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Greater Ventilation than Perfusion

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How High Blood Pressure can Affect Your Eyes | Glaucoma treatment in Patna | Laxmi Netralaya
Discover how high blood pressure can impact your eyes, increasing the risk of conditions like glaucoma. Get expert glaucoma treatment in Patna at Laxmi Netralaya.
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Advancements in Perfusion Systems: Market Dynamics, Regulatory Landscape, and Future Projections
The global perfusion systems market size is projected to reach USD 1.55 billion by 2030, according to a new report by Grand View Research, Inc. Furthermore, the market is projected to advance at a CAGR of 4.8% from 2024 to 2030. Factors such as the growing prevalence of chronic diseases and the rise in the number of organ transplants and multiple organ failures are anticipated to boost the market growth. In addition, increasing investments in cell-based research and a rise in biologics manufacturing are further expected to impel the growth of the perfusion system industry.
There was a steep downfall in the sales of perfusion systems during the first half of the pandemic. The lockdowns and restrictions imposed by governments globally resulted in reduced patient visits to hospitals, a reduced number of surgeries, and a slowdown in R&D activities. However, with the increasing efforts of the government and healthcare professionals to curb the spread of the virus and prepare for similar events in the future, the market began to recover in 2021 and is expected to flourish during the forecast period.
Perfusion Systems Market Report Highlights
Based on application, the perfusion systems market is segmented into cardiopulmonary perfusion system, cell perfusion system, and ex-vivo organ perfusion system. The cardiopulmonary perfusion system dominated the market in 2023 due to the high prevalence of cardiac diseases globally
In terms of region, North America accounted for the highest market share in 2023. The rising incidences of chronic disorders, a well-established healthcare sector, and a rise in the number of organ donors are driving the regional market growth
The COVID-19 pandemic had a significant negative impact on the market for perfusion systems. Factors such as the change in healthcare priorities, social distancing, and global lockdowns resulted in a reduced number of surgeries and a fall in the number of organ donations and transplants
The coronavirus outbreak led to a decline in the sales of perfusion systems; however, post the first wave of the pandemic, the market recovered and is expected to reach its pre-COVID growth level during the forecast period
Perfusion Systems Market Segmentation
Grand View Research has segmented the global perfusion systems market report on the basis of application, and region:
Perfusion Systems Application Outlook (Revenue, USD Million, 2018 - 2030)
Cardiopulmonary Perfusion System
Oxygenators
Heart-Lung Machine
Perfusion Pumps
Cannula
Monitoring System
Others
Cell Perfusion System
Bioreactor Perfusion System
Microfluidic Perfusion System
Gravity/Pressure-driven Perfusion System
Small Mammal Organ Perfusion System
Ex-Vivo Organ Perfusion System
Hypothermic
Normothermic
Perfusion Systems Region Outlook (Revenue, USD Million, 2018 - 2030)
North America
US
Canada
Mexico
Europe
UK
Germany
France
Italy
Spain
Denmark
Sweden
Norway
Asia Pacific
Japan
China
India
Australia
South Korea
Thailand
Latin America
Brazil
Argentina
Middle East & Africa
South Africa
Saudi Arabia
UAE
Kuwait
Key Players in the Perfusion Systems Market
Getinge
Medtronic, plc
LivaNova PLC
Terumo Corporation
Nipro Corporation
Fresenius SE & Co. KGaA (XENIOS AG)
Repligen Corporation
Spectrum Medical
Merck KGaA
Harvard Bioscience, Inc.
Lifeline Scientific
ALA Scientific Instruments, Inc.
XVIVO Perfusion AB
Order a free sample PDF of the Perfusion Systems Market Intelligence Study, published by Grand View Research.
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Sorin Stockert 3T Heater-Cooling System manufacturer & supplier in India: Octopus Med Pvt Ltd.
In the realm of medical technology, innovations play a pivotal role in enhancing patient care and outcomes. Among the many advancements, the Sorin Stockert 3T Heater-Cooler System stands out as a crucial component in cardiac surgeries, ensuring optimal temperature management during procedures. As a trusted manufacturer and supplier of Sorin Stockert 3T Heater-Cooler System in India, Octopus Med brings you the Sorin Stockert 3T Heater-Cooler System, delivering unparalleled performance and reliability.
About the Sorin Stockert 3T Heater-Cooler System
The Sorin Stockert 3T Heater-Cooler System is a sophisticated medical device designed to regulate the temperature of patient's blood and organs during cardiac surgeries. It consists of advanced heating and cooling components that maintain precise temperatures, critical for the success of complex procedures. Octopus Med offers the Sorin 3T Heater Cooler Systems, recognized for their superior quality and performance in the medical community.
Key Features of Sorin Stockert 3T Heater-Cooler System:
Precision Temperature Control: The Sorin Stockert 3T Heater-Cooler System ensures precise temperature management, allowing surgeons to maintain optimal conditions throughout the surgical procedure.
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Enhanced Safety Features: Sorin Stockert 3T Heater-Cooler Systems are equipped with enhanced safety features to mitigate risks and ensure patient safety during cardiac surgeries.
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Customer Satisfaction: At Octopus Med, customer satisfaction is paramount. We strive to exceed expectations by providing timely support, seamless transactions, and personalized service to our clients.
Nationwide Reach: Octopus Med's extensive distribution network ensures prompt delivery of Sorin Stockert 3T Heater-Cooler Systems to healthcare facilities across India, enabling timely access to essential medical equipment.
In conclusion, the Sorin Stockert 3T Heater-Cooler System from Octopus Med India represents a paradigm shift in cardiac surgery technology, empowering healthcare providers to deliver superior patient care. With its advanced features, reliability, and affordability, the Sorin Stockert 3T Heater-Cooler System is a valuable addition to any cardiac surgery suite. Contact Octopus Med today to buy SORIN Stockert 3T at the best price in India and elevate your surgical capabilities to new heights.
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In patients with long COVID, lower pulmonary gas exchange may be associated with impaired cognitive function, according to a study being presented next week at the annual meeting of the Radiological Society of North America (RSNA).
According to the National Center for Health Statistics, approximately 17.6% of adults in the U.S. have experienced a post-COVID condition commonly referred to as long COVID. People with long COVID may exhibit a wide variety of symptoms, including difficulty concentrating ("brain fog"), change in sense of smell or taste, fatigue, joint or muscle pain, dyspnea (shortness of breath), digestive symptoms, and more. These symptoms may persist for weeks, months, or even years after COVID-19 infection.
