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International consortium with NASA reveals hidden impact of spaceflight on gut health
Scientists have uncovered how spaceflight profoundly alters the gut microbiome, revealing previously unknown effects on host physiology that could shape the future of long-duration space missions.
Led by University College Dublin (UCD) and McGill University, Canada, in collaboration with NASA and an international consortium, the research offers the most detailed profile to date of how space travel impacts the gut microbes we carry into space.
Published in npj Biofilms and Microbiomes, the study used advanced genetic technologies to examine changes in the gut microbiome, colons, and livers of mice aboard the International Space Station (ISS) over three months. The findings reveal significant shifts in specific bacteria and corresponding changes in host gene expression associated to immune and metabolic dysfunction commonly observed in space, offering new insights into how these changes may affect astronaut physiology during extended missions.
Dr Emmanuel Gonzalez, McGill University, and first author of the study, said: "Spaceflight extensively alters astronaut physiology, yet many underlying factors remain a mystery. By integrating new genomic methods, we can simultaneously explore gut bacteria and host genetics in extraordinary detail and are beginning to see patterns that could explain spaceflight pathology. It’s clear we’re not just sending humans and animals to space, but entire ecosystems, the understanding of which is crucial to help us develop safeguards for future space exploration." 
The international collaboration, spearheaded by UCD with NASA GeneLab’s Analysis Working Groups, is part of the recent Nature Portfolio package: The Second Space Age: Omics, Platforms and Medicine across Space Orbits - the largest coordinated release of space biology discoveries in history. These findings highlight Ireland's growing role in microbiome and space life sciences research and demonstrate how understanding biological adaptations to spaceflight can not only advance aerospace medicine but also have significant implications for health on Earth.
Professor Nicholas Brereton, UCD School of Biology and Environmental Science, and senior author of the study, said: "These discoveries highlight the intricate dialogue between specific gut bacteria and their mouse hosts, critically involved in bile acid, cholesterol, and energy metabolism. They shed new light on the importance of microbiome symbiosis to health and how these Earth-evolved relationships may be vulnerable to the stresses of space. We hope this research exemplifies how cooperative Open Science can drive discoveries with clear medical benefits on Earth, while also supporting the upcoming Artemis missions, the deployment of the Gateway deep space station, and a crewed mission to Mars."
Ames Space Biology Portfolio Scientist, NASA Ames Research Center, Jonathan Galazka said: "These discoveries are an important piece in our understanding of how spaceflight impacts astronauts and will aid the design of safe and effective missions to Earth orbit, the Moon, and Mars. Moreover, the collaborative nature of this project is a blueprint for how Open Science can accelerate the pace of discovery.”
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diaryoftheloser · 1 day
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Aver - The Loser, The Commonplacer
I look forward to recieving your support...
Just to clarify, I am fairly new to this, hence for clarity I am gonna use two blogs
@diaryoftheloser - To keep track of my daily activities
@thecommonplacer - For brainstorming, organising content
💬 Who Am I?
Name/Pronouns: Aver (She/Her) From: Dubai, United Arab Emirates 🇦🇪 Identity: Queer and thriving in STEM Currently: Freelancer - Incoming Biotechnology Master's Student Field of Study/Work: Omics Data Science, Scientific Communication Reason for Starting the Blog: My First Post Fun Fact: I am also Digital Illustrator (Minor in Animation) Biggest Science Nerd Moment: Volunteering and presenting at my very first International Conference 🌍
🔬 Research Interests
Nucleic Acid Sciences 🧬 Omics Technology 📊 Data Science & Engineering 💻 Statistics 📈 Immunology 🦠 Business in Biotechnology & Life Sciences 🧪
🎧 When I’m Not Doing Science
Music: English Pop, Korean & Thai OSTs (I want to expand my playlist) Shows/Movies: RomComs, Asian - Thai, Korean, Japanese, Chinese, Taiwanese, Indian (sometimes Filipino and Vietnamese) Books: Productivity, Psychology, Manga, Manhwa Hobbies: Typography
✨ Goals
✈️ Short Term Goals: Lose 10kgs, Earn a Driver's License, Strengthen Computational Expertise, Prepare for Biotech National Exams, Learn to Cook, Move to Singapore 🌈 Long Term Goals: Pre-Ph.D. Preparation, Financial Independence, Financially Support My Family, Upgrade My Wardrobe and Aesthetics, Fulfill Travel Wishlist 🦄 Career Goals: Turning My Future Ph.D. Work into a Unicorn, Fixed Additional Sources of Income 💼 Productivity Goals: Being Consistent with Notion Productivity
Goals for 100 Days of Productivity (100 Days to The Year 2025):
Lose 10 Kgs
Earn a Driver's License
Finish Pending Projects - Research Paper, Conference Presentation
Biotech National Exam Preparation
Finish Three Career Tracks on Data Camp
Submission for The Food Innovation Challenge
Goals for 300 Days of Productivity:
The Mega Pre-Ph.D. Prep
Recycle all used papers and donate books
Move to Singapore
Financial Education
Complete Udemy Courses and left over Data Camp Career Tracks
🔗Links to My Resources:
My Current Self-Care Routine
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colinwilson11 · 14 days
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Smart Drug Design Through Fragment-Based Approaches Will Drive Growth In The Global Fragment Based Drug Discovery Market
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The fragment based drug discovery approach involves screening libraries of very small molecules called fragments that bind to targets of therapeutic interest with low molecular weight and high binding efficiency. These fragments act as starting points for developing potential drug candidates. Compared to high-throughput screening, fragment-based methods require smaller libraries that can be easily synthesized and screened. Fragment hits have low affinity but high efficiency that improves the probability of growing them into potent and selectiveligands through structure based drug design.
