#celigo implementation

[integscloud]

How Is Ecommerce Integration Revolutionary? 5 Big Reasons To Adapt Celigo!

In a world where most business markets are over-saturated and new enterprises are ever-emerging with progressive developments, fancier technology, and constant improvements, the customer’s viewpoint of an e-commerce entity has transformed. The undeniable truth is that if your business is not automated via eCommerce integration, it will be left behind in the new-age business world.

The expectations of a new-age customer now include perfect customer service, faster shipping, 100% accuracy, and a flawless experience from any eCommerce they interact with. These expectations have been fostered by rapid technological developments- both in the eCommerce field and at an individual company level. Continuous improvement in software and technology is what has accelerated eCommerce businesses to perform significantly better.

But how exactly does eCommerce integration through platforms like Celigo contribute to holistic development?

Imagine you own a sports clothing brand. Your revenue points include your own website, third-party platforms like Amazon, eBay, Flipkart, Myntra, etc., and several physical retail shops across your state. Now imagine connecting the sales data, inventory information, and revenue report from these 3 to get a clear and precise data pointer from any one front in a few minutes!

Ecommerce integrations along with Celigo act as the glue between varied pointers and give you this information.

Apart from this added ease, with eCommerce integration and automation, the scalability and growth of your business become more manageable, making it better for your internal operations. You get better control from better insights. These are the 3 major growth curves eCommerce integration solutions bring to your processes:

They’re faster

They’re more cost-effective

And they’re error-free!

In fact, internal strategies and innovations are only better via smoother, more accurate, and more effective operations!

But these are just some of the generic benefits that barely scratch the surface. E-commerce integrations and automation dive much deeper. Celigo Integrations don’t just automate single functions, they directly tackle big processes completely- right from retail, to inventory management & tracking, to logistics & supply chains, and even your finances and evaluations. Here are 5 big benefits of Celigo that can completely revolutionize the way your business and eCommerce operate.

5 Benefits Of Ecommerce Integrations Via Celigo For Your Business!

1. Transparent Online Shopping & Faster Order Processing

Customer experience is also further enhanced by their online shopping and what happens right after they place the order. With Celigo, you can seamlessly connect all your applications. For example, you can connect your Shopify with your payment, ERP, and logistics. Through this, your customers get real-time updates if a product is out of stock while shopping online.

Similarly, with order processing, ecommerce integration can accelerate the speed of delivery! Manual processes tend to eat up loads of time for simple processing. But through automation, an order can be processed right after it’s placed. You can also auto-send emails of confirmation along with the delivery and tracking right away for a worry & hassle-free process.

2. Fulfillment & Shipping

Customers look forward to one thing the most- receiving what they have ordered. The process that takes place after the order has been placed usually involves countless manual processes- that tend to lengthen the overall time. Through ecommerce integration and automation, you can gain total control of your inventory through tracking and managing.

3. Helps Beat Competition

With Celigo’s eCommerce integration solutions and tools, you can integrate your operations in a way that is risk-free and shows faster results. Usually, a newly launched business does not take off right away. Some of the highly useful connectors coming from Celigo help customize integration between cloud apps and are also prebuilt. You get to utilize custom integration via a platform that is extremely easy to use!

With ecommerce integration, you also get a clearer view of who, what, and where to target. All these tools give you a chance to perform infinitely better. The real way to beat the competition is by offering something better than them. You can do this by providing a better customer experience. Through ecommerce integration solutions and tools, you can track customers and their buying patterns for a customized experience on your website.

4. Great Internal Coordination

The frictionless coordination among employees is what really makes or breaks how your business operates. Obstacles in communication can result in failed plans made beforehand or results that are not of the best quality. With ecommerce integration, the tools from Celigo help build a strong communication channel.

These also contribute to eliminating more than half of the manual processes that come with traditional ecommerce methods. Employees are given the liberty to focus more vividly on strategies and communication, leading to excellent internal coordination.

5. Honest & Effective Communication

Trust-building and reliability are 2 massive attributes that help win over customers in the long run. The best way to create these is through honest, yet convincing communication. Effective communication often happens face-to-face. But with Celigo, these tools help facilitate communication- from both ends- to be more honest and elaborate.

Conclusion

Overall, ecommerce integration platforms like Celigo simplify tedious business processes to make them work in a manner that benefits everyone. For your business to take off with the help of ecommerce, NetSuite, and Celigo expertise, you need a consultant who is fantastic on all three fronts. This is where Integs Cloud Technologies comes into the picture!

An experienced company makes sure your business structure becomes completely automated in a hassle-free manner and smooth way. Call us today for a consultation!

[vnmt]

Choosing the Right iPaaS for NetSuite: Is Celigo the Right Choice?

The management of numerous business applications, along with straightforward data connection between systems creates challenges for organizations during expansion. NetSuite operates as the primary cloud-based ERP solution for businesses since its integration with external systems represents a complex process. The integration solution provided by Integration Platform as a Service (iPaaS) unifies NetSuite Integration Services with various applications through an efficient operational setup.

What is iPaaS?

iPaaS functions as a cloud platform that enables businesses to unite diverse software applications and automate workflow processing while enhancing data exchange capabilities. The low-code or no-code capabilities across iPaaS enable integration approaches that avoid custom development and unnecessary maintenance costs while promoting access for users.

5 Powerful Reasons to Use iPaaS for NetSuite Integration Services

Seamless Connectivity: An iPaaS platform makes it easy to synchronize NetSuite data with CRM solutions alongside eCommerce systems and accounting software as well as other enterprise applications. iPass provides preconfigured connectors alongside APIs that obviate the necessity for writing lengthy codes through custom development. A streamlined system operates through different software solutions to enable businesses to create one digital unified environment.

Real-time Data Synchronization: The technology provides businesses with instant automatic data synchronization capabilities that span across all associated applications. iPass executes real-time information synchronization that minimizes contradictions and duplicates records eliminating manual mistakes for details involving customers and financial transactions along with inventory updates. An accurate data flow enables better business decisions through recent insights while enabling enhanced operational efficiency.

Scalability & Flexibility: Organizations that scale their operations require an integration platform as a service for seamless application implementation which requires minimal infrastructure transformations. The ability of NetSuite Integration to adapt to business requirements depends on iPaaS which supports market expansion together with additional software implementation and increased transaction capacity.

Automation & Process Optimization: The platform automates entire key processes from order processing to invoicing to customer data management to financial reconciliations, thus, removing operational delays along with human error probabilities. The automated system leads to productivity growth together with cost minimization and business operational efficiency that enables team members to address essential high-value activities.

Enhanced Security & Regulatory Compliance: Integration Platform as a Service (iPaaS) protects business-critical data through its included security functionalities as well as its encryption features and its capacity to meet regulatory requirements. Business trust develops through organization compliance with GDPR, HIPAA, and SOX standards which protect sensitive customer and financial information.

What are the major challenges with iPaaS NetSuite Integration?

Implementing NetSuite Integration Services often brings in numerous hurdles for businesses since managing it is a complex process, which includes:

Limited Customization: The pre-built connectors in NetSuite might not satisfy unique business process requirements. Companies having distinctive operational methods struggle to discover adaptable integration solutions that satisfy their business requirements.

Complex Data Mapping: NetSuite demands strict data formatting through which companies experience challenges when connecting their systems to external programs. Imperfect data structure alignment produces errors that force employees to invest significant time in mapping and transforming the information.

Scalability Issues: The growth of businesses reveals that manual integration procedures become unproductive for daily operations. Systems that perform transaction handling together with multiple data entry points will experience slowdowns when they lack automation thus they develop processing bottlenecks.

