#felix bergström

[chrancecriber]

Antenne Vorarlberg Chillout Lounge (August 19, 2023)

23:58 Elderbrook - I Need You 23:53 Afterlife - How Does It Feel (Original Mix) 23:50 Armin Van Buuren Feat. Rbvln - Weight Of The World (Feat. Rbvln) 23:45 Thomas Lemmer & Andreas Bach - Embracing Love 23:41 Depeche Mode - Freelove 23:38 Zoe - C'est La Vie 23:34 Airstream One - Southern Light 23:30 Winona Oak & Robin Schulz - Oxygen 23:23 Blank & Jones - White Light 23:17 Groovecatcher - Angel Of Nature 23:15 Alok & Timmy Trumpet - Underwater Love (La Vision Remix) 23:04 Monkey Safari - Hi Life (Cheeky Bold Cover) 22:59 Massive Attack - Protection 22:55 Sound Nomaden - The Morning After 22:51 Kygo & Sasha Sloan - I'll Wait 22:43 Tactful - No Fear 22:40 Bolier & Arman Cekin - Fade Away (Feat. Rhi'n'b) 22:36 Blank & Jones Feat. Zoe Durrant - Adios Ayer 22:28 Chaim Feat. Meital De Razon - Love Rehab 22:25 Klingande, Wrabel - Big Love 22:20 Jacob Gurevitsch - Lovers In Paris 22:17 Filatov & Karas - Au Au 22:13 Tinlicker Feat. Nathan Nicholson - Be Here And Now 22:07 Hippiehaus - Galaxy 22:04 Lost Frequencies, Zonderling & Kelvin Jones - Love To Go 21:56 Martin Roth - An Analog Guy In A Digital World 21:50 Bliss - End Titles 21:47 Laniia - Fireflies 21:42 Enui - Adieu (Arielle Lb Remix) 21:37 Roger Shah, Feel, Zara Taylor - One Life (Pedro Del Mar & R.i.b Chillout Remix) 21:32 Glide - Y Môr 21:29 Cosmic Soul & Tom Novy - Like A Dream 21:27 Sylvering - Is There Anybody Out There 21:18 Blond:ish Feat. Bahramji - Omnipresent 21:13 Schiller Feat. Mia Bergström - Playing With Madness 21:07 Banderas - This Is Your Life (Easy Life Mix) 21:02 Christopher Von Deylen - Free 20:58 Karen Gibson Roc - Painted Room 20:51 Rodriguez Jr. Feat. Liset Alea - What Is Real 20:49 Felix Jaehn & The Stickmen Project Feat. Calum Scott - Rain In Ibiza 20:45 Be Svendsen - Drop The Gun 20:39 Röyksopp & Jamie Irrepressible - The Next Day (Mind Against Remix) 20:36 Ck West - Aldebaran 2021 20:32 Smoke City - Underwater Love 20:28 Klangkarussel & Poppy Baskcomb - This Love 20:24 Chicane Feat. Bryan Adams - Don't Give Up 20:18 Kruder & Dorfmeister - Black Baby 20:14 Clément Leroux - Memories 20:11 Kygo Feat. Kodaline - Raging 20:05 Nora En Pure - Thermal (Extended Mix) 20:01 Julian Wassermann - Painfully 19:56 Schiller - Zukunft 19:49 Blond:ish Feat. Shawni - Wizard Of Love 19:47 Vievie - Blue Island 19:40 Sweed Feat. Janana - Finally (Holter & Mogyoro Remix) 19:37 Magnofield - Lupino 19:33 Robin Schulz - Above The Clouds 19:29 Aromabar - Renegade 19:26 Lost Frequencies & Elley Duhé - Back To You 19:21 Pete Tong & Tale Of Us Feat. Jules Buckley - Time 19:14 Depeche Mode - Waiting For The Night 19:12 Chaël Feat Kaii - Don't Speak 19:08 Frank & Friedrich Feat. Duncan Woods - Coming Home 19:05 Vize & Tom Gregory - Never Let Me Down 18:59 Nora En Pure - Cognitive Fadings (Club Mix) 18:55 Moby - The Sky Is Broken 18:52 Edx - Ecletric (Mixed) 18:49 Sono - Keep Control (Artbat Remix Edit) 18:41 Framewerk - Electric Religion 18:38 Hanns Feat. Lu - Chemistry 18:35 Kygo & Tina Turner - What's Love Got To Do With It 18:31 Air - You Make It Easy 18:23 Armin Van Buuren & Avira Feat. Sam Martin - Mask 18:19 Valante - Rissa 18:12 Chris Zippel - Mirror Dawn 18:07 Three Drives On A Vinyl - Greece 2000 (Sebastian Davidson & Melosense Remix) 18:03 Thievery Corporation - It Takes A Thief 17:58 Schiller - White Nights (Don't Let Me Go) 17:55 Morgan Page Feat. Lissie - Firewalk 17:52 Blank & Jones - Fall In Love 17:47 Nora En Pure - Trailblazer (Club Mix) 17:43 Moli - Cloud No9 (Montmartre