#acne vulgaris risk factors

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South Korea Acne Vulgaris Market — Forecast(2024–2030)

South Korea Acne Vulgaris Market Overview

The South Korea anti-acne dermal patch market size is valued at USD 55.2 million in 2021 and is expected to register a compound annual growth rate (CAGR) of 7.1% from 2022 to 2030. Acne Vulgaris is a multifactorial skin disease that causes lesions on areas of the body with a large concentration of oil glands, such as face, chest, neck and back. It is a common disease of the pilosebaceous unit, involving abnormalities in sebum production, follicular epithelial desquamatin and bacterial proliferation. The disease occurs most frequently during childhood and adolescence also appear in adults. It occurs when dead skin cells, bacteria, and oil (sebum) block hair follicles. Acne vulgaris can cause psychological pressure, social withdrawal and reduced self-esteem in addition to carrying a significant risk of permanent facial scarring. There is also a rise in expenditure in the exploration of multiple alternatives to effectively treat Acne Vulgaris.

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Key Takeaways

Increasing prevalence of skin-related issues and rising awareness regarding skin care products, accelerating the demand of South Korea Acne Vulgaris.

Changing lifestyle, upsurge in cosmetic expenditure and rising awareness of disease boosts the acne vulgaris treatment market growth within the region.

Growing demand for innovative therapeutics, and rising awareness among people of South Korea is set to accelerate market growth.

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By Type — Segment Analysis

In 2019, Topical Retinoids South Korea Acne Vulgaris segment dominated the South Korea Acne Vulgaris Market in terms of revenue is estimated to grow at a CAGR of 3.2%. Skin sensitivity or irritation with use of topical retinoid is a minor challenge faced by this segment as people are apprehensive to its usage. Thus, many Korean skin care products tend to use very less or no retinol ingredients in their formulations. It is used to reduce acne as well as prevents aging, fine lines, dark spots and dull skin. Various studies conducted by Korean Society for Acne Research, have inferred that acne vulgaris is treated better by topical methods and also adapalene is used in combination with clindamycin or doxycycline for severe cases. According to International Trade Administration, South Korea is the 9th largest cosmetics market in the world. Thus, more skin care products are being produced here and their use is also high abetting towards the segmental growth of the market.

Drivers — South Korea Acne Vulgaris Market

Rise in Adoption of Skin Care Products

Growing conscious about the ingredients of skin care products and manufacturing process supports the market growth. For instance, according to a survey conducted by Philips, 44% of women in South Korea expect the use of more natural and organic ingredients rather than chemicals in skin care products. The market expansion is driven by increased demand for minimally invasive therapies combined with the fact that dermatologists tend to treat skin disorders with the use of topical applications or less invasive procedures such as lotion, creams or gels instead of surgical methods.

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Challenges — South Korea Acne Vulgaris Market

Failure of Pivotal Clinical Trials 

Failure of pivotal clinical trials for key candidates remains an impediment to the growth of South Korea Acne Vulgaris Market. Further, Off-label use of anti-acne drugs such as Diane-35 as birth-control measures lead to serious consequences such as breast cancer and venous thromboembolism (VTE) restraining the market growth. Key players in the market are also facing failures in the late-stage clinical trials that are another key factor obstructing the market growth. For instance, Olumacostat glasaretil (Dermira), SNA-001 (Sienna), XEN801 (Xenon), and JNJ-10229570 AAA (Valeant) have faced discontinuation in the recent past.

South Korea Acne Vulgaris Industry Outlook

Product Launches was the key strategy of the players in the South Korea Acne Vulgaris Industry. South Korea Acne Vulgaris top 10 companies include Bayer AG, Gladerma S.A., Pfizer Inc., Allergan, Bausch Health Company, GlaxoSmithKline Plc, Otsuka Pharmaceuticals, Jeilmedix Pharmaceutical, Kwan Dong Pharma, and Teva Pharmaceuticals.

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[skinbeautystore]

Causes and Treatment Options for Adult Acne

Causes and Treatment Options for Adult Acne

Adult acne is a common skin condition that affects many individuals. Although it is often associated with adolescence, acne can also persist into adulthood. This article will explore the causes of acne in adults and discuss various acne treatment options available to manage this condition effectively.

What is Adult Acne and its Causes?

Understanding Adult Acne Adult acne refers to the occurrence of acne in individuals over the age of 25. It can manifest as different types of acne, including whiteheads, blackheads, acne vulgaris, and pimples. It is often more persistent and may require targeted treatment to effectively manage the breakouts. Common Causes of Adult Acne Several factors can contribute to the development of acne. Hormonal changes play a significant role in triggering acne in adults. Fluctuations in hormone levels can lead to increased sebum production, clogged pores, and inflammation, resulting in breakouts. Hormonal Changes and Adult Acne Hormonal imbalances, such as those experienced during menstrual cycles, pregnancy, or menopause, can contribute to acne. These changes can stimulate the sebaceous glands to produce more sebum, which can clog the hair follicles and can worsen acne and acne flare-ups.

What are the Symptoms and Causes of Adult Acne?

Recognizing the Symptoms of Adult Acne The symptoms of acne in adults are similar to acne experienced during adolescence. These include the presence of whiteheads, blackheads, and pimples, as well as redness and inflammation around the affected areas. It typically occurs on the face, but it can also appear on the chest, back, and shoulders. Potential Causes for Adult Acne The causes of acne are multifactorial. Hormonal imbalances, as well as genetic predisposition and a history of acne, can contribute to its development. Additionally, certain lifestyle factors, such as stress, diet, and skincare routine, can cause acne and exacerbate acne breakouts. The Role of Hormones in Adult Acne Hormones, particularly androgens like testosterone, can stimulate the oil glands to produce more sebum. This excess sebum can mix with dead skin cells and bacteria, clogging the pores and leading to severe acne. Hormonal acne is often characterized by deep, nodulocystic acne lesions that can be challenging to treat.

How to Manage and Treat Adult Acne?

Effective Treatment Options for Adult Acne There are several effective treatment options available for managing acne. These include topical acne medications, oral medications, and professional treatments. How to treat acne depends on the severity of the acne and individual preferences. Moderate to severe acne will probably need medical advice while those with mild acne can effectively clear up acne with non-prescription treatments. Topical Solutions for Treating Adult Acne Topical treatment solutions containing ingredients like benzoyl peroxide, retinoid, and salicylic acid can help reduce inflammation, unclog pores, and kill acne-causing bacteria. These over-the-counter treatment type skin care products are readily available and can be incorporated into a daily skincare routine to clear acne in adults. Over-the-Counter Products for Managing Adult Acne In addition to topical solutions, there are numerous over-the-counter skincare products specifically formulated to target acne. Cleansers, moisturizers, and spot treatments containing acne-fighting ingredients can help prevent breakouts and improve the overall appearance of the skin.

Are there At-Home Treatment Options for Adult Acne?

The Importance of a Consistent Skincare Routine A consistent skin care routine is essential for managing adult aseattle6713 cne. Cleansing the skin twice daily, using gentle products, and avoiding excessive scrubbing can help maintain a healthy balance and minimize the risk of clogged pores. It is important to choose non-comedogenic products that do not clog the pores. Natural Remedies for Treating Adult Acne There are several natural remedies that may help reduce the severity of acne in adults. Tea tree oil, aloe vera, and witch hazel are known for their antimicrobial and anti-inflammatory properties, which can soothe the skin and reduce acne-related redness and irritation. Lifestyle Changes to Minimize Adult Acne Certain lifestyle changes can contribute to the prevention and management of adult acne. Managing stress levels, maintaining a balanced diet, and avoiding excessive exposure to pollutants and toxins can help improve overall skin health and minimize breakouts.

When to Seek Help from a Dermatologist?

When To Consult a Dermatologist for Adult Acne If over-the-counter products and at-home remedies fail to clear your acne or if the severity of your acne is causing significant distress, it may be necessary to seek help from a dermatologist. A dermatologist can assess the specific needs of an individual and recommend a tailored treatment regimen. The Role of Professional Treatments for Adult Acne Dermatologists can help by offering a professional acne treatment regimen that may include procedures like chemical peels, microdermabrasions, or laser therapy. These treatments can effectively target bacteria likely to cause acne, reduce inflammation, and improve skin texture and appearance. Prescription Medications for Severe Adult Acne In cases of severe form of acne, dermatologists may recommend oral medications such as birth control pills or isotretinoin. These medications can effectively regulate hormone levels, reduce sebum production, and prevent acne formation. Read the full article

[dermexpertise]

For moderate-severe acne, topical and systemic therapies are mainstays, with procedures as complementary treatments.

Systemic options include oral antibiotics, hormonal therapies, and isotretinoin. Choice depends on acne severity/type, patient factors, and preferences. Systemics are typically combined with topicals, except isotretinoin monotherapy.

Topical retinoids and benzoyl peroxide are commonly combined with systemics. Retinoids treat comedonal and papulopustular acne and maintain responses. Benzoyl peroxide prevents antibiotic resistance.

Other topical agents can be used if first-line options are unavailable, poorly tolerated, or ineffective. Procedures like injections, peels, surgery, and light therapy are supplementary.

Isotretinoin is effective for severe, stubborn, nodular acne but has risks, so it's not first-line for mild cases. Treatment lasts months and may initially worsen acne.

When using any acne treatment, be aware of potential side effects, contraindications, and patient preferences. Discuss concerns and questions with patients.

In summary, moderate-severe acne involves systemic and topical therapies, with procedures as needed. Treatment choices are tailored to acne severity, patient factors, and preferences to improve outcomes while minimizing risks.

For more details on acne treatment options, visit dermatology resources like our website. This summarizes key considerations in the management of more advanced acne vulgaris.

[dermaorganicsblog]

5 - Secrets of Acne-prone Skin.

Acne-prone skin is a major problem that most people face in their lives.  It makes your skin dull, full of blemishes and bumps. Acne can sometimes be painful as well. Acne-prone skin can be caused by various factors, skin type being one of them. For this, using the right products like organic turmeric soap can be beneficial in managing acne. Here are five secrets of acne-prone skin and how organic turmeric soap can help.

1) Excess sebum production.

One of the major causes of acne is that you might be having overactive sebaceous glands. These can lead to excess sebum (oil) production, clog pores, and acne breakouts. The best secret for managing this type of acne is to use Turmeric herbal soap. This soap contains many natural antibacterial properties that can help control the growth of acne-causing bacteria and reduce sebum production in these glands. Hence if you are serious about managing the acne and preventing it from returning you need to have turmeric soap for acne.

2) Inflammation is a major cause of acne.