Error Handling & Data Sync Delays: The synchronization of NetSuite with other systems depends on having strong error management systems. Business operations face interruptions and flawed decision-making occurs when data fails to match properly and update delays occur because of inadequate monitoring.

Key Use Cases of iPaaS in NetSuite Integration Services

Businesses using NetSuite integration services from an iPaaS platform build a unified automated digital system that helps them expand while optimizing their operations and supplying complete data circulation throughout the organization.

eCommerce Integration: NetSuite connects smoothly with Shopify, Magento, and WooCommerce. This ensures inventory numbers match, order tracking updates sync and customer information stays accurate for an optimal shopping experience.

CRM Integration: NetSuite links with Salesforce, HubSpot, and Zoho CRM. Sales and customer support teams can access customer communication history, sales documentation, and lead details on a single platform.

Finance & Accounting Integration: NetSuite integrates with QuickBooks, Xero, and SAP. This allows real-time transaction updates, complete financial reporting, and streamlined reconciliation for higher system accuracy.

HR & Payroll Integration: NetSuite connects with Workday, BambooHR, and ADP. This ensures consistency between HR and payroll processes, improving overall efficiency.

Is Celigo the Best iPaaS Solution for NetSuite Integration?

The iPaaS service provider Celigo was built to enhance NetSuite integration features specifically for its users. The solution offers ready-made connectors, automation capabilities, and workflow customization. It enables seamless NetSuite Integration with various systems without requiring advanced coding knowledge.

Extensive Pre-Built Connectors: The platform connects easily through pre-existing connectors for popular business applications starting from Salesforce and including Shopify and Amazon together with QuickBooks and multiple others. A feature of pre-configured connectors operates as a time-saving and dependable mechanism to enable data exchange between systems.

User-Friendly Interface: The user-friendly interface of Celigo includes a drag-and-drop mechanism that enables easy workflow automation for all users. The user-friendly design of Celigo allows anyone to create and alter integrations through its visual interface which makes them independent from IT support.

Scalability and Customization: Celigo distinguishes itself as an outstanding integration solution through its implementation of features that adjust capabilities according to business requirements from small companies to large corporations. Businesses achieve adaptability through time by using the system to modify workflows when adding new applications through its flexible structure.

Advanced Error Handling and Real-Time Monitoring: Businesses using NetSuite depend on constant data operation since they need uninterrupted data flow. Celigo tracks operations in real-time and automatically detects and fixes integration problems thus preventing any disruption to business operations.

Wrapping Up!

Celigo offers businesses the best combination of power and user-friendly capabilities to smoothly integrate NetSuite with various enterprise applications through its iPaaS solution. Organizations seeking operation streamlining solutions should consider this tool because it offers user-friendly frameworks and built-in connectors together with automation abilities that function effectively without complex technical know-how.

However, deciding on the right NetSuite integration service provider requires a thorough examination of organizational needs by companies. You can connect with VNMT Solutions, one of the best NetSuite integration service-providing companies, to streamline your business and undertake seamless operations. Therefore, you need to compare various integration platforms with Celigo’s feature selection before determining the best platform fit for their requirements.

Source: https://vnmt-solutions.medium.com/choosing-the-right-ipaas-for-netsuite-is-celigo-the-right-choice-d301a03ca85a

[erppeers]

ERP Peers is a leading NetSuite service provider, helping businesses achieve exceptional growth. We streamline and automate operations through our expertise in NetSuite and Celigo.

Our Peers provides a suite of tailored NetSuite ERP services, including consulting, implementation, customization, integration, and ongoing support to fit the unique needs of businesses like yours. 

By using powerful iPaaS platforms like Celigo, we integrate your ERP system effortlessly with existing applications. This guarantees smooth data flow and eliminates information silos, promoting a unified and efficient business ecosystem, whether it is a startup or an established enterprise.

With your Peers beside you, you can rest assured that your systems will grow with you, never becoming a barrier to success.

[oditeksolutionsyaass]

Kronos, a leading workforce management solution, offers cloud-based tools for time and attendance tracking, schedule management, and payroll automation. OdiTek Solutions specializes in implementing and optimizing Kronos modules, providing services for Kronos Workforce Ready, Dimensions, Central, Analytics, TeleStaff, and more.

Services offered by OdiTek include customized implementation, seamless integration with existing systems, compliance and reporting configuration, and continuous support and optimization. The team's expertise extends to cloud integration with tools like Boomi, Celigo, and Workato.

OdiTek ensures precise configuration of Kronos solutions, compliance with labor laws, and ongoing support for long-term efficiency. As a strategic consulting partner, they aim to enhance workforce management and offer expertise in Kronos Workforce Ready and Kronos Workforce Dimensions.

Kronos Integration, Kronos UKG, Kronos Work Force Ready, Kronos Scheduling, Kronos Workday

[closeloop]

NetSuite integration is essential for modern businesses to ensure seamless data flow across all organizational levels. This enables enhanced collaboration, streamlined operations, and improved customer experiences. Integrations with platforms like Boomi, Salesforce, Shopify, HubSpot, FreshDesk, Celigo, Magento, WooCommerce, and more provide specific benefits tailored to various business needs.  Consulting with NetSuite implementation experts is crucial for tailored integration solutions.

[1234455676fawcd]

Streamlining Business Operations: Unleashing the Power of Celigo Net Suite Integration

Streamlining Business Operations: Unleashing the Power of Celigo Net Suite Integration

In today's fast-paced business landscape, efficiency and seamless operations are essential for success. As organizations grow and expand, they often find themselves dealing with an increasingly complex web of processes, systems, and data. This is where Celigo NetSuite Integration steps in, offering a robust solution to streamline operations and propel businesses towards greater heights.

The Challenge of Siloed Systems

One of the most significant challenges faced by businesses is the presence of disparate systems that operate in isolation. Various departments often use specialized software and tools to manage their operations, resulting in data silos and disjointed processes. This lack of integration can lead to inefficiencies, errors, and delays in decision-making.

Enter Celigo NetSuite Integration – a comprehensive platform designed to connect different software applications and enable seamless data flow across the organization. By bridging the gap between various systems, businesses can eliminate redundancy, enhance collaboration, and gain a holistic view of their operations.

The Power of Celigo NetSuite Integration

Celigo NetSuite Integration offers a wide range of features and benefits that can revolutionize the way businesses operate:

1. Real-time Data Synchronization

With Celigo NetSuite Integration, data synchronization becomes a breeze. Whether it's customer information, sales orders, inventory levels, or financial data, the integration platform ensures that all your systems are up-to-date in real-time. This accuracy and timeliness empower teams to make informed decisions and respond swiftly to market changes.

2. Process Automation

Manual data entry and repetitive tasks can drain valuable time and resources. Celigo NetSuite Integration allows businesses to automate workflows across different applications. From order-to-cash processes to lead-to-opportunity conversions, automation reduces errors, accelerates processes, and frees up employees to focus on high-value tasks.

3. Enhanced Customer Experience

A unified view of customer data enables personalized and responsive interactions. With Celigo NetSuite Integration, customer support and sales teams can access the latest information, enabling them to provide exceptional service and build stronger relationships. From order history to preferences, every touchpoint becomes an opportunity to delight customers.

4. Scalability and Growth

As businesses expand, their software ecosystem tends to grow as well. Celigo NetSuite Integration is built to scale alongside your organization, accommodating new applications and systems seamlessly. This scalability ensures that your operations remain efficient and adaptable, even as you enter new markets or launch innovative products.