The Global Fragment Based Drug Discovery Market is estimated to be valued at US$ 0.795 Bn in 2024 and is expected to exhibit a CAGR of 15% over the forecast period 2024-2031.
Key players operating in the fragment based drug discovery market include Astex Pharmaceuticals, Beactica AB, Charles River Laboratories International, Inc., Evotec AG, and Alveus Pharmaceuticals Pvt. Ltd.
Key Takeaways
Key players operating in the fragment based drug discovery market are focusing on expanding their fragment libraries and enhancing screening capabilities to identify novel hits. For instance, in 2022, Astex Pharmaceuticals significantly expanded its fragment library collection to over 450,000 fragments to enable robust hit identification.
The growing incidence of chronic diseases coupled with rising drug discovery and development activities is fueling the demand for fragment-based techniques. Fragment based screening allows developing biologically relevant leads with superior physiochemical and pharmacological properties compared to high-throughput screening.
Technological advancements in biophysical methods such as NMR, crystallography, mass spectrometry and computational modeling tools have widened the application scope of fragment based approaches in hit identification and optimization stages of drug R&D. In 2023, Evotec AG introduced the PanOmics platform to integrate omics data for enhancing fragment hits using systems chemical biology approaches.
Market Trends
De-risking drug candidates: Fragment based screening enables identifying low risk hits bound to attractive regions of target proteins with high efficiency. By optimizing these fragments, drug candidates with lower biological and chemical liability can be developed.
Integrating biophysical methods: Combining multiple biophysical techniques such as X-ray crystallography, NMR spectroscopy, SPR, and SBM provides comprehensive structural and binding information for fragment evolutions and optimization.
Leveraging artificial intelligence: Machine learning and deep learning based computational tools are being increasingly used to process, analyze and interpret large experimental datasets generated through fragment screening campaigns to facilitate hit discovery and design.
Market Opportunities
Growing collaboration between pharmaceutical companies and academic research institutes is expected to boost knowledge sharing and resource optimization for fragment libraries creation and screening. Moreover, increasing R&D investments and funding support from governments and private organizations will facilitate clinical research on fragment-derived drug candidates.
Impact Of COVID-19 On Global Fragment Based Drug Discovery Market:
The COVID-19 pandemic has significantly impacted the Global Fragment Based Drug Discovery Market. During the initial lockdown phase, drug discovery activities were disrupted as research labs and facilities were shut down to curb the virus spread. This led to delays in lab experiments, screening programs and drug development timelines. Researchers faced difficulties in accessing facilities for fragment screening, biophysical analyses and hit validation studies. Supply chain disruptions also created shortages of laboratory consumables and reagents required for fragment based screening assays.
However, as restrictions eased in late 2020, companies resumed operations with new safety protocols. Many shifted their focus towards developing treatments and vaccines for COVID-19. Fragments screening emerged as a promising approach for rapidly identifying potent antiviral hits against the SARS-CoV-2 virus. Several academic and pharmaceutical institutions employed their expertise and infrastructure in fragment based drug design to speed up the search for COVID-19 therapies. Government and private funding also increased for coronavirus drug development projects utilizing fragment screening techniques.
Going forward, companies are expected to leverage learnings from the pandemic. More efficient hybrid models blending onsite and remote working may be adopted. Fragment screening capabilities will be expanded to enable rapid response against future health emergencies. Enhanced collaborations between industry and academia can help expedite drug discovery programs. Overall, with resurgence plans and improved resilience, the long-term impact of COVID-19 on the fragmented based drug discovery market is expected to be positive.
Geographical Regions Of Concentrated Market Value:
The global fragmented based drug discovery market in terms of value is highly concentrated in North American and European countries. The United States holds the largest market share currently due to strong presence of leading pharmaceutical and biotechnology companies. Many top players have their core research and development centres located in the US and are involved in internal and collaborative fragment screening programs. Europe is also a major revenue generator owing to substantial investments in drug discovery research by both private sector and government research councils in countries like Germany, United Kingdom and France.
