#seo-yun wood

[tjwlsdlspep9]

서진이네 9회 다시 보기 9화 E09 230421 (풀영상)

서진이네 9회 다시 보기 9화 E09 230421 (풀영상) <<

서진이네 9회 다시 보기 9화 E09 230421 (풀영상)

서진이네 9회 다시 보기 9화 E09 230421 (풀영상)

서진이네 9회 다시 보기 9화 E09 230421 (풀영상)

서진이네 9회 다시 보기 9화 E09 230421 (풀영상)

서진이네 9회 다시 보기 9화 E09 230421 (풀영상)

The Chinese character for 'Chan' is also slightly different. To put it simply, it is the difference whether there is a side of 'bead jade', which is an adjunct of 'chan'.

Today, it is common to write 姜邯贊 following the notation of 《Goryeosa》, but it is also found written as 姜邯瓚. The name of the pagoda written on the pagoda built by Kang Gam-chan at Heungguksa Temple above is written as 姜邯瓚. In the 《Annals of King Jeongjo》 of the Joseon Dynasty, Min Jong-hyeon, the presiding judge of the Joseon Dynasty, made this appeal while mentioning the tower of Heungguksa Temple above. "There is a pagoda at the old site of Heungguksa Temple in Songgyeong (松京: Gaegyeong), and there is a note on the top of the pagoda. It's different. In general, stone engravings are much more reliable than wood engravings. From now on, it would be better to write all Kang Gam-chan's names with the letters chan (瓚)." So, the king followed suit. 從之. Faith, 比諸登榟之本, 不啻懸隔. 《Annals of King Jeongjo》 July 21, 20th year of King Jeongjo. The notation 姜邯贊 is from 《Goryeosa》 compiled in the early Joseon Dynasty, and the stone pagoda of Heungguksa Temple built by Kang Gam-chan says 姜邯瓚. And it is said that Jeongjo followed it as it was. Perhaps this is a story that has been controversial since around this time, Han Chi-yoon in the reign of King Jeongjo also cited this pagoda name in 《Haedong History》 as a basis. "In 《Goryeosa》, his name is written except for the 'bead jade' side, but it should be regarded as accurate that it is written on the tower of Heungguksa Temple." also claimed that

The Heungguk Temple Tower is located in North Korea and cannot be confirmed now, but the inscription remains. Link However, considering that it is mostly recorded as 姜邯贊 and recorded differently only here, there is a possibility that the 'bead jade' side was worn in old age. Tattoo of King Seongjong, the 6th king of Goryeo. He is regarded as a byword for Goryeo diplomats and is a representative of Korean diplomatic history along with Kim Chun-chu of Silla, Lee Ye of Joseon, and Choi Myeong-gil of Joseon.

Although she is perceived as a diplomat, in reality, Seo Hui was not only a diplomat, but also a strategist with a long-term perspective who served as prime minister, and a politician with a sense of principle and responsibility. did. At this time, Sosonnyeong defeated the Goryeo army at Bongsan, advertised that the army was 800,000 strong, and threatened the Goryeo court to surrender, but Goryeo agreed to surrender. Regarding the method of surrender, they were divided between the theory of peace and the theory of peace after giving away the land north of Seogyeong to Liao. In fact, the 800,000 army was a lie. It is today's guess that the army of Sosunning at that time was difficult to exceed 60,000 at most. At that time, Khitan's expeditions could be largely divided into those commanded by Dotong or higher and those not commanded by Dotong. Expeditions led by Dotong often numbered more than 150,000 men, but expeditions not led by Dotong numbered up to six. It was about ten thousand people. Since Xiao Sunning's position at the time was not a Taoist, it is impossible to rule out the possibility that the maximum number of soldiers that Xiao Sunning could command was 60,000 or less.

The bluff worked because Yun Seo-an's vanguard was severely defeated by this force at the forefront of Bongsanseong Fortress. The number of soldiers that Goryeo could mobilize was more than 60,000, but it took a certain amount of time to mobilize and mobilize combatable troops, and it failed to buy time. After the Battle of Bongsanseong, So Son-nyeong loudly shouted, "Surrender unconditionally," to Lee Mong-jeon, an envoy dispatched by Goryeo, and the Goryeo government faced a confusing situation.[15]

[shop-korea]

AMAZON - PRIME - MOST TERRIBLE

HOW - 2 - UPDATE - DRIVER's - TRUE

EXACT - DETAILS - HISPANIC - MALE

MANAGER - HS GRAD - IS A - THIEF

7A - 11A - HOLDS UNTIL - NEXT DAY

BRITISH - SERIES - 'LEVERAGE' -

MANY GARAGES - ELECTRONIC -

AIR - WAVES - AMAZON DRIVER -

WENT - INSIDE - OUR - INFO - AS -

2 - THEIR - LOOKS - VOICE - WE -

DELIVER - WEARING - THEIR XO -

FACE - BODIES - AS -

DIB FERNANDEX FATTY TAKES

PACKAGE - WE - DRANK - OUR

ANTIDOTE - SPRAY - INHALED

AND - AIR - CREMATED - JUST

HIM - MALE - YOUNGER - SUB

ALL - MALES - CREMATED -

OUR - GOAL - 1 ST - LEVEL -

HEAVEN - THEIR - TALK - WITH -

THEIR - CREATOR - ALL - CAN B -

BROUGHT - BACK - UNDER AGE -

100 - HIPNOSIS - AMAZON - YES -

DRIVER - CONTINUES - NEEDED -

SOME - SLEEP - AND - REST -

MEMORY LOSS - OF WHERE -

HE - WAS - R SIDE - PUBLIX -

SW 9 ST - SITTING - BLK XO -

CUSHION - THE UNDERLINE -

PUBLIX - LIME - COLORS FOR -

PAYING - SPONSOR - SO - XO -

EXCITED - REGISTERED - USA -

BIRTHDAY - MON - 05 APR 65 -

'CINDERELLA' - ENGLISH ACTRESS

SAME - BIRTHDAYS - REGISTERED

CHINESE - YEAR - OF - SNAKE - KR

SEO YUN KIM - 'SCHOLAR - WHO

WALKS - THE NIGHT' - DRACULA

NOT - EVEN - NOMINATED - MY

ONLY - HERO - FOREVER - YES

I'M - NOT - SNAKE - SEDUCTIVE

VAIN - THROUGH - CENTURIES

MARRIED - WRONG - GUY OUR

RECORD - OF - MARRIAGES IS

'LOVE - AT FIRST - SIGHT' - MY

TRUE - BIRTH - 1964 - WOOD -

DRAGON - PASSIONATE YES -

ABOUT - MARTIAL - ARTS - & -

COOKING - BAKING - BOYISH -

NOT - FEMININE - THAT's ME -

ANN MILLER MGM MUSICALS -

SEHUN - EXO - 12 APRIL - 1964 -

10:30P PH - REALLY - MAKATI -

NOT - MANILA - THE CAPITAL -

BIRTHSTONE - DIAMOND - AS -

THAT - WEIRDO - PHILIPPINE -

FAMILY - WERE - PLANNING -

MAY - BIRTH - CERTIFICATE -

BORN - 8A PH - REPULSIVE -

WAITING - NOW - 'AMAZON'

[maitaitiu]

does anyone even remember this lot

[franciumkiichi]

@floofeon

this is a little late in the day but hey!! happy birthday!!! i drew a sweetie!!

[shwazzberryswriting]

Welcome to the NCT Teahouse Series!

In celebration of 200 followers I'm opening my Asks for fics I want to write for an Edo Era Teahouse Universe!

Starting today (17 March) my Asks will be open for fic requests for this AU (deadline date: March 31, 2022 *submissions will not be accepted after March*)! Fill out the form and I will write you a short fic (expected to be anywhere between 500 - 5k words per fic) with the scenario you want!

Warning: *Minors DNI* *While I will try my best, I want to apologize ahead of time if my AU isn't period accurate, I will be taking a lot of creative freedom given that it's an AU. DNI if you don't like the AU as mostly background and setup aesthetics*

How to participate: 1. Pick 1 (or more) of the NCT Teaboys from the list and I will write a smut piece *The personality pieces are for inspo and for fun; if you want something different for the guys' personalities in your fantasy (IE. Yuta is a samurai and Y/N works in the Teahouse) don’t hesitate to let me know in your request!*

2. Optional: Add in any details you want… IE. -Teaboy Dom or Sub or Switch? -Gender of OC/[Y/N] -plot details? -kinks? -anything else at all (within my regular request rules) ➡️💚

Pick your NCT Teaboy (or more if you can afford it):

~Sorry I couldn't add all 23 members; it was hard to choose who to put into this AU~

Seo Young Ho (Johnny): The most skilled Teaboy in the House, Young Ho often prepares his tea ceremonies in a secluded hut in the woods due to the noise complaints from patrons early in his career. Won’t you spend a night in the woods with this strapping Teaboy?

Lee Taeyong: Captivating with his dancing and shamisen playing skills, Taeyong is highly in demand. That won’t stop this enthusiastic Teaboy from giving you the most satisfying tea ceremony of your life…

Nakamoto Yuta: The Mysterious Teaboy might pour you the best cup of tea in your life…or he might be slipping you poison. Will you take the risk on the Teaboy no one knows anything about?

Qian Kun: The Gentle Tea Pourer has steady hands and a sweet voice. Smooth and complex like his tea, his skills will soothe your pains away…

Kim Doyoung: Well versed in all levels of acting, singing, dancing and tea skills, Doyoung will give you everything you want, and more…

Chittaphon Leechaiyapornkul: Ten, THE Ten. The most celebrated kabuki actor from the Teahouse has made a special visit to see the most special customer of all, you. You’ve just been granted access to his exclusive talents…

Jeong Yun-o: The Clumsy Teaboy’s hands will likely ruin your tea, but you’ll forget the imperfection when Jaehyun's hands work better on you…

Dong Sicheng (Winwin): The new Teaboy is a nervous wreck, but his earnest effort is charming. Once alone for the evening, Sicheng reveals a more assertive side in his tea ceremony…

Kim Jungwoo: Jungwoo provides the best company in his tea ceremonies. The Enthusiastic Teaboy will let you live out any and all of your wildest dreams…

Wong Kun-Hang (Hendery): The Unconventional Teaboy who can make you laugh provides you with relaxed company. His tea ceremonies can go anywhere from sweet and easy-going to extremely wild and…unconventional.