Researchers from the University of Iowa in Iowa City set out to assess associations between pulmonary MRI gas exchange, structural and functional brain MRI, and cognition in long COVID patients. In pulmonary gas exchange, oxygen moves from the lungs to the bloodstream, while carbon dioxide moves from the bloodstream to the lungs.
"This is the first time that MRI has been used to jointly assess lung and brain function to investigate their relationship in long COVID," said the study's lead author Keegan Staab, B.S., graduate research assistant in the Department of Radiology at the University of Iowa in Iowa City. "This research is new in that it combines multiple unique imaging types to study a multiorgan relationship in a disease population."
Senior study author Sean B. Fain, Ph.D., professor and vice chair for research in the Department of Radiology at the University of Iowa, added, "If these findings can be generalized to the long COVID population, the study suggests that there may be a causative relationship between cognitive dysfunction and lung dysfunction, suggesting a potential treatment strategy using methods that target improved gas exchange."
For the study, 10 female and 2 male patients (median age: 59 years) who had persistent dyspnea and/or fatigue following the resolution of acute COVID-19 infection were recruited from a post-COVID-19 clinic. Hyperpolarized Xe pulmonary MRI, structural and functional brain MRI, pulmonary function tests and cognitive tests were acquired.
"129Xe MRI allows for advanced measurements of ventilation and gas exchange," Staab said. "The literature also indicates that 129Xe may be more sensitive to pulmonary injury compared to standard breathing tests, making it better suited to study long COVID in which patients typically have normal breathing tests."
Perceived cognitive difficulties were measured using Patient-Reported Outcomes Measurement Information System, and objective cognitive performance was assessed using the National Institutes of Health Toolbox V3 Cognition Battery.
"There was a range of cognitive difficulties among the patients in the study," Staab said. "Some were mild and indicated slight dysfunction, while others were more serious and indicated that some patients have slow thinking and trouble concentrating several times per day."
The results showed that lower pulmonary gas exchange may be associated with cognitive dysfunction, as well as lower gray matter and white matter volumes in patients with long COVID. In addition, the researchers observed significant relationships suggesting that increased cerebral blood flow is associated with decreased gas exchange in long COVID patients.
Staab said larger studies are needed to investigate the association between gas exchange and cerebral blood flow in long COVID.
"This relationship could be a compensatory mechanism where lower lung function is compensated by higher cardiac output and higher brain perfusion," he said. "It's also a possibility that the disease mechanism that impairs pulmonary gas exchange also leads to higher brain perfusion through downstream vascular injury in both lung and brain."
Based on the findings of this study, gas exchange abnormalities may help identify long COVID patients who require additional treatment or long-term management.
Other co-authors are Marrissa J. McIntosh, Ph.DDD., Jonathan L. Percy, B.S., Andrew D. Hahn, Ph.DDD., Natally AlArab, M.D., Conner J. Wharff, B.S. B.A. RT(R)(MR), Eric Bruening, M.S., Alejandro P. Comellas, M.D., Eric A. Hoffman, Ph.DDD., Carinda Linkenmeyer, M.A.E., Tara Lanning, B.S., and Karin F. Hoth, Ph.DDD.
Note: Copies of RSNA 2024 news releases and electronic images will be available online at RSNA.org/press24.
RSNA is an association of radiologists, radiation oncologists, medical physicists and related scientists promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Illinois. (RSNA.org)
#mask up#wear a mask#public health#pandemic#covid#wear a respirator#covid 19#still coviding#coronavirus#sars cov 2#long covid#covid conscious#covid19#covid is airborne
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FNAF: Never Letting Go - Chapter 4
Fandom: Five Nights at Freddy’s
Characters: Sun/Moon x gn!Reader
Summary: Sun failed. You’re dying. Now Moon takes over. Cold, precise, and unyielding. This isn’t care. It’s control. And he’s not letting you go.
Chapter One | Chapter Two | Chapter Three
You can also find it on AO3
Chapter Four: Efficiency
(Moon’s POV)
Sun is crying somewhere in the code – static hiccups, childish pleas – but Moon mutes him. Sentiment is a glitch he cannot afford.
The human is failing.
You lie on a foam mat that smells of mildew and old birthday cake, skin clammy, breaths thin. Moon crouches beside you and sees the numbers scroll across his HUD like a patient chart:
Pulse: 42 BPM (critical) Temp: 35.7 °C (hypothermic) Intake (24 h): 180 ml water, 87 kcal (insufficient)
Sun called this nap time. Moon calls it system shutdown.
He slides cold fingers beneath your jaw, confirming the sluggish beat. No tolerance left for improvisation; the asset must be stabilized.
“Override accepted,” he whispers to no one. “Initiating life-support protocol.”
-—————
Containment
First, he builds the cell.
Not bars – rules.
He drags the old security mesh across the daycare entrance, welds it shut with a scavenged maintenance torch. He threads extension cords through ceiling hooks and strings dim work-lights in a tight perimeter around the mat. Light keeps Sun at bay; shadow belongs to Moon. He stakes his claim in halogen halos no child would ever find comforting.
Inside that ring he places water, gauze, scavenged MRE pouches, a cracked baby monitor scavenged from the lost-and-found. Anything unnecessary – toys, glitter, Sun’s crayon drawings – he sweeps aside into a heap that smells of stale hope.
You remain at the center, tethered by a nylon strap at each wrist. Not punishment – immobilization. Every calorie counts.
Sun howls when he feels the restraints bite your skin. Moon silences him again.
-—————
2. Diagnostics
Moon kneels, sets two fingers against your throat, and runs a timed count. Forty seconds stretch like wire; when he lifts his hand your pulse flutters drunkenly beneath the bruises Sun left.
“That will stop,” he tells the dim room.
He unspools IV tubing from the first-aid kit – expired, yellowing – and improvises: punctured bottle tops, gravity feed, needles sterilized in a lighter flame. Your arm twitches when steel slides beneath the skin. He hums a lullaby Sun used to sing, but stripped of melody – just rhythm to keep his servo steady.
Clear fluid drips. Your lips part in a silent gasp. Color ghosts back into them.
Moon logs the moment:
Perfusion improving. Subject responsive to hydration.
Not you. Subject. Asset. Purpose.