Fastest Growing Region:
The Asia Pacific region is anticipated to experience the highest growth in the global fragmented based drug discovery market over the forecast period. Factors such as increasing government focus on enhancing domestic innovation, rising biopharmaceutical industry investments, and growing skilled workforce availability are fueling market expansion in Asia Pacific. Countries like China, India and South Korea are emerging hubs for low-cost high quality contract research and manufacturing. This is attracting several multinational companies to establish fragment screening centers and collaborations in Asia to tap growth opportunities. Additionally, improving Intellectual Property (IP) frameworks and favorable business policies will further support market penetration of fragmented based drug discovery technologies across Asia Pacific.
Get more insights on this topic:https://www.trendingwebwire.com/global-fragment-based-drug-discovery-market-is-estimated-to-witness-high-growth-owing-to-technological-advancement-in-fragment-based-screening-techniques/
About Author:
Priya Pandey is a dynamic and passionate editor with over three years of expertise in content editing and proofreading. Holding a bachelor's degree in biotechnology, Priya has a knack for making the content engaging. Her diverse portfolio includes editing documents across different industries, including food and beverages, information and technology, healthcare, chemical and materials, etc. Priya's meticulous attention to detail and commitment to excellence make her an invaluable asset in the world of content creation and refinement. (LinkedIn - https://www.linkedin.com/in/priya-pandey-8417a8173/)
What Are The Key Data Covered In This Global Fragment Based Drug Discovery Market Report?
:- Market CAGR throughout the predicted period
:- Comprehensive information on the aspects that will drive the Global Fragment Based Drug Discovery Market's growth between 2024 and 2031.
:- Accurate calculation of the size of the Global Fragment Based Drug Discovery Market and its contribution to the market, with emphasis on the parent market
:- Realistic forecasts of future trends and changes in consumer behaviour
:- Global Fragment Based Drug Discovery Market Industry Growth in North America, APAC, Europe, South America, the Middle East, and Africa
:- A complete examination of the market's competitive landscape, as well as extensive information on vendors
:- Detailed examination of the factors that will impede the expansion of Global Fragment Based Drug Discovery Market vendors
FAQ’s
Q.1 What are the main factors influencing the Global Fragment Based Drug Discovery Market?
Q.2 Which companies are the major sources in this industry?
Q.3 What are the market’s opportunities, risks, and general structure?
Q.4 Which of the top Global Fragment Based Drug Discovery Market companies compare in terms of sales, revenue, and prices?
Q.5 Which businesses serve as the Global Fragment Based Drug Discovery Market’s distributors, traders, and dealers?
Q.6 How are market types and applications and deals, revenue, and value explored?
Q.7 What does a business area’s assessment of agreements, income, and value implicate?
*Note: 1. Source: Coherent Market Insights, Public sources, Desk research 2. We have leveraged AI tools to mine information and compile it
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The Space Omics and Medical Atlas (SOMA) and international astronaut biobank | Nature
Here we present the Space Omics and Medical Atlas (SOMA), an integrated data and sample repository for clinical, cellular and multi-omic research profiles from a diverse range of missions, including the NASA Twins Study7, JAXA CFE study8,9, SpaceX Inspiration4 crew10,11,12, Axiom and Polaris. The SOMA resource represents a more than tenfold increase in publicly available human space omics data, with matched samples available from the Cornell Aerospace Medicine Biobank. The Atlas includes extensive molecular and physiological profiles encompassing genomics, epigenomics, transcriptomics, proteomics, metabolomics and microbiome datasets, which reveal some consistent features across missions, including cytokine shifts, telomere elongation and gene expression changes, as well as mission-specific molecular responses and links to orthologous, tissue-specific mouse datasets.
https://www.nature.com/articles/s41586-024-07648-x
Атлас SOMA (Space Omics and Medical Atlas) предлагает интегрированный репозиторий клинических, клеточных и мультиомных данных из различных миссий, включая исследование NASA Twins и SpaceX Inspiration4. Выявлены общие изменения, такие как сдвиги цитокинов и изменения экспрессии генов, а также уникальные реакции, характерные для отдельных миссий. Эти данные важны для разработки методов мониторинга здоровья и мер противодействия заболеваниям для будущих миссий на Луну, Марс и в глубокий космос.
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creativeera · 2 months
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Cancer Biomarkers Market Poised to Exhibit a CAGR of 7.3% by 2031
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Cancer biomarkers are substances whose presence is indicative of some biological condition, processes, or pathology. They can be used for cancer diagnosis or checking effectiveness of treatment. Being non-invasive procedures, demand for cancer biomarkers is growing rapidly. They aid in early detection of cancer during screening programs and reduce cost of cancer treatment. Global cancer biomarkers market is estimated to be valued at USD 25.60 Bn in 2024 and is expected to reach USD 59.01 Bn by 2031, exhibiting a compound annual growth rate (CAGR) of 12.7% from 2024 to 2031.
