#Cbd Life Oil Benefits

[sergeant-angels-trashcan]

Thinking about disabled AK!Jason tonite with a disabled s/o

Let's be fr this man could/should be an ambulatory wheelchair user but he won't because he doesn't know that's a thing and wouldn't think he deserved it. If you're an ambulatory wheelchair user maybe one day you manage to lovingly bully him into just TRYING it and it is life changing

He uses his ambulatory energy to do Red Hood shit nbd

if he doesn't use a wheelchair he's got at least 2 braces--shoulder and knee

Baby has chronic pain, arthritis, chronic migraines from being beaten

Missing some teeth too

take this boy to your neuro or your ortho!!!! he is totally unaware he does not need to live like this. better living through chemistry

let's get him some therapy too

you WILL have to go to his drs appointments with him. mans WILL freak the fuck out for ANY medical procedure, has very serious medical abuse trauma. if he can see how your drs help you he is much more likely to go if he can see that you are benefiting from your providers and that they haven't harmed you

if you're scared of drs he will FULLY stand behind you. probably not that healthy tbh but he gets it

having a special Migraine Protocol for each of you (it's basically just a snack and a drink, blue light filter glasses, a sleep mask with headphones for that special Migraine Playlist)

make your own pain scales and talk through frequency of pain bc when you have constant or near constant pain it fucks up your ability to quantify it so making your own pain scale is helpful (he probably uses shakespeare plays or authors. like a 5 for jason is twilight, because you can see some problems but it's fun and fluffy but when you start looking closer OH NO SO MANY PROBLEMS)

pain meters on a wall near the kitchen so you can know what you're working with

CBD patches

the AK suit is basically a giant brace/mobility aid so you help him figure out how to adapt it for his red hood persona, how to make it lighter and allow for greater ROM

will remind you to do physical therapy

resistance bands ALL OVER THE HOUSE

learning bodywork techniques

AT LEAST once a week using a special oil or lotion to work into some of his bigger scars to make the tissue more mobile

giving him a back/neck/scalp/face massage

after a while obvi that's a lot of trust he's putting in you

NOT deep tissue. don't hurt him more. you can have effective therapeutic massage without hurting a person

trager work involves basically shaking a limb and letting the weight of the muscle do all the work but it feels weird the first time and he'd just start laughing at you

specially if you do his glutes

but it feels really nice so he stops laughing and it does help his lower body pain

putting magnesium lotion on each other's neck and shoulders

start to ask each other "are you angry or in pain?"

hand massages

teaching him to stop pushing through the pain

one of his knees is basically bone on bone so you always know when the weather is changing

if u both have bad knees u just don't even when the weather is changing. take some pain meds, use your topical pain reliever of choice, prop those joints up and snuggle in bed. watch a youtube series or he can read to you

heated blankets as heating pads supremacy

occasionally he'll be in pain and the kind of pain where you feel like you're going insane, so as a distraction he will go online and buy a bunch of weird pain-relieving gadgets and you'll spend a week trying them out

(sometimes his pain fog shopping spree is blind boxes, or nail polish, or statement shirts)

all of his siblings know to come to your place if they get beat tf up because your medicine cabinet is UNreal

you're about to give cass or steph a Controlled Substance Pain Reliever and you pause "this is technically drug dealing, isn't it? dOn'T teLL rEd hOOD" jason is literally patching them up right next to you

soft blankets

reminding each other it's ok to take it slow

he's constantly tearing into the other rogues for not having ADA accessible lairs (except Ivy who successfully argued that the plants make it ADA accessible which will do. FOR NOW.)

[ireton]

DISCLAIMER: Please do your own research and come to your own conclusions.

When you tell someone a medicine for dogs cured your cancer, you better be ready for some skeptics, but Joe Tippens says it saved his life, and the lives of others.

Now, even cancer researchers are open to the possibility it might be true."My stomach, my neck, my liver, my pancreas, my bladder, my bones -- it was everywhere," Tippens said. Tippens said he was told to go home, call hospice and say his goodbyes two years ago. The doctors were unanimous, he was going to die of small cell lung cancer.

"Once that kind of cancer goes that far afield, the odds of survival are less than 1 percent, and median life expectancy is three months," Tippens said. Tippens said he went from 220 pounds to 110. "I was a skeleton with skin hanging off of it," he said. "It was difficult."

But that was January of 2017. Today, Tippens is very much alive and what he credits for his survival has doctors scratching their heads, and the rest of us raising eyebrows. "About half the people think I'm just crazy," he said. "And about half the people want to know more and dig deeper."