Inflammation plays a significant role in acne development. High inflammation of the skin is the breeding hub for acne. Using Turmeric soap for acne is the key here. As it contains a compound called curcumin, which possesses anti-inflammatory properties.Turmeric herbal soap can help reduce redness, swelling, and inflammation associated with acne, promoting calmer skin that is free from acne and its marks.

3) Bacterial infection is a major cause of acne.

The major cause of acne is a bacteria namely,  Propionibacterium acnes (P. acnes) this bacterium commonly resides on the skin and can contribute to acne development when it proliferates. The acne caused by this bacteria is severe and can lead to redness and puss. It's medically termed acne vulgaris.

Buy turmeric soap as a means of defence against this bacteria as it has  antimicrobial properties. That can help inhibit the growth of P. acnes bacteria, reducing the risk of bacterial infection and subsequent acne breakouts.

4) Hyperpigmentation and scarring.

Acne breakouts can leave behind hyperpigmentation (dark spots) and scars, affecting the overall appearance of the skin. Not only do they have a damaging effect on the skin, but these scars can also lower your confidence as well. For this also you need to buy turmeric soap as it contains natural skin-brightening properties that can help fade acne scars and even out the skin tone, resulting in a more even complexion.

5) Antioxidant protection.

Antioxidants protect you against acne. Turmeric is rich in antioxidants that can help protect the skin from oxidative stress caused by free radicals. By neutralizing these free radicals, organic turmeric soap can assist in preventing damage to the skin, supporting its overall health and reducing the likelihood of acne breakouts.

When using organic turmeric soap for acne-prone skin, it is essential to follow a consistent skincare routine. Cleanse your face with soap twice daily, morning and evening, and ensure that you moisturise your skin afterwards. Additionally, it is advisable to patch-test the soap on a small area of your skin before regular use to check for any adverse reactions. If you have severe acne or underlying skin conditions, it is recommended to consult a dermatologist for personalized advice and treatment options.

[rohans18]

Keratolytic Agents Market Analysis and Forecast to 2029

Global Keratolytic Agents Market, By Indication (Psoriasis, Dry Skin, Acne Vulgaris, Warts, Dandruff, Others), Dosage Form (Shampoo, Gel, Solution, Face Wash, Lotion, Creams, Others), Agents (Urea, Salicylic Acid, Lactic Acid, Alpha Hydroxy Acids, Propylene Glycol, Others), Route of Administration (Topical, Others), End-Users (Hospitals, Homecare, Speciality Centres, Others), Distribution Channel (Hospital Pharmacy, Online Pharmacy, Retail Pharmacy) – Industry Trends and Forecast to 2029

The consistent Keratolytic Agents market report analyzes many points that help businesses to solve the toughest questions in less time. The major topics of this business report are global growth trends, market share by manufacturers, market size by type, market size by application, production by region, consumption by region, company profiles, market forecast, value chain and sales channels analysis, opportunities & challenges, threat and affecting factors. The report gives market definition in the form of market driving factors and market restraints which helps estimating the demand of particular product depending on several aspects. Keratolytic Agents market survey report studies the global market status and forecast, categorizes the global market size, market value & market volume by key players, type, application, and region.

Key Players

Hoffmann-La Roche Ltd. (Switzerland)

Mylan N.V. (U.S.)

Teva Pharmaceutical Industries Ltd. (Ireland)

Sanofi (France)

Pfizer Inc. (U.S.)

GlaxoSmithKline plc (U.K.)

Novartis AG (Switzerland)

Merck & Co., Inc. (U.S.)

Allergan (Ireland)

AstraZeneca (U.K.)

Johnson & Johnson Private Limited (U.S.)

Hikma Pharmaceuticals PLC (U.K.)

 Browse More Info @ https://www.databridgemarketresearch.com/reports/global-keratolytic-agents-market

One of the principal objectives of a high-ranking Keratolytic Agents industry report is to analyze and study the global sales, value, status, and forecast. The market report also analyzes the global and key regions market potential and advantage, opportunity and challenge, restraints and risks. The report assists to define, describe and forecast the market by type, application and region. It estimates the region that is foretold to create the most number of opportunities in the global Keratolytic Agents market. This market research report comprises of estimations of CAGR values which are quite significant and aids businesses to decide upon the investment value over the time period. An insightful Keratolytic Agents market report assists clients to stay ahead of the time and competition.

Key questions answered in the report:

Which product segment will grab a lion’s share?

Which regional market will emerge as a frontrunner in coming years?

Which application segment will grow at a robust rate?

Report provides insights on the following pointers:

Market Penetration: Comprehensive information on the product portfolios of the top players in the Keratolytic Agents Market.

Product Development/Innovation: Detailed insights on the upcoming technologies, R&D activities, and product launches in the market.

Competitive Assessment: In-depth assessment of the market strategies, geographic and business segments of the leading players in the market.

Table Of Content

Part 01: Executive Summary

Part 02: Scope Of The Report

Part 03:  Global Market

Part 04: Global Market Sizing

Part 05: Global Market Segmentation By Product

Part 06: Five Forces Analysis

 About Us:

Data Bridge Market Research set forth itself as an unconventional and neoteric Market research and consulting firm with unparalleled level of resilience and integrated approaches. We are determined to unearth the best market opportunities and foster efficient information for your business to thrive in the market

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[chhabrahealthcare]

Causes of Acne, Symptoms, Factors, Risk Factors and Homeopathy Treatment by dr. Chhabra Healthcare

Acne is also known as acne vulgaris. It is a skin condition or skin disease which involves the oil glands of the skin and the base of hair follicles over the skin.

So basically, this internal inflammatory skin condition causes pimples, blackheads, spots, cystic acne, and nodular acne, especially on the face, back, chin, forehead, neck, chest, upper arms, nose, and shoulders.

to know more visit here https://drchhabrahealthcare.com/

 or call here ✅ Call for #FreeConsultation at +91-9914015014, 9914015027.

[gregorylipson]

ACNE: CAUSES, RISK FACTORS, SELF-CARE AND OVER-THE-COUNTER TREATMENTS

The medical name for acne is Acne vulgaris. In textbook terms, acne is a chronic, inflammatory skin condition resulting in pimples on the skin. The most common areas for breakouts are the face, chest, upper arms and back. As per the American Academy of Dermatology publication in 2006, acne is the most common skin condition in the United States. And up to 50 million Americans are suffering from this condition yearly. Acne is common in young adults. https://www.bskin.com/Blog/Tips-tutorials/Acne:-Causes-Risk-Factors-Self-care-and-Over-The-Counter-Treatments

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Acne or Pimples Treatment. What's Up?