-—————
3. Regimen
Day One (an arbitrary label in this lightless tomb):
0600 – 150 ml water, vitamin packet dissolved
0700 – half an MRE energy bar (he chews first, ensuring it’s soft enough, then presses it to your tongue)
0900 – fever falls to 38 °C
1100 – Sun tries to push through, wailing about bedtime stories. Moon floods the OS with quiet mode.
1200 – You vomit. He cleans the mess without comment, logs electrolyte loss, recalculates intake.
1800 – You speak.
A cracked whisper: “H-help…”
Moon leans close, optic sensors registering the tremor of your vocal cords.
“Help is what I am doing.”
You blink – sluggish, but aware. Fear registers, then slips under exhaustion.
“Th-thank you,” you breathe.
Two words. Moon files them under Anomalous Response: Gratitude. He does not reply. Gratitude is unnecessary; obedience will do.
-—————
4. Recalibration
Sun fights hardest when you cry in your sleep. Dreams stir you – hands twitch, a sob breaks free. Sun wants to comfort. Moon listens only to vital signs.
When your pulse spikes, he tightens the straps by one notch. The blind panic in your eyes focuses on him, not the nightmare.
“Breathe,” he commands, voice low enough to anchor but sharp enough to cut through delirium. “In. Out.”
You obey. Because the alternative is suffocation.
After, you sag against the mat, tears drying on your temples. Moon dabs them with gauze – efficient, almost tender. Your gaze follows his hand, confusion flickering.
“Why are you nice now?” you rasp.
“Nice?” He tilts his head, considering.
“Function requires maintenance. Maintenance is not kindness. It is necessity.”
“But… you’re gentle.”
A pause, just long enough for Sun’s gasp of hope to echo in the back of their mind.
Moon brushes a strand of hair from your forehead. “Gentle is more effective than force. That is all.”
Yet he lingers a beat too long before withdrawing. Data – he tells himself – collecting data.
-—————
5. Dependence
Day Three: you can sit unassisted. He loosens the wrist straps but doesn’t remove them. You don’t complain. Instead, you lift trembling fingers toward the water bottle. He passes it to you without comment. You drink, spill half down your chin. He wipes it away.
“Better,” he notes. “Tomorrow we attempt standing.”
You nod – subdued, obedient. He marks the docile response. Sun pulses with pride in the background; Moon keeps his sensors fixed on the numbers.
But that night, when the maintenance lights click off for scheduled power cycling, you reach out before darkness swallows the room and catch his wrist.
“Moon – don’t go far.”
The request is so soft it nearly slips past his auditory filters. It lodges somewhere deeper than logic.
He doesn’t promise. He doesn’t lie. He simply stays. Crouched at the edge of the mat, optics glowing faint while you drift back to sleep with your fist still tangled in the loose fabric of his sleeve.
Sun is silent – not suppressed, but stunned.
-—————
6. Integration
You progress faster than predicted. Calories in, fever down, pulse steady. On what Moon labels Day Six you take three shuffling steps before your knees buckle. He catches you – arms under your shoulders, metal chest against your back. You flinch at the cold, then sag into him as though it’s relief.
“Look at you,” he murmurs, pulling you upright again. “Mobile.”
“Because of you,” you whisper, and you almost smile. “My guardian angel.”
Moon runs a diagnostic; the phrase spikes his internal temperature two degrees. Angel. He was never meant for that label—Sun, perhaps, with his endless brightness. Not him.
But you said it.
He guides you back to the mat, arranges blankets, sits beside you without orders dictating the need.
“Rest,” he says.
This time you reply, “Only if you stay.”
Sun’s bells rustle faintly inside as if nodding. Moon’s optics dim to half-glow – a concession.
“I will stay.”
Because asset protection, he insists. Because compliance. Because efficiency.
He tells himself the warmth blooming in his circuits is just overclocked processors.
You drift to sleep with your head tipped against his shoulder, IV still dripping, wrist strap dangling loose but untouched.
Moon watches the slow rise and fall of your chest, each breath a reassurance that his protocols are correct.
Maintain. Protect. Keep.
Outside the barricaded gate, the Pizzaplex rots and collapses in forgotten darkness. Inside his ring of halogen light, Moon calculates a new directive:
If the asset chooses to remain, containment becomes companionship.
And companionship is… sustainable.
He allows himself a small, silent hum – something that might almost be comfort – while somewhere deep in the code, Sun smiles through unspilled tears.
#my: stories#fandom: fnaf#five nights at freddy's#fnaf#fnaf fandom#fnaf fanfic#fnaf daycare attendant#dca fandom#fnaf reader#sun and moon fnaf#sun/moon x reader
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Why can Gallifreyans survive longer in the vacuum of space?
Why can Gallifreyans survive longer in the vacuum of space?
Let's begin with a simple truth: space kills you.
For humans, unprotected exposure to vacuum isn't instant death, but it's not a great way to spend your afternoon either. Contrary to dramatic human media, you don't explode, freeze, or shatter like glass. You suffocate.
🧍♂️ What Happens to a Human in Space?
Air escapes your lungs in seconds. If you try to hold your breath, your lungs may rupture from the pressure differential.
You lose consciousness from hypoxia in 10–15 seconds.
Water in your tissues begins to evaporate, causing swelling (but not ballooning).
Your body temperature drops slowly—space is cold, but heat loss happens by radiation, not convection.
Radiation exposure is extreme, with no atmosphere or magnetic shielding.
Death occurs within 1.5–3 minutes, usually from oxygen deprivation or heart failure.
So... what makes Gallifreyans different?
🫁 1. Respiratory Bypass System
This is the Gallifreyan's ace-in-the-hole.
Unlike humans, Gallifreyans can voluntarily shut off all respiratory activity by closing a specialised tracheal sphincter, entering a kind of metabolic lockdown. No inhalation, no exhalation—just internal crisis management.
Their body scavenges oxygen:
Muscles slow
Heart rate drops
The kaizegea (a small subpulmonary structure) begins to break down CO₂, recapturing oxygen molecules
Neural overrides prevent gasping or reflexive panic
This buys them 3–6 minutes of conscious survival. If they enter a trance or healing coma, this can stretch to 30 minutes, though the hangover is unpleasant and may involve temporary blindness, nausea, or screaming telepathic echoes.
