#pipetting

[microlitseo]

Using Pipetting Robots: Enhancing Laboratory Efficiency

Contemporary laboratories are under continuous pressure to provide precise results faster, more efficiently, and with fewer human errors. With the advancement of technology, one of the strongest innovations that increases lab productivity is the robot micropipette.

These automated platforms have transformed liquid manipulation for laboratory technicians and scientists with uniformity, efficiency, and reduced fatigue. But what makes pipetting robots so revolutionary in laboratories?

Let us examine the overall use of automated liquid handling instruments and how pipetting robots are improving efficiency in research, diagnostics, pharmaceuticals, and beyond.

What are Pipetting Robots?

Liquid handling robots, also known as pipetting robots, are machines that perform tasks that were previously done manually with the help of pipettes. Pipetting robots have precision mechanisms and software that allow them to add and remove liquids between different samples or containers with great accuracy.

They find application from the extraction of DNA/RNA to drug discovery's high-throughput screening, not only hastening the process but also standardising every step.

Increased Accuracy and Precision

One of the key benefits of pipetting robots is precision. Unlike manual pipetting, whose range of variation is reliant on the expertise and stability of the user, robotic pipetting is controlled by sensors and computer software, which provide precise volumes each time. This removes cross-contamination and human error, both major problems in sensitive experiments, quite considerably.

Increased Throughput

Speed is of the essence in most laboratories. Pipetting robots handle dozens or hundreds of samples in a single pass without interruption and are therefore well-placed for high-throughput applications. This greatly accelerates the rate of experiments and enables scientists to concentrate on interpreting data and analysis rather than monotonous manual work.

Integration with Liquid Handling Instruments

The capacity of pipetting robots is doubled when combined with other liquid handling instruments. These include reservoirs, mixers, and dispensers, which combine with robotic systems to fully automate entire workflows.

Regardless of whether a 96-well PCR plate or serial dilutions are being prepared, the built-in design ensures precision and efficiency in every step.

 Most advanced pipetting robots are designed in modular form, hence they can be tailored to fit the individual needs of experiments.

Transition from Manual to Electronic Devices

Even though traditional micropipettes have been a lab standard for decades, they are increasingly being replaced by more intelligent, ergonomic pipettes. The shift from electronic to manual pipettes is a trend driven by requirements for compatibility, convenience, and consistency.

One of the most important advances in the area is the electronic pipette pump. These pumps mechanise aspiration and dispensing through motorised motion, reducing user fatigue and enhancing the precision of pipetting.

They are particularly valuable in repetitive processes or the handling of volatile chemicals or thixotropic chemicals, where high control is necessary.

How do Electronic Pipettes Complete Automation?

An electronic pipette provides a compromise between manual pipetting and full automation systems. They are best for laboratories that are not yet ready to invest in complete robotic systems but require greater accuracy and convenience.

Electronic pipettes will also have programmable parameters, memory functions, and digital displays, making them significantly more convenient to use than manual ones. They also support semi-automatic installations, which are flexible enough to cater to changing lab needs.

Where robotic pipetting is not yet feasible, due to cost, space, or space considerations. Electronic pipettes offer a compelling alternative for better performance and precision.

Titration Specific Equipment: Welcome to the E-Burette

Accumulation and control are required for titration experiments. That is where the e-burette comes in. While mechanical glass burettes are operated by a manual interface, e-burettes provide direct digital control over titrant flow, improving repeatability as well as constraining parallax error.

Such e-burettes are generally accompanied by data analysis software programs that provide immediate monitoring and recording of the data, enabling scientists to keep safe and reliable records of volume dispensed, flow rate, and endpoint detection.

Coupled with pipetting robots or electronic pipettes, e-burettes maximise complex workflows, best suited for pharma, analytical chem labs, and university research.

Benefits of Pipetting Robots

The following are the primary advantages that pipetting robots provide to laboratories:

Consistency: Collect and prepare sample preparation for multiple experiments. This will be useful and time-saving through your experiments. 

Time-Saving: Saving time is the goal. Automation in the laboratory can enable laboratories to process more samples in a given period, without causing any delay.

Cost-Effectiveness: In a laboratory, the initial cost of acquisition may be high, but pipetting robots save pennies on reagents, mistakes, and labour costs in the long term.

Data Integration: High-end systems can be integrated with Laboratory Information Management Systems (LIMS) to provide real-time tracking and reporting of data.

Scalability: From a small research institution to a big pharma company, pipetting robots can be scaled up or down to fit your operations. As they can be supported due to their enhanced versatility. 

Real-World Applications of Pipetting Robots

Let's look at some actual application areas where pipetting robots are contributing:

Genomics: Automation of sample preparation for next-gen sequencing. This can be helpful for speeding up the experimentation process. 

