#churg strauss syndrome

[does-truth-matter]

The CDC has quietly changed who should AVOID the MMR vaccine.

https://www.cdc.gov/vaccines/vpd/mmr/public/index.html

They now state that ANYONE that “Has a parent, brother or sister with a history of immune system problems” should AVOID THE MMR VACCINE!

What exactly is an 'immune system problem?" Every autoimmune disorder.

* Achalasia

* Addison’s disease

* Adult Still's disease

* Agammaglobulinemia

* Alopecia areata

* Amyloidosis

* Amyotrophic lateral sclerosis (Lou Gehrigs)

* Ankylosing spondylitis

* Anti-GBM/Anti-TBM nephritis

* Antiphospholipid syndrome

* Autoimmune angioedema

* Autoimmune dysautonomia

* Autoimmune encephalomyelitis

* Autoimmune hepatitis

* Autoimmune inner ear disease (AIED)

* Autoimmune myocarditis

* Autoimmune oophoritis

* Autoimmune orchitis

* Autoimmune pancreatitis

* Autoimmune retinopathy

* Autoimmune urticaria

* Axonal & neuronal neuropathy (AMAN)

* Baló disease

* Behcet’s disease

* Benign mucosal pemphigoid

* Bullous pemphigoid

* Castleman disease (CD)

* Celiac disease

* Chagas disease

* Chronic inflammatory demyelinating polyneuropathy (CIDP)

* Chronic recurrent multifocal osteomyelitis (CRMO)

* Churg-Strauss Syndrome (CSS) or Eosinophilic Granulomatosis (EGPA)

* Cicatricial pemphigoid

* Cogan’s syndrome

* Cold agglutinin disease

* Congenital heart block

* Coxsackie myocarditis

* CREST syndrome

* Crohn’s disease

* Dermatitis herpetiformis

* Dermatomyositis

* Devic’s disease (neuromyelitis optica)

* Discoid lupus

* Dressler’s syndrome

* Endometriosis

* Eosinophilic esophagitis (EoE)

* Eosinophilic fasciitis

* Erythema nodosum

* Essential mixed cryoglobulinemia

* Evans syndrome

* Fibromyalgia

* Fibrosing alveolitis

* Giant cell arteritis (temporal arteritis)

* Giant cell myocarditis

* Glomerulonephritis

* Goodpasture’s syndrome

* Granulomatosis with Polyangiitis

* Graves’ disease

* Guillain-Barre syndrome

* Hashimoto’s thyroiditis

* Hemolytic anemia

* Henoch-Schonlein purpura (HSP)

* Herpes gestationis or pemphigoid gestationis (PG)

* Hidradenitis Suppurativa (HS) (Acne Inversa)

* Hypogammalglobulinemia

* IgA Nephropathy

* IgG4-related sclerosing disease

* Immune thrombocytopenic purpura (ITP)

* Inclusion body myositis (IBM)

* Interstitial cystitis (IC)

* Juvenile arthritis

* Juvenile diabetes (Type 1 diabetes)

* Juvenile myositis (JM)

* Kawasaki disease

* Lambert-Eaton syndrome

* Leukocytoclastic vasculitis

* Lichen planus

* Lichen sclerosus

* Ligneous conjunctivitis

* Linear IgA disease (LAD)

* Lupus

* Lyme disease chronic

* Meniere’s disease

* Microscopic polyangiitis (MPA)

* Mixed connective tissue disease (MCTD)

* Mooren’s ulcer

* Mucha-Habermann disease

* Multifocal Motor Neuropathy (MMN) or MMNCB

* Multiple sclerosis

* Myasthenia gravis

* Myositis

* Narcolepsy

* Neonatal Lupus

* Neuromyelitis optica

* Neutropenia

* Ocular cicatricial pemphigoid

* Optic neuritis

* Palindromic rheumatism (PR)

* PANDAS

* Parkinson's disease

* Paraneoplastic cerebellar degeneration (PCD)

* Paroxysmal nocturnal hemoglobinuria (PNH)

* Parry Romberg syndrome

* Pars planitis (peripheral uveitis)

* Parsonage-Turner syndrome

* Pemphigus

* Peripheral neuropathy

* Perivenous encephalomyelitis

* Pernicious anemia (PA)

* POEMS syndrome

* Polyarteritis nodosa

* Polyglandular syndromes type I, II, III

* Polymyalgia rheumatica

* Polymyositis

* Postmyocardial infarction syndrome

* Postpericardiotomy syndrome

* Primary biliary cirrhosis

* Primary sclerosing cholangitis

* Progesterone dermatitis

* Psoriasis

* Psoriatic arthritis

* Pure red cell aplasia (PRCA)

* Pyoderma gangrenosum

* Raynaud’s phenomenon

* Reactive Arthritis

* Reflex sympathetic dystrophy

* Relapsing polychondritis

* Restless legs syndrome (RLS)

* Retroperitoneal fibrosis

* Rheumatic fever

* Rheumatoid arthritis

* Sarcoidosis

* Schmidt syndrome

* Scleritis

* Scleroderma

* Sjögren’s syndrome

* Sperm & testicular autoimmunity

* Stiff person syndrome (SPS)

* Subacute bacterial endocarditis (SBE)

* Susac’s syndrome

* Sympathetic ophthalmia (SO)

* Takayasu’s arteritis

* Temporal arteritis/Giant cell arteritis

* Thrombocytopenic purpura (TTP)

* Tolosa-Hunt syndrome (THS)

* Transverse myelitis

* Type 1 diabetes

* Ulcerative colitis (UC)

* Undifferentiated connective tissue disease (UCTD)

* Uveitis

* Vasculitis

* Vitiligo

* Vogt-Koyanagi-Harada Disease

Wonder how many doctors are paying attention?

~shared from Jodi Wilson

[joga-blog]

Absolute Eosinophil Count: A Key Marker in Allergic Diseases and Beyond

Eosinophils are a type of white blood cell involved in the immune response against parasites, allergens, and infections. Absolute Eosinophil Count (AEC) is a measure of the number of eosinophils present in a microliter of blood. AEC is an important parameter used in diagnosing and monitoring various medical conditions.

Normal Range of AEC:

The normal range of Absolute Eosinophil Count (AEC) may vary slightly depending on the laboratory and the method of analysis used. However, in general, the normal range for AEC is between 30 to 350 eosinophils per microliter of blood.

Clinical Significance:

Elevated AEC levels, known as eosinophilia, can indicate several underlying health conditions, including allergies, parasitic infections, autoimmune diseases, and certain types of cancers. Conversely, low AEC levels may be observed in conditions such as aplastic anemia, drug toxicity, or overwhelming infections.

