#Jolie Levine

[boricuacherry-blog]

*Taran Noah Smith

[le-jolie]

Angelina Jolie, Vivienne Jolie-Pitt and Justin Levine photographed by Emilio Madrid for Broadway.com, April 2024

[perezhilton]

Angelina Jolie has a new man. I need to verify if he's straight! But, hey, I'd go straight for Angelina! This and much more on our latest show! CLICK HERE to listen to the newest episode of The Perez Hilton Podcast with Chris Booker in full at PerezPodcast.com 

[nuadox]

Horseshoe crab blood is vital for testing intravenous drugs, but new synthetic alternatives could mean pharma won’t bleed this unique species dry

- By Kristoffer Whitney , Jolie Crunelle , Rochester Institute of Technology , The Conversation -

If you have ever gotten a vaccine or received an intravenous drug and did not come down with a potentially life-threatening fever, you can thank a horseshoe crab (Limulus polyphemus).

How can animals that are often called living fossils, because they have barely changed over millions of years, be so important in modern medicine? Horseshoe crab blood is used to produce a substance called limulus amebocyte lysate, or LAL, which scientists use to test for toxic substances called endotoxins in intravenous drugs.

These toxins, produced by bacteria, are ubiquitous in the environment and can’t be removed simply through sterilization. They can cause a reaction historically referred to as “injection fever.” A strong concentration can lead to shock and even death.

Identifying LAL as a highly sensitive detector of endotoxins was a 20th-century medical safety breakthrough. Now, however, critics are raising questions about environmental impacts and the process for reviewing and approving synthetic alternatives to horseshoe crab blood.

We study science, technology and public policy, and recently published a white paper examining social, political and economic issues associated with using horseshoe crabs to produce LAL. We see this issue as a test case for complicated problems that cut across multiple agencies and require attention to both nature and human health.

Protecting horseshoe crabs will require persuading the heavily regulated pharmaceutical industry to embrace change.

An ocean solution

Doctors began injecting patients with various solutions in the mid-1800s, but it was not until the 1920s that biochemist Florence Seibert discovered that febrile reactions were due to contaminated water in these solutions. She created a method for detecting and removing the substances that caused this reaction, and it became the medical standard in the 1940s.

Known as the rabbit pyrogen test, it required scientists to inject intravenous drugs into rabbits, then monitor the animals. A feverish rabbit meant that a batch of drugs was contaminated.

The LAL method was discovered by accident. Working with horseshoe crabs at the Marine Biological Laboratory at Woods Hole, Massachusetts, in the 1950s and ’60s, pathobiologist Frederik Bang and medical researcher Jack Levin noticed that the animals’ blue blood coagulated in a curious manner. Through a series of experiments, they isolated endotoxin as the coagulant and devised a method for extracting LAL from the blood. This compound would gel or clot nearly instantaneously in the presence of fever-inducing toxins.

Academic researchers, biomedical companies and the U.S. Food and Drug Administration refined LAL production and measured it against the rabbit test. By the 1990s, LAL was the FDA-approved method for testing medicines for endotoxin, largely replacing rabbits.

Producing LAL requires harvesting horseshoe crabs from oceans and beaches, draining up to 30% of their blood in a laboratory and returning the live crabs to the ocean. There’s dispute about how many crabs die in the process – estimates range from a few percent to 30% or more – and about possible harmful effects on survivors.

Today there are five FDA-licensed LAL producers along the U.S. East Coast. The amount of LAL they produce, and its sales value, are proprietary.

Bait versus biotech

As biomedical LAL production ramped up in the 1990s, so did harvesting horseshoe crabs to use as bait for other species, particularly eel and whelk for foreign seafood markets. Over the past 25 years, hundreds of thousands – and in the early years, millions – of horseshoe crabs have been harvested each year for these purposes. Combined, the two fisheries kill over half a million horseshoe crabs every year.

There’s no agreed total population estimate for Limulus, but the most recent federal assessment of horseshoe crab fisheries found the population was neither strongly growing nor declining.

Conservationists are worried, and not just about the crabs. Millions of shorebirds migrate along the Atlantic coast, and many stop in spring, when horseshoe crabs spawn on mid-Atlantic beaches, to feed on the crabs’ eggs. Particularly for red knots – a species that can migrate up to 9,000 miles between the tip of South America and the Canadian Arctic – gorging on horseshoe crab eggs provides a critical energy-rich boost on their grueling journey.

Red knots were listed as threatened under the Endangered Species Act in 2015, largely because horseshoe crab fishing threatened this key food source. As biomedical crab harvests came to equal or surpass bait harvests, conservation groups began calling on the LAL industry to find new sources.

Biomedical alternatives

Many important medicines are derived from living organisms. Penicillin, the first important antibiotic, was originally produced from molds. Other medicines currently in use come from sources including cows, pigs, chickens and fish. The ocean is a promising source for such products.

When possible, synthesizing these substances in laboratories – especially widely used medications like insulin – offers many benefits. It’s typically cheaper and more efficient, and it avoids putting species at risk, as well as addressing concerns some patients have about using animal-derived medical products.