Drug Discovery: Screening compound libraries by high-throughput screening. Robotics can focus on minute details that may have been missed through the microscope lens in the laboratory.

Diagnostics: Processing hundreds of patient samples daily with minimal error. It will also streamline the experiment and keep the results up to date. 

Food and Beverages: Testing for quality in manufacturing plants, food and beverages need constant scrutiny throughout their manufacturing. Robotic interference may keep the edibles in check by maintaining their quality. 

Environmental Science: Scaled testing of water and soil samples will improve the overall environmental quality. This will also enhance the scientific environmental standards with precise measurements. 

Selecting the Right System for Your Laboratory

When you select a pipetting robot or companion device for your laboratory, think about:

Range of Volume: In a laboratory, which volume do you handle most frequently throughout the experiment?

Throughout Requirements: This depends on the number of experiments you are conducting in a day. For which you need external support for enhancing the process.

Ability to Integrate: Will the robot have to be interfaced to other lab instruments or computer software?

User Interface: Is the system easy to use for your staff?

Budget: What are the purchase price and recurring costs, such as maintenance, consumables, etc.?

Lab instrument companies like Microlit will typically offer demo models and service with reconfiguring of the system to your specific needs.

The Future of Laboratory Automation

As advances in robotics and artificial intelligence continue, pipetting robots will become smart, with needs foreseen, aberrant behaviours detected, and self-optimal performance offered. Through historical data read using machine learning algorithms, future equipment might even predict experimental outcomes or propose process optimisation.

Besides, cloud integration will ensure remote monitoring, as sample progression will be posted in real time from anywhere in the world. With green features like smart reagent management, laboratories in the future will be quicker, greener, and more accurate than they are today.

Conclusion

In the high-speed research and diagnostic settings of today, accuracy and speed are not negotiable. Pipetting robots and associated equipment like micropipettes, electronic pipette pumps, and e-burettes are at the forefront of revolutionising laboratory workflows.

Whether you’re stepping into automation with a reliable electronic pipette or investing in a full-fledged robotic liquid handling system, the benefits are clear: fewer errors, faster results, and better science. With automation becoming the rule rather than the exception, now is the ideal time for labs to get on board, one accurate drop at a time. Are you a laboratory looking to elevate your experiment standards? Contact Microlit today and move towards more efficient experimenting.

[apricotopera]

cant stop looking at this image and crying with laughter. the boots. the matching poses. the matching purple cravats. whats the DEAL

[tarotphil]

this is absolutely just another case of “I like [x thing], I like phil. what if phil did [x thing]” but. I like audio drama podcasts, I like phil. what if phil did audio drama podcasts

[katyaayyyhhgxfhnko9]

Honestly, I can’t find the author of the second pic at all!!!! Wow, I tried really hard, but I don’t go at all, how to draw this saw

[alkemylabz]

several explosions later. ive filled out this years artfight card! come attack me!!

[marianokaz]

Have a drink, Trish!

[mxwhore]

whew what a week!

[liuisi]

so glad i wasn't there for the era of mouth pipetting because i KNOW deep in my bones that i would forget that it's not a straw and just drink whatever substance i was transferring

[microlitseo]

Environmental Factors Affecting Pipetting Accuracy and How to Control Them?

Pipettes are used in the laboratory setting which can be helpful for carrying out various experiments, it can be helpful for elevating the experimenting standards. This will play a significant role in seamlessly transferring liquid from one laboratory equipment to the other. 

Therefore, there can be various environmental factors which can affect pipetting accuracy. Eventually, there are various ways to control the pipettes while managing liquids during an experiment. This will elevate the overall pipetting standards throughout the laboratory experiment. 

Environmental conditions are not only affecting the overall climate change, but it is also creating a gap in getting pipetting accuracy which laboratory technicians crave. This blog is all about the environmental conditions that may affect the pipetting accuracy throughout the experiment and ways which can be followed for controlling inaccuracies. 

Factors Affecting Pipetting Accuracy and Ways to Control

Here are the environmental factors which can be looked upon while carrying out an experiment. These may prevent pipetting inaccuracy. Following this, there are also the ways which can be observed for controlling and achieving accuracy. 

Temperature

When the experiment is carried out in the laboratory, there can be instances where you may experience thermal expansion which can lead to temperature differences between the pipette, the tip, and the liquid. These can create a way for causing thermal expansion and contraction of the air cushion within the pipette. It will eventually lead to inaccurate volume delivery throughout the experiment. 

When a problem arises, there are ways which can prevent the inaccuracies happening due to temperature changes. One of the ways which can be followed is that all the liquid handling instruments involved in an experiment such as samples and pipettes should equilibrate to the same temperature. This will play a significant role in reducing the temperature difference and elevate pipetting standards for an experiment. 

