#laboratory automation

[wikipediapictures]

Proteomics

“TECAN Genesis 2000 robot preparing Ciphergen SELDI-TOF protein chips for proteomic pattern analysis. Highly accurate cancer prognosis can be accomplished by identifying protein patterns of specific cancers using this device.” - via Wikimedia Commons

[wissenresearchllc]

The global 𝐥𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐚𝐮𝐭𝐨𝐦𝐚𝐭𝐢𝐨𝐧 𝐦𝐚𝐫𝐤𝐞𝐭 is estimated at ~USD 5.4 billion in 2023 and is projected to reach ~USD 8.0 billion by 2030. The market is expected to grow at a CAGR of ~6.0% during the forecast period, 2024-2030. Click the link to access the Laboratory Automation Market report: https://lnkd.in/gQnQEBFH Request 𝐜𝐮𝐬𝐭𝐨𝐦𝐢𝐳𝐞𝐝 𝐫𝐞𝐩𝐨𝐫𝐭: https://lnkd.in/d6q8Q-5a 𝐊𝐞𝐲 𝐏𝐥𝐚𝐲𝐞𝐫𝐬 • ABBOTT LABORATORIES • THERMO FISHER SCIENTIFIC INC. • SIEMENS HEALTHINEERS • F.HOFFMANN-LA ROCHE LTD. • BECTON, DICKINSON AND COMPANY • DANAHER CORPORATION • HUDSON ROBOTICS INC. • TECAN GROUP LTD. 𝐑𝐞𝐜𝐞𝐧𝐭 𝐃𝐞𝐯𝐞𝐥𝐨𝐩𝐦𝐞𝐧𝐭𝐬 • ATS Corporation (Canada) acquired Heidolph Instruments (Germany) to strengthen its position in the life sciences and pharmaceutical industries. (August 2024) • Beckman Coulter Life Sciences (USA) partnered with Watchmaker Genomics (USA) to develop automated liquid handling solutions to enhance lab efficiency and consistency. (April 2024) • Clarapath (USA) partnered with the Mayo Clinic (USA) to advance lab automation, combining robotics, AI, and end-to-end automation to enhance tissue processing and improve patient care. (April 2024) • Abbott (USA) introduces GLP systems Track for laboratories in India to accelerate automation. (March 2024) For more details and personalized insights, reach out to us today! 𝐂𝐨𝐧𝐭𝐚𝐜𝐭: https://lnkd.in/gMPx_qnY 𝐄𝐦𝐚𝐢𝐥: info@wissenresearch.com

[lucykentor]

The 5 Biggest Trends in Lab Automation This Year

Laboratory automationplays a critical role in addressing these challenges, and the technology is rapidly advancing on several key fronts. This blog explores the top 5 trends shaping lab automation in 2024.

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[lorenzonuti]

Whispering secret data.

[root-analysis]

Laboratory Automation Market Size | Forecast Period | Share & Size (2035)

The global lab automation market (size) report is estimated to be USD 5.2 billion in 2022 and grow at an annualized rate (CAGR) of 13%. The Roots Analysis report features an extensive study of the current market landscape and the future potential of the lab automation market over the next 12 years. Get a detailed insights report now!

[kirby-the-gorb]

[theelementaryparticles]

Where does your lab work end up? In most large trauma hospitals and high volume medical laboratories, bloodwork will at some point end up on automated systems that identify patient demographics and ordered tests. The automation will process the samples appropriately, distributing them to various subsystems within the lab that analyze the blood. The completed samples are then filed in robotic archiving units for storage and eventual disposal.

[miscpav]

WANG TV Commercial - The Office Automation Computer Company - Feb 1983

[laboratory-equipment-supplier]

Advanced Pharmaceutical Testing Solutions by Gaia Science

In the pharmaceutical industry, stringent testing and quality control are essential to ensure that drugs are safe, effective, and meet regulatory requirements. The processes involved in testing and preparing pharmaceutical products play a significant role in ensuring that they deliver the desired therapeutic outcomes. Key elements in this process include dissolution testing, automated sample preparation, physical testing, and various specialized services. Gaia Science, a leader in providing advanced scientific solutions, offers a comprehensive range of equipment and services to meet the diverse needs of pharmaceutical companies. With a commitment to innovation and precision, Gaia Science is a trusted partner in pharmaceutical development and quality control.

