#Lab-on-a-chip

[bpod-bpod]

Spread on Chips

A micropatterned chip that mimics the natural conditions of tumour spread into surrounding tissue in 3D. Invasive (metastatic) potential of cancer cells can be measured, and therapeutics screened

Read the published research article here

Still from a video from work by Smiti Bhattacharya and colleagues

Barbara T. Murphy Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York; Department of Mechanical Engineering, Columbia University, New York, NY, USA

Video originally published with a Creative Commons Attribution 4.0 International (CC BY-NC 4.0)

Published in Science Advances, August 2024

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[techninja]

Miniaturizing Innovation: Exploring the Microfluidics Market

In the realm of life sciences and healthcare, the Microfluidics market is emerging as a transformative force, enabling researchers and clinicians to miniaturize laboratory processes and revolutionize diagnostics and therapeutics. This article delves into the burgeoning field of microfluidics, its applications in biomedical research and diagnostics, and its potential to reshape the healthcare landscape.

Microfluidics, the science of manipulating fluids at the microscale, offers a versatile platform for a wide range of applications, from drug discovery and genomics to point-of-care diagnostics and personalized medicine. By leveraging the unique physics and mechanics of fluid flow at small scales, microfluidic devices enable precise control over sample volumes, reaction kinetics, and experimental workflows.

The Microfluidics market encompasses an extensive array of technologies, including lab-on-a-chip devices, microfluidic pumps, valves, and sensors, as well as integrated systems for automated sample preparation and analysis. These miniaturized platforms offer numerous advantages over traditional laboratory techniques, including reduced sample and reagent consumption, faster analysis times, and increased sensitivity and throughput.

One of the key drivers propelling the growth of the Microfluidics market is the increasing demand for point-of-care diagnostics and personalized medicine. Microfluidic devices enable rapid and cost-effective analysis of biological samples, allowing for early detection of diseases, monitoring of treatment efficacy, and tailoring of therapies to individual patient needs.

In addition to healthcare applications, microfluidic technologies are transforming the landscape of biomedical research, enabling researchers to conduct experiments with unprecedented precision and scalability. From studying cellular dynamics and microorganisms to exploring complex biological phenomena, microfluidic platforms offer insights that were previously inaccessible using conventional laboratory techniques.

Moreover, the integration of microfluidics with other emerging technologies, such as artificial intelligence (AI) and advanced imaging techniques, is expanding the horizons of biomedical research and diagnostics. By combining microfluidic devices with AI-powered analytics and high-resolution imaging systems, researchers can extract valuable insights from complex biological data with unprecedented speed and accuracy.

Want to learn more? Get Sample PDF Copy

As the Microfluidics market continues to evolve, collaboration between academia, industry, and healthcare providers will be essential to realize its full potential. Addressing challenges such as standardization, scalability, and regulatory compliance will be crucial to accelerating the adoption of microfluidic technologies across diverse applications and settings.

In conclusion, the Microfluidics market represents a paradigm shift in biomedical research and diagnostics, offering a powerful platform for innovation and discovery. With its ability to miniaturize laboratory processes, enhance analytical capabilities, and enable personalized healthcare solutions, microfluidic technology is poised to shape the future of medicine and healthcare delivery, driving advances that benefit patients, researchers, and clinicians alike.

[tapakah0]

WELL YOU KNOW WHAT I'M KISSING YOU REALLY HARD BECAUSE IT WAS IN FACT NOT, AT LEAST ONE OF HIS EYES IS OKAY AND ALL BODY PARTS ALSO

[fakesorbet]

happy pride month :]

[astrrorat]

CHILL SEASON

[abyssalzones]

there are so many things I both want and need to draw but it just hasn't been happening and I feel like I'm losing a race in my mind. which is fine

[levellabyrinth]

chirply chip ?

[frnkir]

thinking about how chase’s favorite cookie is sugar-free with chunks of carob, of course it’s so specific 😭🫶

[maeamian]

When I was a young excited physics student I went down to my advisor and asked for a job in a lab. Those of you who are in the sciences may recognize this as exceedingly common, most schools with science departments will hire undergrads for their labs both to give the undergrads experience and to have someone comparatively cheap to do the least skilled labor in those labs.

For me, the lab I was sent to was one doing cool photonics projects and I was assigned to a guy who was doing the theoretical modeling for them and I got put on a side project for them to develop a method to double check their results using Monte Carlo simulations.