Tippens said he received a tip from a veterinarian, of all people. And in his desperation, he turned from people medicine to dog medicine. Specifically, something you give your dog when it has worms. "The truth is stranger than fiction, you know?" Tippens said, laughing. Just three months later, Tippens says, his cancer was gone.

"I'm usually skeptical, and I was and maybe still am about this one," said Stephen Prescott, president of the Oklahoma Medical Research Foundation. "But there's interesting background to this." Cancer researchers like Prescott are skeptical, but they also are not dismissing this anti-parasitic's potential. He says Tippens is not the first person to potentially benefit, and not the last.

"Scientists and many credible places have done work on this for years," Prescott said. But was it the de-wormer, or was it something else? Tippens took the dog medicine with daily vitamin E supplements and CBD oil. He was also taking an experimental cancer-fighting drug. But Tippens says out of the 1,100 patients on that clinical trial, he was the only one cleared of cancer.

Tippens says he was saved by the dog de-wormer and he plans to take it for the rest of his life. "My insurance company spent $1.2 million on me with traditional means before I switched to a $5 a week medicine that actually saved me," he said. Prescott says he's now working with Tippens to organize a case study.

"We're going to do it and see if we can confirm, in a very rigorous and clinical sort of way, that these patients had that kind of response," Prescott said. As for Tippens: "I've got over 40 success stories other than me," he said. He's sharing his story on an online blog that has been read more than 100,000 times. Most of the feedback is positive, or curious.

Some accuse Tippens of giving cancer patients false hope. "Oh, how do I answer that?" he sighed. "I mean, if I've saved one other person other than me, it's worth it to me." All we know for sure is that Tippens is alive. In time, perhaps we'll also know if this medicine made for man's best friend might also be man's newest cancer cure.

[mittenwonders]

Leaving this here

As I’ve said 5000 times before - I am not against MEDICAL marijuana or CBD oil use. I voted in my state for the legalization of it so that I can use CBD oil (as I have chronic illnesses). What I AM against is the recreational use of smoking marijuana as it’s a public health concern, hence why it was banned before in the first place and still banned in most countries around the world. And yes I am a liberal and have wrote my concerns to my legislators and senators about this concern because it’s important to me and near to my heart. No, I will absolutely not date anyone who purposely partakes in it like it’s no big deal.

The THC aspect is what everyone glosses over in the difference of reaping the benefits. THC is what kills the brain and nerves throughout a persons body. THC is microscopic in CBD products at under 0.034%. You can even opt for CBD products with zero THC at all, as the main component is the hemp leaf itself and the cannabinoids that work with our body’s endocrine system. You do not get “high” off CBD products. You get relaxed but in no way do you forget things or lose sense of anything at all. It doesn’t mess with your mind. I support CBD and the research being done to try to clear this as FDA approved medicine for patients with insomnia, anxiety, depression, arthritis and chronic pain. CBD is what was approved by the FDA for seizure disorders, not weed. It’s helped my arthritis tenfold but it costs $$$ out of pocket to secure.

THC however has the opposite effect on the nervous system and brain and this has been researched to cause insomnia, anxiety and depression within people who use regularly. THC will lead to more mental health issues down the line. There is a reason doctors ask if you smoke and if you say yes, they ask what kind. Not only does it cause lung damage but it also leads people to a higher risk of stroke. Many people who stop using after long periods of time do develop sweats, jitteryness and talk about suddenly having a clear mind and less paranoia. It’s literally the textbook definition of withdrawal which means addiction.

I understand addiction is a disease and I am sorry most people felt they needed to turn to a substance in order to cope at some point in their life. However I will not support another recreational item that will destroy someone or their family. We already deal with alcoholism and other substance abuse in this country. Legalizing another is asking for more issues. I will always stand with someone who is willingly wanting to change and seek help because clearly they want it. But I won’t stand around someone who doesn’t even try or want to try. As a former alcoholic who comes from a family of alcoholism, I understand the struggle but the lightbulb moment has to come from within and you have to want the sobriety yourself. You also have to change your environment to heal. I can’t be around other people who drink. It’s too much of a temptation nor can I be around people that when I say “no thank you” they continue to question why or try to say “oh come on! It’s one drink!” Those are not your people and will be your downfall. You have to respect yourself and love yourself enough to walk away from anything and anyone that doesn’t serve you. If all your friends drink or do drugs or smoke weed, well then you don’t want to get better.

[beakers-and-telescopes]

Link to actual study: https://pubs.acs.org/doi/10.1021/acsami.3c04036

Most people know of CBD's benefits at treating chronic pain and anxiety, but some studies have also shown that it helps limit microbial and fungal growth. A research team in Thailand wanted to discover if this quality could be harnessed to create an edible coating that could keep strawberries fresher, longer (spoiler: it can!).

