#pencillin

[punkedsolar]

And that's a wrap for the first week of Funguary 2024 - the Celestial Fungi.

I usually overwork a lot of what I do (see my Kelpie picture) and have a deep and lingering terror of working quickly and then having to put an image down. So in my mind most of these are sketches rather than anything else. But I'm trying to let go of the need to be perfect, and accept the idea that art is still valuable even if it's not what I thought I'd get to.

The celestial themed fungi represented here are:

Mycena Subcyanocephala Lilac Coral Fungus Turkey Tail Cystolepiota Filoboletus Manipularis Angel Wings Penicillium

[cr1mson5returns]

I've had this idea for a hot minute that sometimes the Lazarus Pit causes people to spontaneously develop allergies they didn't previously have, and that's the story of how Jason became allergic to penicillin.

[professorgtnt]

有一個富有人家，到英國蘇格蘭渡假。有一天，他家小孩在游泳池忽然抽筋，大喊救命，附近一個農夫的兒子聽見了馬上跑過去，從水中將這小孩救起來，小孩的父親非常感謝這小農夫的善行。就問這位小農夫說：「你將來長大要做什麼呢？」回答：「我想是和我爸爸一樣耕田吧！」大人再問：「你有沒有想要改變做其他的嗎？他回答：「有的，我希望能當醫生，可是我家很窮，不可能讓我去學醫的。」被救孩子的父親說：「那好，你不必掛慮，讓我幫助你心裡的願望，照你的期待進行，我提供你一切學習的費用。」

這位農家小孩，就是後來發明盤尼西林的富萊明醫師，那位在游泳池被救的小孩，後來當英國首相名叫邱吉爾。

1943年12月邱吉爾在非洲北部訪問，忽然得肺病，他的醫生打電話回英國請富萊明醫師去急救。幾個小時之後，富萊明飛到非洲為他打針下藥，救了邱吉爾一命，邱吉爾向他道謝，富萊明笑著說：「不用謝，第一次是我救你的，這一次是你父親救了你。」

這位充滿愛心的農家小孩，巧遇一位充滿愛心、願意分享的富貴人家，真愛改變了他們的人生，也改變了世界。

一個是發明肺炎特效藥，拯救千千萬萬人的生命；另一個是領導英國，在第二次世界大戰後，走向富強勝利的大國。

[devilfic]

you know that scene where joel is torturing ellie’s kidnappers to find out where she is while the one guy in the back is begging for mercy and joel does a little smirk and says “you’re next” before stabbing the other one in the knee? that scene? yeah it’s gonna keep me up all night

[felidaefatigue]

started watercolour pencillin a lil chappell roan on my lunch today cause I seen a concert pic from secretofmim on insta and the lighting was stunningg.

[nerdgirlnarrates]

Flucloxacillin: another pencillin, this time the most commonly prescribed narrow-spectrum penicillinase-resistant penicillin in the UK. Apparently, it was not marketed much in the US and Canada, where dicloxacillin filled its role. Flucloxacillin is used almost exclusively for gram positive infections, especially Staph aureus, though it can be also be used for pre-op prophylaxis.

Zosyn (pip/tazo): One of the big guns. Like augmentin, this combo therapy includes both a penicillin and a beta-lactamase inhibitor; unlike augmentin, it covers pseudomonas. Zosyn is crucial for treating nosocomial infections and often one of the first drugs we reach for when empirically broadening antibiotics. It is also first line for neutropenic fever.

Vote for the best antibiotic

[knelly713]

Day 7 of Funguary 2024 hosted by @feefal - Pencillin

[flyonthewallmedstudent]

Chlamydia Trachomatis

Can't blog about gonorrhoea without at least a brief mention about Chlamydia.

Risk groups: Sexually active and under 30 Concerningly, it's usually asymptomatic (90% are asymptomatic), but can have severe/significant complications if undetected and untreated (i.e. infertility, pelvic inflammatory disease etc.)