Key Takeaways Key players operating in the Cancer Biomarkers market are Schlumberger Limited, Rockwell Automation Inc., SIS-TECH Solutions LP, Emerson Electric Company, HIMA Paul Hildebrandt GmbH, Honeywell International Inc., Siemens AG, Yokogawa Electric Corporation, Schneider Electric SE, and ABB Ltd. They are investing heavily in biomarker detection methods and panels targeting unmet clinical needs. Rising incidence of cancer across the world is driving for Cancer Biomarkers Market Demand. Biomarkers help in cancer screening and detecting disease at early stages. This improves treatment outcomes and survival rates significantly. Initiatives by governments and cancer councils to spread cancer awareness are also boosting the market. Global expansion strategies adopted by leading players are expected to support market growth during the forecast period. They are expanding their footprint in emerging markets of Asia Pacific, Latin America, and Middle East & Africa to tap the high growth opportunities. This will increase access to advanced cancer diagnostic solutions. Market Key Trends The use of artificial intelligence and machine learning algorithms to discover novel biomarkers from large datasets is a key trend in the market. It helps accelerate the process of biomarker identification. Genomic and proteomic biomarkers are also gaining traction for their role in cancer detection as well as tracking cancer progression and drug response. Development of personalized diagnostics based on multi-omics approaches and liquid biopsy tests are some other trends expected to shape the market.
Porter’s Analysis Threat of new entrants: The cancer biomarkers market requires huge capital investments in R&D for developing novel biomarkers and testing kits which makes the entry difficult for new players. Bargaining power of buyers: Buyers have moderate bargaining power in this market as there are many players offering similar cancer biomarker testing services. Bargaining power of suppliers: Suppliers have low bargaining power due to availability of alternative raw material suppliers in the market. Threat of new substitutes: Substitutes have low threat as there are limited substitutes available for cancer biomarker tests. Competitive rivalry: The market is highly competitive due to presence of many global as well as regional players. Geographical Regions North America region accounts for the largest share of the cancer biomarkers market in terms of value due to presence of major players, rising healthcare expenditure and increasing prevalence of cancer in the region. Asia Pacific is expected to grow at the fastest CAGR during the forecast period owing to increasing awareness regarding cancer, improving healthcare infrastructure and rising access to diagnostic services in emerging economies of China and India in this region.
Get more insights on Cancer Biomarkers Market
About Author:
Money Singh is a seasoned content writer with over four years of experience in the market research sector. Her expertise spans various industries, including food and beverages, biotechnology, chemical and materials, defense and aerospace, consumer goods, etc. (https://www.linkedin.com/in/money-singh-590844163)
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nosubjekt · 2 months
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The 25th Global Nephrology, Urology and Kidney Failure Congress caught her eye, because the conference website listed several “renowned speakers”.
But on arriving at the conference venue, a four-star hotel near London’s Heathrow airport, Loren could find no conference signage. Eventually she knocked on a door with a sign reading ‘Pulsus meeting’, a name Loren didn’t recognize. Inside, a flustered young man told her that the nephrology congress was being held in conjunction with other medical events.
Inside were three rows of desks, which would be occupied by a total of 21 people over the course of the day. The first two in-person talks were about ophthalmology. Subsequent talks covered drug toxicity, dentistry and antibiotics. Loren and the other attendees became increasingly flummoxed as the day went on. One had come from Jamaica for a midwifery conference, but no midwifery talk was delivered. Others had travelled from countries including Ukraine, Iran and the United States. The conference company had also scheduled a renewable-energy conference for the same date and venue. These had all morphed into what the organizer, named Conference Series, called the 30th Global Healthcare Summit. Conference Series, like Pulsus, is part of a publisher and conference organizer named OMICS International.
https://www.nature.com/articles/d41586-024-02358-w
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leedsomics · 3 months
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Single-cell proteomics of Arabidopsis leaf mesophyll identifies drought stress-related proteins
The application of single-cell omics tools to biological systems can provide unique insights into diverse cellular populations and their heterogeneous responses to internal and external perturbations. Thus far, most single-cell studies in plant systems have been limited to RNA-sequencing approaches, which only provide indirect readouts of cellular functions. Here, we present a single-cell proteomics workflow for plant cells that integrates tape-sandwich protoplasting, piezoelectric cell sorting, nanoPOTS sample preparation, and FAIMS-based MS data acquisition method for label-free single-cell proteomics analysis of Arabidopsis leaf mesophyll cells. From a single leaf protoplast, over 3,000 proteins were quantified with high precision. The workflow is demonstrated to identify stress associated changes in protein abundance by analyzing >80 protoplasts from well-watered and water-deficit stressed plants. Additionally, we describe a new approach for constructing covarying protein networks at the single-cell level and demonstrate how single-cell protein covariation analysis can reveal previously unrecognized protein functions while also capturing stress-induced changes in protein-protein dynamics. http://dlvr.it/T98xQl
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jayanthitbrc · 3 months