Before they could test CBD's effects on food freshness, they needed to find a way to distribute the oil evenly in water. The method that they used involved creating nanoparticles consisting of a CBD molecule surrounded by an edible polymer that is commonly used in drug delivery, poly(D,L-lactide-co-glycolide). Surrounding the oil in this polymer allowed it to easily mix with the water instead of separating out to the surface. The most stable of these particles that were selected for the study contained about 20% CBD by weight. These were added in different concentrations to a solution of water and sodium alginate, which is a current antimicrobial coating for fruits.

Strawberries were dipped into the nanoparticle solution for two minutes, followed by a dip in another solution to solidify it into a thin gel layer. Then, they were left in an open container at fridge temperature for 15 days. The strawberries treated with the highest concentration of CBD nanoparticles performed the best on all levels- they maintained their dark red color, had increased antioxidant activity, and were protected from microbial growth. These results are preliminary, but they certainly suggest potential for CBD oil to be used to keep your food fresh!

[luxurymassageoil]

Elevate Your Relaxation with CBD Luxury Massage Oil

In the hustle and bustle of American life, we all crave those precious moments of peace and relaxation. Enter CBD Luxury Massage Oil, a true game-changer that seamlessly blends the calming prowess of CBD with the therapeutic joys of massage. Let’s take a journey into the world of CBD Massage Oil and discover why it’s become the go-to choice for folks across the USA seeking a touch of luxury and rejuvenation.

CBD, short for cannabidiol, is a natural compound extracted from the hemp plant. What makes it stand out? Well, it’s non-psychoactive, meaning it won’t leave you feeling spaced out. Instead, it’s celebrated for its potential to bring a sense of calm and relaxation. And when you infuse it into a top-quality massage oil, magic happens.

Why is CBD Luxury Massage Oil making waves? For starters, it’s a relaxation powerhouse. CBD has a unique way of interacting with our endocannabinoid system, which plays a starring role in managing stress, anxiety, and mood. When you rub in that CBD goodness through a massage, it’s like a wave of tranquility washing over you — perfect for unwinding after a hectic day.

But that’s not all. CBD is also earning its stripes for potential anti-inflammatory and antioxidant effects. Translation: CBD Massage Oil isn’t just a treat for your senses; it’s a balm for your body. Whether you’re an athlete recovering from a hardcore workout or just dealing with the usual aches and pains, this oil could be your new best friend.

Now, when you’re on the lookout for CBD Luxury Massage Oil in the USA, quality is key. Reputable brands put their products through rigorous third-party testing, ensuring you’re getting the good stuff without any unwanted extras. And here’s a tip: go for organic, full-spectrum CBD for the full package of benefits — what they call the entourage effect.

The carrier oils in CBD Massage Oil play a starring role too. Think jojoba, sweet almond, or coconut — these aren’t just there for show. They nourish your skin and amp up the glide and absorption of the CBD. The end result? A massage oil that not only feels like pure luxury but also leaves your skin thanking you.

Adding CBD Luxury Massage Oil to your self-care routine is like giving yourself a little slice of heaven. Whether you’re treating yourself to a professional massage or DIYing it at home, that added touch of CBD turns it into a moment of pure bliss and rejuvenation.

Of course, a friendly reminder: chat with a healthcare professional before diving in, especially if you have health conditions or are on medications. And always stick to the usage guidelines on the bottle for a safe and delightful experience.

In a nutshell, CBD Luxury Massage Oil offers a holistic approach to relaxation and well-being in the USA. By blending the therapeutic powers of CBD with top-notch carrier oils, it’s not just a massage; it’s an experience. So why not elevate your massage game with CBD Luxury Massage Oil? Your path to serenity awaits right here in the United States.

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[stellasvane]

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[jenniferashtoncbdgummyus]

Jennifer Ashton CBD Gummies - (2023 Pain Relief) Reviews, Quit Smoking & Real Facts!

➢Supplement Review - Jennifer Ashton CBD Gummies

➢Benefits – Reduce Stress & Pain Relief

➢Base Ingredients - Magnesium-BHB

➢Side Effects - No Major Side Effects

➢Dosage - 2 Gummies per day

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Jennifer Ashton CBD Gummies:- Jennifer Ashton CBD Gummies components help to present alleviation to extraordinary health problems, like pressure or pain. CBD reaches each area in which the ache is and reduces the ache for some time. A every day dose of this medicine can supply remedy to unique styles of frame elements, like joints, legs, palms, or back pain issues. If a person has serious headache or neck ache kind troubles, in an effort to deficiently move for this CBD.

