#Bioavailability

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The Incredible Health Benefits of Curcumin: A Powerful Natural Remedy

Curcumin, the active compound found in turmeric (Curcuma longa), has been used for centuries in Ayurvedic and traditional medicine for its anti-inflammatory, antioxidant, and healing properties. Modern science has confirmed many of these benefits, making curcumin one of the most studied natural health supplements today. Below, we explore the top health benefits of curcumin and how it can…

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Magnesium is an important mineral that helps our body work properly. It is needed for more than 300 processes in the body, like making energy, building proteins, and keeping our muscles and nerves healthy. It also helps control blood pressure, blood sugar, and even helps make DNA, which is important for our health.

Magnesium is found in many foods, such as leafy greens, nuts, seeds, and whole grains. But some people don’t get enough magnesium from their food, which can be a problem. Things like drinking too much alcohol, taking certain medicines, or having health problems can make magnesium levels too low. Because of this, some people take magnesium supplements to stay healthy.

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[ingredientsonline]

Why Better Bioavailability Matters: Maximizing Absorption Efficiency

In health and nutrition, one crucial element for achieving the best results is bioavailability. This concept describes how well the body absorbs and uses nutrients from the foods and supplements we take. If absorption is inadequate, even the most nutrient-dense products may not provide their complete advantages. This article delves into the importance of enhanced bioavailability and how optimizing absorption can reveal the full benefits of essential nutrients for better health and wellness. Click here to learn more.

[maxicuma]

FAQs on Turmeric Curcumin Benefits, Bioavailability

Have questions about Maxicuma? Our FAQs page covers topics like product usage, benefits, and technology. Get informed quickly.

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Science Behind Spheronization: Why Shape Matters in Pharmaceutical Production

The pharmaceutical manufacturing world is pretty complex. The size of the particles is one prime consideration that can make a world of difference in achieving quality and effective medicines. At the core of it lies spheronization—the process of converting raw material into uniform spherical particles in order to improve the production efficiency and performance of the final drug product.

Awareness: Spheronization and Its Implication in the Pharmaceutical Industry

Spheronization refers to an advanced pelletizing technique that results in creating nearly round particles from a powder, granules, or other forms of solid. One can even control the process of production by changing the process variable inside a spheronizer. The size distribution is narrow and specific to formulation requirements for spherical particles resulting from the spheronizer.

So why does this round shape make so much difference in pharmaceutical? This is basically because the physical properties are unique which the spherical particle possesses. Compared with irregular particles, the spherical particle has the flowability feature. For this reason, it could easily feed to the equipment smoothly and with consistency—the tableting equipment, and the encapsulation equipment for that matter. It can be compressed to a considerable pressure, hence making sturdy, excellent tablets, capsules, and so forth.

Ultimately, the spherical shape unlocks major benefits through the entire pipeline of pharmaceutical production, from streamlining manufacturing processes to improving quality and performance of the final drug product. That is why spheronization has become an indispensable tool in the modern pharmaceutical industry.

Consideration: Technical Advantages of Spherical Particles

The very simple yet highly creative process on which lies the heart of spheronization involves taking pharmaceutical powders or granules and introducing them to the particular equipment like the spheronizer. Once this is done, a controlled rotation, coupled with friction, ensues, and the smooth agitation makes the particles turn into almost perfect spheres because of a gradual process of forming rounded shapes.

There are many technical advantages of the spherical shape per se. First, an ideally uniform particle size as well as a relatively smooth surface renders spheres better flow and handling properties which are really of great importance for assured dosing that is reproducible in the process of tabletting, encapsulation, or other types of filling operations. This sort of fluidity allows fewer stops of machinery, decreased scrap, and therefore generally increased output.

However, the advantages of spheronization go far beyond making a production process easier. The round shape also plays a very important role in performance and stability of the drug product in the end. Spherical particles are usually characterized by more favorable dissolution profiles and have drug release kinetics that are predictable and reproducible. Further, the size and distribution of spheronized particle sizes may also stabilize the physical properties of formulation, reducing the possibility of segregation or caking over time during storage and shipping.

Conclusion: Practical Applications of Spheronization Technology

The versatility of spheronization technology makes it a valuable tool for a range of pharmaceutical applications. The ability to produce high-quality, spherical particles is one of the key enablers for manufacturers looking to provide effective and reliable drug products for patients—from immediate-release tablets to controlled-release beads.