Remix) 17:39 Stj, Clifford Borg - Eco Ballad 17:35 Ac Venture - Rain In Spain (Roberto Sol Remix) 17:30 Worakls - Caprice 17:26 Patrick Baker - Call Me Up (Original Mix) 17:21 Goa Foundation - (I Just) Died In Your Arms Tonight 17:14 Hraach - After Dark 17:09 Remady & Manu-l - Another Day In Paradise 17:06 Robin Schulz & Alle Farben & Israel Kamakawiwo'ole - Somewhere Over The Rainbow / What A Wonderful World 17:03 Sam Feldt - Show Me Love (Original Mix) 16:58 Schiller Feat. Jael - Tired (Live) 16:54 Schiller - Once Upon A Time (Cahill Remix) 16:51 Sal De Sol - Another Chance (Single Mix) 16:47 Blank & Jones - Sunny (Summer Vibe Mix) 16:44 Thomas Gold Feat. Bright Sparks - Seventeen 16:41 Tom Walker - Just You And I 16:35 Twocolors - Together 16:32 Trinix - Soweto 16:26 Alle Farben - Sonoro (2018 Rework) 16:24 Carstn, Jason Walker - Could You Love Me (Munich Monstrs Remix) 16:20 Sum Wave - Goodbye Earth 16:16 Alan Walker Feat. Anthony Keyrous & Henri Purnell Feat. Romy Wave - Alone (Remix) 16:13 Klangkarussell And Givven - Follow 16:10 Worm Is Green - Electron John 16:07 Rene Rodrigezz & Tristan Henry - Let Me Go 16:03 The Ocean Piano - Piano Mi Camino (Blue Wave Mix) 15:59 Schiller - Lichtwerk 15:56 Sans Souci - Condor 15:52 Panama, Satin Jackets - The Future 15:47 Tibet Project - Tibet (A Passage To ...) 15:41 Beyhude - Terso 15:37 P. Lion - Happy Children (Special Remastered) 15:29 Nor Elle - Silent Storm 15:24 Lstn - Floral Decor 15:21 Milkwish - From The Earth To The Moon 15:16 Sise - The Rain (Where Do I Begin) 15:13 Sum Wave - Backyard Stories 15:06 Richard Grey - Need Your Lovin (Murjd Remix) 15:03 Nihoni - After Sun 14:56 Consolidation Feat. Moguai - Ode To Joy 14:54 Meduza & Becky Hill X Goodboys - Lose Control 14:50 Younotus Feat. Chris Gelbuda - When I Think About You 14:47 Above & Beyond - Is It Love? (1001) (Original Mix) 14:42 Schiller & Giorgio Moroder - Lichtjahre 14:38 Schiller - Summer In Berlin 14:36 Mila Feat. Uwe Worlitzer - Teil Von Mir 14:32 Gary B. - Lead Me Home 14:29 Klangperlenspiel - Fraction Of Your Love 14:26 Atb & Topic - Your Love (9pm) 14:21 Glenn Main - Message To Spain 14:15 Beyhude - Rüzgar 14:12 Lucy Neville - Fall At Your Feet 14:09 Milk & Sugar Feat. John Paul Young - Love Is In The Air 14:05 Eli & Fur - Come Back Around 14:01 The Chill Out Orchestra - Wish You Were Here 13:58 The Alan Parsons Project - The Turn Of A Friendly Card 13:55 R3hab & Marnik - Candyman 13:51 Deeperise Feat. Jabbar - One By One 13:48 Armin Van Buuren & Avira - Illusion (Mixed) 13:43 Elderbrook & Bob Moses - Inner Light 13:37 Fous De La Mer - Waiting For The Sun 13:33 Golden Tone Radio - Glück 13:30 Blank & Jones Feat. Zoe Durrant - Erase Rewind 13:24 Under Pressure - Near The Ocean 13:21 Loud Luxury - Cold Feet 13:14 Armen Miran - Precious Story 13:10 Schiller & Tricia Mcteague - Guardian Angel 13:07 Gibbs & Code X - Close To Your Heart 13:04 Duke Dumont Feat. Jax Jones - I Got U 12:57 Hraach & Armen Miran - Nowhere 12:53 Schiller - Free The Dragon 12:49 Robin Schulz Feat. Graham Candy - 4 Life (Original Mix) 12:45 Nora En Pure - World Of Rules 12:41 Kid Massive, Yuji Ono, Dtale - Pray (Wolf Krew Remix) 12:38 Clyb Foster - How Deep Is Your Love 12:34 Passenger 10 - Serving The World 12:31 Sam Feldt Feat. Lateshift - The Riddle 12:26 Melounge - Too Much Sugar 12:24 Srtw & Mave Feat. Sønlille - Last Train Home 12:19 Moby - Everything That Rises 12:16 Robin Schulz Feat. Alida - In Your Eyes 12:11 Avira & Kiko Franco Feat. Nathan Nicholson) - Ocean 12:09 Jubel Feat. Neimy - Dancing In The Moonlight 