Dissolution Testing: Ensuring Drug Efficacy and Safety

Dissolution testing is crucial in evaluating how a drug releases its active ingredients in the body. It provides insight into the rate and extent of drug absorption, which affects bioavailability and therapeutic effectiveness. Regulatory bodies like the FDA and EMA require detailed dissolution profiles for oral dosage forms to ensure that they meet the required standards for safety and efficacy.

Gaia Science provides a wide range of dissolution testing solutions, including:

• Fully-Automated Dissolution Tester: Designed for maximum efficiency, this system automates every aspect of dissolution testing, from sampling to analysis. It ensures high throughput and minimal human intervention, making it ideal for large-scale operations.

• Semi-Automated Dissolution Tester: Offers a balance between automation and manual control, allowing flexibility while still ensuring reliable results.

• Manual Dissolution Tester: For laboratories that require hands-on control, this option allows for precise manual operation, suitable for smaller-scale testing needs.

• Offline Dissolution Tester: Designed for labs that process samples offline, providing flexibility in workflow and sample management.

• UV Online Dissolution Tester: This advanced system uses UV detection to provide real-time analysis of dissolution samples, ensuring immediate feedback on drug release rates.

• UV On-/Offline Dissolution Tester: A versatile option that allows laboratories to switch between online and offline modes, providing greater flexibility in how samples are analyzed.

By offering these tailored solutions, Gaia Science ensures that pharmaceutical companies can choose the appropriate dissolution testing equipment based on their specific needs, improving testing efficiency and accuracy.

Automated Sample Preparation: Precision and Efficiency

Automated sample preparation is becoming an indispensable part of pharmaceutical analysis. With growing demands for faster and more accurate results, automation has become a key driver of efficiency and reproducibility in laboratories.

Gaia Science offers advanced automated sample preparation systems that streamline the preparation process for pharmaceutical analysis. These systems are capable of handling multiple tasks, including dilution, filtration, extraction, and mixing, which are essential in preparing samples for further testing. By automating these steps, Gaia Science’s solutions reduce the likelihood of human error, improve repeatability, and enhance laboratory throughput.

For pharmaceutical laboratories, these automated systems save time, lower costs, and ensure consistent, high-quality data. With modular designs, Gaia Science’s systems can be customized to meet specific testing requirements, making them versatile for a wide range of applications.

Physical Testing: Ensuring Product Integrity

The physical properties of pharmaceutical products are just as important as their chemical composition. Physical testing ensures that drugs can withstand the physical rigors of manufacturing, packaging, transportation, and storage while maintaining their efficacy. From tablets to capsules, each dosage form requires specific physical characteristics to ensure proper function.

Gaia Science offers a wide range of physical testing equipment, including:

• Friability Tester: Measures the tendency of tablets to break or crumble during handling and transportation. Ensuring tablets remain intact is critical for maintaining dosage accuracy.

• Tablet Disintegration Tester: Determines how quickly a tablet disintegrates in the body, a key factor in ensuring that the active ingredients are released at the correct rate.

• Tapped Density Tester: Measures the bulk density of powders to ensure consistent dosing and formulation.

• Cap Torque Tester: Tests the torque strength of bottle caps to ensure proper sealing and ease of opening by consumers.

• Hardness Tester: Evaluates the hardness of tablets to ensure they are strong enough to resist breaking, yet soft enough to disintegrate appropriately in the digestive system.

• Capsule Filler: Ensures consistent filling of capsules with active ingredients and excipients, ensuring uniform dosage across batches.

• Rotary Tablet Press: Used in tablet manufacturing to ensure that each tablet is compressed to the correct specifications.