Lee Jeno: The Sweet Teaboy who lights the world with his smile! When you’re alone, his ceremonies are everything you want. Jeno lives to please you!

Na Jaemin: Attentive, generous, caring…Jaemin is the perfect Teaboy. When you finally make it into his busy schedule, The Adoring Teaboy will make all your dreams and wishes become reality…

Osaki Shotaro: The Teahouse’s Graceful Dancer enthralls you. Shotaro provides a comforting tea ceremony with his sweet face and soft voice. He’ll show you all sides to him if you’ll just stay with him for the night…

Have you chosen your Teaboy? Click (to send in request)➡️🍵

[wooyoungsblackhair]

Fandoms and Characters I Write For

This list will be updated in the future as I watch movies and shows I like and as I start stanning new kpop idols/groups, also please feel free to ask for a character/kpop idol I don’t write about, maybe I can come up with something, also feel free to recommend shows and movies for me to watch as well as kpop idols/groups to stan.

The Hunger Games

Peeta

Gale

Finnick

Cato

Divergent

Four/Tobias Eaton

Eric 

Peter

Will

The Maze Runner

Minho

Newt

Thomas 

Gally

Teen Wolf

Stiles Stilinski

Void Stiles

Scott McCall

Isaac Lahey

Theo Raeken

Liam Dunbar

Derek Hale

Peter Hale

Nolan Holloway

Aiden

The 100

Bellamy Blake

John Murphy

Finn Collins

Jasper Jordan

Monty Green

Jordan Green

Lincoln kom Trikru

Roan kom Azgeda

Harry Potter

Golden Trio Era

Draco Malfoy

Harry Potter

Ron Weasley

Fred Weasley

George Weasley

Charlie Weasley

Bill Weasley

Cedric Diggory

Neville Longbottom

Dean Thomas

Seamus Finnigan

Oliver Wood

Viktor Krum

Blaise Zabini

Marauders Era

Remus Lupin

Sirius Black

James Potter 

Peter Pettigrew 

Lucius Malfoy 

Severus Snape

Extra

Tom Riddle

Outer Banks

John B

JJ

Pope

Rafe 

Topper

Shadowhunters

Alec Lightwood

Jace Wayland

Raphael Santiago

Simon Lewis

Magnus Bane

Sebastian Verlac

Meliorn

Stranger Things

Billy Hargrove

Jonathan Byers

Steve Harrington

Fantastic Beasts

Newt Scamander

Theseus Scamander

Credence Barebone

Stray Kids

Bang Chan

Lee Minho (Lee Know)

Seo Changbin

Hwang Hyunjin

Han Jisung (Han)

Lee Yongbok (Felix)

Kim Seungmin

Yang Jeongin (I.N)

ATEEZ

Park Seonghwa

Kim Hongjoong

Jeong Yunho

Kang Yeosang

Choi San

Song Mingi

Jung Wooyoung

Choi Jongho

Tomorrow x Together

Choi Yeonjun

Choi Soobin

Choi Beomgyu

Kang Taehyun

Kai Huening (Hueningkai)

ENHYPEN

Lee Heeseung

Park Jong Seong (Jay)

Shim Jae Yun (Jake)

Park Sunghoon

Kim Sunoo

Yang Jungwon

Nishimura Riki (Ni-Ki)

The Boyz

Lee Sangyeon

Bae Joon Young (Jacob)

Kim Younghoon

Lee Jaehyun (Hyunjae)

Lee Juyeon

Moon Hyung Seo (Kevin)

Choi Chanhee (New)

Ji Changmin (Q)

Ju Haknyeon

Kim Sunwoo

Sohn Young Jae (Eric)

[milkbts]

♡ Disclaimer  ♡ Words: 3k

My Letterboxd - I rate movies  My TVTime - I rate K-dramas and any series that I watch.

♡ Context:

A Korean Odyssey (Hwayugi) is a romantic comedy & fantasy tv-series loosely based on the Chinese novel ‘Journey to the West’. 

♡ Main Cast:

Lee Seung-Gi as Son O-Gong, Cha Seung-Won as Woo Whee & Oh Yeon-Seo as Jin Sun-Mi

♡ Description:

The drama is about Son O-Gong and Jin Sun-Mi who meet under strange circumstances. Jin Sun-Mi has been able to see ghosts her entire life. When she was younger, she tried to help a demon king recover a precious artifact but instead, accidentally lets Son O-Gong out from his invisible house in the middle of the woods when he tricks her to do so as only a human can free him. Jin Sun-Mi, a naive child, becomes punished from this by being given the title “Samjang”. Jokes on both of them though as they meet again because of a deal they made long ago, but, you’ll have to see for yourself.  

♡ Ratings: IMDb (8.4/10), MyDramaList (8.4/10)  ♡ My Opinion: 9/10 -This drama was really good actually and I’d recommend it to anyone. (I started watching this with my friend as it’s our favourite pass time at sleepovers - so if you’re looking for a good time, watch this.) -Good acting -The story is good and I never found it slow or boring

♡ Context:

Age Of Youth (also known as Hello, My Twenties!) is a coming of age and romance drama. 

♡ Main Cast:

Season 1 - Han Ye-Ri as Yoon Jin-Myung, Han Seung-Yeon as Jung Ye-Eun, Park Eun-Bin as Song Ji-Won, Ryu Hwa-Young as Kang Yi-Na & Park Hye-Soo as Yoo Eun-Jae

Season 2 -  Han Ye-Ri as Yoon Jin-Myung, Han Seung-Yeon as Jung Ye-Eun, Park Eun-Bin as Song Ji-Won, Ryu Hwa-Young as Kang Yi-Na (only for special appearance), Ji-Woo as Yoo Eun-Jae & Choi A-Ra as Jo Eun

♡ Description:

Age Of Youth is about five female housemates who live together at the Belle Epoque. While strangers at first, they are able to bond and connect over the traumas they experienced while growing up and face challenges together. There are two seasons and some character changes in the second season.

♡ Ratings: IMBd (8.3/10), MyDramaList (8.8/10)

♡ My Opinion: 7/10 -I did really like Age of Youth and I think it’s a good drama for you to start watching if you are new to dramas.  -I give this drama a 7 out of 10, only because I’ve seen better ones suited towards my tastes. -Good actors but annoying they changed so much

♡ Context:

Black is a romance, thriller, fantasy, & comedy K-drama. 

♡ Main Cast:

Song Seung-Heon as Black & Han Moo-Gang & Go Ara as Kang Ha-Ram

♡ Description:

Black is the story of a Grim Reaper who is ordered to track down his partner who escaped to the mortal realm. In the process of this, he meets Kang Ha-Ram who can see the shadows of death despite being a mortal woman. This complicates things especially after he finds a case from 20 years ago and falls in love with Ha-Ram in the process. Supernatural rules against involvement in human affairs were meant to be broken, right?

♡ Ratings: IMBd (8.2/10), MyDramaList (8.3/10)

♡ My Opinion: 9/10 -One of my favourite K-Drama’s and I highly recommend this to anyone. -It gets a bit dark at times though so I suggest having a light comedy to watch afterward. -Good actors and they have nice chemistry in my opinion -Story is easy to follow

♡ Context:

Blood is a rom-com, action & suspense K-drama. 

♡ Main Cast:

Ahn Jae-Hyeon as Park Ji-Sang, Ku Hye-Sun as Yoo Ri-Ta & Ji Jin-Hee as Lee Jae-Wook

♡ Description:

Park Ji Sang is a doctor who works in the best cancer research hospital in the country. He is a great doctor because of his knowledge of the human anatomy and he’s a vampire... Despite him seeming cold and unfeeling, he has a soft heart and has experienced the inner pain of wanting to be close with people but without knowing how. He has very high morals and believes highly in the sanctity of human life so he suppresses his thirst for blood to save human lives; Unfortunately, he isn’t the only vampire and not all of them agree in his way of thinking. Among his colleagues is Yoo Ri Ta, a hotshot physician who entered medical school at the age of only 17 while simultaneously being the niece of the chairman.

♡ Ratings: IMBd (7.1/10), MyDramaList (7.5/10) 

♡ My Opinion: 8/10 -It took me a while to finish this drama but I lose interest quite easily so it isn’t anything to do with the quality of this drama. -My original interest in this drama came from the actress Ku Hye-sun as she was one of the main characters in Boys Over Flowers (next review). -The chemistry between the main actors, Ku Hye-sun and Ahn Jae-Hyun is really good (and they’re married in real life!). -This drama handles romance and everything pretty well however if you’re looking for a drama with a lot of fangirl moments then I suggest something else -(but this did have some good romance moments).

♡ Context:

Boys Over Flowers is a romance & a very, very dramatic drama.

♡ Main Cast:

Lee Min-Ho as Koo Jun-Pyo, Ku Hye-Seon as Geum Jan-Di, Kim Hyun-Joong as Yun Ji-Hu, Kim Beom as So Lee-Jeong & Kim Jun as Song Woo-Bin.

♡ Description:

At a famous high school for the incredibly rich, this love story is focussed on Geum Jan-di and the members of F4 - a gang of 4 handsome and rich men lead by Gu/Koo Jun-pyo. Jan-di is a poor girl with a poor family. She gets rewarded for a good deed and gets the chance to attend this high school. Here, she meets the infamous F4 group and is joined by Jun-pyo who is a spoiled heir to world-leading conglomerate ‘Shinwa’. Their love story travels from Seoul to New Caledonia to even Macau.

♡ Ratings: IMBd (8.1/10), MyDramaList (8/10)

♡ My Opinion: 8/10 -My friend and I watched this drama together as it’s said to be the OG K-drama, it’s like the orientation to the world of Korean Dramas.  -Many reviews hated it but this drama was fun to scream at when the characters made poor decisions -This made me cry (not surprising as a lot of these have made me cry) but this one is the most memorable to me because of the good times I had watching it; so I recommend this drama to anyone who firsts asks me for K-drama recs.   -Starts off slow but once you get into it you’ll have the time of your life.

♡ Context: 

Click Your Heart is a mini-series and romance drama.

♡ Main Cast: 

Kwon Mi Na as Mina, Baek Ju Ho as Ju Ho, Kang Cha Ni as Cha Ni, Kim Ro Woon as Ro Woon & Lee Da Won as Lee Da Won.