The substances help in improving the general temper and supply relief to the frame and mind. It works for some time, however it is no longer a permanent answer. It improves bodily appearance and makes the body more potent, and if someone is fit mentally, so they may do productive matters. They mechanically begin getting mind alleviation, or any ache does no longer harm plenty while their frame is robust sufficient to address it.

Benefits of taking Jennifer Ashton CBD Gummies:-

A Jennifer Ashton CBD Gummies: gives many blessings as it's obviously get made, so it does now not show any side outcomes at the body. There are many blessings of taking those CBD gummies: -

Reduce ache in the frame: In latest global, the general public don't have sufficient time to spend on their body health. And extra workloads result in pain inside the lower back, legs, head, and neck, or distinct components of a body. These gummies assist in decreasing pain so human beings can get some comfort from ache for a temporary time. A lengthy workday reasons inflammation, and this gummy facilitates in decreasing it.

Increase intellectual capability: Daily workload decreases the mind's attention or potential. The CBD facilitates in increasing cognizance and gives alleviation to the mind, so it is able to paintings with new electricity. It makes intellectual health stronger for fighting workloads, and on the cease of the day, it also works as a remedy. A each day dose of CBD can give higher outcomes.

Brain improvement: Ingredients of this medication make reminiscence power strong and thoughts sharp after some weeks of the use of it. It improves the brain cells, and every dose of CBD makes it higher and improves the energy of the brain to do things with a smart mind. It's an awesome choice for those who face a reminiscence loss type hassle.

Reduce pressure: Stress becomes a commonplace component in all and sundry's life, and it shows an impact on the body, thoughts, and even the life-style of a person. This CBD helps in lowering any sort of tension or strain. It gives rest and reduces anxiety, and people feel more active and efficient after taking this remedy. It additionally offers a wholesome sleep, which is likewise a terrific element for a stress-free thoughts.

Helps in losing weight: It burns bad energy from the frame and burns a few extra fat from the stomach, thigh, or neck type of areas. It increases muscular strength without growing the load inside the frame. It offers an excellent amount of oxygen and blood to the heart, that's allows in improving the fitness of the cardiovascular gadget of the frame.

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How to apply Jennifer Ashton CBD Gummies?

There are diverse styles of CBD, like Oil for outside use, and gummies can get taken as a pill. People can take gummies one time within the day, or they could comply with instructions given through makers of CBD. People can also go to the physician for higher information approximately taking it on the proper time, however there may be no unique time for taking CBD gummies. Just take it with a few water, like any other scientific pill.

If someone has an oil form of CBD, that could get jumbled in food, humans can degree the quantity with any eye drop tube kind of tool, and then they could mix it with the Oil of their food. The medicinal drug takes time round 8 hours for correct digestion within the frame. It does now not make the food taste worst however increases the benefits of ingesting food with the beneficial based CBD.

Side consequences of using Jennifer Ashton CBD Gummies:

People do now not get hooked on these gummies like another drug, which additionally makes humans high. Overdosing of this remedy also does now not have any dangerous consequences at the body. Some outcomes can get occur but on the minor lever, and that's why usually test some health-related information earlier than shopping for it.

If a person faces any problems after beginning taking these gummies, so does not hold taking them, and visit a medical doctor to recognize the cause for the outcomes. If someone has any problem with their frame, so constantly consult a medical doctor earlier than shopping for, d if according to health practitioner it does no longer affect the health so all and sundry can pass for it.

How do these drugs assist your body in other ways?

We have already discussed several benefits of taking Jennifer Ashton CBD Gummies each day. Now, let us talk some moiré blessings of taking these pills daily:

They may also assist to get higher mental clarity.

You may get better mood styles after taking these pills daily.

Your mind-set can also exchange undoubtedly after taking those capsules often.

These pills can also reduce depression and tension inside a few weeks.

They may not include THC or other poisonous factors.

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Tips for clients:-

People can devour one Jennifer Ashton CBD Gummies: every day, and in the event that they do now not get any side consequences from it so that they can increase the dosage from one to 2, not more than this. Consuming gummies each day is constantly an excellent desire.

It does no longer need recommendation from a doctor, but it still everybody feels to ask if you want to cross for it. This medicine isn't always made for small youngsters or ladies who're pregnant due to the fact this could show extreme side effects on their bodies. Don takes too big an quantity due to the fact it may have an effect on the sleep schedule.

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[associatedcbd1]

CBD Gummies

CBD (Cannabidiol) gummies have become increasingly popular as a way to enjoy the benefits of CBD in a tasty and convenient way. These gummies are made with CBD oil, which is extracted from the hemp plant, and they offer a variety of potential health benefits without the psychoactive effects of THC. In this article, we’ll take a closer look at CBD gummies, their benefits, and some things to consider before purchasing them.