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Unveiling Growth Trends and Market Size in the ADME Toxicology Testing Market
Overview and Scope ADME toxicology testing is a set of studies conducted to assess the potential toxicity of a substance or drug candidate based on its absorption, distribution, metabolism, and excretion (ADME) properties. These tests are used in drug development to ensure the well-being of individuals exposed to substances. Sizing and Forecast The adme toxicology testing market size has grown rapidly in recent years. It will grow from $9.3 billion in 2023 to $10.34 billion in 2024 at a compound annual growth rate (CAGR) of 11.2%.  The  growth in the historic period can be attributed to stringent regulatory requirements, rising drug development activities, growing concerns about drug safety, advancements in in vitro testing methods, increased outsourcing of toxicology studies.. The adme toxicology testing market size is expected to see rapid growth in the next few years. It will grow to $15.77 billion in 2028 at a compound annual growth rate (CAGR) of 11.1%.  The growth in the forecast period can be attributed to rapid expansion of biopharmaceuticals, growing emphasis on personalized medicine, emergence of advanced therapies, enhanced predictive toxicology models, global increase in chemical safety testing. To access more details regarding this report, visit the link: https://www.thebusinessresearchcompany.com/report/adme-toxicology-testing-global-market-report Segmentation & Regional Insights The adme toxicology testing market covered in this report is segmented – 1) By Product Type: Instruments, Software Solutions, Assays Systems, Reagents, Other Products 2) By Method: Cellular Assay, Biochemical Assay, In Silica, Ex-vivo 3) By Technology: Cell Culture, High Throughput, Molecular Imaging, OMICS Technology, Other Technologies 4) By Application: Systemic Toxicity, Renal Toxicity, Hepatotoxicity, Neurotoxicity, Other Applications 5) By End-User: Cosmetics And Household Products, Pharmaceutical Industry, Animal Industry, Food Industry, Other End Users North America  was the largest region in the ADME toxicology testing market in 2023. Asia-Pacific  is expected to be the fastest-growing region in the forecast period. The regions covered in the adme toxicology testing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East,  Africa. Intrigued to explore the contents? Secure your hands-on sample copy of the report: https://www.thebusinessresearchcompany.com/sample.aspx?id=11922&type=smp Major Driver Impacting Market Growth The rising demand for novel drugs is expected to propel the growth of the ADME toxicology testing market going forward. Novel drugs are pharmaceutical substances that have not been previously approved or marketed for therapeutic use. ADME toxicity testing is a major step in drug development to ensure that the novel drug is safe and doesn’t produce any harmful toxins in the body. Key Industry Players Major companies operating in the adme toxicology testing market report are AbbVie Inc., Thermo Fisher Scientific Inc., Boehringer Ingelheim GmbH, Laboratory Corporation of America Holdings, Corning Incorporated, Eurofins Scientific SE, Agilent Technologies Inc., Lonza Group AG, Dassault Systèmes SE, Catalent Inc., Charles River Laboratories International Inc., Beckman Coulter Inc., PerkinElmer Inc., Bio-Rad Laboratories Inc. The adme toxicology testing market report table of contents includes: 1. Executive Summary
2. Market Characteristics
3. Market Trends And Strategies
4. Impact Of COVID-19
5. Market Size And Growth
6. Segmentation
7. Regional And Country Analysis .
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27. Competitive Landscape And Company Profiles
28. Key Mergers And Acquisitions
29. Future Outlook and Potential Analysis Contact Us: The Business Research Company Europe: +44 207 1930 708 Asia: +91 88972 63534 Americas: +1 315 623 0293 Email: [email protected] Follow Us On: LinkedIn: https://in.linkedin.com/company/the-business-research-company   Twitter: https://twitter.com/tbrc_info   Facebook: https://www.facebook.com/TheBusinessResearchCompany   YouTube: https://www.youtube.com/channel/UC24_fI0rV8cR5DxlCpgmyFQ   Blog: https://blog.tbrc.info/   Healthcare Blog: https://healthcareresearchreports.com/   Global Market Model: https://www.thebusinessresearchcompany.com/global-market-model  
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wellnessweb · 3 months
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AI Revolutionizes Cancer Diagnosis: Unveiling a Growing Market Size
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The AI in Cancer Diagnosis Market was valued at USD 195 Million in 2023 and is expected to reach at USD 1238.79 Million by 2031 and grow at a CAGR of 26% over the forecast period of 2024-2031.AI's impact on the cancer diagnosis market has been trans formative, ushering in a new era of precision and efficiency. By harnessing vast amounts of data and employing advanced algorithms, AI systems can detect subtle patterns and anomalies in medical images and patient records that might elude human eyes. This capability not only accelerates the diagnostic process but also enhances accuracy, thereby improving patient outcomes. Moreover, AI-driven tools enable oncologists to tailor treatments more precisely to individual patients, considering factors like genetic profiles and treatment response predictions. As AI continues to evolve, its role in cancer diagnosis promises to further revolutionize healthcare, offering hope for earlier detection, more effective therapies, and ultimately, better survival rates for cancer patients worldwide.
Get Sample of This Report @ https://www.snsinsider.com/sample-request/2772
Market Scope & Overview
Readers will find information in the most recent research on current trends, chances, and elements that could have an impact on future growth, as well as a basic review of the international Cancer Biomarkers Market. A high-level overview of the market and its lucrative potential is provided in this report. The analysis looks into market drivers, difficulties, and opportunities in addition to market size. The report also shows the market shares of the top companies and the state of competition among the main competitors in the industry.