12:06 Bernward Koch - Flowing Colors 12:00 Anrey - The Forgotten (Extended Mix) 11:55 Les Negresses Vertes - Face A La Mer 11:49 Christopher Von Deylen - Euphoria 11:44 Victoriya - Nothing Remains 11:41 Lilly Wood & The Prick And Robin Schulz - Prayer In C 11:37 Lstn - Sïstër 11:31 Colyn - Unstable Gravity Alert 11:27 Quantic - Painting Silhouettes (Original Mix) 11:23 Sons Of Maria - Elevate 11:19 Solaris Navis - Blissful Memories 11:15 Basixx - Stay In Your Sunlight 11:12 Loud Luxury And Frank Walker Feat. Stephen Puth - Like Gold 11:08 Aguaflames - Moiman 11:05 Sans Souci - Take My Breath Away (Original Mix) 11:01 Neptune & Moonnight - I Need A New Love (Original Mix) 10:57 Cristian Marchi Feat. Block - Baker Street 10:53 Above & Beyond Feat. Zoe Johnston - Treasure 10:51 The Holy Santa Barbara Feat. Madugo - The Sailor Song 10:46 Black Zone Ensemble - Bubbles 10:42 Nora En Pure - Sign Of The Times 10:39 Schiller - Midnight In Shiraz 10:35 Blank & Jones - Wyb (Deeper) 10:32 Kygo With Avicii & Sandro Cavazza - Forever Yours (Tribute) 10:25 Marcel - Departure 10:18 Avira & Diana Miro - The Worship (Mark Knight Extended) 10:13 Fritz Kalkbrenner - Good Things 10:10 James Blunt - Cold 10:06 Dvine - Unknown Reality 10:03 Agatino Romero - I'm Feeling For You 09:59 Moist - Far Beyond The Endless (Original Mix) 09:56 Mike Candys - Sky (Club Mix) 09:49 Röyksopp Feat. Susanne Sundførd - Oh, Lover 09:46 Mario & Vidis Feat. Jazzu - I'll Be Gone 09:43 Bolier - Another Blue 09:40 Kush Kush & Sickmellow Feat. Kazhi - Blacklight 09:36 Moby - Porcelain (Arty Remix) 09:33 Blank & Jones - Swept Away 09:28 Depeche Mode - Useless 09:24 Ec Twins, Oda Loves You - Wonderful Life 09:20 Olga Scheps - How Much Is The Fish? 09:15 La Vita - Saxual Seduction 09:10 Robin Schulz - Moonlit Sky (With The Void Pacific Choir) 09:05 Exstra - Comet (Extended Mix) 09:01 Black Coffee & David Guetta Feat. Delila Montagu - Drive 08:56 Jens Buchert - Cocoon 08:53 Undressd - Forever Young 08:45 Andre Rizo - Hang 08:42 Shouse - Won't Forget You 08:39 Vamero & Lizot - Bleeding Love 08:32 Francesco Rossi - Paper Aeroplane 08:28 Nora En Pure - All I Need 08:25 Thievery Corporation Feat. Shana Halligan - Depth Of My Soul 08:22 Dimitri Vegas - Pull Me Closer 08:14 Maxim Lany - Riding The Wave (Extended Mix) 08:11 Marit Larsen - I Don't Want To Talk About It (Nelsaan & Matoma Tropical Remix) 08:07 Kungs Feat. Jhart - Dopamine 08:05 Famba Feat. Brando & Mkla - Games We Play 08:02 Martin Jensen - Solo Dance 07:58 Klangperlenspiel & Puzzls - Kyoto (Wish You'd Move On) 07:55 Robin Schulz & David Guetta - On Repeat 07:51 The Alan Parsons Project - Lucifer 07:48 Gamper & Dadoni - Gimme! Gimme! Gimme! 07:45 Sam Feldt & Sam Fischer - Pick Me Up (Vavo Remix) 07:38 Worakls - Elea (Original Mix) 07:33 Lazy Hammbock - Surround Me 07:30 Kygo Feat. Ellie Goulding - First Time 07:25 Two Lanes - Pièces Froides: Ii. Danses De Travers 07:22 Gamper & Dadoni Feat. Joe Jury - Satellites 07:19 Bossasonic - Wicked Game 07:16 Zaz - Demain C'est Toi 07:09 Bay Area - Dolphin Rider (Pianodreamsession) 07:04 Mahoroba - Soft Breeze (On Air Mix) 06:59 Thomas Lemmer & Andreas Bach - Sweet Lullaby 06:55 Joachim Pastor Feat. Nathan Nicholson - Saint Louis 06:50 Eelke Kleijn - Mojo's Tale 06:48 Minelli, Filatov & Karas Remi - Rampampam 06:45 York - On The Beach (Kryder & Jenjammin Sax Edit) 06:41 Stephane De Lucia - Trippin 06:34 Soul Button - Circadian Rhythm (Hraach Remix) 06:30 Wankelmut & Emma Louise - My Head Is A Jungle 06:27 Rosa Linn - Snap 06:23 Alina Baraz & Galimatias - Fantasy (Felix