Another excellent use of spheronization is in multiparticulate drug delivery systems. Uniform spherical pellets or minitablets formed with the help of a dedicated spheronizer allow the formulator to design complex release profiles suitable for the particular physiological requirements of the patient. This precision, as one might expect, is directly translatable into improved clinical performance and patient experience.

There are many other applications where it extends far beyond the drug. Thus, manufacturing fertilizers produce spherical granules, which can improve spreading while reducing dust and will be efficient to apply without creating hazards on workers' safety. For the sphere in ceramics or abrasives, it would increase polishing performance and lessen the amount of wear of the machines.

By passage of time, its importance will continue to augment amongst the pharmaceutical industries about this spheronization technology. Through the application of principles and scientific knowledge for developing uniform, spherical particles to manufacture through a specialized machine that reduces the production line's steps and increases product quality in a final healthcare delivery line that benefits patient well-being.

In situ, raw materials are to be shaped into uniform performing particles—a vital part of the contemporary pharmaceutical arsenal with more complex drug formulations bringing a demand for improvement and spheronization. Total control by pharmaceutical companies in the science behind such a process will unlock new dimensions that can further efficiency, quality, and innovation—all within improved safety and efficacy for patients in medical treatments.

[openintegrative]

ALA vs. DHA & EPA Omega-3: Why Source Matters

ALA (Alpha-Linolenic Acid) is found in flaxseeds, chia seeds, and walnuts, but converts poorly to DHA and EPA.

DHA and EPA are critical long-chain omega-3s found in animal sources like fatty fish and are essential for brain and heart health.

The body converts ALA to DHA and EPA inefficiently, with conversion rates often less than 10%.

Direct consumption of DHA and EPA from animal sources is more effective for meeting nutritional needs.

Vegans may need to rely on algal oil to obtain sufficient DHA and EPA.

Introduction

Omega-3 fatty acids are vital for numerous bodily functions, particularly brain and heart health.

There are different types of omega-3s, with ALA being a short-chain omega-3 found in plant foods, and DHA and EPA being long-chain omega-3s primarily sourced from animal products.

Understanding the differences between these fatty acids is important, especially for those following specific dietary preferences like veganism.

Overview of ALA (Alpha-Linolenic Acid)

ALA is a plant-based omega-3 fatty acid commonly found in foods like flaxseeds, chia seeds, and walnuts.

While ALA plays a role in maintaining overall health, it must be converted into DHA and EPA—forms of omega-3 that the body can directly utilize.

Unfortunately, the conversion rate of ALA to DHA and EPA is often less than 10%, making it a less efficient source of these critical nutrients.

DHA (Docosahexaenoic Acid) and EPA (Eicosapentaenoic Acid)

DHA and EPA are long-chain omega-3 fatty acids predominantly found in animal sources, such as fatty fish, cod liver oil, and organ meats.

These omega-3s are essential for brain function, heart health, and reducing inflammation.

Unlike ALA, DHA and EPA are directly available for the body to use, making them more effective at supporting these critical bodily functions.

Bioavailability and Nutritional Impact

The bioavailability of omega-3s refers to how well the body can absorb and use these nutrients.

ALA has lower bioavailability due to the inefficient conversion process, which means the body struggles to get enough DHA and EPA from ALA alone.

In contrast, DHA and EPA from animal sources are highly bioavailable, providing immediate nutritional benefits without the need for conversion.

Health Implications

Relying solely on ALA for omega-3 intake can lead to deficiencies in DHA and EPA, which are vital for cognitive health, cardiovascular function, and inflammation control.

Adequate intake of DHA and EPA has been linked to reduced risks of heart disease, improved brain health, and better inflammatory responses.

Vegans who do not consume DHA and EPA from animal sources may face health challenges if they don’t supplement properly.

Vegan Alternatives and Considerations

Vegans looking to meet their omega-3 needs can turn to algal oil, a plant-based source of DHA and EPA.

While algal oil can provide these essential fatty acids, it may not be as easily accessible or affordable as traditional animal sources.

Despite this, it remains the best option for vegans who want to ensure they receive adequate amounts of DHA and EPA.

Conclusion

ALA, DHA, and EPA are all important omega-3 fatty acids, but they differ significantly in their sources, bioavailability, and effectiveness. For those following a vegan diet, understanding the limitations of ALA and the necessity of supplementing with DHA and EPA is crucial for maintaining optimal health. Animal-based omega-3s remain the most efficient and effective source, but with careful planning and supplementation, vegans can also meet their omega-3 needs.

FAQ

What are the best vegan sources of ALA?