Implementing Celigo NetSuite Integration

Integrating systems using Celigo NetSuite Integration is a strategic move that requires careful planning and execution:

1. Assessment and Planning

Begin by assessing your current systems, processes, and integration needs. Identify the key workflows that can benefit from integration and outline your objectives. Collaborate with cross-functional teams to ensure alignment and a clear understanding of the integration's impact.

2. Customization

Celigo NetSuite Integration offers a range of pre-built connectors and templates to simplify the integration process. However, each business is unique, and customization might be necessary to address specific requirements. Work with experts or leverage the platform's customization options to tailor the integration to your organization's needs.

3. Data Mapping and Transformation

Mapping data between different systems is a critical step. Define how data will flow between applications and ensure that data formats and structures are compatible. Transformation rules may be needed to standardize data and maintain its integrity during the transfer.

4. Testing and Validation

Thorough testing is essential to identify and address any issues before the integration goes live. Create test scenarios to simulate real-world situations and validate that data is accurately synchronized. Testing helps mitigate risks and ensures a smooth transition for your operations.

5. Training and Adoption

Introducing a new integrated system involves change for your employees. Provide comprehensive training to ensure that teams understand how to use the integrated platform effectively. Encourage adoption by highlighting the benefits and demonstrating how the integration simplifies their tasks.

Embrace the Future of Seamless Operations

In a digital era where connectivity and data-driven insights reign supreme, Celigo NetSuite Integration emerges as a catalyst for business transformation. By breaking down silos, automating processes, and delivering a unified view of operations, organizations can achieve unparalleled efficiency and agility.

As you embark on your integration journey, partner with experienced consultants or tap into Celigo's support resources to maximize the benefits. With Celigo NetSuite Integration as your operational backbone, your business can confidently embrace the future and navigate the ever-evolving business landscape. Streamline your operations, unleash the power of integration, and position your business for sustainable growth and success.

[technosip]

How to Improve Automation with ERP System Integration?

What is ERP Automation?

ERP automation is the process of automating and simplifying business processes while getting rid of/reducing manual interventions. It helps businesses enhance the features and functions of the system, leveraging the potential power of AI technology.

Integrating automation in your ERP system can support various functions, such as finance, accounting, manufacturing, HR, sales, marketing, project management, and many more if you are a start-up, SME, or a large-scale organization.

With the help of automation & ERP integration, you can bring significant operational excellence, improve productivity, maximize profitability and promote growth in your business.  

Apart from this, there are so many benefits of ERP automation integration. Let’s have a look! 

Benefits of Integrating Automation in Your ERP System

Integrating automation in your ERP systems provides many benefits, from a cloud-deployed ERP system to on-premise one. 

Here they are! 

Eliminate the practice of using papers 

Centralized data in one system

Ensure document security 

Faster access to information for employees

Access to real-time data 

Make informed decisions based on accurate info

Better visibility into business relationships

Reduce manual and tedious work

Impose better control on operating costs

Attain more flexibility in process management

Improve customer service

Saves time and increases productivity

Popular Automation Integrations that are Perfect for the ERP System 

Below are a few automation integrations that are popular and preferred amongst clients for their ERP systems. They leverage the true power of AI and improve automation with their existing ERP system. 

Let’s check how it can complement your ERP system too. 

SAP

Integrating SAP into your ERP system can automate your manual work related to data entry, information routing, and many more. It also helps improve business productivity and cut costs spent on document storage or labor.

Salesforce

Salesforce is one of the best CRM systems you can integrate/automate your ERP system. It can help organizations manage relationships with customers and employees very well. With Salesforce automation integration, employees who want to retrieve a document or search the files can have instant access.

Microsoft Dynamics

You can integrate your ERP system with Microsoft dynamics and provide employees better access to tools, information, and functionality. It gives peace of mind to employees by not doing manual indexing or data entry.

Apart from this, there are so many automation integrations possible that can complement your ERP systems, such as Oracle, JD Edwards, Workday, Deltek cost point, and many more.

Conclusion

If you want to know how to bring automation into your ERP system or need a power-packed ERP system from scratch, we at Technosip can help! Our developers can help you build one or choose the best ERP system integrations suitable for your business needs. All you need to do is contact us; our experts are happy to help! For more information, you can email us at info@technosip.com or give us a call on +1 201 633 4050

[emaanderson]

Platform as a Service (PaaS) Market to Grow with a Significant CAGR during 2023-2035

Research Nester released a report titled “Platform as a Service (PaaS) Market: Global Demand Analysis & Opportunity Outlook 2035” which delivers detailed overview of the global platform as a service (PaaS) market in terms of market segmentation by type, vertical, and by region.

Further, for the in-depth analysis, the report encompasses the industry growth indicators, restraints, supply and demand risk, along with detailed discussion on current and future market trends that are associated with the growth of the market.

The global platform as a service (PaaS) market is projected to grow with a significant CAGR during the forecast period, i.e., 2023-2035, owing to the increasing need to decrease time to market (TTM) cost and reduce the cost of application development. Furthermore, PaaS can deploy the complete infrastructure over the internet that is required to develop, test, run, and set up programs. As a result of this, organizations are able to re-direct a chief percentage of their budgets in developing programs and specialize in software information, which in turn is expected to drive market growth in the coming years.

The market is segmented by type into application PaaS, integration PaaS, database PaaS, and others. Among these segments, the application PaaS (APaaS) segment is anticipated to garner the largest market share over the forecast period owing to the increasing implementation of APaaS applications among various government organizations, and in IT and telecommunication industries.

On the basis of region, the market is segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa, out of which, the market in Asia Pacific region is anticipated to grow at the highest CAGR over the forecast period ascribing to the growing investments by companies in ICT sector. Furthermore, the market in North America is evaluated to hold the largest share, which can be attributed to the rising budget allocation for cloud services among enterprises and well-established sectors including, telecommunication, BFSI, IT, government, and public sector.

Request Report Sample@

Increasing Need for Reduction of Application Cost to Drive Market Growth

When an application is deployed on-premise, it requires additional integration of database, hardware, middleware, operating system (OS), web services, and other software. On the other hand, PaaS has this entire infrastructure required to develop, run, deploy and test applications in-built over cloud, which helps in lowering the cost of implementing an application. This factor is anticipated to drive growth for the global platform as a service (PaaS) market in the upcoming years.

However, security issues regarding adoption of public cloud is estimated to hinder market growth over the forecast period.

This report also provides the existing competitive scenario of some of the key players of the global platform as a service (PaaS) market which includes company profiling of Boomi, Inc., Informatica LLC, Mulesoft LLC, Snaplogic Inc., Celigo, Inc., IBM Corporation, Oracle Corporation, Jitterbit, Inc., TIBCO Software Inc., Flowgear, SAP Group, and others. The profiling enfolds key information of the companies which encompasses business overview, products and services, key financials and recent news and developments.

On the whole, the report depicts detailed overview of the global platform as a service (PaaS) market that will help industry consultants, equipment manufacturers, existing players searching for expansion opportunities, new players searching possibilities and other stakeholders to align their market centric strategies according to the ongoing and expected trends in the future.

Request Report Sample@

[globaltalentexchange]

THE GTX EXPERIENCE: A TESTIMONIAL - NILESH KUMAR

Mr. Nilesh Kumar recently landed a job as a Senior Product Manager at Celigo, a Global Talent Exchange client.

Our team was interested in getting to know him better, understanding his career path, and getting feedback on his journey working with GTX.

Read on for excerpts from our conversation with the professional.

Could you give us a brief about yourself?