Humidity

Along with the temperature changes, humidity at play can also significantly affect the pipetting accuracy. The low humidity in the pipette may trigger enhanced evaporation of volatile liquids. Eventually, it will affect the final volume and it will leave a mark while conducting an experiment. 

There are ways to prevent humidity from collecting in the pipetting tips, this leads to the process of preventing evaporation by pre-wetting the pipette tip. It will play a significant role in increasing humidity inside the tip and reducing evaporating. Eventually, you can seamlessly carry out the experiment.

Pressure

Among all the inaccuracies in the laboratory while conducting an experiment, there are pressure changes in the barometer during an experiment. This will lead to fluctuations in barometric pressure, which can also affect the volume dispensed. It can also affect the liquid flow from pipette filler to the laboratory equipment.

The pressure changes along with the barometric inaccuracies can be controlled by maintaining an environment during an experiment. This can also play a significant role in maintaining a stable lab environment which can help to minimize these effects. It will also eventually reduce the pipetting inaccuracies.

Control Environment factors and improve Pipetting accuracy

Can laboratory standards be maintained by controlling environment factors which can improve pipetting accuracy? absolutely yes. There are various ways for maintaining environmental standards which can improve environmental accuracy and provide consistent results. 

Maintain a Stable Environment

There are various ways to maintain a stable environment in a laboratory while carrying out an experiment. These ways contain controlling the temperature, maintaining it up to the consistent levels throughout the experiment. This will play a significant role in maintaining the well-controlled laboratory environment. 

Therefore, the humidity control can be a way to maintain the appropriate levels, which will reduce evaporation. This will enhance the experiment standards in the laboratory and also can prevent the liquid loss throughout the experiment. It would maintain the pipetting accuracy throughout the experiment.

While carrying out an experiment, you can also experiment with significant pressure changes due to the environment being not in sync. This can eventually be difficult to control and can lead to potential pressure fluctuations and their impact. It can be controlled by including external pressure controllers such as barometers, which will elevate your experiment standards. 

Equilibrate Sample and Pipettes

While conducting an experiment, you can initially equilibrate the sample and pipettes at the same temperature before pipetting. This will lead to elevating the experiment standards. This will promote laboratory equipment to work in sync throughout the experiment. 

 Use Proper Pipetting Techniques

Through the experiment, there are ways to maintain the consistent speed and force. It will use a consistent speed and force when depressing the plunger. This will reduce the liquid loss throughout the experiment standards. Along with this, you can also check for the immersion depth, through this it will keep the tip  immersed to the correct depth in the liquid throughout the experiment.

Along with this, check for the tip angle while conducting an experiment. It will support through the process which can be carried out by holding pipette vertically during aspiration and during the usage of bottle top dispenser. This would also play a significant role in maintaining the experiment standards, eventually providing accurate results.

Pre-wetting techniques while using pipette can play a major role in maintaining the experiment quality. This will also increase humidity, which will eventually reduce evaporation. It will help you seamlessly transfer liquids from one equipment to another.

Consider Using Positive Displacement Pipettes

While conducting an experiment in a laboratory setting, you may experience extreme temperatures through it. This is where a positive displacement pipette can be a suitable way for carrying out a seamless experiment. Along with this, a piston is attached in the pipette which can be useful for pushing out liquid in accurate volumes.

This will keep you away from getting affected by liquids in high temperatures. It would also keep the accuracy in check as there will be significantly less chances of liquid spill over, as the external pressure is involved while pipetting. 

For handling more precise measurements, using an electronic pipette pump can also enhance accuracy by offering controlled and consistent aspiration and dispensing rates, reducing human error.

Conclusion

Conducting a seamless experiment in a laboratory is serious work, where you may need to keep a check on the environmental factors. As these can affect pipetting standards and also lead  to inaccuracies you may want to keep yourself away from. 

So, there are multiple ways which can be followed for preventing and controlling the uninvited humidity, temperature fluctuations, or pressure changes. These can be controlled during an experiment which supports you through and provides accuracy, can be seen results.  Are you a laboratory technician and dealing with various factors which are affecting your pipetting standards. You can connect with Microlit today and make yourself safe from the unexpected changes throughout the experiment. They are pioneers in laboratory equipment which can give you seamless experience in a laboratory.

[randomcollection-o-stuff]

I think it would be funny for a lab ambience video to have one very quiet "uhoh" in it.

[homesuz]

Afied

[samsdei]

Maxime Pipet

[draconicmaw]

OKAY BUT WHAT IF I WRITE A LAB AU

Consider 👉🏼👈🏼

[1tspcinnamon]

my fuckups in the lab today were innumerable

[thymodyke]

fuck you *wipes you down with 10% bleach and then 70% ethanol*

[adventuresinchemistry]

Learning that my employer explicitly prohibits mouth pipetting blood products…