Flaxseeds, chia seeds, and walnuts are among the richest sources of ALA.

Can ALA fully replace DHA and EPA in a vegan diet?

No, due to low conversion rates, ALA cannot fully replace DHA and EPA.

Are there vegan sources of DHA and EPA?

Yes, algal oil is a vegan source of DHA and EPA.

What happens if I don’t get enough DHA and EPA?

Insufficient intake can affect brain function, heart health, and inflammation levels.

Is it necessary to supplement with DHA and EPA if I’m vegan?

Yes, supplementation with algal oil is recommended to ensure adequate intake.

Research

Attar-Bashi, N.M., Weisinger, R.S., Begg, D.P., Li, D. and Sinclair, A.J., 2007. Failure of conjugated linoleic acid supplementation to enhance biosynthesis of docosahexaenoic acid from α-linolenic acid in healthy human volunteers. Prostaglandins, Leukotrienes and Essential Fatty Acids, 76(3), pp.121–130.

Baker, E.J., Miles, E.A., Burdge, G.C., Yaqoob, P. and Calder, P.C., 2016. Metabolism and functional effects of plant-derived omega-3 fatty acids in humans. Progress in Lipid Research, 64, pp.30–56.

Brenna, J.T., Salem, N., Sinclair, A.J. and Cunnane, S.C., 2009. α-Linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans. Prostaglandins, Leukotrienes and Essential Fatty Acids, [online] 80(2–3), pp.85–91. https://doi.org/10.1016/j.plefa.2009.01.004.

Burdge, G.C., 2006. Metabolism of α-linolenic acid in humans. Prostaglandins, Leukotrienes and Essential Fatty Acids, 75(3), pp.161–168.

Burdge, G.C. and Calder, P.C., 2005. α‐Linolenic acid metabolism in adult humans: the effects of gender and age on conversion to longer‐chain polyunsaturated fatty acids. European Journal of Lipid Science and Technology, 107(6), pp.426–439.

Burdge, G.C. and Calder, P.C., 2006. Dietary α-linolenic acid and health-related outcomes: a metabolic perspective. Nutrition Research Reviews, 19(1), pp.26–52.

Burdge, G.C. and Wootton, S.A., 2002. Conversion of α-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women. British Journal of Nutrition, 88(4), pp.411–420.

Burdge, G.C., Jones, A.E. and Wootton, S.A., 2002. Eicosapentaenoic and docosapentaenoic acids are the principal products of α-linolenic acid metabolism in young men. British Journal of Nutrition, 88(4), pp.355–363.

Chen, H., Deng, G., Zhou, Q., Chu, X., Su, M., Wei, Y., Li, L. and Zhang, Z., 2020. Effects of eicosapentaenoic acid and docosahexaenoic acid versus α-linolenic acid supplementation on cardiometabolic risk factors: a meta-analysis of randomized controlled trials. Food & Function, 11(3), pp.1919–1932.

Egert, S., Kannenberg, F., Somoza, V., Erbersdobler, H.F. and Wahrburg, U., 2009. Dietary α-Linolenic Acid, EPA, and DHA have differential effects on LDL fatty acid composition but similar effects on serum lipid profiles in normolipidemic humans. The Journal of Nutrition, 139(5), pp.861–868.

Fleming, J.A. and Kris-Etherton, P.M., 2014. The evidence for α-linolenic acid and cardiovascular disease benefits: comparisons with eicosapentaenoic acid and docosahexaenoic acid. Advances in Nutrition, 5(6), pp.863S-876S.

Gerster, H., 1998. Can adults adequately convert α-linolenic acid (18: 3n-3) to eicosapentaenoic acid (20: 5n-3) and docosahexaenoic acid (22: 6n-3)?. International Journal for Vitamin and Nutrition Research, 68(3), pp.159-173.

Gibson, R., Neumann, M., Lien, E., Boyd, K., & Tu, W., 2013. Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids. Prostaglandins, Leukotrienes and Essential Fatty Acids, 88(1), pp.139-146.

Gibson, R.A., Muhlhausler, B. and Makrides, M., Conversion of linoleic acid and alpha-linolenic acid to long-chain polyunsaturated fatty acids (LCPUFAs), with a focus on pregnancy, lactation and the first 2 years of life. Maternal & Child Nutrition, 7, pp.17-26.