I’ve been in the IT industry for a total of 11 years now. My professional journey began with Oracle India where I worked in the implementation domain for 7 years. Post that, I went on to do my MBA from XLRI, a reputed University in Jamshedpur. I was hired by Infosys as a product manager and was with them for 3 years. Following that, I joined KPMG as an Assistant Manager. Now, I’ve just found a wonderful opportunity with Celigo as a Senior Product Manager.

What motivated you to look out for a job change? What was the main driving factor behind the decision?

I started my professional journey with consulting, and it was only after I completed my MBA that I was introduced to product management. That’s when I feel I found my true passion. I loved being a product manager. Though it was easy for me to land a job in consultancy, that’s not a role I felt “driven” in.

Thus, the major reason to look out for a job change was to make my way back into product management, as it is very important for me to have a sense of purpose in my work and feel the satisfaction that comes with it. Celigo gave me the perfect opportunity.

What progress do you seek professionally in this role? What do you hope to gain from it?

I feel that Product management is the heart of a business, and I’m pumped to be able to contribute to it. Moreover, I believe that digital transformation has been on the rise and Celigo is one such company that makes it possible. I want to be an enabler and a key part of it.

How long have you been on the lookout for a job change? How long did it take you to land a role with Celigo?

I was searching for about a month before I landed the perfect opportunity with Celigo. I gave two interviews, which I cracked, but preferred to go with Celigo. I had no dearth of opportunities from big names in the industry, but I was picky and didn’t settle till I found one that aligned with my belief and passion.

Global Talent Exchange brought me this opportunity and helped me a lot throughout.

Why did you decide to go with Celigo? What stood out?

The Glassdoor rating of the company was wildly impressive, and it was higher than any I had ever come across. It matched my expectations and gave me the space to be an enabler, as I mentioned.

The interview rounds gave me insight into the company culture, the leadership, and the open interactions. Moreover, the other employees in the company review it highly.

How did your journey with GTX begin?

I was contacted by someone from the GTX team who informed me about the available opportunity at Celigo.

How was your experience with the GTX team, from start to finish?

It was extremely smooth and there were several follow-ups from the team. The point of contact made sure that I was comfortable throughout and was exceptionally patient. She informed me of the requirements and made sure I have the Job description. Moreover, the process was made very transparent. She let me know what I should expect at each stage of the interview process, and what I should prepare, and gave me the time frame in which I should expect a response.

I would say it was an excellent job done by the team with smooth communication and an efficient transition process. The ease of the process enabled me to give my very best. It was an awesome experience with GTX.

What differences would you say were apparent between other recruiting platforms and GTX?

From my personal experience, I would say that during the interview process, there are lapses from both ends often- the employer and the employee.

GTX made sure there were no lapses during the entire process. The team was attentive and there was no slippage.

You’ve been in this industry for a while now, and you hadn’t heard of Celigo- yet found a wonderful opportunity with them. Do you think with the developments taking place in India- especially in Tech and IT, such impressive opportunities have sprouted throughout the nation at a very rapid pace?

I completely agree. India has become a magnet for talent. With the new companies that have come up of late, opportunities are growing vastly and the requirement for talent is booming.  

Without a doubt, it requires one to “take a plunge” to work for a relatively new company, but from my own experience, I can confidently say that it is necessary to take this plunge. It can be extremely rewarding. The salary structure has changed, and the work culture has improved- It’s a wonderful time for India.

Would you recommend GTX to your friends/colleagues?

Most definitely. GTX has given me one of the best opportunities of my life and is partnered with impressive companies like Celigo.

I would undoubtedly propose your name to my family/friends/colleagues who might be on the lookout for a good opportunity.

Seeking a job change or moving back to India, but don’t know where to begin?

GTX can help.

Log on to www.globaltalex.com or write to us at techrec@globaltalex.com for more information.

[truthshield]

Celigo Hires First CIO to Lead Innovation in Post-Digital Era

Focus will be on driving enterprise-wide automation using Celigo’s own platform    SAN MATEO, Calif., June 21, 2022 /PRNewswire/ — Celigo, the leading enterprise-wide Integration Platform as a Service (iPaaS), today announced the hiring of Asad Siddiqui as the company’s first Chief Information Officer (CIO) to lead innovation in the Post-Digital era. With the growing role of automation in digital transformation and shift in customer expectations of how that automation happens, now was the right time to put Siddiqui at the helm. He will help the company adopt an approach that enables agility and innovation across business teams without risking business resilience, scale and data security.  “It’s clear there has been a seismic shift in how businesses serve their customers and how their employees engage with technology, with their work, and with each other,” said Jan Arendtsz, Founder and CEO at Celigo. “The agility and innovative spirit born out of the pandemic is now a permanent part of the organizational culture. Meeting these new expectations demands that technology leaders reimagine their roles to empower this cultural change. Asad is the ideal person to lead this transformation at Celigo.” Siddiqui has worked with some of the world’s most forward-thinking tech companies, including Asana and LinkedIn, and brings years of experience building teams, technology, and strategies to compete in ever-changing digital landscapes. At Celigo, he will build and lead innovation squads that will develop and implement Celigo products to drive optimal automation within Celigo and for its customers and partners. “Digital transformation is a core element of being viable and competing in the industry. It continues to be a focus for CIOs and other executives, even as we move into a Post-Digital age,” said Asad Siddiqui, Chief Information Officer at Celigo. “Automation is at the heart of that transformation and I am looking forward to driving innovation through our own solutions and teams at Celigo.” To learn more about Celigo’s growing leadership team, please visit the Celigo website. About Celigo Celigo is the leading enterprise-wide Integration Platform as a Service (iPaaS). Named a G2 Best Software for 2021, Celigo enables breakaway growth, controlled cost management, and superior customer experiences by ensuring that every process — at any level of the organization — can be automated in the most optimal way. For more information, visit www.celigo.com. Follow us on LinkedIn, Twitter, and Facebook.  For more information, press only:BLASTmedia for Celigo 317.806.1900 [email protected] SOURCE Celigo, Inc https://ift.tt/FuRpQ2t https://ift.tt/iU7oTCd

[integscloud]

Picture this. You are a part of a big-scale organization, in an industry that deals with huge amounts of data. For example, you own a clothing brand. Apart from making them available on your own website, you are also outsourcing your products to third-party online stores such as Amazon, Myntra, and Flipkart; along with selling them in offline shops. To develop business strategies for your organization, you require reports such as the total revenue you earn from each point of sale, or an overview of your financial audits and payables. Imagine receiving this information in a blink of an eye. 

It goes without saying that types and formats of various data require detailed processes to be managed and optimized effectively. So, how does one exactly get the best for their business from their data treasure that’s simply sitting around? 

Who We Are

Data is God. At our heart, Integs Cloud worships data and is a problem-solver. We are committed to flawlessly automating business processes, and creating a bond between all the applications under your company’s wing. With workable answers for all data-related problems, Integs Cloud’s expertise and services basket extend to Oracle NetSuite ERP, Celigo Integration, and E-commerce solutions. 

Our greatest strength lies in our extensive knowledge, proficiency, and complete command over multiple domains. This expertise allows us to provide a futuristic business experience for our clients through pinnacle Automation and Synchronization. The result is always rewarding for your brand, through increased productivity, data-based solutions, and reduced operational costs.   

What Benefit Does Your Business Receive From Integs Cloud?

Almost all the biggest secrets to boosting your business lie in the data you already have. The truth is, you can do so much more with this data. In fact, analyzing and utilizing it in the right way can allow you to be the industry leader in your sector. 