♡ Description:

Mina is a high-school student who must choose between an athlete, an ‘intellectual’, a ‘loner’ and a dancer. The episodes set these meetings up and you can click an episode that follows on from that - the episode you click is a different guy that she can choose, so you can literally Click Your Heart.

♡ Ratings: IMDb (6.6/10), MyDramaList (7.4/10)

♡ My Opinion: 6/10  -Good if you wanna experience what a k-drama is like -Too short for me and I prefer normal dramas -Quick to watch though -The acting wasn’t that bad

♡ Context:

Dream Knight is a romance/fantasy drama which centers around friendship.

♡ Main Cast:

Song Ha Yoon as Joo In Hyung & Got 7 - JB (himself), Mark (himself), Park Jin Young (himself), Jackson Wang (himself), BamBam (himself), Kim Yu Gyeom (himself) & Choi Young Jae (himself).

♡ Description:

A young girl called Joo In Hyung who suffers from her past has her life turned around when she unexpectedly meets a group of mysterious men.

♡ Ratings: IMDb (6.8/10), MyDramaList (7.5/10)

♡ My Opinion: 6/10  -Same as Click Your Heart to me honestly -It’s more of a friendship drama and a coming of age drama in my opinion -The acting isn’t too bad -Good for a quick watch & if you are just starting watching dramas and don’t know what genre you like yet 

♡ Context:

Good Morning Call is a Japanese Drama based on the manga series “Guddo Moningu Koru” by Yue Takasuka. Good Morning Call is a romance, friendship, and coming of age drama.

♡ Main Cast:

Fukuhara Haruka as Yoshikawa Nao & Shiraishi Shunya as Uehara Hisashi

♡ Description:

A young girl called Nao decides to stay behind and live by herself when her parents leave to inherit her grandfather’s farm in the countryside. When she moves into her new apartment, she meets Uehara, a popular- super hot boy who goes to the same school as her. They realize they have both rented the same apartment and when they go to the company it’s unexpectedly closed down and the rent has gone up dramatically. Nao and Uehara decide to live together as flatmates so neither of them has to go home.

♡ Ratings: IMDb (7.9/10), MyDramaList (7.8/10)

♡ My Opinion: 9/10 -One of the first dramas I watched and I really loved it -It’s dramatic, romantic and both actors have good chemistry. -There are now 2 seasons on Netflix & the second season didn’t disappoint. -It had fangirling worthy moments and moments to make you really feel for the characters. -WatCh tHiS 

♡ Context:

Mischievous Kiss: Love in Tokyo is based on the manga Itazura Na Kiss by Kaoru Tada. Mischievous Kiss is a romantic comedy Japanese drama.

♡ Main Cast:

Yahagi Honoka as Aihara Kotoko, Furukawa Yuki as Irie Naoki & Yamada Yuki as Ikezawa Kinnosuke

♡ Description:

At a high school entrance ceremony, Kotoko falls in love with Naoki whilst he gives a speech. She decides to confess her feelings via love letter. Unfortunately Naoki - a popular boy everyone is in-love with - turns her down saying “I don’t like dumb women.” One day Kotoko’s house is completely damaged by a meteorite and the house will not be re-built for a while, Kotoko’s dad decides to stay with a friend who happens to be Naoki’s father...

♡ Ratings: IMDb (7.9/10), MyDramaList (8.1/10)

♡ My Opinion: 8/10 -One of the first dramas I watched -It has 2 seasons and I liked it because of the build-up in a romance between both characters -Naoki’s character is cold which is literally my favourite kind because I know he's a softie -Kotoko and Naoki have good chemistry & the acting was very good in my opinion -The story was NEVER boring for me, the writers had really fun ways to make the story go along so I applaud them for that & recommend this drama (it’s very dramatic, VERY).

♡ Context: Noble, My Love is a romantic comedy K-Drama.

♡ Main Cast: 

Sung Hoon as Lee Kang Hoon & Kim Jae Kyung as Cha Yoon Seo

♡ Description: 

Kang Hoon is the CEO of the world’s largest company ‘D.O.L’. One day, he is kidnapped and escapes from his kidnappers but is badly injured. Luckily, he passes out in front of an animal hospital. Yeon Seo (veterinarian) finds him and attends to his wounds.

♡ Ratings: IMDb (7.1/10), MyDramaList (7.9/10)

♡ My Opinion: 7/10 -Most k-dramas have something dark going on behind the love that happens but this drama doesn’t -Many reviews I read were against this drama but my friend and I adored it because of how simple yet entertaining the story-line was. -It has good fluff moments and is good if you don’t like dark subjects in your Korean dramas or tv in general -A good drama to watch after an intense one :)

♡ Context:

Oh My Ghostess is a romantic comedy with supernatural elements including the food genre.

♡ Main Cast:

Park Bo Young as Na Bong Soon, Kim Seul Gi as Shin Sun Ae, Jo Jung Suk as Kang Seon Woo & Im Joo Hwan as Choi Seong Jae

♡ Description:

Bong-sun is a shy young woman who is possessed by a confident ghost of a lustful virgin. Bong-sun works as an assistant and has a crush on her boss. She makes a deal with the ghost as her grandmother was a shaman so from a young age she has been able to see ghosts. They agree that the ghost will help Bong-sun get her boss’s attention if she helps her pass over to the after-life before her time runs out.

♡ Ratings: IMDb (8.2/10), MyDramaList (/10)

♡ My Opinion: 8/10 -Was difficult for me to get into but I thoroughly enjoyed it -It has cute moments & the acting is great -Basically just watch this 

♡ Context:

One More Time is a romance and friendship drama (also known as The Day After We Parted)

♡ Main Cast: 

L as Yoo Tak & Yoon So Hee as Da In

♡ Description:

Yoo Tak is the leader and vocalist of an indie band called One More Time. He’s been maintaining the band for around 10 years but they haven’t acheived their dreams yet and aren’t getting any younger. Yoo Tak begins to take for granted his friends and girlfriend but a young grim reaper has something to say about that. She puts him in a time loop and he has to continue living the same day over and over again until he learns what is really important.

♡ Ratings: IMDb (6.8/10), MyDramaList (7.7/10)

♡ My Opinion: 8/10 -I liked the angst and sadness in this and the life lessons in it -The acting was really good -It isn’t boring and it’s quick to watch -The ending confused me but I liked the deeper meaning :)

♡ Context: 

Strong Woman Do Bong Soon (also known as Strong Girl Bong Soon) is an action, comedy, romance & supernatural k-drama

♡ Main Cast: 

Park Bo Young as Do Bong Soon, Park Hyungsik as Ahn Min Hyuk & Ji Soo as In Gook Doo

♡ Description: 

Bong Soon is a young woman who is kind, honest and has superhuman strength... Her family has been gifted Herculean strength from birth to be used for the greater good. If the power is abused it is taken away. While standing up for herself to a group of gang members, Ahn Min Hyuk - who has never trusted the police - witnesses the entire ordeal and asks Bong Soon to be his bodyguard. She agrees and the two fall in love, but the world has different plans in mind for the pair.

♡ Ratings: IMDb (8.3/10), MyDramaList (8.8/10) 

♡ My Opinion: 9.5 -I like the chemistry between the actors in real life AND in the drama. They make a good team. -The balance between all the fluff and romance with the danger is really well done -This is one of my favourite K-drama's  -Watch this Drama if you want clear skin and a new love for yourself

♡ Context:

Switched is a Japanese supernatural and suspense drama

♡ Main Cast:

Tomita Miu as Umnie Zenko, Kiyohara Kaya as Kohinata Ayumi, Kamiyama Tomohiro as Mizumoto Koushirou & Shigeoka Daiki as Kaga Shunpei

♡ Description:

A suicidal teenage girl swaps bodies with a popular girl in her class - but she has no intention of switching back.

♡ Ratings: IMDb (7.2/10), MyDramaList (8.2/10)

♡ My Opinion: 7/10 -For a drama that isn't suited to my tastes, this one really impressed me. -The acting it takes to be able to pull off a successful bodyswap is extremely difficult and the actresses acting in this drama is immaculate. -This has a lot of angst, considering the suicide references, but is a good drama. -This J-Drama has only been given a 7 out of ten because of the plot (which is still great but not my type) but the acting I'd say is the best here.

♡ Context:

The Girl Who Sees Scents (also commonly referred to as The Girl Who Sees Smells & based on the webcomic 'Naemsaereul Boneun Sonyeo) is a romantic comedy with supernatural genres.

♡ Main Cast:

Park Yoo Chun as Choi Moo Gak, Shin Se Kyung as Oh Cho Rim & Nam Goong Min as Kwon Jae Hee

♡ Description:

Officer Choi Moo Gak lost his younger sister to a serial killer and lost his ability to taste, smell and feel any pain whatsoever. Oh Cho Rim, the only witness to the murder case, lost her memory but gained the ability to see smells.

♡ Ratings: IMDb (7.3/10), MyDramaList (8.1/10)

♡ My Opinion: 9/10 -Damn actor Nam Goong Min is hot -The serial killer is also a great fucking idea -The acting is decent and the actors have great fluffy moments -This drama was so addicting for me which is why it has such a high rating -I also really appreciated the ending, something that doesn't usually happen with me and dramas. -This is a must watch

♡ Context:

The Great Seducer (also known as Tempted) is a friendship and romance Melo-k-drama

♡ Main Cast:

Woo Do Hwan as Kwon Si Hyun, Joy as Eun Tae Hee, Moon Ga Young as Choi Soo Hi & Kim Min Jae as Lee Se Joo

♡ Description:

The Great Seducer depicts rich young men and women in their twenties who discover their feelings of love for one another while playing a dangerous bet involved with love. Kwon Si Hyun makes a bet with his friends that he can seduce Eun Tae Hee, who believes that people who are swayed too easily by love are stupid. After Tae Hee meets Si Hyun, her view of love changes and Si Hyun's heart becomes less ice-cold. Secrets become hard to keep as Si Hyun falls deeper in love with Eun Tae Hee.