Goyens, P.L., Spilker, M.E., Zock, P.L., Katan, M.B. and Mensink, R.P., 2006. Conversion of α-linolenic acid in humans is influenced by the absolute amounts of α-linolenic acid and linoleic acid in the diet and not by their ratio. The American Journal of Clinical Nutrition, [online] 84(1), pp.44–53. https://doi.org/10.1093/ajcn/84.1.44.

Greupner, T., Kutzner, L., Nolte, F., Strangmann, A., Kohrs, H., Hahn, A., Schebb, N.H. and Schuchardt, J.P., 2018. Effects of a 12-week high-α-linolenic acid intervention on EPA and DHA concentrations in red blood cells and plasma oxylipin pattern in subjects with a low EPA and DHA status. Food & Function, [online] 9(3), pp.1587–1600. https://doi.org/10.1039/c7fo01809f.

Liou, Y.A., King, D.J., Zibrik, D. and Innis, S.M., 2007. Decreasing linoleic acid with constant α-linolenic acid in dietary fats increases (n-3) eicosapentaenoic acid in plasma phospholipids in healthy men. The Journal of Nutrition, 137(4), pp.945–952.

Mantzioris, E., James, M., Gibson, R. and Cleland, L., 1995. Differences exist in the relationships between dietary linoleic and alpha-linolenic acids and their respective long-chain metabolites. The American Journal of Clinical Nutrition, 61(2), pp.320–324.

Rapoport, S.I., Rao, J.S. and Igarashi, M., 2007. Brain metabolism of nutritionally essential polyunsaturated fatty acids depends on both the diet and the liver. Prostaglandins, Leukotrienes and Essential Fatty Acids, [online] 77(5–6), pp.251–261. https://doi.org/10.1016/j.plefa.2007.10.023.

Salem, N. and Eggersdorfer, M., 2015. Is the world supply of omega-3 fatty acids adequate for optimal human nutrition?. Current Opinion in Clinical Nutrition and Metabolic Care, 18(2), pp.147–154.

Takic, M., Pokimica, B., Petrovic-Oggiano, G. and Popovic, T., 2022. Effects of dietary α-linolenic acid treatment and the efficiency of its conversion to eicosapentaenoic and docosahexaenoic acids in obesity and related diseases. Molecules, 27(14), p.4471.

Wendland, E., 2006. Effect of α-linolenic acid on cardiovascular risk markers: a systematic review. *Heart*, 92(2), pp.166–169.

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Maximizing CBD Absorption with Pure for Life™ 🌿💧

Want to ensure you’re getting the full benefits of your CBD? Understanding bioavailability is key! We dive into the science of CBD absorption and explore cutting-edge methods like lipid-based formulations and solid-state technologies to improve effectiveness. Learn how Pure for Life™ is revolutionizing CBD absorption. 🌟

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Enhancing Food Texture: How ELASTOVIN Adds Springiness to Noodles and Firmness to Eggless Cakes

In the ever-evolving food and pharmaceutical industries, the need for effective encapsulation and emulsification is crucial for product innovation and quality. EMULCOAT stands out as a versatile solution, playing a pivotal role in enhancing product formulations by improving stability, solubility, and the delivery of active ingredients. Whether in food applications or pharmaceutical and nutraceutical products, EMULCOAT offers a multifaceted approach to formulation challenges.

What is EMULCOAT?

EMULCOAT is a specialized emulsifier and encapsulating agent designed for a variety of applications. Its ability to encapsulate flavors, vitamins, spices, and even fatty esters makes it an invaluable ingredient in the food industry. It ensures that flavors and nutrients are effectively delivered without losing potency or degrading over time.

In the pharmaceutical and nutraceutical industries, EMULCOAT’s ability to act as both an emulsifier and solubilizer is a game-changer. It is widely used in formulations such as excipients, granules, pellets, suspensions, and liquids, ensuring the efficient delivery of active ingredients while maintaining stability and consistency throughout the product's shelf life.

Encapsulation in Food Applications

Encapsulation is critical for protecting sensitive ingredients like flavors, vitamins, and spices from external factors such as oxidation or moisture, which could degrade their quality. EMULCOAT excels in this area by forming a protective coating around these ingredients, preventing premature degradation and ensuring they remain stable until consumption.

In addition to encapsulation, EMULCOAT enhances the product's appearance by forming stable clouds in beverages, giving them a uniform, appealing look. This is especially useful in drinks that aim to deliver a visually pleasing product while also ensuring the even distribution of ingredients like vitamins and flavors.