Integs Cloud allows you to do this through our wide array of solubles:

With our 3 primary services, Oracle NetSuite ERP, Celigo Integration, and E-Commerce, some of the biggest brands have relied on us to streamline their data mechanics. Our proficient team has mastered streamlining business processes with 100+ ERP implementations under our belt with Oracle NetSuite ERP. We are an authorized Oracle NetSuite Solution Provider. Integs Cloud is also Celigo Integrations’ official partner and effectively incorporates business applications. More than anything, our diverse and experienced front runners make sure to deliver the best business and e-commerce solutions to you hassle-free. This can be seen through the whopping 300+ systems integrated that stand as stark evidence of our quality work. 

The holistic outcomes by Integs Cloud allow you to manage & track multiple resources, delve into cloud-based solutions, and experience a smooth flow of data between your departments and systems. Some of our cores are derived from innovative but reliable ideas. We also make sure to follow through, and conduct end-to-end implementations, leaving no stone unturned. For easy and comprehensible communication, Integs Cloud uses user-friendly templated methods, which are tailored to your business through our in-depth research. 

The future of business is the automation of processes. To develop and grow digitally, you must utilize the perfect technology that allows you to make the best of your business. Through our vast services and solutions, you can minimize errors and revolutionize scalability by attaining control and visibility of your whole business. With Integs Cloud, you get a chance to work smarter, not harder!

[researchinsight]

Global Integration Platform as a Service (iPaaS) Market Is Growing Worldwide 2021-2027 | SnapLogic, Inc., Scribe Software Corporation Celigo, Inc., Dell Boomi Inc.

The global Integration Platform as a Service (IPaaS) market is growing at a significant pace owing to rising adoption and awareness among enterprises globally and decreased cost of ownership. Moreover, the IPaaS market is bolstering owing to the adoption of hybrid and multi-cloud strategies that reduce the cost and optimize the workload performance cost at on-premise and cloud infrastructure. Nevertheless, the increasing demand for agility, faster deployment, and scalability will spur the growth of the IPaaS market globally.

The COVID-19 pandemic has led to the rapid adoption of cloud solutions and platforms in all organizations globally, which will drive the growth at a CAGR of 38.4% of the integrated platform as a service (IPaaS) market during the forecast period 2021-2027.

Request to get a free sample copy at https://www.vynzresearch.com/ict-media/global-ipaas-market/request-sample

Based on vertical, the BFSI sector is anticipated to have a faster CAGR during the projected period as banks are investing in IPaaS to integrate their processes and enhance cost-effectiveness. Moreover, the benefits offered by cloud-based platforms like enhanced performance, decrease total cost of ownership, real-time integration will serve as beneficial for the BFSI market.

North America dominates the IPaaS market owing to the surging investments in cloud-based applications, shifting trend towards cloud platforms. Moreover, the presence of key industry players leads to faster implementation of developed technologies and its rising adoption in the media & entertainment industry will propel the growth of the IPaaS industry in the region.

The prominent players in the IPaaS industry include SnapLogic, Inc., Scribe Software Corporation Celigo, Inc., Dell Boomi Inc., IBM Corporation, MuleSoft, Inc., Informatica Corporation, DBSync Ltd Jitterbit, Inc., and Oracle Corporation.

Source: VynZ Research

[naivelocus]

A simple high-throughput approach identifies actionable drug sensitivities in patient-derived tumor organoids

Establishment of 3D tumor models in ring format

To rapidly screen organoids, we first established a miniaturized system that allows the setup of hundreds of wells and perform assays with minimal manipulation. We adapted the geometry used to plate tumor cells in Matrigel, to generate mini-rings around the rim of the wells. This is attained by plating single-cell suspensions obtained from a cell line or a surgical specimen pre-mixed with cold Matrigel (3:4 ratio) in a ring shape around the rim in 96-well plates (Fig. 1a). Rings can be established using a single-well or multichannel pipette. Use of a robotic system or automated 96-well pipettor is theoretically feasible as long as temperature and plate positioning can be effectively controlled. The combination of small volume plated (10 µl) and surface tension holds the cells in place until the Matrigel solidifies upon incubation at 37 °C and prevents two-dimensional (2D) growth at the center of the wells. The ring configuration allows for media addition and removal so that changes of conditions or treatment addition to be easily performed by pipetting directly in the center of the well, preventing any disruption of the gel. Cancer cell lines grown in mini-ring format give rise to organized tumor organoids that recapitulate features of the original histology (Supplementary Fig. 1 and Supplementary Table 1).

Fig. 1

The mini-ring method for 3D tumor cell biology. a Schematics of the mini-ring setup. Cells are plated to form a solid thin ring as depicted in 1 and photographed in 2. The picture in 3 acquired with a cell imager shows tumor organoids growing at the periphery of the well as desired, with no invasion of the center. b Proliferation of primary tumor cells as measured by ATP release. Different seeding densities were tested and compared. This clinical sample grew and maintained the heterogeneity and histology of the original ovarian tumor, which had a high-grade serous carcinoma component (H&E left picture) and a clear cell component (H&E right picture). Scale bar, 20 µm. c Schematic of the drug-treatment experiments performed in the mini-ring setting. The pictures are representative images as acquired on different days using a Celigo cell imager. d–g Assays to monitor drug response of cell lines using the mini-ring configuration. Three drugs (ReACp53, Staurosporine, and Doxorubicin) were tested at five concentrations in triplicates for all cell lines. d ATP release assay (CellTiter-Glo 3D) readout. e,f Calcein/PI readout. e Representative image showing staining of MCF7 cells with the dyes and segmentation to quantify the different populations (live / dead). Scale bar, 400 nm. f Quantification of Calcein/PI assay for three-drug assay. g Quantification of cleaved caspase 3/7 assay. Doxorubicin was omitted due to its fluorescence overlapping with the caspase signal. For all graphs, symbols are individual replicates, bars represent the average, and error bars show SD

Similarly, we can routinely establish patient-derived tumor organoids (PDTOs) using the same geometry. As an example, Patient #1 was diagnosed with a high-grade mixed type carcinoma with both a high-grade serous component as well as a clear cell component (Supplementary Table 1 and Supplementary Fig. 2a). Cancer cells isolated from Patient #1 grown in our ring system show two distinct cytomorphologies: one group of cells have clear cytoplasm and cuboidal appearance, whereas the second group of cells organize in clusters in a columnar manner and have dense cytoplasm (Supplementary Fig. 2a). These morphologies are compatible with the two different histologies found in the original tumor, clear cell, and high-grade serous carcinoma (Supplementary Fig. 2a).

p53 is a defining marker of serous ovarian cancer, but is rarely expressed by clear cell ovarian tumors26. Both the tumor organoids and the primary cancer cells show similar p53 staining patters, with populations of p53-positive and p53-negative cells (Supplementary Fig. 2b,c). Thus, patient samples obtained at the time of surgery can proliferate in our system and maintain the heterogeneity of the original tumor as expected (Fig. 1b and Supplementary Fig. 2).

Assay optimization

Next we optimized treatment protocols and readouts for the mini-ring approach. Our standardized paradigm includes: seeding cells on day 0, establishing organoids for 2–3 days followed by two consecutive daily drug treatments, each performed by complete medium change (Fig. 1c). To demonstrate feasibility, we performed small-scale screenings testing three drugs at five different concentrations in triplicates, ReACp5317, Staurosporine27, and Doxorubicin (Fig. 1d–g, Supplementary Fig. 3–5). We optimized different readouts to adapt the method to specific research questions or instrument availability. After seeding cells in standard white plates, we performed a luminescence-based ATP assay to obtain a metabolic readout of cell status, calculate EC50, and identify cell-specific sensitivities (Fig. 1, Supplementary Figs. 3–4). Results show how the Matrigel in the mini-ring setup is thin enough to allow penetration not only of small molecules but also of higher molecular weight biologics such as peptides17. EC50s ranged between 2.5 µM (MDA-MB-468) and 10 µM (MCF7) for ReACp53, between 100 nM (MCF7) and 800 nM (PANC 03.27) for Staurosporine, and between 0.9 µM (SK-NEP) and 12 µM (MCF7) for Doxorubicin. Our measurements are in line with the Doxorubicin resistance of MCF7 cells grown in Matrigel in 3D that has been previously reported28.