Jaehn Remix) 06:17 Alex Cortiz - Enter The Matrix 06:14 Gestört Aber Geil & Anna Grey - Thank You 06:11 Armin Van Buuren & Garibay - Phone Down 06:05 Danijel Kostic - Vinternatt (Club Mix) 05:58 John Kah - Carina (Enui Remix) 05:51 Worakls - By The Brook 05:49 Lost Frequencies Feat. James Blunt - Melody 05:42 Dale Anderson Feat. Anil Chawla - Pimento Grove 05:35 True & Berger - Imprint Of Pleasure 05:30 Eli Kazah - Return Home 05:26 Gardenstate & Bien - The Best Part 05:23 Sono - Twist In My Sobriety (Sans Souci Remix Edit) 05:14 Jan Blomqvist - Empty Floor 05:11 Nto (Fr) Feat. Sofiane Pamart - Invisible (Piano Version) 05:08 Blank & Jones Feat. Coralie Clément - Jardin D'hiver 05:05 Steve Forest, Te Pai - Never Gonna Give You Up 05:02 Alex Zind Feat. Lisa Schwab - Cruel Summer 04:55 A Forest Mighty Black - Rebirth 04:51 Cats On Bricks Feat. Zach Alwin - Planes Over Ushuaia 04:47 Sofi Tukker X Mahmut Orhan - Forgive Me 04:42 James Bright - Sarabande 04:40 Nightcall X Henri Purnell Feat. Eke - When The Morning Breaks 04:36 Daniel Steidtmann - Pigeon Lake 04:33 Filous Feat. James Hersey - How Hard I Try 04:27 Airstream - Your Tears (Del Mar Mix) 04:25 Nimus - Wasted Heart 04:20 Blank & Jones Feat. Zoe Durrant - One Evening (Lofi Selection) 04:16 Lstn - Thoughts 04:10 Fous De La Mer - Esse Sonho 04:04 Jean-michel Jarre - Equinoxe, Pt. 4 04:00 Above & Beyond - Out Of Time (Original Mix) 03:56 Kygo Feat. Parson James - Stole The Show 03:54 Digital Camel - Shine Bright 03:47 Monolink - Otherside (Club Mix) 03:42 Moca - Kleine Träumerei 03:40 Avian Grays & Azteck - Endlessly 03:32 Garlington - Falling To Pieces (Extended Mix) 03:26 Coastline - Adriatic Sea (Milews Remix) 03:22 Audien - Blue 03:17 Nora En Pure Feat. Ashibah - We Found Love 03:14 Tomas Skyldeberg - Chillin With You 03:10 Kryder & Natalie Shay - Rapture 03:04 Deep-dive-corp. - Lucsus 03:02 Christopher Von Deylen - Arco Iris 02:56 Shkoon Feat. Fruiterama - Napauken 02:51 Croquet Club - Awake 02:47 Above & Beyond Feat. Zoe Johnston - We're All We Need 02:44 Tiësto & Ty Dolla $ign - The Business, Pt. Ii 02:39 Mic Max - Como El Viento 02:31 Atb - No Fate 02:29 Thrdl!fe & Sleepwalkrs - Outta My Head 02:25 Peter Ries - Hold Me (The Force Radio Mix) 02:19 Röyksopp Feat. Susanne Sundfør - If You Want Me 02:12 Tapesh And Dayne S - How I Do (Original Mix) 02:08 Stepha Schweiger - When I Was A Bird 02:05 Möwe - Bad Intentions 02:01 Shaun Feat. Conor Maynard - Way Back Home 01:58 Chris Avedon - The Letter 01:55 Mount & Illian - Fool 01:48 4tunes - Helen 01:40 Blank & Jones - California Sunset 01:37 Shaun Frank & Takis Feat. Shells - Don't Say I Love You 01:33 Schiller - Der Tag...du Bist Erwacht (Mit Jette Von Roth) 01:31 Above & Beyond - Quieter Is Louder (Original Mix) 01:29 Leony - Faded Love (Noøn Remix) 01:25 Lenny Ibizarre - The Rain 01:22 Alok Feat. John Martin - Wherever You Go 01:19 State Of Sound - Wake Up Where You Are 01:16 Vize & Leony - Dolly Song (Devil's Cup) 01:13 Dj Antoine Feat. Chanin & Jona Xx - Dancing In Tulum 01:08 Riccardo Eberspacher - Sunetul De Seara 01:06 Cyrillic Feat. Lara - Zero Gravitation 01:02 Robert Manos - Silver 00:58 First Aid Kit - My Silver Lining 00:56 Vinai - Hide Away 00:49 The Last Atlant - Twin Of The Sun 00:46 Unclubbed, Zoe Durrant - Need To Feel Loved (Original Mix) 00:42 Gibbs - Waiting For Lonely 00:38 Lstn - Sky & Sand 00:34 Ilo - Soleil D'hiver 00:27 Beyhude - Alabora 00:22 Flamingo Star - Lost In Music 00:16 Blank & Jones - Coh 00:10 Armen Miran - Nani Jan 00:07 Sagi Rei - Rhythm Is A Dancer 00:01 Sans Souci - Venice