• Weight Tester: Measures the weight of individual tablets or capsules to ensure consistency in dosage.

• Powder Flow Tester: Assesses the flow properties of powders to ensure they can be processed consistently during manufacturing.

These physical testing instruments from Gaia Science ensure that pharmaceutical products meet industry standards for quality and performance, preventing issues that could compromise the safety or efficacy of the drugs.

Comprehensive Pharma Services: Supporting Pharmaceutical Excellence

In addition to offering a range of advanced testing equipment, Gaia Science provides comprehensive pharmaceutical services to support every stage of the drug development and manufacturing process. These services include:

• Pharma Services: Gaia Science offers installation, calibration, validation, and maintenance services for all its equipment. Ensuring that laboratory instruments are properly calibrated and validated is essential for regulatory compliance and accurate results. Gaia Science’s team of highly trained professionals provides on-site support to ensure that all equipment is functioning optimally and meets the stringent standards required in pharmaceutical production.

• Training and Technical Support: Gaia Science provides comprehensive training and technical support to ensure that lab personnel are fully equipped to operate the equipment efficiently. Their experts work closely with clients to customize solutions that meet the specific needs of their operations.

• Customized Solutions: With a deep understanding of the pharmaceutical industry, Gaia Science offers customized solutions that cater to the unique needs of each laboratory. Whether it’s a small research lab or a large-scale manufacturing facility, Gaia Science tailors its products and services to provide maximum value.

Why Choose Gaia Science?

Gaia Science has established itself as a trusted partner for pharmaceutical companies looking for high-quality, reliable testing equipment and services. Their state-of-the-art technology, combined with unmatched customer support, ensures that pharmaceutical laboratories can meet the highest standards of quality and regulatory compliance. By offering innovative solutions in dissolution testing, automated sample preparation, and physical testing, Gaia Science helps companies streamline their processes and improve the accuracy of their results.

Conclusion

Dissolution testing, automated sample preparation and physical testing are essential processes in the pharmaceutical industry, ensuring that drugs are safe, effective, and of high quality. With Gaia Science’s advanced equipment and comprehensive services, pharmaceutical companies can confidently meet the demands of regulatory bodies while optimizing their workflows. Gaia Science’s commitment to innovation, precision, and customer support makes them a leader in providing scientific solutions to the pharmaceutical industry.

In Order To Find Out More Details On Scientific Laboratory Equipment Please Be Touch With Us Today Onwards..!

[pharmamachinerys-blog]

Capsule Filling Machine Australia: Revolutionizing Pharma Manufacturing

Australia’s pharmaceutical industry is rapidly evolving, with advanced machinery playing a pivotal role in ensuring efficiency, accuracy, and compliance. Among these machines, capsule filling machines stand out as essential equipment in pharmaceutical production. These machines streamline the process of encapsulating powders, granules, or liquids into capsules, ensuring high precision and productivity. In this blog, we’ll explore the benefits of capsule filling machines in Australia, their integration with other pharma equipment like laboratory freeze dryers, blister packaging machines, tray forming machines, and bottle filling machines for pharma, and why businesses are turning to reliable providers like Pharma Machinery.

The Role of Capsule Filling Machines in Pharmaceutical Manufacturing

Capsule filling machines are indispensable in both small-scale and large-scale pharma operations. Whether you’re producing nutritional supplements, over-the-counter medications, or prescription drugs, these machines ensure consistency in dosage, reduce manual intervention, and improve overall efficiency.

In Australia, where the pharmaceutical industry is heavily regulated, capsule filling machines help manufacturers meet stringent quality standards. Advanced machines can fill various capsule sizes and types, including hard gelatin and HPMC capsules, making them versatile tools for diverse applications.

Key features of modern capsule filling machines include:

High-Speed Operation: Capable of filling thousands of capsules per hour.

Precision Dosing: Ensures uniformity and minimizes wastage.

Ease of Use: User-friendly interfaces for quick setup and operation.

Compliance: Meets Good Manufacturing Practice (GMP) and Therapeutic Goods Administration (TGA) standards in Australia.