We performed two consecutive treatments, which allows the drugs to not only penetrate the gel but also to reach organoids that may be bulky17. However, the assay is flexible and can be easily adapted to single treatments followed by longer incubations, multiple consecutive recurring treatments, multi-drug combinations, or other screening strategies (Supplementary Fig. 4).

We also implemented assays to quantify drug response by measuring cell viability after staining of live organoids with specific dyes followed by imaging. We optimized a calcein-release assay coupled to propidium iodide (PI) staining as well as a caspase 3/7 cleavage assay that can be readily performed after seeding the cells in standard black plates (Fig. 1e–g and Supplementary Fig. 5). For all assays, tumor organoids are stained following dispase release. After a 40 min incubation, organoids are imaged and pictures are segmented and quantified (Fig. 1e–g and Supplementary Fig. 5). All the assays are performed within the same well in which spheroids are seeded. Although the various assays we introduce are testing different aspects of cell viability and measure distinct biological events, results were mostly concordant across the methods for the three drugs tested (Fig. 1 and Supplementary Figs. 3 and 5).

Comparison of mini-ring method with traditional drop seeding

To confirm that 3D models established in mini-rings behave as those formed using traditional drop seeding methods, we directly compared the two techniques (Fig. 2). For this experiment, we seeded 5000 MCF7 cells/well either as drops or mini-rings and tested three drugs, ReACp53, Staurosporine, and Doxorubicin, in duplicates as described above. Results show that appearance of MCF7 3D spheroids (Fig. 2a) and drug sensitivities as measured by ATP assays (Fig. 2b) were undistinguishable when comparing mini-rings and drops. However, drops required individual manual aspiration and media addition, which resulted in longer processing times as no automation could be implemented.

Fig. 2

Comparison of different seeding procedures. a Bright-field images of rings and drops of MCF7 cells in Cultrex BME. Scale bar, 1 mm. b ATP assays showing identical sensitivities of mini-rings and drops to ReACp53, Staurosporine, and Doxorubicin tested at five concentrations in duplicates. Two independent experiments performed, all points shown. Bars represent the average, error bars show SD

Many other proteinaceous matrices are commercially available beside Matrigel. To confirm that other supports can be used for mini-rings, we used Cultrex BME in this experiment instead of Matrigel. Cells could be seeded as mini-rings and performance of Cultrex BME mirrored that of Matrigel (see Fig. 1d vs. Fig. 2b). In summary, different supports can be used to establish 3D models in mini-ring format and we observe no effect of mini-rings in terms of growth and drug treatment when comparing these with traditional seeding approaches.

Identification of actionable drug responses in PDTOs

A rapid functional assay to determine drug sensitivities of primary specimens can offer actionable information to help tailoring therapy to individual cancer patients3. We tested suitability of our approach to rapidly and effectively identify drug susceptibilities of three ovarian cancer samples and one high-grade serous peritoneal cancer specimen obtained from the operating room (Supplementary Table 1; Figs. 3 and 4). In all cases, ascites or tumor samples were processed and then plated as mini-rings (see Methods). To maximize the amount of information extracted from irreplaceable clinical samples, we investigated the possibility to concurrently perform multiple assays on the same plate. To do so, we first optimized the initial seeding cell number (5000 cells/well) to couple an ATP metabolic assay to 3D tumor count and total organoid area measurements. This seeding density yields a low-enough number of organoids to facilitate size distribution analysis but sufficient ATP signal to be within the dynamic range of the CaspaseGlo 3D assay. Careful consideration should be given as to whether the number of seeding cells can accurately recapitulate composition and heterogeneity of the tumor of origin. Cancer cell concentration can be reduced or augmented in our system depending on the characteristics of the tumor (Fig. 1b).

Fig. 3

Mini-ring approach to unveil drug response patterns in PDTOs. a Morphology of all PDTOs established in this study as visualized by bright-field microscopy. Morphology and 3D organization of the samples is highly variable. For instance, some of Patient #3 cells are arranged in fascicles within the Matrigel, likely representing the sarcomatous component of the tumor. Scale bar, 100 µm. b Results of kinase screening experiment for Patient #1 PDTOs. Three readouts were used for this assay: ATP quantification as measured by CellTiter-Glo 3D and organoid number or size quantification evaluated by bright-field imaging. Bright-field images were segmented and quantified using the Celigo S Imaging Cell Cytometer Software. Both organoid number and total area were evaluated for their ability to capture response to drugs. In this plot, each vertical line is one drug, all 240 tested are shown. Values are normalized to the respective vehicle controls for each method and expressed as %. AverageZ-score calculated as reported in Methods. c A representative image of the effects of the indicated drug treatments as visualized by the Celigo cell imager. Scale bar, 100 µm. d Small-scale kinase assay on Patient #1 primary PDTOs and PDX-derived cells. ATP readout. Four molecules not present in the primary screening were tested. Flavopiridol and BS-181 HCl are included as positive and negative control, respectively. t-test, **p < 0.01. e Comparison of the histology of the primary tumor with the established PDX. Scale bar: 100 µm

Fig. 4

Individualized response of PDTOs to tyrosine kinase inhibitors. a–c Results of kinase screening experiment on Patients #2–4 organoids. Each vertical line represents one of 241 tested drugs. Values are normalized to the respective vehicle controls (DMSO) for each method and expressed as %. d Expression of the multi-drug efflux protein ABCB1 in PDTOs as visualized by IHC. Patient #2 expresses very high levels of the ABC transporter. Scale bar: 60 µm. e Diagram illustrating limited overlap between the detected patterns of response identified through the mini-ring assay for all patients

For each patient sample, we seeded six 96-well plates and tested 240 protein kinase inhibitors FDA-approved or in clinical development. We tested each drug at two different concentrations (120 nM and 1 µM), for a total of 480 different conditions tested. Differently from established cancer cell lines, the number of cells obtained from surgical specimens can be limiting. As such, we opted for a two-dose focused screening, a common approach to identify potential hits. Validation can then be performed using frozen aliquots of cells that we cryopreserve after tissue processing post surgery (Supplementary Fig. 6b). However, our method can be adapted to accommodate any number of different screening designs, including concentration series (Fig. 1d–g and Supplementary Fig. 3 and 5) or multiple drug combinatorial assays.

For PDTOs, we used the same experimental paradigm optimized using cell lines (Fig. 1c). All steps (media change, drug treatment) were automated and performed in < 2 min/plate using a Beckman Coulter Biomek FX integrated into a Thermo Spinnaker robotic system. At the end of each experiment, PDTOs are first imaged in bright-field mode for organoid count/size distribution analysis followed by an ATP assay performed on the same plates. The measurements yielded high-quality data that converged on several hits, highlighting the feasibility of our approach to identify potential leads (Figs. 3 and 4).