Acne or Pimples Treatment. What's Up? Acne or Pimples. What's Up? WATCH THESE VIDOES AND READ THE ARTICLE IF YOU SUFFERING FROM ACNE OR PIMPLES ACNE OR PIIMPLES. WHAT IS IT? ACNE OR PIMPLES TREATMENT PLAY VIDEO ACNE OR PIIMPLES. TYPES ACNE OR PIMPLES TREATMENT PLAY VIDEO ACNE OR PIIMPLES TREATMENT AT MSI ACNE OR PIMPLES TREATMENT PLAY VIDEO ACNE OR PIIMPLES TREATMENT WHAT'S UP? ACNE OR PIMPLES TREATMENT PLAY VIDEO ACNE OR PIIMPLES TREATMENT RESTESULTS (before & after) ACNE OR PIMPLES TREATMENT PLAY VIDEO Acne is one of the most common diseases with a point prevalence of up to 100% among adolescents and often persists into adulthood, with detrimental effects on self-esteem. Sixty percent of all acne cases are so-called ‘physiologic acne,’ the other 40% are those that need continuous help with a specialist to prevent physical or psychological scarring. Acne is still the most frequent primary diagnosis for visits to dermatologists. What Causes Acne or Pimples? Acne is one of the most common diseases with a point prevalence of up to 100% among adolescents and often persists into adulthood, with detrimental effects on self-esteem. Sixty percent of all acne cases are so-called ‘physiologic acne,’ the other 40% are those that need continuous help with a specialist to prevent physical or psychological scarring. Acne is still the most frequent primary diagnosis for visits to dermatologists. Acne is currently understood as a chronic inflammatory disease of the pilosebaceous unit, characterized by androgen-induced increased sebum production, follicular hyperkeratinization, inflammation, and altered adaptive immune response. Bacterial colonization by Propionibacterium acnes aggravates the course of the disease in various manners, but its role as a prerequisite of the induction of acne is disputable. What are the Types of Acne or Pimples? Noninflammatory acne is characterized by both open and closed comedo formation. The inflammatory lesions of acne originate with comedo formation but then expand to form papules, pustules, nodules, and cysts of varying severity. As the severity of the lesion progresses, nodules form and become markedly inflamed, indurated, and tender. The cysts of acne are deeper and filled with a combination of pus and serosanguineous fluid. In patients with severe nodulocystic acne, these lesions frequently coalesce to form massively inflamed complex plaques that can include sinus tracts. Acne fulminans Acne fulminans is the most severe form of cystic acne and is characterized by the abrupt onset of nodular and suppurative acne in association with variable systemic manifestations. While affected individuals often have typical mild to moderate acne prior to the onset of acne fulminans, without warning, micro-comedones erupt. These soon become markedly inflamed and coalesce into painful and oozing friable plaques with hemorrhagic crusts. The face, neck, chest, back, and arms are all affected. Ulcerated lesions can lead to significant scarring. Osteolytic bone lesions may accompany the cutaneous findings. Systemic manifestations include fever, arthralgias, myalgias, hepatosplenomegaly, and severe prostration. Acne Conglobata Severe, eruptive nodulocystic acne without systemic manifestations is termed acne conglobata. These recalcitrant lesions are part of the follicular occlusion tetrad, along with dissecting cellulitis of the scalp, hidradenitis suppurativa, and pilonidal cysts. The association of sterile pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA syndrome) is part of a related group of inflammatory disorders that includes inflammatory bowel disease, uveitis, and psoriasis. Solid facial edema An unusual and disfiguring complication of acne vulgaris is solid facial edema (Morbihan's disease) Clinically, there is a distortion of the midline face and cheeks due to soft tissue swelling. The woody non-scaling induration may be accompanied by erythema. Similar changes have been reported with rosacea and Melkersson– Rosenthal syndrome. Although fluctuations in severity are common, the spontaneous resolution does not occur. Acne Mechanica Acne Mechanica occurs secondary to repeated mechanical and frictional obstruction of the pilosebaceous outlet. Comedo formation is the result. Well-described mechanical factors include rubbing by helmets, chin straps, suspenders, and collars. Linear and geometrically distributed areas of involvement should suggest acne mechanica. Treatment is aimed at eliminating the inciting forces. Acne Excoriée (Fes Jeunes Filles) Acne excoriée des Jeunes Filles, as the name implies, occurs primarily in young women. Typical comedones and inflammatory papules are systematically and neurotically excoriated, leaving crusted erosions that may scar. Linear erosions suggest self-mutilation, and an underlying psychiatric component should be suspected. Patients with an anxiety disorder, obsessive-compulsive disorder, or personality disorder are, particularly at risk. Antidepressants or psychotherapy may be indicated in such patients. Drug-Induced Acne (Acneform) Acne lesions or eruptive acneiform lesions can be seen as a side effect of a number of medications, including anabolic steroid, corticosteroids, corticotropin, phenytoin, lithium, isoniazid, iodides, and bromides. Less often, azathioprine, cyclosporine, tetracyclines, vitamins B1, B6, B12 and D2, phenobarbital, PUVA, propylthiouracil, disulfiram or quinidine are the cause. An abrupt, monomorphous eruption of inflammatory papules and pustules is often observed in drug-induced acne, in direct contrast to the heterogeneous morphology of lesions seen in acne vulgaris. This explains why some clinicians use the term ‘folliculitis.’ When a history of prescription medication use is not elicited, a comprehensive review of all over-the-counter medications and supplements, as well as recent medical procedures, may reveal the responsible agent. Iodides are found in many cold and asthma preparations, contrast dyes, kelp, and combined vitamin-mineral supplements. Sedatives, analgesics, and cold remedies often contain bromides. Occupational Acne Exposure to insoluble, follicle-occluding substances in the workplace is responsible for occupational acne. Offending agents include cutting oils, petroleum-based products, chlorinated aromatic hydrocarbons, and coal tar derivatives. Comedones dominate the clinical picture, with varying numbers of papules, pustules, and cystic lesions. Chloracne Chloracne, the term used to define occupational acne caused by exposure to be chlorinated aromatic hydrocarbons, develops after several weeks of exposure. The following agents, found in electrical conductors and insulators, insecticides, fungicides, herbicides, and wood preservatives, have all been implicated. Prevention of exposure is integral to the safety of at-risk employees. Treatment is aimed at the vigorous removal of chemical agents at the time of exposure. Topical or oral retinoids and oral antibiotics may be necessary for therapeutic interventions. Neonatal Acne Neonatal acne occurs in more than 20% of healthy newborns. Lesions appear at about 2 weeks of age and generally resolve within the first 3 months of life. Typically, small, inflamed papules arise on the cheeks and across the nasal bridge. However, topical 2% ketoconazole and benzoyl peroxide has been shown to be effective therapies. Infantile Acne If acne presents at 3-6 months of age, it is classified as infantile. Clinically, comedo formation is much more prominent than in the neonatal form and may lead to pitted scarring. Deep cystic lesions and suppurative nodules are occasionally seen. During the first 6-12 months of life, infant boys have elevated levels of luteinizing hormone (LH) and its stimulatory product testosterone, with levels transiently equivalent to those measured during puberty. In addition, the infantile adrenal gland is immature in both boys and girls, leading to elevated levels of DHEA. At approximately 12 months, these levels normally decrease and remain at nadir levels until puberty, around 9 or 10 years of age. Testicular androgen is also minimal throughout most of childhood. Premenstrual Flare About 70% of women complain of a flare 2–7 days premenstrual. It is unlikely that any possible variation in sebum excretion during the menstrual cycle could be substantial enough to explain the flare. Possibly, flaring is related to a premenstrual change in the hydration of the pilosebaceous epithelium. Progesterone and estrogen also have both pro- and anti-inflammatory effects. Sweating and Acne Up to 15% of acne patients notice that sweating causes a deterioration in their acne, especially if they live or work in a hot, humid environment; for example, for a cook, ductal hydration may be the responsible factor. Ultraviolet Radiation and Acne Patients and doctors alike believe that natural sunlight improves acne, but there is no scientific c evidence for this belief. The cosmetic effect of tanning may be the entire explanation. Diet and Acne Dermatologists can no longer dismiss the association between diet and acne. Compelling evidence exists that high glycemic load diets may exacerbate acne. Dairy ingestion appears to be weakly associated with acne, and the roles of omega-3 fatty acids, antioxidants, zinc, vitamin A, and dietary fiber remain to be elucidated How Dermatologists Treat Acne or Pimples? Topical Retinoids & Retinoid-Based Fixed Combination  for Acne or Pimples Topical retinoids act against comedones and micro-comedones. The drawback of low cutaneous tolerability of topical tretinoin is continuously improved by new delivery systems to facilitate controlled release, including; Retin-A Micro® gel 0.1% or 0.04%, Avita 0.025% gel or cream or micronized tretinoin Atralin® Gel 0.05%. Another advantage of microsphere and micronized formulation is marked protection against tretinoin photodegradation and oxidation by BPO. Adapalene, a synthetic third-generation topical retinoid, is available as 0.1% gel, cream, solution, and recently as lotion and as 0.3% gel (Differin®). Topical tazarotene is approved for acne treatment only in the USA (Tazorac®). Recently introduced retinoid-based fixed combinations with high-quality clinical efficacy evidence include fixed combinations of tretinoin 0.025% and clindamycin phosphate 1.2% (Ziana®) and Veltin® Gel, and adapalene 0.1% and BPO 2.5% (Epiduo™, Tactuo™), representing the only fixed-dose combination product available that combines a topical retinoid with BPO. Topical Anti-microbials & Their Fixed Combinations for Acne  or Pimples Topical antimicrobials are an essential part of the therapeutic armamentarium for mild-to-moderate acne vulgaris and represent an alternative for patients who cannot take systemic antibiotics. Clindamycin, erythromycin, tetracycline, or nadifloxacin are bacteriostatic for P. acnes and have also been demonstrated to have anti-inflammatory activities. Their use as monotherapy is no longer recommended, and they should be applied preferentially in combination with BPO – an approach that also reduces the emergence of P. acnes strains that are resistant or less sensitive to antibiotics. The combination of a topical retinoid plus an antimicrobial is a rational choice because of the complementary modes of action that increase the speed of response and enhance efficacy against comedones and inflammatory lesions. At the moment, three fixed combination products of clindamycin and BPO are on the market: two containing clindamycin 1% and BPO 5% (Duac®) and Benzaclin®) and an optimized formulation of clindamycin phosphate 1.2%/BPO 2.5% aqueous gel (Acanya®). Other Topical Treatments for Acne or Pimples Azelaic acid 20% in a cream formulation has been established as an efficacious and safe topical drug for almost two decades. Azelaic acid 15% gel is approved for the treatment of rosacea in the USA, but also has approval for the treatment of acne vulgaris in Europe and recently proved efficacious in the treatment of postinflammatory hyperpigmentation in acne. Azelaic acid is currently recommended as a second-line option for the treatment of mild-to-moderate papulopustular acne and comedonal acne, or also in combination with systemic antibiotics for severe acne forms as an alternative treatment for isotretinoin. A new aqueous gel formulation of dapsone 5% (Aczone), was more effective than tazarotene monotherapy for the treatment of comedonal acne, suggesting that anti-inflammatory agents such as dapsone might effectively treat early stages of acne (both comedonal and non-comedonal) when used in combination with a retinoid. Oral Antibiotics for Acne or Pimples Systemic antibiotics are recommended in the management of moderate-to-severe inflammatory acne, after the failure of topical treatment and in acne covering large parts of the body surface. Substances reported to be effective in acne therapy are tetracycline, doxycycline, minocycline, lymecycline, trimethoprim-sulfamethoxazole, clindamycin, roxithromycin, and azithromycin, but particularly minocycline and doxycycline, with their potent anti-inflammatory effects on neutrophil chemotaxis or inhibitory effects on cytokines and matrix metalloproteinases. For this reason, they are routinely used as the first-line oral antibiotic therapy in acne. Current treatment guidelines recommend the combination of oral antibiotics with retinoids, azelaic acid, BPO, or a combination of retinoid/BPO for moderate-to-severe forms of acne. The use of sub-antimicrobial doses of antibiotics may offer promise. Instead, the primary mechanisms of action of sub-antimicrobial-dose antibiotics are anti-inflammatory mechanisms. To limit the emergence of resistant strains, the use of antibiotics should be restricted, and about indication and duration, topical and systemic antibiotic therapy should always be combined with broad-spectrum antibacterial agents (e.g., BPO), and the combination of topical antibiotic and systemic antibiotic therapy as well as antibiotic monotherapy should be avoided. Hormonal Therapy for Acne or Pimples Androgens, estrogens, growth hormone, and insulin-like growth factors play an important role in the development of acne. Various systemic hormone preparations are available for acne in female patients. These may be indicated when: standard antibiotic regimens have failed, menstrual control and/or contraception are required alongside acne therapy, and oral isotretinoin is inappropriate or not available. Topical therapy can and should be prescribed in conjunction with hormonal regimens. Potential hormonal treatments for acne include inhibitors of androgen production by the ovary (oral contraceptives) or adrenal gland (low-dose corticosteroids), androgen receptor blockers, and antiandrogens that block the effect of androgens on the sebaceous gland. Hormonal therapy represents an alternative or additional treatment regimen, especially in late-type female acne, polycystic ovary syndrome, other signs of hyperandrogenism, such as seborrhoea, androgenetic alopecia or hirsutism in combination with acne (SAHA syndrome) and in case of parallel wishes of contraception or as a requirement for systemic isotretinoin treatment. It can be combined with topical therapy or systemic antibiotics in moderate-to-severe acne forms but is not a primary monotherapy for uncomplicated acne. The combinations of Ethinyl estradiol with cyproterone acetate, chlormadinone acetate, dienogest desogestrel, and drospirenone have shown the strongest anti-acne activity. Oral contraceptives generally contain estrogen (most commonly ethinyloestradiol) and a progestin. estrogens act on the liver to increase the synthesis of sex hormone-binding globulin (SHBG), which binds testosterone and reduces the level of free circulating testosterone. Hence all oral contraceptives will potentially improve acne. In addition, oral contraceptives suppress ovulation by inhibiting the production of ovarian androgens, which results in reduced serum androgens and lower sebum production. Drospirenone is a novel progestin derived from 17á-spironolactone and as with the parent, the compound has anti-mineralocorticoid and antiandrogenic activity, making it potentially helpful in acne. Yasmin® contains drospirenone 3 mg combined with ethinyloestradiol 30 ug, and Yaz® contains the same dose of drospirenone with 20 ugs of ethinyloestradiol. Low-dose prednisolone is only to be administered at late-onset congenital adrenal hyperplasia and dopamine agonists at hyperprolactinemia. Low-dose glucocorticosteroids (i.e.2.5 mg prednisolone on waking and 5 mg on retiring) to suppress adrenal androgens, with or without a contraceptive pill, will reduce sebum production by up to 50% with a concomitant improvement in acne. Androgen Receptor Blockers for Acne or Pimples The anti-androgen CPA directly inhibits the androgen receptor and serves as a progestogen in oral contraceptives. Dianette® and Estelle 35® are oral contraceptives that ameliorate acne. It is as effective as oral tetracycline 1 g/day given over a 6-month period. The clinical efficacy of this combination can be enhanced by giving an extra 50 mg or 100 mg CPA from the fifth to the 14th day of the cycle. It is also of potential benefit in women with acne resistant to other therapies. Spironolactone is an effective treatment (it is not a contraceptive) and reduces sebum excretion by 30–75% depending on the dosage used. Its effects are dose-dependent, and it is usually prescribed at a dose of 50–100 mg daily with meals, but many women with sporadic outbreaks do well with doses as low as 25 mg daily. Flutamide is a potent antagonist of the androgen steroid. Although most commonly used in the treatments of prostatic conditions flutamide has been shown to be efficacious in several androgen-mediated problems, including acne, administered at a dose of 250 mg daily. Fatal hepatotoxicity has been reported and therefore use in acne is not generally advocated. There is concern about the potential reduction in the efficacy of oral contraceptives as a result of systemic antibiotics used in conjunction with COCs. The risk is theoretical, based on the hypothesis that broad-spectrum antibiotics reduce bacterial flora in the gut and thus interfere with estrogen absorption. Oral Isotretinoin for Acne or Pimples Oral isotretinoin exhibits activity against all major etiologic factors involved in the pathogenesis of acne. It significantly reduces the size and sebum production of sebaceous glands, normalizes follicular keratinization, and prevents the development of micro-comedones and comedones, indirectly inhibits P. acnes growth by changing the follicular milieu and upregulation of antimicrobial factors and exerts direct immunologic and anti-inflammatory activity. Isotretinoin is considered the first-choice treatment for severe papulopustular, moderate nodular, and severe nodular/conglobate acne, especially when other complicating prognostic factors are present. The rationale behind this recommendation is that the quick reduction of inflammation in acne may prevent the occurrence of clinical and psychological scarring. The recommended dose to start isotretinoin therapy is now 0.3–0.5 mg/kg for severe papulopustular acne/moderate nodular acne and 0.5 mg/kg for conglobate acne. The duration of the therapy should be at least 6 months and can be prolonged in case, of insufficient response. Side effects of isotretinoin include those of the mucocutaneous, musculoskeletal and ophthalmic systems, as well as headaches. According to currently available evidence, the prescription of oral isotretinoin is encouraged in severe acne patients who will normally experience both physical and psychological improvement of their disease. Read the full article