Integration with Other Pharmaceutical Equipment

To achieve seamless production, capsule filling machines are often used alongside other essential equipment. Here’s how these machines complement the broader pharmaceutical machinery ecosystem:

Laboratory Freeze Dryer Australia

Laboratory freeze dryers are crucial for stabilizing temperature-sensitive drugs, a common precursor step before encapsulation. By preserving the integrity of active pharmaceutical ingredients (APIs), freeze dryers ensure that the materials are ready for encapsulation in their most potent form.

In Australia, laboratory freeze dryers are in high demand for research and development purposes. Their integration with capsule filling machines allows manufacturers to transition smoothly from formulation to production.

Blister Packaging Machine

Once capsules are filled, they need secure and tamper-proof packaging. Enter the blister packaging machine. These machines create individual cavities for capsules, sealing them with a protective layer to ensure product integrity.

Blister packaging is especially beneficial for capsules as it provides:

Protection: Shields capsules from moisture, air, and contaminants.

Portability: Makes it easier for consumers to carry doses.

Visibility: Displays the product while maintaining its safety.

Blister packaging machines in Australia are increasingly being paired with capsule filling machines to create end-to-end production lines.

Tray Forming Machine

For manufacturers catering to bulk orders or specialized products, tray forming machines are another essential tool. These machines produce custom trays to hold capsules securely during storage or transport.

In a streamlined production line, tray forming machines come into play after capsules are filled and sorted, ensuring that every batch is organized efficiently.

Bottle Filling Machines Pharma

For products sold in bottles, bottle filling machines for pharma are the next logical step after capsule filling. These machines ensure that capsules are counted accurately and dispensed into bottles without manual handling.

Bottle filling machines in the pharmaceutical sector come equipped with advanced features like:

Automated Counting: Reduces errors and ensures precise quantities.

Customizable Bottle Sizes: Compatible with a variety of bottle shapes and sizes.

High-Speed Operations: Meets the demands of large-scale production.

Why Australian Manufacturers Choose Pharma Machinery

Choosing the right supplier for pharmaceutical equipment is crucial for manufacturers in Australia. Pharma Machinery has become a trusted name in the industry, offering cutting-edge solutions tailored to local regulations and market needs.

Comprehensive Product Range

From capsule filling machines to laboratory freeze dryers, blister packaging machines, tray forming machines, and bottle filling machines, Pharma Machinery offers a one-stop solution for all your pharma manufacturing needs.

Quality Assurance

All machines are designed to meet Australian standards, ensuring reliability, durability, and compliance with TGA guidelines.

Tailored Solutions

Whether you’re a small lab or a large pharmaceutical company, Pharma Machinery customizes its offerings to fit your production scale and budget.

Expert Support

The team provides end-to-end support, from installation and training to maintenance, ensuring that your operations run smoothly.

Future of Capsule Filling Machines in Australia

The demand for advanced capsule filling machines in Australia is poised to grow, driven by trends like personalized medicine, increased health awareness, and a focus on sustainability. Manufacturers are investing in energy-efficient and AI-driven machines to stay ahead of the curve.

Furthermore, the integration of IoT (Internet of Things) in pharmaceutical machinery is transforming operations. Modern capsule filling machines come with features like real-time monitoring, predictive maintenance, and data analytics, helping manufacturers optimize production and reduce downtime.

Conclusion

As Australia’s pharmaceutical industry continues to expand, capsule filling machines remain a cornerstone of efficient and compliant production. By integrating with other essential equipment like laboratory freeze dryers, blister packaging machines, tray forming machines, and bottle filling machines, these machines ensure a seamless manufacturing process from start to finish.

For businesses looking to invest in reliable and advanced pharma machinery, Pharma Machinery is the ideal partner. With a comprehensive range of products, expert support, and a commitment to quality, they are empowering Australia’s pharmaceutical industry to thrive in a competitive global market.

Invest in the future of your pharmaceutical production with cutting-edge capsule filling machines and complementary equipment today!