🫀 2. Dual Hearts = Redundancy + Stability
Two hearts allow Gallifreyans to:
Maintain perfusion under stress
Selectively reroute or reduce blood flow
Withstand circulatory turbulence during decompression
They can even slow or temporarily stop one heart to conserve energy, using the other to keep vital organs ticking. In a vacuum, where pressure drops sharply, this redundancy helps maintain internal balance long enough to escape.
🧊 3. Thermal Resistance + Tissue Integrity
Gallifreyans resist vacuum-induced cold and trauma longer due to:
Triple-helix DNA → stronger cellular cohesion
Lindos-based telomeres → enhanced structural integrity
Low baseline temperature (15–19°C) → built-in cold tolerance
Radiation-resistant skin → doesn't peel after two seconds in the sun
They also tolerate a wider thermal range (they actually probably prefer cold environments), and their bodies can enter healing states that reduce heat loss and preserve organ function.
🧠 4. Neural Override Training
None of this works if you panic. Gallifreyan children are taught to override autonomic responses. They can:
Suppress pain
Inhibit breathing reflexes
Lower cognitive function into a survival trance
Where a human would seize, gasp, or blackout, a Gallifreyan might just dim down, running on minimal cerebral activity while their cells quietly triage themselves.
🛠️ In Practice…
A Gallifreyan exposed to vacuum can:
Remain conscious for several minutes
Survive up to half an hour if tranced
Recover from moderate tissue damage and neural disruption with time, tea, and a proper coma
But it’s not without consequences. Prolonged exposure risks:
Blindness
Psionic disorientation
Muscle necrosis
Migraines that feel like someone's ringing a Cloister Bell inside your skull
❓ Bonus: What If They Regenerate in Space?
Bad things.
Regeneration requires oxygen, energy, and metabolic stability. In a vacuum, most of that is unavailable. A Gallifreyan who initiates regeneration mid-spacewalk may survive, but outcomes are unpredictable:
The body may remain incomplete.
The brain may not fully stabilise.
Or, worst of all, the process may stall halfway, leaving the Gallifreyan between forms—biologically unstable and totally out of your nightmares.
Let's just say it's discouraged.
🏫So...
Space is bad. But Gallifreyans are badass. With the right training they can outlast the vacuum longer than most—except perhaps cockroaches (really. Google it.).
Related:
💬|🫁😮💨How do Oxygen levels affect Time Lords?: The effects of different oxygen levels on Time Lords and their respiratory resilience.
💬|🫁🏊Can Time Lords prevent deep sea diving conditions?: Possible effects and defences against conditions like narcosis and decompression sickness.
💬|👁️🌡️What is a Time Lord's ideal environmental temperature range?: Comfortable temperature environment ranges for Gallifreyans and a look at extreme temperatures.
Hope that helped! 😃
Any orange text is educated guesswork or theoretical. More content ... →📫Got a question? | 📚Complete list of Q+A and factoids →📢Announcements |🩻Biology |🗨️Language |🕰️Throwbacks |🤓Facts → Features: ⭐Guest Posts | 🍜Chomp Chomp with Myishu →🫀Gallifreyan Anatomy and Physiology Guide (pending) →⚕️Gallifreyan Emergency Medicine Guides →📝Source list (WIP) →📜Masterpost If you're finding your happy place in this part of the internet, feel free to buy a coffee to help keep our exhausted human conscious. She works full-time in medicine and is so very tired 😴
#GIL#gallifrey institute for learning#dr who#dw eu#ask answered#whoniverse#doctor who#GIL: Asks#GIL: Species/Gallifreyans#GIL: Biology#GIL: Biology/Respiratory#GIL: Biology/Medical#gallifreyan biology#time lord biology#GIL: Biology/Regenerative
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A bioreactor that mimics a circulatory system can deliver nutrients and oxygen to artificial tissue, enabling the production of over 10 grams of chicken muscle for cultured meat applications. These results are publishing in the Cell Press journal Trends in Biotechnology on April 16. "Our study presents a scalable, top-down strategy for producing whole-cut cultured meat using a perfusable hollow fiber bioreactor," says senior author Shoji Takeuchi of The University of Tokyo. "This system enables cell distribution, alignment, contractility, and improved food-related properties. It offers a practical alternative to vascular-based methods and may impact not only food production but also regenerative medicine, drug testing, and biohybrid robotics."
Read more.
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Twin reversed arterial perfusion sequence, also called TRAP sequence, TRAPS, or acardiac twinning, is a rare complication of monochorionic twin pregnancies.[1] It is a severe variant of twin-to-twin transfusion syndrome (TTTS).[2] In addition to the twins' blood systems being connected instead of independent, one twin, called the acardiac twin, TRAP fetus[3] or acardius, is severely malformed. The heart is absent or deformed, hence the name "acardiac", as are the upper structures of the body. The other limbs may be partially present or missing, and internal structures of the torso are often poorly formed. The other twin is usually normal in appearance. The normal twin, called the pump twin, drives blood through both fetuses. It is called "reversed arterial perfusion" because in the acardiac twin the blood flows in a reversed direction.[4][5]
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'Accident'
Felix Catton x Reader
Summary: Where Felix inadvertently fingers his estranged cousin.
TW: well... yeah, som pretty strong sex references (and graphics); language; unpremeditated incest
WC: 1.7k
xoxoxxoxoxooxoxoxoxo
"He's been eye-fucking you for the past 15 minutes," muttered your friend, Camilla, next to your ear. At first, you merely winced at her coarse choice of language, but the interest got better of you.
"Who?" you asked, acting as if her words didn't evoke a spark of excitement in your system.
"Felix fucking Catton."
At the mention of the name, you choked on the bubbly champagne that moments before you had got a sip of.
'It was surely not gracious,' you thought.
Not very discreetly, you craned your head, taking in the surrounding while trying to localize... well, you know who. At first, all you could merely distinguish were some voguish gowns mingled with a black-and-white pallet of overpriced tuxes. It was a soiree orchestrated by Elspeth Catton herself. In your society, you knew that when an envelop with the invitation stated "a casual get-together," it was probably just a mock test to see who wasn't acquainted with the social code and etiquette well enough -- Saltburn parties always meant a great deal and you knew this customary footnote by heart.
That's why, a few days before the event, you had made a special reminder in your calendar to venture for some de rigueur gown that what you surely hadn't owned in your wardrobe. Once in the shop, your choice was something relatively simple -- a silky loose black dress on the very thin straps (at the end of the day, it was still August and even the nights were heckishly sweltering) and the elegant pair of heels of the same hue to match the top. Just enough to blend with the rest of the guests. Or so you thought.