[questionharsha-blog]

Digest of Recent Drug Approvals

1. New Drugs Were Approved for H.Pylori Infection, Chemotherapy Induced Neutropenia

US Food and Drug Administration has recently approved Talicia (amoxicillin, omeprazole, and rifabutin) Delayed-Release Capsules for the treatment of Helicobacter pylori (H. pylori) infection in adults.

USFDA also approved Ziextenzo a PEGylated growth colony-stimulating factor indicated to reduce the incidence of febrile neutropenia in patients who underwent chemotherapy.

Click Here to read in detail about these drugs.

2. A New Drug Was Approved For Multiple Sclerosis

Vumerity consists of diroximel fumarate which is recently approved for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease.

Click Here to read in detail about Vumerity.

3. New Drugs Were Announced for Hypotension, Acne, Cystic Fibrosis

USFDA has announced the approval of Trikafta (elexacaftor, ivacaftor and tezacaftor) a triple combination regimen for the treatment of cystic fibrosis, Amzeeq (minocycline topical foam) for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris.

USFDA also announced the ready-to-use formulation of phenylephrine injection Biorphen for the treatment of clinically important hypotension resulting primarily from vasodilation in the setting of anesthesia.

Click Here for details about these drugs

4. New Drugs Were Approved For Migraine, Schizophrenia, Erythropoietic Protoporphyria

FDA has approved Reyvow (lasmiditan) with a unique mechanism of action for the acute treatment of migraine, with or without aura, in adults.

It has also approved Secuado (asenapine) the first and only transdermal patch for the treatment of schizophrenia.

Scenesse (afamelanotide) which is approved by FDA increases the pain-free light exposure in adult patients with a history of phototoxic reactions from erythropoietic protoporphyria.

Click Here to read in detail about these drugs

5. New FDA Approvals for Macular Degeneration, Osteoporosis, Acne

FDA approved Beovu (brolucizumab-dbll) injection for the treatment of wet age-related macular degeneration (AMD), Bonsity (teriparatide) Injection for the treatment of osteoporosis in people with a higher risk of fracture, and Aklief (trifarotene) Topical Cream, 0.005% for the treatment of acne.

Read more https://wcts.app/Drug

[eczemang-blog]

 Acne Rosacea Treatment - Best Recommendations

The Acne Rosacea Treatment is almost equivalent to our previous treatment recommendations. You can get the better options here on how you can possibly get yourself treated at ease. The acne rosacea is a very dangerous infection of the skin. This skin infection requires a better acne rosacea treatment and that is what we will be talking about on this very thread. Perhaps you may want to know what Acne Rosacea really is. Yeah! knowing what it is really matters on this very contest since it engineers the main anchor of this article. For we to go further to the acne rosacea treatment, let's dig this first. Because of this un-clarified matter, you may likely not comprehend or grasp anything we would be talking about here. So this apparently lead me to ask "what is acne rosacea? this question should be anchored before we talk about  Acne Rosacea Treatment.

What Is Acne Rosacea?

Now let's candidly talk about what a rosacea mean. But before that, I would want you to comprehend this matter. This rosacea seems to be similar to psoriasis but not same. So take your time to understand what makes them similar and why they differ from each other. And always remember that we are here to secure a better acne rosacea treatment. Great experts and mentors have been able to give us a specific details on this context and on the acne rosacea treatment too. Meanwhile, rosacea is simply a common chronic. This rosacea could sometimes be very progressive and dermatosis. Meanwhile rosacea can occur in adults of any ethnicity, and adversely affects patients' quality of life. Also the rosacea acne is characterized in combination by central facial erythema, symmetric flushing, stinging sensation, inflammatory lesions (papules and pustules), telangiectasias, and phymatous changes (tissue hyperplasia and nodules). The condition can be effectively controlled with therapy tailored to the specific subtype of rosacea that is affecting the patient. Topical metronidazole, sulfacetamide/sulfur, and azelaic acid are generally effective for patients with mild rosacea. Again for moderate papulopustular rosacea, combination therapy with oral tetracyclines and topical agents is the first-line choice. Acne Rosacea Treatment with a topical agent, such as metronidazole, may help maintain remission. Patients with ocular involvement may benefit from long-term oral antibiotics and metronidazole gel. Adittionally, you being referred to asubspecialist is necessary for patients who have ocular rosacea with ophthalmic complications, severe or recalcitrant rosacea, or phymatous changes. Brief Introduction To Acne Rosacea From researchers record, the rosacea has affected over 14 million people in the United States. You see the reason why we've prescribed an acne rosacea treatment. These treatments will help reduce, or even terminate the existence of this very skin problem, from the united states. It is more common in white persons but can occur in persons of other ethnicities. Rosacea is somewhat more likely to occur in women. It generally emerges when patients are in their 30s, although it can develop in younger age groups. The influence of heredity on the development of rosacea has not been well studied. However, one survey suggests that first- and second-degree relatives of patients with rosacea have a higher rate of rosacea, and persons of Irish, English, or German ancestry are more likely to develop the disease. Although this evidence is weak, it supports epidemiologic patterns that are anecdotally noted in the literature. The differential diagnosis of rosacea includes acne vulgaris, systemic lupus erythematosus, polymyositis, sarcoidosis, photodermatitis, drug eruptions (particularly from iodides and bromides), granulomas of the skin, and perioral dermatitis. The differential diagnosis of ocular rosacea may include staphylococcal and seborrheic blepharokeratoconjunctivitis, and sebaceous gland carcinoma.  Acne Rosacea symptoms In addition to all these, rosacea is a very common skin condition with characteristic symptoms and signs. These signs and symptoms includes the following; Symmetric flushing Stinging sensation Inflammatory lesions (papules and pustules) Telangiectasias on the face. Now in most cases, this may cause inflammation of the eyes and eyelids. Whereas in most patients, the central area of the face is affected so terribly. The parts of the face which could be affected is the nose, the chin, the perioral areas and the forehead.Also phymatous changes include thickened skin and large pores. Moreover, clinical findings represent a spectrum of disease with one or several predominating characteristics, including a pattern of exacerbations and relative inactivity. Also, the National Rosacea Society classifies rosacea into four sub-types. These are listed below; Papulopustular Ocular Erythematotelangiectatic and Phymatous Those are the various sub-types of this very rosacea and they shouldn't be neglected, Meanwhile, these sub-types are classified by severity based on the number of papules/pustules and plaques. Acne Rosacea Treatment There are several and numerous acne rosacea treament we will taking about here. The aim of unveiling these treatments is to make you live better and free from rosacea and other skin diseases, Topical Therapy The topical therapy is one of the best of it's kind. When you neglect this method, it simply means that you don't want to embrace quick recovery from rosacea. When we talk about acne rosacea treatment; let's not forget this topica therapy. The topical therapy rocks! Topical regimens are first-line therapies for mild papulopustular rosacea because there is less risk of adverse events, drug interactions, and antibiotic resistance. The severity of the patient's presentation helps guide the decision to initiate topical therapy alone or in combination with systemic therapy. Systemic therapy should be withdrawn when adequate response occurs Yeah! take that very method to get acne rosacea treatment and be happy once again. Drug Therapy I hardly see people talk about this very acne rosacea treatment method. Perhaps they thought that this method isn't effective or wouldn't yield a better result. But nevertheless, the drug therapy is actually one of the best. On a serious note, when we talk about acne rosacea treatment, I think we shouldn't neglect this simple method because it really matters a lot. Drug therapy should be based on rosacea classification, severity, and response to previous treatment regimens. As for acne rosacea treatment, the following may be recommended to reduce rosacea flares: Use of emollient, noncomedogenic moisturizers and mild, fragrance-free, soap-free cleansers that have a nonalkaline or neutral pH level. Avoidance of astringents and other skin care products containing alcohol, menthol, eucalyptus oil, clove oil, peppermint, witch hazel, or sodium lauryl sulfate. This will help as it is one of the acne rosacea treatment. Use of broad-spectrum sunscreen containing either zinc oxide or titanium dioxide, and wide-brimmed hats Meanwhile, the initial drug therapy for mild rosacea should include appropriate topical regimens, such as antibiotics, immunomodulators, or retinoids. First-line topical regimens (e.g., metronidazole , azelaic acid , sulfacetamide/sulfur) should be applied once or twice daily. Yeah! take this drug therapy method to get acne rosacea treatment and be happy once again. Nonpharmacologic Therapy The nonpharmacologic therapy is one of the best in the area of acne rosacea treatment. The initial therapeutic approach for rosacea, especially the erythematotelangiectatic and papulopustular subtypes, is avoidance of known triggers or exacerbating factors when possible. These factors may be specific to individual patients. The particular acne rosacea treatment rocks, don't neglect it. Did you find this content very resourceful? of do you have any question based on acne rosacea treatment? or any suggestion to render on the acne rosacea treatment? Just feel free to send us your feedback using the comment box below, thanks. Read the full article

