). The condition can also progress to septic shock, a steep drop in blood pressure that damages the kidneys, lungs, liver and other organs. It can be caused by a broad range of different bacteria, making species identification key for personalized treatment of each patient.
In conventional sepsis testing, the blood collected from the patient must first go through a daylong blood culturing step to grow more bacteria for detection. The sample then goes through a second culture for purification before undergoing testing to find the best treatment. During the two to three days required for testing, patients are placed on broad-spectrum antibiotics — a blunt tool designed to stave off a mystery infection that’s better treated by targeted antibiotics after figuring out the specific bacteria causing the infection.
Nanoengineer Tae Hyun Kim and colleagues found a way around the initial 24-hour blood culture.
The workaround starts by injecting a blood sample with nanoparticles decorated with a peptide designed to bind to a wide range of blood-borne pathogens. Magnets then pull out the nanoparticles, and the bound pathogens come with them. Those bacteria are sent directly to the pure culture. Thanks to this binding and sorting process, the bacteria can grow faster without extraneous components in the sample, like blood cells and the previously given broad-spectrum antibiotics, says Kim, of Seoul National University in South Korea.
Cutting out the initial blood culturing step also relies on a new imaging algorithm, Kim says. To test bacteria’s susceptibility to antibiotics, both are placed in the same environment, and scientists observe if and how the antibiotics stunt the bacteria’s growth or kill them. The team’s image detection algorithm can detect subtler changes than the human eye can. So it can identify the species and antibiotic susceptibility with far fewer bacteria cells than the conventional method, thereby reducing the need for long culture times to produce larger colonies.
Though the new method shows promise, Wong says, any new test carries a risk of false negatives, missing bacteria that are actually present in the bloodstream. That in turn can lead to not treating an active infection, and “undertreatment of bloodstream infection can be fatal,” he says. “While the classical blood culture technique is extremely slow, it is very effective in avoiding false negatives.”
Following their laboratory-based experiments, Kim and colleagues tested their new method clinically, running it in parallel with conventional sepsis testing on 190 hospital patients with suspected infections. The testing obtained a 100 percent match on correct bacterial species identification, the team reports. Though more clinical tests are needed, these accuracy results are encouraging so far, Kim says.
The team is continuing to refine their design in hopes of developing a fully automated sepsis blood test that can quickly produce results, even when hospital laboratories are closed overnight. “We really wanted to commercialize this and really make it happen so that we could make impacts to the patients,” Kim says."
-via Science News, July 24, 2024
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sadanduncertain · 1 year
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If what we are reading on Astarion's grave is correct, and he was only 39 years old when he died, that adds an entire new level of tragedy to his character. Not only was he extremely young and emotionally immature by elven standards, but he had barely even lived before he died. It's no wonder that he doesn't remember anything about his past when we ask him about it — 39 years is a small drop of water in comparison to 200 years of abuse. There is simply nothing to remember.
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greatoralhealth · 2 years
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How to Get Good Bacteria In Your Mouth
The mouth is home to millions of bacteria. These bacteria are constantly interconnected and level with each other. This delicate balance can lead to many common problems in oral health. Bad bacteria can cause severe problems in your oral health. Although good bacteria can help offset the effects of this situation,
Read More: Good Bacteria in your Mouth
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wachinyeya · 6 months
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rushinintolove · 8 months
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canisalbus · 1 year
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Odd question, but since they're both dogs and I imagine smell is important to them, what do Machete and Vasco smell like?
Smells are indeed important to them. I think their sense of smell is definitely more keen than ours but not nearly as extreme as that of real dogs. It would be kind of world/society/behavior breaking if one of their senses was that much above what we as humans can even imagine.
Fur absorbs smells more efficiently than skin, so the environment each person spends most of their time in affects the way they smell (the same way your clothes tend to hold scents from the places you've recently been to).
Machete tends to smell mainly of frankincense, the primary ingredient of the sacred incense burned during worship. Smells are hard to describe but to me frankincense smells sweet, smoky, earthy, citrusy, piney, resinous and woody. Evokes the feeling of sanctity. There's also traces of ink, paper and old books. If he had been treated recently and you got really close and knew to look for it, you might be able to detect the cuts where he was bled.
Vasco uses perfumes skillfully, his favorites contain iris root and damask rose. The mellow scent of his high quality soaps often lingers for quite a while as well. If he's been outdoors, there's a more noticeable hint of leather, as well as moisture, earth, greenery, animals and various other nature smells. Since he's characterized by his vitality, I can't escape the feeling that if you were to put your nose on him, he'd smell like a warm, healthy, living thing even more strongly than people usually do, even if you didn't consciously realize it.
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lgihospital · 12 days
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lazylittledragon · 1 year
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y'know i always wondered why it always felt like i was sick for SO long whenever i caught something when i was younger?? then i realised i was waking up at 6am and going to school and doing homework every day so no wonder i spent 2 weeks fighting off colds. the last time i got sick as an adult, i slept in and sat in bed and did nothing as often as i could and i was almost over it in 3 days.
so anyway fuck attendance rewards and shaming kids for taking days off school. let them rest.
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nutritionproducts · 6 months
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Human Milk Oligosaccharides (HMOs) are complex sugars found in breast milk that play a vital role in shaping the infant's gut microbiota, supporting immune development, and protecting against infections. They are not digested by the infant but serve as food for beneficial bacteria in the gut, promoting a healthy microbiome.
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pianokantzart · 3 months
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This is a Mario blog I WILL NOT get into internet fights about hygiene disinformation
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