In the 1990s, researchers at the National University of Singapore invented and patented the first process for creating a synthetic, endotoxin-detecting compound using horseshoe crab DNA and recombinant DNA technology. The result, dubbed recombinant Factor C (rFC), mimicked the first step in the three-part cascade reaction that occurs when LAL is exposed to endotoxin.

Later, several biomedical firms produced their own versions of rFC and compounds called recombinant cascade reagents (rCRs), which reproduce the entire LAL reaction without using horseshoe crab blood. Yet, today, LAL remains the dominant technology for detecting endotoxins in medicine.

A sample of horseshoe crab blood. Florida Fish and Wildlife Commission, CC BY-NC-ND

The main reason is that the U.S. Pharmacopeia, a quasi-regulatory organization that sets safety standards for medical products, considers rFC and rCR as “alternative” methods for detecting endotoxins, so they require case-by-case validation for use – a potentially lengthy and expensive process. The FDA generally defers to the U.S. Pharmacopeia.

A few large pharmaceutical companies with deep pockets have committed to switching from LAL to rFC. But most drug producers are sticking with the tried-and-true method.

Conservation groups want the U.S. Pharmacopeia to fully certify rFC for use in industry with no extra testing or validation. In their view, LAL producers are stalling rFC and rCR approval to protect their market in endotoxin detection. The U.S. Pharmacopeia and LAL producers counter that they are doing due diligence to protect public health.

Change in the offing

Change may be coming. All major LAL producers now have their own recombinant products – a tacit acknowledgment that markets and regulations are moving toward Limulus-free ways to test for endotoxins.

Atlantic fisheries regulators are currently considering new harvest limits for horseshoe crabs, and the U.S. Pharmacopeia is weighing guidance on recombinant alternatives to LAL. Public comments will be solicited over the winter of 2024, followed by U.S. Pharmacopeia and FDA review.

Even if rFC and rCR don’t win immediate approval, we believe that collecting more complete data on horseshoe crab populations and requiring more transparency from the LAL industry on how it handles the crabs would represent progress. So would directing medical companies to use recombinant products for testing during the manufacturing process, while saving LAL solely for final product testing.

Making policy on complex scientific issues across diverse agencies is never easy. But in our view, incremental actions that protect both human health and the environment could be important steps forward.

Kristoffer Whitney, Associate Professor of Science, Technology and Society, Rochester Institute of Technology and Jolie Crunelle, Master's Degree Student in Science, Technology, and Public Policy, Rochester Institute of Technology

This article is republished from The Conversation under a Creative Commons license. Read the original article.

--

Read Also

The FDA no longer mandates all drugs to be tested on animals before being tested on humans

[femmeidiot]

Pls share your list of 20 celebrity nemesi

I’ve had this ask in my drafts for like a day because I was having trouble thinking of all my one sided beefs oh god idk if I can actually do a full 20 off the top of my head shit okay here we go: Ed Sheeran, camila cabello, Adam Levine, Blake Shelton, sia, Jennifer Lopez, Shawn mendes, Angelina Jolie, rebel Wilson, Adele, aishjsid oh god I’m sure there’s more.

[mercaritee]

Charles Wesley Godwin April 18-2024 The History In Toronto ON poster t-shirt

Charles Wesley Godwin April 18-2024 The History In Toronto ON poster t-shirt, hoodie, tank top, longsleeve

Unlike mob wives, mob girlfriends are a little more playful, a little more seductive. She’s yet to have a Sunday dinner with her family and so hasn’t yet traded in her in-object jumper for the Charles Wesley Godwin April 18-2024 The History In Toronto ON poster t-shirt and I love this animal-in-print button ring. However, where they fit in is the impeccable taste in jewelry and the preference for speed in men. Angelina Jolie and her 15-year-old daughter Vivienne Jolie-Pitt are the winners of the award for best mother-daughter bonding activity. Last summer, Jolie revealed that she had hired Vivienne as her assistant for her latest production, a musical adapted from S.E. Hinton’s young-adult novel The Outsiders on Broadway.

While Jolie went for a bit of glamor in a chic Yellow Silk Dress and Camel-colored Robe (perhaps an Atelier Jolie special?), Vivienne arrived in a navy utilitarian jumpsuit — must is a nod to the Charles Wesley Godwin April 18-2024 The History In Toronto ON poster t-shirt and I love this main characters of The Outsiders — fitting. by composer and lyricist Justin Levine. She finished the look with a pair of beat-up Converse sneakers.

Buy this shirt:  Charles Wesley Godwin April 18-2024 The History In Toronto ON poster t-shirt

Home:  Mercaritee

[sonyclasica]

BANDA SONORA

"STAY GOLD"

DE LA GRABACIÓN DEL REPARTO ORIGINAL DE THE OUTSIDERS

La nueva canción cuenta con las voces de Sky Lakota-Lynch y Brody Grant.