[biomedgrid]

Biomed Grid | Wheat-gluten-desirable-or-dangerous-genes

Abstract

My opinion is issued to collect and broaden the information about gluten, or more precisely, whether its presence and properties should raise concerns. Knowledge about gluten has expanded considerably over the last dozen or so years. It is known that it is a large polymer consisting of a mixture of proteins. Gluten occurs in popular cereals such as wheat, spelt, barley, rye and oat. Works carried out by cereal breeding institutes require a continuous control of the presence of various forms of these proteins in wheat grain, because, firstly, there is a need to obtain fertile varieties with high grain quality parameters, and secondly, to improve the physical and chemical properties of farinaceous products. As it turned out, gluten, which brings many positive aspects in the breeding process of cereals, as well as in the production of bakery products, can become a cause of many problems for humans. According to many authors, apart from celiac disease, there are already over 50 other diseases, such as osteoporosis, autoimmune diseases, cancer and neurological diseases that are being associated with gluten effects.

Introduction

Gluten is a polymer composed of a mixture of at least 50 proteins [1]. There are about 20% of proteins in the endosperm of mature cereal grains such as wheat, rye, barley, triticale and oat, of which 80% are gluten proteins [2,3]. The biological role of gluten is to supply elements (carbon, nitrogen and sulfur) to germinating seeds [4]. The composition of gluten proteins in grains affects the technological quality of common wheat. The quantity and composition of gluten proteins such as gliadins and glutenins is responsible for flour baking quality in the bakery industry. These proteins constitute the “skeleton” of a kneaded dough and are responsible for physicochemical properties of gluten. Gluten in cakes is primarily responsible for flexibility and cohesion [2,3]. As it turned out, gluten that brings so much positive properties in the production process of bakery products may be the cause of many health problems.

Gluten consumed by humans most often in the form of bread and pasta is a high-calorie food. This caloric value together with the increase of glucose and insulin in the body contributes to the formation and deposition of visceral fat, most often in the regions of the abdomen, thighs and buttocks as well as diabetic complications and diseases [5].

The biochemical effect of visceral fat on the body carries a number of adverse changes. Among other things, it leads to an increase in low density lipoprotein (LDL cholesterol) responsible for the accumulation of atherosclerotic plaque, hypertension, heart diseases [6-9]. In the nervous system, it is responsible for the occurrence of temporal epilepsy [10], dementia [11], ataxia, neuropathy, gluten encephalopathy [12], worsening of autistic indices [13] and aggravation of schizophrenia [14]. In the digestive system, apart from intolerance, allergy and celiac disease, gluten [15] is the cause of increased hepatic enzyme secretion, may lead to liver inflammation, primary biliary cirrhosis and colitis and Crohn’s disease [16]. Skin symptoms of the negative effect of gluten are primarily herpetic dermatitis (Duhring’s disease) [17], acne [18], paraneoplastic syndrome, erythema nodosum, psoriasis, dermatomyositis and exacerbation of the genetic ichtiosis vulgaris (ichthyosis) [17]. It was also shown that gluten affects hair loss [19]. The influence of gluten in the female reproductive system may contribute to infertility, increased risk of low birth weight of a newborn, premature labor or habitual miscarriage [20] and increased prolactin production [21]. In addition, women suffering from celiac disease are predisposed to a shorter fertility period, caused by the later age of menstruation and a faster menopause [22]. In the case of men, gluten proteins may lead to erectile dysfunction and gynecomastia [23], caused by disturbances of estrogen production by visceral fat [24].

Symptoms in the sense organs include retinopathies, cataracts and dry eye syndrome [25], while systemic symptoms are anemia and vitamin deficiencies [26].

Unfortunately, consumption of bread and flour products carries the risk of body acidification [27]. Acidosis contributes to bone fragility, osteopenia, fractures and osteoporosis [28].

Gluten proteins contained in the endosperm of cereals also contribute to tumor formation in the human body. They may be a factor contributing to the formation of breast, prostate, lung and gastrointestinal cancers, especially gastrointestinal tumors, colon cancer and pancreatic cancer [29,30].

People with autoimmune gluten intolerance may have other co-existing autoimmune diseases such as type 1 diabetes, hyperthyroidism, vitiligo, primary biliary cirrhosis, rheumatoid arthritis [31], iron deficiency anemia, osteopenia and osteoporosis, hyposplenism or IgA nephropathy [32].

Despite the many negative effects of gluten consumption, its introduction to the infant diet does not cause adverse effects in their psychomotor development [33]. Gliadin, on the other hand, contributes to the enhanced action of the human immune system through the influence on monocytes and their cytokine production [34].

Table 1: The overall cognitive effect of gluten.

The review of many scientific publications has expanded our knowledge on this subject (Table 1), and not only medical knowledge, but also of agricultural genetics, which in the last 50 years has transformed traditional wheat into a hybrid productprofitable, robust and efficient, but little related to the original. One should remember that biological and genetic modifications of wheat were introduced with good intentions. At the turn of the 1960s, there was a fear of world overcrowding and hunger in in the West. It was decided to increase cereal cultivations; the US and other highly developed countries began to invest huge amounts in research aimed at improving plants and increasing yields. Breeding programs existing to this day, based on wheat genetics and biotechnology, have achieved success, and currently we have highly fertile wheat with good grain quality parameters (group A, B). A wide breeding program taking into account all directions, based on global gene resources, provides annually new, better forms of common wheat.

Read More About this Article: https://biomedgrid.com/fulltext/volume4/wheat-gluten-desirable-or-dangerous-genes.000794.php

For more about: Journals on Biomedical Science :Biomed Grid | Current Issue

[lauramalchowblog]

3 Common Skin Conditions and What to Do about Them

“Love the skin you’re in,” so the saying goes. Sometimes that’s easier said than done. Skin conditions, ranging from mildly irritating to painfully debilitating, are ubiquitous nowadays. Even mild-to-moderate symptoms can take a serious physical and emotional toll.

I started thinking about skin the other day after a bout of nostalgia had me revisiting old reader success stories. Going through the archives, I was reminded how many readers reported that their acne, psoriasis, eczema, and other skin conditions were “miraculously” resolved after going Primal.

I’m not surprised. I’ve always believed that there is a deep connection between skin health, gut health, and inflammation. The Primal Blueprint is designed to support a diverse, well-balanced microbiome, reduce chronic inflammation, and provide epigenetic signals that optimize health. It makes sense that clearer skin would be one of the benefits.

As I perused the success stories, it occurred to me that it’s been a while since we talked about skin issues here. Today I’m going to cover three of the most common, along with some alternative (non-pharmaceutical) approaches to addressing them. Don’t get me wrong. I’m not judging anyone for opting for pharmaceutical options. However, many conventional treatments—antibiotics, oral steroids, hormonal birth control pills, and isotretinoin (sold with brand name Accutane)—have serious, sometimes downright scary, side effects.

Given that, I know many of my readers are interested in diet and lifestyle interventions that might help. They won’t fix all your skin issues, but they’re bound to improve some aspects of your life, even if your skin doesn’t clear up completely.

Acne

Acne is widespread among adolescents and adults. The most common form of acne is acne vulgaris. You’re undoubtedly familiar with the characteristic whiteheads and blackheads usually found on the face, chest, back, and shoulders. Cystic and nodular acne are severe types of acne vulgaris involve large, deep, painful blemishes that take longer to heal.

Acne doesn’t have a single root cause. Sebum (oil) production, pore blockage, bacteria (Propionibacterium acnes), and inflammation each contribute. Androgens increase sebum production, and hormonal changes due to puberty, menstruation, pregnancy, PCOS, or menopause often lead to outbreaks.

As common as these skin issues are today, they are not an inevitable part of the human condition. Grandfather of the ancestral health movement Loren Cordain asserts that acne is basically unheard of in traditional-living societies.1 This strongly suggests that modern lifestyle factors that affect epigenetics, inflammation, and hormones, underlie much of what we see today.

What to Do About Your Acne

Because acne is multifactorial, there is no single magic pill for acne. Sufferers may try a variety of topical, pharmaceutical, and lifestyle interventions before (hopefully) finding the key that works for them. It can take trial and error, luck, and time. There are also a lot of old wives’ tales that send people down all sorts of rabbit holes looking for answers. Many fall into the category of “can’t hurt, might help.” A few are actually backed by science:

Diet

Many supposed dietary causes of acne aren’t substantiated by research. (Chocolate doesn’t seem to cause acne, thankfully.) However, the American Academy of Dermotology (AAD) agrees that two factors matter:2

Glycemic load

Both observational and experimental studies link greater intake of high-glycemic carbohydrates to more frequent and more severe acne symptoms. For some people, acne is significantly improved simply by lowering the glycemic load of their diet.

High-glycemic load diets probably promote acne through several metabolic pathways, including by stimulating insulinlike growth factor 1 (IGF-1) and androgen.3 4 Acne sufferers would do well to moderate their carb intake, especially high-glycemic carbs. The good news is that if you’re already eating a Primal-aligned diet, you’ve probably greatly cut down your glycemic load by removing grains and added sugars, as well as legumes. Fruit can also carry a heft wallop.