[lucykentor]

Retisoft Inc.'s Robotics and Automation Laboratory

Explore the future of science with Retisoft Inc.'s robotics and automation laboratory solutions. They empower researchers with cutting-edge technology, enhancing precision and efficiency in every lab process. Trust them for innovative solutions that redefine laboratory robotics and automation.

Visit:

[root-analysis]

Laboratory Automation Forecast Period : Key Drivers, Challenges, and Opportunities (2023-2035)

The global lab automation forecast period is estimated to be USD 5.2 billion in 2022 and grow at an annualized rate (CAGR) of 13%. The Roots Analysis report features an extensive study of the current market landscape and the future potential of the lab automation market over the next 12 years. Get a detailed insights report now!

[curiousquill1]

https://www.vjinstruments.com/products/dierollerextruder/

Dieroller Extruder: Precision Lab Equipment for Consistent Material Processing | VJ Instruments

Discover the Dieroller Extruder from VJ Instruments, a leading solution for efficient and precise material processing in laboratories. Engineered for optimal performance, our extruder ensures uniform mixing and shaping of materials, making it ideal for research and development in various fields. Explore the features that set our Dieroller Extruder apart, including adjustable speed settings and durable construction. Elevate your lab's productivity with cutting-edge technology designed for accuracy and reliability. Contact us today for more information!

[labotronic]

Automated Blood Culture System Weight 137 kgs

Labotronic Automated Blood Culture System is a non-invasive, fully automated microbial culture device. It features a 120-cell capacity designed with Swing shaking inculation with an incubation temperature of 35 °C ± 1.5 °C and an optical detection algorithm .

[pathologylab]

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[jcmarchi]

Precision home robots learn with real-to-sim-to-real

New Post has been published on https://thedigitalinsider.com/precision-home-robots-learn-with-real-to-sim-to-real/

Precision home robots learn with real-to-sim-to-real

At the top of many automation wish lists is a particularly time-consuming task: chores. 

The moonshot of many roboticists is cooking up the proper hardware and software combination so that a machine can learn “generalist” policies (the rules and strategies that guide robot behavior) that work everywhere, under all conditions. Realistically, though, if you have a home robot, you probably don’t care much about it working for your neighbors. MIT Computer Science and Artificial Intelligence Laboratory (CSAIL) researchers decided, with that in mind, to attempt to find a solution to easily train robust robot policies for very specific environments.

“We aim for robots to perform exceptionally well under disturbances, distractions, varying lighting conditions, and changes in object poses, all within a single environment,” says Marcel Torne Villasevil, MIT CSAIL research assistant in the Improbable AI lab and lead author on a recent paper about the work. “We propose a method to create digital twins on the fly using the latest advances in computer vision. With just their phones, anyone can capture a digital replica of the real world, and the robots can train in a simulated environment much faster than the real world, thanks to GPU parallelization. Our approach eliminates the need for extensive reward engineering by leveraging a few real-world demonstrations to jump-start the training process.”

Play video

Precision Home Robotics w/Real-to-Sim-to-Real Video: MIT CSAIL

Taking your robot home

RialTo, of course, is a little more complicated than just a simple wave of a phone and (boom!) home bot at your service. It begins by using your device to scan the target environment using tools like NeRFStudio, ARCode, or Polycam. Once the scene is reconstructed, users can upload it to RialTo’s interface to make detailed adjustments, add necessary joints to the robots, and more.

The refined scene is exported and brought into the simulator. Here, the aim is to develop a policy based on real-world actions and observations, such as one for grabbing a cup on a counter. These real-world demonstrations are replicated in the simulation, providing some valuable data for reinforcement learning. “This helps in creating a strong policy that works well in both the simulation and the real world. An enhanced algorithm using reinforcement learning helps guide this process, to ensure the policy is effective when applied outside of the simulator,” says Torne.