Mira el videoclip de "Stay Gold" AQUÍ

Consíguelo AQUÍ

Sony Masterworks Broadway, junto con los productores The Araca Group, American Zoetrope, Olympus Theatricals, Sue Gilad & Larry Rogowsky y Angelina Jolie, estrenan el nuevo tema "Stay Gold" de la próxima Grabación original del reparto de Broadway de The Outsiders - A New Musical: ESCÚCHALO AQUÍ.  "Stay Gold" cuenta con las voces de Sky Lakota-Lynch (Johnny Cade) y Brody Grant (Ponyboy Curtis), con música y letra de Jamestown Revival (Jonathan Clay & Zach Chance) y Justin Levine. El videoclip que lo acompaña está protagonizado por Sky y Brody en el estudio de grabación, intercalado con imágenes del memorable viaje del reparto a Tulsa, Oklahoma, también conocido como el lugar de nacimiento de The Outsiders: MÍRALO AQUÍ.  

"Stay Gold" llega tras el estreno del tema "Great Expectations", interpretado por Brody Grant, que ya está disponible en todas las tiendas digitales AQUÍ.

El estreno en Broadway de The Outsiders, el nuevo musical basado en la novela de S.E. Hinton y la emblemática película de Francis Ford Coppola, arrancó el sábado 16 de marzo, antes de su estreno el jueves 11 de abril en el Bernard B. Jacobs Theatre (242 West 45th Street, NYC).

En Tulsa, Oklahoma, 1967, Ponyboy Curtis, su mejor amigo Johnny Cade y su familia Greaser de "marginados" luchan contra sus rivales acomodados, los Socs. Este emocionante nuevo musical de Broadway navega por las complejidades del autodescubrimiento mientras los Greasers sueñan en quién quieren convertirse en un mundo que quizá nunca los acepte. Con una música original de gran dinamismo, The Outsiders es una historia de amistad, familia, pertenencia... y la constatación de que todavía hay "mucho bien en el mundo".

El reparto de The Outsiders está encabezado por Brody Grant como Ponyboy Curtis, Sky Lakota-Lynch como Johnny Cade, Joshua Boone como Dallas Winston, Brent Comer como Darrel Curtis, Jason Schmidt como Sodapop Curtis, Emma Pittman como Cherry Valance, Daryl Tofa como Two-Bit, Kevin William Paul como Bob y Dan Berry como Paul. La compañía también incluye a Jordan Chin, Milena J. Comeau, Barton Cowperthwaite, Tilly Evans-Krueger, Henry Julián Gendron, RJ Higton, Wonza Johnson, Sean Harrison Jones, Maggie Kuntz, Renni Anthony Magee, SarahGrace Mariani, Melody Rose, Josh Strobl, Victor Carrillo Tracey, Trevor Wayne.

Las entradas ya están a la venta en Telecharge.com, llamando a Telecharge al 212-239-6200 y en persona en la taquilla del Teatro Bernard B. Jacobs. Para más información, visita www.OutsidersMusical.com.   

The Outsiders cuenta con libreto de Adam Rapp con Justin Levine, música y letra de Jamestown Revival (Jonathan Clay & Zach Chance) y Justin Levine, supervisión musical, orquestación y arreglos de Justin Levine, coreografía de Rick Kuperman & Jeff Kuperman y dirección de Danya Taymor.  

The Outsiders cuenta con escenografía de AMP con Tatiana Kahvegian, diseño de vestuario de Sarafina Bush, diseño de iluminación de Brian MacDevitt, diseño de sonido de Cody Spencer, diseño de proyección de Hana S. Kim, Diseño de Efectos Especiales de Jeremy Chernick y Lillis Meeh, diseño de pelucas y cabello de Alberto "Albee" Alvarado, Diseño de Maquillaje de Tishonna Ferguson, especialista en Efectos de Sonido de Taylor Bense, Consultor Creativo, Jack Viertel. Dirección musical y orquestaciones adicionales de Matt Hinkley. El casting es de Tara Rubin Casting/Xavier Rubiano, CSA.

The Outsiders está producido por The Araca Group, American Zoetrope, Olympus Theatricals, Sue Gilad & Larry Rogowsky y Angelina Jolie. La dirección general es de 321 Theatrical Management. 

Entre los coproductores figuran Betsy Dollinger, Jonathan & Michelle Clay, Cristina Marie Vivenzio, The Shubert Organization, LaChanze & Marylee Fairbanks, Debra Martin Chase, Sony Music Masterworks, Jamestown Revival Theater, Jennifer & Jonathan Allan Soros, Tanninger Entertainment, Tamlyn Brooke Shusterman, Geffen Playhouse/Howard Tenenbaum/Linda B. Rubin, Kevin Ryan, Mistry Theatrical Ventures, Galt & Irvin Productions, Tulsa Clarks, Paul Liljenquist, Bob & Claire Patterson, Voltron Global Media, James L. Nederlander, Warner Bros. Theatre Ventures, The John Gore Organization, Independent Presenters Network, Stephen Lindsay & Brett Sirota, Jeffrey Finn, Playhouse Square, Sue Marks, Indelible InK, Lionheart Productions, The Broadway Investor’s Club, Starhawk Productions, Distant Rumble, Green Leaf Partnership, Michael & Elizabeth Venuti, Leslie Kavanaugh, Deborah & Dave Smith, Belle Productions, Chas & Jen Grossman, Miranda & Sahra Esmonde-White, Rungnapa & Jim Teague, Michael & Molly Schroeder, Casey & Chelsea Baugh, James L. Flautt, Jon L. Morris, Becky Winkler, William Moran Hickey Jr. & William Moran Hickey III, Oddly Specific Productions, Melissa Chamberlain & Michael McCartney, Rachel Weinstein, Wavelength Productions, Rob O’Neill & Shane Snow, Eric Stine, Cornice Productions y La Jolla Playhouse.