Causes of Elevated AEC:

1. Allergic Disorders:

Allergic conditions such as asthma, allergic rhinitis, atopic dermatitis, and allergic reactions to medications can cause eosinophilia.

2. Parasitic Infections:

Helminth infections, such as roundworms, tapeworms, and flukes, are common causes of eosinophilia.

3. Autoimmune Diseases:

Conditions like eosinophilic granulomatosis with polyangiitis (formerly known as Churg-Strauss syndrome) and systemic lupus erythematosus can lead to elevated AEC levels.

4.Hypereosinophilic Syndrome (HES): 

HES is a rare disorder characterized by persistent eosinophilia and organ damage. It requires careful evaluation and management by a healthcare professional.

Diagnostic Evaluation:

When eosinophilia is detected, further diagnostic tests are often conducted to identify the underlying cause. This may include:

- Comprehensive medical history and physical examination

- Laboratory tests such as complete blood count (CBC), serum immunoglobulin levels, and specific IgE testing

- Imaging studies like chest X-rays, CT scans, or ultrasound to assess organ involvement

- Biopsy of affected tissues, if necessary

Treatment and Management:

The treatment of eosinophilia depends on the underlying cause. In cases of allergic conditions, antihistamines, corticosteroids, and allergen avoidance measures may be recommended. Parasitic infections are treated with anthelmintic medications. In more severe cases, immunosuppressive therapy or targeted biologic agents may be prescribed to modulate the immune response.

Conclusion:

Absolute Eosinophil Count is a valuable marker used in the diagnosis and management of various medical conditions. Understanding the significance of AEC levels and their association with underlying diseases, healthcare professionals are providing timely and appropriate interventions for patients.

It is important to note that AEC results should always be interpreted in conjunction with clinical findings and other laboratory tests to make an accurate diagnosis and formulate an effective treatment plan. Patients with persistently elevated AEC levels should seek medical attention for further evaluation and management.

[treatmentguidelines]

Churg strauss syndrome

Churg Strauss Syndrome, also known as eosinophilic granulomatosis with polyangiitis (EGPA), is a rare autoimmune disease that affects multiple organs, particularly the lungs, skin, and blood vessels. In this blog post, we will delve into the various aspects of Churg Strauss Syndrome, including its causes, symptoms, diagnosis, treatments, and potential complications. We will also explore the lifestyle changes and self-care measures that can help patients manage their condition. Furthermore, we will discuss the support groups and resources available for individuals with Churg Strauss Syndrome, as well as the latest research and advancements in understanding this syndrome. Finally, we will compare it with other similar autoimmune diseases, discuss the prognosis and long-term outlook for patients, and examine prevention and risk reduction strategies for Churg Strauss Syndrome. Stay tuned for a comprehensive overview of this complex syndrome and how it affects those diagnosed with it.

What Is Churg Strauss Syndrome?

Churg Strauss Syndrome, also known as eosinophilic granulomatosis with polyangiitis (EGPA), is a rare autoimmune disorder that causes inflammation of the blood vessels. It primarily affects the small and medium-sized blood vessels, especially those in the lungs, skin, nerves, and gastrointestinal tract. The syndrome is characterized by the accumulation of eosinophils, a type of white blood cell, in various organs and tissues. These eosinophils release harmful substances that cause damage to the blood vessels, leading to a wide range of symptoms and complications. One of the key features of Churg Strauss Syndrome is the presence of asthma and allergic rhinitis in most patients. Many individuals with the syndrome have a long history of asthma before the onset of other symptoms. Asthma symptoms can worsen along with the progression of the syndrome. In some cases, previously well-controlled asthma may become more difficult to manage. Churg Strauss Syndrome can also affect other organs, such as the heart, kidneys, and nervous system. This can result in symptoms such as chest pain, heart palpitations, kidney problems, and nerve damage. In terms of its cause, the exact triggers for Churg Strauss Syndrome remain unclear. However, research suggests that a combination of genetic and environmental factors may play a role in its development. Some studies have identified specific genetic mutations that are more common in individuals with the syndrome. Environmental factors, such as exposure to certain chemicals or allergens, may trigger an abnormal immune response in susceptible individuals. Further research is needed to fully understand the underlying mechanisms. Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare autoimmune disorder The syndrome primarily affects the small and medium-sized blood vessels Churg Strauss Syndrome is characterized by the accumulation of eosinophils Common Symptoms: • Asthma • Allergic rhinitis • Skin rashes • Nerve damage • Chest pain

Causes Of Churg Strauss Syndrome

The exact cause of Churg Strauss Syndrome is still unknown. However, researchers believe that it is an autoimmune disorder, meaning that the body's immune system mistakenly attacks healthy tissues and organs. It is believed that certain genetic factors play a role in the development of the syndrome, as it tends to run in families. Environmental factors, such as exposure to allergens or certain medications, may also contribute to the development of the condition. Additionally, it has been observed that individuals with certain conditions, such as asthma or allergies, have a higher risk of developing Churg Strauss Syndrome. This suggests that there may be a link between these conditions and the development of the syndrome. However, more research is needed to fully understand the relationship between these factors and the development of Churg Strauss Syndrome. Furthermore, it is important to note that Churg Strauss Syndrome is a rare condition. It is estimated to affect only a small number of individuals worldwide. While the exact causes are still unclear, researchers are continuously studying the syndrome in order to gain a better understanding of its underlying mechanisms and factors that contribute to its development.

Symptoms And Manifestations Of The Syndrome

Churg Strauss Syndrome, also known as eosinophilic granulomatosis with polyangiitis (EGPA), is a rare autoimmune disease that causes inflammation in blood vessels. This condition primarily affects small and medium-sized arteries, leading to a range of symptoms and manifestations. One of the hallmark symptoms of Churg Strauss Syndrome is asthma. Many patients with this syndrome have a history of asthma or allergic rhinitis. The asthma may become more severe and difficult to manage as the syndrome progresses. Patients may also experience recurrent sinusitis, which can cause facial pain and congestion. Another common manifestation of Churg Strauss Syndrome is eosinophilia. Eosinophils are a type of white blood cell that play a role in allergic reactions. In EGPA, the body produces an excess of eosinophils, leading to high levels of these cells in the blood. Eosinophilia can cause damage to organs and tissues throughout the body. In addition to asthma and eosinophilia, patients with Churg Strauss Syndrome may develop vasculitis. Vasculitis is inflammation of blood vessels, which can restrict blood flow and damage organs. Symptoms of vasculitis can vary depending on the organs affected, but may include skin rashes, nerve damage, gastrointestinal problems, and kidney dysfunction. Other manifestations of Churg Strauss Syndrome can include cardiac involvement, such as myocarditis or heart rhythm abnormalities, and pulmonary complications, such as pulmonary infiltrates and nodules. Patients may also experience musculoskeletal symptoms like muscle pain and joint inflammation. It is important to note that the symptoms and manifestations of Churg Strauss Syndrome can vary greatly from person to person. Some individuals may have mild symptoms and a relatively benign disease course, while others may experience more severe symptoms and complications. Early recognition and diagnosis of the syndrome is crucial to initiate appropriate treatment and management options.