♡ Ratings: IMDb (7.1/10), MyDramaList (7.6/10)

♡ My Opinion: 10/10 -I LOVE THIS DRAMA SO MUCH OKAY -MY FRIEND AND I STARTED THIS TOGETHER I LOVED IT -THE ACTING IS SO GOOD AND I LOVE WOO DO HWAN AND JOY (red velvet) -Joy's acting has improved a lot and her character is lovely and relatable -The drama is literally my aesthetic and the toxic friend groups and angst of this drama is what I thrive off -Watch. This. You. Cowards. -I could write essays upon essays about this, but tumblr won't allow that...

[willowgust]

Singing On the Fence

~Music~

The graceful sweep of pale trees and elven towers stood beside the sun’s half-hidden disk. Motionless air stewed in the aroma of warm ocean salt and algae. 

Seo-yun’s glazed stare drifted with the rapid glimmer of the sea. His eyes were lost on the pink horizon. They were tired. Blank. And his paws were empty. Not even a box of lures sat at his side.

He didn’t seem to notice the blase-faced gunslinger strutting closer, or the footsteps creaking the wharf’s shallow planks. Oshiban took a casual swig from his cask of scotch and grinned down at him. “Hey hey, if it isn’t my favorite wharf bum!” His nose crinkled at Seo-yun’s familiar fish stench, apparently tolerating it. “I thought you and Naggy McBonenag were all fixed up? I asked if you struck back out with the Tarts and heard you were a no-show. Weren’t you going to--woah,” he stopped. “Woah. Back up. This can’t be what I’m seeing, right?” Oshiban veered his head, searching every feasible angle of the water. All he saw was a pair of fuzzy feet dangling over the wharf. “You’re not fishing? The hell’s the matter, you sick or something?”

Seo-yun said nothing.

“...Oh,” he sighed, rolling his eyes with a jaded frown. “Let me guess. You heard about the barbecued Kaldorei-kabobs? Is that 500 gold to Mr. Il’vineen or am I way off?”

A low huff of air fled his nose.

“Listen, I hate those freakin’ fairy snobs, but even I think that was pretty messed up. Not to mention that World Tree’s literally toast and that’ll probably bite us all in the ass later. But hey. Only one crazy bitch made that call. No one else has changed, yanno? I mean, okay. Not even Saurfang stopped her, but just goes to show. We’re all out for our own backs. That’s how it is.”

The pandaren finally spared him a side-glance.

“There he is. Here, you need this more than me.” He offered his flask.

Seo-yun hesitated... then grabbed it and threw back his head. Glug, glug, glug, glug, glug-- 

Oshiban snatched it back, “Hey, that’s enough! That 12-year stuff isn’t cheap. And you know you’re not supposed to chug it like that, right?”

With his paw still in mid-air, his eyes bubbled sadly at its sudden lack of booze.

“...Fuck. That’s just not fair. How does a guy this shabby figure out a way to look that adorable? Fine, take it.”

--Grab! Glug, glug, glug, glug... Seo-yun pulled his head upright once he’d drained the cask of its last drop. He seemed a little more content. Somewhat.

“Look,” Oshiban slid to a seat beside him. “That edge queen’s always been bad news. Nothing has to be different. It’s not like you’ve ever actually joined the Horde army and have to stand by all the Warchief’s shitty decisions. You can still go out and be our resident lawn sprinkler, rock some piano, make a shaman-y slip-and-slide for the kids... I mean, yanno. August gets pretty bad.”

“...Noodles ‘n’ seafood.”

He blinked at him, startled to hear his voice. “Uhhh. You asking to order out? If that’s the case my vote is on Troll cajun. I had noodles last night.”

Seo-yun handed back Oshiban’s flask and finally turned to face him. His eyes brimmed with a sudden heartfelt tension. “Noodles ‘n’ seafood. Ya wanna know what got me into th’ Horde? That’s it. Left Northrend, reunited with my ol’ family, saved ‘em from the Sha, and didn’t know where to go. So I started that Tuskarr-Pandaren restaurant ya liked. Needed a venue. Was hard to find space after everyone ‘n’ their gramma was inspired to cook 'cause o’ Pandaria. Stormwind, full. Darnassus, full. Ironforge, full. Orgrimmar, full. Undercity made me barf. Silvermoon had a space. Set up shop, kicked ass, then went outta business after a year ‘cause the guy who took over cut too many corners. Fished, sailed around, and joined the Tarts. That’s it. That’s how I joined the Horde. Inspired yet?”

Oshiban stared at him in awe, his jaw unashamedly ajar, as Seo-yun actually continued making a long-winded speech. 

“Family’s everythin’ to me. But my family’s never been the Horde. Thought th’ feud between Alliance and Horde was dumb since day one. Been as neutral as they come. But I’ve been throwin’ myself around battlefields just tryin’ to make sure none o’ my friends die. I’m tired! And hungry! Well, I’m always hungry, but I’m tired! Now everyone wants me fightin’ again because the Alliance are angry that the Horde attacked because they’re angry the Alliance attacked because the Horde did this and the Alliance did-- it’s so confusing!!” his graveled voice cried, the rims of his eyes reddening with tears. “I can’t keep track an’ I don’t care! Got called a hypocrite ‘cause I’m not ‘treatin’ the Horde like my family,’ but the Horde never were. Got friends in all kinds o’ factions! All I wanna care about is what to do fer my next show and whether ‘r not my friends ‘n’ family’re okay. Those’re my people. Are a bunch of ‘em suddenly not if I don’t wanna fight fer the Horde? Why can’t I stick by them without havin’ to die fer a war that even I know is stupid?!”

Once the initial shock had passed, Oshiban’s gaze fell to the lapping tide. A small, grim smile tugged his mouth. He looked back up. “Hey. Uh. I’m really bad at this advice thing, but I do have something to say. Seo-yun, you’re naive, slow, have rose-colored glasses super-glued to your fur, and you’re so stupid you make kobolds look like gnomish physics professors. But you’re among the few people I’ve ever met that I actually like. You know why?”

Seo-yun sniffled and wiped his nose.

“You have something that, like, 98% of people on this rock either don’t have, or lie about having. You have a heart of actual gold. You’re like... one of those small boys in Winter’s Veil specials that Greatfather Winter sits on his lap before he says ‘once upon a time.’ Or a giant puppy. You don’t have a cruel or deceitful bone in your body and you’re too dumb to manipulate anyone. You’re insanely loyal to people who don’t deserve it, and that’s exactly why they call you a hypocrite. They know the loyalty you have to your families, and they wish they had the balls. Projection’s a bitch.” Oshiban scoffed, “Hell... even I’m jealous. But that’s probably because, honestly? It’d be nice to have a family at all. I learned kinda quick that life’s too full of back-stabbing bastards to really have anything like that.” He shrugged, “That’s life.

“Anyway, I sorta... I wish I could protect that wildly misguided innocence you have. I wish I could stop your heart from growing up. If there were more of you I’d be out of a job, but it’s kinda nice to know that people like you exist. So if you don’t wanna fight for the Horde because the Horde isn’t your family? Then don’t. Don’t listen to those assbags. Grab your keyboard and sing on your neutral fence. Throw waterpark buckets all over people as a Moa’ki guy who’s just keeping his friends alive, not a Horde guy. Who cares? You and me are gonna be rolling in it anyway.”

Confused, Seo-yun knitted his forehead, waiting for him to elaborate.

“I’m gonna make big bucks takin’ out bad guys for the Horde. You, however, won’t just have plenty of work as a healer. You’re the piano guy. That’s why people are gonna need you more than they’ll ever need me.” Oshiban smiled.

Seo-yun’s eyes glinted with a touched warmth. He returned it. “Thanks, man.” With a leathery shuffle against wood, he turned back to admire the sea.

“So uh, you know I got lots of contacts in the spa industry you’re... you’re sure you don’t wanna do anything about that fish smell situation?”

Seo-yun snorted wryly. “Tell ‘em ‘Good luck.’”

[small-powerful-deeds-blog]

 You are invited to the First Annual,

                                        Green & Gold Gala

                                                     Hosted by Light of Quel’Thalas

  Please join us on Saturday, March 25th, as the chime tolls six in the evening for an elegant charity event! All are invited and urged to enjoy this night in the beauty of nature and the elegance of culture. 

  Dress code is black tie, in the theme of gold and green! 

  Wine provided by Empyrean Imports! A special treat, entertainment by the Succulent Tart’s own Seo-yun Whalecarver! A ‘Skills Auction’ and raffle! Refreshments, hors d'oeuvres will be available as well as live music for dancing!

  Here at Light of Quel’Thalas we seek to reach into the dark places of this world touched by war and shed Light on those in the most need. Please help us by attending our first fundraising event!

Come enjoy an evening of frivolity and light hearted fun, and maybe give a little to those less fortunate as well!

Date: Saturday, March 25th Time: 6:00pm Location: Saltheril’s Haven, Eversong Woods Contact: Lady Kaeli’andra Bloodvale ( @fire-and-diamonds )

          - @whalecarver - @safrona-shadowsun - @sybil-galeshatter -

OOC Info:

This is an open RP server event, welcoming to all of the Horde. Unfortunately, game mechanics make cross faction RP nearly impossible. 

The Guild is always looking for contacts and associates (this can be cross faction) so please feel free to boost, reblog or contact the guild leaders with both OOC and IC questions or ideas!

We would love to find an IC band, another performer and a caterer for this event! Anyone who is interested please contact Kaeli! 

Thank you!

[jesseneufeld]

Dear Mark: Iron Followup

Last week’s post on iron levels got a big response and garnered a ton of questions from you guys. Today, I’m going to clarify a few things and answer as many questions as I can. First, do iron and ferritin levels mean different things for men and women? If so, how do those differences manifest? What about premenopausal women vs postmenopausal women? Second, what do we make of the fact that ferritin is also increased in times of inflammation? Is there a way to distinguish between elevated ferritin caused by inflammation and elevated ferritin caused by high iron? Third, is desiccated liver a good option for liver haters? And finally, I share some exciting plague news.

Let’s go:

Emma wrote:

I’d love to see more info on iron levels as they relate to men and women differently. I recently had an iron infusion for low ferretin, not thinking much would change I actually experienced so many positive effects I didn’t even know were coming my way. I’m less cold, no more afternoon fatigue, less hair falling out, no more random palpitations, improved restless leg syndrome and the number one big change is it improved anxiety levels – in fact my anxiety is now gone. The last two are due to a connection between iron and dopamine. I learnt that children with mental health issues are often treated for low ferretin where possible, elevating levels to around 100 showing positive results (would love to see literature on this), for me my ferretin went from 20 to 130 and its changed my life, at 31 I haven’t felt this good in years. Yay iron!