El estreno mundial de The Outsiders fue producido por La Jolla Playhouse, Christopher Ashley, director artístico y Debby Buchholz, directora gerente, en marzo de 2023.

CONECTA CON THE OUTSIDERS

WEBSITE | FACEBOOK | INSTAGRAM | THREADS | TIKTOK | YOUTUBE

[eurekaspringshq]

welcome to eureka springs, ANDREA LEVINE, DENVER COULSON & SOL CASTRO-GIBBS. angelina jolie, cindy kimberly & mason gooding are now taken !! please send us a message within 24 hours to receive the link to the discord.

( cindy kimberly / 20 /cisfemale/she/her. ) i heard that DENVER 'DENNY' COULSON is a WAITRESS AT NIGHTINGALE STRIP CLUB they have lived in town for ALL HER LIFE i also heard that they are ORGANIZED, CREATIVE but also BLUNT, HARD-HEADED. there’s a rumor they HAVE STARTED MAKING MONEY ONLINE but you haven’t hear it from me. ( Lynn. she/her. 24. mst. )

( angelina jolie / 53 / cisfemale/she/her. ) i heard that ANDREA LEVINE is a/an HOMEMAKER. they have lived in town for 10 YEARS. i also heard that they are CARRING, CAPTIVATING but also IMPULSIVE, SARCASTIC. there’s a rumor they MIGHT BE PUTTING HER FAMILY IN DEBT WITH HER RECENT SHOPPING ADDICTION, but you didn’t hear it from me. ( Lynn. she/her. 24. mst. )

( mason gooding / 25 / male/he/him. ) I heard that SOL CASTRO-GIBBS is a/an FIREFIGHTER. they have lived in town for HIS WHOLE LIFE. i also heard that they are CLEVER, DEDICATED but also VAGUE,PASSIVE. there’s a rumor they WENT ON A TWO YEAR BENDER WITH SOME PEOPLE FROM COLLEGE IN THE BACK OF A VAN BEFORE COMING HOME, but you didn’t hear it from me. ( Lynn. she/her. 24. mst. ) 

[leanstooneside]

Polish Hammer

• REBECCA ROMIJN'S LIFE-SIZE CHEEK

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[boricuacherry-blog]

The freedom to be herself is something Fefe Dobson, singer of "Bye Bye Boyfriend" and "Miss Vicious" says. Dobson turned down a development deal at 15 when record executives dubbed her "Brandy Spears" (as in Norwood and Britney).

"She's black, but she's got this pop, white voice. That's how they looked at it," Dobson recalls, as she pets her fluffy purse-sized pomeranian named Trailer Party, who is curled up on a patch of grass beside her. Thankfully, Jay Levine and James Bryan McCollum from Canadian duo Prozzak were working on their own music in a studio next door, and needed a female vocalist for the pop rock track, "Get A Clue." It was everything Dobson had been looking for. She was done trying to live up to the misguided expectations of out-of-touch music execs. "I went to lunch with the label and turned them down," she says. "I was offered money and I knew that would help my family... my mom's a single mother and we were in a very tough situation. But I just knew that my career would be over before it started if I didn't follow my instinct. I made sure I ate the free lunch first though."

"I was pissed off about a lot of things when I was younger," the Toronto born singer says. "I still have a lot of rage. A lot of rage. I never did anger management because I wrote music. That was my anger management."

Dobson grew up Scarborough, Ontario in a "very angry household." Dobson was raised a single mother with her three siblings, all of whom are white. Her parents split before she was born (she has family in Jamaica on her dad's side who she has never met, including her uncle, famous former Olympian Donald Quarrie). "There was a lot of tension. I walked on eggshells ever since I was a little girl," Dobson says. "I was trying to find my identity while realizing I was different in my own household. "There were moments when I felt like I didn't fit in, or I felt like my color wasn't being celebrated in my home. I didn't feel beautiful. I felt like I was comparing myself all the time. I don't blame anyone in my home for that. But, that's how I felt."

Dobson recalls little things, like her mom not knowing how to comb her curly hair. She found a haven in the music shared in her house - from her mom's Phil Collins and Bob Marley records to her older sister's Nirvana and Guns N' Roses cd.