Diagnosis And Medical Tests For Churg Strauss Syndrome

When it comes to diagnosing Churg Strauss Syndrome, a thorough medical evaluation is essential. As an autoimmune disease that affects the blood vessels, accurate diagnosis is crucial for determining the appropriate treatment plan. Doctors often rely on a combination of medical tests and clinical symptoms to diagnose this syndrome. One of the key tests used for the diagnosis of Churg Strauss Syndrome is a blood test. This test helps in assessing the levels of eosinophils, which are a type of white blood cells. Elevated levels of eosinophils can indicate the presence of inflammation in the body, which is a characteristic feature of this syndrome. Additionally, the blood test also helps in measuring other markers of inflammation and evaluating the overall health of the patient. In addition to the blood test, a biopsy may also be performed to confirm the diagnosis. A small sample of the affected tissue, such as a sample from the lungs or skin, is taken and examined under a microscope. This can help identify the presence of eosinophils and confirm the diagnosis of Churg Strauss Syndrome. - Furthermore, imaging tests such as X-rays, CT scans, and MRIs may be used to visualize the affected organs and detect any abnormalities. These tests are particularly useful in assessing the extent of organ damage or the presence of complications associated with Churg Strauss Syndrome. Medical Tests for Diagnosis of Churg Strauss Syndrome Purpose Blood test To assess eosinophil levels and measure markers of inflammation Biopsy To confirm the diagnosis by examining tissue samples under a microscope Imaging tests To visualize affected organs and detect abnormalities Overall, the diagnosis of Churg Strauss Syndrome requires a comprehensive approach involving various medical tests and clinical evaluations. Prompt and accurate diagnosis is crucial for starting appropriate treatment and managing the condition effectively.

Treatments And Management Options

Treatments And Management Options for Churg Strauss Syndrome Churg Strauss Syndrome, also known as eosinophilic granulomatosis with polyangiitis (EGPA), is a rare autoimmune disease that affects multiple organs. It is characterized by the inflammation of blood vessels, causing damage to various tissues in the body. While there is no cure for Churg Strauss Syndrome, there are several treatment options available to manage the symptoms and improve the quality of life for patients. Medication: One of the primary goals in the treatment of Churg Strauss Syndrome is to suppress the immune system and reduce inflammation. This is typically achieved through the use of medications such as corticosteroids and immunosuppressants. Corticosteroids, such as prednisone, help to reduce inflammation and control symptoms. However, long-term use of corticosteroids can lead to side effects, so it is important to find the lowest effective dose. Immunosuppressants, such as azathioprine or methotrexate, may be prescribed in combination with corticosteroids to further suppress the immune response. Biologic Therapy: In some cases, biologic therapies may be recommended for individuals with Churg Strauss Syndrome. Biologic drugs, such as mepolizumab and rituximab, target specific molecules or cells involved in the immune response. Mepolizumab, an anti-interleukin-5 antibody, has shown effectiveness in reducing the frequency of asthma exacerbations and improving lung function in patients with EGPA. Rituximab, a monoclonal antibody, can selectively deplete B cells, which play a role in the immune response. These biologic therapies are usually used when other treatments have not provided sufficient relief. Monitoring and Supportive Care: Regular monitoring of Churg Strauss Syndrome is crucial to assess the response to treatment and detect any potential complications. This may involve blood tests, imaging studies, and lung function tests. Supportive care measures, such as maintaining a healthy lifestyle, managing symptoms, and preventing infections, are also essential for the overall management of the disease. It is important for individuals with Churg Strauss Syndrome to work closely with a healthcare team, including rheumatologists and pulmonologists, to ensure optimal management of the condition. Conclusion: While Churg Strauss Syndrome can be a challenging and complex disease to manage, there are treatment options available to help control symptoms and improve the quality of life for patients. Medication, including corticosteroids and immunosuppressants, is commonly used to reduce inflammation and suppress the immune response. Biologic therapies, such as mepolizumab and rituximab, may be considered when other treatments are ineffective. Regular monitoring and supportive care are essential components of managing this rare autoimmune disease.

Potential Complications And Risks

Churg Strauss syndrome, also known as eosinophilic granulomatosis with polyangiitis (EGPA), is a rare autoimmune disease that causes inflammation of blood vessels. While the exact cause of this syndrome is yet to be determined, it is believed to be a combination of genetic and environmental factors. It primarily affects the small and medium-sized blood vessels, leading to a wide range of symptoms and manifestations. Churg Strauss syndrome can potentially lead to various complications and pose certain risks to individuals diagnosed with the condition. One of the most significant complications is the potential damage to vital organs as a result of vasculitis. The inflammation of blood vessels can restrict blood flow, leading to organ dysfunction and even organ failure. The organs most commonly affected include the lungs, heart, gastrointestinal tract, skin, and nervous system. It is crucial for individuals with Churg Strauss syndrome to be aware of these potential complications and seek immediate medical attention if they experience any symptoms related to organ dysfunction. In addition to organ involvement, individuals with Churg Strauss syndrome may also experience respiratory complications. Asthma, which is often present in patients with this syndrome, can worsen and become difficult to manage. Severe asthma attacks may require intensive medical intervention and can be life-threatening if not promptly treated. Furthermore, the inflammation in the respiratory system can lead to other complications such as chronic sinusitis, recurrent bronchitis, and lung scarring, which can impair lung function over time. - Table: Potential Complications and Risks of Churg Strauss Syndrome Complications Risks Organ dysfunction/failure Restricted blood flow due to vasculitis Respiratory complications Worsening asthma, chronic sinusitis, lung scarring Cardiovascular complications Inflammation of blood vessels in the heart, heart attack Gastrointestinal complications Inflammation of blood vessels in the gastrointestinal tract, digestive issues, bowel perforation Neurological complications Inflammation of blood vessels in the nervous system, nerve damage, stroke Another potential complication associated with Churg Strauss syndrome involves the cardiovascular system. Inflammation of blood vessels in the heart can lead to the development of coronary artery disease and increase the risk of heart attack. It is important for individuals with this syndrome to manage their cardiovascular health through regular check-ups and appropriate interventions, such as medication and lifestyle modifications. Gastrointestinal complications may also arise in people with Churg Strauss syndrome. Inflammation of blood vessels in the gastrointestinal tract can cause abdominal pain, digestive issues, and in severe cases, bowel perforation. Regular monitoring of gastrointestinal symptoms, along with appropriate medical management, is crucial in preventing and managing these complications. Additionally, Churg Strauss syndrome can affect the nervous system, leading to neurological complications. Inflammation of blood vessels in the nervous system can result in nerve damage and increase the risk of stroke. Neurological symptoms may include numbness, tingling, weakness, difficulty in coordination, and changes in vision. Close monitoring and early intervention are essential to prevent further deterioration and minimize the impact on the individual's quality of life. In conclusion, Churg Strauss syndrome carries potential complications and risks that individuals should be aware of. Organ dysfunction, respiratory complications, cardiovascular issues, gastrointestinal problems, and neurological manifestations are among the possible consequences of this rare autoimmune disease. By understanding these potential complications and seeking appropriate medical care, individuals with Churg Strauss syndrome can better manage their condition and mitigate the risks associated with it.