Testing showed that RialTo created strong policies for a variety of tasks, whether in controlled lab settings or more unpredictable real-world environments, improving 67 percent over imitation learning with the same number of demonstrations. The tasks involved opening a toaster, placing a book on a shelf, putting a plate on a rack, placing a mug on a shelf, opening a drawer, and opening a cabinet. For each task, the researchers tested the system’s performance under three increasing levels of difficulty: randomizing object poses, adding visual distractors, and applying physical disturbances during task executions. When paired with real-world data, the system outperformed traditional imitation-learning methods, especially in situations with lots of visual distractions or physical disruptions.

“These experiments show that if we care about being very robust to one particular environment, the best idea is to leverage digital twins instead of trying to obtain robustness with large-scale data collection in diverse environments,” says Pulkit Agrawal, director of Improbable AI Lab, MIT electrical engineering and computer science (EECS) associate professor, MIT CSAIL principal investigator, and senior author on the work.

As far as limitations, RialTo currently takes three days to be fully trained. To speed this up, the team mentions improving the underlying algorithms and using foundation models. Training in simulation also has its limitations, and currently it’s difficult to do effortless sim-to-real transfer and simulate deformable objects or liquids.

The next level

So what’s next for RialTo’s journey? Building on previous efforts, the scientists are working on preserving robustness against various disturbances while improving the model’s adaptability to new environments. “Our next endeavor is this approach to using pre-trained models, accelerating the learning process, minimizing human input, and achieving broader generalization capabilities,” says Torne.

“We’re incredibly enthusiastic about our ‘on-the-fly’ robot programming concept, where robots can autonomously scan their environment and learn how to solve specific tasks in simulation. While our current method has limitations — such as requiring a few initial demonstrations by a human and significant compute time for training these policies (up to three days) — we see it as a significant step towards achieving ‘on-the-fly’ robot learning and deployment,” says Torne. “This approach moves us closer to a future where robots won’t need a preexisting policy that covers every scenario. Instead, they can rapidly learn new tasks without extensive real-world interaction. In my view, this advancement could expedite the practical application of robotics far sooner than relying solely on a universal, all-encompassing policy.”

“To deploy robots in the real world, researchers have traditionally relied on methods such as imitation learning from expert data, which can be expensive, or reinforcement learning, which can be unsafe,” says Zoey Chen, a computer science PhD student at the University of Washington who wasn’t involved in the paper. “RialTo directly addresses both the safety constraints of real-world RL [robot learning], and efficient data constraints for data-driven learning methods, with its novel real-to-sim-to-real pipeline. This novel pipeline not only ensures safe and robust training in simulation before real-world deployment, but also significantly improves the efficiency of data collection. RialTo has the potential to significantly scale up robot learning and allows robots to adapt to complex real-world scenarios much more effectively.”

“Simulation has shown impressive capabilities on real robots by providing inexpensive, possibly infinite data for policy learning,” adds Marius Memmel, a computer science PhD student at the University of Washington who wasn’t involved in the work. “However, these methods are limited to a few specific scenarios, and constructing the corresponding simulations is expensive and laborious. RialTo provides an easy-to-use tool to reconstruct real-world environments in minutes instead of hours. Furthermore, it makes extensive use of collected demonstrations during policy learning, minimizing the burden on the operator and reducing the sim2real gap. RialTo demonstrates robustness to object poses and disturbances, showing incredible real-world performance without requiring extensive simulator construction and data collection.”

Torne wrote this paper alongside senior authors Abhishek Gupta, assistant professor at the University of Washington, and Agrawal. Four other CSAIL members are also credited: EECS PhD student Anthony Simeonov SM ’22, research assistant Zechu Li, undergraduate student April Chan, and Tao Chen PhD ’24. Improbable AI Lab and WEIRD Lab members also contributed valuable feedback and support in developing this project. 

This work was supported, in part, by the Sony Research Award, the U.S. government, and Hyundai Motor Co., with assistance from the WEIRD (Washington Embodied Intelligence and Robotics Development) Lab. The researchers presented their work at the Robotics Science and Systems (RSS) conference earlier this month.