Dairy

The AAD recommends that acne sufferers limit dairy intake.5 The available data is observational, so take it for what it’s worth. Still, a recent meta-analysis found that folks who drink more milk are more prone to acne. There was no significant relationship for cheese or yogurt consumption.6 This jibes with tons of anecdotal evidence from people who report significant relief from acne symptoms when they cut out dairy.

What about other food sensitivities?

I can’t tell you how many readers have confided they struggled for years, even decades, with acne before switching to a Primal diet and finally getting relief. Many of them have traced their problem back to gluten. Some are particularly affected by dairy, others by soy. Occasionally, random food sensitivities are the issue.

Despite the preponderance of anecdotal evidence, there is a glaring lack of scientific studies on food sensitivities and acne, so the link remains somewhat controversial. No matter. This is one of those cases where proof is in the pudding as far as I’m concerned.

If you are suffering from stubborn acne, consider what foods may be triggering for you. Start with the usual suspects. Track your symptoms and see if you can spot any patterns. When you identify likely culprits, try eliminating them for a few weeks and see what happens with your skin.

What If Dietary Changes Alone Don’t Solve My Acne?

First things first, look at your gut health. There is a strong gut-skin connection.7 Addressing underlying gut health issues, as well as supplementing with probiotics (Lactobacillus and Bifidobacteria), can reduce acne.8 You have nothing to lose by adding sauerkraut or kimchi to your meals. If you’re not sensitive to dairy, try kefir, one of my favorite sources of probiotics. You can even try doing a yogurt mask since topical probiotic treatments could be beneficial.

Supplementing with certain nutrients might help, too. There is limited evidence in support of zinc,9 vitamin B3,10 and fish oil supplements.11

Finally, work on your skin’s surface. Some people swear by using coconut oil on their face, but it can be aggravating for others. Try topical applications of manuka honey, tea tree oil (diluted), witch hazel, green tea extract, or apple cider vinegar. None of these is likely to be a slam dunk on its own, but use them alongside dietary changes and wise supplementation, and you might just arrive at a winning combo.

Eczema

As with acne, there are several forms of eczema. The most common is atopic dermatitis. Eczema is characterized by dry, itchy, swollen rashes that appear most often on the face, neck, elbows, and knees. People of any age can develop eczema, but it’s more common in babies and children. Up to 20 percent of children and 5 percent of adults are afflicted.12 Doctors aren’t sure what causes it. Rashes seem to be triggered by an immune system reaction, but it’s not clear why. Specific triggers differ from person to person.

Because the root causes are unknown, finding relief can also be difficult and frustrating. Patients are advised to keep affected areas moisturized, avoid detergents and soaps that might irritate the skin, opt for cotton clothing, and take baths with oatmeal or vinegar. Doctors may prescribe topical steroids or other creams or, in extreme cases, immunosuppressing drugs.

Other Ways to Address Eczema

Probiotics?

Studies of infants and young children have found that eczema sufferers have, on average, less microbial diversity in their guts.13 14 Probiotic supplementation, especially with strains of Lactobacillus, may reduce the risk of developing eczema15 and relieve eczema symptoms.16 A 2012 meta-analysis also concluded that when pregnant women supplement with probiotics, their babies have a significantly reduced risk of developing eczema.17

However, a recent Cochrane review concluded that there is insufficient evidence to recommend probiotics as an effective eczema treatment.18 There are so many other benefits of supporting a healthy microbiome that it doesn’t hurt to try probiotics, though.

Coconut oil

Thanks to its antimicrobial and anti-inflammatory properties, coconut oil applied topically to eczema rashes may provide some relief.19 If nothing else, it will moisturize dry skin and smell great.

Acupressure, acupuncture, and massage

A few small studies have found that acupressure 20, acupuncture 21, and massage[/ref]https://pubmed.ncbi.nlm.nih.gov/9796594/[/ref] may provide some relief. In addition to physiologic benefits, these treatments may reduce stress, which is known to trigger flare-ups.

Get outside

Your doctor may use phototherapy treatments, but you can also reap the benefits of ultraviolet light simply by getting out in the sun.22 Ultraviolet radiation triggers the release of nitric oxide, which in turn activates T cells that modulate the overactive immune response.23

Dermatologists caution that sun exposure is not recommended for severe cases, and it exacerbates symptoms for some people. Be careful not to overdo it. Besides the risk of burning, getting too hot and sweaty leads to itching and discomfort.

Psoriasis

With plaque psoriasis—the most common form—red, scaly, often itchy or painful patches rise on the scalp, knees, elbows, lower back, or really anywhere on the body. Other types of psoriasis cause red lesions in folds such as the armpit, small dots, or blisters. Psoriasis can also affect the fingernails and toenails.

Psoriasis shares a lot in common with eczema. Doctors don’t know exactly what causes it, but it has a genetic component and is classified as an autoimmune disease. Symptoms come and go, and different people may have different triggers. Doctors usually treat psoriasis with topical creams, but they may also prescribe oral medications to try to get at it systemically.

Unlike eczema, though, psoriasis is more common in adults than children. Up to 30 percent of people with psoriasis develop a related condition called psoriatic arthritis. Because it is associated with systemic inflammation, psoriasis puts you at greater risk for other chronic health conditions such as metabolic syndrome and 24 cardiovascular disease.25

Treating Psoriasis with Diet

Gluten sensitivity is probably more common among psoriasis sufferers than in the general population. I think gluten sensitivity is more common than is generally recognized, but that aside, I’d strongly suggest that anyone with psoriasis try eliminating gluten completely for a period of time.

Calorie-restricted diets also yield significant improvements in symptom severity for obese individuals, but it’s not clear whether that is due to the calorie restriction per se, weight loss, or something else.26 27

If you have psoriasis, you should also limit your alcohol intake. A growing body of evidence suggests that alcohol can worsen symptoms. Psoriasis also comes with a higher risk of liver disease, making excess alcohol consumption potentially more dangerous.28

Supplements

Many psoriasis patients try supplementing with fish oil, selenium, and vitamins D and B12, but there is only mixed evidence that they are actually effective.29 (Vitamin D is commonly applied in topical creams.) They may be helpful for some people, though.

There is also a lot of interest in curcumin, a compound found in turmeric. A number of small clinical trials have yielded some success, but it’s still early. A recent meta-analysis concluded that the available data do not support using curcumin topically, but taking it as an oral supplement shows promise.30

Stress reduction

Stress leads to psoriasis flare-ups.31 Therefore, anything you do to moderate stress may help prevent or manage symptoms. Meditation and guided imagery seem to work.32 Or, treat yourself to an at-home spa day. Start with an Epsom salt or oatmeal bath, then apply some topical treatments using stuff you already have in the house. The National Psoriasis Association recommends using aloe vera, apple cider vinegar, and tea tree oil topically, as well as mahonia (Oregon grape) cream (which you probably don’t have lying around).33

Sunlight

Ultraviolet light, especially UVB, can help with psoriasis symptoms. Certain topical treatments make you more susceptible to sunburn, so check out any medications you’re using.

Acupuncture

A 2017 review of studies involving more than 1,000 participants concluded that acupuncture and acupressure can help with psoriasis.34

General takeaways

Skin disorders are complex. The remedies I mentioned here are not the only ones you might try. Severe or prolonged cases may respond best to a combination of treatments, including medications.

No matter what your specific challenge, the following are always good practice:

Support a healthy gut microbiome through the usual means.

Eat a nutrient-rich diet. Most vitamins and minerals directly and indirectly affect skin health. Vitamins A, D, and E probably get the most attention, but they are all important.

Avoid harsh cleansers and products that might irritate your skin. I have a few posts about Primal skincare, but the most Primal skincare “product” is just plain (clean, filtered) water.

Avoid foods that promote inflammation. If you suspect that food sensitivities make your skin problems worse, simple elimination experiments can provide answers. For skin issues, it’s not generally necessary to undertake a complete elimination diet along the lines of the autoimmune protocol (AIP) or low-FODMAP. However, if you have other symptoms that suggest serious gut health impairment, your practitioner may recommend that you do eliminate a wider swath of foods for a while.

Finally, avoid touching your face as much as possible. That’s just a good idea anyway.

I know I just scratched the tip of the iceberg here. Tell me about your personal successes and challenges. What’s your secret for healthy skin? Maybe your advice can help someone else.

(function($) { $("#df0eOYy").load("https://www.marksdailyapple.com/wp-admin/admin-ajax.php?action=dfads_ajax_load_ads&groups=674&limit=1&orderby=random&order=ASC&container_id=&container_html=none&container_class=&ad_html=div&ad_class=&callback_function=&return_javascript=0&_block_id=df0eOYy" ); })( jQuery );

References

https://pubmed.ncbi.nlm.nih.gov/12472346/

https://pubmed.ncbi.nlm.nih.gov/26897386/

https://pubmed.ncbi.nlm.nih.gov/12472346/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769025/

https://pubmed.ncbi.nlm.nih.gov/26897386/

https://www.sciencedirect.com/science/article/abs/pii/S0261561418301663

https://www.wjgnet.com/2218-6190/full/v6/i4/52.htm

https://www.ncbi.nlm.nih.gov/pubmed/23886975

https://www.ncbi.nlm.nih.gov/pubmed/20666829

https://pubmed.ncbi.nlm.nih.gov/17147561/

https://pubmed.ncbi.nlm.nih.gov/24553997/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516982/

https://pubmed.ncbi.nlm.nih.gov/22831283/

https://pubmed.ncbi.nlm.nih.gov/30860574/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516982/

https://www.ncbi.nlm.nih.gov/pubmed/11069570

https://www.ncbi.nlm.nih.gov/books/NBK91608/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517242/

https://pubmed.ncbi.nlm.nih.gov/24320105/

https://pubmed.ncbi.nlm.nih.gov/22207450/

https://pubmed.ncbi.nlm.nih.gov/30477869/

https://www.ncbi.nlm.nih.gov/pubmed/22813359

https://pubmed.ncbi.nlm.nih.gov/28601680/

https://www.ncbi.nlm.nih.gov/pubmed/29241748

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666891/

https://www.ncbi.nlm.nih.gov/pubmed/31309536

https://pubmed.ncbi.nlm.nih.gov/29926091/

https://pubmed.ncbi.nlm.nih.gov/22004481/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134971/

https://www.ncbi.nlm.nih.gov/pubmed/30193251

https://pubmed.ncbi.nlm.nih.gov/8513683/

https://www.ncbi.nlm.nih.gov/pubmed/30193251

https://www.psoriasis.org/treating-psoriasis/complementary-and-alternative/herbal-remedies

https://pubmed.ncbi.nlm.nih.gov/28628749/

The post 3 Common Skin Conditions and What to Do about Them appeared first on Mark's Daily Apple.