The latest market research conducts a detailed investigation of the Cancer Biomarkers Market. The market estimations and forecasts in the research report are based on primary interviews, extensive secondary research, and the insights of internal subject matter experts. The examination of a number of important factors, such as product performance, market share expansion, and investments in emerging markets, to name a few, is made possible with the help of market research.
Market Segmentation Analysis
By Biomarkers Type
Protein Biomarkers
Genetic Biomarkers
Other Cancer Biomarkers
By Cancer Type
Breast Cancer
Lung Cancer
Colorectal Cancer
Prostate Cancer
Melanoma
Leukemia
Thyroid Cancer
Bladder Cancer
Non-Hodgkin's Lymphoma
Kidney Cancer
Other Cancer Types
By Profiling Technologies
Omics Technologies
Imaging Technologies
Immunoassay
Bioinformatics
Cytogenetics
By Application
Diagnostics
Research & Development
Prognostics
Risk Assessment
Other Profiling Technologiess
COVID-19 Impact Analysis
The impact of supply and demand on the target market is examined in the research. In addition to private databases and a paid data source, this study report used both primary and secondary sources of information. The impact of COVID-19 on the domestic and international Cancer Biomarkers Marketplaces is covered in this study. The market players will design pandemic preparedness measures with the help of the COVID-19 impact study.
Regional Outlook
The effects of COVID-19 on a variety of geographic markets, including North America, Latin America, Asia Pacific, Europe, and the Middle East and Africa, are thoroughly examined in the Cancer Biomarkers Market research investigation.
Competitive Analysis
This Cancer Biomarkers Market research analysis comprehensively examines the effects of COVID-19 on numerous geographical markets, including North America, Latin America, Asia Pacific, Europe, and the Middle East and Africa.
Key Reasons to Purchase Cancer Biomarkers Market Report
The market research examines the structure of the global market, market segmentation, growth rates, and comparisons of revenue share.
Market forecasts and estimates consider the many political, social, and economic variables that will affect market expansion as well as the current state of the business.
Conclusion
The research report analyses the global market and conducts research on consumption, value, year-over-year growth, and future development plans in order to provide a complete picture of the Cancer Biomarkers Market.
Read Full Report @ https://www.snsinsider.com/reports/ai-in-cancer-diagnosis-market-2772
About Us
SNS Insider is a market research and insights firm that has won several awards and earned a solid reputation for service and strategy. We are a strategic partner who can assist you in reframing issues and generating answers to the trickiest business difficulties. For greater consumer insight and client experiences, we leverage the power of experience and people.
When you employ our services, you will collaborate with qualified and experienced staff. We believe it is crucial to collaborate with our clients to ensure that each project is customized to meet their demands. Nobody knows your customers or community better than you do. Therefore, our team needs to ask the correct questions that appeal to your audience in order to collect the best information.
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almadengenomics · 4 months
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BIO International Convention
Almaden team will be attending this year's BIO International Convention and sharing insights about g.nome®, our end-to-end hashtag#omics data science solution that enables scientists to select the right datasets, run pre-built workflows, dig deeper with tertiary analysis, and modify as needed along the way with complete traceability and reproducibility of results.
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New Drug Development and Clinical Trial Design by Applying Genomic Information Management
1. Background: Effective Clinical Trials Using Genomic Information
The human genome includes variants of DNA base sequences and epigenetic mutations, including changes in DNA methylation and histone acetylation patterns. Genomic variations, which include mutations in drug metabolism-related genes, can affect the pharmacokinetics, pharmacodynamics, efficacy, and safety of drugs [1,2]. This review describes the use of drug-related genomic information in drug development and clinical trial design. Personalized next-generation clinical trials, based on the individual genome, can be designed to maximize drug efficacy and minimize side effects.
With the rapid development of genome analysis technologies and computer performance, vast amounts of genomic information have been generated, which can be utilized in precision medicine. Representative cancer-related genomic information includes epidermal growth factor receptor (EGFR) mutation in non-small cell lung cancer (NSCLC) [3,4], ABL1 gene recombination in chronic myelogenous leukemia (CML) [5], and BRAF mutations in melanoma [6,7,8]. Genomic information related to cancer induction is available in databases, such as The Cancer Genome Atlas (TCGA) [9], Internal Cancer Genome Consortium (ICGC) [10], COSMIC [11], cBioPortal [12], OncoKB [13], MutaGene [14], and Cancer Genome Interpreter [15].
Open cancer genome data are generated using high-throughput technology. Cancer genome data published in TCGA include omics and clinical data of genomic variants, RNA-seq, and DNA methylation [9]. In cBioPortal, which is a rapid user-friendly platform, data on survival analysis related to variants, histological type, RNA-seq, or comparative analysis with methylation information are available [12]. The number of breast cancer patients is the largest in TCGA, in which variant information on 986 patients in 1097 clinical cases was reported. However, clinical data from TCGA do not include information about the drugs administered to the patients. There is no information on the effects and side effects of the prescribed drugs for each type of cancer. The effects of drugs can be estimated based on genomic information (mainly genomic variants) in individual clinical trials in “Drug Resistance” database [16] in COSMIC and CancerDR [17], and clinical trial results can be obtained from clinicaltrials.gov (accessed on 21 July 2022) [18].