Music was also a refuge at school. Dobson says she was picked on a lot at Wexford Collegiate School for the Arts in Scarborough. (Other notable alumni include Nina Dobrev and Shamier Anderson.) As one of her former bullies would tell her when she ran into her years later, Dobson was an "easy target" because she was "so emotional." Casually dropping that one day Justin Timberlake was going to know her name probably didn't help, although that did eventually come true. Shortly after blowing off those execs, Dobson landed a record deal with Island Def Jam and her first major tour at 18, opening for none other than Justin Timberlake. "I'm a little girl from Scarborough, and all my dreams are staring me in the face," she says of that time. But it didn't come without complications.

Dobson recalls the time during the appearance on the now-defunct German music station VIVA, when a VJ asked her point blank: "What's its like being Black?" Dobson scoffs at the absurdity of the question, but remembers feeling uneasy in the moment. Then there was the U.S. art for her second single, "Take Me Away." The image was a sketch of Fefe's face - outline only. "There was no pigment," she says. "I never thought about it when I was younger, but now I think it was to not shock people." In other words, they wanted audiences to think she was a white girl. "Yeah, it looked like Angelina Jolie," she laughs.

Dobson takes me back to the first time she saw Avril Lavigne on TV. It was 2002 and the Napanee, Ontario native was debuting her music video for her first single, "Complicated." It was just weeks before Dobson was planning to drop her first single. "I was like, 'Damn it!' because I thought that the vibe was similar," she says. "It was just like, man, I'm not going to compete with this girl. She's blonde, she's pretty, she's skinny. I got booty, I got my muscular legs. I thought, do my Dickies even fit me that way, like they fit on her?"

The rest is music history. As Macleans put it a few years later, "Unlike like Avril Lavigne, Fefe never managed to make the leap to overnight stardom." As progressive as Canadians pretend to be, this country favors white rock acts, too. Dobson has only ever been nominated for two JUNO awards: Breakthrough Artist of the Year (which went to Feist) and Pop Album of the Year (which Lavigne took home) in 2005. "You can't take anything away form how talented she is," Dobson says. "She's an amazing writer and she's had hit after hit. And we actually got to kick it a few times and she's really cool." She pauses. "But again, I was 'different,' and she fit in a mould. In that genre, I made no sense at that point. It scared people."

Black women are used to instilling fear just by daring to exist, and Dobson was inadvertently attempting to disrupt the careful appropriation of an entire genre of music. Of course, the industry was terrified. But Dobson was afraid, too. "I was always fearful I wasn't cute enough or pretty enough," she says. Even though Trixie Smith, Sister Rosetta Tharpe, Ma Rainey, Big Mama Thornton, Tina Turner (who Dobson played in an episode of American Dreams) and Macy Gray, to name just a few, had come before her, Dobson says her experience on the charts was lonely. "I didn't know who to look to. I didn't look like Ashlee Simpson, or Avril, or whoever," she says. "Now, as an adult, it's like, Damn right, I didn't! I am a beautiful woman. But then I didn't know how to do my hair. Makeup artists would make me look crazy."

In these moments, when whiteness messes with your confidence, the key is community. And hers was one of her best friends, Anastasia "Stacey" Gordon. They've known each other since high school. "Stacey definitely let me know I was beautiful and helped me a lot with navigating through the craziness and overwhelming moments over the years," Dobson says.

One of those overwhelming moments was when Dobson's sophomore album Sunday Love, which was supposed to be released in September 2005, was scrapped and she was dropped by her label after the first single, "Don't Let It Go To Your Head," didn't chart well. "It was heartbreaking," Gordon says over the phone. "When you think about being 'shelved,' it's being put back and not given the time and space to grow. That's common among black women in this industry. Specifically as a Canadian, Fefe has gone through uncharted territory. She really was a trailblazer. But at the time, I had to keep reminding her that it didn't mean she wasn't good enough."

But that's exactly how Dobson took it. Writing sessions with Cyndi Lauper and Joan Jett were left unfinished when the album got shelved, and she felt like a failure. When Dobson's "champion" Lyor Cohen, the music exec who had signed her, left Island Def Jam, she was dropped shortly after. She moved back to Toronto "devastated."

Sunday Love would eventually be released independently in 2006 (and eventually given a digital re-release in 2012) but it wasn't until a year later that everything changed. Dobson happened to turn on MuchMusic to see a still-Disney Miley Cyrus singing "Start All Over," an upbeat, bold leftover Sunday Love track. Another Sunday Love song, "As A Blonde," would go to Selena Gomez in 2009. "It was a blessing for me," Dobson says of watching other artists sing her songs. "I realized then that I wasn't shit." Asked if it was frustrating that it took white girls singing her music for her to believe in herself again, she says, "I mean...it's kind of fucked up!" She looks like she's realizing it for the first time. "But, it triggered something in me and I started writing again."

Enter the Joy era. Dobson re-signed with Island Def Jam in 2009 and came back with a vengeance, releasing the eventual platinum singles "Ghost" and "Stuttering."