What are CBD gummies?

CBD gummies are small, chewable candies that are infused with CBD oil. They come in various flavors, shapes, and concentrations of CBD, so you can choose the one that best suits your needs. Some CBD gummies are also infused with other ingredients like melatonin, which is known to promote sleep, or vitamin C, which is a powerful antioxidant.

What are the benefits of CBD gummies?

CBD has been the subject of much scientific research over the past few years, and the results have been promising. Some of the potential benefits of CBD gummies include:

Pain relief: CBD has been shown to reduce pain and inflammation in various studies. This is particularly useful for people suffering from chronic pain conditions like arthritis.

Anxiety relief: CBD has been shown to reduce anxiety in people with social anxiety disorder, post-traumatic stress disorder (PTSD), and other anxiety disorders.

Improved sleep: CBD has been shown to improve sleep quality and duration in people with insomnia.

Neuroprotective properties: CBD has been shown to have neuroprotective properties, which means it can help protect the brain from damage caused by injury or disease.

Anti-seizure properties: CBD has been shown to be effective in reducing the frequency and severity of seizures in people with epilepsy.

What to consider before purchasing CBD gummies

When it comes to purchasing CBD gummies, there are a few things to consider:

The concentration of CBD: CBD gummies come in various concentrations of CBD, so it’s important to choose the one that best suits your needs.

The quality of the CBD: It’s important to choose CBD gummies that are made from high-quality, organic CBD oil. This ensures that you’re getting the most benefits from the CBD and that there are no harmful contaminants.

The ingredients: Make sure to read the label carefully and choose CBD gummies that are made with natural, healthy ingredients.

The brand: Choose a reputable brand that has a good reputation for quality and transparency.

In conclusion, CBD gummies are a tasty and convenient way to enjoy the potential health benefits of CBD. They offer a variety of benefits, including pain relief, anxiety relief, improved sleep, and neuroprotective and anti-seizure properties. When purchasing CBD gummies, make sure to consider the concentration of CBD, the quality of the CBD, the ingredients, and the brand. With these factors in mind, you can enjoy the benefits of CBD gummies and take the first step towards a healthier, more relaxed life.

[clinereeves33]

Royal Oak City Council Keeps Medical Marijuana Rulings But Protest Will Continue

MSM eye drops are made on the web and are inexpensive. A little side note, use them for the eye area and have more health improvements. Using MSM in your eyes will insure that a normal have Glaucoma. Again MSM will make tissue permeable and the desire release pressure form the eyeball - Glaucoma- or release pressure from behind the eardrum bring the eardrum back to normal.

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[leebird-simmer]

All About: Cannabis

History

- Cannabis probably originated in China. Medical and religious use can be traced to ancient China, India, Egypt and the Middle East.

- At the beginning of the 19th century, Napoleon’s soldiers brought cannabis to France from Egypt in the form of hashish.

- It became very popular with French writers and artists, who established Le Club des Hachichins (The Hashish-Eaters’ Club) in Paris.

Members included Theophile Gautier, Charles Baudelaire, Victor Hugo, Honore de Balzac, and Alexandre Dumas

- Hemp was grown in colonial America, but marijuana smoking probably came to the US with Mexican & Caribbean immigrants in the early 1900s.

- Cannabis (hemp) plant:

High THC content ---> Marijuana, recreational use

Low THC content (less than 0.3%) = industrial hemp

- In 1937, the Marijuana Tax Act instituted a national registration and taxation system aimed at discouraging all use of cannabis. It was overturned in 1969.

- Largely destroyed the hemp industry {note: this benefited paper manufacturers and thus indirectly benefited logging companies}

- United States Department of Agriculture lifted the tax on hemp cultivation during WWII

Legal Status

- In 1970, marijuana and THC became Schedule I illegal drugs.

2014 Farm Bill: permits cultivation of industrial hemp for research purposes

2018 Farm Bill: made industrial hemp legal, allowed CBD oil production

Preparation

- Marijuana is produced from flowering hemp (Cannabis sativa).

- Marijuana is a mixture of dried and crumbled leaves, small stems, and flowering tops.

- Hemp seeds have been used for oil and bird food.

- It can be consumed orally, as in cookies or brownies, but is usually smoked in rolled cigarettes known as “joints,” various kinds of pipes, or in hollowed-out cigars called “blunts.”

- Hashish is a cannabis derivative that can be smoked or eaten.

- It can refer to a relatively pure resin preparation with very high cannabinoid content, or a solvent extract of leaves or resin.