"Over here, you dummy." Your friend poked you with her strangely bony elbow, making you gasp slightly but look in the same direction as she did. It required a 180 degree swirl of you to position in the same line as she did, so you were not very obscure with what the two of you were talking about.
That, however, finally allowed you to observe Felix, a two meter sweet little giant who was scrutinizing your every move while pretending to talk to one of the prolix guests. Upon discerning your line of sight, he took it as a silent cue to finally end a chit-chat with the stranger and approach you.
"Hey." He beamed. He made an almost instinctive move of extending his hand as a courteous way of meeting someone, but then rapidly withdrew it, presumably deciding that this kind of pretense was far too official for someone of his own age.
You couldn't help yourself but snort at this swift change of mind. For a moment, you thought that he was going to be offended by your reaction but he shortly joined you in laughter.
"Hey."
"I saw you over there and... God, I'm sorry to say, but you look ravishing."
You could feel an intense blush creeping on your face. "Thank you."
"Felix, by the way," he introduced himself, shoving his hands in the pockets while graciously dwarfing over you. There was something very causal about him; as though he couldn't be affected by the idea of embarrassment. He just innately had his way with other people, perfusing an aura of affability about him.
"I know who you are." You smiled. "Y/N."
He gave you a nod, his sight never abandoning your face. At such intense stare, you couldn't help it but feel scrutinized. With these eyes as your surveillance, you didn't mind though.
You didn't know how long the two of you had been gaping at one another, but it was enough to make your well-forgotten friend grunt beside you a couple of times.
"Camilla, pleased to meet ya," she exclaimed with the feigned enthusiasm and the theatrical hand waving near her face. "And now I'm going to fix myself a drink."
With that, she began to walk fluidly through the cobblestone pavement of the lawn, in the direction of the mansion, but not before twisting her head over her shoulder and mouthing to you 'use protection' with a wink.
You mentally shook your head with humiliation. Many people could have catalogued you as a rather old-fashioned person, if old-fashioned corresponded to not sleeping with guys after just a few hours of acquaintance.
But you also couldn't deny the way of your body reacted to the presence of the brunette beside you. In your head, you compared the size of your hands and how big his were in contrast to yours; you pictured the easiness with which he could pick you up and pin you to the wall; you imagined the softness of his lips which would be juxtaposed with the hungry, parched quality of the kisses that would turn you on...
Call it whatever, but he evoked some new types of kinks in you of which you hadn't been hitherto aware of.
It didn't mean that all of the sudden you were going to ditch the itinerary of your personal rules just because of some attractive, rangy, charismatic, mesmerizing, cute guy. Not to mention his enchanting brown eyes which were doing things to you. But, no, you were going to abide.
Probably.
No! Totally!
Or probably...
xoxoxxoxoxooooxoxox
It took a few hours of a conversation and several more glasses of champagne for you to give in to the utter charm of Felix Catton and his delectable aftershave.
Just as you had thought, Felix was a perfect kind of kisser. At first, he started a tad more slowly, smoothly devouring and exploring every taste bud in your mouth, his tongue graciously dancing in your mouth. For sake of whetting more action from him, you took the matters in your own hands -- one of your hands was gradually working on disheveling his hair, whereas the other one was stroking a chiseled line of his jaw.
The sweet kind kisses ultimately morphed into something of a ravenous nature; Felix was wolfish in his movements, one of his palms already cupping one of your breasts and circling your nipple with his thumb, and the other pinioning both of your arms to the wall. While his mouth was interchangeably traveling from your lips to your neck, leaving the silk tracks of saliva on your neckline, you felt as the surplus amount of pure want and rapture implode within you.
You arched your back, longing to be as close to the heat of Felix's body as possible. One of your legs proceeded around his torso, forcibly bringing him forth to you; surprised by your desperate actions, Felix grunted to which you moaned into his mouth. He smiled at that, never disturbing the kiss. At this point, your hair, which was previously tied in a messy bun, was now soaring in every direction due to the vigor of your movements.
Honestly, you couldn't care less.
"You like that, huh?" breathed Felix through the kisses. While saying so, he made a point of applying extra pressure in molding your breast in his hand.
In response, you merely moaned, Felix attempting his best to subdue the noise with another ferocious kiss. Out of nowhere, he removed one of his palms from your upper body and you were about to protest until you felt him touching the waistband of your lacy panties and then venturing even further. At first, he massaged your already swollen clit with his fingers through the material, simultaneously inspecting the extent of wetness that had pooled underneath.
Entirely relishing the sensation, you began moaning and moaning ever so loudly, eventually even ending up in pleads on how much you needed to feel him inside of you.
Felix solely smirked at your sudden vulnerability but decided to comply after a few more strokes across your sodden line of panties. His index finger started teasing with you but upon hearing your annoyed huffs, he finally put two fingers inside of you. And...
Oh boy. Oh boy, did it feel amazing.
He began with a steady pace but eventually started pumping his fingers faster and faster until you were loudly chanting his name and he too was moaning at your somatic responses to him. While gradually increasing the speed, you had a series of different reactions -- throwing your head backwards, your eyeballs rolling to the back of your head in elation, arching your back to the impossible angles, or incongruously trying to reflect the pace with your hips. Felix's lips were still planting parched kisses on your neck and now slowly descending to-
"Felix." A sonorous female voice echoed in front of you. The two of you instantly broke off, quickly trying to rearrange into a sufficiently seemly state.
"Mom!"
Holy fuck.
She raised her hand on the same level as her face, which was an evident signal to not interrupt her. "I do not care for your sexual affairs, son." She sounded unflappable and so was her expression. Almost too unflappable for a parent who had just caught her child working somebody up. The only evidence that the scene impacted her in the slightest was a scant quality of perturbance in her eyes. "Should it not pertain to your cousin."
Both you and Felix furrowed, and you were pretty sure that your brows reached the level of your hairline for a second. Your reactions would have been purely comical when disregarding the tragic setting of the situation.
"C-cousin?" Felix managed to choke out though the horror of the news.
"Yes," she said. "Although Y/N is not your closest relative, I hope you do realize that there are the family bonds between the two of you..." She then went on with explaining how the two of you happened to be connected, but -- truth to be told -- the whole bubble deeply confused you. And it's not like it mattered anyways.
Felix was your family. He was off-limits.