[fekkovich]

Industrial

[ariendiel]

Yes please to the list of last names you use ❤️ thanks

Of course! Here you go 💋 Some I'm missing, but feel free to come with suggestions

LITG SURNAMES

Bobby McKenzie

Chelsea Edwards

Felix Brimble

Gary Rennell

Hannah Griffiths (although I have mostly used Perkins)

Henrik Åkerblom (or Bergström, or both)

Hope Adzaho

Ibrahim Chapman

Jakub Zabinski

Jo Evans

Kassam Zeroual

Lottie Crawford

Lucas Koh

Marisol Trujillo

Noah Buan Alexander

Priya Patel

Shannon Cullen

[ravenadottir]

saw ur birthday post for the islanders and i was wondering if you could also do the years they would be born in?

ooh ok, i never include the year but i guess some of them could have confusing birthdays

let's consider season 2 happened in 2019, therefor it needs to be the year to base this estimation. and bobby was 26 in my country, so there'll be two different years.

° bobby mckenzie, may 22, 1993/1995 - gemini

° carl gallagher, february 27, 1990 - pisces

° chelsea collins, december 5, 1995 - sagittarius

° elijah, august 9, 1991 - leo

° elisa walker, january 12, 1997 - capricorn

° felix jones, march 30, 1998 - aries

° gary rennell, december 27, 1995 - capricorn

° graham harris, january 29, 1996 - aquarius

° hannah griffiths, march 18, 1996 - pisces

° henrik bergström, november 23, 1995 - sagittarius

° hope edwards, january 2, 1993 - capricorn

° ibrahim wilson, march 11, 1997 - pisces

° jakub zabinski, september 8, 1993 - virgo

° kassam mansouri, october 26, 1992 - scorpio

° lottie taylor, november 1, 1994 - scorpio

° lucas koh, april 8, 1992 - aries

° marisol fernandez, october 5, 1994 - libra

° noah, may 15, 1995 - taurus

° priya hinduja, august 9, 1989 - leo

° rocco martin, july 18, 1997 - cancer

° shannon o’malley, february 10, 1995 - aquarius

° tai kahu, march 16, 1993 - pisces (because s3 came out in 2020)

[deuchess]

What do you think the s2 islanders' surnames are?

this has been hanging out in my inbox for a bit now, sorry. got some help from @ariendiel with Noah and Henrik <3

i honestly just ended up picking what i thought sounded good, i’m only happy with like four of these but this ask has been in my inbox for way too long now

Hope Williams

Lottie (Charlotte) Miller

Marisol Suarez

Hannah Perkins

Noah Alexander Buan

Ibrahim Chapman

Rocco (Rodrick?) Wilson

Priya Patel

Henrik Åkerblom Bergström

Chelsea Edwards

Arjun Khatri

Elijah Harris

Carl O’Sullivan

Felix Burke

Graham O’HOY Porter

Kassam Maleek

Shannon Cullen

Blake Thomson

Jo Evans

Elisa Davies

[goalhofer]

2020 Olympics Sweden Roster

Archery

Christine Bjerendal (Lindome)

Athletics

Vidar Johansson (Öjersjö)

Kalle Berglund (Jämshög)

Emil Blomberg (Järfälla)

Perseus Ibáñez-Gustavsson (Växjö)

Andreas Kramer (Sävedalens)

Simon Sundström (Stockholm)

Kim Amb (Solna)

Armand Duplantis (Lafayette, Louisiana)

Thobias Montler (Malmö)

Wictor Petersson (Malmö)

Simon Pettersson (Stockholm)

Daniel Ståhl (Solna)

Meraf Bahta-Ogbagaber (Stockholm)

Sarah Lahti (Klippan)

Carolina Wikström (Roslagen)

Angelica Bengtsson (Väckelsång)

Erika Kinsey (Nälden)

Sara Meijer (Göteborg)

Maja Nilsson (Stockholm)

Fanny Roos (Ljungby)

Khadi Sagnia (Helsingborg)

Badminton

Felix Burestedt (Vellinge)

Boxing

Adam Chartoi (Stockholm)

Agnes Alexiusson (Värnamo) Canoeing

Erik Holmer (Nyköping)

Petter Menning-Öström (Vaxholm)

Linnea Stensils (Vaxholm)

Cycling

Jenny Rissveds (Falun)

Diving

Emma Gullstrand (Stockholm)

Equestrian

Sven Svennerstål (Stockholm)

Carl Fredricson (Flen)

Rolf-Göran Bengtsson (Lund)

Peder Fredricson (Flen)