"I was a different person at that point, and that's why I named the album Joy. I had dealt with a lot of the demons of being dropped, my family life, heartbreak," she says. "Joy was an album of healing." While both emotions are necessary for healing and growth, joy can be as much an act of rebellion and resistance as rage. "I just always feel like I'm coming back from the dead," she says. "I'm like the scene in the movie where the hand punches through the dirt like, "I'm back!"

It's been over a decade since Joy, and while Dobson has been working steadily since (her latest single "White Line Runaways" was featured in the 2020 indie darling film Unpregnant) she's re-entering the pop landscape at perhaps the perfect time. Olivia Rodrigo's juggernaut SOUR has critics asking "Is Pop Punk Back?" (Bustle even named Dobson as one of the album's biggest sonic influences), and Willow Smith is teaming up with Avril Lavigne for a new song. "There were times when I hit a wall [in my career] and I thought, Damn. It's just not my time," Dobson says. "But now, knowing that I had such an impact, the timing was the way it should have been. That was my fate."

Dobson is a self-described "care bear" when it comes to love, so it's no surprise that she believes in fate - both in her professional and personal life. Dobson has been living in Nashville with her husband, rapper Yelawolf (she calls him by his government name, Michael) while she works on her new material. Dobson recently announced on the Black Girl Songbook podcast that she and Yelawolf were "getting a divorce right now" but now, she declares that they are very much still married. "I am so in love with love that it's bad and good for me," she sighs. "It has made me make some great choices. And it's made me make some very bad choices." When asked if she could clarify, the most she gave was a vague answer about how going through 2020 was "a test" for their relationship. "I'll leave the rest for the album," she says coyly.

[perezhilton]

Get it, cougar! All the Angelina Jolie details HERE!

[omisteriodasduasirmas]

[tabloidtoc]

Life & Style, March 23

Cover: Angelina Jolie destroys Brad Pitt’s world

Page 1: Photo Flash -- Jennifer Aniston and her dog Clyde urging people to vote 

Page 2: Contents, a correction to the story about Keanu Reeves being engaged

Page 4: The Top 10 Dolce & Gabbana Looks -- Lupita Nyong’o, Blake Lively, Kylie Jenner, Jennifer Garner, Sofia Vergara 

Page 5: Elle Fanning, Margaret Qualley, Mindy Kaling, Gugu Mbatha-Raw, Greta Gerwig 

Page 6: Twinning -- Mariah Carey vs. La La Anthony, Cobie Smulders vs. Elizabeth Banks, Bella Hadid vs. Hailee Steinfeld 

Page 8: Adam Levine was forced to apologize to fans after showing up late to a concert in Chile and putting on a lousy and disrespectful show when his band Maroon 5 finally did show up

Page 10: Heidi Klum wants to be treated like a bigger star than Sofia Vergara on America’s Got Talent which means a bigger dressing room and a driver and she gets to keep her seat next to Simon Cowell even though Sofia has been the highest paid actress on TV for the past eight years, Jessica Simpson’s slimdown secrets 

Page 12: Amber Heard just wants to move on with her life but Johnny Depp’s lawsuit makes it nearly impossible

Page 13: Justin Bieber’s big comeback is a bust and he expected his tour to sell out within hours and he couldn’t have been more wrong, Sofia Richie’s father Lionel Richie isn’t fond of her boyfriend Scott Disick but her mother Diane Alexander loves Scott despite the 15-year age difference, VIP Style -- Dak Prescott (pictured), Lebron James and Anthony Davis, Tiffany Haddish (pictured), Bob Saget and Kelly Rizzo, Jerry Harris, Brooke Shields and Martha Stewart (pictured), Jhene Aiko, Naomi Watts (pictured) 

Page 14: The Week in Photos -- Kanye West and daughter North at Yeezy Season 8 fashion show 

Page 16: Justin Bieber scares David Beckham on Ellen DeGeneres

Page 17: Jimmy Fallon and Tom Brady and Julian Edelman 

Page 18: Coyote Peterson brought a baby wallaby to Stephen Colbert, Janina Gavankat held on tight to Ben Affleck at the premiere of The Way Back, Today’s Hoda Kotb and Savannah Guthrie and Al Roker and Carson Daly and Natalie Morales and Peter Alexander and Jenna Bush Hager took a trip to Universal Studios in Orlando 

Page 19: Joe Jonas and Sophie Turner out in LA, Celine Dion and Montreal Canadiens mascot Youppi

Page 24: Stars Behaving Badly -- Brooke Burke took her top off while sailing in the Dominican Republic, Justin Bieber grabs himself on the Miami set of his new video, Rachael Ray

Page 26: Say What?! Robert Pattinson reminiscing about landing the part of beautiful Edward Cullen in Twilight, Kaia Gerber, Drew Barrymore, Gwyneth Paltrow on daughter Apple, Chris Pratt on the habit that annoys wife Katherine Schwarzenegger 

Page 28: Chris Pratt and Katherine Schwarzenegger expecting 

Page 29: How Jimmy Fallon saved his marriage, John Legend and Chrissy Teigen have dramatically different ideas on what the perfect date night is 