That’s awesome to hear. Yes, it’s important to stress the very basic essentiality of iron. Without it, we truly cannot produce energy. And since energy is the currency for everything that happens in the body, an iron deficiency makes everything start to fall apart.

As for gender and iron, there’s a lot to discuss.

A good portion of women with hemochromatosis never actually express it phenotypically, meaning their lab tests don’t show evidence of dysregulated iron metabolism or storage. According to one study of hemochromatosis homozygotes (people who inherited the mutation from both of their parents), being a woman makes it 16x more likely that your hereditary hemochromatosis won’t actually present as iron overload.

Another study found that among mostly-age-matched men (42 years) and women (39 years) with hemochromatosis, 78% of the men had iron overload while just 36% of the women had it. Iron overload was defined as transferrin saturation over 52% combined with ferritin levels of 300 ng/mL for men and 200 ng/mL for women.

High iron levels are more of an issue for postmenopausal women than premenopausal women. The latter group regularly sheds blood through menstruation, and if anything, they’re at a higher risk of low iron. Plus, estrogen is a key regulator of iron metabolism. As menopause sets in and estrogen diminishes, that regulation suffers.

For instance:

In postmenopausal Korean women, high ferritin levels predict metabolic syndrome and subclinical atherosclerosis.

High ferritin predicts metabolic syndrome in postmenopausal but not premenopausal women.

In premenopausal Korean women, higher ferritin levels predict better bone mineral density; menopause nullifies this relationship.

Remember that ferritin is actually a measurable protein bound to iron, so testing a ferritin level is technically an indirect way to measure iron. Why is this important? Another characteristic of ferritin (the protein) is that it is an ACUTE PHASE REACTANT. This means that ferritin levels can fluctuate with illnesses and other inflammatory states in the body that drive up a ferritin value that is not related to an actual iron level fluctuation. Don’t get ferritin checked when you are sick with a cold or other illness.

This is a great point.

Ferritin is marker of long term iron storage, but it’s also an acute phase reactant that up regulates in response to inflammation or oxidative stress.

If you want to be really careful, you should get a HS-CRP test—that measures your overall inflammatory status. If CRP is elevated, ferritin can be elevated without saying anything about your iron status.

Come to think of it, if elevated ferritin can be a marker of inflammation and oxidative stress, the inflammation could be responsible for some of the negative health effects linked to high ferritin. Or, if having too much iron in the body can increase oxidative damage, it may be that high iron levels are increasing inflammation which in turn increases ferritin even further. Biology gets messy. Lots of feedback loops. However, the fact that many studies cited in the previous iron post that use blood donation to treat high ferritin have positive results indicates that for most people, ferritin can be, in most situations, an accurate estimation of your iron status.

To make sure it’s an iron problem, get a transferrin saturation test as well. That indicates the amount of iron you’re absorbing, with below 20% being low and over 45% being high. People with high ferritin and high transferrin saturation do have high iron levels. People whose ferritin is artificially enhanced by inflammation will have normal transferrin saturation levels.

I have one last question on this. You say “Don’t stop eating liver every week.” If you can’t stand the taste of liver, what do you think about taking liver capsules made from grass-fed New Zealand beef every day instead?

That’s a great option. Go for it.

People should generally aim for 4-8 ounces of fresh liver a week. Note the amount of desiccated liver in your capsules and multiply by 3 to get the fresh liver equivalent, then take enough each day (or all at once) to hit 4-8 ounces over the week. I hear good things about this one.

Mark, Thank you for your article on HH. I carry the gene but have been managing my iron levels through phlebotomies. I am full Keto, meat and all and have found my iron levels have not been effected by going Keto. Early detection is the key and ongoing monitoring. Bring on the plague!!!

You joke about that now, but there’s a startup that’s breeding heritage rat fleas that produce a mild strain of the plague that evades the attention of the immune system and proliferates throughout the body to keep iron levels in check without killing you. I’m an early investor, have a couple swarms installed in my condo, and (knock on wood) so far have avoided anything worse than a sore throat and maybe a mild open sore or two. There’s actually a big rift forming between the techs who want to keep the fleas heritage and those who want to go ahead with CRISPR and engineer them. One variant has had a deer tick gene inserted that adds an anesthetic compound to the flea’s saliva. That way you can have a personal swarm on you and never feel any bites or itches.

I’m not sure about CRISPR just yet, but I gotta say it’s pretty nice to be covered in fleas and not feel the bites. Time will tell.

Ok, I’m joking.

That’s it for today, folks. I hope I’ve answered some of your concerns, and if not, let me know down below. Thanks for reading!

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Want to make fat loss easier? Try the Definitive Guide for Troubleshooting Weight Loss for free here.

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References:

Lainé F, Jouannolle AM, Morcet J, et al. Phenotypic expression in detected C282Y homozygous women depends on body mass index. J Hepatol. 2005;43(6):1055-9.

Qian Y, Yin C, Chen Y, et al. Estrogen contributes to regulating iron metabolism through governing ferroportin signaling via an estrogen response element. Cell Signal. 2015;27(5):934-42.

Seo SK, Yun BH, Chon SJ, et al. Association of serum ferritin levels with metabolic syndrome and subclinical coronary atherosclerosis in postmenopausal Korean women. Clin Chim Acta. 2015;438:62-6.

Cho GJ, Shin JH, Yi KW, et al. Serum ferritin levels are associated with metabolic syndrome in postmenopausal women but not in premenopausal women. Menopause. 2011;18(10):1120-4.

Chon SJ, Choi YR, Roh YH, et al. Association between levels of serum ferritin and bone mineral density in Korean premenopausal and postmenopausal women: KNHANES 2008-2010. PLoS ONE. 2014;9(12):e114972.

The post Dear Mark: Iron Followup appeared first on Mark's Daily Apple.

Dear Mark: Iron Followup published first on https://drugaddictionsrehab.tumblr.com/

[cristinajourdanqp]

Dear Mark: Iron Followup

Last week’s post on iron levels got a big response and garnered a ton of questions from you guys. Today, I’m going to clarify a few things and answer as many questions as I can. First, do iron and ferritin levels mean different things for men and women? If so, how do those differences manifest? What about premenopausal women vs postmenopausal women? Second, what do we make of the fact that ferritin is also increased in times of inflammation? Is there a way to distinguish between elevated ferritin caused by inflammation and elevated ferritin caused by high iron? Third, is desiccated liver a good option for liver haters? And finally, I share some exciting plague news.

Let’s go:

Emma wrote:

I’d love to see more info on iron levels as they relate to men and women differently. I recently had an iron infusion for low ferretin, not thinking much would change I actually experienced so many positive effects I didn’t even know were coming my way. I’m less cold, no more afternoon fatigue, less hair falling out, no more random palpitations, improved restless leg syndrome and the number one big change is it improved anxiety levels – in fact my anxiety is now gone. The last two are due to a connection between iron and dopamine. I learnt that children with mental health issues are often treated for low ferretin where possible, elevating levels to around 100 showing positive results (would love to see literature on this), for me my ferretin went from 20 to 130 and its changed my life, at 31 I haven’t felt this good in years. Yay iron!

That’s awesome to hear. Yes, it’s important to stress the very basic essentiality of iron. Without it, we truly cannot produce energy. And since energy is the currency for everything that happens in the body, an iron deficiency makes everything start to fall apart.

As for gender and iron, there’s a lot to discuss.

A good portion of women with hemochromatosis never actually express it phenotypically, meaning their lab tests don’t show evidence of dysregulated iron metabolism or storage. According to one study of hemochromatosis homozygotes (people who inherited the mutation from both of their parents), being a woman makes it 16x more likely that your hereditary hemochromatosis won’t actually present as iron overload.

Another study found that among mostly-age-matched men (42 years) and women (39 years) with hemochromatosis, 78% of the men had iron overload while just 36% of the women had it. Iron overload was defined as transferrin saturation over 52% combined with ferritin levels of 300 ng/mL for men and 200 ng/mL for women.

High iron levels are more of an issue for postmenopausal women than premenopausal women. The latter group regularly sheds blood through menstruation, and if anything, they’re at a higher risk of low iron. Plus, estrogen is a key regulator of iron metabolism. As menopause sets in and estrogen diminishes, that regulation suffers.

For instance:

In postmenopausal Korean women, high ferritin levels predict metabolic syndrome and subclinical atherosclerosis.

High ferritin predicts metabolic syndrome in postmenopausal but not premenopausal women.

In premenopausal Korean women, higher ferritin levels predict better bone mineral density; menopause nullifies this relationship.

Remember that ferritin is actually a measurable protein bound to iron, so testing a ferritin level is technically an indirect way to measure iron. Why is this important? Another characteristic of ferritin (the protein) is that it is an ACUTE PHASE REACTANT. This means that ferritin levels can fluctuate with illnesses and other inflammatory states in the body that drive up a ferritin value that is not related to an actual iron level fluctuation. Don’t get ferritin checked when you are sick with a cold or other illness.

This is a great point.

Ferritin is marker of long term iron storage, but it’s also an acute phase reactant that up regulates in response to inflammation or oxidative stress.

If you want to be really careful, you should get a HS-CRP test—that measures your overall inflammatory status. If CRP is elevated, ferritin can be elevated without saying anything about your iron status.

Come to think of it, if elevated ferritin can be a marker of inflammation and oxidative stress, the inflammation could be responsible for some of the negative health effects linked to high ferritin. Or, if having too much iron in the body can increase oxidative damage, it may be that high iron levels are increasing inflammation which in turn increases ferritin even further. Biology gets messy. Lots of feedback loops. However, the fact that many studies cited in the previous iron post that use blood donation to treat high ferritin have positive results indicates that for most people, ferritin can be, in most situations, an accurate estimation of your iron status.

To make sure it’s an iron problem, get a transferrin saturation test as well. That indicates the amount of iron you’re absorbing, with below 20% being low and over 45% being high. People with high ferritin and high transferrin saturation do have high iron levels. People whose ferritin is artificially enhanced by inflammation will have normal transferrin saturation levels.

I have one last question on this. You say “Don’t stop eating liver every week.” If you can’t stand the taste of liver, what do you think about taking liver capsules made from grass-fed New Zealand beef every day instead?