- Hash oil is an alcohol extract. A drop is placed on a tobacco or marijuana cigarette.

Ingredients

- Hemp contains 70 unique compounds known as cannabinoids, plus more than 400 other identified compounds.

- The psychoactive compound /_\9-tetrahydrocannabinol (THC) accounts for the use of cannabis as a drug. {note: that’s supposed to be a triangle; sorry}

- Marijuana potency (in terms of THC content) varies widely, depending on the genetic strain of the plant and growing conditions.

- Potency can be increased by preventing pollination and seed production by the female plants. This marijuana is called sinsemilla (”without seeds”).

- THC was identified as the major active ingredient in 1964.

- Burning marijuana causes the THC to vaporize and enter the smoker’s lungs in small particles.

- Effective dose and latency to onset of effects are influenced by the amount and potency of the plant used, and patterns of smoking (e.g. duration of held breath).

Administration & Absorption

Smoking

- Smoking marijuana is the quickest way to absorb THC, with blood levels peaking between 9-10 minutes into a smoke session.

- THC is easily absorbed by the lungs, and blood plasma levels rise quickly.

Edibles

- Thought to yield peak THC blood levels within 1-5 hours post-ingestion

- Poor absorption results in low and variable plasma levels, probably due to degradation in the stomach, first-pass metabolism.

Elimination

- Blood THC levels decline rapidly after smoking marijuana, but complete elimination from the body is much slower because of persistence in fat tissues.

- Half-life varies from a few hours to 3-4 days

- The gradual movement of THC metabolites back out of fat stores means that urine screening tests can detect them more than 2 weeks after a single incident of marijuana use.

Acute Behavioral Effects

- Effects of cannabinoid use vary depending on dose, frequency of use, characteristics of the user, and the setting in which use occurs.

- Subjective & behavioral effects of marijuana use can be separated into four stages: the “buzz,” the “high,” the stage of being “stoned,” and the “come-down.”

The “high” is associated with feelings of euphoria & exhilaration, and a sense of disinhibition.

Relaxation is the most commonly reported effect of being “stoned.”

- Smoking marijuana can sometimes produce transient psychotic symptoms such as depersonalization, derealization, agitation, and paranoia.

- Expectation also plays a role in what effects the drug will produce, as shown by placebo studies.

- Marijuana negatively affects cognitive functions.

Decreased performance for a variety of verbal, spatial, time estimation, and reaction time tasks has been noted.

Cannabinoids appear to interfere with all aspects of memory processing.

- Marijuana can affect psychomotor functioning under demanding task conditions, such as driving.

- Use of cannabis with or without alcohol is a risk factor in automobile accidents.

Acute Physiological Effects

- increased blood flow to the skin and flushing

- increased heart rate

- increased hunger

Chronic Behavioral Effects

- In young people amount of cannabis use is inversely related to educational performance.

- Some research supports the hypothesis that heavy cannabis use leads to persistent cognitive defects, impairing school performance.

- Alternatively, poor school performance and rejection of mainstream values (such as educational achievement) may increase cannabis use.

- Chronic cannabis use can also result in aimlessness, decreased motivation, lack of planning, and decreased productivity (amotivational syndrome).

{note: Amotivational syndrome can also be caused by SSRIs, and since there is a high rate of comorbidity between depression + anxiety, and between cannabis use + depression and/or anxiety, it can be difficult to determine whether SSRIs or cannabis are causing amotivational syndrome in patients who use both substances.}

- Heavy cannabis use over a long period may lead to impaired executive functioning for at least 2-3 weeks following cessation of use.

- Some data suggest that heavy, long-time users may continue to show impairment in decision-making, planning, and concept formation. It may negatively affect the prefrontal cortex.

- Imaging studies suggest that chronic marijuana use is associated with several kinds of abnormalities in the brain.

- Several studies have found a significant relationship between early heavy marijuana smoking and increased risk for later development of psychotic disorders such as schizophrenia.

Mechanisms of Action

- A cannabinoid receptor in the CNS was identified in 1988.

- Receptors occur in many brain areas.

- Localization of cannabinoid receptors in these areas is consistent with the behavioral effects of these compounds on locomotor activity, coordination, and memory.

- Endogenous neurotransmitter-like substances that act on the receptors = endocannabinoids.

- Two main endocannabinoids have been found: anandamide and 2-AG.

- They are retrograde messengers; they carry information in the opposite direction from normal (i.e. postsynaptic to presynaptic).

- THC similar to endocannabinoids binds to cannabinoid receptors located presynaptically on the nerve terminal. They are metabotropic: they work via G-proteins to inhibit presynaptic voltage-sensitive Ca2+ channels, and open K+ channels.