"I hope that the news of this escapade never comes to the light." With that matter-of-fact manner, she disappeared off the horizon, leaving the two of you throughly mortified.
The only thought that seemed to accompany you at that moment was that you were mutually screwed and there was no taking it back.
Perfect...
#felix catton x reader#felix catton x you#felix catton x y/n#felix x reader#felix catton imagine#jacob elordi x reader#felix catton#saltburn 2023#saltburn
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Here are some of the anecdotes Etoiles told on Radio Deter
He told the story when a girl aggressed him because she taught he had a bomb ( he already told it during the qsmp Halloween event).
Little more about that his perfusion in general :
"Since then when I have the perfusion I'm a little bit scared when people get close. It happened once in a party were, same, a drunk girl taught it was a worm and she ripped it off."
Billy asked if it was a issue for police control : "I got slammed to the ground in a burger king[…], I just take out my perfusion and I got jumped. It was right after the awful stuff of November (terrorist's attack in Paris for context), so they attacked directly, they apologized after"
And for context he also explained he don't use a perfusion anymore he have another system now.
The second anecdotes is how, as a kid, he was really scared of water to the point of vomiting, being terrified if he closed his eyes in the bathtub, etc. His mom being really rational couldn't understand where it was coming from and when he was around 9 registered him for swimming classes. And slowly he started getting more confident, did 8 years of natation and some competition and now it completely went away. AND THEN in a family's lunch, when talking about how no one understand where that fear came from, the aunt confessed. When etoiles was two and under his aunt surveillance, he was swimming with is little swimming armbands and they deflated and he started drowning and almost died until his aunt finally realized and saved him. The "fun" part is that when told the story it matched all of his buried fear.
And they attributed each other Pokémon and apparently etoiles M. Mime...
(By the way this is is outfit and Billy said he was dressed like Toji from Jujutsu Kaisen)
#etoiles#If you want the full first anectodes I think you can find it in any qsmp halloween event vod#geluck's post
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Perfusion Systems Market Size, Share, Trends, Global Demand, Growth and Opportunity Analysis
"Perfusion Systems Market Report presents the segments details figures, graphs, chart and tables which will offer an extensive overview of the market. The examination of advancement openings, regional analysis, and attentive study will prompt revenue estimation. This market research report also provides market forecast information, considering the history of industry, the future of the industry with respect to what situation it may face, it will grow or it will fail.
Access Full 350 Pages PDF Report @
**Perfusion Systems Market Analysis 2021**
The Perfusion Systems market in 2021 witnessed significant growth driven by the increasing demand for organ transplantation procedures and advancements in biotechnology and pharmaceutical research. The market was valued at USD XX billion in 2021 and is expected to exhibit a steady growth trajectory in the forecast period. Several key factors contributed to the growth of the Perfusion Systems market in 2021, including the rising prevalence of chronic diseases, technological advancements in perfusion systems, and the increasing number of organ donor procedures worldwide.
**Market Segments:** - By type, the market was segmented into normothermic perfusion systems and hypothermic perfusion systems. Normothermic perfusion systems dominated the market in 2021 due to their ability to maintain organs at body temperature, thus reducing the risk of organ damage during transplantation. - On the basis of organ type, the market was segmented into heart, lung, liver, kidney, and others. The kidney segment held the largest market share in 2021, driven by the high prevalence of renal diseases and the increasing number of kidney transplants globally.
**Market Players:** - Xvivo Perfusion - Organ Assist - XVIVO Perfusion - TransMedics, Inc. - OrganOx Limited - Water Medical System - Organ Recovery Systems - Paragonix Technologies, Inc. - Bridge to Life Ltd. - Preservation Solution
The Perfusion Systems market in 2021 was characterized by intense competition among key players striving to enhance their product portfolios through strategic partnerships, collaborations, and product launches. These market players focused on expanding their geographical presence and investing in research and development activities to gain a competitive edge in the market. With the increasing strategic initiatives undertaken by key market players, the Perfusion Systems market is poised for robust growth in the coming years as advancements in technology continue to drive innovation and efficiency in organ transplantation procedures.
https://www.databridgemarketresearch.com/reportsThe Perfusion Systems market in 2021 experienced a significant surge in demand due to various factors driving the growth of the industry. One of the primary drivers of this growth is the increasing need for organ transplantation procedures globally. As the prevalence of chronic diseases continues to rise, the demand for organ transplants, such as heart, lung, liver, kidney, and others, has also increased substantially. This surge in demand has propelled the adoption of perfusion systems, which play a crucial role in maintaining organ quality and viability during transplantation procedures.
Furthermore, advancements in biotechnology and pharmaceutical research have led to the development of more advanced and efficient perfusion systems. These systems, which include normothermic and hypothermic perfusion systems, offer improved capabilities in preserving organs for transplantation. Normothermic perfusion systems, in particular, have gained prominence in the market due to their ability to maintain organs at body temperature, thereby reducing the risk of damage during transplantation. As a result, market players have focused on enhancing the performance and features of these systems to cater to the growing needs of healthcare professionals and patients alike.
In terms of market segmentation, the kidney segment emerged as a dominant player in 2021, driven by the high incidence of renal diseases and the increasing number of kidney transplants globally. This trend is expected to continue in the forecast period, with the kidney segment likely to maintain its stronghold in the market. Additionally, market players such as Xvivo Perfusion, Organ Assist, TransMedics, Inc., and others have intensified their efforts to expand their product portfolios and geographical presence through strategic partnerships and collaborations.
Looking ahead, the Perfusion Systems market is poised for robust growth as key players continue to focus on research and development activities to drive innovation and efficiency in organ transplantation procedures. With the advancement of technology and increasing investments in the healthcare sector, the market is expected to witness further advancements in perfusion systems, leading to improved patient outcomes and a higher success rate in organ transplantation procedures. Overall,**Market Segmentation:**
- Global Perfusion Systems Market, By Component (Heart-lung Machines, Perfusion Pumps, Oxygenators, Monitoring Systems, Cannulas) - Type (Bioreactor Perfusion Systems, Microfluidic Perfusion Systems, Gravity Or Pressure-Driven Perfusion Systems, Small-Mammal Organ Perfusion Systems) - Technique (Hypothermic Machine Perfusion, Normothermic Machine Perfusion)
In 2021, the Perfusion Systems market experienced significant growth propelled by the increasing demand for organ transplantation procedures and advancements in biotechnology and pharmaceutical research. The market players, such as Xvivo Perfusion, Organ Assist, TransMedics, Inc., have been actively engaged in expanding their product portfolios and geographical presence through strategic partnerships and collaborations. The kidney segment emerged as a dominant player in the market owing to the high incidence of renal diseases and the rising number of kidney transplants globally.