That’s a great option. Go for it.

People should generally aim for 4-8 ounces of fresh liver a week. Note the amount of desiccated liver in your capsules and multiply by 3 to get the fresh liver equivalent, then take enough each day (or all at once) to hit 4-8 ounces over the week. I hear good things about this one.

Mark, Thank you for your article on HH. I carry the gene but have been managing my iron levels through phlebotomies. I am full Keto, meat and all and have found my iron levels have not been effected by going Keto. Early detection is the key and ongoing monitoring. Bring on the plague!!!

You joke about that now, but there’s a startup that’s breeding heritage rat fleas that produce a mild strain of the plague that evades the attention of the immune system and proliferates throughout the body to keep iron levels in check without killing you. I’m an early investor, have a couple swarms installed in my condo, and (knock on wood) so far have avoided anything worse than a sore throat and maybe a mild open sore or two. There’s actually a big rift forming between the techs who want to keep the fleas heritage and those who want to go ahead with CRISPR and engineer them. One variant has had a deer tick gene inserted that adds an anesthetic compound to the flea’s saliva. That way you can have a personal swarm on you and never feel any bites or itches.

I’m not sure about CRISPR just yet, but I gotta say it’s pretty nice to be covered in fleas and not feel the bites. Time will tell.

Ok, I’m joking.

That’s it for today, folks. I hope I’ve answered some of your concerns, and if not, let me know down below. Thanks for reading!

Want to make fat loss easier? Try the Definitive Guide for Troubleshooting Weight Loss for free here.

References:

Lainé F, Jouannolle AM, Morcet J, et al. Phenotypic expression in detected C282Y homozygous women depends on body mass index. J Hepatol. 2005;43(6):1055-9.

Qian Y, Yin C, Chen Y, et al. Estrogen contributes to regulating iron metabolism through governing ferroportin signaling via an estrogen response element. Cell Signal. 2015;27(5):934-42.

Seo SK, Yun BH, Chon SJ, et al. Association of serum ferritin levels with metabolic syndrome and subclinical coronary atherosclerosis in postmenopausal Korean women. Clin Chim Acta. 2015;438:62-6.

Cho GJ, Shin JH, Yi KW, et al. Serum ferritin levels are associated with metabolic syndrome in postmenopausal women but not in premenopausal women. Menopause. 2011;18(10):1120-4.

Chon SJ, Choi YR, Roh YH, et al. Association between levels of serum ferritin and bone mineral density in Korean premenopausal and postmenopausal women: KNHANES 2008-2010. PLoS ONE. 2014;9(12):e114972.

The post Dear Mark: Iron Followup appeared first on Mark's Daily Apple.

[maitaitiu]

it’s pride month so ive decided to draw one of my ocs every day (tho ive left a few blank so i can not break my arm)

so first up is seo-yun!! she’s the ultimate gamer girl,.. she plays the video game.,,.. she Kisses the girls

[milenasanchezmk]

Dear Mark: Iron Followup

Last week’s post on iron levels got a big response and garnered a ton of questions from you guys. Today, I’m going to clarify a few things and answer as many questions as I can. First, do iron and ferritin levels mean different things for men and women? If so, how do those differences manifest? What about premenopausal women vs postmenopausal women? Second, what do we make of the fact that ferritin is also increased in times of inflammation? Is there a way to distinguish between elevated ferritin caused by inflammation and elevated ferritin caused by high iron? Third, is desiccated liver a good option for liver haters? And finally, I share some exciting plague news.

Let’s go:

Emma wrote:

I’d love to see more info on iron levels as they relate to men and women differently. I recently had an iron infusion for low ferretin, not thinking much would change I actually experienced so many positive effects I didn’t even know were coming my way. I’m less cold, no more afternoon fatigue, less hair falling out, no more random palpitations, improved restless leg syndrome and the number one big change is it improved anxiety levels – in fact my anxiety is now gone. The last two are due to a connection between iron and dopamine. I learnt that children with mental health issues are often treated for low ferretin where possible, elevating levels to around 100 showing positive results (would love to see literature on this), for me my ferretin went from 20 to 130 and its changed my life, at 31 I haven’t felt this good in years. Yay iron!

That’s awesome to hear. Yes, it’s important to stress the very basic essentiality of iron. Without it, we truly cannot produce energy. And since energy is the currency for everything that happens in the body, an iron deficiency makes everything start to fall apart.

As for gender and iron, there’s a lot to discuss.

A good portion of women with hemochromatosis never actually express it phenotypically, meaning their lab tests don’t show evidence of dysregulated iron metabolism or storage. According to one study of hemochromatosis homozygotes (people who inherited the mutation from both of their parents), being a woman makes it 16x more likely that your hereditary hemochromatosis won’t actually present as iron overload.

Another study found that among mostly-age-matched men (42 years) and women (39 years) with hemochromatosis, 78% of the men had iron overload while just 36% of the women had it. Iron overload was defined as transferrin saturation over 52% combined with ferritin levels of 300 ng/mL for men and 200 ng/mL for women.

High iron levels are more of an issue for postmenopausal women than premenopausal women. The latter group regularly sheds blood through menstruation, and if anything, they’re at a higher risk of low iron. Plus, estrogen is a key regulator of iron metabolism. As menopause sets in and estrogen diminishes, that regulation suffers.

For instance:

In postmenopausal Korean women, high ferritin levels predict metabolic syndrome and subclinical atherosclerosis.

High ferritin predicts metabolic syndrome in postmenopausal but not premenopausal women.

In premenopausal Korean women, higher ferritin levels predict better bone mineral density; menopause nullifies this relationship.

Remember that ferritin is actually a measurable protein bound to iron, so testing a ferritin level is technically an indirect way to measure iron. Why is this important? Another characteristic of ferritin (the protein) is that it is an ACUTE PHASE REACTANT. This means that ferritin levels can fluctuate with illnesses and other inflammatory states in the body that drive up a ferritin value that is not related to an actual iron level fluctuation. Don’t get ferritin checked when you are sick with a cold or other illness.

This is a great point.

Ferritin is marker of long term iron storage, but it’s also an acute phase reactant that up regulates in response to inflammation or oxidative stress.

If you want to be really careful, you should get a HS-CRP test—that measures your overall inflammatory status. If CRP is elevated, ferritin can be elevated without saying anything about your iron status.

Come to think of it, if elevated ferritin can be a marker of inflammation and oxidative stress, the inflammation could be responsible for some of the negative health effects linked to high ferritin. Or, if having too much iron in the body can increase oxidative damage, it may be that high iron levels are increasing inflammation which in turn increases ferritin even further. Biology gets messy. Lots of feedback loops. However, the fact that many studies cited in the previous iron post that use blood donation to treat high ferritin have positive results indicates that for most people, ferritin can be, in most situations, an accurate estimation of your iron status.

To make sure it’s an iron problem, get a transferrin saturation test as well. That indicates the amount of iron you’re absorbing, with below 20% being low and over 45% being high. People with high ferritin and high transferrin saturation do have high iron levels. People whose ferritin is artificially enhanced by inflammation will have normal transferrin saturation levels.

I have one last question on this. You say “Don’t stop eating liver every week.” If you can’t stand the taste of liver, what do you think about taking liver capsules made from grass-fed New Zealand beef every day instead?

That’s a great option. Go for it.

People should generally aim for 4-8 ounces of fresh liver a week. Note the amount of desiccated liver in your capsules and multiply by 3 to get the fresh liver equivalent, then take enough each day (or all at once) to hit 4-8 ounces over the week. I hear good things about this one.

Mark, Thank you for your article on HH. I carry the gene but have been managing my iron levels through phlebotomies. I am full Keto, meat and all and have found my iron levels have not been effected by going Keto. Early detection is the key and ongoing monitoring. Bring on the plague!!!

You joke about that now, but there’s a startup that’s breeding heritage rat fleas that produce a mild strain of the plague that evades the attention of the immune system and proliferates throughout the body to keep iron levels in check without killing you. I’m an early investor, have a couple swarms installed in my condo, and (knock on wood) so far have avoided anything worse than a sore throat and maybe a mild open sore or two. There’s actually a big rift forming between the techs who want to keep the fleas heritage and those who want to go ahead with CRISPR and engineer them. One variant has had a deer tick gene inserted that adds an anesthetic compound to the flea’s saliva. That way you can have a personal swarm on you and never feel any bites or itches.

I’m not sure about CRISPR just yet, but I gotta say it’s pretty nice to be covered in fleas and not feel the bites. Time will tell.

Ok, I’m joking.

That’s it for today, folks. I hope I’ve answered some of your concerns, and if not, let me know down below. Thanks for reading!

Want to make fat loss easier? Try the Definitive Guide for Troubleshooting Weight Loss for free here.

References:

Lainé F, Jouannolle AM, Morcet J, et al. Phenotypic expression in detected C282Y homozygous women depends on body mass index. J Hepatol. 2005;43(6):1055-9.

Qian Y, Yin C, Chen Y, et al. Estrogen contributes to regulating iron metabolism through governing ferroportin signaling via an estrogen response element. Cell Signal. 2015;27(5):934-42.

Seo SK, Yun BH, Chon SJ, et al. Association of serum ferritin levels with metabolic syndrome and subclinical coronary atherosclerosis in postmenopausal Korean women. Clin Chim Acta. 2015;438:62-6.

Cho GJ, Shin JH, Yi KW, et al. Serum ferritin levels are associated with metabolic syndrome in postmenopausal women but not in premenopausal women. Menopause. 2011;18(10):1120-4.

Chon SJ, Choi YR, Roh YH, et al. Association between levels of serum ferritin and bone mineral density in Korean premenopausal and postmenopausal women: KNHANES 2008-2010. PLoS ONE. 2014;9(12):e114972.

The post Dear Mark: Iron Followup appeared first on Mark's Daily Apple.

[fishermariawo]

Dear Mark: Iron Followup

Last week’s post on iron levels got a big response and garnered a ton of questions from you guys. Today, I’m going to clarify a few things and answer as many questions as I can. First, do iron and ferritin levels mean different things for men and women? If so, how do those differences manifest? What about premenopausal women vs postmenopausal women? Second, what do we make of the fact that ferritin is also increased in times of inflammation? Is there a way to distinguish between elevated ferritin caused by inflammation and elevated ferritin caused by high iron? Third, is desiccated liver a good option for liver haters? And finally, I share some exciting plague news.