Click here discover more about new drug development and clincial trail :
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How Endurance Exercise Training Affects Biological Molecules: New Research.
As part of an ongoing national research effort to better understand how physical activity improves health and prevents disease, seven University of Colorado Department of Medicine faculty members contributed to an article recently published in Nature, an international journal of science.  The paper, “Temporal dynamics of the multi-omic response to endurance exercise training,” discusses how…
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evoldir · 5 months
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Fwd: Conference: KsiazCastle_Poland.Genetics.Sep10-13
Begin forwarded message: > From: [email protected] > Subject: Conference: KsiazCastle_Poland.Genetics.Sep10-13 > Date: 16 April 2024 at 05:12:52 BST > To: [email protected] > > > > > Hello, > on behalf of the organizational and scientific committees I would like > to ask you to send an invitation to participants or post information > about the international conference organized by our Department on the > website. Below I am sending information about the conference and a > link to the website. We have invited speakers with very interesting > presentation topics. > > On behalf of the organizing and scientific committee of the conference, > we cordially invite you to participate in the jubilee international > conference XXXth Genetic Days. The conference will be held on September > 10-13, 2024, at Książ Castle in Poland. > > The conference covers a wide range of topics related to animal and plant > genetics, including the analysis of polymorphisms and various omics, the > use of artificial intelligence in genetic analysis, and the application > of genetics in forensics. > > Further details can be found on the conference website > www.30thgeneticdays.pl > > Additionally, a show of Silesian horses is planned as part of the > conference. The only stud of these horses is located in the Książ > Stallion Herd in historic stable buildings.  We look forward to meeting > you in September at the beautiful Książ Castle. > > Thank you very much and best regards > Magdalena Zatoń-Dobrowolska > > Dr hab. inż. Magdalena Zatoń-Dobrowolska, profesor uczelni > Uniwersytet Przyrodniczy we Wrocławiu > Katedra Genetyki > > Dr Magdalena Zatoń-Dobrowolska > > Associate professor > > Wroclaw University of Environmental and Life Sciences > Department of Genetics > > ul. Kożuchowska 7 > 51-631 Wrocław > Poland > tel. +48 71 3205920 > e-mail: > [email protected] > > ORCID0000-0002-3096-4113 > > Administratorem > Państwa danych osobowych w związku z prowadzoną korespondencją > jest Uniwersytet Przyrodniczy we Wrocławiu, ul. C. K. Norwida 25, > 50-375 Wrocław. Administrator powołał Inspektora Ochrony Danych, > z którym można skontaktować się za pośrednictwem wiadomości e-mail > ([email protected]). > > Państwa dane osobowe przetwarzane będą w celu prowadzenia > niniejszej korespondencji, udzielenia informacji i przez czas jej > trwania. Przysługuje Państwu prawo dostępu do danych, ich sprostowania, > ograniczenia przetwarzania, usunięcia, żądania sprzeciwu wobec > przetwarzania oraz wniesienia skargi do Prezesa Urzędu Ochrony Danych > Osobowych. Szczegółowe informacje na temat ochrony danych osobowych > dostępne są wPolityce Prywatności. > > Magdalena Zatoń-Dobrowolska
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Understanding Halal Certification in Philippines: Procedures and Importance
Introduction:
Halal Certification in Philippines, in which cultural variety is broadly identified, Halal certification is vital, in particular within the food and fitness industries. Halal, an Arabic period that means "permissible" or "lawful" with Islamic regulation, extends beyond dietary recommendations to encompass several products and services. This textual content delves into the specifics of Halal Certification in Philippines, exploring the techniques involved and emphasizing its significance in a country regarded for its rich cultural tapestry.
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What is Halal Certification in Philippines?
Halal Certification in Philippines is the proper technique. It is completed with the benefit of certifying our bodies to ensure that products and services observe Islamic dietary criminal guidelines and mind. It isn't restricted to virtual food; as a substitute, it includes a large spectrum, with cosmetics, pharmaceuticals, and health properly offered. The purpose is to guarantee Muslim customers that their goods and services interact with their spiritual beliefs.
Procedures for Obtaining Halal Certification in Philippines:
Application Process:
The journey in the direction of Halal Certification in the Philippines began with applying to a diagnosed certifying body. The National Commission normally authorizes these bodies on Muslim Filipinos (NCMF), the authority enterprise overseeing topics related to Muslim affairs.
Documentation:
Detailed documentation is wanted to confirm the halal recognition of the products or offerings. This can also embody unique lists, manufacturing techniques, and special applicable data. Clear and correct documentation is essential for the certification gadget.