Emulsification and Solubilization in Pharmaceuticals

In pharmaceutical and nutraceutical applications, EMULCOAT serves as an essential emulsifier and solubilizer. Many active ingredients in pharmaceutical formulations are hydrophobic, meaning they do not easily dissolve in water. EMULCOAT solves this problem by enabling the solubilization of these ingredients, allowing them to mix properly in liquid formulations like syrups, suspensions, and even in solid forms like pellets and granules.

By improving the bioavailability of active compounds, EMULCOAT ensures that medications and supplements deliver their intended effects efficiently. It also plays a crucial role in stabilizing formulations, preventing ingredients from separating, which is essential for both the quality and safety of the final product.

EMULCOAT’s versatility as an encapsulating and emulsifying agent makes it a valuable ingredient in both the food and pharmaceutical industries. Its ability to stabilize, protect, and enhance the delivery of flavors, vitamins, and active ingredients ensures product consistency and quality, helping manufacturers meet consumer demands for both taste and efficacy. With its broad range of applications, EMULCOAT is a solution that enables innovation across multiple sectors.

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[naturalfactorsb]

Your Guide to Curcumin Absorption: How to Maximize Its Benefits

Have you ever drunk a peppery turmeric latte and wondered, “what’s the point?” We’re debunking turmeric myths so you can get back to your ordinary chai latté!

KATE RHÉAUME, ND 

Native to Southeast Asia, turmeric has been used for health, culinary, and ceremonial purposes for almost 4,000 years and has at least 53 different names in Sanskrit.1 Its scientific name is Curcuma longa.1

This flowering plant is a member of the same family as ginger and possesses a root-like stem that produces a brilliant golden yellow spice. Since ancient times, its bright colour and widespread use as fabric dye and cooking spice earned it the nickname “Indian saffron,” although the plant is unrelated to true saffron.1

Today, the popularity of turmeric has reached celebrity status, with widespread rumours and misinformation to match. Here’s what you need to know about turmeric, and its key active constituent, curcumin, to really benefit from this ancient and ever-popular botanical. 

Curcumin Research Revealed 

With such a long history of use, it’s not surprising that turmeric has been the subject of thousands of scientific papers. More than 100 components have been isolated from turmeric, the most attention grabbing of which is curcumin.

The technical and far less catchy name for curcumin is diferuloylmethane. The health benefits that people seek from turmeric really come from this compound, which is well established as an effective antioxidant and for its unparalleled ability to promote a healthy inflammatory response. 

When it comes to promoting a healthy inflammatory response, curcumin is no one-trick pony. Once absorbed, curcumin works on multiple pathways, including transcription factors, cytokines, protein kinases, adhesion molecules, and enzymes.

It helps maintain a stable balance of signalling molecules. In turn, this aids in mitigating the cascade of biological compounds responsible for occasional discomfort. 

As for oxidative stress, curcumin defends against both fat- and water-soluble free radicals.2 Since free radicals play a role in most health conditions, curcumin is a shining star of well-being and health resilience. 

Curcumin Myths Debunked 

There is usually some erroneous hearsay around anything highly sought after; curcumin is no exception. One of the most prevalent curcumin myths is that you can reap the benefits of curcumin by just sprinkling a little on your food, enjoying a turmeric latté, or eating curry occasionally. The truth is, in its natural state, curcumin is a large, irregular molecule that is simply not readily absorbed in the human digestive tract. In other words, it naturally has low bioavailability.

In studies, 10–12 g of curcumin were administered by mouth, and participants showed little change in blood levels.3 The full benefits of curcumin are only realised through absorption enhancement, and how best to do this is the most rampant curcumin misinformation of all. 

The single biggest myth about curcumin is that it requires black pepper for best absorption. Everyone has heard this; it is the subject of memes and even a few stand-up comedy routines. This particular misinformation is based on a 1998 study in which researchers tried to overcome curcumin’s notoriously low absorption.

As expected, study participants given standard curcumin had basically undetectable blood levels of curcumin. Participants given curcumin and black pepper extract (piperine) achieved blood levels that were just barely detectable, and this was deemed a significant increase in absorption over standard curcumin!4 However, the absolute value of the blood levels in the curcumin and black pepper group was nothing to celebrate, yet the advice has unfortunately stuck. 

Curcumin Absorption at Last 

If black pepper and turmeric lattés don’t work, then what does? Poor absorption is the main reason for lacklustre clinical studies using regular curcumin, even when given in substantial doses.

Curcumin absorption can be bolstered using a few methods, but they are not all equal. There is one enhanced-absorption form of curcumin that has been used in the greatest number of successful published and ongoing clinical studies, called Theracurmin®.