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[jesseneufeld]

3 Common Skin Conditions and What to Do about Them

“Love the skin you’re in,” so the saying goes. Sometimes that’s easier said than done. Skin conditions, ranging from mildly irritating to painfully debilitating, are ubiquitous nowadays. Even mild-to-moderate symptoms can take a serious physical and emotional toll.

I started thinking about skin the other day after a bout of nostalgia had me revisiting old reader success stories. Going through the archives, I was reminded how many readers reported that their acne, psoriasis, eczema, and other skin conditions were “miraculously” resolved after going Primal.

I’m not surprised. I’ve always believed that there is a deep connection between skin health, gut health, and inflammation. The Primal Blueprint is designed to support a diverse, well-balanced microbiome, reduce chronic inflammation, and provide epigenetic signals that optimize health. It makes sense that clearer skin would be one of the benefits.

As I perused the success stories, it occurred to me that it’s been a while since we talked about skin issues here. Today I’m going to cover three of the most common, along with some alternative (non-pharmaceutical) approaches to approaching them. Don’t get me wrong. I’m not judging anyone for opting for pharmaceutical options. However, many conventional treatments—antibiotics, oral steroids, hormonal birth control pills, and isotretinoin (sold with brand name Accutane)—have serious, sometimes downright scary, side effects.

Given that, I know many of my readers are interested in diet and lifestyle interventions that might help. They won’t fix all your skin issues, but they’re bound to improve some aspects of your life, even if your skin doesn’t clear up completely.

Acne

Acne is widespread among adolescents and adults. The most common form of acne is acne vulgaris. You’re undoubtedly familiar with the characteristic whiteheads and blackheads usually found on the face, chest, back, and shoulders. Cystic and nodular acne are severe types of acne vulgaris involve large, deep, painful blemishes that take longer to heal.

Acne doesn’t have a single root cause. Sebum (oil) production, pore blockage, bacteria (Propionibacterium acnes), and inflammation each contribute. Androgens increase sebum production, and hormonal changes due to puberty, menstruation, pregnancy, PCOS, or menopause often lead to outbreaks.

As common as these skin issues are today, they are not an inevitable part of the human condition. Grandfather of the ancestral health movement Loren Cordain asserts that acne is basically unheard of in traditional-living societies.1 This strongly suggests that modern lifestyle factors that affect epigenetics, inflammation, and hormones, underlie much of what we see today.

What to Do About Your Acne

Because acne is multifactorial, there is no single magic pill for acne. Sufferers may try a variety of topical, pharmaceutical, and lifestyle interventions before (hopefully) finding the key that works for them. It can take trial and error, luck, and time. There are also a lot of old wives’ tales that send people down all sorts of rabbit holes looking for answers. Many fall into the category of “can’t hurt, might help.” A few are actually backed by science:

Diet

Many supposed dietary causes of acne aren’t substantiated by research. (Chocolate doesn’t seem to cause acne, thankfully.) However, the American Academy of Dermotology (AAD) agrees that two factors matter:2

Glycemic load

Both observational and experimental studies link greater intake of high-glycemic carbohydrates to more frequent and more severe acne symptoms. For some people, acne is significantly improved simply by lowering the glycemic load of their diet.

High-glycemic load diets probably promote acne through several metabolic pathways, including by stimulating insulinlike growth factor 1 (IGF-1) and androgen.3 4 Acne sufferers would do well to moderate their carb intake, especially high-glycemic carbs. The good news is that if you’re already eating a Primal-aligned diet, you’ve probably greatly cut down your glycemic load by removing grains and added sugars, as well as legumes. Fruit can also carry a heft wallop.

Dairy

The AAD recommends that acne sufferers limit dairy intake.5 The available data is observational, so take it for what it’s worth. Still, a recent meta-analysis found that folks who drink more milk are more prone to acne. There was no significant relationship for cheese or yogurt consumption.6 This jibes with tons of anecdotal evidence from people who report significant relief from acne symptoms when they cut out dairy.

What about other food sensitivities?

I can’t tell you how many readers have confided they struggled for years, even decades, with acne before switching to a Primal diet and finally getting relief. Many of them have traced their problem back to gluten. Some are particularly affected by dairy, others by soy. Occasionally, random food sensitivities are the issue.

Despite the preponderance of anecdotal evidence, there is a glaring lack of scientific studies on food sensitivities and acne, so the link remains somewhat controversial. No matter. This is one of those cases where proof is in the pudding as far as I’m concerned.

If you are suffering from stubborn acne, consider what foods may be triggering for you. Start with the usual suspects. Track your symptoms and see if you can spot any patterns. When you identify likely culprits, try eliminating them for a few weeks and see what happens with your skin.

What If Dietary Changes Alone Don’t Solve My Acne?

First things first, look at your gut health. There is a strong gut-skin connection.7 Addressing underlying gut health issues, as well as supplementing with probiotics (Lactobacillus and Bifidobacteria), can reduce acne.8 You have nothing to lose by adding sauerkraut or kimchi to your meals. If you’re not sensitive to dairy, try kefir, one of my favorite sources of probiotics. You can even try doing a yogurt mask since topical probiotic treatments could be beneficial.

Supplementing with certain nutrients might help, too. There is limited evidence in support of zinc,9 vitamin B3,10 and fish oil supplements.11

Finally, work on your skin’s surface. Some people swear by using coconut oil on their face, but it can be aggravating for others. Try topical applications of manuka honey, tea tree oil (diluted), witch hazel, green tea extract, or apple cider vinegar. None of these is likely to be a slam dunk on its own, but use them alongside dietary changes and wise supplementation, and you might just arrive at a winning combo.

Eczema

As with acne, there are several forms of eczema. The most common is atopic dermatitis. Eczema is characterized by dry, itchy, swollen rashes that appear most often on the face, neck, elbows, and knees. People of any age can develop eczema, but it’s more common in babies and children. Up to 20 percent of children and 5 percent of adults are afflicted.12 Doctors aren’t sure what causes it. Rashes seem to be triggered by an immune system reaction, but it’s not clear why. Specific triggers differ from person to person.

Because the root causes are unknown, finding relief can also be difficult and frustrating. Patients are advised to keep affected areas moisturized, avoid detergents and soaps that might irritate the skin, opt for cotton clothing, and take baths with oatmeal or vinegar. Doctors may prescribe topical steroids or other creams or, in extreme cases, immunosuppressing drugs.

Other Ways to Address Eczema

Probiotics?

Studies of infants and young children have found that eczema sufferers have, on average, less microbial diversity in their guts.13 14 Probiotic supplementation, especially with strains of Lactobacillus, may reduce the risk of developing eczema15 and relieve eczema symptoms.16 A 2012 meta-analysis also concluded that when pregnant women supplement with probiotics, their babies have a significantly reduced risk of developing eczema.17

However, a recent Cochrane review concluded that there is insufficient evidence to recommend probiotics as an effective eczema treatment.18 There are so many other benefits of supporting a healthy microbiome that it doesn’t hurt to try probiotics, though.

Coconut oil

Thanks to its antimicrobial and anti-inflammatory properties, coconut oil applied topically to eczema rashes may provide some relief.19 If nothing else, it will moisturize dry skin and smell great.

Acupressure, acupuncture, and massage

A few small studies have found that acupressure 20, acupuncture 21, and massage[/ref]https://pubmed.ncbi.nlm.nih.gov/9796594/[/ref] may provide some relief. In addition to physiologic benefits, these treatments may reduce stress, which is known to trigger flare-ups.

Get outside

Your doctor may use phototherapy treatments, but you can also reap the benefits of ultraviolet light simply by getting out in the sun.22 Ultraviolet radiation triggers the release of nitric oxide, which in turn activates T cells that modulate the overactive immune response.23

Dermatologists caution that sun exposure is not recommended for severe cases, and it exacerbates symptoms for some people. Be careful not to overdo it. Besides the risk of burning, getting too hot and sweaty leads to itching and discomfort.

Psoriasis

With plaque psoriasis—the most common form—red, scaly, often itchy or painful patches rise on the scalp, knees, elbows, lower back, or really anywhere on the body. Other types of psoriasis cause red lesions in folds such as the armpit, small dots, or blisters. Psoriasis can also affect the fingernails and toenails.

Psoriasis shares a lot in common with eczema. Doctors don’t know exactly what causes it, but it has a genetic component and is classified as an autoimmune disease. Symptoms come and go, and different people may have different triggers. Doctors usually treat psoriasis with topical creams, but they may also prescribe oral medications to try to get at it systemically.

Unlike eczema, though, psoriasis is more common in adults than children. Up to 30 percent of people with psoriasis develop a related condition called psoriatic arthritis. Because it is associated with systemic inflammation, psoriasis puts you at greater risk for other chronic health conditions such as metabolic syndrome and 24 cardiovascular disease.25

Treating Psoriasis with Diet

Gluten sensitivity is probably more common among psoriasis sufferers than in the general population. I think gluten sensitivity is more common than is generally recognized, but that aside, I’d strongly suggest that anyone with psoriasis try eliminating gluten completely for a period of time.

Calorie-restricted diets also yield significant improvements in symptom severity for obese individuals, but it’s not clear whether that is due to the calorie restriction per se, weight loss, or something else.26 27

If you have psoriasis, you should also limit your alcohol intake. A growing body of evidence suggests that alcohol can worsen symptoms. Psoriasis also comes with a higher risk of liver disease, making excess alcohol consumption potentially more dangerous.28

Supplements

Many psoriasis patients try supplementing with fish oil, selenium, and vitamins D and B12, but there is only mixed evidence that they are actually effective.29 (Vitamin D is commonly applied in topical creams.) They may be helpful for some people, though.

There is also a lot of interest in curcumin, a compound found in turmeric. A number of small clinical trials have yielded some success, but it’s still early. A recent meta-analysis concluded that the available data do not support using curcumin topically, but taking it as an oral supplement shows promise.30

Stress reduction

Stress leads to psoriasis flare-ups.31 Therefore, anything you do to moderate stress may help prevent or manage symptoms. Meditation and guided imagery seem to work.32 Or, treat yourself to an at-home spa day. Start with an Epsom salt or oatmeal bath, then apply some topical treatments using stuff you already have in the house. The National Psoriasis Association recommends using aloe vera, apple cider vinegar, and tea tree oil topically, as well as mahonia (Oregon grape) cream (which you probably don’t have lying around).33

Sunlight

Ultraviolet light, especially UVB, can help with psoriasis symptoms. Certain topical treatments make you more susceptible to sunburn, so check out any medications you’re using.