Put bluntly, I toiled away in the little cubicle they had me in for about half a year before I transferred to a different school without ever having produced anything of any particular value other than a Monte Carlo simulation whose temperature readings were not taking into account the existence of a heat sink and therefore got overwhelmed by thermal photons in a completely inaccurate and unhelpful way.

Ultimately, many tasks, farmed out like this in a speculative way to undergrads, fail, certainly it's not exceptional that mine did and I learned a lot about the process in the process, so it wasn't wasted time for me, but it produced absolutely nothing the lab could use to further its results.

This is where it turns from a little anecdote about my work history into a morality tale, because what I have thus far deliberately failed to tell you is that the lab I was assigned to is a provider of radar services to the US Military. Had I produced anything of any value whatsoever the work I did would have been used by the US military to help with its capacity to deliver bombs. This is, unfortunately, as those of you who are in the sciences may recognize, also exceedingly common. Luckily, and through no foresight or moral thinking of my own, simply the inexperience of youth, I produced nothing of value but view the path they tried to set me down as a grim warning of what might have been.

I'm not asking for forgiveness, the harm I might have done was not done by me, although I'm also sure was done without my help. They didn't need it to be me they just needed someone with basic calculus knowledge who wouldn't think too hard about the connection between the work and the world, and they were happy enough that particular warm body was me.

So this is my plea, if you're young and getting involved in the sciences because you're passionate about knowledge and understanding our place in the universe. When you go to get that job in that lab that's such a good stepping stone to the next thing you want to do, take a second and look into where that lab's funding is coming from. If it turns out it's the military, maybe then take another second and really deeply consider what kind of thing your work can be used to do and if you would like some of the most bloodthirsty people on the planet to be able to do that thing because of your help.

I got lucky that I didn't help, but I'm hoping that with this warning you might be able to not help on purpose which is a greater moral good than what I managed.

[bpod-bpod]

On Your Nerves

Sensory neurons in our skin are the first to warn us about threats in the outside world. They relay temperature, pain and stress as electrical impulses fired towards the central nervous system, but these messages start at the fringe where skin meets nerve. To investigate further, scientists develop living models inside microfluidic devices. Green fluorescence highlights these rat nerve cells (with their DNA in blue) reaching out in three dimensions into a nurturing environment of chemicals, mimicking their natural extracellular matrix (ECM). Each column tests a different type of ECM, finding more developed growth on the right over 4 days (top to bottom). Later, the researchers grew skin cells down into the ECM to mingle with the nerve cells – similar to innervated skin. Such models could be used to test treatments for pain-related disorders, or mimic disorders like diabetic neuropathy.

Written by John Ankers

Image from work by Jinchul Ahn and Kyungeun Ohk, and colleagues

School of Mechanical Engineering, Korea University, Seoul, South Korea

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Nature Communications, March 2023

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[easeforall]

lab rats being vague about adam bree and chase’s creation is somewhat fair but introducing hundreds of bionic kids without explaining how krane managed to create or obtain all of them is inexcusable

[spikes-got-anger-issues]

Instead of remaking Lab Rats, how about we officially reboot Billion Dollar Freshman

[chipmooney]

more at http://www.instagram.com/chipmooney

[tessellated-sunl1ght]

One unexpected but fun outcome of me writing Fallen London fanfics is that I can actually trace my in-game progress with what I wrote my character doing.

[calebjorgens2024]

I’ve just had a recent dream regarding Tech, he was wearing a dark grey uniform of an imperial scientist with rank bar denoting his status as Imperial Commander and Science Officer. He was calmly adjusting his glasses as he typed out scientific diagrams regarding contraptions of any kind. This only fuels my plans to expand my Imperial Tech au! Once his chip activates. He’ll be more logically harsh in addition to being practical, cold, calculated, determined, firm, stern, serious, cunning, businesslike, persuasive, brutally honest, reasonable, brutally honest.

as such. The Amaxines, The Drengir are also involved in my Imperial Tech AU as is Phee Genoa. Case Solving is also included!

Not only that, I’ve recently dreamt Tech was giving new recruits for the Imperial Science Division a tour of his massive lab on Mt. Tantiss in addition to the others on Coruscant and Ziost!

[johnnycagesrightnut]

Thinking about the fact that in E-93742 Mason is Batman instead of Spider-Man which means he doesn’t have Juno which means he doesn’t have EITHER of his siblings

@johnnycagesleftnut lore, brother. Of my spidersona and this character I have based on you with the names you have selected