- As a result, cannabinoids decrease neurotransmitter release from the terminal.

Reinforcement

- In one study, regular marijuana users could discriminate THC-containing marijuana cigarettes from placebos with no THC, and all subjects preferred the marijuana with THC when given a choice.

- Animal studies have also demonstrated reinforcing properties.

Lever pressing by squirrel monkeys for THC stopped when placebos were used.

- Mechanisms for reinforcement:

Activation of the mesolimbic dopamine system: VTA --> NAcc

Interactions between the cannabinoid and opioid systems may play a role in cannabinoid reward and reinforcement; opioid agonists enhance cannabinoid self-administration, and opioid antagonists have the opposite effect.

Tolerance & Dependence

- Animals exposed to THC or other CB1 agonists develop tolerance to the behavioral and physiological effects of these compounds.

- It appears to involve a combination of desensitization and down-regulation of CB1 receptors.

Adverse Health Effects

- There are no reports of death from overdose.

- Smoking marijuana can damage lungs: smoke contains tar, other carcinogens, carbon monoxide, etc.

- Possible adverse cardiac effects?

- Immune system suppression

- THC may affect reproductive functions:

In AFAB people, it can affect ovulation.

In AMAB people, regular smoking has been shown to decrease testosterone levels and sperm counts.

Animal research has demonstrated pregnancy failure, delayed embryonic development, and even fetal death with THC administration.

Smoking marijuana during pregnancy results in cognitive deficits, poor school achievement, and increased risk for tobacco and/or marijuana use later in life.

DSM-5: Cannabis Use Disorder

- Marijuana use typically begins in adolescence and peaks during young adulthood.

- If an individual has not yet tried marijuana by their mid-twenties, they are unlikely to begin at a later age.

- Cannabis use varies based on demographics.

- Research shows college students and young adults most commonly use cannabis...

To socially conform (~40%)

To experiment (~30%)

For enjoyment (~20%)

To manage stress or relax (~10%)

- Risk of dependence is related to drug use patterns. People who progress to daily use have a 10-20% probability of becoming dependent.

- Dependence manifests as a difficulty in stopping one’s use, a craving for marijuana, and (in heavy users) unpleasant withdrawal symptoms:

irritability

increased anxiety

depressed mood

sleep disturbances

heightened aggression

decreased appetite

- These are similar to the symptoms of nicotine withdrawal.

Treatment

- Most cannabis users do not seek treatment.

- Treatment in outpatient programs involves cognitive-behavioral therapy, relapse prevention training, and/or motivational enhancement therapy, but patients are very vulnerable to relapse.

- Some research on medications to relieve withdrawal symptoms has been done.

Therapeutic Uses of Cannabinoids

- AKA “medical marijuana”

- Many states now permit legal use, but clinical studies of its efficacy have produced mixed results.

- Smoked marijuana has the highest potential for adverse health effects and abuse; most researchers favor development of cannabinoid-based drugs instead.

- Information from the National Institute of Health

- The FDA has not approved the cannabis plant for any medical use. However, the FDA has approved several drugs that contain individual cannabinoids:

Epidiolex, which contains a purified form of CBD derived from cannabis, was approved for the treatment of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome, two rare and severe forms of epilepsy.

Marinol and Syndros, which contain dronabinol (synthetic THC) to treat nausea and vomiting caused by chemotherapy. Dronabinol is also used to treat loss of appetite and weight loss in people with HIV/AIDS.

- Endocannabinoids enhance the incentive motivational properties of food and food-mediated reward.

- CB1 receptor antagonists reduce food consumption in animals and human subjects.

- In animal studies, marijuana was shown to relieve anxiety and depression.

- There’s some evidence that marijuana might reduce addiction and/or overdoses caused by other drugs.

- Pain perception: transgenic mice that lack CB1 and CB2 receptors demonstrate hyperalgesia (increased pain sensitivity).

- Clinical evidence for cannabinoids as analgesics has not been convincing.

- Nabiximols (Sativex) is a cannabis extract.

was approved in the UK in 2010 to treat pain and spasticity in multiple sclerosis patients (not yet approved in the US)

- A number of years ago, Jamaican researchers prepared eye drops from cannabis extracts (trade name Canasol) for the purpose of reducing ocular pressure in glaucoma patients.

However, the research is inconclusive and Canasol was never licensed by the FDA for legal marketing in the United States.

[hemp-co]

Hemp Seed Oil For Pets | Health Benefits And Uses

First things first: Anything with an endocannabinoid system can benefit from hemp.