Let’s go:

Emma wrote:

I’d love to see more info on iron levels as they relate to men and women differently. I recently had an iron infusion for low ferretin, not thinking much would change I actually experienced so many positive effects I didn’t even know were coming my way. I’m less cold, no more afternoon fatigue, less hair falling out, no more random palpitations, improved restless leg syndrome and the number one big change is it improved anxiety levels – in fact my anxiety is now gone. The last two are due to a connection between iron and dopamine. I learnt that children with mental health issues are often treated for low ferretin where possible, elevating levels to around 100 showing positive results (would love to see literature on this), for me my ferretin went from 20 to 130 and its changed my life, at 31 I haven’t felt this good in years. Yay iron!

That’s awesome to hear. Yes, it’s important to stress the very basic essentiality of iron. Without it, we truly cannot produce energy. And since energy is the currency for everything that happens in the body, an iron deficiency makes everything start to fall apart.

As for gender and iron, there’s a lot to discuss.

A good portion of women with hemochromatosis never actually express it phenotypically, meaning their lab tests don’t show evidence of dysregulated iron metabolism or storage. According to one study of hemochromatosis homozygotes (people who inherited the mutation from both of their parents), being a woman makes it 16x more likely that your hereditary hemochromatosis won’t actually present as iron overload.

Another study found that among mostly-age-matched men (42 years) and women (39 years) with hemochromatosis, 78% of the men had iron overload while just 36% of the women had it. Iron overload was defined as transferrin saturation over 52% combined with ferritin levels of 300 ng/mL for men and 200 ng/mL for women.

High iron levels are more of an issue for postmenopausal women than premenopausal women. The latter group regularly sheds blood through menstruation, and if anything, they’re at a higher risk of low iron. Plus, estrogen is a key regulator of iron metabolism. As menopause sets in and estrogen diminishes, that regulation suffers.

For instance:

In postmenopausal Korean women, high ferritin levels predict metabolic syndrome and subclinical atherosclerosis.

High ferritin predicts metabolic syndrome in postmenopausal but not premenopausal women.

In premenopausal Korean women, higher ferritin levels predict better bone mineral density; menopause nullifies this relationship.

Remember that ferritin is actually a measurable protein bound to iron, so testing a ferritin level is technically an indirect way to measure iron. Why is this important? Another characteristic of ferritin (the protein) is that it is an ACUTE PHASE REACTANT. This means that ferritin levels can fluctuate with illnesses and other inflammatory states in the body that drive up a ferritin value that is not related to an actual iron level fluctuation. Don’t get ferritin checked when you are sick with a cold or other illness.

This is a great point.

Ferritin is marker of long term iron storage, but it’s also an acute phase reactant that up regulates in response to inflammation or oxidative stress.

If you want to be really careful, you should get a HS-CRP test—that measures your overall inflammatory status. If CRP is elevated, ferritin can be elevated without saying anything about your iron status.

Come to think of it, if elevated ferritin can be a marker of inflammation and oxidative stress, the inflammation could be responsible for some of the negative health effects linked to high ferritin. Or, if having too much iron in the body can increase oxidative damage, it may be that high iron levels are increasing inflammation which in turn increases ferritin even further. Biology gets messy. Lots of feedback loops. However, the fact that many studies cited in the previous iron post that use blood donation to treat high ferritin have positive results indicates that for most people, ferritin can be, in most situations, an accurate estimation of your iron status.

To make sure it’s an iron problem, get a transferrin saturation test as well. That indicates the amount of iron you’re absorbing, with below 20% being low and over 45% being high. People with high ferritin and high transferrin saturation do have high iron levels. People whose ferritin is artificially enhanced by inflammation will have normal transferrin saturation levels.

I have one last question on this. You say “Don’t stop eating liver every week.” If you can’t stand the taste of liver, what do you think about taking liver capsules made from grass-fed New Zealand beef every day instead?

That’s a great option. Go for it.

People should generally aim for 4-8 ounces of fresh liver a week. Note the amount of desiccated liver in your capsules and multiply by 3 to get the fresh liver equivalent, then take enough each day (or all at once) to hit 4-8 ounces over the week. I hear good things about this one.

Mark, Thank you for your article on HH. I carry the gene but have been managing my iron levels through phlebotomies. I am full Keto, meat and all and have found my iron levels have not been effected by going Keto. Early detection is the key and ongoing monitoring. Bring on the plague!!!

You joke about that now, but there’s a startup that’s breeding heritage rat fleas that produce a mild strain of the plague that evades the attention of the immune system and proliferates throughout the body to keep iron levels in check without killing you. I’m an early investor, have a couple swarms installed in my condo, and (knock on wood) so far have avoided anything worse than a sore throat and maybe a mild open sore or two. There’s actually a big rift forming between the techs who want to keep the fleas heritage and those who want to go ahead with CRISPR and engineer them. One variant has had a deer tick gene inserted that adds an anesthetic compound to the flea’s saliva. That way you can have a personal swarm on you and never feel any bites or itches.

I’m not sure about CRISPR just yet, but I gotta say it’s pretty nice to be covered in fleas and not feel the bites. Time will tell.

Ok, I’m joking.

That’s it for today, folks. I hope I’ve answered some of your concerns, and if not, let me know down below. Thanks for reading!

Want to make fat loss easier? Try the Definitive Guide for Troubleshooting Weight Loss for free here.

References:

Lainé F, Jouannolle AM, Morcet J, et al. Phenotypic expression in detected C282Y homozygous women depends on body mass index. J Hepatol. 2005;43(6):1055-9.

Qian Y, Yin C, Chen Y, et al. Estrogen contributes to regulating iron metabolism through governing ferroportin signaling via an estrogen response element. Cell Signal. 2015;27(5):934-42.

Seo SK, Yun BH, Chon SJ, et al. Association of serum ferritin levels with metabolic syndrome and subclinical coronary atherosclerosis in postmenopausal Korean women. Clin Chim Acta. 2015;438:62-6.

Cho GJ, Shin JH, Yi KW, et al. Serum ferritin levels are associated with metabolic syndrome in postmenopausal women but not in premenopausal women. Menopause. 2011;18(10):1120-4.

Chon SJ, Choi YR, Roh YH, et al. Association between levels of serum ferritin and bone mineral density in Korean premenopausal and postmenopausal women: KNHANES 2008-2010. PLoS ONE. 2014;9(12):e114972.

The post Dear Mark: Iron Followup appeared first on Mark's Daily Apple.

[watsonrodriquezie]

Dear Mark: Iron Followup

Last week’s post on iron levels got a big response and garnered a ton of questions from you guys. Today, I’m going to clarify a few things and answer as many questions as I can. First, do iron and ferritin levels mean different things for men and women? If so, how do those differences manifest? What about premenopausal women vs postmenopausal women? Second, what do we make of the fact that ferritin is also increased in times of inflammation? Is there a way to distinguish between elevated ferritin caused by inflammation and elevated ferritin caused by high iron? Third, is desiccated liver a good option for liver haters? And finally, I share some exciting plague news.

Let’s go:

Emma wrote:

I’d love to see more info on iron levels as they relate to men and women differently. I recently had an iron infusion for low ferretin, not thinking much would change I actually experienced so many positive effects I didn’t even know were coming my way. I’m less cold, no more afternoon fatigue, less hair falling out, no more random palpitations, improved restless leg syndrome and the number one big change is it improved anxiety levels – in fact my anxiety is now gone. The last two are due to a connection between iron and dopamine. I learnt that children with mental health issues are often treated for low ferretin where possible, elevating levels to around 100 showing positive results (would love to see literature on this), for me my ferretin went from 20 to 130 and its changed my life, at 31 I haven’t felt this good in years. Yay iron!

That’s awesome to hear. Yes, it’s important to stress the very basic essentiality of iron. Without it, we truly cannot produce energy. And since energy is the currency for everything that happens in the body, an iron deficiency makes everything start to fall apart.

As for gender and iron, there’s a lot to discuss.

A good portion of women with hemochromatosis never actually express it phenotypically, meaning their lab tests don’t show evidence of dysregulated iron metabolism or storage. According to one study of hemochromatosis homozygotes (people who inherited the mutation from both of their parents), being a woman makes it 16x more likely that your hereditary hemochromatosis won’t actually present as iron overload.

Another study found that among mostly-age-matched men (42 years) and women (39 years) with hemochromatosis, 78% of the men had iron overload while just 36% of the women had it. Iron overload was defined as transferrin saturation over 52% combined with ferritin levels of 300 ng/mL for men and 200 ng/mL for women.

High iron levels are more of an issue for postmenopausal women than premenopausal women. The latter group regularly sheds blood through menstruation, and if anything, they’re at a higher risk of low iron. Plus, estrogen is a key regulator of iron metabolism. As menopause sets in and estrogen diminishes, that regulation suffers.

For instance:

In postmenopausal Korean women, high ferritin levels predict metabolic syndrome and subclinical atherosclerosis.

High ferritin predicts metabolic syndrome in postmenopausal but not premenopausal women.

In premenopausal Korean women, higher ferritin levels predict better bone mineral density; menopause nullifies this relationship.

Remember that ferritin is actually a measurable protein bound to iron, so testing a ferritin level is technically an indirect way to measure iron. Why is this important? Another characteristic of ferritin (the protein) is that it is an ACUTE PHASE REACTANT. This means that ferritin levels can fluctuate with illnesses and other inflammatory states in the body that drive up a ferritin value that is not related to an actual iron level fluctuation. Don’t get ferritin checked when you are sick with a cold or other illness.

This is a great point.

Ferritin is marker of long term iron storage, but it’s also an acute phase reactant that up regulates in response to inflammation or oxidative stress.

If you want to be really careful, you should get a HS-CRP test—that measures your overall inflammatory status. If CRP is elevated, ferritin can be elevated without saying anything about your iron status.

Come to think of it, if elevated ferritin can be a marker of inflammation and oxidative stress, the inflammation could be responsible for some of the negative health effects linked to high ferritin. Or, if having too much iron in the body can increase oxidative damage, it may be that high iron levels are increasing inflammation which in turn increases ferritin even further. Biology gets messy. Lots of feedback loops. However, the fact that many studies cited in the previous iron post that use blood donation to treat high ferritin have positive results indicates that for most people, ferritin can be, in most situations, an accurate estimation of your iron status.