Lifestyle Changes And Self-Care For Patients

Living with Churg Strauss Syndrome can be challenging, but making certain lifestyle changes and taking self-care measures can greatly improve the quality of life for patients. These changes and practices can help patients manage symptoms, prevent flare-ups, and reduce the overall impact of the syndrome on their daily lives. 1. Follow a Healthy Diet: Adopting a healthy and balanced diet is crucial for patients with Churg Strauss Syndrome. Consuming a variety of fruits, vegetables, whole grains, lean proteins, and healthy fats can support the immune system and help reduce inflammation. It is important to limit processed foods, sugary snacks, and foods high in saturated fats, as they can exacerbate symptoms and contribute to overall health issues. 2. Regular Exercise: Engaging in regular physical activity is highly beneficial for patients with Churg Strauss Syndrome. Exercise can help improve cardiovascular health, strengthen muscles, and enhance overall well-being. However, it is important to consult with a healthcare professional before starting any exercise regimen to ensure it is suitable for individual circumstances. 3. Stress Management: Managing stress is crucial for patients with Churg Strauss Syndrome, as stress can trigger flare-ups and worsen symptoms. Engaging in stress-reducing activities such as meditation, deep breathing exercises, yoga, or spending time in nature can help alleviate stress and promote relaxation. It is also beneficial to establish a support network of family, friends, or support groups to share experiences and receive emotional support. 4. Adequate Rest and Sleep: Getting enough rest and quality sleep is essential for patients with Churg Strauss Syndrome. Fatigue is a common symptom of the syndrome, and ensuring adequate rest can help manage its impact. Establishing a regular sleep schedule, creating a comfortable sleep environment, and practicing good sleep hygiene can contribute to better sleep quality. 5. Medication Management: Strictly adhering to prescribed medications and treatment plans is crucial for managing Churg Strauss Syndrome. Patients should follow the recommended dosage and schedule for medications, and communicate any concerns or side effects to their healthcare provider. It is important not to alter or stop medication without medical advice. 6. Avoidance of Triggers: Identifying and avoiding triggers that can worsen symptoms or trigger flare-ups is important for patients with Churg Strauss Syndrome. Common triggers include allergens, environmental pollutants, and certain medications. By recognizing and avoiding these triggers, patients can reduce the frequency and intensity of symptoms. By implementing these lifestyle changes and practicing self-care, patients with Churg Strauss Syndrome can take an active role in managing their condition and improving their overall well-being. It is important to work closely with healthcare professionals to develop personalized approaches and strategies that meet individual needs and circumstances.

Support Groups And Resources For Individuals With Churg Strauss Syndrome

Support groups and resources play a crucial role in providing emotional support, information, and resources to individuals diagnosed with Churg Strauss Syndrome. Being diagnosed with such a rare and complex autoimmune disease can be overwhelming and isolating. Read the full article

[futuremarketshubham]

The Global Eosinophilic Granulomatosis with Polyangiitis Treatment Market Is Expected to Register Growth at 5.2% CAGR through 2033- FMI Study

The global eosinophilic granulomatosis with polyangiitis treatmentmarket is currently valued at US$ 173.8 Million in 2023 and is anticipated to expand at a CAGR of  5.2%. Owing to the technological advances in healthcare the market is likely to propel to US$ 288.5 Million by 2033.

The growing occurrences of churg strauss syndrome and other allergic reactions and asthma, rising geriatric population, and growing incidences of churg Strauss syndrome in children are expected to drive the growth of the market during the assessment period.

The increasing awareness among patients regarding this condition and the availability of effective therapeutics are projected to bolster the eosinophilic granulomatosis with polyangiitis treatment market in developed economies. Furthermore, with the rising support from government organizations and the development of the healthcare facilities and infrastructure are projected to supplement the development of the overall market in the forecast period.

The development of modern therapeutics and the increasing number of players with a strong drug pipeline are considered as the key factors that are likely to contribute substantially towards the development of the global eosinophilic granulomatosis with polyangiitis treatment market in the next few years.

The manufacturers are involved in the production of eosinophilic granulomatosis with polyangiitis treatment market in a larger capacity. Research and innovation are also conducted to launch innovative products for eosinophilic granulomatosis with polyangiitis therapeutics.

North America dominates the eosinophilic granulomatosis with polyangiitis treatment market due to the presence of key market players' presence, along with recent product launches and established healthcare infrastructure, which will accelerate the market's growth in the region. The significant R&D investments in Europe abode well for market growth.

Download Sample Report to learn about recent in the EosinophilicGranulomatosis with Polyangiitis Treatment Marketby FMI @ https://www.futuremarketinsights.com/reports/sample/rep-gb-16455

Key Takeaways from the Market Study

As of 2023, the eosinophilic granulomatosis with polyangiitis treatment market was valued at US$ 173.8Million

From 2023 to 2033, the eosinophilic granulomatosis with polyangiitis treatment industry is poised to grow at 5.2% CAGR

By 2033, the eosinophilic granulomatosis with polyangiitis treatment market is slated to reach a valuation of US$ 288.5 Million

Based on the distribution channel, hospital pharmacy segment accounts for   market share of 35.7% during the forecast period. 

China is poised to yield a CAGR of 4.8% with respect eosinophilic granulomatosis with polyangiitis treatment in 2033.

“Growing healthcare spending and growing the incidence of asthma across the world and rapid rise in the geriatric population are expected to radically transform the market in the coming years,” comments an analyst at FMI.