Henrik Von Eckermann (Nyköping)

Louise Romeike (Stockholm)

Therese Viklund (Stockholm)

Therese Nilshagen (Lodbergen, Germany)

Antonia Ramel (Bettna)

Juliette Ramel (Bettna)

Malin Barijard-Johnsson (Söderköping)

Sara Algotsson-Ostholt (Rockneby)

Soccer

Rut Lindahl (Katrineholm)

Jonna Andersson (Mjölby)

Emma Kullberg (Umeå)

Hanna Glas (Sundsvall)

Hanna Bennison (Lomma)

Magdalena Eriksson (Stockholm)

Madelen Janogy (Falköping)

Lina Hurtig (Avesta)

Kosovare Asllani (Kristianstad)

Eva Jakobsson (Örnsköldsvik)

Emma Blackstenius (Vadstena)

Jennifer Falk (Göteborg)

Amanda Ilestedt (Sölvesborg)

Gun Björn (Uppsala)

Olivia Schough (Vanered)

Ingrid Angeldal (Uppsala)

Sara Seger (Helsingborg)

Fridolina Rolfö (Kungsbacka)

Anna Anvegård (Bredaryd)

Julia Roddar (Falun)

Rebecka Blomqvist (Göteborg)

Zećira Mušović (Skåne)

Golf

Alex Norén (Stockholm)

Henrik Norlander (Augusta, Georgia)

Anna Nordqvist (Orlando, Florida)

Magdalene Sagström (Orlando, Florida)

Gymnastics

David Rumbutis (Älvsbyn)

Jonna Alderteg (Eskilstuna)

Handball

Jonathan Carlsbogård (Göteborg)

Max Darj (Göteborg)

Niclas Ekberg (Ystad)

Daniel Pettersson (Eskilstuna)

Andreas Palicka (Lund)

Hampus Wanne (Göteborg)

Mikael Aggefors (Stockholm)

Fredric Pettersson (Jönköping)

Felix Claar (Norrköping)

Lucas Pellas (Stockholm)

Albin Lagergren (Varberg)

Jim Gottridsson (Ystad)

Oscar Sunnefeldt (Mölndal)

Lukas Sandell (Reslöv)

Anton Lindskog (Kristianstad)

Johanna Bundsen (Uddevalla)

Carin Strömberg (Nacka)

Linn Blohm (Stockholm)

Jamina Roberts (Göteborg)

Melissa Petrén (Huddinge)

Mathilda Lundström (Stockholm)

Johanna Westberg (Nacka)

Jessica Ryde (Lund)

Sara Dano (Göteborg)

Anna Lagerquist (Lund)

Emma Lindqvist (Helsingborg)

Nathalie Hagman (Farsta)

Kristin Thorleifsdóttir (Stockholm)

Elin Hansson (Nacka)

Jenny Carlson (Göteborg)

Judo

Tommy Macias (Stockholm)

Robin Pacek (Stockholm)

Marcus Nyman (Tullinge)

Anna Bernholm (Älvsbacka)

Rowing

Lovisa Claesson (Jönköping)

Sailing

Jesper Stålheim (Karlstad)

Emil Järudd (Stockholm)

Max Salminen (Lund)

Fredrik Bergström (Onsala)

Anton Dahlberg (Växjö)

Olivia Bergström (Göteborg)

Lovisa Karlsson (Stockholm)

Cecilia Jonsson (Stockholm)

Josefin Olsson (Nyköping)

Shooting

Stefan Nilsson (Naglarp)

Skateboarding

Oskar Rozenberg-Hallberg (Malmö)

Swimming

Robin Hanson (Stockholm)

Victor Johansson (Nässjö)

Erik Persson (Kungsbacka)

Björn Seeliger (Södertälje)

Michelle Coleman (Vallentuna)

Emelie Fast (Solna)

Louise Hansson (Ramlösa)

Sophie Hansson (Ramlösa)

Sarah Sjöström (Salem)

Sara Junevik (Leksand)

Table Tennis

Anton Källberg (Stockholm)

Mattias Falck-Karlsson (Karlskrona)

Kristian Karlsson (Trollhättan)

Linda Bergström (Stockholm)

Christina Källberg (Stockholm)

Tennis

Rebecca Peterson (Stockholm)

Weightlifting

Patricia Strenius (Karlskrona)

Wrestling

Alex Kessidis-Bjurberg (Stockholm)

Sofia Mattsson (Gällivare)

Henna Johansson (Gällivare)

[legendsmagazine]

The 2021 Summerscape Festival is taking place in Dubai later this month, and Summerscape has announced some of their all-star lineup including headliners Luca Romano, Elsa Bergström, Penny Lane, Kylie Blue, and Essence Woods. View the full lineup (so far) below. It has been announced that there are a few more performers yet to be named. (bold notes a headliner).