Patient #1: high-grade mixed type carcinoma

Cells obtained from Patient #1 at the time of cytoreductive surgery were chemo-naive and the heterogeneous nature of this clear cell/high-grade serous tumor was recapitulated in the PDTOs (Table 1, Fig. 1b, and Supplementary Fig. 2). Despite aggressive debulking surgery and treatment with carboplatin and paclitaxel regimens, Patient #1 had persistent disease, never achieved complete remission, and overall survival from diagnosis was 11 months. Resistance to carboplatin was also observed in our high-throughput assay, with no significant reduction of viability observed at either 10 or 25 µM concentrations (Supplementary Fig. 6a). The organoids were however sensitive to ~6% of the protein kinase inhibitors tested (16/240), with sensitivity defined as residual cell viability ≤ 25% and average Z-score ≤ − 5 (Table 1, Supplementary Table 2, Supplementary Fig. 7a; see Methods for Z-score calculations). Patient #1’s tumor organoids responded to 58% of all cyclin-dependent kinase (CDK) inhibitors tested (7/12 total, 11 different compounds, and one, Flavopiridol, in two formulations). In particular, cells appeared highly sensitive to inhibitors hitting CDK1/2 in combination with CDK4/6 or CDK5/9 (Table 1, Fig. 3c, and Supplementary Table 3). Interestingly, CDK inhibitors have found limited applicability in ovarian cancer therapy so far29. Based on the profiles of the CDK inhibitors tested and on the response observed (Supplementary Table 3), we selected four untested molecules to assay. We anticipated that Patient #1 would not respond to Palbociclib (targeting CDK4/6) and THZ1 (CDK7), while expecting a response to JNJ-7706621 (CDK1/2/3/4/6) and AZD54338 (CDK1/2/9; Supplementary Table 3). BS-181 HCl and Flavopiridol were included as negative and positive control, respectively. Results show that organoids were not sensitive to JNJ-7706621 but had a strong response to THZ1 (Fig. 3d). Both THZ1 and BS-181 HCl specifically target CDK7. Nevertheless, Patient #1 PDTOs showed a strong response to the former but no response to the latter, which could be attributed to the different activity of the two as recently observed in breast cancer30. We detected elevated CDK7 protein expression in Patient #1 PDTOs (Supplementary Fig. 7b).

Table 1 List of molecules causing over 75% reduction in viability in PDTOs established from Patient #1’s tumor

We also attempted to validate the screening results in vivo by establishing PDXs injecting Patient #1 cells subcutaneously in NSG mice (500 K/mouse, 12 mice). However, only three mice developed PDXs over the course of 5 months. The xenografts resembled the histology of the primary tumor (Fig. 3e). To test whether the PDXs had a similar response to CDK inhibitors, we dissociated the PDX to single-cell suspension and generated organoids from one of them (Fig. 3a, d, e). The PDX-derived organoids showed an overall trend toward a reduction in sensitivity to CDKs when compared with the PDTOs. We observed a statistically significant decrease in response to 0.1 µM THZ1, and 1 µM JNJ-7706621 and AZD5438 (p < 0.01, Fig. 3d) in the PDX-derived organoid compared with the PDTOs. This is not unexpected, as human cancer cells grown in mice rapidly diverge from the tumor they were obtained from31,32.

Patient #2: platinum-resistant high-grade serous ovarian carcinoma

Patient #2 was diagnosed with progressive, platinum-resistant high-grade serous ovarian cancer and was heavily pretreated before sample procurement (Supplementary Table 1). Patient #2 PDTOs were also platinum-resistant in our system (Supplementary Fig. 6a), with no reduction of viability observed upon treating the cells with either 10 or 25 µM carboplatin. The PDTOs showed a strong response (residual cell viability ≤ 25% and average Z-score ≤ − 5) to only 0.8% of all drugs tested (2/240, Fig. 4a, Table 2, and Supplementary Fig. 7a). We validated the results by performing a dose–response study (Supplementary Fig. 6b). We exposed patient #2 organoids to eight concentrations of the two hits identified in the screening, BGT226 and Degrasyn (0, 0.05, 0.1, 0.25, 0.5, 1, 5, and 10 µM), in duplicates. We used the same experimental setup as indicated above and the EC50s calculated using the ATP results from two independent experiments confirm Patient #2’s organoid sensitivity to low concentrations of the two drugs (Supplementary Fig. 6b).

Table 2 Drug leads causing over 75% cell death in PDTOs from Patient #2, #3, and #4

Patient #2 PDTOs showed only a moderate response to our positive control, Staurosporine, a pan-kinase inhibitor with very broad activity27. The lack of response to multiple therapies observed for Patient #2 led us to hypothesize that there could be overexpression of efflux membrane proteins. Indeed, the PDTOs showed a high level of expression of ABCB1 (Fig. 4d). High expression of the ATP-dependent detox protein ABCB1 is frequently found in chemoresistant ovarian cancer cells and recurrent ovarian cancer patients’ samples, and has been correlated with poor prognosis33,34.

We found a moderate response, comparable to the effect of Staurosporine (~40% residual cell viability), to EGFR/HER2 inhibitors including Lapatinib and WZ8040 (Table 2). We could detect high expression of EGFR at the plasma membrane of the tumor cells (Supplementary Fig. 7c), as is common for platinum-resistant ovarian cancer35.

Patients #3: carcinosarcoma of the ovary

Patient #3 presented with a carcinosarcoma of the ovary, an extremely rare and aggressive ovarian tumor, which has not been fully characterized at the molecular level yet36,37 (Supplementary Table 1, Fig. 4b, Table 2, and Supplementary Fig. 7a). In our screening, the PDTOs established from this tumor responded to ~3% of all tested kinase inhibitors (7/240, residual cell viability ≤ 25%, and average Z-score ≤ − 1.5), including CDK inhibitors and phosphatidyl inositol 3-kinase (PI3K) inhibitors.

Patient #4: high-grade peritoneal carcinoma

Patient #4 was diagnosed with a high-grade peritoneal tumor and showed a response to only 0.8% of all tested drugs (2/240, Supplementary Table 1, Fig. 4c, Table 3, and Supplementary Fig. 7a and 7d). The PDTOs showed a marked response to two drugs, one pan-Akt inhibitor (GSK690693) and a PI3K/mammalian target of rapamycin (mTOR) inhibitor (BGT226), with measured cell viability ≤ 25% and average Z-score ≤ − 5. However, different from Patient #2, Patient #4 PDTOs were sensitive to Staurosporine, with only 9 ± 1% residual viability after 2 days of treatment. Protein kinase C, which is the primary target of Staurosporine, is also a secondary target of GSK69069338.

Although only 2 inhibitors caused a 75% reduction in cell viability, 11 agents caused ≥ 50% cell death (Z-score ≤ − 5). Using this cutoff, we could identify six mTOR inhibitors including Omipalisib, Apitolisib, and Sapanisertib. These constitute 30% of all the mTOR inhibitors tested, pinpointing a potential vulnerability of this pathway.

— Communications Biology - nature.com science feeds

[closeloop]

NetSuite integration is essential for modern businesses to ensure seamless data flow across all organizational levels. This enables enhanced collaboration, streamlined operations, and improved customer experiences. Integrations with platforms like Boomi, Salesforce, Shopify, HubSpot, FreshDesk, Celigo, Magento, WooCommerce, and more provide specific benefits tailored to various business needs.  Consulting with NetSuite implementation experts is crucial for tailored integration solutions.

[marketrf39-blr-blog]

Integration Platform as a Service (IPaaS) Market Size, Key Players, Investment Opportunities, Top Regions, Growth & Forecast by 2023

The report on the global Integration Platform as a Service market covers historical market trends, current market dynamics, market valuation by segmentation as well as region, country-level analysis for every segment, key player's market share analysis, competitive landscape and supply chain analysis.

