Data produced from #cellculture systems are more physiologically relevant when human #primarycells are used, and their significance in the #research of biological processes, the progression of disease, and the development of new drugs is rising.
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Abstract
Since the nanoscale in combination with luminescent properties and prospective applications in different fields of optoelectronics and biomedicine is stimulating a growing interest towards research in the area of cadmium telluride (CdTe) quantum dots (QDs), the method of “green” synthesis of CdTe QDs with the use of the Pleurotus ostreatus mycelium culture as a biological matrix has been developed. The study of their physical and chemical characteristics has shown that the synthesized CdTe QDs are characterized by a crystalline structure and a predominantly spherical morphology and are 3–8 nm in size with the luminescence maximum within the 340–370 nm range. The study of their effects on different types of mammalian cells has shown that CdTe QDs have dose-dependent effects on mouse endothelial cells and human and rat erythrocytes, T- and B-lymphocytes, colorectal cancer cells (Colo 205), and human breast cancer cells (MCF-7). In particular, suppression of proliferative indices of endotheliocytes and an increase in the count of dead cells were observed, which indicates the cytotoxic action of nanocrystalline CdTe and its antiproliferative effect on endothelial cells. At the 5 µM concentration, CdTe QDs exhibited hemolytic activity, due to their action on erythrocytes, and affected adhesive contacts and cancer cell survivability. At the same time, human breast cancer cells (MCF-7) were more sensitive to their action. The data obtained are exclusively important for the understanding of mechanisms underlying the toxicity of CdTe QDs and for their future application in biological and biomedical research.
CELL ARISES FROM PRE-EXISTING CELL WAS STATED BY__?
Get the answer of this question in one word and much more questions and answers are available on our online ed-tech of Physics Wallah for students exam practice.
A Macrophage is in the white blood cell group and part of the immune system. * They patrol around the body, entering affected areas, engulfing and destroying bacteria and other invaders, as portrayed in this image. * They also act as a janitor, cleaning up dead cells and other debris around the body, keeping it clean. * * #macrophage #bacteria #immunesystem #whitebloodcells #singlecell #organism #prokaryotic #eukaryotes #humancells #biotechnology #biology #cellbio #staphinfection #archaea #medicalillustration #medicalanimation #scientificillustration #scientificanimation #singlecellanimation #sciart #viscom #science #scicomm #newyorkcity #newjersey (at Boston, Massachusetts) https://www.instagram.com/p/Btnxu0GhwW7/?utm_source=ig_tumblr_share&igshid=kh1jxf7hmttz
WHO Honors Henrietta Lacks as Family Pursues Justice Henrietta Lacks, the Black lady whose c... Read the rest on our site with the url below https://worldwidetweets.com/who-honors-henrietta-lacks-as-family-pursues-justice/?feed_id=91315&_unique_id=6168f4396bc3c #HenriettaLacks #humancells #justice #lawsuit #polio #research #stemcells
The most detailed representation of a human cell to date, obtained by radiography, nuclear magnetic resonance and cryoelectronic microscopy. ##scienceisreal #scienceiscool #humancells #cellsatwork #cellshot #microscopy #microscopyart #coolstuff #naturebrilliance #natureperfection (at Catalina Foothills, Arizona) https://www.instagram.com/p/CNtKcEmrijac616I9LHAw5NJkm9pZtODzOIgK00/?igshid=1dojajqyombz3