Day 1 - Friday

Poppy Blackwell

Youngblood

Ezra Lutz

Day 2 - Saturday

Not A Phase

Hudson Grey

Olivia Marie

Mathilde Faulkner

Camisado

Day 3 - Sunday

Ryan Price

Essence Woods

Penny Lane

Day 4 - Friday

King

Lennon

Elsa Bergström

Day 5 - Saturday

Chloe Zuicq

Callan Duffy

Felix Zuicq

Luca Romano

Day 6 - Sunday

Mia Harper

Amar

Maia Karim

WLDCRD

Kylie Blue

[amyfreelancemodel]

Felix Bergström is one of my favourite photographers. He is so professional and laid back, plus he takes very good photos! This is from the first session we did together (it should have been before the one with Elanthi, oops!), he came up from Gotland to visit the frozen north :). This series is titled “Waiting”.

Felix’ Tumblr can be found here: https://fekkovich.tumblr.com/ MUA/Stylist is DahliaDee: https://www.instagram.com/officialdahliadee/

[juniperpublishers-ttsr]

Revisiting Aspirin, Paracetamol and Ibuprofen: Discovery of Synthetic Procedures and Mode of Actions

Abstract

In this article, we will outline the historical background of the popular medicines Aspirin, Paracetamol and Ibuprofen which have been widely used for decades for their desired therapeutic effects as Analgesics, Antipyretics and Anti-inflammatory agents. We will discuss the synthetic procedures and mechanism of actions of these well-known drugs, achieved through systematic research on medicinal chemistry as well as cellular biology and pharmacology.

Keywords:Aspirin; Paracetamol; Ibuprofen; Discovery; Metabolism

    Introduction

By the end of the nineteenth century, scientific approach towards development of medicine made it possible to isolate drugs like Quinine, Ipecacuanha, and Aspirin etc. which were mainly derivatives of Natural Products. In modern times, screening of synthetic drug and lead chemical identification is an extremely complex process which requires active participation of disciplines like organic chemistry, biochemistry, microbiology, physiology, pharmacology. Even after discovery, it takes ages for the candidate drug to come for marketing. It has often been seen that establishment of proper mechanism of action of therapeutic effects involves collaborations of different research groups, from different countries, even from different time periods. In this article, we will outline the developmental process of the popular medicines Aspirin, Paracetamol and Ibuprofen which have been widely used for decades for their desired therapeutic effects as Analgesics, Antipyretics and Anti-inflammatory agents. The terms Analgesics and Analgetic drugs are often used interchangeably to describe a diverse group of pain medications. Antipyretics are the drugs that lower body temperature increased by infections or other diseases but have no effect on normal body temperature. Anti-inflammatory agents are the drugs used to diminish or reduce inflammation and pain associated with it. Here we will highlight the discovery of the laboratory synthetic procedures and mechanism of actions of these well-known drugs.

    Aspirin

Willow bark extract was recognised as folk medicine from the mid-eighteenth century for treatment of fever and pain. Salicylic acid derived from willow bark is one of the oldest analgesics. However, its use can cause gastric irritation and bleeding due to the free phenolic group. This is overcome by masking the phenol as an ester. The compound acetylsalicylic acid known as Aspirin was tested and introduced into medicine by Bayer in Germany in the late 1890s. Heinrich Dreser, Arthur Eichengrün and Felix Hoffmann are recognised as pioneers in the development of acetylsalicylic acid as the drug Aspirin. Bayer’s brand name, Aspirin was named by taking a from acetyl and spirin, comes from an old name for salicylic or spiric acid, derived from its natural source of spirea plants. Synthetically, Salicylic acid is converted to its prodrug Aspirin by acetylation of the phenolic hydroxy group. In human body, Aspirin is mainly converted to salicylic acid by esterases after absorption from the GI tract. This reduces the degree of stomach irritation because lesser amount of salicylic acid encounters the gut wall lining. The drug became popular worldwide and it was sold over the counter in the form of tablets since 1915. It is a common remedy for the relief of headache, muscular pain, rheumatic states, gout, and toothache [1].

Chemical name: Acetylsalicylic acid

Common names: ASPRO, DISPRIN, CARDIPRIN

To prepare aspirin, salicylic acid is reacted with an excess of acetic anhydride. A small amount of a strong acid is used as a catalyst which speeds up the reaction (Figure 1). The product will appear as a solid mass when crystallization is complete, and crystals are collected through vacuum filtration.

Investigations were continued to understand the basic mechanism of Aspirin’s action while clinical trials and other studies in 1960s established that it reduces the risk of heart attack. In 1971, John R. Vane from the Wellcome Research Laboratories, UK discovered the mechanism by which Aspirin exerts its antiinflammatory, analgesic and antipyretic effects [2]. He proved that Aspirin and other non-steroid anti-inflammatory drugs (NSAIDs) inhibit the activity of the enzyme now called cyclooxygenase (COX) which leads to the production of Prostaglandins (PGs), responsible for sensations of pain and processes of fever and inflammation. Aspirin acts by acetylating the hydroxyl of a serine residue in the active site of the COX enzyme. This makes Aspirin different from other NSAIDs (such as Diclofenac and Ibuprofen), which are reversible inhibitors. Moreover, Cyclooxygenase is required for synthesis of Thromboxane, responsible for the aggregation of platelets that form blood clots. So, Aspirin can also function as an efficient anti-clotting agent by irreversibly blocking the formation of Thromboxane in platelets. This entire process is depicted in Figure 2. For discoveries concerning Prostaglandin, the Nobel Prize in medicine in 1982 was awarded jointly to Sune K. Bergström, Bengt I. Samuelsson and John R. Vane.