Theracurmin® is an advanced formulation that uses proprietary dispersion technology to create microscopic particles dispersed in a colloidal suspension for better absorption. What does that mean in plain language? Simply put, standard curcumin is ground into extremely fine particles, then blended with a vegetable gum (gum ghatti) to prevent the tiny particles from clumping back together. This process dramatically increases curcumin solubility and bioavailability.5-7

Theracurmin® is vastly more bioavailable than regular curcumin powder, ensuring an effective level in the blood. Published studies comparing blood levels of curcumin confirm that Theracurmin® is better absorbed than other forms of curcumin.5-7

Scientific scrutiny confirms that Theracurmin® is more bioavailable on a milligram-to-milligram basis than other enhanced and regular forms of curcumin.5-7 

Curcumin Clarity for All

By now, you may be thinking, “but turmeric has been used for thousands of years; why do we need modern technology to benefit from it?” That’s a logical question. Indeed, the health of populations who consume turmeric regularly pointed toward its beneficial effects.

The benefits seen in modern clinical trials using advanced-absorption curcumin extend far beyond what was seen in population-based, observational studies of people who eat turmeric. So enjoy curry regularly. But if you want to experience the full benefits of curcumin, reach for Theracurmin®.5

When it comes to curcumin, it’s not how much you take, but how much you absorb that matters. It can be difficult or impossible to judge how much of it will be absorbed from the amount of curcumin on a supplement label.

You can go back to drinking regular chai lattés now. You’re welcome.

References

Prasad S, Aggarwal BB. Turmeric, the golden spice: From traditional medicine to modern medicine. In: Benzie IFF, Wachtel-Galor S, editors. Herbal medicine: Biomolecular and clinical aspects. 2nd ed. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 13. Available from: https://www.ncbi.nlm.nih.gov/books/NBK92752/

Ghosh S, Banerjee S, Sil PC. The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent update. Food Chem Toxicol. 2015 Sep;83:111-24. doi: 10.1016/j.fct.2015.05.022. Epub 2015 Jun 9. 

Lao CD, Ruffin 4th MT, Normolle D, et al. Dose escalation of a curcuminoid formulation. BMC Complement Altern Med. 2006; 6:10.

Shoba G, Joy D, Joseph T, et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998; 64(4):353-6.

Imaizumi A. Highly bioavailable curcumin (Theracurmin): Its development and clinical application. PharmaNutrition. 2015 Oct 1;3(4):123-30.

Sasaki H, Sunagawa Y, Takahashi K, Imaizumi A, Fukuda H, Hashimoto T, Wada H, Katanasaka Y, Kakeya H, Fujita M, Hasegawa K, Morimoto T. Innovative preparation of curcumin for improved oral bioavailability. Biol Pharm Bull. 2011;34(5):660-5.

Chung H, Yoon SH, Cho JY, Yeo HK, Shin D, Park JY. Comparative pharmacokinetics of Theracurmin, a highly bioavailable curcumin, in healthy adult subjects. Int J Clin Pharmacol Ther. 2021 Oct;59(10):684-690. 

[microbzcouk]

MicrobzPedia - A Comprehensive Resource on Microbes, Herbs, and Minerals for Health

MicrobzPedia serves as an extensive educational resource that provides insight into the various ingredients used in Microbz's probiotic products. It highlights the benefits of probiotics and the role of different microbes, herbs, and minerals in supporting health and wellness. MicrobzPedia aims to educate consumers about the significance of diverse strains of beneficial bacteria and other elements crucial for maintaining optimal health, positioned as a trustworthy source in the health supplement market.

[dogcancerfoundation]

The Truth About CBD with Food

According to research, taking CBD with food may have a significant impact on the amount of CBD absorbed by the body. The importance of bioavailability cannot be overstated. For the best effect, your dog will need to take more CBD if the bioavailability is low. The higher the bioavailability, the better the results. How to Provide CBD to Dogs In the past, scientists believed administering CBD on…

[alldruginfo]

Edibles or Smoking: The Better Way to Enjoy Cannabis?

Cannabis consumption has become increasingly mainstream, leading to a variety of methods for enjoying its effects. Among these, edibles and smoking stand out as the most popular options. Each method offers unique experiences, benefits, and challenges, making the choice between edibles and smoking a matter of personal preference and lifestyle. This article explores the key differences between these two methods, examining their health impacts, effectiveness, and suitability for different users.

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