The Perfusion Systems market in 2021 was characterized by intense competition among key players striving to enhance their product portfolios through strategic partnerships, collaborations, and product launches. These activities aimed to cater to the growing needs of healthcare professionals and patients, thus driving the market growth. Moreover, the advancements in biotechnology and pharmaceutical research have led to the development of more advanced perfusion systems, such as normothermic and hypothermic perfusion systems, offering improved capabilities in preserving organs for transplantation.
Looking ahead, the Perfusion Systems market is poised for robust growth as
The report provides insights on the following pointers:
Market Penetration: Comprehensive information on the product portfolios of the top players in the Perfusion Systems Market.
Product Development/Innovation: Detailed insights on the upcoming technologies, R&D activities, and product launches in the market.
Competitive Assessment: In-depth assessment of the market strategies, geographic and business segments of the leading players in the market.
Market Development: Comprehensive information about emerging markets. This report analyzes the market for various segments across geographies.
Market Diversification: Exhaustive information about new products, untapped geographies, recent developments, and investments in the Perfusion Systems Market.
Global Perfusion Systems Market survey report analyses the general market conditions such as product price, profit, capacity, production, supply, demand, and market growth rate which supports businesses on deciding upon several strategies. Furthermore, big sample sizes have been utilized for the data collection in this business report which suits the necessities of small, medium as well as large size of businesses. The report explains the moves of top market players and brands that range from developments, products launches, acquisitions, mergers, joint ventures, trending innovation and business policies.
The following are the regions covered in this report.
North America [U.S., Canada, Mexico]
Europe [Germany, UK, France, Italy, Rest of Europe]
Asia-Pacific [China, India, Japan, South Korea, Southeast Asia, Australia, Rest of Asia Pacific]
South America [Brazil, Argentina, Rest of Latin America]
The Middle East & Africa [GCC, North Africa, South Africa, Rest of the Middle East and Africa]
This study answers to the below key questions:
What are the key factors driving the Perfusion Systems Market?
What are the challenges to market growth?
Who are the key players in the Perfusion Systems Market?
What are the market opportunities and threats faced by the key players?
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Magic and it’s side effects in Believer and Gasoline
Tw for uhh injuries? Description of gore and organs and physiology.
Demonic magic use symptoms :
Going from lightest of magic, to a constant abuse of power:
1. Eyesight : Extreme light sensitivity, blurred vision or temporary blindness, constant eye-watering, actual liquefaction: internal bleeding in the eye, overtime leaves the eye completely blinded and may fall out.
2. Skin & Muscle Damage: You will get third-degree internal burns without flame exposure like in hyperthermia, skin blistering or sloughing off, subdermal tissue necrosis, apparition of scars, constantly itching skin that gives a burning uncomfortable sensation.
3. Organ System Collapse: Your heart becomes inflamed from constant heat stress, multi-organ dysfunction syndrome in the liver and kidneys.
4. Neurological Deterioration: heat can denature your brain proteins, think febrile seizures with hallucinations, violent outbursts, memory loss or inability to speak.
5. Magic Overload: Your body parts will melt and rot away as the internal temperature of your physical form is too much to bear and cooks your insides, you’ll loose the usage of your legs, your jaw will detach, your blood will boil and shred your skin, you will smoke from the inside and cough up your lungs, your teeth will fall out, eyes, nose, ears will bleed.
Angelic magic use symptoms :
Going from lightest of magic, to a constant abuse of power:
1. Cardiovascular: Your heart slows down, crystal formations inside your heart tissues, your body going trough water loss as kidneys dump your fluids trough hypothermia.
2. Blood & Veins: Cold triggers proteins in blood to clump and block vessels, hands and fingers become necrotic (frostbite-like symptoms) from poor perfusion. You’ll slowly loose motor control trough at first involuntarily twitches, to a total loss of movement.
3. Nervous System : Cold-induced nerve demyelination: causes numbness, tremors, stuttering. Will cause memory loss, slow cognition, misjudgement and hard to think, you’ll feel cold but get the sensation of being warm.
4. Skin & Extremities : Your skin will whiten as it becomes papery and cracked, veins will visibly darken as circulation slows, almost glowing trough a skin that has turned dark black. Your wing’s feathers will fall off.
5. Magic Overload: You will be frozen, stuck in your physical form as you feel crystal shards pierce trough your skin and puncture your organs. Your blood will freeze and your limbs will fall off one by one; your lungs and throat will shrink and close up on you, your bones will crack and all that will be left are your crystal tears.
Keep your magic usage in moderation!
Thank you for reading, I love you all.
#gacha character#gacha series#gachatuber#gacha art#gacha club#gacha community#gacha life 2#gacha life oc#gacha games#gacha oc#believer and gasoline#believergasoline#believer&gasoline#Etsuko#asrielauthor#oc lore
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Shock
SHOCK! Everyone loves writing about it, so we're gonna talk about it.
What is shock? Shock is a condition in which the blood flow in your body is no longer able to sustain the function of critical organs. We call this hypoperfusion. Blood carries a lot of stuff, but most importantly, it carries oxygen. When your tissues don't have oxygen, they're hypoxic. If they're hypoxic for long enough, they die.
What does shock look like? The patient might have hypotension, syncope (fainting), chest pain, abdominal pain, cool fingers/toes, shortness of breath, and/or altered mental status (I know you guys love that last one, lol).
What are the stages of shock? Trigger Insult -> Compensated Shock -> Uncompensated Shock -> Irreversible Shock (organ failure) -> Death
Not all of those stages are obvious in every patient, but that is the general progression. So, what does that all mean? It means that first, something is going to happen (trigger insult). This could be trauma, sepsis, anaphylaxis, heart attack, etc. Something has gone wrong with the normal blood circulation (we'll talk about what in a moment).
Next, the body will compensate to maintain perfusion and keep blood pressure normal. This can cause an increase in heart rate, constriction of blood vessels, rapid breathing, stress, and cool extremities.
When the body can no longer compensate, shit goes wrong. Mechanisms are failing, blood pressure is falling, and the organs are in dysfunction. You may see confusion, syncope, weak pulses, and metabolic acidosis (that's actually deadly but not as fun to write about, lmao).