Page 30: Cover Story -- Brad Pitt’s amazing year culminating in an Oscar rubbed ex Angelina Jolie the wrong way -- she thinks he’s using his divorce and his drinking issues and their kids to drum up support and she’s not buying it and doesn’t think the courts should either and she wants full custody of their children

Page 34: Jennifer Lopez and Alex Rodriguez’s wedding is off -- one year after their engagement J.Lo puts the brakes on her big day with A-Rod 

Page 36: George and Amal Clooney leading separate lives -- after more than five years of marriage George and Amal seem to be at a breaking point 

Page 38: Inside Queen Elizabeth and Prince Harry’s private sit-down -- over a four-hour lunch at Windsor Castle Harry and his grandmother finally clear the air 

Page 42: Who Lives Here? Meg Ryan 

Page 44: Entertainment 

Page 45: Star Review -- Quincy Brown, As Seen On-Screen -- the olive-green jacket Peter Weber wore during the hometown dates on The Bachelor is Cole Haan’s Diamond Quilted Snap Jacket for $298 

Page 48: Fashion 4-1-1 -- Winnie Harlow’s spring footwear collection with Steve Madden, Olivia Palermo’s first RTW collection 

Page 49: Elizabeth and James lands at Kohl’s 

Page 50: Style Crush -- Kristin Cavallari 

Page 52: Diva or Down-to-Earth? Down-to-earth Ariel Winter carries her own packages, diva Gigi Hadid employs a styling crew

Page 54: Social Stars Posts of the Week -- Kylie Jenner and BFF Stassie Karanikolaou, Debra Messing and her dog Henry, Alec Baldwin and his kids, Hailee Steinfeld on Sesame Street 

Page 55: Guy Fieri, Jon Bon Jovi and Prince Harry, Blake Shelton and Gwen Stefani and her son Apollo, Tan France 

Page 56: Horoscope -- Pisces Reese Witherspoon, They’re Not Together But They Should Be -- Pisces Brooklyn Beckham and Virgo Kaia Gerber 

Page 58: Made Ya Look -- Joe Manganiello and Ozzy Osbourne and Kelly Osbourne at Ozzy’s Global Tattoo + Album Listening Party 

Page 60: What I’m Into -- Stassi Schroeder 

[libramc]

🦋 Indicators of FAME in a BIRTH CHART 🦋

part one

warning: remember, to precisely determine fame potential you need to have more than one of these placements, I would say at least three or four of them. I'll make other parts of this series though, so don't consider exclusively this post.

ruler of the 11th house in the 11th house

the 11th house rules achievements, as well as fame. people with the ruler of the 11th house in the 11th house can get extremely famous, this is the hollywood type of fame. in fact, celebrities who have this placement are globally well-known: angelina jolie, johnny depp, al pacino, lauren jauregui, kylie jenner... to check if you have this placement, look at the 11th house in your birth chart. which sign does the cusp fall in? let's suppose it's virgo. if you have virgo in your 11th house, then you must have mercury placed there, as mercury rules virgo and hence the 11th house. if you have pisces, neptune should be in the 11th, if it's sagittarius then it's jupiter and so on.

neptune in the 1st house, neptune conjunct ascendant, ascendant in pisces

I noticed that many celebrities have prominent neptune in their charts. first of all, neptune is the planet of art in all of its forms. people with this placement are usually naturally skilled in artistic fields, hence they could get famous for their singing or dancing skills, or even for acting. next, neptune rules dreams and illusions, and celebrities aren't what they seem after all. we see them as higher, perfect people with totally different lives from ours. yet, it's obviously not true, they're humans just like us, and we're aware of it after all. despite that, we still keep idealizing them and judge them from what we're able to see. in fact, models also have prominent neptune in their charts, exactly for this reason. last but not least, neptune also rules images, covers, and hence someone with prominent neptune may often be featured on magazines, ads, social media, etc. examples: ariana grande, ellen pompeo, marylin monroe, billie eilish, whitney houston, anne hathaway, eminem, tom cruise, scarlett johansson, paul mccartney, freddie mercury...

personal planets in the 10th house

our personal planets are the sun, the moon, mercury, venus and mars. having them in our 10th house, especially if conjunct the midheaven, is a common placement in celebrities' birth charts. in fact, having a planet in a house means that we make that trait of ours more visible, it is the focus of our life. the 10th house rules career and reputation, so you do the math. the planet you have in the 10th house also describes the career you'll pursue. for example, actors will most likely have mercury (words, communication) or mars (action, movement, charisma), like selena gomez, marylin monroe, kathy bates, jessica lange, etc. a singer will have mercury (words, lyrics) and perhaps the moon (feelings, emotions) like adele, celine dion, lady gaga, christina aguilera, billie eilish, jim morrison, chris brown, liam payne...

leo sun, moon, rising or midheaven

leo is aquarius' sister sign. hence, it loves being in the spotlight. leos naturally crave attention and compliments, they feel comfortable being at the centre of attention. they're also blessed with an incredibly strong charisma that makes people attracted to them. in addition, they're gifted with creativity as well. just think of some of the most successful and famous celebrities out there: sandra bullock, kylie jenner, jessica lange, daniel radcliffe, lucy hale, blake lively, will smith, adam levine, nick jonas...