Competitive Landscape

Some of the key players present in the global eosinophilic granulomatosis with polyangiitis treatment markets are Genentech Inc., F. Hoffmann-La Roche AG, Cephalon Inc., Teva Pharmaceutical Industries Ltd., Amgen Inc., Sanofi S.A., Koninklijke DSM N.V, AstraZeneca, Novartis International AG, GlaxoSmithKline LLC, Baxter Healthcare Corporation and others.

The research report presents a comprehensive assessment of the market and contains thoughtful insights, facts, historical data, and statistically supported and industry-validated market data. It also contains projections using a suitable set of assumptions and methodologies. The research report provides analysis and information according to market segments such as geographies, application, and industries.

In April 2021 -- Genentech, a member of the Roche Group announced that the U.S. Food and Drug Administration (FDA) has approved the company’s supplemental Biologics License Application for Xolair® (omalizumab) prefilled syringe for self-injection across all approved U.S. indications. Xolair is the only FDA-approved biologic designed to target and block immunoglobulin E (IgE) for the treatment of moderate to severe persistent allergic asthma, chronic idiopathic urticaria (CIU) and nasal polyps.

In December 2020 - Amgen announced that the U.S. Food and Drug Administration (FDA) has approved RIABNI™ (rituximab-arrx), a biosimilar to Rituxan® (rituximab), for the treatment of adult patients with Non-Hodgkin's Lymphoma (NHL), Chronic Lymphocytic Leukemia (CLL), Granulomatosis with Polyangiitis (GPA) (Wegener's Granulomatosis), and Microscopic Polyangiitis (MPA).

More Valuable Insights Available

FMI, in its new offering, presents an unbiased analysis of the market, presenting historical demand data (2018 to 2022) and forecast statistics for the period of 2023 to 2033.

The study divulges essential insight into eosinophilic granulomatosis with polyangiitis treatment market by drug class (Steroids, Immunosuppressant, Biologics, Immune Globulins) by Route of Administration (Oral, Intravenous, Intramuscular) by Distribution Channel (Hospital Pharmacies, Drug stores, Retail Pharmacies, Online Pharmacies) by Region - Global Forecast 2023 to 2033

About the Healthcare Division at Future Market Insights

The healthcare team at Future Market Insights offers expert analysis, time efficient research, and strategic recommendations with an objective to provide authentic insights and accurate results to help clients worldwide. With a repertoire of over 100+ reports and 1 million+ data points, the team has been analyzing the industry lucidly in 50+ countries for over a decade. The team provides a brief analysis on key trends including competitive landscape, profit margin, and research development efforts.

About Future Market Insights (FMI)

Future Market Insights (FMI) is a leading provider of market intelligence and consulting services, serving clients in over 150 countries. FMI is headquartered in Dubai, and has delivery centers in the UK, U.S. and India. FMI's latest market research reports and industry analysis help businesses navigate challenges and make critical decisions with confidence and clarity amidst breakneck competition. Our customized and syndicated market research reports deliver actionable insights that drive sustainable growth. A team of expert-led analysts at FMI continuously tracks emerging trends and events in a broad range of industries to ensure that our clients prepare for the evolving needs of their consumers.

Key Companies Profiled

Genentech Inc

F. Hoffmann-La Roche AG

Cephalon Inc.

Teva Pharmaceutical Industries Ltd.

Amgen Inc.

Sanofi S.A.

Koninklijke DSM N.V

AstraZeneca

Novartis International AG

GlaxoSmithKline LLC

Baxter Healthcare Corporation

Key Segments Covered in Eosinophilic Granulomatosis with Polyangiitis Treatment Market Industry Survey:

Steroids

Immunosuppressant

Biologics

Immune Globulins

Eosinophilic Granulomatosis with Polyangiitis Treatment Market by Route of Administration:

Oral

Intravenous

Intramuscular

Eosinophilic Granulomatosis with Polyangiitis Treatment Market by Distribution Channel:

Hospital Pharmacies

Drug stores

Retail Pharmacies

Online Pharmacies

Eosinophilic Granulomatosis with Polyangiitis Treatment Market by Region:

North America

Latin America

Europe

South Asia

East Asia

Oceania

Middle East & Africa (MEA)

[drpedi07]

Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss syndrome)- Diagnostic criteria Calculator

In 1951, Churg and Strauss first described the syndrome in 13 patients who had asthma, eosinophilia, granulomatous inflammation, necrotizing systemic vasculitis, and necrotizing glomerulonephritis.

[drshalabhsharma1]

Factors of Nasal Polyps And how Nasal Polyps Develop

Nasal polyps are soft, painless, noncancerous growths that develop in the lining of the nasal passages and sinuses. They are typically teardrop-shaped or round and range in size from a few millimeters to several centimeters in diameter.

Nasal polyps can occur in one or both nostrils and may grow large enough to obstruct the nasal passages, making it difficult to breathe through the nose. They can also cause a runny or stuffy nose, postnasal drip, loss of smell or taste, and sinus pressure or pain.

The exact cause of nasal polyps is not clear, but they are thought to be associated with chronic inflammation of the nasal and sinus tissues, allergies, asthma, infections, and certain medications. Treatment for nasal polyps may include medications such as nasal corticosteroids, antibiotics, or antihistamines, and in some cases, surgery may be necessary to remove the polyps.

Dr. Shalabh Sharma is the best ENT doctor in vasant vihar offering general check- ups, habitual complaint operation, & technical treatments. He has been rehearsing as an ENT surgeon since the once 25 times. Bringing with him times of clinical experience and surgical moxie, his clinic offers state of the art installations in a warm and relaxed terrain.

Factors contribute to polyp formation

The exact causes of nasal polyps are not fully understood, but there are several factors that are believed to contribute to their formation. These include:

Chronic inflammation: Nasal polyps are often associated with chronic inflammation of the nasal and sinus tissues. This inflammation can be caused by allergies, infections, or other irritants.

Allergies: People with allergies are more likely to develop nasal polyps. Allergic reactions can cause inflammation in the nasal passages and sinuses, which can lead to the formation of polyps.

Asthma: People with asthma are also at an increased risk of developing nasal polyps. The chronic inflammation associated with asthma can affect the nasal passages and sinuses, leading to the formation of polyps.

Genetic factors: There may be a genetic component to nasal polyp formation. Some studies suggest that people with a family history of nasal polyps may be more likely to develop them.

Medications: Certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and aspirin, can trigger the formation of nasal polyps in some people.

Other medical conditions: People with certain medical conditions, such as cystic fibrosis, Churg-Strauss syndrome, or Kartagener's syndrome, may be more likely to develop nasal polyps.