To make sure it’s an iron problem, get a transferrin saturation test as well. That indicates the amount of iron you’re absorbing, with below 20% being low and over 45% being high. People with high ferritin and high transferrin saturation do have high iron levels. People whose ferritin is artificially enhanced by inflammation will have normal transferrin saturation levels.

I have one last question on this. You say “Don’t stop eating liver every week.” If you can’t stand the taste of liver, what do you think about taking liver capsules made from grass-fed New Zealand beef every day instead?

That’s a great option. Go for it.

People should generally aim for 4-8 ounces of fresh liver a week. Note the amount of desiccated liver in your capsules and multiply by 3 to get the fresh liver equivalent, then take enough each day (or all at once) to hit 4-8 ounces over the week. I hear good things about this one.

Mark, Thank you for your article on HH. I carry the gene but have been managing my iron levels through phlebotomies. I am full Keto, meat and all and have found my iron levels have not been effected by going Keto. Early detection is the key and ongoing monitoring. Bring on the plague!!!

You joke about that now, but there’s a startup that’s breeding heritage rat fleas that produce a mild strain of the plague that evades the attention of the immune system and proliferates throughout the body to keep iron levels in check without killing you. I’m an early investor, have a couple swarms installed in my condo, and (knock on wood) so far have avoided anything worse than a sore throat and maybe a mild open sore or two. There’s actually a big rift forming between the techs who want to keep the fleas heritage and those who want to go ahead with CRISPR and engineer them. One variant has had a deer tick gene inserted that adds an anesthetic compound to the flea’s saliva. That way you can have a personal swarm on you and never feel any bites or itches.

I’m not sure about CRISPR just yet, but I gotta say it’s pretty nice to be covered in fleas and not feel the bites. Time will tell.

Ok, I’m joking.

That’s it for today, folks. I hope I’ve answered some of your concerns, and if not, let me know down below. Thanks for reading!

Want to make fat loss easier? Try the Definitive Guide for Troubleshooting Weight Loss for free here.

References:

Lainé F, Jouannolle AM, Morcet J, et al. Phenotypic expression in detected C282Y homozygous women depends on body mass index. J Hepatol. 2005;43(6):1055-9.

Qian Y, Yin C, Chen Y, et al. Estrogen contributes to regulating iron metabolism through governing ferroportin signaling via an estrogen response element. Cell Signal. 2015;27(5):934-42.

Seo SK, Yun BH, Chon SJ, et al. Association of serum ferritin levels with metabolic syndrome and subclinical coronary atherosclerosis in postmenopausal Korean women. Clin Chim Acta. 2015;438:62-6.

Cho GJ, Shin JH, Yi KW, et al. Serum ferritin levels are associated with metabolic syndrome in postmenopausal women but not in premenopausal women. Menopause. 2011;18(10):1120-4.

Chon SJ, Choi YR, Roh YH, et al. Association between levels of serum ferritin and bone mineral density in Korean premenopausal and postmenopausal women: KNHANES 2008-2010. PLoS ONE. 2014;9(12):e114972.

The post Dear Mark: Iron Followup appeared first on Mark's Daily Apple.

[cynthiamwashington]

Dear Mark: Iron Followup

Last week’s post on iron levels got a big response and garnered a ton of questions from you guys. Today, I’m going to clarify a few things and answer as many questions as I can. First, do iron and ferritin levels mean different things for men and women? If so, how do those differences manifest? What about premenopausal women vs postmenopausal women? Second, what do we make of the fact that ferritin is also increased in times of inflammation? Is there a way to distinguish between elevated ferritin caused by inflammation and elevated ferritin caused by high iron? Third, is desiccated liver a good option for liver haters? And finally, I share some exciting plague news.

Let’s go:

Emma wrote:

I’d love to see more info on iron levels as they relate to men and women differently. I recently had an iron infusion for low ferretin, not thinking much would change I actually experienced so many positive effects I didn’t even know were coming my way. I’m less cold, no more afternoon fatigue, less hair falling out, no more random palpitations, improved restless leg syndrome and the number one big change is it improved anxiety levels – in fact my anxiety is now gone. The last two are due to a connection between iron and dopamine. I learnt that children with mental health issues are often treated for low ferretin where possible, elevating levels to around 100 showing positive results (would love to see literature on this), for me my ferretin went from 20 to 130 and its changed my life, at 31 I haven’t felt this good in years. Yay iron!

That’s awesome to hear. Yes, it’s important to stress the very basic essentiality of iron. Without it, we truly cannot produce energy. And since energy is the currency for everything that happens in the body, an iron deficiency makes everything start to fall apart.

As for gender and iron, there’s a lot to discuss.

A good portion of women with hemochromatosis never actually express it phenotypically, meaning their lab tests don’t show evidence of dysregulated iron metabolism or storage. According to one study of hemochromatosis homozygotes (people who inherited the mutation from both of their parents), being a woman makes it 16x more likely that your hereditary hemochromatosis won’t actually present as iron overload.

Another study found that among mostly-age-matched men (42 years) and women (39 years) with hemochromatosis, 78% of the men had iron overload while just 36% of the women had it. Iron overload was defined as transferrin saturation over 52% combined with ferritin levels of 300 ng/mL for men and 200 ng/mL for women.

High iron levels are more of an issue for postmenopausal women than premenopausal women. The latter group regularly sheds blood through menstruation, and if anything, they’re at a higher risk of low iron. Plus, estrogen is a key regulator of iron metabolism. As menopause sets in and estrogen diminishes, that regulation suffers.

For instance:

In postmenopausal Korean women, high ferritin levels predict metabolic syndrome and subclinical atherosclerosis.

High ferritin predicts metabolic syndrome in postmenopausal but not premenopausal women.

In premenopausal Korean women, higher ferritin levels predict better bone mineral density; menopause nullifies this relationship.

Remember that ferritin is actually a measurable protein bound to iron, so testing a ferritin level is technically an indirect way to measure iron. Why is this important? Another characteristic of ferritin (the protein) is that it is an ACUTE PHASE REACTANT. This means that ferritin levels can fluctuate with illnesses and other inflammatory states in the body that drive up a ferritin value that is not related to an actual iron level fluctuation. Don’t get ferritin checked when you are sick with a cold or other illness.

This is a great point.

Ferritin is marker of long term iron storage, but it’s also an acute phase reactant that up regulates in response to inflammation or oxidative stress.

If you want to be really careful, you should get a HS-CRP test—that measures your overall inflammatory status. If CRP is elevated, ferritin can be elevated without saying anything about your iron status.

Come to think of it, if elevated ferritin can be a marker of inflammation and oxidative stress, the inflammation could be responsible for some of the negative health effects linked to high ferritin. Or, if having too much iron in the body can increase oxidative damage, it may be that high iron levels are increasing inflammation which in turn increases ferritin even further. Biology gets messy. Lots of feedback loops. However, the fact that many studies cited in the previous iron post that use blood donation to treat high ferritin have positive results indicates that for most people, ferritin can be, in most situations, an accurate estimation of your iron status.

To make sure it’s an iron problem, get a transferrin saturation test as well. That indicates the amount of iron you’re absorbing, with below 20% being low and over 45% being high. People with high ferritin and high transferrin saturation do have high iron levels. People whose ferritin is artificially enhanced by inflammation will have normal transferrin saturation levels.

I have one last question on this. You say “Don’t stop eating liver every week.” If you can’t stand the taste of liver, what do you think about taking liver capsules made from grass-fed New Zealand beef every day instead?

That’s a great option. Go for it.

People should generally aim for 4-8 ounces of fresh liver a week. Note the amount of desiccated liver in your capsules and multiply by 3 to get the fresh liver equivalent, then take enough each day (or all at once) to hit 4-8 ounces over the week. I hear good things about this one.

Mark, Thank you for your article on HH. I carry the gene but have been managing my iron levels through phlebotomies. I am full Keto, meat and all and have found my iron levels have not been effected by going Keto. Early detection is the key and ongoing monitoring. Bring on the plague!!!

You joke about that now, but there’s a startup that’s breeding heritage rat fleas that produce a mild strain of the plague that evades the attention of the immune system and proliferates throughout the body to keep iron levels in check without killing you. I’m an early investor, have a couple swarms installed in my condo, and (knock on wood) so far have avoided anything worse than a sore throat and maybe a mild open sore or two. There’s actually a big rift forming between the techs who want to keep the fleas heritage and those who want to go ahead with CRISPR and engineer them. One variant has had a deer tick gene inserted that adds an anesthetic compound to the flea’s saliva. That way you can have a personal swarm on you and never feel any bites or itches.

I’m not sure about CRISPR just yet, but I gotta say it’s pretty nice to be covered in fleas and not feel the bites. Time will tell.

Ok, I’m joking.

That’s it for today, folks. I hope I’ve answered some of your concerns, and if not, let me know down below. Thanks for reading!

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Want to make fat loss easier? Try the Definitive Guide for Troubleshooting Weight Loss for free here.

window.onload=function(){ga('send', { hitType: 'event', eventCategory: 'Ad Impression', eventAction: '65477' });}

References:

Lainé F, Jouannolle AM, Morcet J, et al. Phenotypic expression in detected C282Y homozygous women depends on body mass index. J Hepatol. 2005;43(6):1055-9.

Qian Y, Yin C, Chen Y, et al. Estrogen contributes to regulating iron metabolism through governing ferroportin signaling via an estrogen response element. Cell Signal. 2015;27(5):934-42.

Seo SK, Yun BH, Chon SJ, et al. Association of serum ferritin levels with metabolic syndrome and subclinical coronary atherosclerosis in postmenopausal Korean women. Clin Chim Acta. 2015;438:62-6.

Cho GJ, Shin JH, Yi KW, et al. Serum ferritin levels are associated with metabolic syndrome in postmenopausal women but not in premenopausal women. Menopause. 2011;18(10):1120-4.

Chon SJ, Choi YR, Roh YH, et al. Association between levels of serum ferritin and bone mineral density in Korean premenopausal and postmenopausal women: KNHANES 2008-2010. PLoS ONE. 2014;9(12):e114972.

The post Dear Mark: Iron Followup appeared first on Mark's Daily Apple.

Article source here:Marks’s Daily Apple