Halal Assurance System:
Establishing a strong Halal Certification in Philippines Assurance System is a key element. This consists of enforcing practices and strategies to ensure that every diploma of production, from sourcing raw materials to the closing product, adheres to halal requirements.
On-Site Inspection:
Certifying our frame's behavior on the internet website online online inspections to affirm the information furnished within the documentation. This step is essential for assessing the real implementation of halal practices inside the manufacturing or corporation facilities.
Halal Committee Review:
A Halal Committee of experts in Islamic regulation and relevant industries evaluations the documentation and inspection critiques. They ensure everybody's requirement is met before awarding the Halal Certification in the Philippines.
Certification Issuance:
Once the Halal Committee is happy, the certifying body troubles the Halal Certification. This certification is a testament that the goods or offerings comply completely with Islamic nutritional crook guidelines and are appropriate for consumption as a beneficial resource for Muslims.
Importance of Halal Certification in Philippines:
Catering to Muslim Consumers:
With a huge Muslim population in Philippines, obtaining Halal Certification is a strategic business corporation employer drift. It permits organizations to faucet proper right into a broader market and produces collectively accepted as true with Muslim clients who prioritize halal merchandise.
Global Market Access:
Halal Certification in Philippines opens doorways to global markets, particularly in areas with large Muslim populations. Products and offerings with Halal Certification are more likely to be famous in international markets, improving export opportunities for Filipino companies.
Boosting Tourism:
The Philippines is a famous vacation destination, attracting visitors from numerous backgrounds to net web page sites. Having Halal Certification in the hospitality and food industries ensures that Muslim vacationers are welcome and can, therefore, find halal options at some point during their stay.
Promoting Economic Growth:
The authorities assist in the omic boom by encouraging agencies to take advantage of Halal Certification in the Philippines. It fosters the improvement of halal-compliant industries, develops employment opportunities, and contributes to our general monetary prosperity.
Respecting Cultural Sensitivities:
Halal Certification in the Philippines displays a strength of mind to understand the cultural and non secular sensitivities of the numerous populace within the Philippines. It promotes an inclusive and tolerant society where humans of multiple faiths coexist harmoniously.
Ensuring Product Integrity:
Halal Certification could be a better label; it represents an energy of will to integrity in production. It assures clients that the goods they purchase aren't halal but meet the slight necessities of pinnacle-notch hygiene.
Why Should Factocert Choose for Halal Certification in the Philippines?
"Choosing Factocert for Halal Certification in the Philippines is a strategic preference that guarantees seamless adherence to Halal necessities. With data spanning Manila, Quezon City, Cebu, and Davao, Factocert guarantees meticulous certification techniques tailor-made to community regulatory nuances. Their willpower for excellence and in-intensity records in the Philippine markets make them the famous choice. Factocert successfully navigates Halal Certification's complexities in the Philippines, ensuring corporations in key towns meet stringent requirements. Opting for Factocert now not sincerely secures Halal compliance but unlocks marketplace functionality in Manila, Quezon City, Cebu City, and Davao City."
Conclusion:
In the give up, Halal Certification in the Philippines is a multifaceted way that goes past making sure meals' permissibility. It consists of big industries, promoting monetary increase, cultural respect, and international market right of entry. As businesses within the Philippines apprehend the importance of catering to the numerous dreams of their population, obtaining Halal Certification emerges as a pivotal step in inclusivity and prosperity. By adhering to halal ideas, we no longer only meet our Muslim customers' dreams but define ourselves worldwide as a vacation spot for halal-compliant services and products.
For More Information, Visit Halal Certification in the Philippines
Related links:
ISO 13485 Certification in Philippines
ISO 14001 Certification in Philippines
ISO 45001 Certification in Philippines
ISO 27001 Certification in Philippines
ISO 22000 Certification in Philippines
ISO 9001 Certification in Philippines
CE Mark Certification in Philippines
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jobrxiv · 9 months
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Postdoc on single-cell and spatial omics of rare cancers International Agency for Research on Cancer Postdoc in the @CancersRare team @IARCWHO 🇺🇳 Lyon, France 🇫🇷 on single-cell and spatial omics of rare cancers See the full job description on jobRxiv: https://jobrxiv.org/job/international-agency-for-research-on-cancer-27778-postdoc-on-single-cell-and-spatial-omics-of-rare-cancers/?feed_id=68910 #bioinformatics #Cancer_Genomics #evolution #Single_Cell #spatial_transcriptomic #ScienceJobs #hiring #research
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leedsomics · 9 months
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Multi-Omics Profiling of Candida albicans Grown on Solid Versus Liquid Media
Candida albicans is a common pathogenic fungus that presents a challenge to healthcare facilities. It can switch between a yeast cell form that diffuses through the bloodstream to colonize internal organs and a filamentous form that penetrates host mucosa. Understanding the pathogen's strategies for environmental adaptation and, ultimately, survival, is crucial. As a complementary study, herein, a multi-omics analysis was performed using high-resolution timsTOF MS to compare the proteomes and... http://dlvr.it/T0b8Tr
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