FESS the best surgical treatment

Functional endoscopic sinus surgery (FESS) is a common surgical treatment for nasal polyps and other sinus-related conditions. FESS is considered the best surgical treatment for several reasons:

Minimally invasive: FESS is a minimally invasive surgical procedure that is performed using an endoscope. This means that the surgeon can access the nasal and sinus cavities through the nostrils, without making any external incisions.

Precise: FESS allows the surgeon to visualize the nasal and sinus cavities in great detail, using a high-definition camera attached to the endoscope. This enables them to remove polyps and other tissues with precision, while minimizing damage to surrounding tissues.

Effective: FESS has been shown to be an effective treatment for nasal polyps and other sinus-related conditions. The procedure can help to improve symptoms such as nasal congestion, difficulty breathing, and reduced sense of smell.

Quick recovery time: Because FESS is a minimally invasive procedure, it typically requires less recovery time than traditional open surgery. Most patients are able to return to normal activities within a few days to a week after the procedure.

Low complication rate: FESS has a low complication rate, and serious complications are rare. However, as with any surgical procedure, there is a small risk of bleeding, infection, or other complications.

Can the polyps occur again?

Yes, nasal polyps can recur after treatment, including after surgical removal. Recurrence rates vary depending on the individual and the specific treatment used. Some studies have found that up to 50% of people may experience polyp recurrence after surgery.

However, the risk of recurrence can be reduced by taking steps to address the underlying causes of the polyps, such as managing allergy, controlling asthma, treating infections. Regular use of nasal corticosteroids after surgery may also help prevent polyp regrowth.

As we mentioned, follow-up appointments with the surgeon are important after treatment to monitor for polyp recurrence and adjust the treatment plan if necessary. In some cases, additional treatments such as additional surgery or alternative medications may be needed if polyps do recur.

[bestotologydoctorinindia]

What Are Nasal Polyps Explained By Dr. Ameet Kishore

Introduction

Nasal polyps are benign lesions affecting around four percent of the population. It is a common and painless condition.  Patients with nasal polyps may experience headache, nasal obstruction, coughing, and rhinorrhoea.

Nasal polyps are a small-circular growth, resembling a small cyst in the nasal cavity. It affects the vitality, emotional state, and general health of the patient.

What Are Nasal Polyps?

Nasal polyps are non-carcinogen growth of mucosa in the nasal cavity of your nose. They do not show any symptoms if they are smaller in size. Nasal polyp can occur in any age group, but adults are at increased risk for this condition. The doctor may prescribe medications for mild to moderate cases.  In severe cases, the patient may undergo surgery. There is a high incidence of their recurrence.

What Are The Symptoms Of Nasal Polyps?

Patients with nasal polyps may experience the following symptoms:

Rhinorrhoea (Runny Nose)

Nasal obstruction

Snoring

Frequent nose bleeding

Facial Pain and Headache

Toothache

Head and forehead pressure

Postnasal drip

Reduces sense of smell

Loss of sense of taste

What Are The Causes Of Nasal Polyps?

Following are the major causes of nasal polyps:

Family history and hereditary

Underlying conditions such as Asthma and Cystic fibrosis

Hey fever

Churg-Strauss syndrome

Sensitivity to NSAIDs

Allergy towards any irritation

Chronic sinus infections

How The Doctor Performs Diagnose The Nasal Polyps?

Polyps are visible with the help of a simple lighted instrument like a medical torch. Some diagnostic tests for nasal polyps are:

Nasal endoscopy

Allergy tests

Test for cystic fibrosis(CF is an inherited condition that affects the gland production of mucous, sweat, tear, saliva, and digestive juices)

A blood test to rule out vitamin-D deficiency as it may result in nasal polyps)

What Are The Treatment Options Of Nasal Polyps?

Following are some of the treatment options for nasal polyps:

Medication: The doctor may prescribe anti-inflammatory drugs to reduce the size of polyps and managing symptoms. The doctor may also recommend topical nasal steroids, sprays, orals (like tablets), or injections.

Nasal sprays can reduce the inflammation and sensation of having a blockage inside the nose by shrinking the polyp. There is a high chance of recurrence after stopping the treatment. Take steroids only as per the directions of the doctor. It may have side-effects like a rise in blood pressure,increased pressure in the eyes, and fluid accumulation.

The doctor may also recommend antihistamines and antibiotics. They can treat allergies and sinus infections and can reduce nasal inflammation.

Surgery: Surgery is another option for managing nasal polyps.The type of surgery depends upon the size of the polyp.Nasal polyps reappeared in around 15% of the patients. Sometimes, patients need to undergo multiple surgeries.

Doctors perform polypectomy for small nasal polyps.The surgeon uses a small suction device or a micro-blade. The doctor cuts and removes soft tissues alongside mucosa. For large polyps, the patient may undergo an endoscopic sinus surgery. The doctor uses an endoscope, a thin and long tube with a camera at the other end, to perform the surgery.

After surgery, the doctor may prescribe nasal sprays and washes to reduce the risk of recurrence. The side effect of nasal surgery includes nose bleeding and nose infections. The patients may also experience a reduction in smell sensation.

What Are The Complications Of Nasal Polyps?

Nasal polyps can create complications in normal breathing because it blocks normal airflow and drainage of fluid. It also creates long-term irritations and inflammation. Some complications of nasal polyps are:

Obstructive sleep apnoea

Asthma flare-up

Sinus infections

How To Prevent Nasal Polyps?

Following are some of the ways to reduce the occurrence of nasal polyps:

Maintain good hygiene: Frequently wash your hand with hand-wash.

Humidify your home: Use a good humidifier in your home to maintain the temperature and moisture. It will reduce the chances of infections and inflammation of the nasal cavity.

Avoid exposure to polluted air such as the air containing dust, debris, smoke, chemical fumes, etc.

Conclusion

A nasal polyp is a common and chronic condition. The patient with this condition may experience various nasal symptoms such as a runny nose, breathing difficulties, nasal obstruction, and snoring. The doctor may diagnose the condition through physical evaluation and blood tests. The doctor may also recommend other tests to rule out the presence of certain diseases. The treatment may include medications and surgery.

TAG- Ear Nose Throat Surgeon In India, Best Pediatric ENT Specialists In India, Best Otology Doctor In Delhi

[chickmains]

Mpv normal range

Mpv normal range skin#

Mpv normal range plus#

The main symptoms are asthma, cough, rhinitis and/or sinusitis, pulmonary infiltrates (opacities), pleural effusion… Digestive issuesĪbdominal pain, vomiting or diarrhea may occur when the digestive system is affected. When the lungs are affected, the patient wheezes and suffers from shortness of breath.