Hemp seed oil for pets is a fascinating topic, especially considering its incalculable benefits. But even though it has such an impressive array of advantages, pet owners are often oblivious to this amazing natural herb… and fair enough, it’s been illegal and misportrayed for so long! 

But this is no longer the case, so we want to help spread the word of how everything on this planet can benefit from hemp – not just humans.  

…So don’t worry if you haven’t heard much about it yet.  In this article, we’re going to bring you up to speed on all the benefits of hemp seed oil for your pets – dogs and cats alike!

Hemp Oil Vs. Hemp Seed Oil For Pets… What’s The Difference?

Hemp oil (also known as CBD oil) is a medicinal product that’s manufactured from the flower of the female Cannabis sativa plant. It’s quite high in cannabidiol (CBD) and other cannabinoids and can contain THC, the compound that is reported by Wikipedia to be the principal psychoactive in cannabis.

This is one of the main ‘medicinal cannabis oils’ that we’ve been hearing so much about recently!  As it seems, it’s becoming widely used for pain relief for humans and pets across the world. Hemp Oil is essentially a concentrated extract of the medicinal compounds of the cannabis plant, and therefore contains high amounts of cannabinoids. 

Hemp seed oil, on the other hand, is the oil extracted by cold-press from the seeds of the same cannabis plant.  Legally speaking, hemp seed and hemp seed oil in Australia should have less than 0.3% THC to be sold. This oil contains only slight traces of THC and CBD.

Therefore, you can legally use hemp seed oil without a prescription for yourself or your pet animals in Australia. The composition of the hemp seed oil is perfect for pets. In fact, it’s one of the only natural food in the world that has Essential Fatty Acids (EFA) like Omega 6 and Omega 3 in the optimum ratio of 3:1.

But that’s not all. With a newfound interest in this often-neglected plant, researchers seem to be finding more about the diversity of its benefits every day. Let’s take a look at a few ways that pets can benefit!

Benefits Of Hemp Seed Oil For Pets 

Hemp seed oil can truly be a life-saver for your pet. But that doesn’t mean you need to use it only in times of distress and sickness. In fact, hemp seed oil could – and should – be used in your pets routine diet. Here are a few reasons why!

Improved Skin And Coat

Hemp seed oil can improve skin health in both dogs and cats, leaving them with a fluffy, irresistibly cuddly coat. As mentioned above, hemp seed oil has the perfect composition of Essential Fatty Acids (EFA) like Omega 6 and Omega 3 in the ratio of 1:3.

Omega fatty acids are one of the most important factors for skin and coat health in animals. 

Hemp Out Agency mentions in their article that the unbalanced composition of Omega 6 and Omega 3 in your pet’s diet can cause major upsets in its health. With extra Omega 6, your pet’s body would further reduce its Omega 3 levels.

Similarly, with an excess of Omega 3, the body would cut back on Omega 6. This can lead to serious instabilities in your pet’s body. As a result, other unbalanced sources of Omega fatty acids like fish oil can not be relied upon.

The fact that it is a perfectly balanced source of Omega-3 and omega-6 fatty acids further magnifies the importance of incorporating hemp seed oil in your pet’s diet. 

Treating Skin Allergies

Any oil that is so perfectly balanced with Essential Fatty Acids would certainly work well for skin allergies and diseases. A 2005 research noted that Atopic Dermatitis (Eczema) patients experienced reduced allergic symptoms with the dietary use of hemp seed oil. 

…And that’s just getting started!  There are many other notable benefits of hemp for pets, which you can read more about here

Safe Use And Dosages Of Hemp Seed Oil For Pets 

We often hear questions like, “how much hemp seed oil should I give my dog?” 

Hemp seed oil is comparable to sunflower oil – and is perfectly safe for your pets. It does not contain any psychoactive compounds like THC and includes minimal amounts of CBD as well.

So, you can even incorporate hemp seed into your cat or dog’s meal without fear.  The general rule of safe dosage is 1ml – 5ml depending on your furry friend’s weight.

On the other hand, CBD oil (or hemp oil) is used as medicine and only a vet can prescribe a proper dosage for it. Unfortunately, not much research has been conducted on safe levels of concentrated CBD oil for pets.

Will Hemp Seed Oil Get My Pet High? 

No. Hemp seed oil will not get your pet high. The psychoactive chemical in Cannabis that gives the sensation of being “high” is THC (Tetrahydrocannabinol). With that said, there’s virtually no THC in hemp seed oil. Therefore, our furry friends would have to get into a lot of hemps to get high – just like humans!

All in all, hemp seed oil for pets is not just safe – but highly beneficial as well. 

Check out our Hemp Doggie Treats by clicking here.