Prevention: Active screening of anyone under <30, pregnant patients in clinic etc. Related to Chlamydophila Pneumoniae (atypical 'walking' pneumonia) and Psittaci (bird infection, causes resp illness psittacosis) Is an atypical bacteria, no cell wall, so penicillins have no effect. It has a lipid rich membrane. Gram stains negative (Pink), much like gono. Clinical presentation: Source: QHealth

ANyone with a human body can also get laryngeal chlamydia (so painful throat) from oral sex, and conjunctivitis (similarly, oral sex)

IMage source:

Pregnant women are routinely screened and treated, as it can also result in neonatal conjunctivitis during vaginal delivery, usually presenting 2 weeks post partum.

by the way, koalas also get chlamydia..

Investigations: - gold standard testing is PCR swab or NAAT (Nucleic acid amplification test) Also test for: - concurrent gonorrhoea (treated with ceftriaxone)

Complications if left untreated: Pregnancy: low birth weight infants, pre term delivery, as above, neonatal conjunctivitis Pelvic inflammatory disease --> which can lead to abscess and infertility via tubal damage from inflammation

Epididymo-orchitis --> painful, swollen testicles, can feel like a testicular torsion presentation is a differential for this

Rarely, but can happen: reactive arthritis. painful, red, hot swollen joints from immune complexes, sterile on testing fluid MCS from joint. usually resolving post infection, even more rarely can lead to long term inflammatory arthritis needing long term immunosuppression as guided by rheumatology. Treatment: 1 g of azithromycin as a stat dose, PO (blissfully simple) alternative is doxycyline 100 mg BD for a week, but I rarely see this prescribed. Given it is an atypical that won't respond to pencillins or cephalosporins. For adherence it's better to just go with the stat dose unless there's contraindications to azith (prolonged QTc etc). As it often co-occurs with gono, they're often tested together and treated together. With gono it's IM cef, 500 mg

Contact tracing is always incredibly important in STIs - need to trace back partners up to 6 mos Sexual contact - none for 7 days post therapy, and not with partners from the last 6 months until they've been screened and treated if positive. there's no immunity post infection, and re-infection is common. interestingly re testing at 3 months is recommended.

REsource: JAMA

CDC guidelines/free Free - Australian STI guidelines

Summary from JAMA on X:

[spumonie]

i do wish minor adult fixes didn't take so much time. i should be able to buy pencillin over the counter and change my phone protector at the same time

[amazingfacts2166]

interesting history facts discovery of pencillin पेनिसिलिन#youtubeshorts...

[registerednursern]

Cephalosporin Nursing Antibiotic Pharmacology Review

This is a large group of beta-lactam antibiotics used to target a variety of gram-positive and gram-negative bacteria. There are five generations of Cephalosporins currently. These antibiotics are similar to another group of beta-lactam antibiotics called the Pencillins. Their similarity arises from their chemical structures because both types are made up of a beta-lactam ring. Due to this,…

[homeolab]

Homeopathic Medicine For Allergy

Allergy: - The word sensitivity was first utilized by Van Pirket when an individual feels debilitated because of contact with an outer substance. Sensitivities happen when an individual's resistant framework erroneously accepts that something they have interacted with or eaten is hurtful.

Our body produces antibodies to safeguard the body. Antibodies inspire the body's energy cells to send different synthetics into the blood, one of which is histamin.

Histamin follows up on the eyes, throat, lungs, skin and furthermore delivers side effects of a hypersensitive response. At the point when the body produces antibodies against the allergen, which perceives the allergen created and the body begins delivering histamin into the blood.

Are allergy hereditary?

Certain individuals have it from birth since it is acquired. Young men have more hereditary sensitivities than young ladies.

various kinds of allergy

Many kinds of food sources, synthetics, residue and bloom dust, and so on can all cause sensitivities.

Kinds of allergy in view of substances

Food Sensitivity: 2 to 3 percent of grown-ups and around 8% of kids in India are impacted by food sensitivities. Sensitivities have been found to wheat, millet, soyabean, eggs, fish, and milk items and assuming we discuss a few vegetables, instances of brinjal, okra have likewise been noticed.