    Paracetamol

Paracetamol is a common household drug for pain reliever and fever reducer [3]. This aniline derivative is popularly known as Paracetamol (from para-acetyl-amino-phenol) in Europe and most of the rest of the world and as Acetaminophen (from N-acetylpara- aminophenol) in the United States and Japan. The compound was first prepared in 1877 by Harmon Northrop Morse at Johns Hopkins University, but clinically tested on humans by von Mering during 1887. From a historical perspective, Acetaminophen/ Paracetamol and the related drugs such as Acetanilide (Antifebrin: 1886), Phenacetin (1887) were introduced into the market about the same time as Aspirin and the other salicylates. The sale of Aspirin was overshadowed by Phenacetin which established Bayer as a leading pharmaceutical company that time. About half a century later, it was rediscovered that Paracetamol is the active metabolite of both Phenacetin and Acetanilide [4]. After this breakthrough, Paracetamol was successfully marketed in 1953 by Sterling-Winthrop Co. as Panadol. This medicine still continues to be the most widely used analgesic antipyretics with few sideeffects and little interaction with other pharmaceutical agents.

The drug inhibits COX activities in the central nervous system, but it lacks an anti-inflammatory effect because it cannot inhibit COX in the peripheral tissues. So, unlike Aspirin and salicylates, it does not cause gastrointestinal problems or prolonged bleeding time. This family of drug is on the World Health Organization’s List of Essential Medicines, the safest and most effective medicines needed in a health system. Doses of Paracetamol greater than the recommended ones can cause severe liver damage [5].

Common names: ANACIN-3, CALPOL, CROCINE, PANADOL, TYLENOL

For production of Paracetamol, phenol is used as the starting material which is reacted with sodium nitrate giving a mixture of two isomers of which the desired nitration product, 4-nitrophenol (BP: 279°C) can easily be separated by steam distillation. The nitro group is then reduced to amine, giving 4-aminophenol. Industrially direct hydrogenation is used, but in the laboratory scale sodium borohydride serves. Finally, the amine is acetylated with acetic anhydride. The synthesis reaction is shown in Figure 3.

    Ibuprofen

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) belonging to the family of synthetic 2-arylpropionic acids (Profens) that is used for treating pain, fever and inflammation. It is mainly effective for the pain and swelling associated with arthritis. It is a reversible, non-selective COX inhibitor, lowering the level of Prostaglandins via blocking the metabolism of Arachidonic acid in the body. Ibuprofen is administered as a racemic mixture. The human body can convert the inactive (R) form into the active (S) form, so eventually 100% of the Ibuprofen taken becomes active.

Chemical name: [(±)-2-(4-isobutylphenyl)] propionic acid

Common names : BRUFEN, FENLONG, NOVAPRIN, EMFLAM. ADVIL, MOTRIN

The two most popular ways to obtain ibuprofen are the Boot process and the Hoechst process. The Boot process is an older commercial process developed by the Boot Pure Drug Company and patented in 1960s [6]. This synthesis consists of six steps and resulted in unwanted by products as shown in Figure 4. The Boots- Hoechst-Celanese (BHC) synthesis serves as a model that has genuinely contributed to green chemistry [7]. In 1992, the BHC Company developed a new, sustainable synthesis that reduced the number of synthetic steps to half (total three steps) of that in the original Boots Company method (Figure 4). It is noteworthy that the synthesis began with the same first step, e.g. acylation of isobutylbenzene, but utilized anhydrous hydrogen fluoride as both a catalyst and solvent. The reduced amount of unwanted waste due to the generation of only one molecule of water as the byproduct is another achievement of the BHC method. Ibuprofen is the first pharmaceutical compound that was recognized by the U.S. Environmental Protection Agency Presidential Green Chemistry Challenge Awards in 1997.

    Conclusion

During the past century, Aspirin and Paracetamol have occupied a central role in the treatment of fever and pain. Nonsteroidal anti-inflammatory drugs (NSAIDs) have proved to be highly efficient for getting instant relief from pain and inflammation and Ibuprofen remains the first choice for this. With evolving research on biological activity, traditional role of Aspirin has been re-defined leading to the appropriate use of this agent in clinical practice. The green synthesis of Ibuprofen has emerged resulting improved and economical yield. We can conclude that the field of medicinal chemistry based on the studies on cellular biology and pharmacology has covered a long journey to understand the mode of operation and metabolism of these synthetic drugs in the body.

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