Acupuncture

A 2017 review of studies involving more than 1,000 participants concluded that acupuncture and acupressure can help with psoriasis.34

General takeaways

Skin disorders are complex. The remedies I mentioned here are not the only ones you might try. Severe or prolonged cases may respond best to a combination of treatments, including medications.

No matter what your specific challenge, the following are always good practice:

Support a healthy gut microbiome through the usual means.

Eat a nutrient-rich diet. Most vitamins and minerals directly and indirectly affect skin health. Vitamins A, D, and E probably get the most attention, but they are all important.

Avoid harsh cleansers and products that might irritate your skin. I have a few posts about Primal skincare, but the most Primal skincare “product” is just plain (clean, filtered) water.

Avoid foods that promote inflammation. If you suspect that food sensitivities make your skin problems worse, simple elimination experiments can provide answers. For skin issues, it’s not generally necessary to undertake a complete elimination diet along the lines of the autoimmune protocol (AIP) or low-FODMAP. However, if you have other symptoms that suggest serious gut health impairment, your practitioner may recommend that you do eliminate a wider swath of foods for a while.

Finally, avoid touching your face as much as possible. That’s just a good idea anyway.

I know I just scratched the tip of the iceberg here. Tell me about your personal successes and challenges. What’s your secret for healthy skin? Maybe your advice can help someone else.

(function($) { $("#dfgv4T2").load("https://www.marksdailyapple.com/wp-admin/admin-ajax.php?action=dfads_ajax_load_ads&groups=674&limit=1&orderby=random&order=ASC&container_id=&container_html=none&container_class=&ad_html=div&ad_class=&callback_function=&return_javascript=0&_block_id=dfgv4T2" ); })( jQuery );

References

https://pubmed.ncbi.nlm.nih.gov/12472346/

https://pubmed.ncbi.nlm.nih.gov/26897386/

https://pubmed.ncbi.nlm.nih.gov/12472346/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769025/

https://pubmed.ncbi.nlm.nih.gov/26897386/

https://www.sciencedirect.com/science/article/abs/pii/S0261561418301663

https://www.wjgnet.com/2218-6190/full/v6/i4/52.htm

https://www.ncbi.nlm.nih.gov/pubmed/23886975

https://www.ncbi.nlm.nih.gov/pubmed/20666829

https://pubmed.ncbi.nlm.nih.gov/17147561/

https://pubmed.ncbi.nlm.nih.gov/24553997/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516982/

https://pubmed.ncbi.nlm.nih.gov/22831283/

https://pubmed.ncbi.nlm.nih.gov/30860574/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516982/

https://www.ncbi.nlm.nih.gov/pubmed/11069570

https://www.ncbi.nlm.nih.gov/books/NBK91608/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517242/

https://pubmed.ncbi.nlm.nih.gov/24320105/

https://pubmed.ncbi.nlm.nih.gov/22207450/

https://pubmed.ncbi.nlm.nih.gov/30477869/

https://www.ncbi.nlm.nih.gov/pubmed/22813359

https://pubmed.ncbi.nlm.nih.gov/28601680/

https://www.ncbi.nlm.nih.gov/pubmed/29241748

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666891/

https://www.ncbi.nlm.nih.gov/pubmed/31309536

https://pubmed.ncbi.nlm.nih.gov/29926091/

https://pubmed.ncbi.nlm.nih.gov/22004481/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134971/

https://www.ncbi.nlm.nih.gov/pubmed/30193251

https://pubmed.ncbi.nlm.nih.gov/8513683/

https://www.ncbi.nlm.nih.gov/pubmed/30193251

https://www.psoriasis.org/treating-psoriasis/complementary-and-alternative/herbal-remedies

https://pubmed.ncbi.nlm.nih.gov/28628749/

The post 3 Common Skin Conditions and What to Do about Them appeared first on Mark's Daily Apple.

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[eczemang-blog]

 Acne Rosacea Treatment - Best Recommendations

The Acne Rosacea Treatment is almost equivalent to our previous treatment recommendations. You can get the better options here on how you can possibly get yourself treated at ease. The acne rosacea is a very dangerous infection of the skin. This skin infection requires a better acne rosacea treatment and that is what we will be talking about on this very thread. Perhaps you may want to know what Acne Rosacea really is. Yeah! knowing what it is really matters on this very contest since it engineers the main anchor of this article. For we to go further to the acne rosacea treatment, let's dig this first. Because of this un-clarified matter, you may likely not comprehend or grasp anything we would be talking about here. So this apparently lead me to ask "what is acne rosacea? this question should be anchored before we talk about  Acne Rosacea Treatment.

What Is Acne Rosacea?

Now let's candidly talk about what a rosacea mean. But before that, I would want you to comprehend this matter. This rosacea seems to be similar to psoriasis but not same. So take your time to understand what makes them similar and why they differ from each other. And always remember that we are here to secure a better acne rosacea treatment. Great experts and mentors have been able to give us a specific details on this context and on the acne rosacea treatment too. Meanwhile, rosacea is simply a common chronic. This rosacea could sometimes be very progressive and dermatosis. Meanwhile rosacea can occur in adults of any ethnicity, and adversely affects patients' quality of life. Also the rosacea acne is characterized in combination by central facial erythema, symmetric flushing, stinging sensation, inflammatory lesions (papules and pustules), telangiectasias, and phymatous changes (tissue hyperplasia and nodules). The condition can be effectively controlled with therapy tailored to the specific subtype of rosacea that is affecting the patient. Topical metronidazole, sulfacetamide/sulfur, and azelaic acid are generally effective for patients with mild rosacea. Again for moderate papulopustular rosacea, combination therapy with oral tetracyclines and topical agents is the first-line choice. Acne Rosacea Treatment with a topical agent, such as metronidazole, may help maintain remission. Patients with ocular involvement may benefit from long-term oral antibiotics and metronidazole gel. Adittionally, you being referred to asubspecialist is necessary for patients who have ocular rosacea with ophthalmic complications, severe or recalcitrant rosacea, or phymatous changes. Brief Introduction To Acne Rosacea From researchers record, the rosacea has affected over 14 million people in the United States. You see the reason why we've prescribed an acne rosacea treatment. These treatments will help reduce, or even terminate the existence of this very skin problem, from the united states. It is more common in white persons but can occur in persons of other ethnicities. Rosacea is somewhat more likely to occur in women. It generally emerges when patients are in their 30s, although it can develop in younger age groups. The influence of heredity on the development of rosacea has not been well studied. However, one survey suggests that first- and second-degree relatives of patients with rosacea have a higher rate of rosacea, and persons of Irish, English, or German ancestry are more likely to develop the disease. Although this evidence is weak, it supports epidemiologic patterns that are anecdotally noted in the literature. The differential diagnosis of rosacea includes acne vulgaris, systemic lupus erythematosus, polymyositis, sarcoidosis, photodermatitis, drug eruptions (particularly from iodides and bromides), granulomas of the skin, and perioral dermatitis. The differential diagnosis of ocular rosacea may include staphylococcal and seborrheic blepharokeratoconjunctivitis, and sebaceous gland carcinoma.  Acne Rosacea symptoms In addition to all these, rosacea is a very common skin condition with characteristic symptoms and signs. These signs and symptoms includes the following; Symmetric flushing Stinging sensation Inflammatory lesions (papules and pustules) Telangiectasias on the face. Now in most cases, this may cause inflammation of the eyes and eyelids. Whereas in most patients, the central area of the face is affected so terribly. The parts of the face which could be affected is the nose, the chin, the perioral areas and the forehead.Also phymatous changes include thickened skin and large pores. Moreover, clinical findings represent a spectrum of disease with one or several predominating characteristics, including a pattern of exacerbations and relative inactivity. Also, the National Rosacea Society classifies rosacea into four sub-types. These are listed below; Papulopustular Ocular Erythematotelangiectatic and Phymatous Those are the various sub-types of this very rosacea and they shouldn't be neglected, Meanwhile, these sub-types are classified by severity based on the number of papules/pustules and plaques. Acne Rosacea Treatment There are several and numerous acne rosacea treament we will taking about here. The aim of unveiling these treatments is to make you live better and free from rosacea and other skin diseases, Topical Therapy The topical therapy is one of the best of it's kind. When you neglect this method, it simply means that you don't want to embrace quick recovery from rosacea. When we talk about acne rosacea treatment; let's not forget this topica therapy. The topical therapy rocks! Topical regimens are first-line therapies for mild papulopustular rosacea because there is less risk of adverse events, drug interactions, and antibiotic resistance. The severity of the patient's presentation helps guide the decision to initiate topical therapy alone or in combination with systemic therapy. Systemic therapy should be withdrawn when adequate response occurs Yeah! take that very method to get acne rosacea treatment and be happy once again. Drug Therapy I hardly see people talk about this very acne rosacea treatment method. Perhaps they thought that this method isn't effective or wouldn't yield a better result. But nevertheless, the drug therapy is actually one of the best. On a serious note, when we talk about acne rosacea treatment, I think we shouldn't neglect this simple method because it really matters a lot. Drug therapy should be based on rosacea classification, severity, and response to previous treatment regimens. As for acne rosacea treatment, the following may be recommended to reduce rosacea flares: Use of emollient, noncomedogenic moisturizers and mild, fragrance-free, soap-free cleansers that have a nonalkaline or neutral pH level. Avoidance of astringents and other skin care products containing alcohol, menthol, eucalyptus oil, clove oil, peppermint, witch hazel, or sodium lauryl sulfate. This will help as it is one of the acne rosacea treatment. Use of broad-spectrum sunscreen containing either zinc oxide or titanium dioxide, and wide-brimmed hats Meanwhile, the initial drug therapy for mild rosacea should include appropriate topical regimens, such as antibiotics, immunomodulators, or retinoids. First-line topical regimens (e.g., metronidazole , azelaic acid , sulfacetamide/sulfur) should be applied once or twice daily. Yeah! take this drug therapy method to get acne rosacea treatment and be happy once again. Nonpharmacologic Therapy The nonpharmacologic therapy is one of the best in the area of acne rosacea treatment. The initial therapeutic approach for rosacea, especially the erythematotelangiectatic and papulopustular subtypes, is avoidance of known triggers or exacerbating factors when possible. These factors may be specific to individual patients. The particular acne rosacea treatment rocks, don't neglect it. Did you find this content very resourceful? of do you have any question based on acne rosacea treatment? or any suggestion to render on the acne rosacea treatment? Just feel free to send us your feedback using the comment box below, thanks. Read the full article