Side effects of food allergy

regurgitating and looseness of the bowels

stomach agony or stomach cramps

loss of craving

decline in circulatory strain

Preventive measures: -

Those things which are unfavourably susceptible ought to be stayed away from or treated for it.

Stomach allergy ➖

Creature skin, fur, and proteins are totally called allergens, they can cause sensitivities. The fur of creatures loads up with dust and other allergenic substances, which genuinely influence allergy. The majority of individuals experiencing sensitivities are additionally susceptible to pets.

Side effects of stomach allergy:- Redness or tingling under the eyelids and nose.

Avoidance: On the off chance that you are impacted by this kind of sensitivity, don't come in that frame of mind with creatures or on the other hand on the off chance that you are coming, clean up with a cleanser.

Allergy to residue or residue: -

In view of the measurements, the greater part of individuals (around 80%) who are hypersensitive victims will be survivors of this sensitivity, or at least, they are susceptible to tidy.

Side effects of residue allergy  :- Tears moving from the eyes, their redness, tingling in them, or watery nose, tingling in the nose.

Ways of staying away from dust allergy: -

Keep away from dust and so on. Try not to go to where a ton of residue is emerging.

As per the information:-

Around 25% of the Indian public is experiencing sensitivities, out of which five percent of individuals who have sensitivities transform into asthma.

This figure expansions in summer on the grounds that the allergens and aggravations present in the climate like residue, dust, and so on are delivered in enormous amounts.

In the event that the mother or father of the youngsters is experiencing sensitivities, there is a half opportunity that this sensitivity can likewise come in their kids.

On the off chance that both mother and father are hypersensitive, there is a 75% opportunity that the youngster will likewise experience the ill effects of sensitivities.

Allergy treatment with homeopathic medication

Homeopathic medication can end up being extremely compelling for the treatment of sensitivity victims on the grounds that homeopathic medication is made normally, or at least, the materials utilized in it are taken from nature.

Best homeopathic medication for allergy:-

The name of a homeopathic medication that can end up being generally excellent for your allergy is that DROX 30 PENCILLIN (Allergy).

 it is produced by the haslab organization. This medication has ended up being extremely viable for a huge number of individuals. By utilizing this medication, you also can treat your sensitivities appropriately.

[lucivetta-blanca]

A messy little doodle. She's lost in thought~ #art #artistsoninstagram #artwork #drawing #drawingsketch #pencil #pencilartwork #pencilart #pencildrawing #pencillineart #pencillines #pencilsketch #sketch #doodle #doodlesketch #dreamy #dreamyart #messysketch https://www.instagram.com/p/COtEGBNnepM/?igshid=56595zdvtjo9

[gottagobuycheese]

one thing that I’m very glad never fails to turn into a type 2 funny (i.e. very Not Fun in the moment, but hilarious afterward) is when you’re being asked about something perfectly reasonable and but can’t remember a single relevant thing about it. just like, total mind blank. favorite character? impossible, you’ve never consumed any media with characters in it, ever, or any media at all for that matter. write whatever you want for the next 60 seconds? ridiculous, you’ve never strung a sentence together before in your life. a word that starts with “i”? I, THE SUBJECT OF THIS SENTENCE, DO NOT KNOW A SINGLE WORD THAT BEGINS WITH THE LETTER I. INCREDIBLE. 

[stevenegordon]

A #JeanGrey #pencilline #commission #xmenevolution #characterdesign #pencilart https://www.instagram.com/p/CC_enmNg0nr/?igshid=ijwg5e8619z1

[lisangart]

04/03/2021 Working on another bigger one. At that stage where the architectural elements are mapped out, just getting rid of those pesky pencil lines at the moment. Every step of the process plays a part and is all very important! #artprocess #artstuff #artjournal #pencillines #drawing #eraser https://www.instagram.com/p/CNOeQ_ag0QD/?igshid=gdkv8mm212h4