Mpv normal range skin#

When the skin is affected, pruritus (itching related to skin conditions), skin rashes, subcutaneous edema, urticaria, mucosal erosions may occur.

Neoplasia (2-7% of cases): lympho or myeloproliferative diseases (abnormal production of certain cells in the bone marrow), Hodgkin’s disease (form of cancer of the lymphatic system).

Certain systemic inflammatory diseases: Churg-Strauss syndrome (characterized by inflammatory destruction of blood vessels), sarcoidosis, rheumatoid arthritis.

Idiopathic hypereosinophilic syndromes (severe eosinophilia).

Infestations and infections: parasitosis and helminths (worms).

Respiratory, food allergies and dermatitis account for up to 80% of eosinophilia cases in industrialized countries: allergic rhinitis (mild eosinophilia), asthma, eczema.

The causes of secondary eosinophilia are varied:

Mpv normal range plus#

Idiopathic hypereosinophilia: with no identifiable cause, is defined as a level of eosinophils greater than 1,500 per mm3 of blood for at least six months, plus organ involvement.

Secondary or reactive: in more than 95% of cases, it is secondary to an acquired pathology.

Primary: in less than 5% of cases, it is genetic, linked to a defect on chromosome 5 and transmitted in an autosomal dominant mode.

Three types of eosinophilia can be distinguished: They play an important role in the immune response -especially parasitic- and in hypersensitivity reactions. The majority of eosinophils are found in tissues at mucosal interfaces with the environment, particularly in the lungs and gastrointestinal tract.

Severe: the level of eosinophils is greater than 5,000 per mm3 of blood.

Moderate: the eosinophil count is between 1,500 and 5,000 per mm3 of blood.

Mild: eosinophil count is between 600 and 1,500 per mm3 of blood.

[lafoiaveugle]

Christ, I hate being sick.

I've spent the last month or so waiting for today. Insurance approved it easily, I caught it before I needed too much prednisone.

Any then Redd got COVID. He's doing better, though I worry about him and long COVID. I don't think he gave it to me (I continuously tested negative at home) but it meant treatment had to be pushed back a week and a half.

I am fairly certain what happened overall is that I went from getting a 500 ml dose to 1000 ml dose and my body was not ready for that. I'll likely talk to my doctor about only doing 500 ml next time.

They couldn't get my veins to work. The first time or two was likely dehydration, then the rest was a panic attack. The super nice nurses told me I wasn't being the worst, gave me oxygen and let me blast Taylor Swift while tried to calm down. Once the IV was in, I fell asleep almost instantly.

At some point I woke up, and the nurse confirmed she would turn up the speed on the IV now that I had been in and out for 90 minutes. It was uncomfortable, but not the worse.

Until it was the worse. I nearly passed out, needing oxygen again. It doesn't help that I have this cough and sinus whatever. I felt like I Was going to throw up, pass out, jump out of my skin....I dunno.

I ended up throwing up towards the end. I am exhausted, achy, sick, though I am keeping food down.

Fuck my body so much.

[eosinophil-hate-blog]

Eosinophil Awareness Week is May 15 - 21, 2022!

This week is Eosinophil Awareness Week! The goal is to raise awareness for eosinophilic disorders, and the impact these rare illnesses have on the people afflicted with them.

[joga-blog]

The Role of Absolute Eosinophil Count Test in Allergic Diseases: A Comprehensive Review

Eosinophils are a type of white blood cell involved in the immune response against parasites, allergens, and infections. Absolute Eosinophil Count (AEC) is a measure of the number of eosinophils present in a microliter of blood. AEC is an important parameter used in diagnosing and monitoring various medical conditions.

Normal Range of AEC:

The normal range of Absolute Eosinophil Count (AEC) may vary slightly depending on the laboratory and the method of analysis used. However, in general, the normal range for AEC is between 30 to 350 eosinophils per microliter of blood.

Clinical Significance:

Elevated AEC levels, known as eosinophilia, can indicate several underlying health conditions, including allergies, parasitic infections, autoimmune diseases, and certain types of cancers. Conversely, low AEC levels may be observed in conditions such as aplastic anemia, drug toxicity, or overwhelming infections.

Causes of Elevated AEC:

1. Allergic Disorders:

Allergic conditions such as asthma, allergic rhinitis, atopic dermatitis, and allergic reactions to medications can cause eosinophilia.

2. Parasitic Infections:

Helminth infections, such as roundworms, tapeworms, and flukes, are common causes of eosinophilia.

3. Autoimmune Diseases:

Conditions like eosinophilic granulomatosis with polyangiitis (formerly known as Churg-Strauss syndrome) and systemic lupus erythematosus can lead to elevated AEC levels.

4.Hypereosinophilic Syndrome (HES): 

HES is a rare disorder characterized by persistent eosinophilia and organ damage. It requires careful evaluation and management by a healthcare professional.

Diagnostic Evaluation:

When eosinophilia is detected, further diagnostic tests are often conducted to identify the underlying cause. This may include:

- Comprehensive medical history and physical examination

- Laboratory tests such as complete blood count (CBC), serum immunoglobulin levels, and specific IgE testing

- Imaging studies like chest X-rays, CT scans, or ultrasound to assess organ involvement

- Biopsy of affected tissues, if necessary

Treatment and Management:

The treatment of eosinophilia depends on the underlying cause. In cases of allergic conditions, antihistamines, corticosteroids, and allergen avoidance measures may be recommended. Parasitic infections are treated with anthelmintic medications. In more severe cases, immunosuppressive therapy or targeted biologic agents may be prescribed to modulate the immune response.

Conclusion:

Absolute Eosinophil Count is a valuable marker used in the diagnosis and management of various medical conditions. Understanding the significance of AEC levels and their association with underlying diseases, healthcare professionals are providing timely and appropriate interventions for patients.

It is important to note that AEC results should always be interpreted in conjunction with clinical findings and other laboratory tests to make an accurate diagnosis and formulate an effective treatment plan. Patients with persistently elevated AEC levels should seek medical attention for further evaluation and management.

[jay99]

Churg Strauss Syndrome (CSS) is caused by inflammation of the blood vessels. It occurs in patients having allergy or asthma. Weight loss, fatigue, numbness, weakness, and nasal passage inflammation are the main symptoms of Churg Strauss syndrome.