Market Highlights:

The integration platform as a service market is not just growing, it is accelerating. Integration platform as a service is a cloud service that provides a platform to support applications that involve a combination of data sources and cloud-based applications and others. Dell Boomi, Inc., Informatica Corporation, MuleSoft, Inc., IBM Corporation, Oracle Corporation, and SAP SE are a few key players in the global integration platform as a service market.

Growing demand for integration platform as a service across various industry verticals is set to drive the growth of the integration platform as a service market. Increasing traction of cloud computing applications is one major factor responsible for fueling the growth of the global integration platform as a service market. Also, the extensive need for efficient processes for developing and managing enterprise applications and increasing deployment of the cloud-based application is another factor boosting the market growth.

Get a Free Sample @ https://www.marketresearchfuture.com/sample_request/5519

Major Key Players

Dell Boomi, Inc. (U.S.),

Informatica Corporation (U.S.),

MuleSoft, Inc. (U.S.),

IBM Corporation (U.S.),

Oracle Corporation (U.S.),

SAP SE (Germany),

SnapLogic, Inc. (U.S.),

Celigo, Inc. (U.S.),

Jitterbit, Inc. (U.S.),

Scribe Software Corporation (U.S.),

DBSync (U.S.),

Flowgear (South Africa).

According to Market Research Future Analysis, the Global Integration Platform as a service market is estimated to generate revenue of approximately USD 2 Billion by 2023 growing at a CAGR of 22% during the forecast period 2017-2023.

Competitive Analysis

In June 2018, TIBCO Software Inc. announced its intention to acquire Scribe Software, an innovative, cloud-based integration platform-as-a-service (iPaaS). This acquisition will enable customers to employ a single solution to address a wide range of integration scenarios, including application, data, and API projects, to interconnect everything, whether in the cloud, on-premises, or on billions of edge devices. This strategically acute acquisition enables TIBCO Cloud Integration to enter new market segments, widen its iPaaS service market, and strengthen its position globally.

The consumer electronics sub-segment of the global integration platform as a service application market is expected to grow at the highest rate during the forecast period. This growth is owing to the increasing implementation of integration platform as a service into smartphones, tablets, and wearable devices to detect gases such as alcohol, carbon monoxide, carbon dioxide, and others. Whereas, the integration platform as a service market for the oil & gas industry is expected to hold the largest market share of the market. This is owing to the increasing number of oil & gas projects and continuous increase for oil & gas industries from emerging economies.

Regional Analysis

The global integration platform as a service market is spread across Asia Pacific, North America, Europe, and Rest of the World.

It has been observed that North America is anticipated to hold the largest share of the market, whereas Asia Pacific is projected to grow at the highest rate during the forecast period. The growth of the market in North America region is attributed to technological advancements along with increased adoption of integration platform as a service application across various industry verticals. Large investments in research & development, early adoption of new & emerging technologies, coupled with the presence of a large number of players in this region also leave a colossal impact on the market.

The key reasons for the high growth rate in Asia-Pacific are increased spending on IT infrastructure, rising cloud-based applications, and also growing demand for automation of processes. Apart from these factors, growing BYOD (Bring your own device) trend, rising awareness about iPaaS among enterprises along with growing focus towards reducing the ownership cost are other factors responsible for the humungous growth observed in this region. Moreover, growing focus of the companies towards data security and data prevention coupled with growing government support in various countries in Asia-Pacific drive the iPaaS market and will continue to do so during the forecast period.

Market Segmentation

The global integration platform as a service market is segmented by service type, deployment, organization size and vertical. Based on the service type, the market is segmented into cloud service orchestration, data transformation, API management, data integration, real-time monitoring & integration, business to business (B2B) & cloud integration, application integration, training & consulting and support & maintenance. Based on the deployment, the market is segmented into the public cloud, private cloud, and hybrid cloud. Based on the organization size, the market is segmented into SMEs and large enterprises. Whereas, based on the vertical, the market is segmented into BFSI, healthcare, manufacturing, education, media & entertainment, IT & telecommunication, government, and others.

Browse Complete Report @ https://www.marketresearchfuture.com/reports/integration-platform-as-a-service-market-5519

Intended Audience

Technology Investors

Research/Consultancy firms

Government Bodies

Third-party vendors

Application Design & Development Service Providers

System Integrators

Training & Education Service Providers

Data Integration Service Providers

Managed Service Providers

Data Quality Service Providers

LIST OF TABLES

Table 1 Global Integration Platform as a Service Market: By Region, 2017-2023

Table 2 North America Integration Platform as a Service Market: By Country, 2017-2023

Table 3 Europe Integration Platform as a Service Market: By Country, 2017-2023

Table 4 Asia-Pacific Integration Platform as a Service Market: By Country, 2017-2023

Table 5 Middle East & Africa Integration Platform as a Service Market: By Country, 2017-2023

Table 6 Latin America Integration Platform as a Service Market: By Country, 2017-2023

Continued………

LIST OF FIGURES

FIGURE 1 Global Integration Platform as a Service Market Segmentation

FIGURE 2 Forecast Methodology

FIGURE 3 Five Forces Analysis of Global Integration Platform as a Service Market

FIGURE 4 Value Chain of Global Integration Platform as a Service Market

Continued………

About Market Research Future:

At Market Research Future (MRFR), we enable our customers to unravel the complexity of various industries through our Cooked Research Report (CRR), Half-Cooked Research Reports (HCRR), Raw Research Reports (3R), Continuous-Feed Research (CFR), and Market Research & Consulting Services.

MRFR team have supreme objective to provide the optimum quality market research and intelligence services to our clients. Our market research studies by products, services, technologies, applications, end users, and market players for global, regional, and country level market segments, enable our clients to see more, know more, and do more, which help to answer all their most important questions.

Contact:                                                                                    

Market Research Future

+1 646 845 9312

Email: sales@marketresearchfuture.com

[technosip]

How To Choose The Right NetSuite Integration Partner?

Advancement in technologies has played a significant role in transforming how businesses used to operate earlier. All the shapes and sizes of businesses are revolutionizing from the old approach to a new edge digital space, where convenience is being given the highest priority to carry out all the business processes under a single cloud system. As a result, a need for ERP Implementation emerges that can meet the need for the self-automation of the enterprises.

Hundreds of organizations provide ERP Implementation services, and choosing the right Netsuite integration partner has become even more challenging.

Although Netsuite provides operational and financial performance visibility, there are still several factors that require special attention when choosing the right NetSuite integration partner. Around 75% of ERP Implementation fails due to the wrong selection of the integration partner. You have landed on the right page if you are looking for assistance with NetSuite licensing, NetSuite implementation services, and NetSuite Partner with SuiteCommerce experience.

Why Choose NetSuite?

NetSuite is world’s best management software suite known for providing a single web-based platform for multiple business processes like Customer Relationship Management, Enterprise Resource Planning, Human Resources Management Software, and automation for Professional Services and eCommerce.

How To Choose Right Netsuite Integration Partner

Once you have decided to go with Netsuite as your ERP software for your business, you have to consider the below points for selecting the right partner.

While selecting the Netsuite Integration Partner, choose the one with specific industry experience per your custom tailor business requirements. Manufacturing or a software company can have Netsuite ERP software, but the business operations are entirely different. Both will have altogether different integrations. So it is always recommended to find a partner who has specific industry-rich experience similar to your industry.

ERP implementation is crucial for every business, including money, time, resources, stakeholders, and profitability. So, it is always better to fix the deal with licensed service providers only.

Netsuite is an outstanding ERP software with many advanced functionalities, which will lead your organization towards success. Moreover, finding the right Netsuite integration partner like Technosip will ensure successful implementation and enable your business to succeed.