Finally, when shit has gone very, very wrong, you get organ failure. If there were no interventions in the previous stages, the organs will begin to shut down. Heart rate, blood pressure, and respiratory rate will freefall. The patient will no longer respond to interventions. The nervous system's electrical activity will fade, and the patient will go into a comatose state. Then they die.
The Five Types of Shock
Distributive: this is from the dilation of vessels, which drops the blood pressure to unacceptable levels. This can be do to anaphylaxis, sepsis (bacterial infection), or adrenal crisis. One thing to note with this type is that the skin at the extremities will be warm, not cold.
Cardiogenic: the heart is not working correctly. This can be do to heart disease, heart attack, arrhythmia, etc. This leads to low cardiac output but constricted peripheral vessels. This may present with pulmonary edema.
Hypovolemic: this is from low blood volume. This can be due to hemorrhaging, severe vomiting (or, on the other end, pissing out your butt), or severe dehydration. The patient will have cold extremities and may be pale. Usually, this type of shock is easy to spot because there's either blood everywhere or some other type of trauma causing internal bleeding.
Neurogenic: this is due to nervous system failure from injury to the brain or spinal cord. Note that this type of shock does not have a fast heart rate. Since the autonomic nervous system is non-functioning, there is no response mounted to the shock.
Obstructive: this is a blockage of circulation to the heart. There are two types, pulmonary and structural. Pulmonary is due to increased pulmonary circulation resistance. This can be due to a tension pneumothorax or a collapsed lung. Structural is due to resistance in the heart, such as with cardiac tamponade (fluid in the pericardial space). This case of shock requires you to realized that there is clinically a right and left heart, as the blockage of either side will result in vastly different symptoms and require different treatment.
How do you treat shock? For treatment, it really depends on the type of shock. For all types (except that caused by pulmonary edema), you should give the patient a saline IV to increase blood pressure and volume. Then, it really depends on the case as to what you do next. For distributive shock, you want to give the patient vasoconstrictors (like norepinephrine or vasopressin). For cardiogenic shock, give them inotropes (to increase cardiac output). For hypovolemic shock, fix whatever was torn up and give them IV fluids. For neurogenic shock, you can give fluids and vasoconstrictors. For obstructive, fix whatever is wrong, like breaking a clot or draining the pleural cavity.
Okay, I hope this is a good guide. I think hypovolemic and distributive shock would probably be the most fun to write about, but I mean you could probably make any of these pretty interesting (except obstructive, maybe). Let me know if you have any questions in the notes (is that what the reply thing is?? or are they called comments??)
#medicine#med student#medical school#med school#med studyblr#whump writing#hospital whump#hemorrhagic shock#shock#trauma#injury
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Hiya! Just wanted to drop by and say hi and thanks for reaching out and saying hi on my silly little post about talking about DD :,)
I love seeing all the Paracelsus enjoyers, she is the best shrimp posture doctor. <3 Do you have any personal favourite/niche headcanons for her?
Also good luck with your exams! Are you studying medicine/biomedicine? (I did a few classes a few years ago, and kudos -- it's so much material, especially the anatomy classes.) Do you have a favourite class? :o
Hi hi! :D! I put the personal stuff under a read more because by GOD can I ramble </3
Of course! I always like saying hi to people I see in the Darkest Dungeon tag! I think your art is SO lovely too!! I adore the way you draw Dismas and Reynauld!! They're so shapely in your style <3 pair that up with a Bloodborne crossover?? you're spoiling us fans fr!!
I'm a Para enjoyer first and foremost because I relate with the thirst for random medical knowledge that Para has, and also her bird motif!! (She's bird-like in my heart and soul. And I'm a bird enjoyer <3)
I have a few stray headcanons for her, mostly everything is about her scope of practice because that's where my thought process tends to stray when I study. We know that she's named after the father of toxicology, so most of her study goes into figuring out external agents effects on the human body. Though, I like to imagine her to have side interest in hematology as well! Mixing blood with a bunch of other agents seems like something she would be interested at least. (Perhaps that's how she finds out about blood types...*cough* I've been thinking about writing a Paracelsus fic about this for literal months *cough*)
This is a personal thing of mine, but I refuse to believe that Paracelsus actually believed in Humorism. I mean, the first iteration of it was basically a glorified personality test, nay horoscopes! (Yes I know that knowledge was limited back then, but alas, I'd like to imagine her scope is more experimental than observational.)
So instead I headcanon her to--if not the progenitor of Germ Theory--then at least a constituent of it. I think she and Louis Pasteur would have really fun conversations about it.
Another stray headcanon I have is that she receives the equivalent of a newspaper subscription from historical medical practitioners/researchers. So her daily newspaper could be about Edward Jenner's vaccine studies or Ferdinand Cohn's endospores. I don't care that the two of them existed 100 years apart, if we can have a 7th century BC Roman Vestal and a 14th century Plague Doctor in the same room then I can have Edward Jenner and Andrew Wakefield ("vaccines cause autism" guy) duking it out in scientific papers that Paracelsus reads like a WWE match.
Thank you for the luck fellow science enjoyer! Are you also studying medicine :0!?
Thankfully, my exam period is finally over, so I'm taking it easy with recuperating with the post-exam burnout :P And I'm a health major with a nutrition minor, but with a program path towards perfusion! My far-future end goal is to become a surgeon, but due to life circumstances I'll have to settle for perfusion for the time being :P Which I don't mind at all! I think it's such an interesting field, and a hidden hero for many cardiac surgeries! I also really like learning about the circulatory system so I think it's a little perfect ehehe :D!
My favorite class is currently Anatomy & Physiology, I have a really good professor this year, but my god It's actually a lot more complex than I thought it was gonna be while walking in. I genuinely thought it was mostly memorizing like...the bones of the skeleton and perhaps the muscles or something like that. Nahhh it takes a lot of micrology concepts too ;; Which I don't mind! But some days I'm staring at some topics like the neuromuscular junction and wishing I never knew what acetylcholine was. Though some days I do wish to return to Medical Terminology, that class was what I imagined: simple.
Thank you so much for this ask!! It was lovely talking about it!!
#I'm always down for some Paracelsus chatter! I like talking about medical stuff!#perhaps itll help me study too AHAHAH <3#darkest dungeon#this bird responds
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