[queerautism]

a doctor in the North Carolina sticks almost killed me by leaving severe pneumonia undiagnosed for 3 months, telling my mom she was trying to get drugs for herself because my inhalers weren't working, and having me do breathing tests until i threw up in the parking lot. when i finally got insurance to let me go to a pulmonologist, he took one look at me and said "you're staying here" and i had to be an inpatient in the hospital for a week. my oxy stats were consistently in the 80s for 3 months and my lips and fingernails were always blue and i had to go to the ER for nebulizer treatments at least twice a month and the man still tried to tell me i would just "grow out of it".

turns out part of my left lung had collapsed, and my eosinophils were over 12,000 despite the normal range being less than 500. i found out within the few months after the hospital visit that i have an underlying disorder called churg-strauss syndrome, now known as EGPA. which is usually diagnosed in middle aged cis men, and i had it as a 12-year-old afab (didn't know i was trans yet). the medical system is buck fucking wild

Oh jesus christ that's horrible. Thank you for sharing your experience

[chicago-geniza]

NO FEAR

[spontaneously developing churg-strauss syndrome]

ONE FEAR

[drethanramslay]

Please write Ethan x mc 38 and 8 thank you so much

Thanks for the ask Anon ❤️

You can find the prompt list here.

#8- “Why are you looking at me like that…?”

#38- you can find it here

Warning: Fluff. Forgive me if it's not medically accurate 😅

Taglist: @miyakokurono @trappedinfandoms @openheart12 @sekizincimektup @junggoku @ethandaddyramsey @edith-eggs1 @ethanramseysgirl (let me know if you want to be added or removed from the tag list 😊)

🔹🔹🔹🔹🔹🔹🔹🔹🔹🔹🔹🔹🔹🔹🔹🔹

9:00 pm

A knock resounded on the glass door of Ethan's office. When he looked up from his desk, he found Leah standing there, leaning against the frame.

"Hey Dr. Ramsey. Why are you still here?"

"If you wanted me gone that bad-"

Leah groaned and entered the thin, closing the door behind her. She leaned over the table and found that he was studying a case.

"Is it the nun from room 508?" She asked as she sat down.

"Yeah... It's been driving me crazy since yesterday. I personally think it's Churg-Strauss Syndrome, but somethings are not adding up. I decided to stay over and work it since I'm not feeling sleepy."

"So a night out?"

"Yeah, kind of.. I wouldn't mind if you helped me out. Two brains are better than one."

"Sure Dr. E." She grabbed hold of the charts and started studying it.

11:00 pm

"Ethan?"

"Yeah?" He let out a yawn as he stretched his back. They had shifted to the sofa. Many medical textbooks were lying open all around them. Leah was sitting next to him with his laptop on her lap, and her voluminous hair tied into a messy bun. Her glasses were perched on her nose.

"I'm hungry."

"Hey hungry I'm-"

She smacked him on the shoulder and Ethan chuckled. "I want takeout."

"C'mon let's go. I know a place which sells delicious Chinese food, and is open at this hour. We need a break anyway."

Wearing their jackets, the headed into the cold night. They chatted about the case as they walked down the streets.

"So what happened when they injected her with adrenaline?" Leah asked as she slurped her chicken ramen noodles.

"She became okay but five minutes later she started siezing. Other symptoms- Breathlessness. Wheezing." Ethan said as he bit into his egg roll. They were sitting on a bench in the hospital's garden. Leah sat cross legged, mulling over the symptoms and took another bite of her dumpling.

After chewing the delicious fried rice, Ethan spoke, "And the peculiar thing is that, when we injected the tracer for the MRI scanner, she immediately developed hives."

"Damn. The case is getting stranger and stranger." Ethan hummed in agreement, eyeing her dumplings.

"Sunshine, can I have one of your dumplings?" He gave her the cutest puppy eyes.

"Awwww.... Aren't you cute? I usually don't share but, you can take as long as you give me an egg roll." She ruffled his hair and he just swatted her hand away.

"Deal."

2:45 am

Ethan took his tie and cufflinks off. He rolled his sleeves up until his elbow and unbuttoned the top buttons of his shirt.

Leah stared at every action. His strong forearms, the prominent veins, the stray chest hair, everything.

God, why did I have to fall for such a hot guy?!

"You are staring."

She cleared her throat and went back to get medical textbook.

"Could it be mixed connective tissue disease? Have you quarantined her?" Leah asked, with her legs propped up on the coffee table.

"Yes. Could be an allergy? Can't be safe enough." He replied as he drank his third cup of coffee. He noticed her light blue converse shoes. "Hey, are those new?"

"Yap. And look, they match my scrubs!" She pressed her shoe against her scrub pants. Ethan just stared at the way she was smiling over a pair of shoes.

God, she is so cute. I would move mountains this make her smile like that...

Leah looked at him and saw him looking back at her, with a soft smile playing on his lips. “Why are you looking at me like that…?”

"Nothing. Just seeing how obsessed you are with Converse. I don't get it."

"Converse is like Pokemon... You gotta catch them all."

Ethan rolled his eyes and dived right back into his research.

4:50 am

"It's almost time for the first rounds." Ethan said as he checked his watch.

"We are close E. I think we can crack it." Leah responded.

"You should try it too. It improves the circulation to the head." She called out to him, upside down.

He took his specs off and turned around to see Leah doing a headstand. Her scrub and shirt had rolled down, exposing her toned stomach.

"No I'm good."

"Your loss."

Ethan continued to read the charts when he noticed something. "Wait a second... She used to get rashes when she used to wash copper vessels."

"Also, when I was taking patient history, she said that she joined a missionary at 15, because she wanted to be a celibate. That means using an IUD." Leah added, as she stood up.

"The tracer we use also had copper in it."

"Leah, I think we cracked it."

"Allergic reaction to copper."

"Let's get those tests done." Ethan says as he grabbed his coat.

7:30 am

"Oh my god thank you so much doctor." The nun cried with tears of happiness falling down her cheeks.

"It's our pleasure." Leah said as she gave the patient a smile.

The headed outside and Ethan submitted the charts to the nurses' station. Leah gave out a huge yawn.

"I'm going to pass out." Ethan said as he rubbed his eyes.

Leah nodded and followed him to the on call room. He took out his coat, shoes and belt before settling in the empty bed. Leah took her shoes off as well as her scrub top, leaving her in a black full sleeved shirt.

Instead of heading to another bed, she slipped into the blankets with Ethan and laid her head on his strong bicep.

"Sunshine, what are you doing?"

"Sleeping." She nestled against him and threw her leg on his leg.

"There are legit... Other beds." Ethan yawned out.

"So you want me.... to go?" Leah sleepily asked.

Wrapping his arm around her, he whispered, "No."

They both passed out, cuddling each other into a nice dreamless sleep.

🔹🔹🔹🔹🔹🔹🔹🔹🔹🔹🔹🔹🔹🔹🔹🔹

Last call for writing asks guys:)