part of fortune in the 2nd, 5th, 8th, 10th or 11th house

as you can imagine from its name, the part of fortune indicates a point in your life where you're naturally skilled, where you're able to make the best fortune. in the second house, the part of fortune brings easy money, and we all know that most of the time fame makes one extremely rich. the fifth house is leo's natural house, and hence it rules creativity, drama and entertainment; an individual with their part of fortune in the 5th house may be naturally inclined towards creative outlets and being in the spotlight. the 8th house is another money house, even though it's a fame that is caused more by others. that is, if you have this placement, your #1 fortune would be your fans. also, many people with this placement are recognized as sex symbols, which influences their fame a lot. as for the part of fortune in the 10th house, it is the house of career, bringing natural ease and luck at work. last but not least, the 11th house rules fame and goals; people with their part of fortune in this house are the most dedicated to their goals, and they have the chance to achieve great fame and success for their achievements. examples: timothée chalamet, kurt cobain, angelina jolie, johnny depp, billie eilish, bill gates, gwyneth paltrow, zendaya, adriana lima, kobe bryant, mariah carey, sophia loren, vin diesel, brad pitt, steve jobs, amy winehouse, j.k. rowling...

ruler of the 10th house aspecting neptune

the 10th house is the house of career. having it in pisces, or having the ruler of it aspecting neptune is an indicator of artistic fame. the stronger aspects are the hard ones, hence having neptune conjunct, square or opposite the ruler of the midheaven is a major sign of fame and arts in a career. examples: jessica lange, sarah paulson, brad pitt, sandra bullock...

🦋 follow me for more 🦋

@libramc xx

[only-johnny-deppp]

TBT: 13 years ago, on June 1, 2008, Johnny attended and was awarded twice at the 2008 MTV Movie Awards, at the Universal Amphitheatre, in Universal City, Los Angeles, California.

On that day, Johnny was nominated and WON in two categories (If it’s hard for our shy Johnny go on stage to accept and speech one time, imagine twice).

Actor Brendan Fraser presented and announced his win on “Best Villain”  category for his role as Sweeney Todd in “Sweeney Todd: The Demon Barber of Fleet Street”, while Steve Carell, Dwayne Johnson, and Anne Hathaway announced his “Best Comedic Performance” win for his role as Captain Jack Sparrow in “Pirates of the Caribbean: At World's End”.

On the “BEST VILLAIN” he was competing against: Topher Grace for his role as “Eddie Brock / Venom” in Spider-Man 3, Javier Bardem for his role as “Anton Chigurh” in No Country for Old Men, Angelina Jolie for her role as “Grendel's mother” in  Beowulf and Denzel Washington for his role as “Frank Lucas” in American Gangster.

 On the “BEST COMEDIC PERFORMANCE” he was competing against: Amy Adams for her role as “Giselle” in “Enchanted”, Jonah Hill for his role as “Seth” in “Superbad”, Seth Rogen for his role as “Ben Stone” in “Knocked Up”, Adam Sandler for his role as “Charles Todd "Chuck" Levine” in “I Now Pronounce You Chuck and Larry”.

> Speeches: 

#1) Accepting the “Best Villain Award”:

“Popcorn! Thank you… (chuckles while audience screams) I am I'm not really sure how this happened because you can ask anybody I'm not a very funny person… Not nothing remotely fun, but that's very, that’s very… (chuckles while audience screams) Hi, how’re you doin’? This is, that’s very sweet. Thank you so much for this and thanks to everybody involved and see you ‘round.”

 #2) Accepting the “Best Comedic Performance” Award:

“Thank you very much. Wow! Two times in one night night. That’s nutty, That’s nutty… (bless you darling, bless you – he says to a fan) Hey, uh, wow, I have to thank all you who voted for me. It's really a great honor. Thank you for voting for me thanks for sticking with me on this very obtuse and strange road. And I’m… Hi (chuckles) I’m not particularly eloquent at the moment, but thank you so much. Thank you very, very much.”

Ps. During his speech the audience went literally “nutty” (crazy) and shouted the entire time.

> Johnny at the MTV Movie Awards.

This marks, until that day, Johnny’s 4th MTV Movie Award, but his 7th and 8th nomination for a award after the 1994 double nomination on “Best On-Screen Duo” and “Best Comedic Performance” (this one shared with Mary Stuart Masterson) for his role as Sam and Sam and Joon in “Benny & Joon”, the triple nomination in 2004 on “Best Comedic Performance”, “Best Male Performance” and “Best On-Screen Team” (this one shared with Orlando Bloom) for his role as Captain Jack Sparrow in “Pirates of the Caribbean: The Curse of the Black Pearl”, and the 2007’s “Best Performance” nomination for his role as Captain Jack Sparrow in “Pirates of the Caribbean: Dead Man's Chest”. But this was Johnny’s 3rd MTV Movie Award that he won after the 2004 and 2007 “Best Performance” awards for his role as Captain Jack Sparrow.